LOCUS       DAVKUR010000001       118978 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKUR010000001 DAVKUR010000000
VERSION     DAVKUR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 118978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.001"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            491..1009
                     /locus_tag="VW749_000001"
     CDS             491..1009
                     /locus_tag="VW749_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0174118.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            1139..1645
                     /locus_tag="VW749_000002"
     CDS             1139..1645
                     /locus_tag="VW749_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0174119.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            1645..1815
                     /locus_tag="VW749_000003"
     CDS             1645..1815
                     /locus_tag="VW749_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174120.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            1847..3079
                     /gene="clpX"
                     /locus_tag="VW749_000004"
     CDS             1847..3079
                     /gene="clpX"
                     /locus_tag="VW749_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0174121.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            3088..3675
                     /locus_tag="VW749_000005"
     CDS             3088..3675
                     /locus_tag="VW749_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0174122.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            3686..4066
                     /locus_tag="VW749_000006"
     CDS             3686..4066
                     /locus_tag="VW749_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0174123.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            4118..5008
                     /gene="rapZ"
                     /locus_tag="VW749_000007"
     CDS             4118..5008
                     /gene="rapZ"
                     /locus_tag="VW749_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0174124.1"
                     /translation="MTKKQFHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            5005..5982
                     /locus_tag="VW749_000008"
     CDS             5005..5982
                     /locus_tag="VW749_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0174125.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            5979..6890
                     /gene="whiA"
                     /locus_tag="VW749_000009"
     CDS             5979..6890
                     /gene="whiA"
                     /locus_tag="VW749_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0174126.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(6978..8105)
                     /locus_tag="VW749_000010"
     CDS             complement(6978..8105)
                     /locus_tag="VW749_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0174127.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESD
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(8384..9334)
                     /locus_tag="VW749_000011"
     CDS             complement(8384..9334)
                     /locus_tag="VW749_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEV0174128.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(9483..10274)
                     /locus_tag="VW749_000012"
     CDS             complement(9483..10274)
                     /locus_tag="VW749_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0174129.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAIIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(10518..11207)
                     /locus_tag="VW749_000013"
     CDS             complement(10518..11207)
                     /locus_tag="VW749_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV0174130.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            11414..11578
                     /locus_tag="VW749_000014"
     CDS             11414..11578
                     /locus_tag="VW749_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174131.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            11597..11812
                     /locus_tag="VW749_000015"
     CDS             11597..11812
                     /locus_tag="VW749_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0174132.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            11844..12044
                     /locus_tag="VW749_000016"
     CDS             11844..12044
                     /locus_tag="VW749_000016"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174133.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(12443..12634)
                     /locus_tag="VW749_000017"
     CDS             complement(12443..12634)
                     /locus_tag="VW749_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174134.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            12893..13063
                     /locus_tag="VW749_000018"
     CDS             12893..13063
                     /locus_tag="VW749_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174135.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(13056..13295)
                     /locus_tag="VW749_000019"
     CDS             complement(13056..13295)
                     /locus_tag="VW749_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174136.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            13413..13685
                     /locus_tag="VW749_000020"
     CDS             13413..13685
                     /locus_tag="VW749_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174137.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            13682..13897
                     /locus_tag="VW749_000021"
     CDS             13682..13897
                     /locus_tag="VW749_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174138.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            13876..14064
                     /locus_tag="VW749_000022"
     CDS             13876..14064
                     /locus_tag="VW749_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174139.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            14076..14417
                     /locus_tag="VW749_000023"
     CDS             14076..14417
                     /locus_tag="VW749_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174140.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            14418..14648
                     /locus_tag="VW749_000024"
     CDS             14418..14648
                     /locus_tag="VW749_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174141.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELHRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            14662..15384
                     /locus_tag="VW749_000025"
     CDS             14662..15384
                     /locus_tag="VW749_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0174142.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            15377..15859
                     /locus_tag="VW749_000026"
     CDS             15377..15859
                     /locus_tag="VW749_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0174143.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            15859..16218
                     /locus_tag="VW749_000027"
     CDS             15859..16218
                     /locus_tag="VW749_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174144.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            16218..16703
                     /locus_tag="VW749_000028"
     CDS             16218..16703
                     /locus_tag="VW749_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174145.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            16666..17859
                     /locus_tag="VW749_000029"
     CDS             16666..17859
                     /locus_tag="VW749_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0174146.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            17877..18194
                     /locus_tag="VW749_000030"
     CDS             17877..18194
                     /locus_tag="VW749_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174147.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            18194..19021
                     /locus_tag="VW749_000031"
     CDS             18194..19021
                     /locus_tag="VW749_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0174148.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            19041..19547
                     /locus_tag="VW749_000032"
     CDS             19041..19547
                     /locus_tag="VW749_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174149.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            19720..20541
                     /locus_tag="VW749_000033"
     CDS             19720..20541
                     /locus_tag="VW749_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV0174150.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            20544..21887
                     /locus_tag="VW749_000034"
     CDS             20544..21887
                     /locus_tag="VW749_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0174151.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            22180..22335
                     /locus_tag="VW749_000035"
     CDS             22180..22335
                     /locus_tag="VW749_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174152.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            22332..23027
                     /locus_tag="VW749_000036"
     CDS             22332..23027
                     /locus_tag="VW749_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0174153.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            23185..23445
                     /locus_tag="VW749_000037"
     CDS             23185..23445
                     /locus_tag="VW749_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0174154.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            23445..23903
                     /locus_tag="VW749_000038"
     CDS             23445..23903
                     /locus_tag="VW749_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174155.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            23951..24019
                     /locus_tag="VW749_000039"
                     /pseudo
     CDS             23951..24019
                     /locus_tag="VW749_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            24016..24453
                     /locus_tag="VW749_000040"
     CDS             24016..24453
                     /locus_tag="VW749_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174156.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            24450..24821
                     /locus_tag="VW749_000041"
     CDS             24450..24821
                     /locus_tag="VW749_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174157.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            24894..25298
                     /locus_tag="VW749_000042"
     CDS             24894..25298
                     /locus_tag="VW749_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0174158.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            25379..25461
                     /locus_tag="VW749_000043"
     tRNA            25379..25461
                     /locus_tag="VW749_000043"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25410..25412,aa:Tyr,seq:gta)
     gene            25728..26207
                     /locus_tag="VW749_000044"
     CDS             25728..26207
                     /locus_tag="VW749_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0174159.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDISD"
     gene            26185..27483
                     /locus_tag="VW749_000045"
     CDS             26185..27483
                     /locus_tag="VW749_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0174160.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            27495..28964
                     /locus_tag="VW749_000046"
     CDS             27495..28964
                     /locus_tag="VW749_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0174161.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            28873..29904
                     /locus_tag="VW749_000047"
                     /pseudo
     CDS             28873..29904
                     /locus_tag="VW749_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            30264..30491
                     /locus_tag="VW749_000048"
     CDS             30264..30491
                     /locus_tag="VW749_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HEV0174162.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDVVVIIADDE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            30640..30852
                     /locus_tag="VW749_000049"
     CDS             30640..30852
                     /locus_tag="VW749_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174163.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDS
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            31022..31606
                     /locus_tag="VW749_000050"
     CDS             31022..31606
                     /locus_tag="VW749_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0174164.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            31613..32458
                     /locus_tag="VW749_000051"
     CDS             31613..32458
                     /locus_tag="VW749_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0174165.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            32470..32652
                     /locus_tag="VW749_000052"
     CDS             32470..32652
                     /locus_tag="VW749_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0174166.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            32642..32830
                     /locus_tag="VW749_000053"
     CDS             32642..32830
                     /locus_tag="VW749_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174167.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            32832..33143
                     /locus_tag="VW749_000054"
     CDS             32832..33143
                     /locus_tag="VW749_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0174168.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            33124..33462
                     /locus_tag="VW749_000055"
     CDS             33124..33462
                     /locus_tag="VW749_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174169.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            33437..33952
                     /locus_tag="VW749_000056"
     CDS             33437..33952
                     /locus_tag="VW749_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0174170.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            33949..34317
                     /locus_tag="VW749_000057"
     CDS             33949..34317
                     /locus_tag="VW749_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174171.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            34320..34733
                     /locus_tag="VW749_000058"
     CDS             34320..34733
                     /locus_tag="VW749_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0174172.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            34738..35118
                     /locus_tag="VW749_000059"
     CDS             34738..35118
                     /locus_tag="VW749_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174173.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            35157..35507
                     /locus_tag="VW749_000060"
     CDS             35157..35507
                     /locus_tag="VW749_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174174.1"
                     /translation="MFLDIEGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            35494..39147
                     /locus_tag="VW749_000061"
     CDS             35494..39147
                     /locus_tag="VW749_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174175.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNDFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            39156..39506
                     /locus_tag="VW749_000062"
     CDS             39156..39506
                     /locus_tag="VW749_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174176.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            39511..45126
                     /locus_tag="VW749_000063"
     CDS             39511..45126
                     /locus_tag="VW749_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0174177.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQA
                     SGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNPSGRDGGNPK
                     VTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIK
                     RYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQI
                     STVESTFKQRVNSLEAGVNRLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQ
                     KLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKT
                     VGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQG
                     RNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQ
                     LKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDGENELLVAKTEFKRTADGL
                     STKMAAVESYVGQDGQRQEALQRYTREESTRQATAVRELVNRDFVGKATYQEDVKGIN
                     QRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSE
                     QGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANAD
                     SQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEV
                     GKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFL
                     YSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTS
                     RCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVA
                     DANKKLEATQTKMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLI
                     DRAVIKSAMVDKLKTGNFEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDAFIDRL
                     TSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAG
                     HGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTT
                     FSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKEN
                     ITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLH
                     IDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            45221..45424
                     /locus_tag="VW749_000064"
     CDS             45221..45424
                     /locus_tag="VW749_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174178.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITNNILSIQLDEQREGNQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            45427..45777
                     /locus_tag="VW749_000065"
     CDS             45427..45777
                     /locus_tag="VW749_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174179.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            45787..46086
                     /locus_tag="VW749_000066"
     CDS             45787..46086
                     /locus_tag="VW749_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174180.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            46090..46422
                     /locus_tag="VW749_000067"
     CDS             46090..46422
                     /locus_tag="VW749_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0174181.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            46426..47382
                     /locus_tag="VW749_000068"
     CDS             46426..47382
                     /locus_tag="VW749_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0174182.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(47634..48602)
                     /locus_tag="VW749_000069"
     CDS             complement(47634..48602)
                     /locus_tag="VW749_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0174183.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFVPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            48738..49595
                     /locus_tag="VW749_000070"
     CDS             48738..49595
                     /locus_tag="VW749_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0174184.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            49582..50361
                     /locus_tag="VW749_000071"
     CDS             49582..50361
                     /locus_tag="VW749_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0174185.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            50385..51737
                     /locus_tag="VW749_000072"
     CDS             50385..51737
                     /locus_tag="VW749_000072"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0174186.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            51811..52185
                     /locus_tag="VW749_000073"
     CDS             51811..52185
                     /locus_tag="VW749_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0174187.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            52187..53035
                     /locus_tag="VW749_000074"
     CDS             52187..53035
                     /locus_tag="VW749_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0174188.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASEFPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            53312..54079
                     /locus_tag="VW749_000075"
     CDS             53312..54079
                     /locus_tag="VW749_000075"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0174189.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            54091..55275
                     /locus_tag="VW749_000076"
     CDS             54091..55275
                     /locus_tag="VW749_000076"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0174190.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            55272..57143
                     /locus_tag="VW749_000077"
     CDS             55272..57143
                     /locus_tag="VW749_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0174191.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLTTLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(57286..58470)
                     /gene="mntE"
                     /locus_tag="VW749_000078"
     CDS             complement(57286..58470)
                     /gene="mntE"
                     /locus_tag="VW749_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0174192.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            58774..61470
                     /locus_tag="VW749_000079"
     CDS             58774..61470
                     /locus_tag="VW749_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0174193.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            61483..62274
                     /gene="yghU"
                     /locus_tag="VW749_000080"
     CDS             61483..62274
                     /gene="yghU"
                     /locus_tag="VW749_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0174194.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTESVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            62390..62800
                     /locus_tag="VW749_000081"
     CDS             62390..62800
                     /locus_tag="VW749_000081"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0174195.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            62812..64407
                     /locus_tag="VW749_000082"
     CDS             62812..64407
                     /locus_tag="VW749_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174196.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            64474..64638
                     /locus_tag="VW749_000083"
     CDS             64474..64638
                     /locus_tag="VW749_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0174197.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            64717..65445
                     /gene="yaaA"
                     /locus_tag="VW749_000084"
     CDS             64717..65445
                     /gene="yaaA"
                     /locus_tag="VW749_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0174198.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(65722..66270)
                     /locus_tag="VW749_000085"
     CDS             complement(65722..66270)
                     /locus_tag="VW749_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0174199.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            66591..67079
                     /locus_tag="VW749_000086"
     CDS             66591..67079
                     /locus_tag="VW749_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0174200.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            67076..68263
                     /locus_tag="VW749_000087"
     CDS             67076..68263
                     /locus_tag="VW749_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0174201.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            68256..68621
                     /locus_tag="VW749_000088"
     CDS             68256..68621
                     /locus_tag="VW749_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0174202.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            68637..69983
                     /gene="asnS"
                     /locus_tag="VW749_000089"
     CDS             68637..69983
                     /gene="asnS"
                     /locus_tag="VW749_000089"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0174203.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVKNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            70136..70426
                     /locus_tag="VW749_000090"
     CDS             70136..70426
                     /locus_tag="VW749_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0174204.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            70438..70908
                     /gene="ssbA"
                     /locus_tag="VW749_000091"
     CDS             70438..70908
                     /gene="ssbA"
                     /locus_tag="VW749_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0174205.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            70940..71179
                     /locus_tag="VW749_000092"
     CDS             70940..71179
                     /locus_tag="VW749_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0174206.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            71474..72874
                     /locus_tag="VW749_000093"
     CDS             71474..72874
                     /locus_tag="VW749_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0174207.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSIRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            72876..73235
                     /locus_tag="VW749_000094"
     CDS             72876..73235
                     /locus_tag="VW749_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0174208.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEKKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            73289..74038
                     /locus_tag="VW749_000095"
     CDS             73289..74038
                     /locus_tag="VW749_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0174209.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            74028..74327
                     /locus_tag="VW749_000096"
     CDS             74028..74327
                     /locus_tag="VW749_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0174210.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            74398..75333
                     /locus_tag="VW749_000097"
     CDS             74398..75333
                     /locus_tag="VW749_000097"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0174211.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRIITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            75419..75931
                     /locus_tag="VW749_000098"
     CDS             75419..75931
                     /locus_tag="VW749_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0174212.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            75956..76564
                     /locus_tag="VW749_000099"
     CDS             75956..76564
                     /locus_tag="VW749_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0174213.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            76665..76859
                     /locus_tag="VW749_000100"
     CDS             76665..76859
                     /locus_tag="VW749_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0174214.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(76905..78350)
                     /locus_tag="VW749_000101"
     CDS             complement(76905..78350)
                     /locus_tag="VW749_000101"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0174215.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            78456..80078
                     /locus_tag="VW749_000102"
     CDS             78456..80078
                     /locus_tag="VW749_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0174216.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            80281..82239
                     /locus_tag="VW749_000103"
     CDS             80281..82239
                     /locus_tag="VW749_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0174217.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYFKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            82411..83346
                     /locus_tag="VW749_000104"
     CDS             82411..83346
                     /locus_tag="VW749_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174218.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSRSKGSSVALENLLAVPKEKFE"
     gene            83371..84093
                     /locus_tag="VW749_000105"
     CDS             83371..84093
                     /locus_tag="VW749_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0174219.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGYILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDADSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEGGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            84251..85345
                     /locus_tag="VW749_000106"
     CDS             84251..85345
                     /locus_tag="VW749_000106"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0174220.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            85353..86519
                     /locus_tag="VW749_000107"
     CDS             85353..86519
                     /locus_tag="VW749_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0174221.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVVTFAKR"
     gene            86612..89710
                     /locus_tag="VW749_000108"
     CDS             86612..89710
                     /locus_tag="VW749_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0174222.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVVVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLLQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            89758..90375
                     /locus_tag="VW749_000109"
     CDS             89758..90375
                     /locus_tag="VW749_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0174223.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVQPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            90386..91720
                     /locus_tag="VW749_000110"
     CDS             90386..91720
                     /locus_tag="VW749_000110"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0174224.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            91730..92194
                     /locus_tag="VW749_000111"
     CDS             91730..92194
                     /locus_tag="VW749_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174225.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            92191..92685
                     /locus_tag="VW749_000112"
     CDS             92191..92685
                     /locus_tag="VW749_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174226.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            92766..94421
                     /gene="mltG"
                     /locus_tag="VW749_000113"
     CDS             92766..94421
                     /gene="mltG"
                     /locus_tag="VW749_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0174227.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGSETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            94492..94974
                     /gene="greA"
                     /locus_tag="VW749_000114"
     CDS             94492..94974
                     /gene="greA"
                     /locus_tag="VW749_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0174228.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            95256..95654
                     /locus_tag="VW749_000115"
     CDS             95256..95654
                     /locus_tag="VW749_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174229.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            96075..97082
                     /locus_tag="VW749_000116"
                     /pseudo
     CDS             96075..97082
                     /locus_tag="VW749_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            97157..97357
                     /locus_tag="VW749_000117"
     CDS             97157..97357
                     /locus_tag="VW749_000117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0174230.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            97392..98108
                     /gene="atpB"
                     /locus_tag="VW749_000118"
     CDS             97392..98108
                     /gene="atpB"
                     /locus_tag="VW749_000118"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0174231.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            98122..98616
                     /gene="atpF"
                     /locus_tag="VW749_000119"
     CDS             98122..98616
                     /gene="atpF"
                     /locus_tag="VW749_000119"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0174232.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            98616..99152
                     /locus_tag="VW749_000120"
     CDS             98616..99152
                     /locus_tag="VW749_000120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0174233.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            99167..100672
                     /locus_tag="VW749_000121"
     CDS             99167..100672
                     /locus_tag="VW749_000121"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0174234.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            100688..101566
                     /locus_tag="VW749_000122"
     CDS             100688..101566
                     /locus_tag="VW749_000122"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0174235.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            101652..103058
                     /gene="atpD"
                     /locus_tag="VW749_000123"
     CDS             101652..103058
                     /gene="atpD"
                     /locus_tag="VW749_000123"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0174236.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            103069..103488
                     /locus_tag="VW749_000124"
     CDS             103069..103488
                     /locus_tag="VW749_000124"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0174237.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(103533..104546)
                     /locus_tag="VW749_000125"
     CDS             complement(103533..104546)
                     /locus_tag="VW749_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0174238.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            104690..105856
                     /locus_tag="VW749_000126"
     CDS             104690..105856
                     /locus_tag="VW749_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0174239.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            105846..107075
                     /locus_tag="VW749_000127"
     CDS             105846..107075
                     /locus_tag="VW749_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0174240.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            107221..107862
                     /locus_tag="VW749_000128"
     CDS             107221..107862
                     /locus_tag="VW749_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0174241.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            107872..108501
                     /locus_tag="VW749_000129"
     CDS             107872..108501
                     /locus_tag="VW749_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0174242.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            108514..109350
                     /locus_tag="VW749_000130"
     CDS             108514..109350
                     /locus_tag="VW749_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0174243.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(109629..109976)
                     /locus_tag="VW749_000131"
     CDS             complement(109629..109976)
                     /locus_tag="VW749_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0174244.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(110087..111805)
                     /locus_tag="VW749_000132"
     CDS             complement(110087..111805)
                     /locus_tag="VW749_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0174245.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            112039..112364
                     /locus_tag="VW749_000133"
                     /pseudo
     CDS             112039..112364
                     /locus_tag="VW749_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            112437..112883
                     /locus_tag="VW749_000134"
     CDS             112437..112883
                     /locus_tag="VW749_000134"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174246.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            113223..113477
                     /locus_tag="VW749_000135"
     CDS             113223..113477
                     /locus_tag="VW749_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174247.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            113588..114694
                     /locus_tag="VW749_000136"
     CDS             113588..114694
                     /locus_tag="VW749_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0174248.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            114652..115260
                     /locus_tag="VW749_000137"
     CDS             114652..115260
                     /locus_tag="VW749_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0174249.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            115484..116353
                     /locus_tag="VW749_000138"
     CDS             115484..116353
                     /locus_tag="VW749_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0174250.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            117264..118460
                     /gene="tuf"
                     /locus_tag="VW749_000139"
     CDS             117264..118460
                     /gene="tuf"
                     /locus_tag="VW749_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0174251.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT        36743 a        21665 c        26725 g        33845 t
ORIGIN      
        1 atttgaaaga gggatgtgat agtagcaccc tctttttctt tgttttatga tagttcatcc
       61 tcgagtaaat tcaagatctt gctcggaaat gaagcttata tagtagattg aatatagaca
      121 aagaccttgt gattggtaaa acattttaga aattcattta cctttcctaa tcgacttggt
      181 ttcatcttat ttcaatctat tatagtattg gggaatttct tcaaaccaca tcagcttggt
      241 cagttctacc tgcgacctca aaacttgtgc tttggtcaag ctgggtttag tttcctagtt
      301 tgctgatgga tttccattga ctataagcat ccaaccctct tttttgtctt ctaaagaatt
      361 cttaaattat cagtctattg caacttttct catataagtt ctttgtcttg ctattggttt
      421 tccttagtag tatactaagg tagtaatcat taagaagtgg ttacaaaaaa taatgaatga
      481 ggtaaagaaa atggtagaat tgaaaaaaga agcagtaaaa gacgtaacat cattgacaaa
      541 agcagcgcca gtagcattgg caaaaacaaa ggaagtcttg aaccaagctg ttgctgattt
      601 gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc gtggtttcct
      661 tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gacggtcaat tggatgaaat
      721 cagcgaacgc ttgattacac tcggtggaag cccattctct acattgacag agttccttca
      781 aaatagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa gcttggaacg
      841 tgttcttgtt atctaccgtt acttgtcaga acttttccaa aaaggtttgg atgtcactga
      901 tgaagaaggt gacgatgtaa caaacggtat ctttgcaggc gctaaaactg aaacagataa
      961 aacaatttgg atgcttgcag ccgaacttgg acaagcacct ggtttgtaag aaataaggaa
     1021 acatagataa atctgtagga aatttcttac agattttttc tattttgtaa gctattccaa
     1081 accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg atggaagcat
     1141 gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg gtaaggaaaa
     1201 tcgtctgcct tggcatttgc cagcagaatt gcagcacttt aaagaaacaa ctctgaatca
     1261 tgctatcttg atggggcgtg tgacctttga tgggatgggg cgtcgcttgc ttccaaaacg
     1321 ggaaaccctg attttgacgc gtaatccgga agaaaagata gatggggttg ctacttttca
     1381 ggacgtccag tctgttcttg actggtatca ggatcaagaa aagaatctct acattatcgg
     1441 tgggaagcaa atttttcagg cttttgaacc ttaccttgat gaagtgattg tcactcacat
     1501 tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt ctctttttga
     1561 gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt ttaccatcca
     1621 ataccgcaag agaaaggaag tctaatggaa cggagtttat ttggtctatt cacggctttt
     1681 ctgtgtttca tctgctttct ggcaggagca caggcttttc gtaaaaagcg ttacgggctt
     1741 tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca tgctttttac
     1801 atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt ctacaaatag
     1861 aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag aagtacaaaa
     1921 aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag ctcaggaaat
     1981 cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc caaaaccaat
     2041 tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca agcgtgcctt
     2101 ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac gcgaagagtc
     2161 agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg gttcagggaa
     2221 aactttcctt gcccagacct tggctaagag cttgaatgtg ccttttgcta ttgcggatgc
     2281 gacagctctg acggaggctg gttatgtggg tgaggacgtg gaaaatatcc tcctcaaact
     2341 cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct atgtggatga
     2401 aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg tttctggtga
     2461 aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg tgccgcctca
     2521 aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa atatcctctt
     2581 catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc tgggtgaaaa
     2641 agtcatcgga tttggtcaaa ataataaggc gattgacgaa aacagctcat atatgcaaga
     2701 aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg gacgcttgcc
     2761 tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct tgaaagagcc
     2821 aagaaatgcc ttggtgaaac aataccaaac tttgctttct tatgatgatg ttgagttgga
     2881 atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga agacaggggc
     2941 gcgtggactt cgctccatta tcgaagaaac catgctagat gttatgtttg aggtgccgag
     3001 tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa cggataaacc
     3061 gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc tgaaatcttg
     3121 ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat tgccctagca
     3181 gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg taagaatctc
     3241 gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa cattgatgac
     3301 aagatgcgct ttgtggatgt gcctggttat ggctatgctc gtgtttctaa aaaggaacgt
     3361 gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct ccgtgcggtt
     3421 gtcagtctag ttgaccttcg tcatgacccg tcagcagatg atgtgcagat gtacgaattt
     3481 ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa gattcctcgt
     3541 ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga cccgagtgac
     3601 gatttcatcc tcttttcatc tgtcagcaag gcagggatgg atgaggcttg ggatgcaatc
     3661 ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata aggccccaaa
     3721 ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg ctagcggtca
     3781 agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag aacagacaga
     3841 gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact ttgaccatgt
     3901 tgtcaaaaca acttgcttct tgagcgatat gaacgacttt gttcctttta atgaggttta
     3961 ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag ctcgtcttcc
     4021 tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta gttgaagttt
     4081 ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac aatttcactt
     4141 ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt ccttcgagga
     4201 tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt ttttgcagct
     4261 ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc gtagccgttc
     4321 tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg gtttggattt
     4381 caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca aggaaaccag
     4441 acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt tggaacgtga
     4501 actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg aactcactcc
     4561 acgtgagctg cgcaaaaccc ttgcagagca gttttcagac caagaacaag cccagtcttt
     4621 ccgtatcgaa gtcatgtctt tcggatttaa gtatggaatc ccgattgatg cggacttggt
     4681 ctttgatgtc cgtttcttgc caaatcccta ttatctacca gaactgagaa accaaacggg
     4741 tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag acttttatca
     4801 acatttattg gccttgattg agccgattct gccaagttac caaaaggaag gtaagtccgt
     4861 tttgaccatt gccatgggat gtacgggtgg acaacaccgt agtgtggcat ttgctaaacg
     4921 cttggcgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg acaaagaccg
     4981 cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat tggtggaggg
     5041 actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat cgcagctatc
     5101 gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat gcaacagttg
     5161 acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc taagttttat
     5221 gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg ccatccattg
     5281 ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa tgccatgcag
     5341 ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga ccatcctttg
     5401 acccttcatg cagtctttca ggatgggaca gaagtggctg gagagagtca tattgtagac
     5461 catcgaggca taattgacaa tgtctatgtg accaatgccc taaacgatga tacgcctctg
     5521 gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct agggccaggt
     5581 tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg ggctcttttg
     5641 gaaactaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg ggagacggaa
     5701 cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg cccttttatc
     5761 gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc caaccgtttt
     5821 gatgaatact tggtgcaagt ggaacacgat tttgtaggtc tttgtaagca agtttcgcgc
     5881 gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga tggagatttg
     5941 attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca gtagcagtaa
     6001 aagaagaaat cctgggccaa caccatctga gctggcatga attatctgcc attatcaaaa
     6061 tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg acagaaaatg
     6121 ccaaactggc ccgtcacctc tatgagtcct ttctccattt ctatgaaatc aaatctgaaa
     6181 ttcgtcacca ccaacggagc aatcttcgca agaatcgcgt ctataccgtt tttacagatg
     6241 aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt ggcctggaaa
     6301 caggtattga tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat ctctgtggcg
     6361 ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag ttggaaatca
     6421 gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag tttttactgg
     6481 atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga gcagaagaca
     6541 ttatggactt cttgatagta ataggagcca tgcaggcacg tgatgatttt gagcgggtta
     6601 agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag acagctaata
     6661 tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa atcaaagata
     6721 tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg aggattcagc
     6781 acccagacta ctctatccag cagttagcag atagtctcag cacccctctg accaaaagtg
     6841 gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa cgatataaag
     6901 caaccccttg aattatcaat atcttcaagg ggttttgttg tgttatgaaa tcaaaaaggg
     6961 gcaatcaagg ggcagaatta aaaaatagta tctaatttat tgaccagttt atcctccata
     7021 tcctcagtag tatgagaata gatttccaaa gtcatttttg catttgagtg cccaactcga
     7081 tccattattg attttattgg gaggtcagac tctgctaaaa acgaaatatg agaatgccta
     7141 aaaatatggc tagataagtt tttttctatt ttggcctgtt ttccatattt ttttaatatc
     7201 tgtatgaagc aagctattgt tgtaggttga ttccattttt caaaacagaa aatataatca
     7261 tcgcttgaca atggctggaa acgttcgcta agtcgtacta tttgtctttg aatagcttct
     7321 atgacactct ctgatacttt gattgtccgt attgaatttg tagtctttgg tagcgtcttg
     7381 attttgttta ctgaatcaaa attacctgtg atctcaattt tgttgttttc gaagtctata
     7441 ttcttcagtt gtaaggcagt taactcacca tatctcatac cagttaatgt cagcacaaga
     7501 accatatcag cgtacttttg gtgatattct cgacgattaa ggacatcgac aagtgctttt
     7561 atttcttgca tggtgagaaa gttgttacgc tttttttcca gttcttctaa agtctttggt
     7621 ttttgaggaa tcgtagtata atcgacctcg ttgttttcaa tgtaagagta ttgaacagcg
     7681 taattaaaga tacctctgag cctatgccgt acttttttag ctgtaatata tccgttgctt
     7741 tcaataattt tttcaatagc ctcttgaaga aaacgcctgt caagattagc aagtatggta
     7801 tcggatggta tgacttcctt catcttctta tcaactgatt tacaattatg ttttgttgat
     7861 tcctttactg tttgcgccca tgatttatag aaaaggttat agatttcttc aaatgtaatg
     7921 ctttctactt gttttgtgct gagtttttta tttatcttct cttgtaacaa gatagcagct
     7981 tgatttcttg cctggggagt tttcttctcc atggttactg aaactttttt taatttctca
     8041 gtatatggat ctttatatcg ctcaaaatat ttaaatttgc catttggcaa ttcttccatc
     8101 cacattgcgt ttacctcact tttttgttaa aatgggtaca agaaaactac ctttttaatg
     8161 gttgtttcct atacatgatt tcctcacact ctccttggcc aaaatttgag tgtggggatt
     8221 ttttggttgc tatctcgtca gataataaaa taaggtgtac ctcttagaag tacaccagac
     8281 gattttatcc ttgacgaaca aggctttttt acattcttag tgtatttctt tttttaattt
     8341 ctgtcaagca gttatttcct aaatggaaat agttggtttt aatttatact tttggttcat
     8401 tacggtgcca atcattagga aaacctaaag actggttgat tacattgatg tctatagaag
     8461 gcagcttttt ctctagtttg ataacttttt ttctaagagt attccacaaa atgttgaatg
     8521 ctgctttact aataaagcat tgaaggctaa taattgttga atatacagtt tttctactgt
     8581 catctcccat caagatctct ttgttatgaa tcgtttccca aaacgtacta ttagaacggc
     8641 atctgaagtt taataagcga ttattgtgag cgcatttgtt tcgtacctcg ttaatatttt
     8701 ttagaaaaga tatcaaggtt tctggtggga aaacatcgtt aaagtcaggt atgtttgtgc
     8761 ttataaaact tactaaatcc cgtgcgattt cattttggag tgaattaggc aggttttcaa
     8821 taatcgtgcg taaatctcca aactctagat aatcagttag tacccagatt gggacatctg
     8881 aatgagtatg tgcgtagtgg tgaattgaat ttcctctgta tcgcttgttt gtgtttatga
     8941 ttttggatag ttttgataca ataaatccca cgtctaatat tttattatct gcataagaat
     9001 tggtgtttaa ataagcgtat ttttgactgg ggtaagcttc ggcgaatctg tgagcagtga
     9061 ttgacttgat atggtgttca gcttcaagaa tagcttgcaa aatggctcgt tttacatctt
     9121 tgtcaaatgt atagagactt gaaacttcgt caaatgtgac gccgtcaata taagtgtcag
     9181 taccagggtg ttgaaaaaac ttactgtatc cattgataat attgtagtaa ttgttactta
     9241 gcaggtactt agctgcttta gattcatctg taatggataa ccctctgatt tttagtgttg
     9301 cgatttgttc ctcgattgtt ttaaatggct tcaaaaaaac tcccccattc taatttagaa
     9361 tgaaggagtt tccccgtatc ggtccccgta gagatcccga cgctttttct ctaatgaatt
     9421 cattctaaat gattttttta aaaaagtcaa ctgtttttta atatttttaa aaaataattt
     9481 ttttattccc ctctatacac cccgactact gcataaatct tgatgtgtgt gtcttcggct
     9541 ggtgggaagt ctaggatgat gtcttcgtac ttgtcattga gtgacactag gcgtaagcgt
     9601 ccgttttcgg tatatatctt cttgaagtaa gaacggtctc catatgcgat aattgctaaa
     9661 tctccgttgt aggtagtcag tcctttgtct actaaataga gaatgtctcc gtcttggtag
     9721 tcgggttgca tggagtctcc actgaccttg gtcgcaatat cgtggcgtgg tggtcgctcg
     9781 tcaacctcta tagtctctct gtctgtatcg tcgtacccaa atccatagtt aaatccagaa
     9841 gctgctgccg tctcagatac aacctcaact tggtacaagc tgataacttc cgatacttcg
     9901 tttatcttcg tttcttcttc gttttggctc tccagaagct cctcagaggt ccgtagcacg
     9961 attttttgat tgggtggggt taattgcact accttatcca ttatctgctg tgtgagcgaa
    10021 tctggagcgt ctggcagtga gttggtggat tcttctttaa aagtagtatc tatatctgat
    10081 tttttaacac cgaaataatc agccagtttt tggataacac caaaagaagg agcgcttctt
    10141 aacttcatat agtctgtcat agtacttgct gtaattccaa cttctttagc caactctttt
    10201 tgggtgatgc cacgttgctt tctaaagtgt gtaatatttt cagcaataat ttgcattcgt
    10261 tttttttcgt ccatttacga ttacctcgta ttttttataa ttacattata tatcattttt
    10321 gaatgataaa caatcaaaaa tacgaaaaaa tcctattttt ttgataaaaa ctattgacaa
    10381 tacgaaaaaa tcgtattata attaaatcaa gcttaaggaa aaggaggtaa ggcaaatgaa
    10441 cgaactagaa agaacagccc tcaatgagat attgaggact gtgacatata tagctgagaa
    10501 gttggatgaa gtagattcta agatttcttt gaacgattca caagctcttg agcatcaagg
    10561 aaattgagtt tcatttccat gtagtgaata actccgtgta ggtagttctt taggtctgta
    10621 aaacctttat caggattatt tctatagtaa tgaccttcgt cgttaccgat ataagcagat
    10681 gcaagcgcaa atgttttaag gtcttcatcc ttgatatatt tttcaataac ttgttttaat
    10741 gacattttaa tgattttatc ttcatcatca ggatttgtaa caatggagaa atctttaaca
    10801 aagaactcaa gcgccttacg gtatccaata cctgcaatgt ggtctagttg ttcgtgttca
    10861 gctttcagtg cttggacata gatttgctta ccaattggag aaactatctc tacatcgtca
    10921 gatataggta tatcgctcgg aagattaggg attactttga tatgttcaat ttcgtatttt
    10981 tcggtatagt cattgattaa aaatcttgta gctataaact cctctgtcca aaagtgctta
    11041 caacctaagc atctacatgt taatactaag cttgttttat tttctccaag agaaaaataa
    11101 gaagagttca caagatctgg attggttggt tttttacaat ttgggcaaat gtcttcaacg
    11161 gttacaggcc tagaaacaga agaatttact ttcactcgaa atatcataag atttctccaa
    11221 tcgttttatt ttgattatac catatttgaa agggggtgag gaaatgagac caagacgata
    11281 tccgtatagt gggaaaaaag agtccacctt cgtaaaggca gaccctgagt taatgttgaa
    11341 tatcaataag attgatgttg gaaatataca agcgaaaaat atatttggaa aaatttaagg
    11401 agtaggagga tggatgaaag aaaatataga acatcttcat gaacgcataa agcattttca
    11461 gtcattgatt gcttatatgt ctgagcatga gaaaaagtat tatttagaaa aagattggtt
    11521 cgataaccca accctaattt ctatagaaga cgcaaaaaaa gaagtagaac tactttaaca
    11581 gaaaggaggt aggaacgtgc agtggacttt agaagctatg agaatcaaca aaggacttac
    11641 tcaagcagag ttggcagaaa aatttgaagt ttcaagtcaa acaattgcta gattagaaaa
    11701 agatagctct gatatcggtt atcagctatt gaaaaaatac atgttttttt tcaatgtgaa
    11761 attcgatgat atttttttag ggaaaaaata cgaaaatttc gtaaataact agaaacaaaa
    11821 aaataagaag gaggaacaca tagatggaaa gcgttcttga aagcttgaaa caagaaaaag
    11881 accacctcga aaaaatcatt aaggtagtta cctctggtgg taaatttctg agattgccgt
    11941 atcaaaaaaa gtcacgctcg attagtgaga atctgaaatt gatttctcaa aatcttgata
    12001 aattgagcga gcaagttcaa caaaccacga atcagcattc atgatttcaa gatgacgaaa
    12061 gaaacctgtt ttgatttcca gtttgatatc atgttacagc gactcgataa agcgattagt
    12121 gattaaattt ttgagatgta agtttttttc atgtcaaact ttttcatgtc aaatttttta
    12181 cactaataaa tattaactaa caacaagtat taaaagacaa ccagtcctac ttctctaaat
    12241 aaaagagagg gtagaaaaaa taaatacaaa ggaggtgagg aaatgagacc aagacgatat
    12301 ccgtatagtg ggaaaaaaga gtccaccttt gtaaaggcag accctgagtt agttgaaaaa
    12361 cttttaagaa acactagttt tcttgagcgt ttacaaaaaa agcctatcaa ttttcagata
    12421 gactcagaag aatttaagcg tcttagctat gaagccattc atgatacttc tcaagtaact
    12481 caatagtagt tattacagaa gtcaaaccac tgaccttccc cagttgcaat ccgtctgtat
    12541 ggtcaatctg tttagtagct tcattagctt tagcagagat agcttgcata tcttcagctg
    12601 ttaaagattc tcgaaaatct ttaaaggatt tcataaaaac tcctcctttc tattggaatt
    12661 ttgactaaaa cggtgagagg tcctagtcga gattattata gcaatttagg aggatattac
    12721 atcggtcttg aggctgattt ttggaggcaa tattggaaga taaaatcata gaacttgctg
    12781 attacttcat cagcgaatct acaacgtaca gagaagcaaa aatagcgtgt gagaagctat
    12841 tgaaacaagt cagccacgag attgaactca gggcgatgga aagtaggaca gtatgaaaga
    12901 agcagtaaag gaatttctaa aattcaggag ccgatttaca aaaatagaat ggtttgaaat
    12961 caaccaagct gtcgaagctc gtttaaatca aaaagccgac cagttgaaac tggacgacgt
    13021 agatttagaa atcatttcta gcagactaga aaaagttatc tagaaacgat ttgaatgaac
    13081 attggatgga tacgatagtc agcgccacga tagtgaatgt agatataatc ctgatggtac
    13141 atcgagtttg cttcaggttt agaaattggt gagtagagtt ctgcattttc ttcccaccaa
    13201 atgtaaggac tagccatatt tggtcccatt acacaatcgt cgtcggctga taggttcacc
    13261 caatttccgc aaagacatgc gtgaatttca gtcataatat tacctccttt ctggtttcat
    13321 tatagcagaa aaggagatag caaaaaagca cctgacggaa atcaggcgca tacttaaata
    13381 ttcaacatga ttataacacg aaaggagcaa aaatggaagc agttgaaatt gtaagaatta
    13441 aagatgtgat tattgaaaaa gtctctgcta atgatgaaga gttaaaacgt atctttggat
    13501 gttcaaaacg acaagcagga gagcgaagaa gagaaatgca aaaactccct agtcagcaaa
    13561 aacatctttt ggatagtgga caacttgtaa cgattaaagg tttctatgaa tacttgcaat
    13621 atcgtggaac taaagcttgg aaaaaagaaa tggaaacaag caagaaaatg aggtcagcag
    13681 gatgaaccta ctatcaagaa tcaaaaacta tttttcggaa gaggtcaaag aaactaatct
    13741 cgactggaaa gaggtcgctt tagacctcaa tcaatcacta attgaaacac aggaaaaact
    13801 tcaagaagcg aatcaagaaa tcgcagactt gaagaaaatc gtagcaatct ataaagaaaa
    13861 ggagaaagaa aaacgatgga atatatttac ctggtaacaa tcgtaggaat tggactatgg
    13921 tcgctagtaa ataaactaga tgaccacgct gaaatgaaac aaaaagagcg ccagctgatg
    13981 gcaaacaatg tcgcacggat gaatctgaga aattcagata agcaatttac ttatgatgta
    14041 gaaccgcctg aagggttgaa ataaggagga gaaacatgac tcaagctgaa cgaattaggg
    14101 aatattatag agagcaccct gctgcctcat atgatgaagt ggctgaggtc gttggtacaa
    14161 caaatagtaa tgtgagagcg aacctggcca aagacatcaa ggcaggcaga tgcgttcgct
    14221 tggaagataa gtcatacgat tactcgcctt actataacca tacacaggca ctcactgagt
    14281 tggttgactg gaagaatgac aacagacgtg agtgggtgga tatgctgaca agagcagcag
    14341 agaaagaaac ggatagcaac gttatgcgtt tgttaatcaa agaagcaaat aaattgatga
    14401 aagaggtgac taagtagatg gtacgaaata aaataggtga tttaactaac acgctcttcg
    14461 ctcaattaga gactctggat gatagggatc ttacagcaga tgaattaaaa gtagaattac
    14521 accgctcgaa acaaatggtc gcaatctcag gtcaaatctt acaagcaggt caattggcgc
    14581 tagatgctga aaaattcaaa gacaaggtag gtgaagtcaa tgccccgatc gctttgctgg
    14641 aaggatgagt acacggagta catgcatgaa atatgccctg gtcgtttaac tcctgaagta
    14701 accaggttgc tgaatgaaaa atttggtacg aattataaca agagtcaaat cggtggcgta
    14761 cgcaaacgtc tagggttagc agttggaaaa gtctatcaag gtcgattgct gacaaaggag
    14821 caacatgatt atcttgtatt gatccaaaaa aataagattt ctcgtaatgt cgcaaatgaa
    14881 atgaaccaaa aatttggctt atcgctaact gagaaacaga ttaagagtta tcggagaaat
    14941 aataatctac atagtggttt gacaggaaga ttcgagaaag gtcagactcc tcacaataag
    15001 gggaagaagt accccaatat gccaaaaaac ggcgggcagt tcaaaaaagg taatcgacct
    15061 ccgaattatg tacctgtcgg tactatcaac tacacaacaa acggttatcc aaaagaaaag
    15121 attggagaac ctaatcaatg ggttttgaaa caccgcaagg tttgggagga ccatcacggg
    15181 ctgataccaa aagggtactc aatcgttttt ctggacggtg ataaaacaaa ctatgatatt
    15241 tcaaatctgg catgtttatc taagaacgaa attgctagaa tgaatcaaaa tcatttattc
    15301 acgtccaacg ctgatttgac taaatcaggt attggactaa caaaacttac aaataaaatc
    15361 agagaggtag aaaaaaatgg ctagtttata cgaactaaca ggtcagttcc tgacaattta
    15421 ccaattggat atcgatgacg aaacaaaagc agacacgctt gaggccatcg attggcaaga
    15481 acaatttgaa cagaaagcag aaggatatgc ccatgttatc aagaatctag aagccgacgt
    15541 ggcaatgtac aaggctgagg aagagagctt caaagccaag aaacaggtgg cacagaaaaa
    15601 gctggattat gtcaaggata acattatggc agctatgaat gtcacggggc aaaccgaagt
    15661 taagagtggt gccctgatta taaaaattgc taagaatcca gaatcagtca aggtcaacga
    15721 agacgacctt ccgaaaaaat attttacaaa aaaagtgacg cttgcgccgg acaaaaaaac
    15781 actcaaagag ttgcttaaat ctggcaagaa agtcaaaggt gcggagcttg tccggacaga
    15841 aaagttggtg attaagtaat ggaattgatg aataaaacac gagtaacaga ttcactagca
    15901 gttgtgattg gaccagaatc gattgaagta cttgttactg aaggttttct atttgatgtt
    15961 gcgattcgtt ttgtaaaagt agacgaaaca aatcttgatc aaggaaatga aaagccagta
    16021 ttcactccgg aatacaagct ggtcacagtt gctaaataca aggaaaaacc tatctttgaa
    16081 tcggaggaag atattcgaaa atttgagaag caagcaaaag aagttaaatc gctatttgcc
    16141 tttgcaaagg taaataaaca aaattggttt aacactgccc tttatccagg agtgctgact
    16201 gagaaagttg gtgtttgatg aaaattttag ctattgatcc aagtagtaat aaaattgaaa
    16261 ccagcacaac aggagttgtc ttgttggata atgcaagatt agttgatagc tgggttgtct
    16321 cttatggtat gagaggtttc gctgattggt ttcacgaaat cggaacaaat cttgaattcg
    16381 atgtagttat tgttgaagaa tttaaggcga gggataacga caagtcgaaa gataatagcg
    16441 tggcagaaac catcgcctat atccaacttt gctatccagg tgccattctt caattcaatg
    16501 caggttacaa gtcggatatt ccaaacgatc ttttgaaaat cttagacctt tggaaatttg
    16561 aaaaaagtca tcatcaagat attcgagcag cagcaagact tggattattt tgggcaatga
    16621 gaaatgatat tgaagaagtg gttcatgata tcggaaaggt ggtgagtgag tatcacaata
    16681 acgctaagaa agtggcaagc tgaagcgatt aaaagaagtg aacatttatc taatggaatc
    16741 tttttagagg ctcttggggg cagaggcaaa actatctgtg cacttgctat tgcaaaacat
    16801 aaaaaagcta aaaaaatcat catcacaaac aatcgactag ctattctgaa tggttggata
    16861 gatgcagtca agtttatgaa ttttgataaa ggtgttgaga ttatcattca gacagataga
    16921 tatcttcaaa atcaagtcaa aaaggggcat aaattagatt gtgatgtgct gatagtagac
    16981 gaatggcaga atatgtcttc tgacaaacaa gtggccttat atcgcaaaat aaagcgaaaa
    17041 tacacgatag gtctttcagc gacaccaatt cggaaaaaag gacaaaattt ctatccgctt
    17101 gaaaaaacgg tatttggttg ggcaacccca aataataaat ttgactggca aaagactcat
    17161 ggaaaaatgg tctatgatcc atttagctat tcaaaagaga agtgggaaga ttttcaaaat
    17221 tatgaaagtt atatctcgag cttgcctaat ttcttccgct gggaagagat tgaaggaatt
    17281 gagaatgcag ttgagaataa cggttttgag attaagtttt accaaaagag agtcgcctct
    17341 ggcaatccag aaaaacttgc agaatttaga aaactaaatc ttgtaacagt ggacggcaaa
    17401 actgcaatgg ccaagcaatc gtttggaaga aagacctttg aacgctacct taatcaaaca
    17461 ggcgtagcag tcgattttcc aaaattaaag ccagtaaatg cggatacgcc attgatgtta
    17521 caacttgacg gtttaatcga acgagcacca cacgatatgt tgattgtcag taaatctaag
    17581 cagattgtca acgtcattag cgagcgccat cctgaaattg gaatctggac gggcgatatt
    17641 caagaaggac tttataagaa attcgtggtt gctactagtc aagtgttagg tgtcggagta
    17701 gacggcttgc aacacaaata ccaaactatt gtcgtattgg atccagtaga agaaggttct
    17761 ggagaatatg atgattatcg acaattgctc tggcgcataa caggaagtcg tcagcagcat
    17821 gatgtaaatg taattgaatt ttattataaa gaaagttaaa aaaagaggaa aacaaaatga
    17881 ataaaacaac tgaaatgatc gtatttcgta gccgtaaaac tggagaattt cttaattctt
    17941 acaaggacag aagttcttta gcatttgcag ctgacttttg cagcttggaa tattgtttga
    18001 agcttcctcg taaaaaatac gaagacaaca aaaagactta caaggctctt gctgcagctt
    18061 ttgactgtga aattgtcgca gttgaagcgg aatacaaatt gacctatccg aatggatcag
    18121 aagttgaacc tatcaagcgt gaccgttcat caattgagga catgattaag gatattattg
    18181 gaggggttct ctaatggcat ttacacttcc agcaaataaa ccacaagttc ctaaagatac
    18241 cccacgaaat tttttcatct acggcgaaac catgagcgga aagtcttatc ttgcaaatga
    18301 attcccaaat ccaatcgttt tgaacacaga cgggaatgca gaagctaaca ctgttccaag
    18361 cattcagctg atcaatgaaa aagatgacaa gggacgaatt accaattcag taattaagca
    18421 gcttggagat atcttgcttg ctctccagac acagaagcac tcttatgaaa cagtcgttat
    18481 tgatgtaatt gacgatgtta ttgaaatgat taagattgca gtttgtgatg aattaacccc
    18541 agttggtaaa cctcgcttga aatccttgtc ggaaattcca tacggcaaag gatacgactt
    18601 ctttaaccaa gctatcacag aattagtcat tgacctcaaa gcattgccaa tgaatgttat
    18661 ttacatcagc cgtcaggtat ctgaatatga tgacaatggc aatgccacca aagacaagcc
    18721 aagcttgaaa gataagtatg tcaatcttat caatggaaac tctgatttga tgatccacac
    18781 tgaaaaactc ggcaacaact acaaccgtga ggttgaccgc aagcgtaaga cctattatgc
    18841 ggaccaggtt gatgacaagg ccatcttgaa aatcttggca actatccgtg gggctgttga
    18901 gcctgcaaag ggcaagctag cccctaaaaa agaagcagct aagacaacta aaccagctaa
    18961 gaccgaaaaa acaaaagagg cacctaagaa agaagttgac tctgatgatg aactatttta
    19021 agaaataaag gagaatacac atgagcttac tagatatcgc aaaatcaatc aaaaaagagg
    19081 gctttgaccc acgcaaagac agcgccaacg gtcctgcacc aatcccagct ggtacttatc
    19141 cagtagtcct gaagaaagca accttcaacg tatcggacaa aggctgggaa agccttggtt
    19201 atcaatttga aatccgtggc ggtgattaca gtggacgctc tgaatttgca acatttggca
    19261 cactgactga atggaacggt aagaaccttg actgggcagt tgaacgcact atgaaattct
    19321 ttatcaaagc cttggtcctt gctggcgaca gtatgcaagg aaatgaagaa gacggtaaag
    19381 ccttggaaga ggctctacaa cgtaaggcag ttggctctta ctacaacctt gttatctctg
    19441 tgactaaggg gaaagatggc cgtgagttcc gaaactatga ccttgaagaa gaagaagcac
    19501 aaccgctgac tgaagctgat atcgatgaag atgacctccc tttctaaaaa atagcaagtt
    19561 ttgggtcatt gatgaaactg atgaaagatt aggaccattc aatacatttg aagaggctta
    19621 tcaatcgttg ttattttatt taaaaatgac tgaagatgaa tatcagtcaa actatacggc
    19681 ccaggaactt gtttatattt acaaagagga gaaaaaacca tgccgtcgat gaaagaatac
    19741 gcattacagt accaaaagtt agggttctca gtcattccaa tcaatcctaa aaacaagatg
    19801 cctttaatcg aatttgctga taaaccagcc atgactccat ctgagattga aaacttttgg
    19861 gacggctacc ctaatgcaaa cattgcccta aagactacca acttctttgt cattgatatt
    19921 gacaaacacg gcaaatcgaa cggttttgaa tcgctaaaaa aatggaaaca tctaaattta
    19981 atcgaaccga cactgcaagc taagacggct agtggcggta aacatctatt ctacttcaaa
    20041 cgagaagatg agccgatcac tcagatgatt ggattcttgc ctggtgttga tattaaggct
    20101 cacgaaaata attatgtgtt agtcgcaccc tctgccacag ataaagggca gtatgagtgg
    20161 gatctggaaa agtctaagga aggtggcacg atggtcactc cttcaaaata tttaatccag
    20221 tctataaaaa aacagtatgg cgaaactcac ggttataagt atgatggtaa ggacggtctt
    20281 agggatttag ttagacgttc acatactaga gaccgaacac agactacaga tctctttgaa
    20341 accatcgccc ttggttttgg tgatgaaggt ggacgaaatg acaaactagc aaaattcgta
    20401 ggtggtctct tatatcgtgc ggtcgacgat ggtgtagttg ttcaacttgc aagattagca
    20461 aatgcaaata gtccaacccc tttgcctgaa aaggaaatga tgcgtactat tgaaagtatg
    20521 attaaaaaag ataggaggtg attgtgattg gtaatgtagt aagtattgac tcacaaccta
    20581 agatgataac gactgccaag ggagacatca aggccaacag tccaagtaat gtgttgatgt
    20641 ctttcaaagc tgatgatcag ttgagtattt acctaaagca caacgatttt tcccaagagc
    20701 atgaactcct taaagatatc aagatcggca acactctttt taaaaaaggt gagctccctt
    20761 ctaactttga ttcagtcgta aaagtttact ttgaaagtgt gttaggtgtt gctttctcta
    20821 gccaggcgat gctggacggc atggaaactt ttttctcaga acgttcttac aatccagtca
    20881 ttgagtatat ggaaaaggct gctgaaaaat gggatggtcg taaacgaatt gaccgaatgc
    20941 ttcaggttta cctgggggct gaagatatcc ctttagtttc taaaatcgct caaatgtggc
    21001 tagttggtgc agttgctaaa gtttatgatc catacgttaa gtttgactat gttctggatc
    21061 tagtcggtgg acaaggagtt gggaaaacat ccctccttca aaaattgggt ggcgaatggt
    21121 atacggatgc cgtaacagat ttctctaata aagataatta cgacattatg ttaaagagtc
    21181 taatcgtcaa cgacgacgaa atggtggcca gtaatcggat gagctttgca gaaactaagg
    21241 cctttatttc taaaactagc ctacgttatc gtaaaccata catgaaacgc acagaagagt
    21301 ttgccaaaaa cttcatttta gctagaacta ctaaccaaac agaatacctc aaggacaaaa
    21361 ccggtgaacg tcgttttcta ccagttatgg cagatagtaa acggcaaaaa aaacatccaa
    21421 tggaaatcga gccagagaca attgaacaaa tctggggcga agccgttaca atctatcgtg
    21481 ctggtgctga tttgatgttt gatgaaaata cagaggatga actgaatatc taccgtgaac
    21541 agttcatgta tcgtgatgaa gttgaattac aagtgcttga atatcttgat atgcccgtcc
    21601 ctgaaaattg gcaaaactgg tctattcagc aacaacatca atacacaagt aaatatttcg
    21661 ataatagtag cgactttgat cctggaagca aaaaactaga taaggtctca actcgtgaaa
    21721 tgatgtacaa cttatttatg agaaattcga atgacaggaa gctgtcaacg aagattaaca
    21781 tgatcatgga taatcatcct gattggaaaa aaagtgtttt ccgggcagga ggtaaaagta
    21841 caaaagggtt cgtaagagtg aaagattcgg aaaaaactaa tcggtagcaa ttaaaaaatt
    21901 atcggtagtc atcggtagca gttgaggggg agatcggtag cattctaccg ataaaatagg
    21961 acatcggtag cacatcggta gcagtctaac cccttgatat tactgacttt tatttaatat
    22021 ttatatataa tgctactctt ctacctatat ttttaaaaaa agtatataaa ataatagtaa
    22081 taataaagaa agcctataga atagggattc ttgaaaaaaa ctttttactt tttagaattt
    22141 atcggtagca cggtagcagt ttagaaaaaa gaggtaaaaa tgtcatacac agtaacatta
    22201 ttttttgaca acatggtaga cgaaactcac ttttttaaga aagagagtga tgctgccaaa
    22261 tgcaaggctc agttagaaag caagtatcga gggaatcgaa tgtataaagt taagcaggag
    22321 aaattggaag aatgaataag caggaactga ttaaacgtat cgaggatttg ccttatacag
    22381 aggggcctat cgcagataca atcgaaatta atagaaattg gatattgaaa tcaattgaac
    22441 agctagccga atccgaaata ggtcacgcag atgaagctcc acgctacgta aagaacatac
    22501 tagcacgatt gcgagaattg ccattgcatg atagagagtt ttggttaaag gctatcatga
    22561 gcgaatttga acaggatttt agccatgcaa aatggcgaga gggctacgag caaggtaaaa
    22621 ttgagggtat ggttgaacgt gaaaaagtca tagttccgca gtgtgtggcg gaatatatag
    22681 aatttaaaaa gaaaaacaat tttcatgttt acggtgcaat gagagtaatt gaagatcatt
    22741 atgataagaa agttcctgat tggttttacg aaaataacat cgaaaaattc tgtcttgctt
    22801 ggcttgacgg ctacgaggtt gaaaaagaga agcggtattt tgttaagatt aaagggaata
    22861 ttaaagaaaa tatgttggtt tatggagaac ttttgaaaag gtatttcttt acaaaaagct
    22921 ttagtttaga cgatgttata tattcccaca cccgtaaaga actagaaaat gcaaaaatcg
    22981 gctgggtgtt tgattgtgaa gggtttgaga ttgaggaggt ggagtgatga gccttacgct
    23041 aaatagcaca attggagact tagttttggc aatcggagaa attatcgttg gttctgatgg
    23101 taaaaccact acagcgatac tggagatacc tgatcaaagc ttttacttag agattgagct
    23161 taaattgaag gaggaggtca taaattgaaa cgattcatag ctatctggat tctgctatct
    23221 gctggattga atatctggca gagtatctac attaaaaagt tagaagaaaa gcgccctatt
    23281 gtcgtctata aagctgataa cgcaggcgct gagatattcg gtaaagtcgt cgagaaagga
    23341 cggcatggca agctatacac gcttaccatt cgtgactacg gggtgttcgt ggttacgaag
    23401 gacgtgtatg agaaagtgaa agtaggggat gaggtgttac tctaatggat gatattttac
    23461 aagctttagc aaaaatgcta aatatgactg ttgatgaagt aagttctttg cttacaacat
    23521 ttaaagggaa tgcaccacag atttatgaaa tgttcgttaa agaaaagatg ttttatgatc
    23581 tcttcagtct ttttcaaatc atgtcaattg taatatttag tatttctgca gtagttttag
    23641 cagttttaac tctcatatat tttacatacg atggtggttt tgtttattcc tatgatatac
    23701 gtacaggaaa aaccgaggaa gaaattaaat tagaacgcat tgaacggaaa agaaaggact
    23761 taaaaatacc actaaaaatt agttgcattt catcaagcgc aagtttgata acattagtta
    23821 ttgcaattgt tttaaaagca actcttgcac ctaattatat attcatcgtg aatgagattt
    23881 taccaaaatt aacgaagaga taggagttat catgaacgca ctagaaaaag tcgaacaatg
    23941 gtttatcgac cgtgaaatca aagaccgaaa aggtcgctgg attgatggct cgtttgtcaa
    24001 agaggaggat ttggcatgat accgaaattt agagtgtggg taaaaatagg aaaacgtatg
    24061 gttttttcag atgacattct tgctattgac tacgaaaaca aagaaatagt gacacaacaa
    24121 gtttattttg agaatggttt accagacgat agagatatct attgttatga ttttgacgaa
    24181 atcgaactca tgcaatcaac aggactcaaa gacaagaacg gcaaggaaat ctttgaaggc
    24241 gatattgtac gaactactag atttttgggt agagctgacg aaattggcgg tttctatgag
    24301 tatgacaagg aatttatagg gattgttaag cagcttgagg gttcttgggt aattgatacg
    24361 ggcagtgacg cagtatgttt atggactgaa attgaagaaa atgaaatcat cggcaacatc
    24421 tatgaaaata aggagtttgg aggacgcaaa tgagaccttg taaatatcca tattcaggaa
    24481 gaagaaaaaa acaagaaacg ccgtcgccaa tattttctgc acgaccaatt tttgacgaag
    24541 ttccaattgt agaagaagtt aaggttgagt tcggagttga agctagtatg gggcgcatat
    24601 atccagaaac gttaatacat ttagatattt ctggatacgg aaatagagtg cattcagtac
    24661 atcgcttccc cggtatttta ctgagtgttg gtgagtcaat ccaactaaag atgcttttct
    24721 ataaaagact tagaaatttt actacagatc gtttcttgac gtttagagaa tctgattgga
    24781 agttctttat ccgggacctg gtcaacgaat ttaagcatta aaaaaagcca agacactctc
    24841 tgcctcagct aatagttctc gcaaagacta ttatatcaca aaggagacag agagtgaaca
    24901 aggctaaaga gctcttgaaa gagttgcagg atctggacat ggacatccaa agccgtatag
    24961 acgaaattaa cgagcttgag gcaggtttgc tctcaagccc taaatggtcc gaggttaaag
    25021 tccaaggtgg acagactaga aaagttgatg atgtctatac tcagttggta gtgatgaaag
    25081 aggctataga gcaggatact aaagaggtca ttaacagaaa acttgaatta ggtagaatga
    25141 tcaataggct taaaaatcca aagtacaggg cagtattaag aatgacttac atcaacaaag
    25201 gcaccgctga tagcgtttgt tatgatttga atatgagtcg tacaacctac tacaggttaa
    25261 aaaatgaggc ggtcttagct ttggaagaag ttatctaacc tcatagtgag cttatgggac
    25321 tttttggaac agcacggttc taaaaatctg ttagaatggt agtatcaaga attgaaaaga
    25381 gaggtctcag aattggtaga tggttacctg taatgtcagg gggctgtaat ggccttggag
    25441 gttcaagtcc tcccctctcc tttgagtgtt tgtgtcccag aatgagttaa atcttctggg
    25501 tggggattca catatcactc attaactcct atcactcatt aacttaaaaa tggttgcgga
    25561 agcgactgga cctcgcatga ttgcgtagct aattatattc cggataagtt ataagctaga
    25621 gggtttgatt ccctcagagg ttttaaagac tacaaaaaat aaaaaagaag tcaaaattta
    25681 atacgcacgc aaggtagtag tcgccttgca agaaggtcgc acatcgtgtg gctttttttg
    25741 attattcgaa gggtggtgat ggaaaattga gtggattgag aataaaacaa aagagatttg
    25801 cagatgagta catcatctca ggtaatgcga cggaagccta taagaaagca ggttatcgtg
    25861 tttctagtga tagagtggca ggcgttgaag gacataagtt actaaagaat cctaagatta
    25921 aaagctatat agatgaacga ctgaaacagc ttgattctga aaagattgcg gatcagcaag
    25981 aggtcttagg ttatctaact tcagtcatgc gaggagagac gcaagaacag accttgataa
    26041 gcattggaga actagggcag acgattacgg atatagatgt aggagctaaa gatagaatca
    26101 aggcggctga acttcttggt aaacggcata ggctttggac ggataaggta gaggcggatg
    26161 tttctggaac ggtggtgttt gcaaatgagt cagacatatc agattaaaca aaacgatatt
    26221 gtcgttgact tacctaagac agtaggagct ggatacggac agttctggcg ctcaagaagt
    26281 ctttatcgtg tagtcaaagg gtcccgtggt tcgaagaagt ccaagacaac cgctttgaat
    26341 tatgttatcc gtcttttgaa gtatccctgg gccaacttgc ttgttattcg tagatactcg
    26401 aataccaaca agcaatcaac ttatacggat tttaaatggg cgtgtaatgt gttgggtgtg
    26461 actcatttgt ttaaatttaa cgagtctttg cctgaaataa ccataaaagc gactggtcaa
    26521 aaaatcctat tccgtggttt ggatgatgaa ctcaaaatta catctattac agtcgatatc
    26581 ggtagtctgt gttgggcatg gttcgaggaa gcatatcaaa ttgagactga agacaagttc
    26641 agcacggttg ttgagtctat ccgtggtagc ttagatgtac ctgatttctt taaacaaatc
    26701 acagtcacat ttaacccgtg gaatgagagg cattggctca agcgtgtatt cttcgatgaa
    26761 gagacgagac gggctgacac attcgctact acaaccactt ataaatgcaa tgagtggctt
    26821 gatgaagtcg atatcaaacg ctatgaggat ttgtatcata cgaaccccag acgtgctaga
    26881 atcgtttgtg atggcgaatg gggagttgct gaaggtttaa tctacgaaaa cgtgactgtc
    26941 aaggatttca ataaagatga attactacaa gattcagcta ataaattatg tatcggtctt
    27001 gactttggtt ttactcatga tccaactgct ttgtgttgtt cgttgataaa tgacacgacg
    27061 aaagagattt atgtctttga tgaggcgtat aaagtcggat tgataaccaa agaagttgcg
    27121 aagatgataa aagacaaagg ttatcatcgc tcacaaatca ttgctgatag cgcagagtca
    27181 cggctgattg aagagctcag gtcagaacat ggcatatcta gaataaaaga gagtcggaaa
    27241 ggtaaggata gtattatggc aggcgtatcc aaattgcaag gatacgctat ttatgtgcat
    27301 ccagattgta aaaacatcat ggatgaattt tatagttact gctaccagcg agataaagaa
    27361 ggcaactggt tgaataaacc agaggataaa aacaaccact tgatggacgc tttgcgttac
    27421 agccttcaat gtatcgaagg tggaaaagca accgtccgca gacgttctga ttatggtcta
    27481 tagagaggaa agacatgtac caatatttaa cctatccacg ggatggatat gatgagggtt
    27541 ctttgaagaa agacctgatt tacaaattga taacgataca taacactgaa agctcacgct
    27601 tgaagaattt aaaaagctac tacatgggtg atcatgctat tttaaatcac aagagacgca
    27661 acgtgaacgc acccaattac aagacggtag ctaatcatgc caaggatatc gcagacacgg
    27721 ctacgggcta ttttatgggc aatcctatca agtataacaa tactgctgac ggtgatattg
    27781 atgaactact tacagccttt gatggtgctg agattgacca agtggatgcg cagaacgcac
    27841 taaatatggc tatctacggc cgtgcttacg agtacatcta tgctaaagag ggtatgactg
    27901 agttggattc aactagtatt gatccggaga atactttcat ggtctacgat gatagtattg
    27961 agcggaagcc tttgtttgcg gtctattact atgaagtaaa agacgatacg aaagacacta
    28021 ccaagcacca ggctgaggtc tttaccgaaa atctgcacta tcacatggtg ctgagaagta
    28081 cagattcagg aacaactcag agcgaggagg caacacctca caaccttggt caaatcccaa
    28141 ttatcgagta tcgcaataat cactttgcga ttggcgacta cgagcaacaa attagcttga
    28201 tagacgctta taattccttg atggggaatc gtgtcaatga taaggaacag gctgtagagt
    28261 ctatccttgt cttgtatggc acgcagttag cagacactcc agaagacgct aaggtagcaa
    28321 tgaagattct ttctgaagaa ggtcttttgg aattgccggg cgatagtgca agggctgagt
    28381 tcttgaagaa tacgctggac gaaagtgcta ctgaaatctt gcgtacagct cttaaagagg
    28441 acatctacac atttagccat gtgcctaatt tgactgatga gaatttcgca gggaatacat
    28501 caggcgtagc catggaattt aagctgatgg gccttgagat gattactaag accaaggaag
    28561 cgaactataa gcgaggattg cgtcagcgta ttgcgatttt tgctcattac ttaggcatga
    28621 agcagattgc tttagagtct cattcaatcg ttccacaatt cagtcgtggt ttgcctaaga
    28681 acttattaga aatctctcag attgtgaaca atttggaagg caaagtgacc aatagacagc
    28741 ttatttctct cttgccgttt gtggaagacc ctgacgctga gctggaagcc ttggaagaag
    28801 agaaaaagaa gaacatggaa gacatgccga tgttcaacaa agacaacacg aaacccgaag
    28861 acgaggtaga ggatgaagaa tcaggagtat tgggcgaaga ggaaagccaa tctgatttac
    28921 cagcagatgg acaaggccga aaagcaggca gaccagttcg ataaggtcta tcaggaagct
    28981 aagacttact tggataagga aatcaataag attttcgata aattccaacg tgattatggt
    29041 ctaagtcagg tagaagctag acaagtcttg aagaacatga aagacaagaa aaatctgaat
    29101 gaacttcgta aagtacttga agcgagaccg aatgacccga acatccaaag attactagct
    29161 gacttagaca gcccagctta ttctttccgc atgaagcgcc tagagcgttt gagcgacgat
    29221 ttagatcgta tgcgtgaatc tatctatcat tcggagaaga caggctcaga tgccttttat
    29281 agcgacctga tgaaggatag ttactacaag gctacctttg acctacaaca gcagacagga
    29341 ctagcatatg gcttttctgg gcttcctgag aacgagatta aacatctaca gtcttttagt
    29401 tgggtaggag atggaagtac gtactcaaca gacatctgga agaatacagg aaaacttact
    29461 tccagcataa aagatgaact cctcattagc ctcatgacag gcagagatac acgagaaact
    29521 gcacaagcaa ttgctgagag gttcaatgta ggtcagaacg atgcaaggcg tttggttcga
    29581 acagaatccg ccttttttca taaccagatg gagctactca gctatgaaga agcagacata
    29641 gaaaagtata tctttgtggc cgtcttagac aagcgtacat cacgcatttg tcaggagcat
    29701 gacaatcagg tctatgatag ggataaggct gtccctggtg tcaattgtcc gcctatgcac
    29761 ccttggtgta ggtctactac tgtcggatac gatgaggacg cagactacag caagttgaag
    29821 cgcagagcaa ggaatccaga gacaggtaaa gttgagtacg tgcctgccga tatgacttat
    29881 aaagagtggt atagcaagta tgtggatggt aatagagagt ctattaaacg taaagcgttt
    29941 gataaaacta ttaaagatgg tataatagta agtgtatcag ggactacaat tggacacact
    30001 ccgcctggca aaataggttt gcctaatagt gtagttcagc ataatgctac aaacggagat
    30061 gtccttggta gaacttacta tgatgctaga ggttttaaaa cgaaagatgt tcattttaca
    30121 aaccataaac aaccggcacg tcatccttat ggaaaaatcg gagaacatgc tcatgatttt
    30181 gtatttgatg atgaaggtaa gttcgttagt aggagtacta gggaattaac agacgatgaa
    30241 agaaaggaga atcaagatat attatggcga tattagatga tttacaagcg ttatatgata
    30301 atggatggga cgcttctttt aattataatg gtcaagtatg tggcattttc cctaattcta
    30361 tttatgatgt tgttgttatt attgcggacg acgaatatag agcatcttct tttgacgatt
    30421 tgatttcttt acagattgaa gggaaaactt taccggaaat catgaacgaa gttgaagtac
    30481 aatatggcta aagcacctag agagatctaa gtgctttttt agtacccaga aaggagacta
    30541 tccgtacgat tttcttgatt gtgaatttga agtaaaaaga atttcagtga tagcttgcga
    30601 tactatcctt atagaagcct aaaagaaagg aacagaaaaa tggaagaatg gaaagaaaga
    30661 tttaaaaaag aatactacga attgaaagaa cgattccaga agttagatat gatgattggg
    30721 aaatacgaaa aagggcaact agagtttgaa tctaaatgtc cgattgattc gttaaaaggt
    30781 cagcgttcaa ccatgtggaa ttatttaaga attctagaac aacgtgcaaa aattgaagaa
    30841 attaaactat aaaaattaac cgcatcgaaa tcgatgcggt tttcctatgc cctaaccgta
    30901 tggaatcccg tacggttttt atattgtcca aactgtaccg atgacaataa aagctgtgct
    30961 gttccgtcgc cggacgtaaa acgagattat cgagtggcga cgtaatcgct ggaggacaat
    31021 tatgtcagaa gaaatcaatg caactgtatc tactgaatca actgagactg tcgacactca
    31081 aggaaatgtt gattcagtgc aggaagaaaa gcacgaacga actttcactc gtgctgaaat
    31141 cggtaagatg ctatctgccg aacgctctaa atgggaagct gagcaagaag ccaaggaaaa
    31201 cgaagctaag aaacttgcca agatgaacgc tgacgagaaa caaaaatatc agttggatca
    31261 gcgtgagcaa gaactagctg accgtgagaa ggctattgct cgcaaggaat tgaccgcaga
    31321 agctaaagca atgctaagtg aacgtgactt acctgttgag ttagtaaatg tagttgattt
    31381 gacaagcgca gagacggtat cgcagtctgt cgctgtattg cagaaatcat gggagcaagc
    31441 cgtgcaaaaa ggcgttcaag aaaaactaaa aggcggagct ccaatgaaac aagcgccagt
    31501 cgatagtgac ggtatcacaa aagaagaatt tgctcgtatg ggttatcaga gtcgaaatga
    31561 gctctatcaa aagaacccag agctttataa gaaattgaaa ggataataga aaatgacagc
    31621 aggacaaact aaattagcca ctatggttaa tccagaagta atggcggata tggtagccgc
    31681 taaattacct aaattgatta aatttacacc gctagcgtat gtagagacaa agcttgaagg
    31741 tcaaccaggt agcactttaa cagtgccagc atgggagtat gcaggagacg ctactgaaat
    31801 tgaagaaggc caagcaatta cgccagacca attgactact aaaaagacta ctatgaccat
    31861 caaaaaagca ggtaaaggtt atgaaattac cgatgagtct cttttgtcag gtcttggtga
    31921 cccactaggt caagcgactt accagcttgg tttagctatt gccaacaaga tcgataatga
    31981 tttggtagcg gtagctaaaa ctgcaacaca acatattaca gaaactccaa caactcttga
    32041 ggcaatcgat aaagctctag atatctttga ggacgaagaa gatgcacagt atgttgctat
    32101 catcaaccct aaagatgcta ctaagctaaa aactgcagta gcaaaagaat ggattaaagg
    32161 ttcagagctt ggagcaaata tggttgtttc tggaaccttc ggtgaagttg atggtgtgca
    32221 aatcgtgcgc tctaaaaaag ttgatgaagg taaaggcttc cttgttaaag tgtcaccaag
    32281 tcaaactcag acagacgacg ctaacaaata tggagctttt gttatcttgc ttaaacgtga
    32341 tgtggctatc gaaacagacc gcgatatctt gaagaagact accgtaatca caggtgatga
    32401 acactacggc gtttaccttt acgaccctac acgagttgta aaattcggtg gcgcgtaaga
    32461 ggtgacgata tgagtttatt gctacgacgt cattatattc aagaagagca ggttaaccag
    32521 tattctgatt tagagaataa aactctagaa gagttgaagg atctagcgaa agaagcaggt
    32581 gtagcaggcg cttataagtt gacaaaagcc gaaattgtag aagttttgga ggaactaaaa
    32641 agtgaaattt aaaatcaaac aagatttcta tgattgggaa tcaaatgtga aacgactggc
    32701 aggagaggaa cttgagatta ctgaggagcg ctatgctgag ctggctgaca atattgccag
    32761 caacggtgtc actatctcag acgttcttga gaaaatcctc cctgaacctg agttcttaga
    32821 agaggattga tatgtctata gagttgctga agaaattaac aggcgaagaa gatactcagc
    32881 ttctcatgtt gctccaaacg agggctacaa atcttatctt gtcagagact aatcgcacat
    32941 ctttgacacc tgctttaagt cttttaatac ctgaggttgc tatcgaactc cacaaccgct
    33001 caggagcgga aggagagcat tctagaaccg agggtggtat agcagtagtc tacggagaaa
    33061 acggcctgtc tacggatctt ctacagcgaa tacgcatgca caggctagca agggtggcag
    33121 gtcatgtttt tgaagcagag tagactgaaa ccttatccaa tgcgacggtt tgaaaagact
    33181 gtcactgagg aaggtgtcgc gaaagaaggg tatgccaagg aagctgagac agtccgcctt
    33241 gaattgtggc cagctagtag caagctacaa tctgaattgt atggcgagcg tgtcaatgat
    33301 attttgaacg caaatgccaa caagtcagct actatcaaag taaaagatgg tgtgtgtatc
    33361 gatagtcaga cggaagtgac tcatagggtt atttctaaaa aggtctacac acatcatcaa
    33421 gttttggagt tagagcgtgt cagggctact aggggcagat aggcttatag ctaaatgtag
    33481 acgattggct agtaaaaaaa ctggcgagga tatcgtctta cgtgcggtgc acaatgctac
    33541 tataaaggtt gtccaagcag atgcaagaag actcgcacca gcgagagatg gagagcttat
    33601 aactagtatc aaaactaggg caaaaatgga cggagataag gctataggcg aagtttacac
    33661 caaccttaaa tacgctcctt atgttgagtt tggaacggga ccaataggac aagctagcca
    33721 ttctggtatt tctccagagg tcagcgtgac ttacaagtct agtccgtggt atgtacatga
    33781 agaccaaatc aatgtaggac cgtaccactt tcaaaaaatc ggggagttct acaagatgta
    33841 tggtcaacct gcccagcctt atctttatcc agctttgaga gacaatcaag agcgtgtgtc
    33901 taagaatatt tcgaattatg tccgtagaaa gataagagaa caaataaaat gattaatatc
    33961 aagcctgtta tttataaaga attgcaaaag gttgcagata atgtgaccga tacttatcct
    34021 agcgattggg agactttccc agtcgttatt tttttggaag aacaaaacaa gccgggtgat
    34081 tggtttgatg accaggaaca aaaatcctct atccgctaca aggtggatat ctttgatgat
    34141 actagcacta gtgagttagc tgttaaaatc aatcagattt ttgagtcttt aggtttgcga
    34201 agaactgact gccaagacgt gccagacccg tctcatttga gacataaggt catgcgtttt
    34261 gaaggtatcg tcgacttaca ctcagagctt gtttttcaat ttagaatgga gaattaaaca
    34321 tgttagcaaa tggaattacg ctttcttatg gcgaaacaaa agatagctat actaaacttg
    34381 ttggattgaa agaagtacca gagtttggta ttgaactcga aaaagtagaa aatactactc
    34441 ttgaagatac ggtgaagaag tacgagtttg gtattgggga cataggagaa cttgagtaca
    34501 agttctctta taataattca agcgcaactg ctccttatcg tgtattgcgt aaggcagcag
    34561 acgacaagaa gaaactctac tttgaacaag cttatccaga cggtactaag gtcatttttg
    34621 aaggccaagt atctgttaag cttggcggtg gcggtgtcaa tgccgttatc gatttcacac
    34681 ttaagattgc cttgcagtct aatcttacat ttactgatgg tattggaggt taattaaatg
    34741 gcgttaaaat acacaacttg gaaagttact gacgaaaaag agttgaagct acgtttgaca
    34801 tctcatcaag ctgcaactgt ggaagaaaaa atcggcatga acttgctgaa gattttcatg
    34861 cctgaagctg gcgaagagtt cactttaccg cctttgaaag ttatgttgtt gttagttcac
    34921 ggagccttgc agcagtatga acatgggtat tctcttgagg atgtctatga tttatacgat
    34981 gaatacgtgg acaatggcgg agaccaaaca accttcatga cagaggtgtt gatgccactc
    35041 tttgaagtat cgggttttac tccacgagga agcaaggaca agaaaacttc caagaagaaa
    35101 atgacagtag acaagtaatc ttaacggtaa ctcagattat tgagaggctt tatcctatgt
    35161 ttttggacat cgagggcaag cctcttgatt tttgggattt gacggtactt gaaatcagag
    35221 aaatgattga aagctataac cgtgtcaaaa tccaagagcg taaagaaaag attattgact
    35281 catacagact ttcgcagatg atatccaacc acgtttcttt attgttatcc aaagatgcca
    35341 aggcctttga gttctgggaa tatgcgcctg agttgtttgt agaagaacaa caagcagtag
    35401 aacaggaacg acagaaacaa gcacttttgt tgcataagga acggatgcgt gaatttgcag
    35461 agagacataa tcgaaaaagg aaggaggaag taaatggcaa ctcttgatga attgaaagtc
    35521 atgattgacg ctgagatagc gcctttcagg aagaagatga aagaagtcga gaatcaggtc
    35581 aaaggaacat ctgaccaagt gaaaaatgct actgccaaag ttcgtgaaca gtcgagctca
    35641 atcggtagtg cgtttggcaa gctggctaag ttcgctggtt ttgcaatcct tggtaagaaa
    35701 ttacttgatg ttgggatgta ttcaacgcag acggctcttg aagtatcagc gtctatgaac
    35761 caaatcaagc gacagatggg cgagagttcg caatctttct taaaatgggt taacgataat
    35821 gccaacgcta tgaatatggg tgtgggtgag gctaccaact acggtgcagt ctactcaaac
    35881 ttattttctg gatttatcaa agataccaac aagctaagcg cctataccgc taagatgttg
    35941 cagacatcgg cagttgttgc tgaaggttca gggcgcacga ttacagacgt tatggagcgg
    36001 attcgctcag gtttactagg gaacaccgaa gcgattgagg acctaggaat caacgtcaac
    36061 gtggctatga ttgagtccac tgaagccttt aagaagttcg caaacggaca gagctggcaa
    36121 cagttggatt accaaaccca gcaacaaatc cgccttatgg ctattctgga acaggctaca
    36181 gccaagtatg gggatacctt gtctaattct gtaaatggtc gtatcagcct atttaagtcg
    36241 ctgatgaagg acgcagcatt gaaccttggt aactctatgt taccgattat caatgccatt
    36301 atgcctgtct tgaactcttt tgctatggtc ttaaagaacg ttactgctaa actcgctgag
    36361 tttatcgctt tgatgttcaa caagaaagca acagtgaaag atggtgttgg tggagcagtt
    36421 ggagacatgg gtaacgccat gaaggatgct gcaggcggag caggagacct tgctgacgca
    36481 gtagacgacg ctggagattc agcaggagga cttgctgaca atcttggaga ctccgccaaa
    36541 aacgctaaga aggccgctaa agagttgcta ggtcttttgg gatttgatga gattaacatc
    36601 ttgcaaaaac caaaagatga cgacgcaggc gggtctggag gcggtggcaa aggtggtaaa
    36661 ggaaagggag gcggtggcgg acctttcaaa gacatcttgc cagaagtcga gttgaccgac
    36721 atggacaaca aattcaagag catttttgat ggtcttggag ataagctcaa agggttgttt
    36781 gacctcttca agaaaggttt tgatgcagca tttagaccag aaggtataga acgcattaag
    36841 actgccttag accaaatagc taagacaatg ggagaaatcg ccactgaccc aagggttgtg
    36901 aatgccttta accgaatggc tgagaaaatt gcttatgctt tagggcaagt gacaggctca
    36961 ataacaacta tcgggctagg tatcggtgtt ttccttgccg aaagtattgc aaatggcctt
    37021 ggaaggcaaa aagaacgcat taccagggcg ctagtcgctt tgtttgataa tattggtaac
    37081 atttccgagg cagtaggaaa catcgctcag gacttttcta gtactttcta cgacgtcatt
    37141 acctcaactg gtgcggttcg tatcggtagc gctattgtgt caactctgtt gagtttgaca
    37201 tctaccattg ttgaagttgg tagtaaatta gcaggaagtt tgtttaaagg ttttgaaaaa
    37261 gtcgttgtga caagcgctcc taaaatttca tcagtcttcc aaagtttatt agatactgtt
    37321 gcgcctgtat ttgagagcat tgaaaggtct gttaacaaat ttggcgatgg cttaagtcgt
    37381 gtttatgatg aacatgtagc ccctgctatt aactctattg ctaatgcttt taacggactg
    37441 attgatatca tacaaatcct ctgggagaat tcttggcaac cttttgctga gtttttatca
    37501 ggagtattcg gtgttagtat tgaaggaatt tcagatttat taggaggtgg ccttttagcc
    37561 actttgggac tattggcgga tgctattaag ttagtggcag atggtttcac cgttttttct
    37621 gactggtgta aagaaaacaa agaacctatc ttggctttga taacaacttg gcaaacgatt
    37681 aatttcttat catgggctga acaagccggg ggacttgcag gagcattcag cttgttaggt
    37741 agtaaggtct ctttgattgt tggagggatt aagaatctag gtcttgctat taaagcattg
    37801 acatttgata agttggtcag ttttggtgaa acaatctatt tgaacacctt atatgcaaaa
    37861 gattttgtgg tcaattcagg taaaacaatt gcacagctag gaaaaactgc tttagaactt
    37921 ggtaaatcag ctctagcatg gactgctcat gcagcgaaaa tgggattagc aaccgcggcg
    37981 gaatttgcac attctgttgc agcaggagtc gctacagctg caacatgggc ttttaatgca
    38041 gcgttagcag ttttgacaag tccaataaca tggattattg cagcaatcgc agctttgatt
    38101 gctatcggtg tcttgctcta ccaaaactgg gacactgttg ttgagtttgc taaaactgca
    38161 tggcaaggac tatgtgattt tattagtggt atttgtcgag ctattggcga atttttcagt
    38221 ggtctatgga caaaactaca agaaatcttt gagccgatag gtcaatggtt tggcgagaag
    38281 ttccagcaag catgggatgc cattgtcaac atcttctctg gtatcggaga gtggttctct
    38341 ggtgtattcc aaggtgcatg ggacgctatc gttaatatct tcactccaat cggctcatgg
    38401 tttggacaac gttgggcaga tgtgactagt gctttggcta atatcggggc atggtttact
    38461 gacatattcc aaaaagcatg gactggtcta acaaacatct ttagcaaact aggtttatgg
    38521 tttggcgaga gatgggcaga tgttacaagt gttcttgcga atgtatcttc ttggtttggg
    38581 aatatgttta ctagtgctta taatgcagtc aagaacgcgt ttagttcaat tggtggcttc
    38641 ttcagcggtg tatggtcaac ggttcaaagc atatttgtca atgctggaca aaaggttggt
    38701 agcgctgtag gtggagcgtt taagagtgcg gtcaatgcgg ttcttggaac gattgaaaat
    38761 gtagtcaatg acttcatcgg aatgattaat ggagttttag gcgttgtcag aaacttacct
    38821 ggtctaggat gggttggtag tgtaagcaca gttagcctcc ctcgtcttgc ccgtggtggt
    38881 atcgtcgata gtccaacaat cgccatgatt ggtgaagctg gtaaagaggc ggtcgtacca
    38941 cttgaaaata caggatttat ccaaacactt ggacgagtag tcagcagtgc ggtagtaaat
    39001 gccatggctg gtattagtcc acaaggtggt ttttctagcg acggcgacat cgttattcaa
    39061 atcgcaggcc atgagttcgg acgggtagct atccaagaaa tcaacaagga acatgaacga
    39121 gcaggtcaaa ccttgctcaa gatttaggag gttaaatggc acaattgaca atcaatgggg
    39181 tggctgtgaa gcctcccaaa tcttttcaag tcggtattca agatatcgat ggagagacag
    39241 ggcgtaatgc caatggcgac atggtgcgtg accgtatcac gaccaaacgc aaactagact
    39301 gtgaatgggg tatgatgact cagggagaaa taagtcagct tttacatgct gtatcatcta
    39361 aattttttga ggtatcttat ccagacccca tggatggcca agtcacaaag actttctatg
    39421 tcggtgatag gacagctcct agctatacct ttactgagaa gcttaaacct tggtctggcg
    39481 ctaaatttaa tctggtagag aggtaagaaa atggacgctt taactagacg acaatttgac
    39541 agagccatgt ttgccaagga aaggacgctg gctattcgtg ttggtgaata tgcttcacgg
    39601 gatatcaaag aggctagttt tgagtatggc tacatcaagg gcgatactta taagcctggt
    39661 ggaacctgcg ctggtagcgg taaaattacc tttaccagta tcattaccac gttcaataag
    39721 ctggataccc tgcaccctga gattggtcta ctggttgggg atacctacca gtgggtcaag
    39781 atgggggaat acttcatcaa cgatattgag attgaccgaa accgcaacac aaccacactt
    39841 gaacttatgg acggtatgtt taagctcaat cgtgagtacg tgacggattt gcatttccca
    39901 gctgaagtac gagaggttat tcaggaaatc tgcctgaaaa caggcattga gttagcgaat
    39961 gactatttcg gaatcagcgc tatgcgttac catatcgagc aagttcctga aggtaagaaa
    40021 ctttcgttca gggatatgct gagcgctatg actcagatga ttgggatgtc ttgcttcttc
    40081 aaccgagaag gaaagatgga aatccgtgat ttgaccgagt ccaacatcac gattaacgct
    40141 gacagttact tcttgcatgg attgaccaag agtgaaatcg agtatcagat agctggtatc
    40201 acttgtaaga cggataagaa gtctctgacg gtcggtatga caacaggtcg gtctttggaa
    40261 cttgataatg tcttcataac ccagagcgct ttaaatgact tgtattacaa actgaaaaac
    40321 ctaacttact atccgtataa tctcaactac caaggacatt tgttacttga ggttgggcag
    40381 tgggtaacca ttcagaccaa caagaaagag acttttaaag ttcctgtctt aagtcagagc
    40441 tttatcttta aaggtggtct gagaggtcgt atcagtgcag atagtaaggc tggaaacgat
    40501 acccagtatt cttacgaggg tacgattacc aagcagatta agcaacaaga tggctttgaa
    40561 gcgaaaatcc aagcgcagat tgaagcagca gataaagatt ttgaccaaaa ggtcgacaaa
    40621 atcaaaaaag actttaacga tcaagtagaa ctggccaaag ccagagctga agaagtcaag
    40681 agagaactgt ctgacactat caatcagcgc tttaatagct ttgacaacgg gccattgaaa
    40741 gaagctaagc gcaaggctga ggaagctttg cgaaatgctg gcgcaagtag ttctcttgct
    40801 caggaatcca agcggattgg gctggattct gttgctagac ttgaagcgtt taagtcgcag
    40861 actacgagcg cacaaacggc tctgtcgggt gacttggatg ttctaaaacg aactatcgca
    40921 aacgatattc gaccgaagca agcacaggct gaagctgaga ttgccaagca agttgaagca
    40981 cttagccgga ctaaaaatga actggatggc gcaagtaccc tgcttgcaca ggaagctaag
    41041 cggattgagc tggattctgt tgctagactt gaagcgttta agtcgcagac tacgagcgca
    41101 caaacggctc tgtcaggtga cttggatgtt ctaaaacgaa ctatcgcaaa cgatattcga
    41161 ccgaagcaag cacaggctga agctgagatt gccaagcaag ttgaagcact tagccggact
    41221 aaaaatgaac tggctggcgt gaagtcagcg caagcgacgt atgaggagac gacgactcgt
    41281 agactgtcag aactgaccaa cttggccaat ggtaaagcca gcaagtcaga actcacgcag
    41341 acagctgagg agctagctag tcggattgcg agtgtgcagg catccggtcg aaatctattc
    41401 ttgaactcac tattcaagca ggatatttca aaaacaggaa tttggacaac gagtacatat
    41461 acggctacta tcgatagcga aagtaagtat cttggatata acgctcttaa aattataggt
    41521 ctgaatccat ctggccgtga tggagggaat cccaaggtta cttatccagt tctgggtcaa
    41581 ttcgggaaag taattcccgg aagtacgact aatcaagatg taaccattag tttttatgct
    41641 aaggcaaata aaaatggaat aatgctaaga tctcgattag ggaatatcgg atataaaact
    41701 ggaaatgtga cattgtcgac agaaattaaa cgatatgttg tccatattcc aaaaggttgg
    41761 acaaacgaat ccaagcagac cacaaatgaa tggttgttca atttcaacca ggaaggaacc
    41821 gtttggattt ggatgccgaa gtttgaaata agcgatgtag atacttctta ttcagaagct
    41881 cctgaagata tagaaggtca gatttcaaca gttgaatcga cctttaaaca acgagtcaac
    41941 tcgctcgaag ctggtgtgaa tcgtctgact gaaggcctta gaaccaaagc cgatatcagc
    42001 gcactcaacg tgactgctga aaatatccgg caatctgtga agagtcttga gacagacacg
    42061 cagaacaagc taaatcagaa gttgagtcag gctgaatttg aggtgcgagc cggctctatc
    42121 cgtcaggaaa tcctgaacgc aaccaaggat aaggcagata agactttagt tgtatctgaa
    42181 gctgggaaat tgcgtgaaga attttcaaaa atgaaggtgg gaggccggaa tctatggata
    42241 aaatccaaga cggttggagc tgtaattgaa aaattacctg aaaaccatgt cacaggtcaa
    42301 aaagaatgtt ataggttaga gaacaactct actttaacgt tcaaccttga accagatttc
    42361 agctcaaggt tgtatcaaaa agttactttt agcgcttgga tcaagtacga aaatgtagtc
    42421 caaggtcgaa acttttggaa tgtatttaat tgcttcaaac attatctttt tagaaaaaat
    42481 agtgagaccg gagtacagag tggtccagat tatgctacgc ttggtatgta taaaggttcg
    42541 gcagattgga aatatattac attcacttat gactactctg aaaaaacaaa ttttgatcaa
    42601 ttgaagacat cattgcgatt caatcttgaa ggtgctacaa gcggtacagc ttgggtaaca
    42661 ggaatcaagg ttgaaatcgg tagtgtggcg acggactggt caccagcacc agaagacgga
    42721 gaaaatgagc ttttagtcgc taaaaccgag ttcaagagga cagctgatgg cctatctact
    42781 aagatggcag cagttgagag ctatgttggt caagacggtc agcgacagga agccctacag
    42841 cgctatactc gtgaggaaag cacgagacaa gcgacagcag tccgtgagct ggtcaatcgt
    42901 gatttcgttg gtaaggctac ttatcaagaa gatgttaagg gtatcaatca gaggattgaa
    42961 gctgttaaaa ctagtgcgaa taaagacatc gctagtcaaa tcgctagcta tcgtcaatct
    43021 gtagatggta agttcacgga tatttcaagt cagataacta cttataagca agatgtgggc
    43081 ggtcaaatca gtggtctatc aaatagactt acaagcagtg agcaaggaac cactactcag
    43141 atttcaaata tttcaaatcg gataaacagt aataagcaag gcacagataa tcagatttca
    43201 aatttaaaga ctcaggtcgc tacaaacaag gataatgctg aacgacaaat gggtagaata
    43261 tctgatcagg tttctgcaaa caaagcgaat gctgatagtc aatttgcgaa tgtgaccaat
    43321 caactagcgc gaaaagtaga gactactgac ttccagcgtg ttaaggaaac cagtaaactt
    43381 tacgagcgaa ttttgggcaa tactgaaaat ggaattgcgg ataaggttgc tcgcatggct
    43441 ctgactaatc aactgtttca ggttgaggtt gggaaatata gtgtaagcgg ccctaacctc
    43501 attaagaata gtgattttaa aaatgctacg aatgaatggg gctcaactca aaatttagga
    43561 agattggtta agcatagctt ttatcacaac gggcagaaag accttatgcg tttaagtaat
    43621 gcaactaaaa acgaaaactt tttgtatagt caccgtttta atcttgaacg aaatactgac
    43681 tatgtactga attttagagg atttaacaac agtgctctcg caagctatga tgtttatatt
    43741 ttgggacgaa gagcaggcga gagcgatgga ttcacaatcg ttaagaaagt tgttagcagc
    43801 aagaaactat ctacctctag atgcgaagat gtctcagtaa cttttaattc cggagaaatg
    43861 gataatgctt acattcgttt tgataacaat ggctcatcat caggaacagc tgatttgtat
    43921 attacagaag ttgacttgta caaaggttat aaacctagaa catggcaacc acatccagaa
    43981 gatgcagtcg cagatgcgaa taagaagctt gaagcaacgc aaacaaaaat gactcaacta
    44041 gctggctcat gggtagttga aaacatcaac tcggctggag atatcatctc tggaatcaat
    44101 cttggcgcca atggacataa ccgcttcgtt gggaaattga cccacatcac tggagagacc
    44161 ctgattgaca gagcagtcat caagtctgcc atggttgata agctgaaaac gggcaatttt
    44221 gaagctggtt cggtcacgac tacgatatta gacgctgaag cggtaactgc tgagaagttg
    44281 aaagttgacg atgcgcttat tagaaaatta actgcaaatg atgcttttat tgaccgactg
    44341 acatctaaac gtatcttctc tactaaggtt gagtccgtca tttctagttc aaccttccta
    44401 gaagcctatc aaggtcgaat tggtggattc acacttggtc aatttgacca gggtggcggt
    44461 cgctggattt caggtgtcaa tcagttctct gttggtatgg ggaatggtgc cgggcatgga
    44521 gtccggacag ccttctgggc gaactgggga aataattgga actatgccgg acctaaagca
    44581 tggaacgtca atactgatgg gaaaatgtac tgtaggaatg aagtcggttt ttatgatcaa
    44641 gtggattttt cgaattcatc gagagcaaac ttctatggga atactacttt ttctcgttct
    44701 cctgtgtttt caaatggtat cgaacttgga agtaaagatg tgcttggtga tggttggaat
    44761 cccaaaggcg gaaggaatgc ggttgtttgg tggaatcagg tcggtagcgg tagcgtgaag
    44821 tattggatgg aacaaaaatc agacagacgc ttaaaagaga acatcacaga tacagctgtg
    44881 aaagccttgg acaaaatcaa cagattaaga atggttgcat ttgatttcat cgaaaataag
    44941 aaacatgagg agattggtct aatagctcaa gaggctgaaa ccatcgttcc aagaattgtc
    45001 tcacgagatc ctgagaatcc agatggctat ctgcatattg actataccgc tttagttcct
    45061 tacttaatca aggctattca agaattaaat caaaaaatag aaaaaatgga gaaaacaata
    45121 gcatgaataa caacatgttg accaatatcg cactttaaag caattcagga gcttgctctt
    45181 gaaaatagaa aacgaacaca cagattggag aacttagaaa atgaacacag aacagcttaa
    45241 ccaagcctta caaatgacaa ttagtgaaat gtcaacaact tcaacaaatt cgatgattac
    45301 aaataatatc ttgagtattc agttggatga gcaaagggaa gggaatcaaa gacttcaagc
    45361 acgagtggat gagctggaag ctctgcttga tgaacaaact aaaccagcag acaaaggaga
    45421 atagacatgg cagaaacaaa tcaaaacaca gataacttac tagaccttac aaaaatcaca
    45481 gaaccatttg atcttgcgag tgctttgcgc tacatgaaag aaaatggaga gttcattcgt
    45541 tgcaagaatg taagcgatga cttctatatg tatcgtgatg ttcaaaaacg tcctgtgatc
    45601 gtaaatggcc gtcgccaact caaggatgtt gaaaccgttt gggcgttcaa ccagtggggt
    45661 ggtacaatcg caacaatcaa cgtcgccgtt ctgttgaatc atgaattcta tatcatgaaa
    45721 tttgatgcag agggcaatcc tgactggacg gatccaacgg taaaacctaa agaataggag
    45781 gtgtgtatgc caattgaaga agctgaaaaa atcgctcaaa gtcaggtagc ttgggcgatt
    45841 ttgtttatct tgcttttctt tattatcatt cgatatctta tcaagacttc ggacaagcga
    45901 gagaagaaga ttatggattt gcacgagcaa tcaaaggccg actctaatag acgagaagag
    45961 cgtttgatga ctcacctaga aaagaccact acagaattaa ccacaatcac tcacgcggtc
    46021 ggagacattc aaaaagaaat ggttcgcatg aacgaccgca tggaagaaat cgaaaaagga
    46081 gaataacaaa tgcaacaaat tactgaaatc attactaatg gagcaatcag catccttgtt
    46141 attttggctg gtatcgcagt caaggcagtc aaggactacc tggttcaaaa aggtggagaa
    46201 aagaccatca aaatcgttga aatcttggcc aaaaatgcag taaatgccgt tgagcaagta
    46261 gctgctgaaa ctggctacaa gggagatgaa aaactggcac aggctcgcgc taaagtccgt
    46321 gctgagctta caaaatacaa tattagcatg actgacaaag acttagacac cttcgtagag
    46381 tcagcagtga agcagatgaa tgacgcatgg aaaggacgat agggaatgga tatcgataga
    46441 aacagactac gtacaggctt gccacaggtt ggggtgcagc cttatcgaca agtacacgcc
    46501 cattcaacag gcaaccgtaa ctcaaccgta cagaatgaag cggattatca ctggcggaaa
    46561 gacccagaat taggtttttt ctcgcacgtt gttgggaacg gtcgcatcat gcaggtagga
    46621 cctgtgaaca acggaagttg ggatgttggg ggcggttgga atgctgagag ttacgcagcg
    46681 gttgaactga ttgaaagcca ttcaactaaa gaagagttca tgacggacta ccgcctctat
    46741 atcgaattgc tacgcaatct agcggacgaa gcaggcttgc cgaagactct tgatacagac
    46801 gacttggcag gtatcaagac gcatgaatac tgtaccaata accaaccaaa caaccactca
    46861 gaccatgtgg atccatatcc atatcttgct aaatggggca ttagccgtga acagtttaag
    46921 caagacatcg aaaacggctt gagagctgca acaggctggc agaaaaatgg cactggctac
    46981 tggtacgtac actcagacgg ctcttatcca aaagataagt ttgagaaaat caacggtacc
    47041 tggtattatt tcgatggctc aggctatatg ctttcagacc gctggaagaa gcacacagac
    47101 ggtaattggt actactttga ccaatcaggc gaaatggcca caggctggaa gaaaatcgct
    47161 gagaagtggt actattttga tgtagaaggt gccatgaaga caggctgggt caagtacaag
    47221 aacacttggt actacttaga cgctaaagaa ggtgctatgg tatcaaacgc cttcgtccag
    47281 tccgcagacg gaacaggctg gtactacctc aaaccagacg gaacactggc agataagcca
    47341 gacttcacag tagagccaga tggcttgatt acagttaaat aaatagaaag gaaactttct
    47401 aaattgttct ttcaccgcag gctcaggctt gcggtttttt tgttttaaaa aaggggcaaa
    47461 aaaggggcaa aagtgtcgta aatctctgta aaatgatgta aaaacattta tttaaaagct
    47521 caaaatatag ctgttttaaa aggtattgta agatatagta aaacgatgta aaggtatttt
    47581 taaatgcgga tgaattataa aaccacgaat cctatgtgac tcgtggttct tttttataaa
    47641 ctggtagagt gttttggttg tactttttgt tcagggtcaa tgtagttgat agcgttgttg
    47701 acagcagttg gagcttcccc tagacctgtc gcaatcagat caatttttcc gtcatagtag
    47761 cagcagtcac cgatagcata gatacctgct tggctggatt cttgtttgct gttgacgata
    47821 atcttgtgac ggttgaggtc gagcccccag tttttaaggt taccgacaga agatttgaaa
    47881 ccatagttga caaagaggtg gtctaggtca atggtttcag tttcatcaga tttgactttt
    47941 gtgatttcaa gtttatcaag cgtttttcca tctccaagga gttggctagg gacgaatggt
    48001 gtcttgatgg ttacagatga ttcttgcaag gcttgaacac tgtgttccaa ggcacggaaa
    48061 ttatctctgc ggtgaacaag ggtagttggt gcgatttttt caaaagccaa agtccaatcc
    48121 acagccgagt ctcccccgcc aagaatcgtc actttcttac cagcgtattg ctgaatgtta
    48181 gaaacgtggt agtggatatt ttcatagccc tcaacacttt caagttccag cggacgtggt
    48241 ttgaaggcac cgccacccat agcgatgata actgttttag tcaggtgact tcctttagaa
    48301 gttgtgatgg caaattcttc ttcttgtttg tcaatctcaa gaaccgtttc attgagatga
    48361 ataggggtat caaatccatt tagctgttca atcaagcggt tagtcaactc ttctccagtc
    48421 aggtttggga agcctggtac gtctaggatt tccttttcag ggtagagaat agcaggttgt
    48481 ccacctagct ggggaagaga gtcgatgatt tgaaccttgg cttggcgtag gtgggcataa
    48541 aaggctgcaa aaagcccgac aggaccacca cccacaatgg taatatcata gagttgagac
    48601 atagtttctc ctttgttttt tctagtcagt ttattttatc atatttttgt tcaatgtaaa
    48661 atggactagg atagggaaaa aaatgccaga aaatggtata ataggacgaa agtgttttga
    48721 tagggaggat atcagggatg aattttcaac aattatccaa tctgcaatat tggaccagtt
    48781 tgtttgcaag tccatggacg atagctatca atctgattga tattttgatt gttgcttata
    48841 ttttatacca ttttacaaaa gctattgcag gaaccaagat tatgattttg gtacgtggag
    48901 ttttggtgtt tattttagct caaatccttg caaatatgat tggtttgact acgatttctt
    48961 ggttaatcaa tcaaattatt acttatgggg ttattgcggc ggttgttatc ttctctccag
    49021 agattcggac tggtttggaa cgtttgggaa gagcgacaga ttttttttcc aatgccccta
    49081 ttagtgctga ggaacagatg attcgtgcct ttgttaagtc tgttgaatac atgagtcctc
    49141 gtaaaatcgg ggccttggtt gctattcagc gtgtacgtac cttgcaggag tatatttcga
    49201 caggaattcc cttggatgct aagatttctg cagaacttct cattaacatt tttattccca
    49261 acactcccct acatgatggt gcggtgatta tcaaagaaga acgtatcgct gtgacgtctg
    49321 cctatctgcc cttgacaaaa aacacaggga tttccaagga atttgggacc agacaccggg
    49381 cggctatcgg tttatcagaa gtctcagatg ccttgacttt tgtcgtatca gaggaaacgg
    49441 gaggaatttc gataacctat aatggaaggt ttaagcacaa cctaacactt gatgaatttg
    49501 aaacagaatt acgtgaaatc ttacttccaa aagaggaagt gggtcttagt tttaaagaac
    49561 gattgctagg aggatggaaa catgaaaaaa aatagtttat atatcatatc ctcactcttt
    49621 tttgcttgtg tcttatttgt ctatgctacg gcgacgaatt ttcaaaacag taccagtgct
    49681 aggcaggtaa aaacggaaac ctatactaat acagtaacaa atgtccctat tgacatacgc
    49741 tataatagtg ataagtattt tattagcggt tttgcttcag aagtatcagt ggtcttgact
    49801 ggtgcaaatc gcctatcgct agctagtgaa atgcaagaaa gtacacgtaa attcaaggtt
    49861 actgctgacc taacagatgc cggtgttgga acgattgaag ttcctttgag cattgaagat
    49921 ttacccaatg ggctgaccgc tgtggcgact ccgcaaaaaa ttacagtcaa gattggtaag
    49981 aaggctcaga aggataaggt aaagattgta ccagagattg accctagtca aattgatagt
    50041 cgggtacaaa ttgaaaatgt catggtgtca gataaagaag tgtctattac gagtgaccaa
    50101 gagacattgg atagaattga taagattatc gctgtcttgc caactagcga acgtataaca
    50161 ggtaattaca gtggttcagt acctttgcag gcaatcgacc gcaatggtgt tgtcttaccg
    50221 gcagttatca ctccgtttga tacaataatg aaggtgacta caaaaccagt agcaccaagt
    50281 tcaagcacat caaattcaag tacaagcagt tcatcggaga catcttcgtc aacgaaagca
    50341 actagttcaa aaacgaatta aaaatagaaa aggattttat aacaatgggt aaatattttg
    50401 ggactgatgg agtccgtgga gaagctaacc tagaactaac accagaatta gcctttaaac
    50461 taggacgttt tggaggctat gttcttagtc aacatgaaac ggaagcgccg aaagtctttg
    50521 taggacgtga cacacgtatt tcaggggaaa tgctggaatc ggccttggtg gcaggtctcc
    50581 tttcagtagg gattcacgta tacaaacttg gtgtccttgc aacaccagca gtagcttact
    50641 tggttgaaac tgaaggagca agtgccggtg tcatgatttc tgctagccac aacccagccc
    50701 ttgataacgg aatcaagttc tttggcggtg atggcttcaa actagatgat gaaaaagaag
    50761 cagaaattga agccttgcta gatgctgagg aagacactct tcctcgtcca agtgcagaag
    50821 gcttaggaat cttggtagat tatccagaag gcttgcgtaa gtatgaagga tatcttgttt
    50881 caactggaac tcctcttgat ggaatgaagg ttgccttgga tacagctaat ggagcagctt
    50941 ctaccagtgc ccgtcaaatc tttgcagacc ttggtgccca attgacggtt atcggggaaa
    51001 caccagacgg tcttaacatc aaccttaatg ttggttcaac acatccagaa gcccttcaag
    51061 aagtggtcaa agaaagtggg tcagctattg gtttggcctt tgatggagac agtgaccgct
    51121 tgattgctgt tgatgagaat ggtgacatcg tcgatggtga caagattatg tacatcatcg
    51181 gaaaatacct ttctgaaaaa ggacaattgg ctcaaaatac aattgtgaca actgttatgt
    51241 ctaaccttgg tttccacaag gccttgaatc gcgaaggtat taacaaggca gttactgcag
    51301 ttggtgaccg ctacgttgtt gaagaaatga gaaaatcagg ctacaacctt ggtggtgaac
    51361 agtctggtca cgttatcttg atggattaca ataccacagg tgatggtcaa ttatcagcag
    51421 ttcaattgac taaaatcatg aaggaaactg gtaagagctt atcagagttg gcggcagaag
    51481 taacgattta tccacaaaaa ttagttaata tccgagtgga aaacgtcatg aaggaaaagg
    51541 ccatggaagt gccagctatc aaggccatca tcgagaagat ggaagaagaa atggcgggga
    51601 acggccgtat ccttgttcgt ccaagtggaa cagagcccct cttgcgtgtt atggcagaag
    51661 cgcctacaac agaagaagta gactactatg ttgataccat cacagatgta gttcgtgctg
    51721 aaattgggat tgactaaatc ctagaaaact agatgaaaat aaaaaattat gatacaatag
    51781 cttataatat tgtagccgat ggagaaagac atgaatctta aacgtgaaca agaatttgtt
    51841 agtcagtatc attttgatgc gcgtaatttt gaatgggaaa atgaaaatgg agctcctgaa
    51901 accaaggtgg atgtgaattt ccaattgctc caacatgacc aagaaaatca agtgacttcc
    51961 ttgattgtca tcttgagctt tatgattgta tttgataagt ttgtcattag tggaacaatc
    52021 tcacaagtaa accatatcga tggccgtatt gtcaatgaac caagtgaatt gaaccaagaa
    52081 gaggtggaaa ccttggctcg tccatgtttg aacatgctca atcgtttgac ttacgaagtg
    52141 actgaaattg cattagactt accaggaatt aatttggagt tctaatatga aattagctgt
    52201 tttcacagat tcctctgctt atctcagtgc agagaccttg caaagagaag acttgtttgt
    52261 cttggatatt cctgtcaata ttgatggtga ggaatatgtc gaaggcatca atctgtctgc
    52321 tgaggaattt taccaaaaaa tggctcaggc ttctgaattt cctaagacca gtcaaccaag
    52381 tattgccaag ttagatgaaa tcttaacttc gctcaaagaa caaggctata cacatgcctt
    52441 ggggcttttc ctatcttctg gaatttcagg tttttaccaa aatatccagt atatggtcga
    52501 tgactatgag ggcttaacca ttgctttccc agacactttg attacaagtg ctcccctagg
    52561 catcatggtt gaaagcgtct ttaattggcg tgatcagggc gatgattttg ccagcattca
    52621 ggataagcta gccattcaaa tcagccgtac gtcagccttt atcatggtag atgacttgga
    52681 tcatttggta aaaggtggac gcctttcaaa tggggctgcc attttgggca atttgcttag
    52741 cattaagcca atcctttatt ttaacgatca aggtgtgatt gaagtttacg aaaaagttcg
    52801 tactgaaaag aaggccacca agcgcttaat tgaaattatc aaggaaacaa cggcttcagg
    52861 tcaataccgg gtcattgtca ttcatgggaa tgctcctgaa aaggctgaag aattgcgtca
    52921 gcacttgctt gattttggct tgggttcgga tgtttcactt gctacatttg gtagtgtcat
    52981 tggaacgcac ctaggagcag gaagtattgc tctgggttat attccagtga tttagttggc
    53041 gcttctaggc tagttaagat gccttgtatc ttagaaattg aacacggact acctgcctct
    53101 tgaaaaaaga tgcctgtctt gcctttcgtg gaaagtcagt gccattccct atttttcaga
    53161 ggcagctaag gtcctttgta tcttgataat tgaacacgcc tggaaccctg tgtgaaaaag
    53221 atagttcttc caagaagtag acacttcttg attggaattc ctattttcac tttgtgttct
    53281 tacggacttt gtatcttaga caggagtaga gatgagtatt cgagtaatta ttgccggttt
    53341 taagggaaag atgggccagg ctgcttgtca gatggtattg actgatccag acttggactt
    53401 ggtggcagtt ttggatcctt ttgagtctga gtcagaatgg cagggtattc ctgttttcaa
    53461 ggataaggct gatttagctg gttttgaagc ggatgtctgg gtagatttta ctactccagc
    53521 tgttgcctac gaaaatacac gttttgctct tgaaaatggc tttgctccag tagttggaac
    53581 gactggtttc acgagtgaag aaattgcaga gctaaaagaa ttttctcgtg cccaagactt
    53641 gggtggcctg attgccccta actttgcctt gggtgctgtc ttactcatgc aatttgcgac
    53701 gcaggctgcc aaatatttcc caaatgtgga gattattgag ctccatcatg acaagaaaaa
    53761 ggatgctccg agtggaacag ccattaaaac agctgagttg atggcagagg ttcgagagtc
    53821 cattcagcaa ggtgcagcag atgaggaaga gctgattgct ggtgctcgtg gtgctgactt
    53881 tgatggtatg cgcatccact cagttcgttt gccaggcttg gtagctcatc aggaagtcat
    53941 ctttggcaat cagggagaag ggttgaccct ccgtcatgac tcctatgatc gcatctcctt
    54001 catgacagga gtcaatttgg gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg
    54061 attagaacac ttattatgag attaatgcaa atgccttctg aatttcagaa ggctttacca
    54121 gtattagaaa aaattaaaga agcaggcttt gaggcttatt ttgttggggg ctctgttcga
    54181 gatgcccttc tccatagccc tatccacgat gtggatattg cgacgtcttc ttatccagaa
    54241 gagaccaagc agatttttcc gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg
    54301 gtcttagatg gggatgagga gtatgaggta acaacctttc ggacagagga tgtctatgtg
    54361 gactatcgca gacccagtgc ggtttccttt gtgcgctcgc tagaagaaga cctcaaacgc
    54421 cgtgatttca cagtcaacgc ctttgccttg gatgagacag gagaaatcgt tgacttgttc
    54481 catggtttag aagatttgga aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt
    54541 ttcaacgaag atgctttacg gattatgcgt ggtttccgtt ttcaggctag tcttggtttt
    54601 gcacttgagc cagaaacatt taaagctatg aagaccttga cgccgctttt ggagaaaatt
    54661 tctgtagagc gtaccttcgt cgagtttgat aaactcttgc tggctccatt ttggagaagg
    54721 ggcttggctt ccatgattga gagtcaagct tatgactatc tccctgatat ggcatctagc
    54781 caggacaagc tcaacagact gtttgatttg gagactgatt ttacttttga atcctctgaa
    54841 caagcctggg cggctttact atgggctttg gagattgaaa atgcgcagtc atttttgaaa
    54901 tcttggaaga cctcacgcca gtttgccaag caagttcagg atttgctgat tattttggct
    54961 ctgcgtgaaa atggagaatt gagtaagcgt gattgttatc gctttgactt ggatttactt
    55021 ttacaggctg aaaatcttcg tcaagctcaa ggaaaagaag tcaacccaca agtcattaaa
    55081 gaaacctacc agagcttgac tattcatgat aagaaagaaa tccaaatcaa cggcggtatt
    55141 ttgatcaagg aatatggcta tcagccaggc ccagacttgg gagagatttt aacagagatt
    55201 gagtttgcca ttgtcgatgg agaattggag aataatcgtg aagccatcca tgcttacctg
    55261 agggagaaaa aatgagtgat tttatcgttg aaaaactaag taaatccgtt ggtgacaaga
    55321 ccgtttttag ggatatttcc tttattatcc atgacttaga cagaattggt ttaatcggtg
    55381 tcaatgggac tggcaagacc acccttttgg acgtcctttc tggtgtttct ggatttgatg
    55441 gggatgtcag tcctttttca gctaaaaatg attaccagat tggttacttg actcaggatc
    55501 ctgattttga tgatagaaag acagttttgg atacggttct atctagtgaa ctcaaggaaa
    55561 tccagctcat tcgtgagtat gaattgatta tgctcgacta tagtgaggac aagcaggcgc
    55621 gtttggaacg tgtcatggca gagatggact ctctccaagc ttgggaaatc gagagtcagg
    55681 tcaagaccgt tcttagcaaa ttgggcattc aagacttatc tactcctgtt ggggaattgt
    55741 caggtggtct gagaagacgg gtacagttgg cacaagtctt acttggcaac cacgaccttt
    55801 tgcttttgga tgagccgacc aaccatctgg atattgcgat tattgagtgg ctgaccctct
    55861 ttttgaaaaa ttctaagaag accgtccttt ttatcactca cgatcgttat ttcttagacg
    55921 ctttgtcaac acggattttc gagttggagc gagcaggctt gaccgagtac cagggaaatt
    55981 accaggacta tgttcgccta aaggcggaac aggatgagcg cgacgcggct cttcttcaca
    56041 aaaaagaaca actctacaaa caagaattgg cctggatgcg cagacaaccg caggcgcgtg
    56101 cgaccaagca gcaggcccgt atcaatcgat tccatgatct gaaaaaggaa gtttcaggca
    56161 gtagtgctga gacagacttg accatgaact ttgaaaccag tcggattggg aagaaagtca
    56221 tcgagtttca ggctgtttcc tttgcctatg aaaacaagcc tattttgcaa gattttaatc
    56281 tcttggtgca ggccaaagac cgtatcggaa tcgttgggga caatggtgtt ggaaaatcaa
    56341 ccctgctcaa cttgattgca ggaagtcttg agccaactaa aggacaagtt gtgattgggg
    56401 aaactgttcg catcgcctat ttctctcagc aaattgaggg tttggatgaa agcaagagag
    56461 ttatcaatta cctgcaggaa gtggcagaag aggtcaagac cagtggcggt tctacgactt
    56521 cgattgcaga gttgctggag cagttccttt tcccacgttc gacgcatgga accttgattg
    56581 agaaattgtc agggggtgag aaaaaacgtc tttatctcct caaactgctt ttggaaaaac
    56641 caaatgttct tcttttagac gagccaacca atgacctaga tattgcaact ttgacagtct
    56701 tagagaattt cttgcaaggt tttgcaggtc ccgttttaac agtcagtcac gaccgctatt
    56761 tcttggataa ggtagcgacc aagattctcg cttttgagga tggcaagatt cgtcctttct
    56821 ttggtcatta caccgactat cttgatgaaa aagcttttga aacagatatg gccaatcaag
    56881 tgcaaaaggt cgaaaaggaa aaagtggtca aggttcgaga agacaagaaa cgcatgacct
    56941 accaagaaaa gcaggagtgg gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta
    57001 tcgctgctat tgaagaggaa atgcaggcta acggctctga ctttggtaag ctgactactc
    57061 tccaaaaaga attggatgag aaaaatgaag cactccttga aaaatacgaa cgctatgagt
    57121 atctcagtga atttgatagt taagactatt cgaaaatcaa agtgcaaact atgtcggctt
    57181 cacattgccg actcaagtac agcctgtgac cggcttccta atttgcactt tgatttttat
    57241 tgagtataaa agaatagaaa aatcccgtct catgaaagga tttctctatt cttttttggt
    57301 ttcttgatga aagatatttt gccaggtttc gtggcgacgc cagatactgg tatggatgat
    57361 accatctaac tcatagcaga tgagtttggt tttttgactg atggaagtaa tttgaatgtc
    57421 ctttatagca gaatttaact cttttttggt cttataagcc tctttatcca tctgctctcc
    57481 atcttggcga atatagacaa aatcatcagt caagagttct tctagttggt ttccttggtc
    57541 aatcaattgt tcacgcataa gcaatttttt atagacattg tctaaaattt catcctcagg
    57601 gataggtgct ggttcgatat ggacatcggt atcaaagacg ccaaaacgct cctccagcat
    57661 agactcgacc tgatccgcga tttcatggct ttcaaaaaca gacaagtcag gattcatctc
    57721 tagtgtaata tccaggtaga tgttgctacc gtaggtgcga cctctttgcg atttgacctt
    57781 gctgattttg ggaatttcca tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa
    57841 gccatctgaa agactaaagg aagactcgat gaagatatca taggcagtct tcaagataaa
    57901 gaaagtgatg atgatagcaa ccagtttatc cacaatcgga taattgaaac tactagctag
    57961 gatggcaatg gcggttccaa gtgaggtaac agcgtcagaa agattgtcct tagcagctgc
    58021 cttcagcgcc ttggagttgg atttcttact gaggcgagta ttgtagagat agaccacaaa
    58081 cataatcgct gcagaaatga ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc
    58141 ccgactgaga atcttttgaa tggtatctct tagaacatcg aaaccgacat agaacatgat
    58201 gatagaagtg atcaagcttg ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg
    58261 gtctgcaggc tggcgcgcca tccgaatccc gattaagagg gccacatttc caatgatgtc
    58321 cgatacgtta ttaaaaccat cggccaccaa actggatgaa tgaaggagat gaccagctgc
    58381 taatttagct gcagacaaga tcaaataggt cgaaatactg ataatggctc cacgctcagc
    58441 taacttgaga tttgagatag attgcttcat tcaacttcct ttctagtcac atagcattct
    58501 accattatac tggttttcaa ggaaaaattc aaataaggca gtttttactc tttgaaaact
    58561 ccccaaaatt tggtataatg gtactactca agggagtagc tggcagaaac ctgtgatagt
    58621 gtcgtcattc cgaattttat gctgaaaagt atgctttccg gccctatctt aaacagcgag
    58681 acttgttatg attaacaggt ctctttttgt ttgtcgtgaa aagatatgac agaaagagag
    58741 tctgttttgc acacaatgtc aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg
    58801 ttttatactc agagccctga agaggtcttg caggctgtgg atgcgaccga gcaaggtttg
    58861 tcatcaagtg aggcggaaaa gcgccttgcc gaatttgggc acaatgaact cgaagaaggc
    58921 gagaaacgat caatcttggt caaattcatc gagcaattta aggatttgat gattatcatc
    58981 ctagttgcgg cagcaatctt gtcagtcgtg acttctggtg gggaagatat cgcagatgcc
    59041 attatcatcc tagctgtggt tatcatcaac gctgcctttg gtgtttacca agaaggaaaa
    59101 gctgaagaag ctattgaagc cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt
    59161 gatggacaca tggcagagat tgactctaaa gaattggtac caggcgatat cgttgccctt
    59221 gaagcaggtg acgtggtacc agcggaccta cgtttgatag aagccaactc tcttaaaatt
    59281 gaagaagcag ccttgacagg tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt
    59341 gcgacagatg ctggtattgg tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc
    59401 tatggtcgtg ggatgggtgt tgttgtcaat acaggtatgt acactgaagt tggtcatatt
    59461 gctggtatgc ttcaagatgc ggatgagact gatacaccac tcaaacaaaa cttgaacaac
    59521 ctttctaagg tcttgaccta tgctatcttg gtcattgccc ttgttacttt tgtagtgggt
    59581 gtcttcattc aagggaaaaa tccacttggt gagttgttga cttctgttgc ccttgccgtt
    59641 gcagccattc cagaaggact tcctgctatc gttaccatcg ttctttctct tggtactcaa
    59701 gttttggcca aacgacattc catcgttcgt aagttgccag cagttgaaac acttggttca
    59761 actgaaatca tcgcttctga taagactggt acgctgacta tgaacaagat gacagtcgaa
    59821 aaagtcttct acgatgcggt tctacatgac tcagctgatg atattgaact aggtcttgaa
    59881 atgccactac ttcgttcagt tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac
    59941 ttgattggtg acccaaccga aacagccttt atccaatatg ccttggacaa gggctatgat
    60001 gtcaaaggtt tcttagagaa atatcctcgt gtagctgaat tgccatttga ctctgaccgt
    60061 aagctcatgt caacagttca cccattgcca gatggtcgtt tccttgtagc agtcaagggt
    60121 gcgccagacc aactcttaaa acgttgtctt cttcgtgata aggctgggga tattgctccg
    60181 attgatgaga aggttacaaa tctcattcat acaaacaatt ctgaaatggc tcatcaagcc
    60241 ttgcgtgtcc ttgcaggtgc ttataagatt atcgatagta ttccagaaaa tctcacttct
    60301 gaagagcttg aaaatgattt aatttttact ggtttgattg ggatgattga ccctgaacgt
    60361 cctgaagccg ctgaggctgt tcgtgtggct aaggaagcgg gaatccgtcc aattatgatt
    60421 acaggtgacc accaagacac agcggaagcc attgccaaac gtttgggaat cattgacgca
    60481 aacgatacag aaggtcacgt tttaactggt gctgaactca atgaactgtc agatgaagaa
    60541 tttgaaaaag tcgttggtca atactctgtt tatgcccgtg tgtctccaga acacaaggtt
    60601 cgtatcgtca aggcttggca aaaacaaggt aaagtcgttg ccatgacagg tgacggtgtc
    60661 aatgacgcgc cagctctgaa aacagccgat atcggtatcg gtatgggaat cactggtaca
    60721 gaggtttcta agggggcttc tgatatgatt cttgcagatg ataactttgc gactattatc
    60781 gtcgcagtgg aagaaggacg taaggtcttc tcaaacattc aaaagactat tcagtaccta
    60841 ctttctgcta atactgctga agtattaacc atcttcctat caaccttgtt tggttgggat
    60901 gtcttacagc cggttcatct tttgtggatc aacttggtaa cggatacctt cccagctatc
    60961 gctcttggtg ttgaacctgc agaacctggc gtcatgaatc ataaaccacg tggacgcaag
    61021 gcaagcttct tctcaggtgg tgttttgagt tctatcattt atcaaggtgt actccaagca
    61081 gctcttgtta tgagtgttta tggccttgcg attgcttacc cagttcatgt gggtgacaat
    61141 catgctattc atgcagatgc cctaacgatg gcctttgcaa cccttggttt gattcagctc
    61201 ttccatgcct acaatgtcaa gtctgtctac caatccatct tgacagttgg cccattcaag
    61261 tctaagacct ttaactggtc catcttggta tcctttatcc ttctcatggc aacaatcgtt
    61321 gtagaaccgc ttgaaggaat cttccacgta accaaactag acttgtcaca atggggaatt
    61381 gttatggctg gaagcttctc aatgattatc atcgtcgaaa tcgttaagtt tattcaacgc
    61441 aaactcggtt ttgacaagaa tgcgatttaa gggaggtttc ggatgtcagc atatcaatta
    61501 ccgaccgtat ggcaggatga agctagtaat caaggagctt ttacggggct aaacagacca
    61561 acagcaggtg cccgtttcga acaaaacttg ccaaaaggag aacaagcttt tcagctttat
    61621 tcactgggaa caccaaatgg tgtgaaggtt actatcttat tggaagaatt actagaagct
    61681 ggttttaagg aagcggctta cgacttgtat aagattgcta tcatggatgg ggatcaattc
    61741 ggctcagact ttgtgaagct caatccaaat tccaagattc cagccttatt ggaccagtca
    61801 ggtactgaaa gcgtaagagt ctttgagtct gctcatattc ttctttacct tgctgagaaa
    61861 tttggagcct ttttaccaag taatcctgtg gaaaaggtag aagttttgaa ttggctattc
    61921 tggcaagcag gtgcagcacc ttttctaggt gggggatttg gacatttctt caattatgct
    61981 cctgaaaaat tggaatatcc tattaaccgt tttacgatgg aagtgaaacg ccagttggat
    62041 ttattggata aggaattggc tcagaaacct tatattgcag gcaatgacta tacgattgca
    62101 gatattgcta tctggtcttg gtatggacag ttagttcaag gaaatcttta ccaaggttct
    62161 gcaaaattct tggatgcctc aagttatcaa aatctagtaa aatgggcaga aaaaattgcc
    62221 aatcgtccag ctgttaagcg tggattggaa gtaacttata cagaaattaa atagcaaaaa
    62281 agtcatcttc ggatggcttt ttgctacagt tgagggaaag ggtttgcagt tatcggcttt
    62341 tgtgctataa ttgctataat atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa
    62401 aattgtgaag gatatcttat ttttatctca agtgtctcag ccggcaagtc aggaggacct
    62461 ttatcttgcc agagatttgc aggatacact cttagcaaat cgtgatacct gtgttggtct
    62521 agctgccaat atgattgggg tgcagaagcg cgtgattatc tttaatcttg gcttggttcc
    62581 cgtggtcatg tttaacccag tgcttctgtc ctttgaagga tcttatgagg cagaagaagg
    62641 ctgtttgtcc ttggtaggtg tgagatcaac taagcgttat gaaaccataa ggcttgccta
    62701 tcgtgacagc aagtggcagg aacagaccat taccttgaca ggcttcccag ctcagatttg
    62761 ccagcatgag ctggatcact tggaaggacg aatcatttag gaggaaagca aatgaaacga
    62821 atagtctttg aacttatttt tatcgcaacg acctggtata tctttttacc gccccttaac
    62881 ctgaccagct gggaatttct cttcttcctc tgtgggcatt tgttagttgt ggcaatctta
    62941 tttggctttg gcaaggggat aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg
    63001 gaagctgcct taaatcttga gggtttcaaa atcaatcggt tagggaaaat tctgttagct
    63061 tcgattggag gaattcttct cttggcagct ttggtttcct tggtaacttc cagcatgttt
    63121 caggctaaaa attatgccaa tgtagtcacg gttacggaaa aagactttac tgaatttcct
    63181 aggagtgaca ccagtaaggt tcctatccta gatagaagta ctgctgaaaa aattggagac
    63241 cgctacttgg gttccctaac cgataaggtg tcgcaatacg tagcggcaga tacctatacc
    63301 caattgacaa ttgatgggaa accttatcgg gtcacaccac tagaatatgc agaccctatc
    63361 aaatggttta acaatcaagc caagggaatc ggtgagtata tcaaggtgga catggtaact
    63421 ggaaatgcgg atttggtgga cttgaagaca ccaatcaagt attcagactc ggagtatttt
    63481 aaccgtgatg tcaaacgtca cctgcgcttg aagtacccga ccaaaatctt taaaactcca
    63541 tcttttgagg tggacgatga gggcaatcct ttctatgtag caacggttta ccaaaagcaa
    63601 tttggacttg ctgttcctcg tcctgcttca gtcattatct tggatgctac aaatggagaa
    63661 accaaggaat acagcttatc agatgttcca gaatgggtgg acaggatcta tccagcagag
    63721 gaaaccattg agcaaatcaa ctacaacggc aagtacaagg acggtttctt gaatgccatg
    63781 atttccaaga aaaacgtgac ccagactacc aagggctata attacttgtc tatcggtaat
    63841 gacatctatc tctacacagg tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc
    63901 atccttgaaa atatgcgaac aggagaaatc actaagtata gcttggcttc tgcgacagaa
    63961 gaatcagccc gtgaatcagc agaaggtgct gttcaggaga aatcctacaa agcaaccttc
    64021 ccaatcctca tcaacctcaa tgacaagcct ctctacatca tgggcttgaa ggacaatgct
    64081 ggcttggtca aagagtacgc cctggtagac gcagtcgagt accaaaatgt tatcgttgct
    64141 actacagtgg aagagatgct cagcaagtat gccaataaaa acgaccttga aattgacaat
    64201 gcaacgacag aaagcatcaa tggagtagta gcagacctca aatcagctgt tatcaaggga
    64261 gacactgtct acttctttaa agttgatggc aagatataca aggtcaaggc ttcagtatcc
    64321 gatgaccttc cttaccttga aaatggtaaa accttcgaag gtcaagtagg aaaagacaat
    64381 tatctcaaga cctttaagct acggtaaaaa taggtttttt tcagaaagta tatgttataa
    64441 taaggtaaat taagcctaat ggaggacaaa gaaatgggtt tttatttgat ggttgcttca
    64501 atgctactcg gactgctcgc tttgaagata ggtttttctc agttcaagga gaaaaaagat
    64561 aaattcttat ctatcttaac aagtttagct ggcacagccc ttgttctcgt ggctgtctgg
    64621 ttaggatggc ccaaataaat agaaaaacct cggtcaaacc gaggtttttc aaatgaattt
    64681 cttggttgtg gctaaaaaat atgctacact atcaatatga aaattttaat cccaacagca
    64741 aaagaaatga acacagactt gccaagtatc gaggcaattt ctttaaaacc agaaagtcag
    64801 gccgtgcttg atgccttggc tctctattct gccagtcaat tggagagttt ctacaaggta
    64861 tcagctgaga aagcggcgga agaatttcaa aatatccaag ctttgaaaag gcaaactact
    64921 caacactatc cagccttgaa actttttgat gggcttatgt accgcaacat taagagagat
    64981 aagctgaccg aggcggaaca agattatctt gaaaatcatg tcttcattac ctcggctttg
    65041 tacggtgttg ttccagcctt gtcacccatg gctcctcacc gtttggattt tttgatgaaa
    65101 ttaaaagttg ctggtaagac tttgaagagc cattggaagg cagtctatga tgaagctctg
    65161 aagaaggaag aagtgatttt ctctctcttg tcatcagagt ttgagactgt attttctaag
    65221 gaaatcagag caaagatggt gaccttcaaa ttcatggagg atagaggcgg tcagctgaag
    65281 attcactcaa ctatctccaa gaaagcgcgc ggggcctttc taacagcttt aatagaaaat
    65341 caagtacaaa ctgtggggga agcacgtcgc ttgaactttg ctggatttgt ttaccgagaa
    65401 gatttgtcac aaccacaggg attggttttt gtaaaggaag tatagaaatc agatattttg
    65461 tatttggcaa tatgtatcat cagctatttt agtttataaa tgagaaaaaa gcgaacaagc
    65521 tagtcttctg agcgtcagaa aagtagtctt gttcgctttt attatgttat actcttcgaa
    65581 aatctcttca agccatgtca gtgtcgcctt accgtatata tgttactgac ttcgtcagtt
    65641 ctatctacaa cctcaaagca gtgctttgag tagcttgcgg ctagcttcct agtttgcttt
    65701 ttgattttta ttgagtgtta gttacttgat agcttcgacc aagtcttgag cttgtttttc
    65761 aagtgagttt aggactgttt cttcaagaac caattttccg tctgcccagg cagagtcatt
    65821 aacacgtgca gcagtgaaat caccaacgcc ttgtgtacgg ataaatggca agaggtcttt
    65881 gtagatagcg aaaagttgat cgtgccctgc attggctaca gatgatactg tgacaaactt
    65941 gtcttgaagg gcagaaacgc cacgtgtatc agacaagtca agggcacgag atagccagtc
    66001 aagcaagttt ttcactgtac cagggataga gaagttgtag actggagaga aaatccagat
    66061 agcatccgca acgagaactg cttcacgagc agcagctaca gctggatgtg ttggaacttc
    66121 caaatcttgg ctgaagagag gaagggctga ataatcaagg tagctaactt ccgctttacc
    66181 agcaagtgct ttctcagctt cgagcgccat ttggtggttg aaagaacctt gacgtagtga
    66241 tccgacgata aataatactt ttttagacat gatgtgtctc ctttttctta aaatttcgag
    66301 aactctctcg ttgttataaa atatattaca acaaaacaaa agaacttgca agaaatttgc
    66361 tcagagttta tttgaaaatt gtaaaatttc ggaaactcta gtcatttgtg actgaaaaag
    66421 taagaactgt ttcactttca aaatcggttt tgtttgaagg gagaaataga attggttgct
    66481 caaagcacag ctttgaggtt gcagataaag ctgacatggt ttgaagagat tttcgaagag
    66541 tattcttata ttcacttgta ataaagctta atagatggta aaatagacga gtgaaaaaaa
    66601 gacaaaacaa agcaaaaaat aatctactgt ggcagtatgg tctagggatg acgattttgt
    66661 ttgtggttat cagtgcttcc tttctgtata tggtttctct tagcatgaaa ccctatcaaa
    66721 cagctaaaag tgaaggagaa aaattagctc agcagtatgc aggattagag caggctgatc
    66781 aggttgattt atacaatggc ttggaatctt attacagcgt tcttggtcgt aataaacagc
    66841 aagaagcgct tgctgtcctg attggtaaag atgaccataa gatttacgtt tatcagctaa
    66901 atcagggtat ttcacaagaa aaagcagaaa cggtttctaa ggaaaaggga gctggcgaga
    66961 ttgacaagat aacctttggt cgttatcaag acaagccaat ctgggaagtt aagtcaggat
    67021 ctgattttta tctagtagat tttgaaacag gagcattggt caataaggag ggcctatgaa
    67081 actatccaac cgtgttttag aaatggaaga aagtgtgact ttggctgctg gagcccgtgc
    67141 caaagcactg aaggctgagg gtagagatat tttgtctcta accttgggtg agccagattt
    67201 cactactccc aaaaatatcc aagatgccgc cattgcatcg attcgagatg ggcgtgcttc
    67261 tttttataca gtaacctcag gtctgccaga gcttaaggcg gtggtcaata gctactttga
    67321 gcgcttttac ggctattctg tagcgtcaaa tcaagtgaca gtcgctgcgg gagccaaata
    67381 ttctctctat accttcttta tggctgtggt caatccaggt gatgaagtca tcatcccaac
    67441 cccatactgg gttagctatg gagatcaggt caagatggca gaaggcgttc ccgtctttgt
    67501 ttctgctaag gaagacaatc actttaaggt gaccgtagag cagttagaag cagctcgcac
    67561 tgacaagacc aaggttttgg tgctgaattc gccatctaat cccacaggta tgatttacac
    67621 ccgtgaggaa ctcttggcaa ttggaaactg ggctgtagaa aatgatattc tcatcctagc
    67681 agatgatatc tatggccgct tggtttataa tggtcatgag ttcacaccga tttctagcct
    67741 atcggaagcg attcgcaagc aaacagtggt catcaatggt gtgtctaaaa cctatgccat
    67801 gactggttgg cggattggtt atgccgttgg agaagcagac attatcgctg ccatgtccaa
    67861 gattgcaggt caaacaactt cgaatccgtc agcagtagcc caatatgcag cagttgaggc
    67921 tctatcaggt gagcaagata ctgtagaaag catgcgtcag gcctttgagg aacgtcttaa
    67981 taccatctat cccctccttg cagaggtgcc aggatttgaa gtggtcaaac cacaaggggc
    68041 cttctatctc ttcccaaatg tcaaaaaggc catggagatg aaaggctaca cggatgtgac
    68101 agactttaca actgctatct tagaagaagc cgaagtggcc ttggtaacag gagctggatt
    68161 tggagcacca gaaaatgtcc gcctcagcta tgcgacagac ctagacacgc ttaaagaagc
    68221 agtcgaacgc ttgaaagcat ttatgggtag tgagaatgat tgatcatttt gagattaagg
    68281 taaaggattt acaaatttca gaaggatttt ataggagttt tctcgctcct ttggactata
    68341 aattggcttt taagactagt tctctaatta gttttctatc cccgaacagc cctcatcctg
    68401 gtggtgattt ttggctgact cagggaacac aagatcctgt tcattttgct tttttagcag
    68461 aaaataagga agaagttcag gcttgttatg aggctggctt agaggcaggt gggcgagaca
    68521 atggggttcc tggttatcga agtgagcatc cgatttatta tgctgctttt atgattgacc
    68581 tggatgggaa caatatagag gtggtttgcc ataaagaata aaaaagaaaa ggaaaaataa
    68641 tgacaaaacg tgtaacgatt attgatgtaa aagactatgt tggtcaggaa gtgacgattg
    68701 gcgcttgggt tgccaacaaa tcaggaaaag ggaaaatcgc tttcttacaa ttgcgtgatg
    68761 gaacagcctt ctttcaaggt gtggctttta aaccaaactt tgtcgaaaaa tttggtgaag
    68821 aagtgggact tgagaagttt gatgttatca aacgcttgag ccaagaaacg tctgtttatg
    68881 tgacaggtat tgtcaaagag gacgaacgtt ctaaatttgg ctatgagttg gacatcacag
    68941 acatcgaagt gatcggtgaa tctcaagact acccaatcac accaaaagaa cacggaacag
    69001 actttttgat ggataaccgt cacttgtggc tacgctctcg taagcaagta gctgtgttgc
    69061 aaatccgtaa cgctattatc tatgcaactt atgagttctt tgacaagaac ggttttatga
    69121 agtttgacag cccaattctt tcaggaaatg cggcagaaga ttctacagaa ctctttgaaa
    69181 ctgactactt cggaacgcca gcctacttga gccaatcagg tcagctttac ctagaagcag
    69241 gggctatggc tcttggtcgt gtctttgact ttggtccagt tttccgtgct gaaaaatcaa
    69301 aaacacgccg tcacttgact gagttctgga tgatggatgc tgagtactca tacttgacac
    69361 atgatgagtc gcttgacttg caagaagctt atgtgaaagc tcttctacaa ggtgttcttg
    69421 accgcgcgcc tcaagccttg gaaaccttgg aacgtgatac agaactcttg aaacgctaca
    69481 ttgcagagcc attcaaacgt atcacttacg atcaagccat tgacctcttg caagagcatg
    69541 aaaatgatga agatgctgac tacgagcatc ttgagcatgg tgatgacttt gggtcaccac
    69601 acgaaacttg gatttcaaac cactttggtg tgccaacatt tgtcaagaac tatccagcag
    69661 ccatcaaggc cttctacatg aaaccagttc ctggaaatcc agagcgcgtg ctttgtgcag
    69721 acttgcttgc tccagaaggc tatggagaaa ttatcggtgg gtctatgcgt gaggaagatt
    69781 acgatgccct tgtcgctaag atggatgaac ttggcatgga tcgtacagaa tatgaattct
    69841 accttgacct tcgtaaatac ggtacagttc cacacggagg atttggtatc ggtatcgaac
    69901 gtatggtaac cttcgcagca ggaacaaaac atatccgtga agctattcca ttcccacgta
    69961 tgttgcaccg tatcaaacca taagaacagg aaaacgccca tgtggcgttt tttcgaattc
    70021 tagtgttttt acttgcgtaa aaaaattttt tctagtataa tagtttattg tgagcgaacc
    70081 tcacttaccc cttgcaaagt cttggggtca ttagaccaaa aggaggaaca tatcaatggc
    70141 taaatacgaa attctttata tcattcgtcc aaacattgaa gaagaagcta aaaacgcttt
    70201 ggtagcacgt tttgactcta ttttgactga caacggtgca actgttgttg aatcaaaaac
    70261 ttgggaaaaa cgtcgtcttg catacgaaat ccaagatttc cgtgaaggac tttaccacat
    70321 cgttaacgtt gaagcaaatg acgatgcagc tcttaaagag tttgaccgtc tttcaaaaat
    70381 caacgctgac attcttcgtc acatgatcgt caaaattgac gcgtaagaag gtaaactatg
    70441 attaacaatg ttgtacttgt agggcgtatg acacgtgacg ctgagttgcg ttatacccca
    70501 tcaaatgtag cagttgcgac ttttactctt gcagtaaacc gtacatttaa gagtcaaaat
    70561 ggtgaacgtg aggctgattt tataaatgtc gttatgtggc gccaacaggc tgaaaatctt
    70621 gctaactggg ctaaaaaagg ctcacttatc ggggtgacag gtcgtatcca gactcgtagt
    70681 tacgataacc agcaaggaca acgtgtctac gtgacagagg tcgtggctga gaatttccaa
    70741 atgttggaaa gccgtagtgt gcgtgagggt cacacaggtg gagcttactc tgcaccaact
    70801 gcaaactatt cagcacctac aaattcagta ccagactttt cacgtaatga aaatccattt
    70861 ggagcaacaa acccattgga tatttcagat gatgatttac cattctaatg gacaactaaa
    70921 cttataaagg agaaaaaaca tggctcaaca acgtcgtggc ggattcaaac gccgtaaaaa
    70981 agttgattac atcgcagcaa acaaaattga atatgttgat tacaaagata ctgagcttct
    71041 tagccgtttc gtttcagaac gtgggaaaat ccttcctcgt cgtgtaacag gaacttcagc
    71101 taaaaaccaa cgtaaagtaa caacagctat caaacgcgct cgcgtaatgg ctttgatgcc
    71161 tttcgtaaac gaagattaaa gaaaagaccc ggttgggtct ctttttcatg agcttgaaaa
    71221 caagaaagcg aattaagacc ccaatgggtc ttttttcaca aactttgaaa tgagagagcg
    71281 agttaggctc agtggctccc tttttacgag tttgaaaaca agagaacaca ttaaaagcac
    71341 gatggagctt tttcataaat atgtcttttt tctcatccaa gaaattaaaa taaaaatgat
    71401 aaactttttg aaaatagggg atttgcctac tttatgatat aatggaaaga gttagattga
    71461 aagaggtagt gagatggacg cgaaattaag atacaaggca aagaagatca agattgtctt
    71521 ttttgatatt gatgatacat tgcggaattc aaagacaggg tttattccaa ctacaattcc
    71581 cactgttttt aaacagttgc gtgaaaaagg aattttaaca ggaatcgcct ctggacgtgg
    71641 catttttggt gttgttccag agattcgtga tctcaagcct gacttttttg taactttgaa
    71701 tggggcttat atcgaagata aaaaaggtca ggtcatttat cagcatcaga ttgaaaagtc
    71761 agatgttgag gagtatatct cttgggctaa gcaagaagga attgagtatg gcttggttgg
    71821 gagtcatgat gccaagttgt cgattcgcac cgatatgatg agtgaagcta tcaatccaat
    71881 ttatcccgac ttagatgtag atcccgattt ccatgaaaaa gaagatatct atcagatgtg
    71941 gacttttgaa gataagggag atgacttgca cttgcctgac agtctctcag acaaacttcg
    72001 catggttcgt tggcatcaac attcgtctga tattgtgccg atttcaggct ccaaagcgac
    72061 gggggtggaa aaggttgtgg aacaccttgg cttgaaacca gagaaggtca tggtttttgg
    72121 agatggtctc aacgacttgg aactctttga ttatgctgga atcagcgttg ccatgggaat
    72181 ttctcatgat aaaatcaaag aaaaagcaga ttatattaca aaaacattag aagaagatgg
    72241 catttttgat gccttagaag tatttggtat ggtagaaaaa gaattgcatt ttccacaagt
    72301 agacattgaa acagtagaag gtcctcttgc gactattaag accaatcacg gagacttacg
    72361 tatcaagctt ttccctgaac atgctcctaa aacagtggct aactttgtat ctctttcaaa
    72421 agatggctac tatgatggtg tcattttcca ccgtattatc aaggacttta tgatccaagg
    72481 tggagaccca actggaactg gtatgggtgg cgagtcaatc tacggcgaat cttttgagga
    72541 tgaattctca gaagagcttt acaatatccg tggtgctctt tccatggcaa atgctggtcc
    72601 aaataccaac ggcagccagt tctttatcgt gcaaaaccaa cacctacctt attctaagaa
    72661 agaaattact cgtggtggtt ggccagaacc gattgcagaa atctatgcca atcaaggtgg
    72721 gacacctcac ctagaccgcc gtcacacggt ttttggtcag ttagctgatg aagcatctta
    72781 cgctgtcttg gatgccattg ctgctgttga gacaggagct atggacaagc cagttgaaga
    72841 tgttgtaatt gaaactattg aaatcgagga ctaagatgaa aatcggtgat aagctaaagg
    72901 ggcgtattac agggattcag ccctacggtg cctttgttga gttagagacg ggtgatacgg
    72961 ggctgattca catttcagag attcggacag gatttattga aaatattcat gaaaccttga
    73021 aagtcgatga agaggttcaa gttcaggtag tggatttaga tgaatttacg gggaaagcca
    73081 gtctttctat ccgcactttg gaggaaaaaa agtaccagtt tcctagacgg agacgctttt
    73141 caagcgaccg ctttaactac ggttttgctc cctttcgacg aatgctacca atctggactg
    73201 gagaagccct gcaccattta aaaaagaaga agtagtttag agttttatat tttttgtaat
    73261 gttaatatga atttgctata ataggaccat ggaagaagaa caattattaa aatcaggaga
    73321 gcgcattaac cagctctttt cgacagatat caaaatcatt caaaatagag aggtttttag
    73381 ctattcggtg gatagtgttc tcttatcacg atttccacgt tttcctaaga aggggttgat
    73441 tgtggatttc tgtgctggga atggagcagt ggggcttttt gctagcactc gtactcaagc
    73501 acagatattg tctgttgaga ttcaggagcg tttggcggat atggctgaac gctctgtccg
    73561 tttgaatgga ttagaggagc aaatgcaggt catctgcgat gatttgaaaa atatgcctgc
    73621 tcacattcag gggagtaagg tggatatgat tttgtgtaat ccaccctatt tcaaggtgga
    73681 tccttattct aatctgaacg agagtgaaca ttatctcttg gctcgacacg aaatcacgac
    73741 taatttggaa gaaatctgtc gtagtgccca gagtattctc aagtctaatg ggcgtttggc
    73801 catggttcat cgtcctgatc gacttctgga tattttggat acgttaaaac gacataatct
    73861 agcccctaag cgcctgcagt ttgtttatcc aaaaagagaa aaggaagcca atatgctttt
    73921 gattgaggcg atcaaggatg gctcaacaag tggctttaag gtcttacctc ctttgattgt
    73981 ccacaatgat gatggctctt atacgcccga aatcgaagag atttattatg gatcataagg
    74041 cttatatgta cgttctggag tgtcgtgatg gatcctacta tataggctat acgactgata
    74101 tgagaagacg cctcgctatc cacaatagtg ggaagggagc caaatataca cgagcacgct
    74161 tgccagtcaa acttatctat gctcaaggtt ttgccagtaa ggaagaagcc atgtcggctg
    74221 aagctcttct caagcgtaag aagaggccac agaaggaaga atttttatct gaaaatcaag
    74281 atagaaattt actcagttat tttgaagaat cgtggggagt cctttgactc ctcttacctt
    74341 tgtcaaaaag cgaaaaaaat gctacaataa agaaaataaa caaaatgagg tattatcatg
    74401 tccaagattc tagtatttgg tcaccaaaat ccagactcag atgccatcgg gtcatctgta
    74461 gcttttgcct accttgcaaa agaagcttac ggtttggata cggaagctgt tgcccttgga
    74521 actccaaatg aagaaacagc ctttgtcttg aactattttg gtgtggaagc accacgtatt
    74581 atcacttctg ccaaagcaga gggggcagag caagttatct tgactgacca caatgaattc
    74641 caacaatctg tatcagatat cgctgaagta gaagtttatg gtgttgtaga ccaccaccgt
    74701 gtggctaact ttgaaactgc aagcccactt tacatgcgtt tggagccagt tggatcagcg
    74761 tcttcaatcg tttaccgtat gttcaaagaa catggtgtag ctgtgcctaa agagattgca
    74821 ggtttgatgc tttcaggttt gatttcagat acccttcttt tgaaatcacc aacaacacac
    74881 ccaacagata aaatcattgc tcctgaattg gctgaattgg ctggtgtgaa cttggaagaa
    74941 tatggtttag caatgttgaa agctggtacc aacttggcta gcaaatctgc tgaagaattg
    75001 attgacatcg atgctaagac ttttgaactc aacggaaata atgtccgtgt tgcccaagtg
    75061 aacacagttg acatcgctga agttttggaa cgccaagcag aaattgaagc tgcaatgcaa
    75121 gctgccaacg aatcaaacgg ctactctgac tttgtcttga tgattacaga tatcgtcaac
    75181 tcaaactcag aaatcttggc tcttggtgcc aatatggaca aggtcgaagc ggctttcaac
    75241 ttcaaacttg aaaacaatca tgccttcctt gctggtgccg tttcacgtaa gaaacaagtg
    75301 gtacctcaat tgactgaaag ctttaatgcg taagattttg ggtgtcagct caaaatcgga
    75361 aagtctagtt tgccttatat cgaaaggagt ttcggctcct tttttctagg agtgaagtat
    75421 gttagaaaat ggcgatttga tttttgtgag agatgggtca gacatgggac aggccatcca
    75481 gacttccaca ggtaactata gccatgttgc catttatttg gatgggatga tttatcatgc
    75541 tagtggacag gctggtgttg tctgtcaaga accggcagac ttctttgagt ccaatcattt
    75601 atacgacctc tatgtttacc cagaaatgga tatccagtcg gtgaaggaaa gagcttgcaa
    75661 acatcttgga gcaccctaca atgcttcttt ctatccagat gcagctggtt tctactgctc
    75721 ccagtatata gcagaaatcc tacctatttt tgaaactatt cctatgaaat ttggagatgg
    75781 ggagcaggag attagtgatt tttggaggga gtattacata gaactaggtc tgcctgttcc
    75841 tctgaaccaa gctggtacca atcctagtca gttggcagca tcgcctctgt tacaatgtaa
    75901 agaaagggat cttcatgatt cagattttta atccatctcg tttgacgaga cagccatttt
    75961 tggagaattg atccgctatc tggaccagta tgaggatgtg attctacggg aaattaaggc
    76021 tcaatttcca gatgttgcag ttgataaact catggaagag tatataaagg caggcttgat
    76081 tctacgtgaa aataagcgct attacctcaa ttttcctacg cttgaatcac ttgatagtct
    76141 tgaactggat caagagattt ttgtcagaga agctagtccg gtctatcaag ccttgttgga
    76201 gcagagtttt gagacggaat tgcgcaatca aatcaatgca gctattttag ttgaaaagac
    76261 ggactttgcg cgcattaaaa tgaccctgtc caattatttt tacaaggtca aacagcagta
    76321 tcctttgaca gaaaaacagc aggagctcta tgacatttta ggagatgtta atcctgagta
    76381 tgccctcaag tatatgacgg cttttttgtt gaaatttctc aaaaaagacc agcttatgca
    76441 gaaatgccgt gatatctttg tggacagttt ggttgtctta ggctatattg tgcaaaatga
    76501 agatagaaag tatgagttgg ctatcgattt tgataaggag agattaactt tctacttagc
    76561 gtgatttctt gtttctgagc acattgtttg actttcctta gtattcggta taaactatat
    76621 gtaaccggta acacatatcg gaataaacta aaggagacaa tcatatgtca cttgaaaaca
    76681 aattggaaca agcaacaggc gctgtcaaag aaggttttgg taaagttact ggagacagca
    76741 agacagaact tgaaggagct gttgaaaaaa cagttgctaa ggcaaaagac gttgtagaag
    76801 acgcaaaagg tgctgtagaa ggtgccgttg aaggtttgaa aaacgttttt actaaataat
    76861 aggaaaaaat caagggtttc attttccctt gattttttct attcttataa ataattttct
    76921 gcgacggctg tatctcctgg gtaggattct ttcttgccct ggatgatttg gtaacaatcg
    76981 actcccttac ccgcaataat aactgcatct aattcgtgat ttgtgatagc cattgccgcc
    77041 ttgatggctt cttggcgatc cgcaatcttt tcaacaggat gattgatgta gctactaatt
    77101 tcatctgcaa tggccattgg gtcttcatag ttagggtcat cagcagtcag aaagacttga
    77161 atctcagggt gttgattgag gaggaggcca aagtccttac gacgactttc tcccttgttt
    77221 cctgttgatc ccagaaccag agcaatcttt ccggtttgat gagtttcaac cacattgatg
    77281 agttttttca gactatcccc attgtgggca tagtcgatga agaccttggc tccatttttc
    77341 tgagtgagga cttccatacg accaggaacg cgggttgcag cgatgccttt tttgatgtcc
    77401 tcaagacttg ctccgagacg gagacaagca agtccagcag caactgcatt ttcttggttg
    77461 aagttgccaa tgagttgaat atcataatct ccagcgagtt tacccgtagc tgaaaagcta
    77521 aaggctttgg aattctcgat ttggttatca aattggctac catagaaatc atggtcttga
    77581 tcttcaacct gttctttcaa gactgagaag tggtccatgt cactgttaat gatgactgct
    77641 cggctctttt ccatcaagag acgcttgtgg tagaaatagt cttcaaagct agggtgttca
    77701 atcgggccga tatggtctgg gctgatattt aggaaaactc ccacatcaaa ggttagacca
    77761 tagacacgtt tgaccagata ggcttgactg gagacttcca tgatgaggtg ggtacggtca
    77821 ttttgcacag cctgattcat catgtcaaag aggtcaatac tctcaggggt tgtcaacgct
    77881 gacttaaaga aagtctcgcc atcaagagtt gtgttcatgg tcgacaacat agcaggtcta
    77941 tgcccttgag ataagatgtt ataggcgaaa taggctgctg ttgtcttacc cttagtacca
    78001 gtaaaggcaa ggagtttgag tttttcctgt ggattaccat agaactccat ggcaatcaaa
    78061 ctcatggctt tctttatatc gttcacaatg atgacaggga taccgacttc gtagtccttt
    78121 tcagctacat accaagctaa tccttgtgtt atagcagaaa gaaggtattc ttttttaaag
    78181 gcagcgcctt ttgcgaaaaa aagagtgtct tctgttactt ttcggctgtc gtagctgatg
    78241 ctatcaaaaa taactttgct gtagttgtag tggtaatgac cttggtcaat aatttcgcga
    78301 aaaaggccat ctttctttaa aatatctaat acggtttcaa tcttaatcat actttctatt
    78361 gtaaaccgaa agtcgtaaat ttacaagtaa caaggaaaag tttataatgg aagataagga
    78421 gtttttccta gctatcaaaa ttgaatgagg aatctatgtc gcacgaaaac aatcaccagc
    78481 aggcccagat gttacggggg actgcttggc taacggctag taactttatc agtcgcctac
    78541 tcggggctgt ttacattatc ccttggtaca tctggatggg ggcttatgca gctaaggcaa
    78601 atggtctctt taccatgggt tacaatatct atgcttggtt cttgttggtt tcaacagcgg
    78661 ggattccagt tgcggtggcc aagcaagttg ccaagtataa taccatgcga gaagaagagc
    78721 atagctttgc cctgattcgg agtttcttag gctttatgac aggactaggc ctggtttttg
    78781 ctttagtctt gtatgtcttt gctccttggc tagcagactt gtctggcgtg ggcaaagact
    78841 tgatcccaat catgcaaagc ttggcttggg gagtcttgat tttcccgtct atgagtgtta
    78901 tccgaggatt tttccaaggg atgaataacc tcaaacccta tgccatgagc caaattgctg
    78961 agcaggtcat tcgtgttatc tggatgctcc tagcaacctt tatcattatg aagctcggtt
    79021 caggagatta tctagcagcc gttacccaat caacctttgc tgcctttgtc ggtatggtag
    79081 ccagttttgc agtcttgatt tatttccttg cccaagaagg ttcactcaaa agagtctttg
    79141 aaacaggaga taagattaac agtaagcgtc tcttggttga taccattaag gaagccattc
    79201 cttttatcct gacagggtct gccatccagc tcttccagat tttggatcag ctgaccttta
    79261 tcaatagtat gagctggttt accaactaca gcaatgagga cttggttgtc atgttttctt
    79321 atttctcagc caatcctaat aaaatcacga tgattttgat ttctgtaggg gtttcgattg
    79381 ggagtgttgg tttgccactt ttgacggaaa actatgtcaa gggggacttg aaagcagctt
    79441 ctcgtctcgt tcaggacagt ctcaccctac tctttatgtt cttgctacca gcaacggttg
    79501 gagtggttat ggtaggagaa cctctatata cagtcttcta tggtaagcca gatagtttgg
    79561 ctctgggctt atttgtcttt gcagttttgc agtctattat tttaggcttg tacatggtct
    79621 tgtctccaat gcttcaggcc atgttccgca accgcaaggc cgttctctat tttatctatg
    79681 gttctattgc caagctagtc ttgcaactac ctaccatcgc cctcttccac agttatggtc
    79741 ctttgatttc aacaaccatt gctctcatca ttcctaacgt cttgatgtat cgggatattt
    79801 gtaaagtaac tggtgtcaag cgcaaggtga ttttgaagcg aactatttta atcagtttgc
    79861 tgaccctagt catgtttctg ttaataggaa ccatccagtg gctgttagga tttttcttcc
    79921 aaccaagtgg acgtttgtgg agcttctttt atgtagctct tgtcggtgcc atggggggtg
    79981 gactttatat ggttatgagt ctgcgtacct atttattaga taaggtaata ggaaaagccc
    80041 aagcagatcg cctgcgagca aaatttaagc tttcgtaagg tagcatttat aaataaaagg
    80101 aataagttga acaatctttt aggagaactt gaaacttatt ccttttttag cgtaaaaata
    80161 gctaaaatta tctttcaaaa atagaaaatg aggttttttt gattttttgg aaaaaacaat
    80221 tgactaaaca aaccaagagt tgtataataa aacaaatatt taaagcagga ggttccggaa
    80281 atgaaaaagt ctaagagcaa atatctaacc ttggcaggtc ttgtcctggg tacaggagtt
    80341 ttattgagcg cgtgtggaaa ttctagcacg gcgtcaaaaa cctacaacta tgtttattca
    80401 agtgatccat ctagcttgaa ctatctagca gaaaaccgcg cagcaacatc cgatattgtt
    80461 gcaaatttgg tagacgggtt attagaaaat gaccaatatg ggaatattat tccatcatta
    80521 gcagaggatt ggactgtttc tcaggacggt ttgacctata cctacaaact tcgtaaggat
    80581 gccaagtggt ttacttctga gggagaagaa tatgcgcctg taactgccca ggattttgtg
    80641 acaggtttgc aatatgcagc tgataaaaaa tcagaagcct tgtatctagt gcaggactct
    80701 gttgctggtt tggatgacta tatcactggt aaaacaagcg acttttcaac tgtcggtgtc
    80761 aaggcacttg atgaccaaac ggttcaatat actttggtta aaccagaact ttactggaat
    80821 tcaaaaacac ttgcaacgat actttttcct gttaatgcag atttcctgaa atcaaaaggg
    80881 gatgattttg ggaaggcgga tccatctagt attttgtaca atggaccttt cttgatgaaa
    80941 gcacttgtct caaaatctgc tattgaatat aagaaaaacc ctaattactg ggatgctaag
    81001 aatgtctttg tagacgatgt gaaattgacc tactatgatg gtagcgacca agaatcactg
    81061 gaacgtaatt ttacagctgg tgcttatact acggctcgtc tttttcctaa cagctccagc
    81121 tatgaaggga ttaaagaaaa atacaaaaac aatatcatct atagtatgca aaattcaact
    81181 tcatatttct ttaattttaa cctagatagg aagtcttaca attatacttc taaaacaagt
    81241 gacattgaaa agaaatcgac tcaggaagca gttctcaata aaaacttccg tcaggctatc
    81301 aattttgctt ttgacagaac atcttatggg gctcagtctg aagggaaaga aggtgcaaca
    81361 aagattttgc gtaacctagt ggttcctcca aactttgtca gtatcaaggg aaaagacttt
    81421 ggtgaagttg tagcctctaa gatggtcaac tatggtaagg aatggcaagg tatcaacttt
    81481 gcggatggtc aagaccctta ctacaatcct gagaaagcca aggctaagtt tgcggaagct
    81541 aagaaagaac tcgaagcaaa gggtgttcaa ttcccaatcc acttggataa gactgtggaa
    81601 gtaacagata aagtaggcat acaaggagtt agttctatca aacaatcaat tgaatctgtt
    81661 ttaggttctg ataatgtagt gattgacatt cagcaattaa catcagatga gtttgacagt
    81721 tcaggctact ttgctcaaac agctgctcag aaagactatg atttatatca tggcggttgg
    81781 ggacctgatt atcaagaccc gtcaacctat ctcgatattt ttaatactaa tagtggagga
    81841 gttctacaaa atcttggact agagcctgga gaagccaatg acaaggctaa ggcagttgga
    81901 ctggatgtct atactcaaat gttggaagaa gctaataaag agcaagatcc agccaaacgt
    81961 tatgagaaat atgctgatat tcaagcttgg ttgattgata gttctttagt tcttccaagt
    82021 gtttcgcgtg ggggaacacc atcattgaga agaaccgtac catttgctgc tgcctatggt
    82081 ttaaccggta caaaaggggt tgaatcatat aaatacttca aagtacaaga taagattgtc
    82141 acaacagacg aatatgcaaa agccagagaa aaatggttga aagaaaaaga agaatccaat
    82201 aaaaaagccc aagaagaatt ggcaaaacat gtcaaataaa atctaattgt agataagttt
    82261 gtgtaagaag tctttgtgct taaaaacgca taatatcagg tatataaaat cctagatgtt
    82321 atgcgttttg ttataggaag atttattaga ttttatcctc aaattgagtt attctcgact
    82381 ttatccgttg aaatattata aggagtattt atgaaattaa aattattaag agtagatact
    82441 aaggtgatta tggggagttt cttacttgtt ctgtctagtc tacttgcttt gttgcttccc
    82501 cttatcttaa agggtttaat agatgggagt tctattgaaa atataggttc caaagtattt
    82561 caatcgtttt tgatttttat tggtcaagcc ttgttttctt ctattggtta ctatctgttt
    82621 agtcaatcgg gtgaaaaaaa gatagcaaaa atcaggaaaa aagtgataga ggggttgatt
    82681 tatgcagaga aatccttctt tgataagagc caaagtgggg agttgacttc tgccattgtc
    82741 aatgacacga gtgtcattcg tgagttttta attacgactt tcccaaatat tattctgagt
    82801 ttagttatgg tacttggttc cattgtagtc ttatttagtc ttgattggaa tctttctcta
    82861 cttttattca tcactcttcc ttgtatgatg tttattatct tgcccctttc caatatcagt
    82921 gaaaagtata gtcgtcgttt acaggaggaa atcggatttt taacagggca attgactgaa
    82981 aagattcaag aacatgaatt aattaagact aaccaagcag agaaaagtgt acaggatgtt
    83041 ttggataatt gtattgaaag ggtacaaaac aattcactga aatcagatag ggttacttct
    83101 tttgagaccc cgtttgctct cttatttatc tttgcgacta tagttgtgat gctaacctat
    83161 gggggttatc gggtcagcgc aggatatata tctgtgggaa ccttggtttc gtttttgatt
    83221 tacctctttc aattacttaa tcctattagt aatatagcta attttgtaac tatttattct
    83281 aggagcaagg gatcttcagt tgcactggag aacttgcttg cagttcctaa agaaaaattt
    83341 gagtgaggaa aatcggtatc aggacaaggg ttgaatttta accatgtcta ttttggttat
    83401 gatgaaaatc gacctgtctt aaaggatatt acttgttcaa ttttcaaggg gcaaaaaatt
    83461 gcttttgttg gaccatctgg atcaggaaaa tcaacgattg tgcgtttgtt agagcggttt
    83521 tataaaccgc tttcaggata tattctaatg gagcaatcaa gtatatatga ttttaactta
    83581 aaagaatgga gaagtaaaat cgcttgggtt tcacaaaata atgcagtctt atctggcagt
    83641 attcgtgaca atctttgtct cggtttgaat cgcttagtaa ctgatgatga attgatgaaa
    83701 gtgctagact tagtatcact aggtgatgag attcgctcca tgaaagaggg actagatact
    83761 gaagttggtg aacgcggacg attcttgtca ggggggcaaa gccaaagact tcaaatagct
    83821 agaacctact taaaagatgc tgaaattctt atatttgatg aatccactgc taatcttgat
    83881 gcggattctg agtatgcgat tatcagtatc ctctattctg cattaaagga gaagacggtt
    83941 gtgattatag cgcatcgttt gtcaacggta aaagatgtgg attgtatttt cttcttagag
    84001 ggggggaaaa tcactggctc aggaactcat aaggaactac tggaaaatca tgagcgttat
    84061 gctcgttttg tgcaggagca aatgatagag tgaaggtgtc ttttgagatt caccatttta
    84121 tagtctatta aagggagcag gaaaaactcc ctttttatat agtttgaaac tataactagc
    84181 tcttgaaaag aagaaaatga gttgatgaaa ataagtggta caatagttac tatagatttg
    84241 gaggtattgt atgagcaagg aattacacat taacacaatt ttggctcagg cgggtattaa
    84301 gtcagatgaa gcgacaggtg cattggtgac accgcttcat ttttcaacga cctatcagca
    84361 tccagagttt ggtcgatcta ctgggtttga ctatacgcgc actaaaaatc caactcgtag
    84421 taaggctgag gaagtcttgg cggctattga gtcagcagac tatgccctag cgactagctc
    84481 agggatgtca gctattgtac tggcctttag cggctttcca gtaggaagta aggtcttggc
    84541 agtgcgtgat ctttacggtg gttcttttcg ctggtttaac caagtggagc aggaaggtcg
    84601 tttccatttt acctatgcca atacagaaga agagttgatt gctgagttag aaaaggatgt
    84661 ggatgttctc tatatcgaaa ccccaaccaa tcccttgatg ttggaatttg atatcgaaaa
    84721 actagcaaaa ttggctcatg ctaagggtgc caaagtggtg gtggacaata ccttctatag
    84781 ccctatctac caacgtccga ttgaagatgg agcagatatc gttctccatt cagcaaccaa
    84841 gtatctagca ggccacaatg atgtcttggc tggagtggtt gtgaccaata gtttagaact
    84901 atacgagaag cttttttaca atctcaatac aacaggggca gtcttgtctc catttgacag
    84961 ctaccagttg cttcgtggtc tcaagacctt gtctcttcgt atggagcgct caacagctaa
    85021 cgcccaagaa gtggttgcct ttttgaagga ttctccagca gttaaggaag ttctctacac
    85081 tggtcgtgga ggcatgattt cctttaaagt agccgatgaa acacgcattc ctcatatttt
    85141 gaacagtctc aaggtcttct cttttgcgga aagtttgggc ggagtggaaa gtcttattac
    85201 ttatccaacg actcaaactc atgctgatat tccagcagaa gtacgccatt cttatggttt
    85261 gacagatgac ctcttgcgtt tgtctattgg gattgaggat actagagatt tgattgcaga
    85321 tttgcgccaa gccttagaag gataagacaa agatgggaaa atatgatttt acaagcctgc
    85381 ccaaccgttt agggcaccat acctataaat ggaaagaaac agaaacggat agtgaagttc
    85441 taccagcttg gatagcggat atggactttg tggtcttgcc tgaaatccgc caagccgtgc
    85501 aaacttacgc agaccaactg gtttatggtt atacctatgc cagtgaagac ttaattaagg
    85561 aagttcaaaa gtgggaagct acacaatacg gttacaactt tgacaaagag gctcttgtct
    85621 ttatcgaggg tgtggtacca gccatctcaa cagctattca aacctttaca aaagaaggcg
    85681 aggcggtttt aattaacacg cctgtctacc caccctttgc tcgcagtgtc aagttgaata
    85741 atcgtagatt gattactaat tccttagtgg aaaaggatgg tctgtttgag attgactttg
    85801 accaacttga aaaggatttg gtggaagagg aggttaaact ctatattctt tgcaatcctc
    85861 acaatcctgg tggacgtgtt tgggaaaaag aagtgttgga gaagattggc caactctgcc
    85921 aaaaacacgg tgttttgtta gtttcggatg agattcacca agatttgacc ctctttggtc
    85981 acaaacacca gtctttcaat accatcaatc ctgccttcaa aaattttgct atcgtcttga
    86041 gcagtgccac taaaacattt aatattgctg gaacaaaaaa ttcctatgca gtcattgaaa
    86101 atcctaagtt gagactggct ttccagaaac gcctgttggc caataatcag catgaaattt
    86161 caggcttggg ttatttggcg acagaagctg cctatcgata cggtaaagat tggctagagg
    86221 aactcaagca agtctttgaa gaccacatca attatgtggt agatctattt ggaaaagaga
    86281 ctaaaatcaa ggtcatgaaa ccgcaaggta cctacttgat ttggcttgac ttttcagcct
    86341 atgacctgac tgatgaaaca ttgcaagagt tgttgagaaa tgaagccaag gttatcctca
    86401 accgtggttt ggattttgga gaggaaggaa gtctccatgc ccgcatcaat atagctatgc
    86461 ccaaatctct gttgcaggaa gtctgtcagc ggattgtggt tacttttgcc aaacgttaaa
    86521 aatccagtct tctaggagaa aagtcttcct agaaggctat tttcataggc gaaaatatgg
    86581 tataataaaa agataaggta aaggtgaaaa tatggctaaa ttgattccgg ggaaagttcg
    86641 tatcgaaggt gttgcccttt atgaaactgg taaggttgat atcatcaagg aaaagaacaa
    86701 tcggctctac gctcgcgttg cagaagaaga actgcgctat agtttagagg atgatttggt
    86761 tttttgtgcc tgtgattctt ttcaaaagag gggctactgt gtgcatttgg cagcgctaga
    86821 gcattttctg aaaaatgatg agcgtggtca ggaaatcttg tggagtctgg aagaaggtca
    86881 tgaagaaaaa gaggccgttg aaaccaaggt gaccttgggt ggcaagtttt tgaatcgaat
    86941 tttatctcca aaatcagaat gcgcctatga gttatcagct gtgggtcagg tggaagcagg
    87001 aaccaatcat atcttgtgga ctctgagaat cggccaaatc aatagccaaa aatactatgt
    87061 cattcgggat attccacttt ttttaaggat tgtcgagcag agaaagtcgt atatgattgg
    87121 caagatttat gaggagtctc tttcttggga agcctttgat gatgccagcc aagaactttt
    87181 gactttcttg cacggactaa cggaggaagg gctggttcca gacctctttt tccaaaacca
    87241 aggtcggcac ctctttttcc ctctgacctt ttttgagcag ggtgtgaatt tactgatggc
    87301 cttgccccat tttcaatttg accatcaagt ggatagctac caaaccctgc tttttcagga
    87361 tatgcatgct gatgccaatc tatttgcctt tacagtaaca gaatactcgg actattttga
    87421 aatggaaatc agtgagagtc ctagggtcaa tgtcttttat caaggagcag tacttttcca
    87481 taaaggtcag gtttattttt taacagacca gcagatgcgt cttctcaagg aaattaaagc
    87541 gttacctgtg ggtcaacaag gaaagaaata cctgcaattt gatagcagtg atcgagacaa
    87601 attggcctcc tgtctgactc tttttatcca gatgggcacc gtttcagctc cagaacgtct
    87661 acaaatcaaa acttttgcgc cctcttttta ctttgacagg gaagaagata atcggattcg
    87721 tttagaaatt cagtttgatt atggaaatag acaggtatct agccgacaag agctagaaga
    87781 attacccttt tcaagtgacg cggacttaga agaaagaatt ttccaagtct gtttggctgc
    87841 gggctttgaa gccgattttc aatcttggcg tcaggcctta aaagcggagt ctgtctatca
    87901 tttttttcat gatatcattc cagtctttga aaaactcggg catgttgacc tatcagataa
    87961 actagaagag ctttatagcc tagcgagtcc tcaggtgcag attgcctcca agggaggtct
    88021 cttggaaatc cagtttgatt ttcaaaatat tgcccaggag gaaatcgacc aagccatgca
    88081 ggccttggtt gccaatcagg atttttatat tgattcgtct aatcaagttt actttttcga
    88141 tgaagaaacc aagaaaattc gccaaaatct ccaggaactg gggcaatttg aattaaaaga
    88201 tggaaccttg caggctcgga aatccttggc ctacagttta gctcatctct ttgaagggcg
    88261 agaccgtgtt tctttttcac aagaattcca gaatctggcc caggatttga cgcatccaga
    88321 ggactttcct ttgcaagcaa ctcaggtcaa ggctgacttg cgagattatc aggaaaaggg
    88381 aattggctgg ttgcagatgc tccatcatta tggttttggt gggattttgg ctgatgatat
    88441 gggacttggg aaaacccttc agaccattgc ttttttgact agtcaagtga caaaagaaag
    88501 tcgagtcttg attctcgctc cgtcaggttt gatttacaac tgggcagatg agtttcagaa
    88561 atttgcccca cagttggatg tggttgttgt tcatggtttg aaagcaagtc gtgaggagat
    88621 tcttgccgag agccatcaaa tctatgtgac tagctatgcc accttccgtc aggacagtga
    88681 gttttatcag gggatggcct ttgacttcct tttcttagat gaggctcagg tcatgaaaaa
    88741 tgcccagacc aagattgccc agaccttgag acaatttgtg gtgccgtcgg tctttgcctt
    88801 gtcaggaact ccgattgaaa accatctggg tgagttgtgg tctattttcc aaatcgtcat
    88861 gcccggactt ttgccaagca agaaagaatt tatgaaattg ccagcagagc gagtggctca
    88921 gtttatcaag cctttcgtga tgcgacgcaa gaaagaagaa gttctgactg aattgccaga
    88981 cttgattgag gtggtttata aaaatgaact ggaagaccag caaaaggcta tttaccttgc
    89041 ccagttacaa cagatgcgag accatctggc tcaagtgtca gaacaggaat ttcagcgaag
    89101 tcgtgtggaa attttatctg gtttgatgcg cttgcgtcaa atatgtgaca ctcctgccct
    89161 gtttatggaa gattatcagg gagccagcgg caaactagat agtctccgag acctactgct
    89221 acaggtggca gacggcggac accgtgtctt gattttctct cagttcaagg gaatgttgga
    89281 aaaaattgaa caagaactgc cagacttggg cctgacttcc tttaaaatta cgggttcaac
    89341 cccagccaag gaaagacaag acatgaccaa ggcctttaat caaggagaaa gagatgcctt
    89401 tctgatttcc ctcaaggctg gtggggtcgg tctgaacctg acaggtgcag atacagtgat
    89461 cttggttgac ctttggtgga atcctgcggt ggaagcgcaa gccattggcc gtgcccatcg
    89521 gatgggtcag gaagaaacgg ttgaggtcta tcgcttggtg accaagggaa ccattgaaga
    89581 aaaaattcag gaactccaag aacaaaagaa acatctggtg tcacaagtat tggacggcac
    89641 agagtcacgt ggtagtctga ccctagcaga aattagagaa attttgggaa tttctgaagc
    89701 cagcacttga aaaatcaaga caatacgcta taatgaagtg ttgaaaggaa atagaaaatg
    89761 aaacaagaac gatttccatt ggtgtcagat gacgaggtca tgttgactga aatgccagtc
    89821 atgaatctct atgatgagtc tgatctgatc agtaatatca agggtgagta tcgagataaa
    89881 aattatttag aatgggctcc tattgctgaa gaaaaaccag tacaaccgat tgaaaagcaa
    89941 gtagggaaac ctaaaaaagc tcctttaggg gttaaaaaag aaggaaagag ctatgcggag
    90001 gtggcgcgtg aagaagcgcg tgcagacttg aaaaagaaac gctctgctaa ctatctaact
    90061 caggatttca gccttgcgag acgtcattct cagcccagtc tagttagaca gggcaatcaa
    90121 ccgacaactc ctttccaaaa ggaaaatcct ggtgaatttg tcaaatatag ccaaaaattg
    90181 acccagtctc attatatctt ggcggaagaa gttcattcta tccctaccaa gaatgaagaa
    90241 gtgtcagcac ctgctccaaa gaaaaacaat tatgattttc taaagaagag ccaaatctac
    90301 aataaaaaaa gtaaacaaac agaacaagaa cgtcgggttg cccaagagtt gaatctgacc
    90361 agaatgacag aataggggag aaaacatgtc aaagacatat cattttatcg gaattaaggg
    90421 atcagggatg agtgccttgg ccttgatgtt gcaccagatg gggcacaagg ttcagggatc
    90481 agatgttgaa aagtactact ttacccaacg cggtcttgag caggcaggaa ttaccattct
    90541 tccttttgat gaaaagaatc tagacggtga tatggaaatt atcgctggaa atgcctttcg
    90601 tccagataac aacgtcgaaa ttgcctatgc ggaccaaaat ggtatcagct acaaacgtta
    90661 ccatgagttt ctaggtagct ttatgcgtga ctttgttagc atgggagtag caggagcaca
    90721 tggaaaaact tcaacgacag gtatgttgtc tcatgtcttg tctcacatta cagataccag
    90781 cttcttgatt ggagatggga caggtcgtgg ttcggccaat gccaaatatt ttgtctttga
    90841 atctgacgaa tatgagcgtc acttcatgcc ttaccaccca gaatactcta ttatcaccaa
    90901 cattgacttt gaccatccag attatttcac aagtctcgag gatgttttta atgcctttaa
    90961 cgactatgcc aaacaaatca ccaagggtct ttttgtctat ggtgaagatg ctgaattgcg
    91021 taagattacg tctgatgcac caatttatta ttatggtttt gaagttgaag gcaatgactt
    91081 tgtagctagt gatcttcttc gttcaataac tggttcaacc ttcaccgttc atttccgtgg
    91141 acaaaacttg gggcaattcc acattccaac ctttggtcgt cacaatatca tgaatgcgac
    91201 agccgttatt ggtcttcttt acacagcagg atttgatttg aacttggtgc gtgagcactt
    91261 gaaaacattt gctggtgtta aacgtcgttt cactgagaaa attgtcaatg atacagtgat
    91321 tatcgatgac tttgcccacc atccaacaga aattattgcg accttggatg cggctcgtca
    91381 gaaataccca agcaaggaaa ttgtagcagt ctttcaaccg cataccttta caagaaccat
    91441 tgccttgttg gacgactttg cccatgcttt aaaccaagca gatgctgttt atctagcgca
    91501 aatttatggc tcggctcgtg aagtagatca tggtgacgtt aaggtagaag atctagccaa
    91561 caaaatcaac aaaaaacacc aagtgattac tgttgaaaat gtttctccgc tcctagacca
    91621 tgacaatgct gtttacgtct ttatgggagc aggagacatc caaacctatg aatactcatt
    91681 tgagcgtctc ttgtctaact tgacaagcaa tgttcaatag gatgttccca tggaaattcc
    91741 aattaagatc attcaggcaa gcaagtctga tttgcctgag ataggggcac ttcagacctc
    91801 gtcttttcca gctgaaaagc agcaactttc ccatatttta gaagaaagta tccgtaagtg
    91861 tgcggatacc tttcttctag ctagggatga aaatcaactt ttaggctata ttttatcaag
    91921 tccccagtca gacaatccgc aatatctaaa agtacattct ttagtcatcg agtctgacca
    91981 tcagagacag ggcttgggaa cacttcttct tgcagccttg aaagaggtgg cagttgagct
    92041 ggattacaaa gggattcgtt tggagagtcc tgatgagctg ctttcctatt ttgaaatgaa
    92101 cggttttgtt gatgaagaag caactttgct ctatgcaact agccagggct atagtatgat
    92161 ttggtttaat cccttttatc tggaggaaca atgaaaatca gacaagcaag attagaagat
    92221 ttggatcgga ttgttgaact tgaatttgaa aatttttcgg tcgaagaagc cattcctcct
    92281 tctgtctttg aagcacattt gagagaaatt cagacctctt ttctggttgc tgaaaaagaa
    92341 ggaagaatca tgggttatat cgaaggacca gttggcctgc accgccatct gcaagaccag
    92401 tcttttacag aagaaataaa agactatagt catgagcctg gtggttatat ctctgtgacc
    92461 tgtctgtcta ttgccaagga ggcacaggga ctcggactgg gtcagaaatt gctgacagcc
    92521 ttgaaagaag ttgctcttga agatgagaga gatggcatta atctaacctg tcatgactat
    92581 ctcatcgcct attatgaaaa acatggattt gtcaacgaag gccagtccca gtcaaccttt
    92641 gcaggggaaa catggtatga tatggtctgg gaaatgaaaa aataagttag gaaaagtatc
    92701 atagattgct ttttttggac ttttaagata taatattatg gattatcaac aaggaggaaa
    92761 aacttttgag tgaaaagtca agagaagaag agaaattaag ctttaaagag cagattctga
    92821 gagatttaga aaaagtaaaa ggctatgatg aagttctgaa agaagatgag gcagtagttc
    92881 gcactcctgc aaatgaacct tcagctgaag aactcatggc tgattccttg tcaacggtag
    92941 aggagattat gagaaaagct cctaccgtgc ctactcaccc aagtcaaggt gtaccagctt
    93001 ctccagcaga tgagattcaa agagaaactc ctggtgttcc aagtcatcca agtcaagatg
    93061 taccttcttc tccagcggaa gaaagtggat caagaccagg tccaggtcct gttagaccta
    93121 agaaacttga aagagaatac aatgaaaccc caacaagggt agctgtttcc tatacgacgg
    93181 cagagaaaaa agcagaacaa gcaggttcag aaacacctac gcctgctaca gaaacagtgg
    93241 atatcatcag cgatacatca cgtcgtagcc gtagagaagg agcaaaaccc gttaagccta
    93301 agaaagagaa gaagtcacat gtgaaagctt ttgtgatttc attccttgta ttccttgcct
    93361 tgctctcagc aggtggttac tttggttacc agtacgtgct agattctttg ttacctatcg
    93421 atgctaattc taagaaatat gtgacggttg gaattccaga aggttcaaac gttcaagaaa
    93481 tcggtacgac gcttgaaaaa gctggtttgg taaagcatgg tctgattttt agtttttatg
    93541 ccaagtataa aaattatacc gacttgaaag caggttacta caatttgcaa aagagtatga
    93601 gtacagaaga cttactcaaa gagttgcaaa aaggtggaac agatgaaccg caagaacctg
    93661 tacttgcgac tttgacaatt ccagaaggtt ataccttgga tcagattgct caagctgtgg
    93721 gtcaattgca aggtgacttc aaagagtctt tgacagcgga ggctttcttg gctaaagttc
    93781 aagatgagac gtttatcagt caagcagtag cgaaatatcc tactttactg gaaagtttgc
    93841 ctgtaaaaga cagcggtgcg cgttatcgtt tggaaggata ccttttccca gctacatact
    93901 ctatcaagga aagcacaact attgagagct tgattgatga gatgttagct gctatggata
    93961 agaacctatc tccttactat agtactatca aatctaaaaa tttgactgtc aatgagttgt
    94021 tgaccattgc ttccttggtc gaaaaagaag gtgccaagac agaagatcgt aagctcattg
    94081 caggtgtatt ctacaatcgt ttgaatcgtg atatgccact tcaaagtaat attgcaatct
    94141 tgtatgccca aggaaaactg gggcaaaata tcagtctagc tgaggatgtt gcgattgata
    94201 ccaacattga ttcaccttat aatgtttata aaaatgtagg tctcatgcct ggtccagtcg
    94261 atagtccaag tctggatgcg attgagtcaa gcatcaatca aactaagagc gataacctct
    94321 actttgtagc agatgtcaca gaaggcaagg tctactatgc taacaatcaa gaagaccacg
    94381 accgcaatgt cgctgaacat gtcaacagca aattaaacta aacaaactaa aattatgtga
    94441 tacttcacat aattttcttt agaaaatatt atcagaagaa agttgagaaa aatggcagaa
    94501 aaaacatatc ctatgaccct tgaggaaaag gaaaaacttg aaaaagaatt agaagaattg
    94561 aaattggttc gtcgaccaga agtggtagaa cgcattaaga ttgcccgttc atacggtgac
    94621 ctttcagaaa acagtgagta cgaagcagct aaggatgaac aagcctttgt cgaaggacaa
    94681 atctctagct tagaaacaaa aatccgctat gctgaaatcg tcaatagcga cgcagttgcc
    94741 caggacgaag tagcgattgg taaaacagtc accatccaag aaattggtga ggacgaagaa
    94801 gaagtttata ttatcgtagg ttcagctggt gcggatgcct ttgcaggtaa ggtttcaaat
    94861 gaaagcccaa ttgggcaggc cttgattggc aagaaaacag gtgatacagc aaccattgaa
    94921 acgcctgttg gtagctatga tgtaaaaatc ttgaaggttg aaaaaacagc ctaaaaacag
    94981 aaaaaggagt ggggaggcga tgtgcttcac tcactccttt ttccattttg ctactcttcg
    95041 aaaatctctt caaaccacgt cagcgtcgcc ttgccgtatg tatggttact gacttcgtca
    95101 gtttcctagt ttgctctttg attttcattg agtattagat gtataatgca ttgaagttaa
    95161 aatagtacac tttgatttct aagacattgt tagaaattag attaaattcc ttaatcgatt
    95221 tgcgcatgtt ttatttcatt tcattatacc ttagattgga aaataaggaa tcacataaat
    95281 cgcaagaaat agggaatctg attcgtgttt ataaccgttc aaaaagagaa gaggctgaaa
    95341 gtgagccact taatctttat gtcgaagatg aaaagggcaa tctccttgcg ggtttgatag
    95401 cagagacttt tggaaattgg ctagaaatcg agtatttgtt tgtaaaagag gaactgcgag
    95461 ggcaaggaat cggttcaaaa ctattgcaac aggcagaaag tgaagctaag aatcgaaatt
    95521 gttgttttgc ctttgtcaat acttaccagt tccaggcact ggacttttat cagaaacatg
    95581 gctacaagga agttttttct ttgcaagact atctctacat taggcaaaga tattattacc
    95641 aaaagaatct gtaaggcgag tatggaggtg gactgatgta tatgagtaac tatcgataaa
    95701 taccagttat aacctagaaa ttgtgtcttt ctagacgata ttgaggacaa tataatcgta
    95761 gccccaaaat taggaatcaa ggcttatcag gttaagaaaa gaagtgatgt tgttgatatt
    95821 ttaaaacaat ttatttaaac taaaaactct ctatcttttt aaattgacat taatccgaga
    95881 ttcccctctc ggattttgtg ttgctttcat taaatttaca ggtaagcctt gctagcttca
    95941 gtaaatatac acaagttttt cagaatagag tgaaatccaa aagaaaatgg aaataatgaa
    96001 agctcttgta ggcataagaa aacacctctg tgttatactt gttgttcaac cacaaacaca
    96061 agaaaggcac agagatgcaa aaccattata ctacaaaagg taaacatttg acaatcgata
    96121 gccgtcgctt aatcgaacga tggaaaaaag aaggaaaatc aaatagagaa attgcctctc
    96181 tgcttggaaa agttcctcaa actatccaca ctgaaatcaa gcgtgggaca gtccgacaat
    96241 gtcttggaaa agggcgcttc aaagaggttt attctgccga ctatgctcaa cagtcttatg
    96301 aaaacaatcg caagcgctcg gtcaggaaat taagcgtgac caaggaacta aaggaaaaga
    96361 ttctccacta tcataaccaa aaattttcgc ctgaaatgat ggtgatggct aaaggggtta
    96421 acgtgggaat ttcaaccatt tactattgga ttcatcatgg aaaattgggg ttaagcaaac
    96481 aggatctgct ttaccctaga aaaggaaaag cgcttaagaa acaggctagc atcaacttta
    96541 aacctgctgg tcaatccatc gcacagcggc ctgaagctat caatcttcgc ttggagaatg
    96601 ggcattatga gattgatacg gttctactta cgagagcgaa aaactactgc ttgcttgtct
    96661 tgacggatcg aaagagtaga catcagatca tccgattgat tccaaataaa agtgctgagg
    96721 tggtcaatca ggctctaaaa ctcatcttaa aacaacacaa gattctttcc atcacggcag
    96781 ataatggaac ggaattcaat cgcttgtttg atatattttc tgaggagcac atctattatg
    96841 cgcaccccta tgcctcttgg gaaaggggaa ctaatgagaa tcacaacagg ctcattcgta
    96901 gatagttacc taagggaacc aagaaaatga ctcccaaaga agtcgcattc atcgaaaagt
    96961 ggattaacaa ctatcctaaa aaatgcttgg actacaagtc acccagagaa gacttctgga
    97021 tggctaactt gaacttgaaa tttagcaaaa tggaaataat ttttattaaa cgcttccaat
    97081 agcggttaaa agttgacaaa tttaaatttt aggactacac taagtaagta aattttattt
    97141 taaaggagaa tttgttatga atttaacatt tttaggctta tgtattgcct gtatgggcgt
    97201 atctgtcggt gaaggtttat tgatgaatgg actgtttaaa tcagtagcac gccaaccaga
    97261 tatgctttct gagtttcgta gtttgatgtt tttaggtgtt gcctttattg aaggaacttt
    97321 ctttgtaact cttgtcttct catttattat caaataaata catggaacga gaagaaaagg
    97381 gaggatttta gatggaagaa agtattaatc caatcatctc tattggtcct gttatcttca
    97441 atctgactat gttagccatg actttgttga ttgtgggagt tatttttgtc tttatttatt
    97501 gggcaagccg caatatgacc ttgaaaccca aaggaaagca aaatatactt gagtatgtct
    97561 atgactttgt tattggattt acagaaccta acattggttc gcgctacatg aaagattact
    97621 cactcttttt cctttgttta ttccttttca tggtgattgc caataacctt ggcttaatga
    97681 caaagcttca aacgatcgat gggactaact ggtggagttc gccaaccgct aatttacagt
    97741 atgacttaac cttatctttt cttgtcattt tgttgacaca tatagaaagc gttcgtcgtc
    97801 gtggatttaa aaaaagtata aaatctttta tgagtcctgt ttttgtcata ccgatgaata
    97861 tcttggaaga atttacaaac ttcttatctt tggctttgcg gatttttggg aatatctttg
    97921 caggagaggt catgacgagt ttgttacttc ttctttccca ccaagctatt tattggtatc
    97981 cagtagcctt tggagctaat ttggcttgga ctgcattttc tgtctttatt tcctgcatcc
    98041 aagcttatgt ttttactctt ttgacatctg tgtatttagg gaataagatt aatattgaag
    98101 aggaatagaa aggagtaact gatgcacgta acagtaggtg aattaattgg taattttatt
    98161 ttaatcactg gctcttttat tcttttgcta gtcttgatta aaaaatttgc atggtctaat
    98221 attacaggca ttttcgaaga aagagctgaa aaaattgctt cagatattga tagagctgaa
    98281 gaagcccgtc aaaaagcaga agtattggct caaaaacgcg aagatgaatt ggctggtagc
    98341 cgtaaagaag ctaagacaat cattgaaaat gcaaaggaaa cagctgagca aagtaaggct
    98401 aatatcttag cagatgctaa actagaagca ggacacttaa aagaaaaagc caatcaagaa
    98461 attgctcaaa ataaagtaga agctttacag agtgttaagg gtgaggtcgc agatttgacc
    98521 atcagcttag ctggtaaaat catctcacaa aaccttgaca gtcatgccca taaagcactc
    98581 attgatcagt atatcgatca gctaggagaa gcttaatgga caagaaaaca gtaaaggtaa
    98641 ttgaaaaata cagcatgcct tttgtccaat tggtacttga aaaaggagaa gaagaccgta
    98701 tcttttcaga cttgactcaa atcaagcaag ttgttgaaaa aacaggtctg ccttcttttt
    98761 taaaacaagt ggcagtagac gagtcggata aggaaaaaac aattgctttt ttccaagatt
    98821 ctgtgtcgcc tttattacaa aactttatcc aggttctggc ctacaatcac agagcaaatc
    98881 ttttttatga tgtgcttgta gattgcttga accgacttga aaaagaaaca aatcgatttg
    98941 aagtgacgat tacgtctgct catcctctaa ctgatgaaca gaagactcgt ttgctccctt
    99001 tgattgagaa aaaaatgtct ctgaaagtaa ggagtgtaaa agaacaaatc gatgaaagtc
    99061 tcattggtgg ttttgtcatt tttgccaatc acaagacaat tgatgtgagt attaaacaac
    99121 aacttaaagt tgttaaagaa aatttgaaat agaaagtggt gttcttttgg caattaacgc
    99181 acaagaaatc agcgctttaa ttaagcaaca aattgaaaat ttcaaaccca attttgatgt
    99241 gactgaaaca ggtgttgtaa cctatatcgg ggacggtatc gcgcgtgctc atggccttga
    99301 aaatgtcatg agtggagagt tgttgaattt tgaaaacggc tcttatggta tggctcaaaa
    99361 cttggagtca acagacgttg gtattatcat cctaggtgac tttacagata tccgtgaagg
    99421 cgatacaatc cgccgtacag ggaaaatcat ggaagtccct gtaggtgaaa gtctgattgg
    99481 tcgtgttgtg gatccgcttg gtcgtccagt tgacggtctt ggagaaatcc acactgataa
    99541 aactcgtcca gtagaagcac cagctcctgg tgttatgcaa cgtaagtctg tttcagaacc
    99601 attgcaaact ggtttgaaag ctattgacgc ccttgtaccg attggtcgtg gtcaacgtga
    99661 gttgattatc ggtgaccgtc agacagggaa aacaaccatt gcgattgata caatcttgaa
    99721 ccaaaaagat caagatatga tctgtatcta cgtcgcgatt ggacaaaaag aatcaacagt
    99781 tcgtacgcaa gtagaaacac ttcgtcagta cggtgccttg gactacacaa tcgttgtgac
    99841 agcctctgct tcacaaccat ctccattgct cttcctagct ccttatactg gggttgctat
    99901 ggcggaagaa tttatgtatc aaggtaagca tgttttgatt gtatacgatg atctatcaaa
    99961 acaagcggta gcttatcgtg aactatcgct cttgcttcgt cgtcctccag gtcgtgaagc
   100021 cttcccaggg gatgttttct atctccacag ccgtttgctt gagcgctcag ctaaagtttc
   100081 tgatgaactt ggtggtggat caattacagc cctaccattt atcgagacac aagcaggaga
   100141 tatctcagcc tatatcgcaa ccaacgtgat ttctatcact gatggacaaa tcttccttgg
   100201 cgatggcctc ttcaatgcag gtattcgtcc agccatcgat gcgggttcat ctgtatctcg
   100261 tgtaggtggt tctgcacaaa tcaaagccat gaagaaggtt gctggtacac ttcgtatcga
   100321 ccttgcttca taccgtgagt tggaagcctt tactaagttt ggttctgact tggacgcagc
   100381 aacacaggct aagttgaacc gtggacgtcg taccgttgag gtcttgaaac aacctgttca
   100441 caaaccatta cctgttgaga aacaagtaac cattctttat gctttgacac atggtttctt
   100501 ggatactgtt ccagtagatg atattgttcg tttcgaggaa gagttccatg ccttctttga
   100561 tgctcaacat ccagagattt tggaaaccat tcgtgataca aaagacttgc cagaagaagc
   100621 agtcttggat gctgcgatta cagagtttct caatcaatct agcttccaat aagaatagag
   100681 gtgtcagatg gcagtgtctc taaatgatat taaaacaaaa atcgcctcaa caaaaaatac
   100741 gagtcaaatc actaatgcca tgcaaatggt atcggctgct aagttaggtc gctctgaaga
   100801 agctgctcgc aacttccaag tttacgctca gaaagtgcgt aaacttttga cagatatcct
   100861 tcatggtaat ggagctggtg cttcaactaa tccgatgttg attagccgtt ctgtgaagaa
   100921 gacaggctat atcgttatca cttcagaccg cggtttggtt ggaggttata attcctctat
   100981 tttgaaagct gttatggagt tgaaagaaga ataccaccca gacggtaaag gttttgaaat
   101041 gatctgtatc ggtgggatgg gagctgattt ctttaaggct cgcggtattc aaccacttta
   101101 tgaattacgt ggcttggcag accaacctag ctttgatcaa gttcgtaaga ttatttcaaa
   101161 aactgttgaa atgtaccaaa atgaactctt tgatgagctt tatgtttgct acaaccacca
   101221 tgtcaatacg ctaaccagtc aaatgcgtgt ggaacaaatg cttccgattg ttgacttgga
   101281 tccaaatgaa gcggatgaag agtacagctt gacttttgaa ttggaaacca gccgagaaga
   101341 aattctggag cagttgttgc ctcagtttgc agaaagtatg atttacggtg ccattatcga
   101401 tgccaagaca gctgagaatg ctgcgggtat gacagccatg caaacagcga cagataatgc
   101461 taagaaagtc atcaatgatt tgacaattca gtataaccgt gccagacagg cggcgattac
   101521 acaagaaatt acagaaatcg tagcaggtgc tagtgcctta gaataggctc tagtccagct
   101581 cgtatgaaaa tgaacttagg acctagttga gctaggaacc gacagtatct tatatagaat
   101641 aggagaagga gatgagttca ggtaaaattg ctcaggttat cggtcccgtt gtagacgttt
   101701 tgtttgcagc aggggaaaaa cttcctgaga ttaacaatgc acttgtcgtc tacaaaaatg
   101761 acgaaagaaa aacaaaaatc gtccttgaag tagccttgga gttaggagat ggtatggttc
   101821 gtactatcgc catggaatca acagatgggt tgactcgtgg aatggaagta ttggacacag
   101881 gtcgtccaat ctctgtacca gtaggtaaag aaactttggg acgtgtcttc aacgttttgg
   101941 gagataccat tgatttggaa gctcctttta cagaagacgc agagcgtcag ccaattcata
   102001 aaaaagctcc aacttttgat gagttgtcta cctcttctga aatccttgaa acagggatca
   102061 aggttattga ccttcttgcc ccttacctta aaggtggtaa agttggactt ttcggtggtg
   102121 ccggagttgg taaaaccgtc ttaatccaag aattgattca caacattgcc caagagcacg
   102181 gtggtatttc agtatttact ggtgttgggg aacgtactcg tgaggggaat gacctttact
   102241 gggaaatgaa agaatcaggc gttatcgaga aaacagccat ggtctttggt cagatgaatg
   102301 agccaccagg agcacgtatg cgtgttgccc ttactggttt gacaatcgct gaatacttcc
   102361 gtgatgtgga aggccaagac gtgcttctct ttatcgataa tatcttccgt ttcactcagg
   102421 ctggttcaga agtatctgcc cttttgggtc gtatgccatc agccgttggt taccaaccaa
   102481 cacttgctac ggaaatgggt caattgcaag aacgtatcac atcaaccaag aagggttctg
   102541 taacctctat ccaggctatc tatgtgccag cggatgacta tactgaccca gcgccagcaa
   102601 cagccttcgc tcacttggat tcaacaacaa acttggaacg taagttggta caattgggta
   102661 tctacccagc cgttgaccca cttgcttcaa gctcacgtgc cttggcacct gaaatcgttg
   102721 gagaagagca ctatgcagtt gctgctgaag taaaacgtgt ccttcaacgt taccatgaat
   102781 tgcaagatat cattgctatc cttggtatgg atgagctttc tgatgaagaa aagaccttgg
   102841 ttgctcgcgc ccgtcgtatc cagttcttct tgtcacaaaa cttcaacgtt gcggaacaat
   102901 ttactggtca gccaggttct tatgttccag ttgctgaaac tgtacgtggc tttaaggaaa
   102961 tccttgatgg taaatacgac cacttgccag aagatgcctt ccgtggtgta ggttctatcg
   103021 aagatgtgat tgcaaaagct gaaaaaatgg gattttaaga ggtgatctat ggctcagtta
   103081 actgtccaga tcgtgacacc agatggtctc gtctatgatc accatgccag ctatgtatcg
   103141 gttcgaactc tggatggtga gatggggatc ttgccacgac atgaaaatat gattgcggtt
   103201 ttagcagttg atgaagtaaa ggtaaaacgt atcgatgata aagatcacgt gaactggatt
   103261 gcagtaaacg gtggcgttat tgaaattgcc aatgatatga tcacaatcgt cgctgactct
   103321 gcagaacgtg ctcgtgatat cgatatcagt cgtgcagaac gtgccaaact tcgtgcagaa
   103381 cgtgcaattg aagaagcaca agacaaacat ttgattgacc aagaacgtcg tgctaagatt
   103441 gctttgcaac gtgctattaa ccgtattaat gtcggaaata gactataaga aaaaatgaac
   103501 ttgaaaatac caagttcatt ttttatggtg ttttaaggag caaaacggat gcagactgct
   103561 tcgggaacat ggaagtcgtt ggagagttct gctagacgac cattgtcaca attacgttta
   103621 aagacagttg cattgtcaga gtcttgatgg acaacaatga gaaatttttg gtcgggtgtc
   103681 aaatcaaaat cacgtggagt ctgaccatgc gttggaacga tttctaataa ctctaagcta
   103741 ccgtccgcaa ggatggtata tactgcgata gaatcatggc cacggttaga agcgtagagg
   103801 tatttaccgt ctttagagag atgaatagca gcggttccat taaagccttc gtaagcttct
   103861 ggtaaagttg aaataacctg catacgttca aattcgccaa cgccatcgta gattaaaact
   103921 tcgatagtac tattgagttc acaaatgaga taagcgattt tatagtggtt atggaaaatg
   103981 atatggcgtg agcctgctcc tggcttgctg tgataggtat agagcttaga taattttcct
   104041 tcttgatcga ggtcataggt gatgacttgg tcagttccca agtcgcaggt cactagatag
   104101 tggtcaggtg ttaaatctgt atagtgaaca tggggggaag cttgattttc atgtggacct
   104161 tggccactgt gttgatccat atcactaagt agaagactac catcttcctg gcgtttataa
   104221 acaaggactt gtcccttgtg atagttggct gcgtaaacca aatcacgctt ttcatcgaca
   104281 gcaacataac agtggggagc tccttcttca acaacatgat ttaacacagt cccgtcagtt
   104341 tgataggctg caattccccc cttatcgtct tggctaccaa cagtgtataa atgttggtgc
   104401 tggtcaaagg caaggtaggt tggacttggc tcagctgcaa aaagttctag atttgaaagc
   104461 tgaccagttt ctgtatcaaa gtctgccttg taaatccctt gagaagtacg acgtgtataa
   104521 gttccaaaat aaacagtttc tttcattact atacctctgt gtaaagataa gactattata
   104581 tcacaaaaac aagcaaatta aagacattca attagatgta agcactttaa aaaagagtta
   104641 ttttgtttca aaaatggtat aatgagagaa caatagaaag gaagtattta tggagcaaaa
   104701 agagaaacat tttagcctat cttggttttt caagtggttt ttagataaca aggcaattac
   104761 ggtattttta gtaaccttat tattgggatt gaatcttttt attttaagta agattagttt
   104821 tctattttca cctgttttag actttatagc agttgtgatg ttgccagtca ttttgtctgg
   104881 tttgttatat tatttgttga atcctattgt tgattggatg gagaagcata aggttaatcg
   104941 tgttatagct atcactattg tctttgttat catcgctctc tttatcattt ggggcttggc
   105001 agtcgccatt ccaaatctgc aacgtcaggt tttgaccttt gcaagaaacg ttcctgttta
   105061 cttagaagat atagatagga ttgttaatgg attggtagcc cagcacctgc cagatgattt
   105121 cagacctcaa ttagagcaag ttttgaccaa tttttctagc caggctacag ttttggcaag
   105181 taaggtttca tctcaggcag tcaactgggt gagtgccttt attagcggag cttctcaagt
   105241 gattgttgcc ttgattatcg ttcctttcat gctcttttat ctcttgcgtg atgggaaagg
   105301 cttgcgtaac tatttgaccc aattcattcc aagaaaattg aaggaacctg ttggacaagt
   105361 tctatcagat gtgaatcaac agttgtccaa ctatgttcga gggcaagtga cagtggctat
   105421 tattgtagca gtaatgttta tcatcttctt caagattatt ggtctacgct atgcggttac
   105481 gctgggggtt actgctggta ttttaaatct ggtcccttat cttggtagct ttctagccat
   105541 gcttcctgcc ctagtattgg gtttgattgc tggtccagtc atgcttttga aagtagtgat
   105601 tgtctttatt gtagaacaaa ctattgaagg ccgttttgtc tctccattga ttttgggaag
   105661 tcaattaaac atccatccta ttaatgttct ctttgttttg ttaacttcag gatctatgtt
   105721 tggtatctgg ggagttttac ttggtattcc ggtttatgcc tctgctaagg ttgtcatttc
   105781 agccattttc gaatggtata aggtagtcag tggtctatat gaattagagg gtgaggaagt
   105841 caagagtgaa caatagtcaa cagatgttac aggctttgga ggagcaagat ttaactaagg
   105901 ctgagcatta tttcgccaaa gctttagaaa atgattcaag tgatcttctg tatgagttgg
   105961 caacttatct tgaagggatt ggtttctatc ctcaggccaa ggaaatttac ctgaaaattg
   106021 tagaggattt tccagaggtt catcttaatc tagctgcaat tgctagcgag gatggtcaaa
   106081 tagaagaagc ctttacctat cttgaggaaa tccaagctga cagtgactgg tatgtctcgt
   106141 ctttggctct gaaggcagac ctttaccagc tggaaggttt gacagatgtg gcacgtgaga
   106201 aattattgga ggccttgacc tactcagagg attctctctt gatattgggt ttggcagagt
   106261 tggatagtga gttggaaaat taccaagcgg ctattcaagc ctatgcccag ttagataatc
   106321 gctcgattta tgagcaaacg ggcatttcca cctatcaacg aattggcttt gcctatgctc
   106381 agttagggaa atttgaaacg gctactgagt ttttagaaaa agccctggag ttagaatacg
   106441 atgacttaac agcttttgag ttggccagtc tttattttga tcaagaagaa tatcaaaaag
   106501 ccaccctcta ctttaagcag cttgatacca tttctcctga ctttgaaggc tatgagtatg
   106561 ggtacagtca ggctttacat aaggaacatc aagttcaaga agccctgcgt atcgctaagc
   106621 aaggattaga gaaaaatccc tttgaaactc gcctcttgct agctgcttca caattttctt
   106681 atgaattgca tgatgctagt ggtgcagaaa attatctcct tactgcaaaa gaagacgctg
   106741 aggatacaga agaaatcttg cttcgtttag ccactattta tctggagcag gagcgttatg
   106801 aggatattct agacttgcag agtgaggagc cagaaaatct tttgaccaag tggatgattg
   106861 ctcgttctta tcaagaaatg gacgatttgg atactgctta tgagcattat caagagttga
   106921 caggagattt gaaggacaat ccagaatttc tggaacacta tatctatctc ttgcgtgaat
   106981 tgggacattt tgaagaagca aaagtccatg ctcacactta cttaaaactg gttccagatg
   107041 atgtgcaaat gcaagaactg tttgagagat tgtaagaatg tttaaacata tagaactgta
   107101 gtttatctct tttgatagct acggttttta tttgtatatg gtagaatctt tttacaaaaa
   107161 tacttggtaa tcttgtttat tcatgctata ataggaacaa ttacttttag gaggtgcagt
   107221 atgtcttatt tatttgagat attaccgagt ttactgaatg gtgcgagcac gactgtacag
   107281 gtctttgcac tggtcttgct attttcgatt cccttgggcg ttttgattgc ctttgccttg
   107341 caagtccatt ggaagcccct ccattatctg attaacattt acatctgggt tatgcgagga
   107401 acccccttac tcttgcaact gatttttatc tattatgtgc tcccaagtat tgggattcgt
   107461 ttagaccgcc ttcctgcagc tattattgcc tttgttttga attatgcggc ttactttgca
   107521 gaaattttcc gtgggggaat tgacactatt ccaagaggac agtatgaggc tgccaaggtc
   107581 ttgaagttta gcccttttga cagagtgcgc tatattatct tgccccaagt gaccaagatc
   107641 gttcttccta gtgtctttaa tgaagttatg agtttggtca aggatacttc tttggtctat
   107701 gctctcggaa tttcagacct tatcttggct agtcgaacag ctgctaaccg cgatgctagt
   107761 ctggttccta tgttcttggc aggagccatt tatttgattt tgattgggat tgtgacaatt
   107821 atttccaaaa aagttgagaa gaagtatagt tattatagat aggaggctgc catgttagaa
   107881 ttacgaaata tcaataaagt ctttggagac aaacaaatcc tgtctaattt cagtctaagt
   107941 attcctgaaa agcaaatcct ggctatcgtt ggaccttctg gtggaggtaa gacaactctt
   108001 ttacgtatgc ttgcaggtct tgaaaccatt gattcagggc aaatctttta taatggacaa
   108061 cctttagagc tggatgaatt gcagaagcgc aacctactgg gatttgtctt ccaagatttt
   108121 caactatttc ctcatctatc agttctggaa aatttgactt tatcgcctgt gaagaccatg
   108181 ggaatgaagc aggaagaggc tgagaagaag gcgagtggac tcttggaaca gttaggacta
   108241 ggaggacacg cagaggccta tcctttctca ctatctggtg ggcaaaagca gcgagtggct
   108301 ttggcgcgtg ctatgatgat tgacccagaa atcattggct acgatgaacc aacttctgcc
   108361 ctggatccag aattacgttt ggaagtggag aagctaatct tgcaaaatag ggaacttggg
   108421 atgacccaga ttgtggttac ccatgatttg cagtttgctg aaaatatcgc agatgtatta
   108481 ttgaaagtag aacctaaata ggaggaaaaa tggatgaaaa aatggatgct tgtattagtc
   108541 agtctgatga ctgctttgtt cttagtagct tgtgggaaaa attctagcga aactagtgga
   108601 gataattggt caaagtacca gtctaacaag tctattacta ttggatttga tagtactttt
   108661 gttccaatgg gatttgctca gaaagatggt tcttatgcag gatttgatat tgatttagct
   108721 acagctgttt ttgaaaaata cggaatcacg gtaaattggc aaccgattga ttgggatttg
   108781 aaagaagctg aattgacaaa aggaacgatt gatctgattt ggaatggcta ttccgctaca
   108841 gacgaacgcc gtgaaaaggt ggctttcagt aactcatata tgaagaatga gcaggtattg
   108901 gttacgaaga aatcatctgg tatcacgact gcaaaggata tgactggaaa gacattagga
   108961 gctcaagctg gttcatctgg ttatgcggac tttgaagcaa atccagaact tttgaagaat
   109021 attgtcgcta ataaggaagc gaatcaatac caaaccttta atgaagcctt gattgatttg
   109081 aaaaacgatc gaattgatgg tctattgatt gaccgtgtct atgcaaacta ttatttagaa
   109141 gcagaaggtg ttttaaacga ttataatgtc tttacagttg gactagaaac agaagctttt
   109201 gcggttggag cccgtaagga agatacaacc ttggttaaga agataaatga agctttttct
   109261 agtctttaca aggacggcaa gttccaagaa atcagccaaa aatggtttgg agaagatgta
   109321 gcaaccaaag aagtaaaaga aggacagtaa gataaaatag tggctgagac tacgttttga
   109381 ttagcaaaac gtagtttttt ttgtaatcta ggaaaacgat aatagcgatt gaatctggat
   109441 aattgaatat ggaatagccc actgtgattt ctaaaacatt gttaaaaatt gatttgactt
   109501 ccaaaattaa aatgttctgt aatgaaatac tgatgtaact gttttaggaa caataaaacg
   109561 cataatatca aggtttttgc accttacatt atgcgttttt gtgattttaa gacttgttag
   109621 ctgatttttt acaatcctac gaaatctttg atttcttgtg ctgacattga agagtcgcaa
   109681 cggacgttga tttgtccatc tgtaatatga acaaaacctg gtacagttgg gattccataa
   109741 cgtgagcgga atgcttgcaa atcattgagt tggcttggtt cttcactatt gatgaagtaa
   109801 atgtgagctt tggtttcagc tacgacacct gacaatgtac ctgcaaattt acggcagtaa
   109861 gggcaagttt tgcgaccgat aaagaaggtt gcagtttctt ttttatcaag agcttcttgc
   109921 gcacgcacaa ctgtagtgac ttcaaggtct ttgatgttat ctaaaaattg ttccatgaga
   109981 ttacctcgct ttcattgata agtctagtat gccataaagt ttctaaaatt gcttagattt
   110041 gatacgaaaa aagatgaggt tggttggtct catcttttat aggtctttat tttacaaatg
   110101 cattgatttc tgcttcgatg ttagtaatct tagcttgtga ttcttcgttg gtttccccta
   110161 caactgcaat gtagaacttg atttttggtt ctgtacctga agggcgaacg gcaatccatg
   110221 aaccgtcagc aagtgtgtat ttcaacacat cacttggagg agttgtcaag tttgtaacag
   110281 taccgtcagc aacagtagca gtttgtgcct tgaagtcttc tacgacagtg atagctgttg
   110341 cgttccattc tgttggagca ttgttgcgga atttagccat aatcgctttg atttgttcag
   110401 caccatcgac acctgaaaga gtaacagaga ttgttttttc tgcgtagtag ccatattctt
   110461 tatagatttc ttcgataccg tcagcaagtg tcaaaccacg agaacggtag taggcagcaa
   110521 gttcagcaac tacaagaacg gcttggatgg catctttatc acgtacaaat ggtttaatca
   110581 agtaaccgaa gctttcttca aatcccatca tgtaagtgtg gttgtgtttt tcttcgaatt
   110641 cttggatttt ttcagcgata aatttgaaac ctgtcaagac gttgaacata gttgcgccgt
   110701 agctttcagc aatcttcgtt accaagtcag ttgaaacgat agatttgcag agagcggcat
   110761 tttcaggaag agttccagcg tttttgtgag cttccaagat gtatttagcc atgatagcac
   110821 cgatttggtt acctgaaagg ttgaggtagc tgccatcttt ttgaagaact tcaacaccaa
   110881 cacggtcagc gtctgggtca gttgcgacaa gaacatctgc accaacttga cgaccaagtt
   110941 cttcagcaag ggcaaaggct gcttggcttt ctgggtttgg agatgttaca gttgagaagt
   111001 ctgggtcagc agttgcttgc gcttcaacaa cttgaacaga gtcaaatcct gcttgggcaa
   111061 gagcacgacg agccaacatt tcaccagtac catgaagtgg tgtgtagaca atcttcatgt
   111121 ctttaccaaa ttcttcaatc aaggctgggt tgatgtttat gtccttaacc tctttaaggt
   111181 attctatgtc aacagcttcg ccgataactt caatcaagcc agaagctttt tcagtttcca
   111241 catcagcaac ttcaactgca aatgggtttt cgattgcacg gatataagta gtcaaagcgt
   111301 ccgcatcgtg tggaggcatt tgtccaccgt cttcaccgta aaccttgtaa ccgttaaatg
   111361 gagcagggtt gtggctggct gtgaccatga tacctgcgaa acagttgaga tgacgaactg
   111421 caaatgatag ttctggagtt ggacgaaggc tttcaaatac gtaagatttg atgccgtgtt
   111481 tagcaagaac tgccgcagat tcaaaggcaa actcaggtga gaagtgacgg ctatcgtagg
   111541 caattgctac accgcgttct ttctcgtttc caccttttga ctcaatcaaa cgagccaatc
   111601 cttcagtagc ttggcgaaca acgtagatgt tgatacggtt tgtaccagca ccaaccaagc
   111661 cacgcatacc tgcagtacca aattcaagat ttgtatagaa ggcatcttcc ttagtttttt
   111721 cgtccatatt ttccaaatct tgacgaaggt agtcaggaag ctccacaaaa tcaacccatt
   111781 tctggtaatt ttcttggtaa gacattcaaa ttctccttta tttttaaaac atttaatcag
   111841 tttgattata tcattttttt tagttttagt aaaaccttat ctgcttcgaa aatctcttca
   111901 aaccaggtca gattgaattt tggggttata tgatgtttag gctaggaaaa attcaatttc
   111961 agtaaaaaaa gtaagtcttc tcataacaaa acattgatat agttacttag ttttaaacaa
   112021 gcatattata ataaagctat ggcatatagt actgatttta aacagcgagc attagattac
   112081 atcaaagagg ggcacagcca tgtcgaggca gccaagtttt ttggtgttgg cgtcagaact
   112141 ctcttcacgt gggaaaagaa agacgtgaac aagaacacat agagaggaaa aagcgagtcg
   112201 tcaaaaaccg aaagattcct ttagaggaat tgaaagcctt tgtagaggct catccagatg
   112261 cttttttacg ggaaattgcg gcacattttg attgtgctgt tccttcagta tgggcagctt
   112321 taaagcagat taaggtcact ttaaaaaaag atgacgagct ttaaggaaca agacccagaa
   112381 aagtagcctt atttcttaag aattttaata gtttaaagca cctagcacct gtttatattg
   112441 atgaaacagg aatcgaccgc tatctctatc gtccttatgc aggggctcct agaggggaga
   112501 aagtctatga aaagattagc ggacgtcgtt ttgagcgaat ttcaattgtt gcaggacaag
   112561 tagacggaga gtttatagct cccatgattt acaagaaaag catgacaagc gatttctttg
   112621 tggagtggtt caaaacgcaa ctcctacctg ctttgaagac acctcatgtt attgtcatgg
   112681 gcaatgctgg ttttcatccc aagaacattt tggatgaact ctgcatccaa gataaacact
   112741 ttttcttacc tctaccacct tattcaccgg atttgaatcc tattgagcaa gcttgggcta
   112801 tcttgaaaaa gaaagtgacg gatttattaa gggaagttcc aactattttt gaatgtttgg
   112861 aatgcttttt taaaactaga tgactataac ggttctaaag gaacctatcg agtagtcatt
   112921 aaaactaagg atactgctgg ttaagagaag acggtataca atcaaaccat tcaccgtgta
   112981 gccgaaatcg ttcagaatga agacttgtat aaaaaaggtt tgaatgttga acttgcgcac
   113041 caacaaatta agggattttt tgaagcagag tttaaaaatc gtattaatgg agttcttaat
   113101 actaaaataa aaaatagtac attaaatcgt gtaaataaaa aaactataca ccagagcaac
   113161 aaaaactcca tgatcaattt gaagcagaag caacggaaga tgctaaaaaa caaggcgata
   113221 ttgtgttgaa tgttgaccag gatttcatga gcatatctaa gtctaataaa agtggttcag
   113281 actggaagaa aactttcaca gtgaggacaa ccaataggct agcaaatgac ttgaataatg
   113341 tcttgaaaca ggctgataaa gatactccta ataccccaac ttggctaaac tcagctgctt
   113401 ctaaagctaa agatgatgac agagcatata aactactgaa gactcttata ccaggagaaa
   113461 attacctatc atgttaagga taatcagcta gaagtagaaa cagataaata cacatatact
   113521 gccgctagaa atggtagtaa ggaagttggt attcaagagt cagatatagc agcaactcta
   113581 agtgccgatg aatataattc taatcgccaa acttttgaga gagaatacaa atacaaaagc
   113641 aaatgccctt aataatggtt gggctagatc tggttctgaa gagttcaaaa agttctccca
   113701 ctttgtaggg gtagacaaag ggattgtgcg aacgaatgta ctgactggta aaaaactatc
   113761 tgataagatt aggaaagaag tgggctctgg agatagcaaa ctaggaaaag gcggctattt
   113821 ctctactggg gatgttctat taggaaaaga tgttgtttct tataccgtac aagtattttc
   113881 agagaataat gaaagagtag gagtaaacac tcaaagtcac cgtgttcagt ataatctccc
   113941 aattctagct gacttttcag tcatccaaga tactgtggaa ccatcacgaa ccgttgttga
   114001 aaaaatcatt ccaaaactaa atattcccga agaagagaaa gggaaaataa ccgaagaaat
   114061 caagaaaaag aaaaaaacct cagaattggc agaactaatc tcagaaaatg tgaaagttcg
   114121 ctatgttgat gaacaagggc gtttgctatc attgaaaaat gatactggaa ttggagaaaa
   114181 agaaagtgac ggaacctaca ttaccaataa aaaacaactg attggtacca gctacaatgt
   114241 cacagataaa aaactcagta gcatgactac tactgacgga aaatattata cttttaaaga
   114301 agcagataca aattctgcaa gtttaactgg gaatattgta agcgaaggta gaacagtgac
   114361 cttagtttat agagaaagcg aagcgccaac cactgctaca gtaacagcca attactataa
   114421 agaaggtagg caagagaagt tggtagagtc tgttataaaa gctgatttag cgataggttc
   114481 tgagtatacc acagaatcaa aaactattga agggaaaaca acaactgagg acaaagaaga
   114541 ccgagttatc acaaggaaaa caacatacac cttggtagca actcctgcaa atgcgtacca
   114601 gaagacggtg caacagttga ctattactac cgtgagaatg ttgaggaaac agtggttccc
   114661 aaaacagcaa cctctactga gacgaagact ataacgcgta tcattcatta cgttgataaa
   114721 gttacgaacc aaaatgtaaa agaagatgtt gttcaacctg taaccttaag ccgtacaaaa
   114781 actgagaaca aggtcacggg agttgtaacc tacggtgaat ggacaacagg aaactgggac
   114841 gaggttatat ctggtaagat tgacaagtac aaagatccag atattccaac agttgaatca
   114901 caagaagtta cgtcagactc tagtgataaa gaaataacgg taaggtatga ccgtttatca
   114961 acaccagaaa aaccaatccc acaaccaaat ccagagcatc caagtgttcc gacaccaaac
   115021 ccagaactac caaatcaaga gactccaaca ccagataaac caactccaga accaggtact
   115081 ccaaaaactg aaactccagt gaatccagac ccagaagttc cgacttatga gacaggtaag
   115141 agagaggaat tgccaaacac aggtacagaa gctaatgcta ccttggctag tgctggtatc
   115201 atgaccttgt tagctggtct aggattagga tttttcaaga aaaaagaaga tgaaaaataa
   115261 tagattttag aatctaggaa ccaggaaaag ctcacagatg tgggcttttt tcctggtttt
   115321 gagaacgagg tctttcgtaa agaataaaaa cgcttacaag tctgttgaac tgggaaacta
   115381 tgaatcctat ttttttaaaa atatttccag aaatcagttg ctaaataggg taaaaattga
   115441 taaaataagg aatatctaaa aaattttaag gagaatctag caaatggatt tcacatgggc
   115501 actgaagtat gccactgaat ttttgggaac tgccattttg atcattcttg ggaatggtgc
   115561 agttgccaac gttgaactta aaggtacgaa aggtcaccaa agtggctgga tcgtcatcgc
   115621 tgttggttat ggtatggggg ttatgatccc agccttgatg tttggtaacg tatctgggaa
   115681 tcacatcaac cctgctttca ctctagggct tgcagttagc ggtcttttcc cttgggcaca
   115741 agtggtacct tacattatcg cgcaagtctt gggggctatc tttggccaag ccttagttgt
   115801 ggcaacatac cgtccattct acttgaaaac tgaaaaccca aataacatct tgggaacttt
   115861 ctcaactatt tcaagtattg accatggtac aaaagaaagt cgctatgcag caactgtcaa
   115921 tggtttgatt aatgagtttg ttggttcatt tgttttgttc tttgcagctc ttggtttgac
   115981 taaaaacttc tttggtgctg aagtgcttca attcatgaaa caaaaggcaa tagaagcagg
   116041 acaaacagtt gatttttctg acttggctat taaagcacag gtggctccac acactgcttc
   116101 aggactttct gtggctcact tggcacttgg attcctcgtt atggctttgg taacatcact
   116161 tggaggacct acaggacctg ccttgaaccc agcccgtgac ttgggaccac gtctccttca
   116221 tgctttcctt ccaaaatcag ttcttggtga gcataaaggc gattcaaaat ggtggtattc
   116281 ttgggtacca gtagtagcac ctatcgcagc agcaattgcg gcagtagctg tattcaaatt
   116341 cctttatctc taagaaatag ctcctttaac atttgagtga gcaccatcta taagtaagag
   116401 aggatcagac tggttctctc tttttgattt tttagggaaa tgaaagaaac tctaaacaaa
   116461 ctcctctcca gcagtggttt agaagtctca gtgggctatt ccagcttcaa tgggctatag
   116521 taggttgcag ttgaaataat agacccttgt ttctaaaaca ttgttagaaa ttggtttgaa
   116581 ttctccaatc aaattgtgca gttttcattc tactatatat tatcggagat gggttcccta
   116641 tcttgtaagt ctgctttata gtgggttgaa gttggaatag tcctcccttc tttctcaaac
   116701 attgtgagga attgatttac cttcctcaac aaaatgttca gtttctattt cattttgcta
   116761 taaaataagc gattaggggg gctattcttc gacctacatt gactctgctg agtcctatga
   116821 ttgttatcgt tttatctgca attttatact caatgaaaat caaagggcaa actaagaagc
   116881 tagccgcagg ttgttcaaaa cacagttttg aggttgtata gtagattgaa actagaatag
   116941 tacaccttaa cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgccc
   117001 tattcttgtt tcattttact atataaacca gagactgttt acattttcag caagtgagtg
   117061 gatggataat gctgaaaact ccttgaagga taagtctatt tagtactttc tattagttag
   117121 ttaaattttt accaagaata attcacaaaa acgttgtaaa acacttgcaa tttagctgaa
   117181 atttgataaa atagtaagga aagttagact gtattgccta ctgtctatct ataaaatata
   117241 ttttattgga ggcttttact caaatggcaa aagaaaaata cgatcgtagt aaaccacacg
   117301 ttaacattgg tactatcgga cacgttgacc acggtaaaac taccctaact gcagctatca
   117361 caactgtttt ggcacgtcgc ttgccttcat cagttaacca acctaaagac tatgcgtcta
   117421 tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat caacactgcg cacgttgagt
   117481 acgaaactga aaaacgtcac tacgctcaca tcgacgctcc aggacacgcg gactacgtta
   117541 aaaacatgat cactggtgct gctcaaatgg acggagctat ccttgtagta gcttcaactg
   117601 acggaccaat gccacaaact cgtgagcaca tccttctttc acgtcaggtt ggtgttaaac
   117661 accttatcgt cttcatgaac aaagttgact tggttgacga cgaagaattg cttgaattgg
   117721 ttgaaatgga aatccgtgac ctattgtcag aatacgactt cccaggtgac gatcttccag
   117781 ttatccaagg ttcagcactt aaagctcttg aaggtgactc taaatacgaa gacatcgtta
   117841 tggaattgat gaacacagtt gatgagtata tcccagaacc agaacgtgac actgacaaac
   117901 cattgcttct tccagtcgag gacgtattct caatcactgg acgtggtaca gttgcttcag
   117961 gacgtatcga ccgtggtatc gttaaagtca acgacgaaat cgaaatcgtt ggtatcaaag
   118021 aagaaactca aaaagcagtt gttactggtg ttgaaatgtt ccgtaaacaa cttgacgaag
   118081 gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt tcaacgtgat gaaatcgaac
   118141 gtggacaagt tatcgctaaa ccaggttcaa tcaacccaca cactaaattc aaaggtgaag
   118201 tctacatcct tactaaagaa gaaggtggac gtcacactcc attcttcaac aactaccgtc
   118261 cacaattcta cttccgtact actgacgtta caggttcaat cgaacttcca gcaggtactg
   118321 aaatggtaat gcctggtgat aacgtgacaa tcgatgttga gttgattcac ccaatcgccg
   118381 tagaacaagg tactacattc tctatccgtg agggtggacg tactgttggt tcaggtatgg
   118441 ttacagaaat cgaagcttaa ttcgatttag ttcccagaag aacaattatt taagtcagac
   118501 actaaaagaa tcttgcttgg caaggttctt tttttagata ttgaactaat actaaatgaa
   118561 aatcaaagag caaactataa tatattgaaa ctagaatagt acacatctac ttctaaaaca
   118621 ttcttagaaa tcgatttgat tgtcttgatt gatttgtctt gttcttattt cattttgtta
   118681 tagaaagtta gctgcagact gctcaaaaca ctgtttttag gttgtagata gaactgacga
   118741 agtcagtaac atctatacga caaggcgaag ctgacgcggt ttgaagagat tttcgaagag
   118801 tataatacta gactcaaatc aaaaagcatt atacaatagt aatatgaaat caactaaaga
   118861 agaaatccaa accatcaaaa cacttttaaa agactctcgt acagctaaat atcataaacg
   118921 ccttcaaatc gttctatagt aaaatgaaac aagaacagga caaatcgatt aggacagt
//
LOCUS       DAVKUR010000002        98005 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKUR010000002 DAVKUR010000000
VERSION     DAVKUR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 98005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.002"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..560
                     /locus_tag="VW749_000140"
     CDS             <1..560
                     /locus_tag="VW749_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174252.1"
                     /translation="ELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYC
                     LLDNSLTLKNDWNYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEG
                     KKEYEMFFQWLNFFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGL
                     SYYLMKFLLKSFSNEYLKTTDEVNR"
     gene            557..1735
                     /locus_tag="VW749_000141"
     CDS             557..1735
                     /locus_tag="VW749_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0174253.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            2160..2393
                     /locus_tag="VW749_000142"
     CDS             2160..2393
                     /locus_tag="VW749_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0174254.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            2676..4625
                     /gene="mutL"
                     /locus_tag="VW749_000143"
     CDS             2676..4625
                     /gene="mutL"
                     /locus_tag="VW749_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0174255.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(4950..5417)
                     /locus_tag="VW749_000144"
     CDS             complement(4950..5417)
                     /locus_tag="VW749_000144"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0174256.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIAVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(5418..6623)
                     /locus_tag="VW749_000145"
     CDS             complement(5418..6623)
                     /locus_tag="VW749_000145"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0174257.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(6643..7278)
                     /gene="ribE"
                     /locus_tag="VW749_000146"
     CDS             complement(6643..7278)
                     /gene="ribE"
                     /locus_tag="VW749_000146"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0174258.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(7263..8363)
                     /gene="ribD"
                     /locus_tag="VW749_000147"
     CDS             complement(7263..8363)
                     /gene="ribD"
                     /locus_tag="VW749_000147"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0174259.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(8498..8612)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8769..9362
                     /gene="ruvA"
                     /locus_tag="VW749_000148"
     CDS             8769..9362
                     /gene="ruvA"
                     /locus_tag="VW749_000148"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0174260.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            9372..9935
                     /locus_tag="VW749_000149"
     CDS             9372..9935
                     /locus_tag="VW749_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0174261.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            9932..10609
                     /locus_tag="VW749_000150"
     CDS             9932..10609
                     /locus_tag="VW749_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0174262.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIATYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVDYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(10764..11795)
                     /locus_tag="VW749_000151"
     CDS             complement(10764..11795)
                     /locus_tag="VW749_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0174263.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(12050..12733)
                     /locus_tag="VW749_000152"
     CDS             complement(12050..12733)
                     /locus_tag="VW749_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0174264.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(12745..13689)
                     /locus_tag="VW749_000153"
     CDS             complement(12745..13689)
                     /locus_tag="VW749_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0174265.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            13821..16652
                     /gene="uvrA"
                     /locus_tag="VW749_000154"
     CDS             13821..16652
                     /gene="uvrA"
                     /locus_tag="VW749_000154"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0174266.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            16645..17706
                     /locus_tag="VW749_000155"
     CDS             16645..17706
                     /locus_tag="VW749_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0174267.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            17838..18236
                     /gene="spx"
                     /locus_tag="VW749_000156"
     CDS             17838..18236
                     /gene="spx"
                     /locus_tag="VW749_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0174268.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            18302..18871
                     /locus_tag="VW749_000157"
     CDS             18302..18871
                     /locus_tag="VW749_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0174269.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            18958..19224
                     /locus_tag="VW749_000158"
     CDS             18958..19224
                     /locus_tag="VW749_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0174270.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            19228..19647
                     /gene="ruvX"
                     /locus_tag="VW749_000159"
     CDS             19228..19647
                     /gene="ruvX"
                     /locus_tag="VW749_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0174271.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            19663..19968
                     /locus_tag="VW749_000160"
     CDS             19663..19968
                     /locus_tag="VW749_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0174272.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            20381..21631
                     /locus_tag="VW749_000161"
     CDS             20381..21631
                     /locus_tag="VW749_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0174273.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            21628..22185
                     /locus_tag="VW749_000162"
     CDS             21628..22185
                     /locus_tag="VW749_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0174274.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            22331..23863
                     /gene="cls"
                     /locus_tag="VW749_000163"
     CDS             22331..23863
                     /gene="cls"
                     /locus_tag="VW749_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0174275.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            23941..24084
                     /locus_tag="VW749_000164"
     CDS             23941..24084
                     /locus_tag="VW749_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174276.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            24121..25659
                     /locus_tag="VW749_000165"
     CDS             24121..25659
                     /locus_tag="VW749_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0174277.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            25779..27986
                     /gene="nrdD"
                     /locus_tag="VW749_000166"
     CDS             25779..27986
                     /gene="nrdD"
                     /locus_tag="VW749_000166"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0174278.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            27998..28138
                     /locus_tag="VW749_000167"
     CDS             27998..28138
                     /locus_tag="VW749_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174279.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            28182..28688
                     /locus_tag="VW749_000168"
     CDS             28182..28688
                     /locus_tag="VW749_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174280.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            28681..29271
                     /gene="nrdG"
                     /locus_tag="VW749_000169"
     CDS             28681..29271
                     /gene="nrdG"
                     /locus_tag="VW749_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0174281.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            29268..29885
                     /locus_tag="VW749_000170"
     CDS             29268..29885
                     /locus_tag="VW749_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0174282.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            30151..30459
                     /gene="rpsJ"
                     /locus_tag="VW749_000171"
     CDS             30151..30459
                     /gene="rpsJ"
                     /locus_tag="VW749_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0174283.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            30676..31302
                     /gene="rplC"
                     /locus_tag="VW749_000172"
     CDS             30676..31302
                     /gene="rplC"
                     /locus_tag="VW749_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0174284.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            31327..31950
                     /gene="rplD"
                     /locus_tag="VW749_000173"
     CDS             31327..31950
                     /gene="rplD"
                     /locus_tag="VW749_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0174285.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            31950..32246
                     /locus_tag="VW749_000174"
     CDS             31950..32246
                     /locus_tag="VW749_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0174286.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            32264..33097
                     /gene="rplB"
                     /locus_tag="VW749_000175"
     CDS             32264..33097
                     /gene="rplB"
                     /locus_tag="VW749_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0174287.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            33201..33482
                     /gene="rpsS"
                     /locus_tag="VW749_000176"
     CDS             33201..33482
                     /gene="rpsS"
                     /locus_tag="VW749_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0174288.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            33494..33838
                     /gene="rplV"
                     /locus_tag="VW749_000177"
     CDS             33494..33838
                     /gene="rplV"
                     /locus_tag="VW749_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0174289.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            33851..34504
                     /gene="rpsC"
                     /locus_tag="VW749_000178"
     CDS             33851..34504
                     /gene="rpsC"
                     /locus_tag="VW749_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0174290.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            34508..34921
                     /gene="rplP"
                     /locus_tag="VW749_000179"
     CDS             34508..34921
                     /gene="rplP"
                     /locus_tag="VW749_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0174291.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            34931..35137
                     /locus_tag="VW749_000180"
     CDS             34931..35137
                     /locus_tag="VW749_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0174292.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            35162..35422
                     /gene="rpsQ"
                     /locus_tag="VW749_000181"
     CDS             35162..35422
                     /gene="rpsQ"
                     /locus_tag="VW749_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0174293.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            35448..35816
                     /gene="rplN"
                     /locus_tag="VW749_000182"
     CDS             35448..35816
                     /gene="rplN"
                     /locus_tag="VW749_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0174294.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            35894..36199
                     /gene="rplX"
                     /locus_tag="VW749_000183"
     CDS             35894..36199
                     /gene="rplX"
                     /locus_tag="VW749_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0174295.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            36223..36765
                     /gene="rplE"
                     /locus_tag="VW749_000184"
     CDS             36223..36765
                     /gene="rplE"
                     /locus_tag="VW749_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0174296.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            36783..37052
                     /gene="rpsN"
                     /locus_tag="VW749_000185"
     CDS             36783..37052
                     /gene="rpsN"
                     /locus_tag="VW749_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0174297.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            37337..37735
                     /gene="rpsH"
                     /locus_tag="VW749_000186"
     CDS             37337..37735
                     /gene="rpsH"
                     /locus_tag="VW749_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0174298.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            37927..38463
                     /gene="rplF"
                     /locus_tag="VW749_000187"
     CDS             37927..38463
                     /gene="rplF"
                     /locus_tag="VW749_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0174299.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            38547..38903
                     /gene="rplR"
                     /locus_tag="VW749_000188"
     CDS             38547..38903
                     /gene="rplR"
                     /locus_tag="VW749_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0174300.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            38921..39415
                     /gene="rpsE"
                     /locus_tag="VW749_000189"
     CDS             38921..39415
                     /gene="rpsE"
                     /locus_tag="VW749_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0174301.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            39387..39611
                     /gene="rpmD"
                     /locus_tag="VW749_000190"
     CDS             39387..39611
                     /gene="rpmD"
                     /locus_tag="VW749_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0174302.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            39756..40196
                     /gene="rplO"
                     /locus_tag="VW749_000191"
     CDS             39756..40196
                     /gene="rplO"
                     /locus_tag="VW749_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0174303.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            40209..41519
                     /gene="secY"
                     /locus_tag="VW749_000192"
     CDS             40209..41519
                     /gene="secY"
                     /locus_tag="VW749_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0174304.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            41670..42308
                     /locus_tag="VW749_000193"
     CDS             41670..42308
                     /locus_tag="VW749_000193"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0174305.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            42425..42643
                     /gene="infA"
                     /locus_tag="VW749_000194"
     CDS             42425..42643
                     /gene="infA"
                     /locus_tag="VW749_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0174306.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            42668..42784
                     /gene="rpmJ"
                     /locus_tag="VW749_000195"
     CDS             42668..42784
                     /gene="rpmJ"
                     /locus_tag="VW749_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0174307.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            42802..43167
                     /gene="rpsM"
                     /locus_tag="VW749_000196"
     CDS             42802..43167
                     /gene="rpsM"
                     /locus_tag="VW749_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0174308.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            43185..43568
                     /gene="rpsK"
                     /locus_tag="VW749_000197"
     CDS             43185..43568
                     /gene="rpsK"
                     /locus_tag="VW749_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0174309.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43611..44546
                     /locus_tag="VW749_000198"
     CDS             43611..44546
                     /locus_tag="VW749_000198"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0174310.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            44558..44944
                     /gene="rplQ"
                     /locus_tag="VW749_000199"
     CDS             44558..44944
                     /gene="rplQ"
                     /locus_tag="VW749_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0174311.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            45209..45475
                     /locus_tag="VW749_000200"
     CDS             45209..45475
                     /locus_tag="VW749_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0174312.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            45485..46822
                     /locus_tag="VW749_000201"
     CDS             45485..46822
                     /locus_tag="VW749_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0174313.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            47066..47758
                     /locus_tag="VW749_000202"
     CDS             47066..47758
                     /locus_tag="VW749_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0174314.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(47861..49506)
                     /locus_tag="VW749_000203"
                     /pseudo
     CDS             complement(47861..49506)
                     /locus_tag="VW749_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(49496..50587)
                     /locus_tag="VW749_000204"
                     /pseudo
     CDS             complement(49496..50587)
                     /locus_tag="VW749_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(50600..51721)
                     /locus_tag="VW749_000205"
                     /pseudo
     CDS             complement(50600..51721)
                     /locus_tag="VW749_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(51938..52135)
                     /locus_tag="VW749_000206"
     CDS             complement(51938..52135)
                     /locus_tag="VW749_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0174315.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(52210..52986)
                     /locus_tag="VW749_000207"
     CDS             complement(52210..52986)
                     /locus_tag="VW749_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0174316.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            53108..53854
                     /locus_tag="VW749_000208"
     CDS             53108..53854
                     /locus_tag="VW749_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0174317.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            53867..54847
                     /locus_tag="VW749_000209"
     CDS             53867..54847
                     /locus_tag="VW749_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0174318.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            55042..55362
                     /locus_tag="VW749_000210"
     CDS             55042..55362
                     /locus_tag="VW749_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0174319.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            55408..55716
                     /locus_tag="VW749_000211"
     CDS             55408..55716
                     /locus_tag="VW749_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0174320.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            55733..57031
                     /locus_tag="VW749_000212"
     CDS             55733..57031
                     /locus_tag="VW749_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0174321.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            57182..59620
                     /locus_tag="VW749_000213"
     CDS             57182..59620
                     /locus_tag="VW749_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0174322.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            59639..60310
                     /locus_tag="VW749_000214"
     CDS             59639..60310
                     /locus_tag="VW749_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0174323.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKRREGSINFFER
                     IKDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKAL
                     KKEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQN
                     SPSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQ
                     NSRSI"
     gene            60328..61416
                     /locus_tag="VW749_000215"
     CDS             60328..61416
                     /locus_tag="VW749_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0174324.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            61898..64399
                     /locus_tag="VW749_000216"
     CDS             61898..64399
                     /locus_tag="VW749_000216"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0174325.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            64593..65288
                     /locus_tag="VW749_000217"
     CDS             64593..65288
                     /locus_tag="VW749_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174326.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            65300..65716
                     /locus_tag="VW749_000218"
     CDS             65300..65716
                     /locus_tag="VW749_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174327.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(66531..66623)
                     /locus_tag="VW749_000219"
     CDS             complement(66531..66623)
                     /locus_tag="VW749_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0174328.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            66784..67755
                     /gene="ruvB"
                     /locus_tag="VW749_000220"
     CDS             66784..67755
                     /gene="ruvB"
                     /locus_tag="VW749_000220"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0174329.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            67736..68308
                     /locus_tag="VW749_000221"
     CDS             67736..68308
                     /locus_tag="VW749_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0174330.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            68539..69297
                     /locus_tag="VW749_000222"
     CDS             68539..69297
                     /locus_tag="VW749_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0174331.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            69306..70109
                     /locus_tag="VW749_000223"
     CDS             69306..70109
                     /locus_tag="VW749_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0174332.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            70131..71390
                     /gene="rseP"
                     /locus_tag="VW749_000224"
     CDS             70131..71390
                     /gene="rseP"
                     /locus_tag="VW749_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0174333.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            71403..73256
                     /locus_tag="VW749_000225"
     CDS             71403..73256
                     /locus_tag="VW749_000225"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0174334.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            73355..74734
                     /gene="bglA"
                     /locus_tag="VW749_000226"
     CDS             73355..74734
                     /gene="bglA"
                     /locus_tag="VW749_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0174335.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEHYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            74927..76735
                     /gene="glmS"
                     /locus_tag="VW749_000227"
     CDS             74927..76735
                     /gene="glmS"
                     /locus_tag="VW749_000227"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0174336.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGFDVDKPRNLAKSVTVE"
     gene            complement(76873..76950)
                     /locus_tag="VW749_000228"
                     /pseudo
     CDS             complement(76873..76950)
                     /locus_tag="VW749_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            77007..78056
                     /locus_tag="VW749_000229"
     CDS             77007..78056
                     /locus_tag="VW749_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0174337.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLALLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(78156..81992)
                     /gene="spuA"
                     /locus_tag="VW749_000230"
     CDS             complement(78156..81992)
                     /gene="spuA"
                     /locus_tag="VW749_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0174338.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNKSDISSLGNANASLEKTEEKPATEPT
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQ
                     AEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISL
                     LALLGLGFLLKNKKEN"
     gene            82409..82822
                     /gene="rpsL"
                     /locus_tag="VW749_000231"
     CDS             82409..82822
                     /gene="rpsL"
                     /locus_tag="VW749_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0174339.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            82842..83312
                     /gene="rpsG"
                     /locus_tag="VW749_000232"
     CDS             82842..83312
                     /gene="rpsG"
                     /locus_tag="VW749_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0174340.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            83737..85818
                     /gene="fusA"
                     /locus_tag="VW749_000233"
     CDS             83737..85818
                     /gene="fusA"
                     /locus_tag="VW749_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0174341.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            85922..90313
                     /locus_tag="VW749_000234"
     CDS             85922..90313
                     /locus_tag="VW749_000234"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0174342.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREVFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            90415..90678
                     /locus_tag="VW749_000235"
     CDS             90415..90678
                     /locus_tag="VW749_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0174343.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            90671..90949
                     /locus_tag="VW749_000236"
     CDS             90671..90949
                     /locus_tag="VW749_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0174344.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            90970..91122
                     /locus_tag="VW749_000237"
     CDS             90970..91122
                     /locus_tag="VW749_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174345.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            91144..92385
                     /locus_tag="VW749_000238"
     CDS             91144..92385
                     /locus_tag="VW749_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0174346.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            92395..92625
                     /locus_tag="VW749_000239"
     CDS             92395..92625
                     /locus_tag="VW749_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0174347.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            92848..93570
                     /locus_tag="VW749_000240"
     CDS             92848..93570
                     /locus_tag="VW749_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0174348.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            93787..95121
                     /gene="pepC"
                     /locus_tag="VW749_000241"
     CDS             93787..95121
                     /gene="pepC"
                     /locus_tag="VW749_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0174349.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(95177..96088)
                     /locus_tag="VW749_000242"
     CDS             complement(95177..96088)
                     /locus_tag="VW749_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0174350.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(96112..96915)
                     /locus_tag="VW749_000243"
     CDS             complement(96112..96915)
                     /locus_tag="VW749_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0174351.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(96943..97932)
                     /gene="manX"
                     /locus_tag="VW749_000244"
     CDS             complement(96943..97932)
                     /gene="manX"
                     /locus_tag="VW749_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0174352.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT        29303 a        17973 c        21712 g        29017 t
ORIGIN      
        1 tagaattgac aaatggggga ataatagaag tgtttattcc taatcatttg agaaagttga
       61 aaaattttat tgaagaggaa ttcaataaat ttagaaattc tcacggagct aatctaagcc
      121 tctatgaata ctgtttgctt gataattctt taactttaaa aaatgattgg aactattctg
      181 atttagttat gaaatttacg agtaattttt atgctgatat aaaagacttg ttcatggaaa
      241 attctgatat tgaaatcatc catgaagagg gagtaccttt tgtattttta gatttaatag
      301 gtgaaggtaa aaaagaatat gaaatgtttt ttcaatggtt aaacttcttt tacaaacagc
      361 ttggaatcac attgtatgct agaaatagtt ttgggtttcg gaatctaaca gtagagtatt
      421 ttggaattat tgggacagaa agatatatat ttaagatttg tccaggtgtt tataaagggt
      481 taagttatta tttgatgaaa tttttattaa aatctttttc aaatgaatat ttaaaaacta
      541 ctgatgaggt taatagatga aaaatttgat aaagttgcta ataattagat tgattgttaa
      601 cttagcagac agtgtatttt atatagtagc attgtggcac gttagcaata attattcttc
      661 gagcatgttc ttaggaatat ttattgcagt aaattatcta ccggatttgt tactaatctt
      721 ttttggacca gttattgaca gagtaaatcc gcaaaaaatt cttataatat caattttggt
      781 tcaattagca gtggctgtaa tatttttatt attattaaac caaatatcat tttgggtgat
      841 aatgagtcta gtgtttattt cagtaatggc tagctccata agttacgtga tagaagatgt
      901 gttgattcct caagtggtag aatatgataa gattgtattt gcaaattctc tttttagtat
      961 ttcgtataaa gtattagatt ctatttttaa ttcattcgca tcatttttac aggtggcagt
     1021 aggatttatt ttattggtta agatagatat aggcatattt ttacttgctc tatttatatt
     1081 gttgttgtta aaatttagaa ctagcaatgc gaatatagaa aacttctctt tcaaatatta
     1141 caagagagaa gtgttgcaag gtacaaagtt tattttaaat aataaattat tatttaaaac
     1201 cagtatttct ttaacgctta taaacttttt ttattcattt cagacagtag ttgtaccgat
     1261 tttttctatt cgatattttg atggtccgat tttttatggt atttttttaa ctattgctgg
     1321 tttgggtggt atattgggaa atatgctagc gccaatcgta ataaaatatt taaaatcgaa
     1381 tcaaattgtt ggtgtatttc tttttttgaa cggctcaagt tggttagtag caattgttat
     1441 aaaagactat actttatcac ttattttatt tttcgtttgt tttatgtcta aaggagtctt
     1501 caatattatt tttaattcgt tgtaccaaca aatacctcca catcaacttc ttggtagggt
     1561 aaatactacc attgattcta ttatttcttt tggaatgcca attggtagtt tagttgcagg
     1621 aacgcttatt gatttgaata ttgaattagt gttaattgct attagcatac cttatttttt
     1681 gttttcttat attttttata cggataatgg attgaaagaa tttagtatat attagaaatg
     1741 tttatgttca ttcaaaagca taatgactat aactgaaaaa gaaaagtgat atctttaagg
     1801 ttgttcttct tggtggtgag attcgtgaga caacccaagc ttttgtcgga aagattacca
     1861 atgctttgat ggataggatg tactttagca agatgttttt agtggtaacg gtatcgtgga
     1921 tggacgtgta ataacctctt ctttcgagga gtattttact aaaaaactag ccttggagcg
     1981 ttccccagaa acggacttac tcattgactc ttcaaagatt tggggagaag attttgcttc
     2041 atctgttcct tgaaaaaagt cacagcagtc atcacagacg atagtactga acaaaactat
     2101 gaagagttag aaatttatac gcaggtgatt gtataaagga tctggaaata gataagaagt
     2161 tgattagtat tgacctaggt ggtacaaata ttaagattac tgttctttca aatgacggtg
     2221 agattgaaac tttgtggagt attacaacag atacaagtga gaaaggttct caaattatat
     2281 cggacatcat cagttctatt aaaaataaat tgaccgaacg gaatattcct gatagcgacc
     2341 ttcttggaat cggtatggga agttgctcat catactttcc ttgtaaatca taggggctat
     2401 aaactctccg tctacttgtc ctgcaacaat tgaagtctgc tcaaaacgcc gtccgctaat
     2461 cttttcatag actttctccc ttttaggagc ctagctttct agtttgttct ttgattttta
     2521 ttgagtatac cactatttta ctccctctgg caagggactt tgtctatgtg gagggattgg
     2581 gctcctatgt ggtggagctt ttctgttctt tctgaaatat ggtataatag cactaatcaa
     2641 tttctaggaa aatagataca gaaaggggct gaaagatgtc tcatattatt gaattgccag
     2701 agatgctggc aaaccaaatc gcggctggag aggtcattga acgtcctgcc agtgtggtca
     2761 aagagttggt agaaaatgcc attgacgcgg gctctagtca gattatcatt gagattgagg
     2821 aagctggtct caagaaggtt caaatcacgg ataacggtca tggaattgcc cacgatgagg
     2881 tggagttggc cctgcgtcgc catgcgacca gtaagataaa aaatcaagca gatctctttc
     2941 ggattcggac gcttggtttt cgtggtgaag ccttgccttc tattgcgtct gttagtgtct
     3001 tgactctgtt aacggcggtg gatggtgcta gtcatggaac caagttagtc gcgcgtgggg
     3061 gtgaagttga ggaagtcatc ccagcgacta gtcctgtggg aaccaaggtt tgtgtggagg
     3121 atctcttttt caacacgcct gcccgtctca agtatatgaa gagccagcaa gcggagttgt
     3181 ctcatatcat tgatattgtc aaccgtctgg gcttggccca tcctgagatt tcttttagct
     3241 tgattagtga tggcaaggaa atgacgcgga cagcagggac tggtcaactg cgccaagcaa
     3301 tcgcaggaat ttacggtttg gtcagtgcca agaagatgat tgaaattgag aactctgacc
     3361 tagatttcga aatttcaggt tttgtgtcct tgcctgagtt gactcgggct aaccgcaatt
     3421 atatcagcct cttcatcaat ggccgttata ttaagaactt cctgctcaat cgtgctattt
     3481 tggatggttt tggaagcaag cttatggttg gacgttttcc actggctgtc attcacatcc
     3541 atatcgaccc ttatctagcg gatgtcaatg tgcatccaac taagcaagag gtgcggattt
     3601 ccaaggaaaa agaactgatg actctggttt cagaagctat tgcaaatagt ctcaaggaac
     3661 aaaccttgat tccagatgcc ttggaaaatc ttgccaaatc gaccgtgcgc aatcgtgaga
     3721 aggtggagca aactattctc ccactcaaag aaaatacgct ctactatgag aaaactgagc
     3781 cgtcaagacc tagtcaaact gaagtagctg attatcaggt agaattgact gatgaagggc
     3841 aggatttgac cctgtttgcc aaggaaacct tggaccgatt gaccaagcca gcaaaactgc
     3901 attttgcaga gagaaagcct gctaactacg accagctaga ccatccagag ttagatcttg
     3961 ctagcatcga taaggcttat gacaaactgg agcgagaaga agcatccagc ttcccagagt
     4021 tggagttttt cggacaaatg cacgggactt atctctttgc ccaagggcga gatggacttt
     4081 acatcataga tcagcacgct gctcaggaac gggtcaagta cgaggagtac cgtgaaagca
     4141 ttggcaatgt tgaccagagc cagcagcaac tcctagtgcc ctatatcttt gaatttcctg
     4201 cggatgatgc cctgcgtctc aaggaaagaa tgcctctctt agaggaagtg ggcgtctttc
     4261 tagcagagta cggagaaaat caatttattc tacgtgaaca tcctatttgg atggcagaag
     4321 aagagattga atcaggcatc tatgagatgt gcgacatgct ccttttgacc aaggaagttt
     4381 ctatcaagaa ataccgagca gagctggcta tcatgatgtc ttgcaagcga tctatcaagg
     4441 ccaatcatcg tattgatgat cattcagcta gacaactcct ctatcagctt tctcaatgtg
     4501 acaatcccta taactgtcct cacggacgtc ctgttttggt gcattttacc aagtcggata
     4561 tggaaaagat gttccgacgt attcaggaaa atcacaccag tctccgtgag ttggggaaat
     4621 attaaaagta taaaaaagtc tgggaaaaat tttcaaaatc agaaaaacgc ataaaatcag
     4681 gtgttcaaaa accttgattt tatgcgtttt atcatagaaa tatttacttc attttttcct
     4741 aattcttttc gaaactcttt ttaaacgacg tcagttttat cagtaatctc aaaacagtgt
     4801 tttgagctaa ttttgccagt tttgtctgta acatcgaagt tgtgttttac cactctgcga
     4861 ctggtttcct agtttgctct atgattttca cagagtatta aattgcgatt ttgccaagtt
     4921 tctttattcg tctaaaagta gagtctgttc tatgcgtcta atgtacgaat taggttgacc
     4981 atttcaatag ctccttgtgc acactcagaa cccttatttc ctgctttagt gccagctcgt
     5041 tctatggctt gttcaattgt atctgtcgtt agcacaccaa acataacagg aatttcgcta
     5101 tttaaactga tttgggcgat tcccttagat acctcgctac atacataatc ataatgactt
     5161 gtattccctc taatgacagc tcccaagcag ataattgcat catatttttt actttttgcc
     5221 atttttgatg caatcagtgg tatttcaaaa gctcctggaa tccaggctac cgctatatct
     5281 ttctcgttta cattctctct tttgagatta tctagtgctc cagataataa ttttgaagtt
     5341 ataaattcat taaatctcgc tacaacaata cctattttaa tattgtttgc tactaaatta
     5401 ccttcataag tgttcattta tttttcctcc atatttaaaa tgtgacccat tcgatttttc
     5461 tttgtttcta aataaaaact atcgtaagga ttggcttcta tttcgattga tattctactg
     5521 gaaatggtaa ttccatattt ttctaactgt tcaaccttgt caggattatt tgtcagtaaa
     5581 tgaagtgact gaagtcccag atctttaagc atttgtgctc caatatgata ttctcttaaa
     5641 tcaccttcaa agcctaatgc aagattggca tcaagcgtat ccatgccttg atcttgtaaa
     5701 tgataggctt ttaatttatt gataagtcca attcctcgtc cctcctgtcg caagtaaagt
     5761 aagacacccg aaccattctc aacaatcatt ttcatagctt tatcgaattg ctgtccacaa
     5821 tcgcaacgta aagagcctaa aacatcccct gttaaacatt cggagtggac ccgacataat
     5881 acattggctt catcctctat gtttcccata ataagagcaa gatgatgttc cccatttagt
     5941 ttatctatat agctaattgc tttgaaatta ccgtatctag taggcatatt gacagttgaa
     6001 actcgttcta ccagctgatc atatactttt ctatattctt gtaattcttt gatggtaatt
     6061 agtggaatgt tgtgtttctt cgagaactga attaaatcat ctgttctcat cattttgcca
     6121 tcatgattca ttatttcaca acataggcca cactctttta gtccagctaa ttttaataaa
     6181 tcaacagttg cttctgtgtg tccatttctt tctagaacac cacctttttt tgcaattaaa
     6241 ggaaacatgt gtcctggcct gcgaaaatca gagggtgtta tatcttcagc tacacacata
     6301 cgtgcggtca gtcctctttc ctcggcagaa atacctgtgg tcgtttcttt ataatcaatt
     6361 gaaactgtaa aagcagtctt atgattatct gtattgtttt caaccatagg tgaaagcatt
     6421 aattgattag ctaaactttc gctcataggc atacaaatta atcctttggc ataagtagcc
     6481 ataaaattaa cattttctgt tgtagctgct tgtgcagaac aaattaagtc tccttcattt
     6541 tctctatcct tgtcgtctat aacaagaaca agtcgtccct tctgcaatgc ttctaatgct
     6601 tcttgtattt ttcgatattc cattgactga ttatcctttc tgctaaaatc cattttgata
     6661 taatagttcc ttagatattt ctgattttgg agagttatcc atcagttttt gcacatattt
     6721 acctaagata tcattttcaa gatttactgt actcccgact tgtttactct taagaatggt
     6781 ttgttccaag gtatgaggga taacagatac tgaaaagttt actttggaga ctttagcgac
     6841 agtcagacta atgccgtcaa ttgtaataga tcctttttca actattaaat ctaaaatttc
     6901 tttttgtgtg ttgatttgat accatacagc attatcatct ttttttattg acgagatttt
     6961 tcctgtacca tcaatgtgtc ctgtaacgac gtgaccccca agtcgaccgt tgacagataa
     7021 ggctctttct agattcacct cacttccatg ttttaataga gtaagagctg ttcgactcca
     7081 tgtttcattc attacatcaa ctgtaaagga ttgatggttg aaatgagtaa ctgtaagaca
     7141 gataccattt actgctatac tatcgcctaa atggatatcc gttaatattt ttgaggcttt
     7201 aattgatagt ttacaattac gagagtcttt ctgtattctt tcaacttttc cgatttcttc
     7261 aattattcct gtgaacatgg ataaatcact tcactttcta tgagatagtc atttcctatt
     7321 tgagaaaaag cataaggttt caatctaata gcgtcatttg gcaaagaaat gccttcacct
     7381 ccgacaggaa acttggcact gcctccaaaa atttttggtg caatatatat tttcagctca
     7441 tcaacaattt gttgttccaa agcactccaa ttcattagac tgcccccttc tagaactagg
     7501 ctatcaatct gcatgtttcc tagatgttgc attaaactcg ataagtctat atgattgcct
     7561 tttttcttta tggaaagtat ttcacagcca tgattttgat atagcttcat tttatttttg
     7621 tcttcagagg aagtggcaat gtaagtttta atatcatttg ctgtttttac gattttagag
     7681 gtaagaggag ttcgtaaatg tgtatcgcat atgatacgga taggattttt cccttcctcc
     7741 aatctacatg tcagcaaagg atcgtcttga ataacagtat tgactcccac cataattgca
     7801 ctaacatagt gtcgtaactg atgcacatgc tttcttgctt cttcttcagt aatccatttg
     7861 gattgatttg ttttagtggc tatttttcca tccattgaca ttgcatattt cataaaaaca
     7921 tagggtacat gctgggtaat atactttcta aaacttttta ttaagttaag acactcattt
     7981 tctaaaattc caacagtaac ttgaagatta ttttcctcaa gtatctttac tccttttcca
     8041 gatacaatag gattacagtc taggcttcca atgactactc ttgtaatacc actatcgatt
     8101 atagcatcta tacagggagg tgttttcccg aagtgacaac agggttcaag tgttacataa
     8161 agcgtcgctc cgacagggga ttctctacag tttttaagag catttctctc agcatgtggg
     8221 ccaccaaaaa actcatgata accttgtccg atgatgtgat tatcttttac aataactgcg
     8281 ccgaccatag gattgggatt gacgtaacca gccccttttt gtgccagttt tattgctaat
     8341 ttcatatatt ttgaatcgct catctcacta cctccaaaaa aaatatacct tgaatagggg
     8401 actactcaag gcatacaaaa gaaaacttat gcgattaaca aaaatactct gaaatgacaa
     8461 gtaatcattt cagagcacgc aaaaagcaca aatatacttt tatcttcttt catccagact
     8521 atactgtcgg ctttggaatt tcaccaaatc atgcctttcg gctcgtgggc tataccaccg
     8581 gtagggaatt acaccctgcc ctgaagatag ttattcaatt acagatgatt atagtactta
     8641 attttgaata tgtcaacaga taaataccga ttgtttttga tatactgtat ttgtgataat
     8701 cgattctcgc tcctcggata aagaaaatat gatatactag ataaacgaaa taagagagaa
     8761 ggaatactat gtacgcatat ttaaaaggaa tcattaccaa aattactgcc aaatacattg
     8821 ttcttgaaac caatggtatt ggttatatcc tgcatgtggc caatccttat gcctattcag
     8881 gtcaggttaa tcaggaggct cagatttatg tgcatcaggt tgtgcgtgag gacgcccatt
     8941 tgctttatgg atttcgctca gaggatgaga aaaagctctt tcttagtctg atttcggtct
     9001 ctgggattgg tcctgtatca gctcttgcta ttatcgctgc tgatgacaat gctggcttgg
     9061 ttcaagccat tgaaaccaag aacatcacct acttgaccaa gttccctaaa attggcaaga
     9121 aaacagccca gcagatggtg ctggacttgg aaggcaaggt agtagttgca ggagatggcc
     9181 ttcctgccaa ggtcgcagtg caagcaagtg ctgaaaacca agaattggaa gaagctatgg
     9241 aagccatgtt ggctctgggc tacaaggcaa cagagctcaa gaaaatcaag aaattctttg
     9301 aaggaacgac agatacagct gagaactata tcaagtcggc ccttaaaatg ttggtcaaat
     9361 aggagcagag aatgacaaaa cgttgttcgt gggtcaagat gaccaacccg ctctacatcg
     9421 cctatcatga tgaggagtgg ggtcagcccc tccatgatga ccaagcattg tttgagttgt
     9481 tgtgtatgga aacctatcag gcaggcctgt cttgggaaac ggtactcaac aaacgccaag
     9541 ctttccgaga agcctttcat agctatcaaa ttcactcagt cgcagagatg actgacactg
     9601 aattggaagc catgctggag aatccagcta tcattcgaaa tagagccaag atttttgcta
     9661 cacgcgctaa cgcccaagcc tttctacagt tacaggcaga gtacggctct tttgatgcct
     9721 atctttggtc ttttgttgag gggaaaactg tcgttaacga tgttcctgat tatcgccaag
     9781 ccccagctaa aacaccctta tctgagaaat tagccaaaga tctcaaaaaa cgaggcttca
     9841 agttcacagg cccagtcgcc gtattgtctt ttctacaggc tgcagggcta gttgatgacc
     9901 acgagaatga ttgtgagtgg aaaggtctta aatgatgtct aacaaaaata agggaattct
     9961 gatttttgcg attctctata cagtcctctt tgtgtttgat ggcgttaaat tgctggcttc
    10021 tttaatgcca tctgccattg caacttatct tgtttatgta gttttagctt tatatggctc
    10081 cttcttgttc aaggatagat tgatccaaca atggaaggag attagaaaga ctaaaagaaa
    10141 attcttcttt ggagtcttaa caggatggct ctttctcatt ctgatgactg ttgtctttga
    10201 atttgtatca gagatgttga agcagtttgt gggactagat ggacaaggtc taaatcagtc
    10261 taatattcaa agtacctttc aagaacaacc actactgata gctgtttttg cttgtgtcat
    10321 tggacctctg gtagaagaat tatttttccg tcaggtctta ttgcattact tgcaggaacg
    10381 gttgccaggt ttactaagca ttattctggt aggacttgtt tttgctctga ctcatatgca
    10441 cagtttggct ctatcagagt ggattggtgc agttgattac ttaggtggag gccttgcctt
    10501 ttctattatt tatgtgaaag aaaaagagaa tatctactat cccctacttg ttcacatgtt
    10561 aagcaacagc ctctccttaa tcattttagc tatcagtata gtaaaatgaa ataagaacag
    10621 gacaaatcaa tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac
    10681 tattctagtt tcaatacact gtaacatgtg atgaaaatgc cagtaatgat accgagaaaa
    10741 aagctgagaa acttttccca gctttatttg ttatagtcaa agcgaatgac ttgttcctgt
    10801 gcatctacat gagcatggac cccaaagggt acaattgctc ttggagttgc gtggccgaca
    10861 ttcagattat agacaatcgg gatattgttg tcaatgatat ccaatagtgc ctctttatag
    10921 tcgtcatgga aagtttcatc cataggtttt ccgaccaaga gtccattgat gaccgcgaat
    10981 atgccagtgt cctttaaagt tagcaacatc tttttgaagt cttctggctt aggctcttct
    11041 tcgcttgttt cgagcaagag gattttccct tcccagtctg acaagtcagg gaaaagtttg
    11101 tatttttggc agagttccgt gctatctgcg tatcgagagt tgtcaaagat atcgtagagg
    11161 gattcgaggc aaccaccgag gattttcccc tcgaactgag cacttccttg caacaagtca
    11221 aaacctgtat ttgtatgact gacacgaggt gttcccaggg ccgtgggact aaaatcagtt
    11281 cgttcctcat accaaacgtc actagggcgg atttctgaaa ttcttcccgt ctcaatcaat
    11341 tctttaaagt agtgaaggct ataggctagc atttctttgt ctaattcaca aatgtctgct
    11401 aaaaaggatt gaccataaaa agtcttgatt cctaatttat gcaacatgag gtggttcatg
    11461 gttgtatccg agaagccaag aaaaattttt tgtttgataa ccttttggag ttggtcattt
    11521 tcaaaaagat aaggtagcaa gcgataggta tcgtctccac ctatggcaca taggatcatg
    11581 tcgatgctat catcagaaaa ggcatgaatc aaatcctctg cacgagcttc aggatggtcc
    11641 ttgataaagt ctaatccttt taacgaatgg ggcaaaaaga tgggattgag tcccagaacc
    11701 ttgagacgtt ggatacccaa gtccacttcg tgtttgacaa aatcctctcc gataatgcca
    11761 ctagataaac taacaatacc aatagtagaa accatatctc atcctcctag aaatagattg
    11821 agcctatttt atcacaaaat ataagagaaa gctatgtggg atttcagaag aatactttta
    11881 atactcttcg aaaatctctt caaaccacgt cagttttatc tgcaacctca aagctgtgct
    11941 ttgagcaacc tgcagctagc ttcctagttt gctctttgat tttcattgag tataactcaa
    12001 aaaagtaagt gaaaaagcaa ccgcacctgc agttgctttt atcgttttct tattcttgat
    12061 agcgtgttgg tcctgcactt gcactacgga tattcaagcg tttcttgaga tagaagcgaa
    12121 gggctaggag agctgctcca ataatagcta gtggcaatgg atccagtact gggttaaggc
    12181 tagctggtag gaagcttgtt gcaaagaaga caagcaacca aaggaacata gaagctagga
    12241 taactagtac agatttccag aaaggtggac gttgactgcg atccatatct ggtccatagt
    12301 attggtaaac aaagtagtac atcaagtaga aggcaaatcc accaaccagt ccaactaata
    12361 gaagagtaat caatccatag ccgaaagctt gatctgccgc aaagaaggtt gtgagggcgc
    12421 tgacaagggc aaagaggcta gtgatgaaaa gagctgagtc cataatcatc agttttgggt
    12481 catcattttc ttttggatgc tctttttcgt actgctcttt gacagtgaag ctatgagccc
    12541 aatgagttgg tgcgccgtat agggaacggg cagttgtacc tttagattgc tcctcaagga
    12601 tttggggaat gacttcctca aaaatagtct ggatttcagc gtctgttttc ccatctttga
    12661 tgaattgttg ggtagcaatg tggacaaact cttggttttt cttagttaat ttttgtagat
    12721 caatttgaga cataggaact cctcttagaa ccatttttta tggatgagat agagagtgag
    12781 cgagacactc atagcaaagg cgataaagac gattaaccag aaggcatttg gctctccgtt
    12841 taggggaatt tcattatcct taaagttcat cccgtaggca gaaaagacca tggttgggat
    12901 ggacatgacg atggtcacaa gggccaaggt tttcatgatg ttgttctggt tgttagaaat
    12961 gatagaggca aaggtctctg tcatagaatg caagacgttt ccataaatat ctgccatctc
    13021 gatggcctgt tgggtttcaa tcagggtgtc ttcaagcagg tcttcgtcct caaggtattt
    13081 cttgatattg ctggttgaac tggtcaattt cttaatcacg cgctcatttg ttttgaggga
    13141 ggccttgaaa tagacgatag ttttttccaa ttccatgagc tcaatcaatt cttcattacg
    13201 agttgattga tgcagttgac tttcgatttg ttcactcttg cggtcgattg aacgaagggc
    13261 tgttaggtaa agctctgcat tgcgataaag aatttgaaag ataaaacgtg aacgcatgaa
    13321 ggtatagaaa ttacgcaatc gacggttgat aaagacatca aggacaggta gtggttccaa
    13381 acacgtagtg ataatggttt cctcagtgat gataatacca agcgggatgg ttacgtagta
    13441 ggtgcggtta tttctttcct ccgtgaccgg cacgtctacg ataatcaggg tatactcgtc
    13501 ttcaatggta atacgagaca tttcttccgc atcgagcggt gctcgaaggt cggcaatatc
    13561 aatatcgaag gtgttggcga tttcgagtga ttcattttga gtcggattga cgagattgat
    13621 ccaagtaccc ggttcaagcg tatcgatctc tttaaattca gttgttgtag agagaaaaac
    13681 ttgtttcata tcccttatcc tttctcattt ttcagatttt ttcacactgt actattatac
    13741 tacaaaatcg gccttttggg taatagaatc tcactttttt tggtataatg gtaagcaata
    13801 atggactaga aagaacaaag atgcaagata aaattgtcat tcatggggcg cgtgcccata
    13861 atttaaaaaa tattgatgtg gagattccgc gagacaagtt ggttgtcgtg actggcttgt
    13921 caggttcagg gaagtccagt ctggcttttg atactctcta tgcggaggga caacgtcgct
    13981 atgtagagag tttgtctgcc tacgctcgtc agttcttggg aaatatggaa aaaccagatg
    14041 tagatgccat tgatggtctc agcccagcta tttccatcga ccagaaaacg actagtaaaa
    14101 atcctcgctc gacggtggga acgacgactg aaatcaatga ctatctgcgt ctcctctacg
    14161 cacgtgtggg gacgccttac tgtatcaacg gacatggagc tatcaatgct tcttctgtgg
    14221 agcaaatcgt tgataaggtt ttggagttac ctgaacgcca gcgcttgcag atcttggctc
    14281 ctgtcatccg caagaaaaaa ggccaacata agagtgttat cgagaaggtt cagaaagacg
    14341 ggtatgttcg tgttcgtgtg gatggggaag tctatgatgt gaccgaagtg ccagagttgt
    14401 ctaagagcaa gcaacacaat atcgatgtcg tggttgaccg tattgttatc aaggagggca
    14461 ttcgtagccg tctctttgat tccattgaag ctgcccttcg tatcgcagaa ggttatgtga
    14521 ttatcgacac catggacgac tctgagttgt tgttctctga gcattatgcc tgtccagttt
    14581 gtggatttac tgtcccagag ttagaacctc gtctcttctc tttcaatgct ccctttggct
    14641 cttgtagtga gtgtgacggc ttggggatca agctggaggt agatactgat ttggtagtgc
    14701 cagatgccag caaaacctta cgtgagggag cgctagcacc ttggaatcct atctcatcca
    14761 actactatcc aaacatgtta gagcaggcca tgaaagtctt tggagtggct atggataagc
    14821 cttttgagga cctgtcagaa gaagataaga acttgattct ctatgggtca gatggtaagg
    14881 aattccattt ccactatgag aatgaatttg gtggcgtgcg cgatatcgac attccgtttg
    14941 agggagttat caataatatc aaacgtcgtt accatgaaac caatagcgat tacactcgca
    15001 ctcagatgcg tctctacatg aatgagctga cctgcggaac ctgtcaaggc tatcgtctca
    15061 atgaccaggc cttgtctgtc cgtgtgggcg gccagcaagg gccacatatt ggagaaatct
    15121 cagacctgtc tatcgctgac cacttggact tggtgagcca gttaactttg tctgaaaatg
    15181 aagccatcat tgctcgtccc attctcaagg aaatcaagga tcgtttgacc ttccttaata
    15241 atgtgggtct taactatcta accctgtcac gttcagcagg aaccctttca ggtggggaaa
    15301 gtcagcgcat tcgtttggca acccagattg gttccaacct atcaggcgtc ctctatatcc
    15361 tagacgagcc gtcaatcggt cttcaccaga gggacaatga ccgcctgatt gccagtctga
    15421 aaaagatgcg tgacttgggc aatactctta tcgtggtgga acacgacgaa gataccatgc
    15481 gtgaagctga ttatctgatt gacgttggtc ctggtgccgg tgtttttggt ggtgagattg
    15541 ttgcagcagg tacacctaag caagtggctc gcaacagcaa gtctatcaca ggtcagtact
    15601 tgtcaggcaa acgtgtcatc ccagtaccag aagagcgccg tgtcggaaat ggtcgtttta
    15661 ttgaagtgac aggagcgcgt gagaacaact tgcaaaatgt cacggctcgc tttccactag
    15721 gaaaatttat cgcagtgaca ggtgtgtcgg gttcagggaa atcgactcta atcaacagca
    15781 ttctcaaaaa agccattgcc cagaagctca accgtaattc agacaaacct ggtaagttta
    15841 agactattac agggattgag catgtcgacc gtttgattga tattgaccag agccctatcg
    15901 gacggacgcc gaggtctaac ccagctacct atacaggagt ttttgacgat atacgtgacc
    15961 tttttgctca gacaaatgaa gccaagattc gaggctacaa gaaggggcgc ttcagtttca
    16021 acgtcaaggg aggtcgctgt gaagcttgct caggtgacgg gattatcaag attgagatgc
    16081 acttcttgcc agatgtttat gtggcttgtg aagtttgcca cggaacccgc tataacagtg
    16141 aaaccctaga agttcactac aaggaaaaga atatttcgca ggtcttggat atgacggtca
    16201 acgatgcggt agaatttttc caacacattc cgaaaattca acgcaaactc cagaccatca
    16261 aggatgtagg gctaggctat gtgaccttgg gacagccagc taccaccctt tctgggggag
    16321 aagcccaacg tatgaagtta gctagcgaac tccacaaacg ctcgacagga aaatctttct
    16381 acattctgga tgagccgacg acagggcttc atacagagga cattgctcgc ctgctcaagg
    16441 ttttagctcg ctttgtagac gatggcaata cagtcctcgt catcgagcac aatctggatg
    16501 ttatcaagac ggcagaccat atcattgact tgggacctga gggcggtgtc ggtggtggaa
    16561 ccatcatcgt aacaggaact ccagaagaag tagctgccaa cgaagccagc tatacaggac
    16621 actatttgaa aggaaagtta catcatgaat aaacgcgtac aagcatttct agctaaaatg
    16681 caagaaaaag aactagatgg tatcatcatc aacaatctta aaaacgtcta ttatttgact
    16741 ggtttttggg gctcaaacgg aacagtcttt atcagtcgtg accgtcaggt cttagtgaca
    16801 gactctcgct atatcatcgc agctaagcaa gaaaccagtg gttttgagat tgtggctgat
    16861 cgtgatgaat tggctgtcat tgcaggaatt gttaaggaca tgggcttgac tcgtatcggt
    16921 tttgaagatg agatttcagt gtcttattac caccgtatgc aggcagcttt tgcaggtttg
    16981 gacttgtttc cgcaaactca gtttgtggaa ggtcttcgta tgattaagga tgaggcagag
    17041 attgcagcga ttcgcaaggc ttgttctatc tcagaccaag ctttccgcga tgcgcttgac
    17101 tttatcaaac caggaaaaac tgaaattgag attgccaact tccttgactt ccgcatgcgt
    17161 gagttgggag catctggctt atcttttgat acgatcctag ctagcggtat caattcttct
    17221 aaaccccatg cccatccaat gcacaaacca gtggagttgg gagaagccat taccatggac
    17281 ttcggctgtc tctatgacca ctatgtcagt gatatgaccc ggactatcta tctagggcat
    17341 gttagcgatg agcaggcaga gatttacaat acggttctaa aagctaacca agccttgatt
    17401 gaccaagcta aggcaggctt aggtttccgt gactttgaca aaatccctcg tgatattatc
    17461 attgaggcag gttatggcga ctactttact cacggcattg gccacggtat tggtctggat
    17521 atccatgagg aaccctactt tagccagact tctacagaaa ctattaagac aggtatggcc
    17581 ttgaccgatg aaccaggtat ctatatcgaa ggcaaatatg gcgttcgtat cgaggatgat
    17641 atcctgatta cagagacagg ttgtgaatta ttgaccctag ctccaaaaga gttgatagtc
    17701 atttagttgt ttgtcaagaa aaaagtacga aaatgacgaa aaaagtcaaa aaaaattaaa
    17761 aataggtcgc aagtcggatg ttttttatgg tataatagac taaactgata gtaacatgta
    17821 gcgaaagggg taggtacatg attaaaattt atacagtctc aagttgtact agctgtaaaa
    17881 aagcaaaaac ctggctcaat gcccaccagt taagttataa agaacaaaac cttggtaaag
    17941 aaggaattac gagagaagaa ttactggata ttctaaccaa aacagataac ggaatagcca
    18001 gcatcgtttc gtctaaaaat cgctatgcca aagcccttgg agtggatatt gaagatttga
    18061 gtgtcaatga agttctcaat ctgattatgg aaacaccgag aattttaaag agcccaatcc
    18121 ttgtagatga aaaacgcctg caagttggct acaaggaaga cgatattcgt gccttcctac
    18181 cacgctctgt ccgtaatgta gaaaatgcag aagcacgttt acgtgcagct ctataaacat
    18241 caaggctggg agcaattccc agtcttattc tattttaatt tcaaaaagaa agaagaaaga
    18301 aatgaaaaaa atagttcttg ttagtctagc tttccttttt gtcctggttg gttgcggaca
    18361 gaaaaaagaa actggaccag ctacaaaaac agaaaaggat acgcttcagt cggcattgcc
    18421 agttattgaa aatgccgaga agaatacagt tgtaaccaag actttggtct tgcccaagtc
    18481 agatgatggt agccagcaaa ctcaaaccat tacatacaag gacaagactt ttttgagctt
    18541 aacgattcaa caaaaacgtc cagtttctga tgagttgaag acttatattg accaacatgg
    18601 agtggaagaa actcaaaaag ctcttcttga agcggaggag aaggataagt ctatcattga
    18661 agctcgtaaa ttggtaggtt tcaaacttga aacaaaacta ttgagcgcaa cggaacttca
    18721 aacaacgact agttttgatt ttcaagttct ggatgtcaag aaggcttccc agttggaaca
    18781 tctgaagaat attggtttgg aaaatctttt gaaaaatgaa ccaagcaaat atatttcaga
    18841 cagattggca aatggtgcga cagaacagta gaaaatccaa ataaatagac tgcctgaatt
    18901 gtagaaggta aggaattatg ctataatggt actattctaa ggaaagaggg tgttagaatg
    18961 ggatttactg aagaaacagt acgttttaaa ttggacgatt ccaataaaaa agaaattagc
    19021 gaaactttga cagatgttta tgcttcgttg aacgataagg gttacaaccc aattaaccaa
    19081 atcgtaggtt acgtattgag tggagaccct gcctacgttc ctcgttataa taatgcacga
    19141 aatcaaatcc gtaagtatga gcgtgatgaa atcgttgagg aattggttcg ctactacctc
    19201 aaaggacaag gagtcgatct ataacctatg agaattatgg gattggacgt cggttcaaaa
    19261 acggtagggg tggcgattag cgatccgctt ggttttacag ctcaagggct tgaaatcatc
    19321 cagataaatg aagaacaagg ccaatttggt tttgaccgcg ttaaggaatt ggttgatact
    19381 tacaaggtgg aacgatttgt agtgggcttg cctaaaaaca tgaacaatac aagtggaccg
    19441 cgcgtagaag ctagtcaagc ctacggagca aagctagaag agttttttgg tttaccagta
    19501 gactatcagg atgaacgctt gacaacagtg gctgctgagc gcatgttgat tgaacaagca
    19561 gatatcagtc gcaataagcg caagaaagtc attgataagt tagcagctca gctgatttta
    19621 caaaattatt tagatagaaa attttaatat aaaggagagg ctatgtcaca cgatcataac
    19681 cacgaccacg aagaacgtga actaatcaca ctagtagatg agcaaggaaa tgaaaccttg
    19741 tttgaaatcc ttttgacaat tgatggaaaa gaagaatttg gtaaaaacta tgttcttcta
    19801 gtaccagtta acgcagaaga agacgaagac ggacaagttg aaatccaagc ttactcattc
    19861 atcgaaaacg aagatggaac agaaggcgaa ttgcaaccaa tcccagaaga ctcagaagac
    19921 gaatggaaca tgattgaaga agtcttcaac agctttatgg aggagtgata cagtctggga
    19981 gactgtatca gcccaactcc cagaaatggg gaagagttgg aacgtccagt ggatgttttt
    20041 agcccagttc ctttaaataa gagagaactg gtaggttcgg ggggacgttt ttagcccagc
    20101 tcctttaaat aagatagagc tggtaagtct gggagactgt atcagcccaa ctcccagaaa
    20161 tggggaagag ttggaacgtc cagtgaacat ttttacccca actcttagaa attgagaaga
    20221 gttggaacat ctagtggatg tttttagccc atattcacat tcatagtggc tagttattag
    20281 ctaaccaggt aagaggtcgg gacgaaaatc ctggccttgt ttttattagt aaccatactt
    20341 taatgcgata attgattgga cttttgtcaa ggagatgtgt atgtttgaag tagaagaatg
    20401 gctccatagt cggattggtt taaattttcg atcaggtttg ggccgaatgc agcaagcggt
    20461 ggatttgtta ggaaatcctg agcagtctta ccctattatc cacgtaacag ggactaatgg
    20521 gaaaggatct accattgctt ttatgaggga attatttatg gggcatggca aaaaagttgc
    20581 gacctttacc tcccctcata tcgtctctat caatgaccga atctgcatta atgggcaacc
    20641 tatagcagac gcagacttta tccgtttggc tgatcaggtc aaggagatgg agaaaacgct
    20701 tctgcaaact cctgaccagt tgtccttttt tgaattgctg accttggttg cttttcttta
    20761 ttttagggag caagaggtgg atttggtttt attagaagtg ggaattggtg gcttacttga
    20821 cacgaccaat gtggtaactg gagagcttgc tgtcatcacc tccattgggc ttgaccatca
    20881 agaaaccttg ggtgatagtc tagaagcaat tgcagagcag aaagctggta ttttcaaggc
    20941 tggtaagaag gcagtgattg cgaaattgcc tccagaagct aggcttgtct gtcagaaaaa
    21001 agccgaatct ttagctgtta acctttatca ggcaggtcaa gattttttaa tgctgaatgg
    21061 tgatttttca agctctttac taaatctttc acagctgaac ataggcttag aaggagtcta
    21121 tcagcaggag aatgcagcct tggcgttgca aacttttctt ctttttatgg gagaaggaaa
    21181 ggaagctgtt gatgaacagg ctgtaagaaa ggccttggaa cagacccatt gggctggtcg
    21241 cttggagcgt attcgcccac agatttactt ggatggtgct cataacctcc ctgccttgac
    21301 tcgcttggtt gagtttatca aagaaaaaga gcaggaaggc tatcgacctc aaatcctttt
    21361 tggagccttg aaacggaagg attatcaagg gatgttaggt tacctgactg aaaaattgcc
    21421 tcaggtggaa ctcaaggtga ccggctttga ctatcagggg gctttggacg aaagggatgt
    21481 gacaggttac gatatagttt cttcttgccg agaatttatc agcgattttg aagaaagagc
    21541 agatgctcag gatttgctgt tcgttacagg gtctctctat tttatctcag aagtacgggg
    21601 ctacctgctg gaccgtgagc agataaattg acccccttgt ttgaacttgt tatactaggg
    21661 gaattgctgg ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt catcatgaaa
    21721 ttaaaaagat tcacactttc tcttgcttct ctagcaagtt ttagtctctt agtagcttgt
    21781 tcacaaagag ctcaacaggt tcaacagcct gttgctcagc agcaggtcca acagcctgct
    21841 caacaacctg ctcaacagaa taccaatact gcaaatgcag gaggtaacca aaatcaagcg
    21901 gctccagtac aaaaccaacc tgttgctcaa ccgaccgata ttgatgggac ttatactggt
    21961 caggatgacg gagaccgtat cactttagtg gtaactggaa cgactggtac atggactgag
    22021 ctcgaatctg acggggatca gaaagtcaaa caggttacat ttgattcagc aaatcaacgc
    22081 atgattattg gcgatgatgt caaaatttac actgtaaacg gtaatcaaat cgtcgtagat
    22141 gatatggata gagacccatc ggaccaaatc gttttaacta aataagacta tgcaagtaga
    22201 aagggctgga tttttcagcc tttttacttt tacctagaaa ataatcataa atacttgcct
    22261 tctaccgaat acctgcgtta tactagtatc aattacttgt ttttagcatt caaactatca
    22321 aggaggggat atgaaatata ggaaatttca attattgatg tccaagtatg gctttagtct
    22381 ttcgattatg ttacttgaac tttgtcttgt ttttggtctc tttctttatt taggacgcat
    22441 ggctcccatt ttatggatta ctgtcctcat tctactgagt atcatcacaa tcatttcgat
    22501 agtcaaccgt aatacgactc ctgagaataa ggtaacctgg ttgttagtag cctttgtgcc
    22561 agtatttggt cccttgctct atctgatgtt tggtgaaagg cgattgtcca aaaaagaaat
    22621 caaacaactg aagaagctag gctctatgca tttccaagaa gcaaatagcc agctactaaa
    22681 agagaaatta aaagaaagtg acaaggcagc ttatggagtc atcaagtcct tattgagtat
    22741 ggataccaat gctgacatct atgatcaaac tgcctctaca ttttttccta acggagaagc
    22801 tatgtggaaa aagatggtag aagatcttaa aaaggctgag aaatttattt tcttggaata
    22861 ttacattata gaagaaggtt tgatgtggaa tcgcatacta gatatactag agcaaaaggt
    22921 agctcagggt gtagaggtta agatgctcta tgatgatatc ggctgtatgg ctactttaac
    22981 aggagattat gcacatcgac ttcgtcagct gggcatcgag gcccataaat tcaataaagt
    23041 tattcctcgt ttgacagtgg cttataataa cagagatcat agaaaaatat tgattgttga
    23101 tggtcagata gcctatactg gtgggatcaa tctggcagat gagtacatta accacgtcga
    23161 gagatttggt tattggaagg atagtggaat tcgcttagac ggactagcag taaaagctct
    23221 gacacgctta tttttgacca cttggtacat taatcgagga gaaattagtg attttgatca
    23281 atatcattta gaaaatcatt ctatcccgag tgacggttta accattccat acggaagtgg
    23341 acccaagcca atttttcgag cgcaggtagg gaaaaaagtt tatcagagtt taatcaatca
    23401 agcaacagaa tcggtctata ttacgacacc ttatttgatt atagattatg atttaacaga
    23461 gacaatcaaa aatgcagcta tgagaggggt cgatgttcga attatcaccc cttacatacc
    23521 agataagaag ttcattcagt tagtcacgag aggagcttat cccgaccttc tttctgctgg
    23581 tgttcggatt tatgagtata gtccaggttt tattcatagt aagcagatgt tggtagacga
    23641 agattttgcg gtggtgggga caatcaatct cgactaccgg agcttggtac accattatga
    23701 aaatgcagtc ttactctata aaactccttc tataagggaa atcgcccgag attttcgaaa
    23761 tatatttgca gattctcagg aagtctatcc tcattctatc aaaacgagct ggtatcaaaa
    23821 gcttgtaaaa gaaatcgccc agctattcgc ccctatctta taagaaatct agaacttagg
    23881 atacaaacca gacctatttt tcttgtcttt tacgaataga aagaaagagg aggggaattc
    23941 atgctaacta aggaagaagt gaatgatatg attgagttca aacagacaca tttacaccgc
    24001 tttcgggaaa ttgaaacctt tgtgaaacta tgcaaaaaat cactcaaaca gccatcgcaa
    24061 gctgacaatc ctaggacttt ttgatatact aagacagata aattgaacag gagaaacgat
    24121 atgagtgtgt atggtagagt agaagaagtt cataaggaga atcgtgaacc tctagaatac
    24181 caaatcgaac aagaatcgca tcatcgtgaa tcaagtcgtc ttcctttggt gaaaatttta
    24241 ctatggagta cgcttgtaac ggggataact ctaggagtac cgctattact cgacttaatg
    24301 agtgcacaag aagtgcagga tttttatgca ggttgggcgc ttcatcagac agggaagatt
    24361 tacagcgact attatggaag tcaaggtttg ctttattatt tgctgactta cgtgagtcag
    24421 ggcggatttt tctttgccat ctttgagtgg ttagccttgg tagcaggagg atttttcctt
    24481 tttagatcag cggacacctt gacagagcaa ggagaccaag ctggacatct ggtgactatt
    24541 ttttacatgc tagttacagg tcttgctttt ggtggaggct atgcgactct tttagcgctt
    24601 cctttcttat tcgcagcctt tagtttagtt gcggcttacc taagcaatcc aagccatgat
    24661 aagggatttg tacggattgg gctagctttg gcaggcggat ttttctttgc tcccttatca
    24721 tcgctcctgt ttattgctgt agtgagttta ggcttgttgg tctttaacct tgggcataga
    24781 cgctttgcgc atgggtttta tcagtttctt gcagtggctt taggtttttc acttgtcttt
    24841 tatccaactg cctactatag tgctgcaaca ggaagttttg gggatgcgat tagtggtatt
    24901 cgttatccta ttgacagtat tcgctttgat tttacttcta aaattttaga gaatatgttt
    24961 ttttatggct tgttgtccct tggtttggga tttgtggttt gtatcttttt aggtctcttt
    25021 caatccaaac cctttaaact atacgtcatt tcggttcctg caagtcttgt ggtaatttta
    25081 ggtttgattt tacttttctt ttcacaagag cctctgcacg cttcttattt gatggtcgtc
    25141 ttccctgttt tcctactttt attggtaacc aatattaaga gtcaacagag ggggcgtagt
    25201 gctagaagaa gccgaagaga aacgccagtt agcctatgga gtcgtttctt caaaggaaat
    25261 ctatatctgc tagtttttga gtttgtctat cttttgtctg ttcctttttt gatgaagttt
    25321 gtcctttatc cagtacctta tcaagaacgt aatcgtcttg ctgatttggt aaaagaggag
    25381 acaaatacgg aagatgctat ctatgcatgg gatgatactg cgactcttta tcgtaagagt
    25441 gagcgcttgt cgccatcggc gattttgtcc ccgttgcact atacagcaac tgaggaaaat
    25501 cgtaataagt tacttaatga cttgaaagaa aaacaaccta aggtgattgt ggtaaatgat
    25561 aaggtggtag tctggtctga agtggaaaca ctcttaaaag aaaattacca acaagtaaag
    25621 actgattact cagagtttaa agtctataaa attaaataac caaatcaata tcttgtgtat
    25681 ttttaaaaat tttaggattt ttaacacaag atattgattt ttctttttag agtggtataa
    25741 tactttttag aaagaacatt ttagaaaaga gcatgcatat gattgcacta gaagaaaaaa
    25801 ttacaatttt gccaactctc ttcgtcgaga aacgagatgg gagacgtgtt gtatttgatg
    25861 tggacaagat tgacaaggct ctccacaagg cggctgacaa ggttatggat gtgacacccc
    25921 tggttgaaaa acgcctcaat gatctgactg agcgaattat tacagaaatt catagtcgct
    25981 ttccacaggg aattaagatt tacgaaattc aaaatatcgt agaacatgaa ctccttgaag
    26041 ccaaagaata tgcgctggct gaggagtata ttacttatcg gacacagagg gattttgagc
    26101 gctcaaaagc gacggatatc aactttagta ttcataaact tctcaacaaa gaccagacag
    26161 ttgtcaatga aaacgctaat aaagacagtg atgtctttaa cactcagcgt gatttgacag
    26221 cagggattgt tgggaaatca atcggactgc aaatgcttcc taagcacgta gccaatgccc
    26281 accaaaaggg ggatatccac tatcacgatt tggactacag tccctatacc cctatgacca
    26341 actgctgttt gattgatttt aagggtatgt tggaaaatgg ttttaagatt ggaaatgcag
    26401 aggtagagag tcccaagtct atccagactg cgacagcaca gatttctcaa atcattgcca
    26461 acgttgcttc tagccagtac ggtggctgtt cagctgaccg tatcgatgaa attttggcgc
    26521 cttatgcaga gaagaattat caaaaacatc tcaaagatgc agaagagtgg gtattgcctg
    26581 aaaaacggga agattacgct tggaagaaaa cgcaaaagga catctacgat gccatgcaat
    26641 ctcttgagta tgaaatcaat actctcttca cttcaaatgg acaaacacct tttacttcgt
    26701 taggttttgg tctgggaacc agtcgttttg aacgagaaat tcaaaaagct attttaaaca
    26761 ttcgcatcaa gggtcttggt tcagaacacc gtacggctat ctttcctaaa cttattttca
    26821 ctctgaaaag aggccttaat ttagaggaag gaactcccaa ctacgacatc aagcagttgg
    26881 ctcttgagtg tgcaaccaaa cggatgtatc cagatgtttt atcttacgat aagattgttg
    26941 acttgacagg atccttcaag gtgcctatgg gttgccgttc tttcctccaa ggatggaagg
    27001 atgaaaatgg tgtagaagtc aattcaggtc gcatgaatct gggtgttgtg acggttaatc
    27061 tgcctcgtat tgctcttgag tctgaaggtg atatgaataa gttctgggaa atcttcaacg
    27121 agcgaatgaa tatcgcagaa gatgctcttg tttaccgtgt cgaacgcact aaagaggcga
    27181 caccagcaaa tgctcctatt ctttatcagt acggtgcttt tggccatcgt ctaggtaaag
    27241 aagaaagtgt tgaccagctc tttaagaatc gtcgtgctac cgtttcgctg ggctatatcg
    27301 gcttgtatga agtagcgaca gttttctttg gtaacagctg ggaaagtaat ccagatgcta
    27361 aggaattcac gctagacatc attcacgata tgaaacgccg tgtagaagag tggtcagacc
    27421 aatatggcta ccatttctct atctactcaa caccatccga aagtctgaca gaccgtttct
    27481 gccgactaga tatagacaag tttggctcta ttcctgatat cacagacaag gaatactaca
    27541 ccaactcttt ccactacgat gttcgtaaaa atccaacacc gtttgaaaaa ttggactttg
    27601 agaaagtcta tccagaagca ggtgcgtcag gtggtttcat ccattattgt gagtatccag
    27661 tccttcagca aaatccaaag gccttggaag ctgtctggga ttatgcttat gaccgtgtag
    27721 gctatctagg caccaatact ccgattgacc gttgctacaa gtgtgacttt gaaggggatt
    27781 ttgaaccaac tgagagaggg tttgcttgtc caaactgtgg caatagcgac cctaaaacag
    27841 tagatgtggt gaagcgaact tgtggctacc taggtaatcc tcaagcaaga ccgatggtca
    27901 acgggcgtca caaggaaatc gctgcgcgtg tcaaacatat gaatggttca acgattaaaa
    27961 tagctgggca tcaagtaaca aattagaaag aaatgaaatg ggaaaatatc aactagacga
    28021 taaggggcgc gcacaagtga cccgttatca cgagaaacac tctaaaggtg gagctggtaa
    28081 gaaagaacgc ttgcttagct tcagagaaca atttttaaac aagaacaaga aaaaataaaa
    28141 gtgagagcca gctctcgctt ttctcatagt gggaggtaag gatggaatta cgcagaccaa
    28201 gattagcgga taagaaagct gttttagata tgatgacaga gtttgaaaag agtcaatcag
    28261 cccatgatgg aggattttgg gatgttgagg atttttctta cgaggagtgg ctagaaggta
    28321 accgtaataa agaaatggga atatggctac ctgaaaatcg cgttccatcg atacagttcg
    28381 tattgtttgg tgaatcaggt tgtgctctag gatttttgaa tctgcgattg agactgaatg
    28441 aggggttact gaattatgct ggccacattg gctactccat ccgtccatct gaaagaggca
    28501 agggttatgc aaaagagact ctccgtcagg gcttgcaagt tgctaaggaa aagaacatca
    28561 agaaagctct ggtgacctgt agcgtgaata atcttgctag cagagcagtc attctagcaa
    28621 atggtggaat atttgaggat gctcgcaatg gagtcgagcg ttattggata gaggtagcga
    28681 atgaataatc caaaaccaca agaatggaaa agcgaggaac ttagtcaagg tcgtatcatt
    28741 gactacaagg cctttaactt tgtggacggc gaaggcgtgc gtaactctct ctatgtatca
    28801 ggctgtatgt ttcactgcga gggatgttat aatgttgcga cttggtcttt taatgctggc
    28861 attccctata cagcagaatt agaagagcag atcatggcag atcttgctca gccctatgtt
    28921 caaggtttga ctttgttggg aggggagcct tttcttaata ctgggattct cttgccactt
    28981 gttaagcgga ttcggaagga attgccagac aaggacatct ggtcctggac cggctacact
    29041 tgggaagaaa tgatgttgga aactccagat aaactggaat tcttgtcact gattgacatt
    29101 cttgtcgatg gaagatatga tcgaactaag agaaatctta tgctccagtt tcgaggttcg
    29161 tctaaccaac gaattatcga tgtgcaaaaa tcgctcaaaa gtgggcaagt agtgatttgg
    29221 gacaagctca atgacggaaa agaaagctat gaacaggtga agagagaatg aagaaaaaag
    29281 acttagtaga ccaactagtc tcagagatcg agacggggaa agtcaggaca ctgggaatat
    29341 acggtcatgg agcttcaggt aaatcaacct ttgcacagga attgtaccaa gctttagatt
    29401 ctactacagt aaatttgcta gagacagatc cttatatcac ctcaggacgc catctggtag
    29461 tacccaagga cgcgccgaat caaaaggtga cagccagtct gccagtggcg catgaactgg
    29521 agagtttgca gagagatatc cttgccttgc aggcgagtat ggatgtcttg acaattgaag
    29581 aaccttggaa ggctagtgag gtcttgtctg gagccaaacc aattttgatt gtcgaaggga
    29641 tgtctgttgg ctttctaccc aaggaactct ttgaaaaaac catctgtttc tacacggatg
    29701 aggagaccga attaaagcga cgccttgcta gagatacgac tgtgagaaat cgcgatgcat
    29761 cctttatatt ggctagccat cagatgagac gggagcagta tctgcgatac tataaagaaa
    29821 ctgagtctaa ggcggatatc ttagtggacc aatcagaaga taaatttgat gtcaagagga
    29881 cttaacttat gtatagaaga aatatagaag aaaatcccta attttagaaa gaaaaagtag
    29941 gaaaacagtt tcatccccaa aaaacgaaaa aacctaacaa atcccttgca atcgcagggg
    30001 atttgtgtta ttctattatg gtgctgtaaa ttacagcctt agttttgatg caagaggttg
    30061 cgacacgctc ggttgcattg ccacgcaaca ccgcgtcggt tttcttgtgg agctagccta
    30121 ttatcttaaa tagacgaaaa ggagaaaaag atggcaaaca aaaaaatccg tatccgtttg
    30181 aaagcttacg aacaccgtac gcttgacaca gcggctgcaa aaatcgtaga atcagctact
    30241 cgtacaggtg cacaagttgc gggtccaatc ccacttccaa ctgaacgtag cctctacaca
    30301 atcattcgtg cgactcacaa atacaaagac tctcgcgaac aatttgaaat gcgtacacac
    30361 aaacgtttga tcgatatcgt taacccaact caaaaaacag ttgatgcctt gatgaaattg
    30421 gatcttccaa gtggtgtaaa cgtagaaatc aaactttaat ctaaaatata aaagagcaga
    30481 ggctggtgtt tcaatctaat tgaacacggg ctaaactcgg tgtgaaaaag ataaacttcc
    30541 tcgcgtctgc tagacactgt gtcagtttcc tattttcact ttgagtttga cgccctttgt
    30601 atcttagact tgagcataaa aaacgctcgt taaaaacttt ttgaataaaa aatatagaaa
    30661 aggaactatt ttctcatgac aaaaggaatc ttagggaaaa aagtgggaat gactcaaatc
    30721 ttcactgaag ctggcgaatt gatccctgta acagttattg aagcaactcc aaacgttgtt
    30781 cttcaagtta aaactgttga aacagacgga tacaacgcta tccaagttgg tttcgatgac
    30841 aaacgcgaag tattgagcaa caaacctgct aaaggacatg tagcgaaagc taacacggct
    30901 cctaagcgct tcattcgtga attcaaaaac gttgaaggct tggaagttgg tgctgaaatt
    30961 acagttgaaa cattcgcagc tggagacgtt gttgacgtaa ctggtacttc taaaggtaaa
    31021 ggtttccaag gtgttatcaa acgccacgga caatcacgtg gaccaatggc tcacggttct
    31081 cgttaccacc gtcgtccagg ttctatggga cctgttgcac ctaaccgcgt attcaaaggt
    31141 aaaaaccttg caggacgtat gggtggtgac cgcgtaacaa ttcaaaatct tgaagttgta
    31201 caagttgttc cagaaaagaa cgttatcctt atcaaaggta acgtaccagg tgctaagaaa
    31261 tctcttatca ctatcaaatc agcagttaaa gctggtaaat aataaagaaa ggggaaatca
    31321 gtcacaatgg caaacgtaac attatttgac caaactggta aagaagctgg ccaagttgtt
    31381 cttagcgatg cagtatttgg tatcgaacca aatgaatcag ttgtgtttga tgtaatcatc
    31441 agccaacgcg caagccttcg tcaaggaaca cacgctgtta aaaaccgctc tgcagtatca
    31501 ggtggtggac gcaaaccatg gcgtcaaaaa ggaactggac gtgctcgtca aggttctatc
    31561 cgctcaccac aatggcgtgg tggtggtgtt gtcttcggac caactccacg ttcatacggc
    31621 tacaaacttc cacaaaaagt tcgtcgccta gctcttaaat cagtttactc tgaaaaagtt
    31681 gctgaaaaca aattcgtagc tgtagacgct ctttcattta cagctccaaa aactgctgaa
    31741 tttgcaaaag ttcttgcagc attgagcatc gattctaaag ttcttgttat ccttgaagaa
    31801 ggaaatgaat tcgcagctct ttcagctcgt aaccttccaa acgtgaaagt tgcaactgct
    31861 acaactgcaa gtgttcttga catcgcaaat agcgacaaac ttcttgtcac acaagcagct
    31921 atctctaaaa tcgaggaggt tcttgcataa tgaatttgta tgatgttatc aaaaaacctg
    31981 tcatcactga aagctcaatg gctcaacttg aagcagggaa atatgtattt gaagttgaca
    32041 ctcgtgcaca caaacttttg atcaagcaag ctgttgaagc tgctttcgaa ggtgttaaag
    32101 ttgccaatgt taacacaatc aacgtaaaac caaaagctaa acgtgttgga cgttacactg
    32161 gttttactaa caaaactaaa aaagctatca tcacacttac agctgattct aaagcaatcg
    32221 agttgtttgc tgctgaagct gaataatcta aggaggaaat atcgtgggaa ttcgtgttta
    32281 taaaccaaca acaaacggtc gccgtaatat gacttctttg gatttcgctg aaatcacaac
    32341 aagcactcct gaaaaatcat tgcttgttgc attgaagagc aaggctggtc gtaacaacaa
    32401 cggtcgtatc acagttcgtc accaaggtgg tggacacaaa cgtttctacc gtttggttga
    32461 cttcaaacgt aataaagaca acgttgaagc agttgttaaa acaatcgagt acgatccaaa
    32521 ccgttctgca aacatcgctc ttgtacacta cactgacggt gtgaaagcat acatcatcgc
    32581 tccaaaaggt cttgaagtag gtcaacgtat cgtttcaggt ccagaagcag atatcaaagt
    32641 cggaaacgct cttccacttg ctaacatccc agttggtact ttgattcaca acatcgagtt
    32701 gaaaccaggt cgtggtggtg aattggtacg tgctgctggt gcatctgctc aagtattggg
    32761 ttctgaaggt aaatacgttc ttgttcgtct tcaatcaggt gaagttcgta tgattcttgg
    32821 aacttgccgt gctacagttg gtgttgtcgg aaacgaacaa catggacttg taaaccttgg
    32881 taaagcagga cgtagccgtt ggaaaggtat ccgcccaaca gttcgtggtt ctgtaatgaa
    32941 ccctaacgat cacccacacg gtggtggtga aggtaaggca ccagttggtc gtaaagcacc
    33001 atctactcca tggggcaaac ctgctcttgg tcttaaaact cgtaacaaga aagcgaaatc
    33061 tgacaaactt atcgttcgtc gtcgcaacga gaaataatat taaactagtc gcttaagcaa
    33121 ctagtaaatc cgccagctcg gtagcgctcc ataggagtgc aagccgctgt ggtacaacat
    33181 ttaaaggaga aaatataaaa atgggacgca gtcttaaaaa aggacctttc gtcgatgagc
    33241 atttgatgaa aaaagttgaa gctcaagcta acgacgaaaa gaaaaaagtt attaaaactt
    33301 ggtcacgtcg atcaacgatc ttcccaagtt tcattggtta cactattgca gtttatgacg
    33361 gacgtaaaca cgtacctgtt tacatccaag aagacatggt aggccacaaa cttggtgaat
    33421 ttgcaccaac tcgtacttac aaaggtcacg ctgcagacga caagaaaaca cgtagaaaat
    33481 aaggagaaca taaatggcag aaattacttc agctaaagca atggctcgta cagtacgtgt
    33541 ttcacctcgt aaatcacgtc ttgttcttga taacatccgt ggtaaaagcg tagccgatgc
    33601 aatcgcaatc ttgacattca ctccaaacaa agctgctgaa atcatcttga aagttttgaa
    33661 ctcagctgta gctaacgctg aaaacaactt tggtttggat aaagctaact tggtagtatc
    33721 tgaagcattc gcaaacgaag gaccaactat gaaacgtttc cgtccacgtg cgaaaggttc
    33781 agcttcacca atcaacaaac gtacagctca catcactgta gctgttgcag aaaaataagg
    33841 aggtaaaatc gtgggtcaaa aagtacatcc aattggtatg cgtgtcggca tcatccgtga
    33901 ttgggatgcc aaatggtatg ctgaaaaaga atacgcggat taccttcatg aagatcttgc
    33961 aatccgtaaa ttcgttcaaa aagaacttgc tgacgcagca gtttcaacta ttgaaatcga
    34021 acgcgcagta aacaaagtta acgtttcact tcacactgct aaaccaggta tggttatcgg
    34081 taaaggtggt gctaacgttg atgcactccg tgcaaaactt aacaaattga ctggaaaaca
    34141 agtacacatc aacatcatcg aaatcaaaca acctgatttg gatgctcacc ttgtaggtga
    34201 aggaattgct cgtcaattgg agcaacgtgt tgctttccgt cgtgcacaaa aacaagcaat
    34261 ccaacgtgca atgcgtgctg gagctaaagg aatcaaaact caagtatcag gtcgtttgaa
    34321 cggtgcagat atcgcccgtg ctgaaggata ctctgaagga actgttccgc ttcacacact
    34381 tcgtgcagat atcgattacg cttgggaaga agcagatact acatatggta aacttggtgt
    34441 taaagtatgg atctaccgtg gtgaagttct tccagctcgt aaaaacacta aaggaggtaa
    34501 ataaccaatg ttagtaccta aacgtgttaa acaccgtcgt gaattccgtg gaaaaatgcg
    34561 cggtgaagca aaaggtggaa aagaagtagc attcggtgaa tacggtcttc aagctacaac
    34621 tagccactgg atcactaacc gccaaatcga agctgctcgt atcgccatga ctcgttacat
    34681 gaaacgtggt ggtaaagttt ggattaaaat cttcccacac aaatcataca ctgctaaagc
    34741 tatcggtgtg cgtatgggat ctggtaaagg ggcacctgaa ggttgggtag caccagttaa
    34801 acgtggtaaa gtgatgttcg aaatcgctgg tgtatctgaa gagattgcac gtgaagcgct
    34861 tcgacttgct agccacaaat tgccagttaa atgtaaattc gtaaaacgtg aagcagaata
    34921 aggagaaggc atgaaactta atgaagtaaa agaatttgtt aaagaacttc gtggtctttc
    34981 tcaagaagaa ctcgcgaagc gcgaaaacga attgaaaaaa gaattgtttg aacttcgttt
    35041 ccaagctgct actggtcaat tggaacaaac agctcgcttg aaagaagtta aaaaacaaat
    35101 cgctcgtatc aaaacagttc aatctgaagc gaaataatag actagggaag gagaaatttc
    35161 aatggaacgc aataatcgta aagttcttgt tggacgtgtt gtatctgaca aaatggacaa
    35221 gacaatcaca gttgtagttg aaacaaaacg taaccaccca gtctatggta aacgtattaa
    35281 ctactctaaa aaatacaaag ctcatgatga aaacaatgtt gccaaagaag gcgatatcgt
    35341 acgtatcatg gaaactcgcc cgctttcagc tacaaaacgt ttccgtcttg tagaagttgt
    35401 tgaagaagcg gtcatcatct aatcaaacct gaaaggagaa aactgaaatg attcaaacag
    35461 aaactcgttt gaaagtcgca gacaacagcg gtgctcgcga aatcttgact atcaaagttc
    35521 ttggtggttc aggacgtaaa tttgcaaaca tcggtgatgt tatcgtggca tctgtaaaac
    35581 aagctactcc tggtggtgcg gttaaaaaag gtgacgttgt taaagcagtt atcgttcgta
    35641 ctaaatcagg tgctcgtcgt gctgatggtt catacatcaa atttgacgaa aacgcagcag
    35701 ttatcatccg tgaagacaaa actcctcgcg gaacacgtat ctttggccca gttgcacgtg
    35761 aattgcgtga aggtggcttc atgaagatcg tgtcacttgc tccagaagta ctttaatttt
    35821 taggaacaaa ctagtcccct agcttcaagc tagggtgccc ttatgggcgt aagaaaaatc
    35881 aaggagaaac ctaatgtttg taaaaaaagg cgacaaagtt cgcgtaatcg ctggtaaaga
    35941 taagggaaca gaagctgttg tccttactgc ccttccaaaa gtaaacaaag ttatcgttga
    36001 aggtgttaac attgttaaga aacaccaacg tccaactaac gagcttcctc aaggtggtat
    36061 catcgagaaa gaagcagcta tccacgtatc aaatgttcaa gttttggata aaaatggtgt
    36121 agctggtcgt gttggttaca aatttgtaga cggtaaaaaa gttcgctaca acaaaaaatc
    36181 aggcgaagtg cttgattaat cacgaaggaa aggagaagta taatggcaaa tcgtttaaaa
    36241 gaaaaatatc ttaatgaagt agttcctgct ttgacagaac aattcaacta ctcatcagtg
    36301 atggctgtgc ctaaagtaga taagattgtt ttgaacatgg gtgttggtga agctgtatca
    36361 aacgctaaaa gccttgaaaa agctgctgaa gaattggcac ttatctcagg tcaaaaacca
    36421 cttatcacta aagctaaaaa atcaatcgcc ggcttccgtc ttcgtgaagg tgttgcgatc
    36481 ggtgcaaaag ttacccttcg tggtgaacgt atgtacgaat tcttggataa attggtatca
    36541 gtttcacttc cacgtgtacg tgacttccac ggtgtcccaa caaaatcatt tgatggacgc
    36601 gggaactaca cacttggtgt gaaagaacaa ttaatcttcc cagaaatcaa cttcgatgac
    36661 gttgacaaaa ctcgtggtct tgacatcgtt atcgtaacaa ctgctaacac tgacgaagag
    36721 tcacgtgcat tgcttacagg ccttggaatg ccttttgcaa aataatatag gaggtaaatc
    36781 taatggctaa aaaatcaatg gtagctagag aggctaaacg ccaaaaaatt gttgaccgtt
    36841 atgctgaaaa acgtgctgca ttaaaggcgg caggggacta cgaaggttta tctaaattac
    36901 ctcgcaacgc ctcaccgact cgtttacata atcgttgtag ggttacgggg cgcccacatt
    36961 cagtttaccg caaatttggt ctgagtcgta tcgcttttcg cgaacttgcg cataaaggtc
    37021 aaattcctgg tgtaacaaaa gcatcttggt aatttaagat atcaagagtg tcaaaactcc
    37081 aagtaaaaat aggaaacttg acgaagaaac taaagtttct aggaaagttt atctttttca
    37141 cacagagttt agcccgggtt caattgggct tgccaatttg aacacgagct acagctttgg
    37201 caaaaaagac caatttgctt tggagcattg cttctgcatt aaattgtcta tttttgctcg
    37261 tgctgttacg ctctttgtat catgtattaa ctagcaagtg caacttgcaa actactagta
    37321 agaggagaaa aacaaaatgg ttatgactga cccaatcgca gacttcctaa ctcgtattcg
    37381 taatgctaac caagctaaac acgaagtact tgaagtacct gcatcaaaca tcaaaaaagg
    37441 gattgctgaa atccttaaac gcgaaggttt tgtaaaaaac gttgaaatca ttgaagatga
    37501 caaacaaggc gtcatccgtg tatttcttaa atacggacca aatggtgaga aagttatcac
    37561 taacttgaaa cgtgtttcta aaccaggact tcgtgtctac aaaaaacgtg aagaccttcc
    37621 aaaagttctt aacggacttg gaattgccat cctttcaact tctgaaggtt tgcttactga
    37681 taaagaagca cgccaaaaga atgttggtgg tgaggttatc gcttacgttt ggtaaaatca
    37741 agatacaaag ctcgtaaaga acaaagcaaa attaggaagt tggagaagtt tgtttacaaa
    37801 caagccaact tatctatttt gcacagttct tagagcgtgt tcagttcagc tcttgaacta
    37861 aataagtatc tgaaccccgt gaaaactggc cgttctggcc tgacaattta acaggagaaa
    37921 ataaacatgt cacgtattgg taataaagtt atcgtgttgc ctgctggtgt tgaactcgct
    37981 aacaatgaca acgttgtaac tgtaaaagga cctaaaggag aacttactcg tgagttctca
    38041 aaagatattg aaatccgtgt ggaaggtact gaaataactc ttcaccgtcc aaacgattca
    38101 aaagaaatga aaactatcca cggaactact cgtgcccttt tgaacaacat ggttgttggt
    38161 gtatcagaag gattcaagaa agaacttgaa atgcgtgggg ttggttaccg tgcacagctt
    38221 caaggatcta aacttgtttt ggctgttggt aaatctcatc cagacgaagt tgaagctcca
    38281 gaaggaatta cttttgaact tccaaaccca acaacaatcg ttgttagcgg aatttcaaaa
    38341 gaagtagttg gtcaaacagc tgcttacgta cgtagccttc gttcaccaga accatataaa
    38401 ggtaaaggta tccgttacgt tggtgaattc gttcgccgta aagaaggtaa aacaggtaaa
    38461 taatgttgag tggttgatca tcaaccacca acctattttc caactttgtg catagcacac
    38521 gatttaaaac taaagaggtg aaaactgtga tttcaaaacc agataaaaac aaactccgcc
    38581 aaaaacgcca ccgtcgcgtt cgcggaaaac tctctggaac tgctgatcgc ccacgtttga
    38641 acgtattccg ttctaataca ggcatctacg ctcaagtgat tgatgacgta gcgggtgtaa
    38701 cgctcgcaag tgcttcaact cttgataaag aagtttcaaa aggaactaaa actgaacaag
    38761 ccgttgctgt cggtaaactc gttgcagaac gtgcaaacgc taaaggtatt tcagaagtgg
    38821 tgttcgaccg cggtggatat ctatatcacg gacgtgtgaa agctttggct gatgcagctc
    38881 gtgaaaacgg attgaaattc taataggagg acactagaaa atggcattta aagacaatgc
    38941 agttgaatta gaagaacgcg tagttgctgt caaccgtgtt acaaaagttg ttaaaggtgg
    39001 acgtcgtctt cgtttcgcag ctcttgttgt tgttggtgac cacaatggtc gcgtaggatt
    39061 tggtactggt aaagctcaag aagttccaga agcaatccgt aaagcagtag atgatgctaa
    39121 gaaaaacttg atcgaagttc ctatggttgg aacaacaatc ccacacgaag ttctttcaga
    39181 attcggtgga gctaaagtat tgttgaaacc tgctgtagaa ggttctggag ttgccgctgg
    39241 tggtgcagtt cgtgccgttg tggaattggc aggtgtggca gatattacat ctaaatcact
    39301 tggttctaac actccaatca acattgttcg tgcaactgtt gaaggtttga aacaattgaa
    39361 acgcgctgaa gaaattgctg cccttcgtgg tatttcagtt tctgatttgg cataagaaag
    39421 gggataaaat ggctcaaatt aaaattactt tgactaagtc tccaatcgga cgcattccat
    39481 cacaacgtaa aactgttgta gcacttggac ttggcaaatt gaacagctct gttattaaag
    39541 aagataacgc tgctatccgt ggtatgatca cagcagtatc tcacttagta acagttgaag
    39601 aagtaaacta atgaagtttt aggggatgtg cactgtacca tcccctaaaa ctagatatag
    39661 tcatctatga tgacatcgta taggcgagtt gatgggggag acaacctttt ctcccttatc
    39721 ggcgctagca ttttacaaaa gaggagaaaa taaaaatgaa acttcatgaa ttgaaacctg
    39781 cagaaggttc tcgtaaagta cgtaaccgcg ttggtcgtgg tacttcatca ggtaacggta
    39841 aaacatctgg tcgtggtcaa aaaggtcaaa aagctcgtag cggtggcgga gttcgccttg
    39901 gttttgaagg tggacaaact ccattgttcc gtcgtcttcc aaaacgtgga ttcactaaca
    39961 tcaacgctaa agaatacgca attgtgaacc ttgaccaatt gaacgtcttt gaagatggtg
    40021 ctgaagtaac tccagttgtt cttatcgaag caggaattgt taaagctgaa aagtcaggta
    40081 ttaaaattct tggtaacggt gagttgacta agaaattgac tgtgaaagca gctaaattct
    40141 ctaaatcagc tgaagaagct atcactgcta aaggtggttc agtagaagtc atctaagaga
    40201 ggtgacctat gttttttaaa ttattaagag aagctcttaa agtcaagcag gttcgatcaa
    40261 aaattttatt tacaattttt atcgttttgg tctttcgtat cggaactagc attacagttc
    40321 ctggtgtgaa tgccaatagc ttgaatgctt taagtggatt atccttctta aacatgttga
    40381 gcttggtgtc ggggaatgcc ctaaaaaact tttcgatttt tgccctagga gttagtccct
    40441 atatcactgc ttctattgtt gtccaactct tgcaaatgga tattttaccc aagtttgtag
    40501 agtggggtaa acaaggggaa gtaggtcgaa gaaaattgaa tcaagctact cgttatattg
    40561 ctctagttct cgcttttgtg caatctatcg ggattacagc tggttttaat accttggctg
    40621 gagctcaatt gattaaaact gctttaactc cacaagtttt tctgacgatt ggtatcatct
    40681 taacagctgg tagtatgatt gtcacttggt tgggtgagca aattacagat aagggatacg
    40741 gaaacggtgt ttccatgatt atctttgccg ggattgtttc ctcaattcca gagatgattc
    40801 agggcatcta tgtggactac tttgtgaacg tcccaagtag ccgtatcact tcatctatca
    40861 ttttcgtaat cattttgatt attactgtat tgttgattat ttactttaca acttatgttc
    40921 aacaagcaga atacaaaatt ccaatccaat atactaaggt tgcacaaggt gctccatcta
    40981 gctcttacct tccgttaaag gtaaatcctg ctggagttat ccctgttatc tttgccagtt
    41041 cgattactgc agcgcctgcg gctattcttc agtttttgag tgccacaggt catgattggg
    41101 cttgggtaag ggtagcacaa gagatgttgg caactacttc tccaactggt attgccatgt
    41161 atgctttgtt gattattctc tttacattct tctatacgtt tgtacagatt aatcctgaaa
    41221 aagcagcaga gagcctacaa aagagtggtg cctatatcca tggagttcgt cctggtaaag
    41281 gtacagaaga atatatgtct aaacttcttc gtcgtcttgc aactgttggt tccctcttcc
    41341 ttggtgtgat ttccatttta ccgattgcag ctaaagatgt atttggtctt tctgatgttg
    41401 ttgcctttgg tggaacaagt ctcttgatca ttatctctac aggtatcgaa ggaatcaagc
    41461 aattggaagg ttacctattg aaacgtaagt atgttggttt catggacaga acagaataaa
    41521 agtatttact gaatcagtaa atgctgaggg agtggaggtt taaactctga catttgtaag
    41581 agttggatct cccctcttct attttgtttt taaatagggg tgaaaagact ttttgcttct
    41641 atttaaaaat aaaataagga gatcaaatca tgaatctttt gattatgggc ttacctggtg
    41701 caggtaaggg aactcaagca gcaaaaatcg tagaacaatt ccatgttgca catatctcaa
    41761 caggtgatat gttccgcgct gcaatggcaa atcaaactga aatgggtgtt cttgctaagt
    41821 catatattga caagggtgaa ttggttcctg acgaagttac aaatggaatc gtaaaagaac
    41881 gcctttcaca agatgatatt aaagaaacag gattcttatt ggatggttac ccacgtacaa
    41941 ttgaacaagc tcatgccttg gacaaaacat tggctgaact tggcattgaa ctagaaggtg
    42001 ttatcaatat tgaagtgaac cctgacagcc tcttggaacg tttgagtggc cgtatcatcc
    42061 accgcgtaac tggagaaact ttccacaagg tctttaaccc accagttgac tataaagaag
    42121 aagattacta ccaacgtgaa gatgataagc ctgagacagt aaaacgtcgt ttggatgtta
    42181 atattgctca aggagaacca atcattgctc actaccgtgc caaaggtttg gttcatgaca
    42241 tcgaaggtaa tcaagatatc aatgatgtct tctcagatat tgaaaaagta ttgacaaatt
    42301 tgaaataaag cgtttttcat acttgcaaaa attcgctaca aatgttatac tgagatagtc
    42361 tgacttataa ttgttgtctc tgtgtctaga ggcatcgaat cgaaatttat ggaggtgctt
    42421 ttgcgtggca aaagacgatg tgattgaagt tgaaggcaaa gtagttgata caatgccgaa
    42481 tgcaatgttt acggttgaac ttgaaaatgg acatcagatt ttagcaacag tttctggtaa
    42541 aattcgtaaa aactatattc gtattttagc gggagatcgt gttactgtcg aaatgagtcc
    42601 atatgacttg acacgtggac gtatcactta ccgctttaaa taatcgaaaa acttggaggg
    42661 ataagaaatg aaagtaagac catcggtcaa accaatttgc gaatactgta aagttattcg
    42721 tcgtaatggt cgtgttatgg taatttgccc agcaaatcca aaacacaaac aacgtcaagg
    42781 ataagataga aaggagaaaa catggctcgt attgctggag ttgatattcc aaatgacaaa
    42841 cgcgtagtaa tctcattgac ttatgtttat ggtatcggac ttgcaacatc taagaaaatt
    42901 ttggctgctg ctggaatctc agaagatgtt cgtgtacgtg atcttacatc agatcaagaa
    42961 gatgctatcc gtcgtgaagt ggatgcaatc aaagttgaag gtgaccttcg tcgtgaagta
    43021 aacttgaaca tcaaacgttt gatggaaatc ggttcatacc gtggtatccg tcaccgtcgt
    43081 ggacttcctg tccgtggaca aaacactaaa aacaacgctc gcactcgtaa aggtaaagct
    43141 gttgcgattg ctggtaagaa aaaataatat aggaggtaaa agtcttggct aaaccaacac
    43201 gtaaacgtcg tgtgaaaaag aatatcgaat ctggtattgc tcatattcac gctacattta
    43261 ataacactat tgttatgatt actgatgtgc atggtaatgc aattgcttgg tcatcagctg
    43321 gtgctcttgg tttcaaaggt tctcgtaaat ctacaccatt cgctgctcaa atggcttctg
    43381 aagctgctgc taaatctgca caagaacacg gtcttaaatc agttgaagtt actgtaaaag
    43441 gtccaggttc tggtcgtgag tcagctattc gtgcgcttgc tgccgctggt cttgaagtaa
    43501 cagcaattcg tgatgtgact ccagtgccac acaatggtgc tcgtcctcca aaacgtcgcc
    43561 gtgtataatc atcgcattac actgcttttc gtttaagagg gagtaactaa atgatcgagt
    43621 ttgaaaaacc aaatataaca aaaattgatg aaaataaaga ttatggcaag tttgtaatcg
    43681 aaccacttga acgtggctac ggtacaactc ttggtaactc tcttcgtcgt gtacttctag
    43741 cttctctacc aggagcagct gtgacatcta tcaacattga tggtgtgtta catgagtttg
    43801 acacagttcc aggtgttcgt gaagacgtga tgcaaatcat tctgaacatt aaaggaattg
    43861 cagtgaaatc gtacgttgaa gacgaaaaaa tcatcgaact ggatgttgaa ggtcctgctg
    43921 aagtaacagc tggtgacatt ttgacagata gcgatattga aattgtaaat ccagatcatt
    43981 atctctttac aatcggtgaa ggttcttctc taaaagcgac tatgactgtt aacagtggtc
    44041 gtggatatgt acctgctgat gaaaataaaa aggataatgc accagttgga acacttgctg
    44101 tagattctat ttatacacca gttacaaaag tcaactatca agtggaacct gctcgtgtag
    44161 gtagcaatga tggtttcgac aaattaaccc ttgaaatctt gacaaatgga acaattattc
    44221 cagaagatgc tttagggctt tcagcacgta ttttgacaga acatcttgat ttgtttacaa
    44281 atcttactga gattgctaag tcaactgaag tgatgaaaga agctgatact gaatctgacg
    44341 accgtatttt agatcgtacg attgaggaac tggacttgtc tgtgcgttca tacaactgtt
    44401 taaaacgtgc cggtatcaat actgtgcatg atttgacaga aaaatctgaa gcagagatga
    44461 tgaaagtacg aaatcttgga cgcaagagtt tggaagaagt gaaactcaaa ctcattgatt
    44521 tgggtcttgg attaaaagat aaataaagga ggaatacatg gcttaccgta aactaggacg
    44581 cactagctca caacgtaaag caatgcttcg cgatttgaca actgaccttt tgatcaacga
    44641 atcaatcgtg acaactgaag ctcgtgctaa agaaatccgt aaaactgttg aaaaaatgat
    44701 tactctaggt aaacgtggtg atttgcatgc acgtcgtcaa gcagctgctt tcgtacgtaa
    44761 tgaaatcgca tctgaaaact atgatgaagc aactgataag tacacttcta ctacagcact
    44821 tcaaaaattg ttctcagaaa tcgcacctcg ttatgctgaa cgtaacggtg gatacactcg
    44881 tatccttaaa actgaaccac gtcgtggtga tgcagcgcca atggcgatca tcgaattagt
    44941 ataaaatcat caattttgtt gagtgttatg atgatggagt cttgtgctct tagtctagct
    45001 ctggtctacc gctaggattt cggtcctagc gggaacactc atcataagtt gggatagtag
    45061 acgcttgttt acgaaattgt ttttttctta agaacaactt cgtaagcagg cgtttttgag
    45121 tattttcgtt agaattatgc tatactattt gaaaagaatc ctgtttaatg ttaaggtttc
    45181 ttattttaag aagaattgga gtttacttat gaaagccatt ataactgttg ttggtaaaga
    45241 taaatctgga attgttgcag gtgtttctgg taaaattgca gaattaggat tgaatattga
    45301 cgatatctct caaactgtat tggatgaata ttttacgatg atggctgttg tatctagtga
    45361 tgaaaagcaa gattttacct atcttcgtaa tgaatttgaa gcttttgggc aaactttgaa
    45421 tgtaaaaatc aatattcaga gtgcagcgat tttcgaagct atgtataata tctaggaggt
    45481 catcatggat attagacaag ttactgaaac catcgccatg attgaggagc aaaacttcga
    45541 tattagaacc attaccatgg ggatttctct tttggactgt atcgatccaa atatcaatcg
    45601 tgctgcggag aaaatctatc aaaaaattac gacaaaggcg gctaatttag tagctgttgg
    45661 tgatgaaatt gcggctgagt tgggaattcc tatcgttaat aagcgtgtat cggtgacacc
    45721 tatttctctg attggggcag cgacagatgc gacggactac gtggttctgg caaaagcgct
    45781 tgataaggct gcgaaagaga ttggtgtgga ctttattggt ggtttttctg ccttagtaca
    45841 aaaaggttat caaaagggag atgagattct catcaattcc attcctcgcg ctttggctga
    45901 gacggataag gtctgctcgt cagtcaatat cggctcaacc aagtctggta ttaatatgac
    45961 ggctgtggca gatatgggac gaattatcaa ggaaacagca aatctttcag atatgggagt
    46021 ggccaagttg gttgtattcg ctaatgctgt tgaggacaat ccatttatgg cgggtgcctt
    46081 tcatggtgtt ggggaagcag atgttatcat caatgtcgga gtttctggtc ctggtgtggt
    46141 gaaacgtgct ttggaaaaag ttcgtggaca gagctttgat gtagtagccg aaacagttaa
    46201 gaaaactgcc tttaaaatca ctcgtatcgg tcaattggtt ggtcaaatgg ccagtgagag
    46261 actgggtgtg gagtttggta ttgtggactt gagtttggca ccaacccctg cggttggaga
    46321 ctctgtggca cgtgtccttg aggaaatggg gctagaaaca gttggcacgc atggaacgac
    46381 agctgccttg gccctcttga acgaccaagt taaaaagggt ggagtgatgg cctgtaacca
    46441 ggtcggtggt ctatctggtg cctttatccc tgtttctgag gatgaaggaa tgattgctgc
    46501 agtgcaaaat ggctctctta atttagaaaa actagaagct atgacggcta tctgttctgt
    46561 tggattggat atgattgcca tcccagaaga tacgcctgct gaaactattg cggctatgat
    46621 tgcggatgaa gcagcaatcg gtgttatcaa catgaaaaca acagctgttc gtatcattcc
    46681 caaaggaaga gaaggcgata tgattgagtt tggtggtcta ttaggaactg cacctgttat
    46741 gaaggttaat ggggcttcgt ctgtcgactt catctctcgc ggtggacaaa tcccagcacc
    46801 aattcatagt tttaaaaatt aagaaaatag gagaaatttt aagttctatt taagattaga
    46861 cgtgtatact ataatcatta aataaagacc tcctaatatt atttgaaaca gataacactg
    46921 aattagtttg aatttgattt tcatctaata tctttattta atgaactcct aaactttttc
    46981 ataataatct ccttcaaaag tcgcctgtat gggtggcttt tattttatca ttcatgatat
    47041 aatagaagca aacggaggac ggaaaatggt aaaagtacga ttgtatttgg tacgtcatgg
    47101 caagaccatg tttaacacga ttggtcgcgc gcaaggttgg agcgatactc ccttaactgc
    47161 tgaaggtgaa cgagggattc aagagttagg aattggtttg cgagaatctg atctacagtt
    47221 tgagcgcgct tattcgagtg attctggtcg taccattcag accatgggaa ttatccttga
    47281 agaacttggc ttgcagggga aaatccctta tcgcatggac aagcgtatca gagaatggtg
    47341 tttcggtagt tttgatggag cctatgatgg cgatcttttc atgggcatta ttcctcgtat
    47401 ctttaatgtg gaccacgttc accaattgtc ttatgctgaa ctggctgagg gcttggtaga
    47461 ggtcgataca gctggttggg ctgaaggctg ggaaaaactc agtggccgaa tcaaggaagg
    47521 ctttgaaatg attgcaaaag aaatggaaga tcaaggtgga ggtaacgccc ttgttgtcag
    47581 ccatggaatg actattggaa ccattgttta tctgattaat ggcatgcatc cgcatggtct
    47641 agataatggt agcgtgacga ttcttgaata tgaggacggt cagtttaggg ttgaagttgt
    47701 cggtgaccgt agttaccgag agctaggacg tgagaagatg gaagaaggct ctatttaatc
    47761 agtctagact tgcttgccat gagctaggga tttgataaga atatcaagat aagaaaaaac
    47821 agccgagggt actcctttcg gctgtttttg atgtggaaaa ctaaagtgta atgctattgc
    47881 ttttagagat tttcataaac aagagcaagg aacctactgt tagaacagtc aggatagttg
    47941 acaaggctgc ggctacaccg taatttcctc tgagaacctc tgtataaata gctacagtca
    48001 ttgttcttgt tttgacattg tagaggagga tagaagtaga gagttttgaa atcattatga
    48061 cctaagataa gatggctcca gaaatgatac cagatagcat cattggagtt gtaatcttag
    48121 caaaggtatt gagacgacta cttcctaagc tttcagcagc ttcttcaata cttggtgcta
    48181 tttgttgtaa gctagcaaca gatgagcgaa tagtataagg taatcttctg acagatagag
    48241 acataatcaa gatgaaagca gtccctgtaa tcataagaaa tccacttcca aatagaccag
    48301 tattgaagga agaaatgaag gcaatcccta gaacggttcc tggtacaata taaggtacca
    48361 tactgaggct gtcaattaag tttgtaaaca aattccgttt tctaacggct aggtaggaga
    48421 taaatgtcgc aaatagaaca actagaacta aggcaatcaa agggatacga atggtattga
    48481 aaatagcaga tcccatacga ttgaaagcta ccttgtaact gtttggagaa taacctttaa
    48541 cagataccat acctgatgtt tttaggaaag aggtataaat taagtagatt tgaggtaaaa
    48601 cagagataaa gataattccg tagactgttg cataaatggc agctattttt ccttttgtag
    48661 tttttttagg ctcaattgga tggagcagat tcatgctgaa actgtagcgg tttgcaatgt
    48721 gtttttggat aaggaaaatt gccaagacaa tgataatcgc cataattgca aaagcagaat
    48781 ttcctccaac ctcgctaata aattgggtat aaatcaggac agggaaggtc cgatatcctt
    48841 cgccaatcaa cataggcgtt ccaaagtctg agaatgctct cataaataca agcaaggagc
    48901 tgctagtaag gttggaacta ggagaggtaa aacaaccgtt acgataggtt taaatccgaa
    48961 ggaccccatg ctttcagctg cttcaagtag agaattgtca atactgttca ttgttccagc
    49021 aacatataga aataccagtg ggaatagttg cagtgtaaag acaagtacaa ttcctttgaa
    49081 tccataaata tcgatagctg gaagatgaag ggcatttgtc aaaaatttag tgatgacccc
    49141 atttcgtcct agcaagagaa cccaggagta ggctcctacg aaaggagctg acatggaagc
    49201 aatgataatc aatatttgta gaaatttctt ccccttgaag tcatacatag agaagagata
    49261 agctaatagg gttcctacaa ctaaggaagt gacagtagcg gtaatggaaa ccttgaaact
    49321 gttgactagt gtctcagagt agtagacttt actaaagaaa gtgacaaaat tagctagtga
    49381 gaattgtcct tcatgtataa gtgcttgctt gagcacggta acgataggat aaacgagaaa
    49441 gacaagatag gtaagaaaga tgaagaaaga ggaggttgtc caaatattta gttttttaca
    49501 ttccatggtt gactcctttt atcaggtttt gggaaccatc tgcagaaaag atgtttaatt
    49561 tttgcgtatt gattcgtaga cgaatacgat tgcctttttg tagttcttct tcaaaagttg
    49621 attcttcact aacttgaatt tttgaggcaa aacctgtctc aatgaaatac tccgtattta
    49681 gtccaagata gacgctatcg ctaatagttc cttcaatatc tccagattca tctttgataa
    49741 actcttcggg acgaatgctt acatgaatag cttgctcctc aacctgatca agagctggca
    49801 ttcgaagggc atagccatct gaaaagacga tataagcgcc gtcgctccgt ttttcaagat
    49861 tagtagggat aatatttgtg cgtccgataa aggttgccac aaactcatta gctggtttat
    49921 gatagagttc ttttggtcgg ccgatttgtt ggatcacccc atctttcata acagcaattt
    49981 ggtctgaaat agccatggct tcttcttggt cgtgggttac ataaacagtt gtaattccca
    50041 cttcgtgttg gatttctcgg atggcttgac gcatatccaa gcgaagtttg gcctccagat
    50101 tactaagtgg ctcgtccatg aggagaacac ttggattaac cgctaaggcg catgccaagg
    50161 tgacacgttg ttgttgtcca ccactgagtt tatcgggctt tcaatccgca tattgagcaa
    50221 tttgcatgag ttcaagatac ttgttggtct gttgaatcaa ttcttctttt ggaaccttct
    50281 tttgcataag accaaaagca acgttgtctc ggacagtcaa atgtgggaaa atagcgtagt
    50341 tttggaaaac cagcccgata ttgcgtttgc tgggttccat attattgatt tttgtatcat
    50401 cgaagtaaaa ttctccatct ttgatactgt tgaaacctgc aatcatacga agaagggtcg
    50461 ttttcccaca tcctgaagct ccaagaaggg taaagagact tccttttgga attgtaatgt
    50521 tcaaattctc aataacaggg acatcgtggt agattttttt ggcgttaata atttcgatct
    50581 cactcatagt gaacctcttt tactgtttag attggatatc tgtaaagact tcgttgtatt
    50641 tcttaacgat atctgattta ttcttgatga cataatcata atcttcagtg agtgttttga
    50701 ttttgtcaat tggtttcatg ttttcgcttg ttttagcatt tttacgaaca ggacggttag
    50761 tagtggttgt accaagtgta tcttgtactt cttgagagat aataaaatcg ataaatttct
    50821 tggcattttc catattttta gcttttttaa cgatagcagc actagcaggt aggaagacgg
    50881 ttccttcttt tggatagact actttaatgt tagctccgtc atttaagagt ttaactgctg
    50941 gatcctcata agagagacca acagccattt ctccatcaac gactgcttta tagacaccag
    51001 atgaacttga accgatttta tagtgtattg aaactagaat agtacacctc tacttctaaa
    51061 acattgttag aaatcgattt gactgtcctg attaatttgt cctgttctta tttcatttta
    51121 ctataccatc aataagtgtg aaaagatctt ttacataaga ccaagcctta tcatctttgt
    51181 aaccaccttg agcttgtagc atatttgtta attgagcaaa ggcgctagaa gagtttgctg
    51241 ggtcagcagt tgcgattttt ccttttagtt caggtttgag aaggtcgcta tatccttcga
    51301 tgttcatgcc tttagttaaa tcagggtgga cgattaaaac actaccatct agtgtataag
    51361 gagtagagaa gccagttgtg ttttgatatt ctttgataac attatcattt tcttttgaaa
    51421 tatagttttc aaagagttct ccgtgggtag catattgtgt ataagaacca ccaaagataa
    51481 catcagctac aggaacttct ttttctgact ctagtttttt gaaaagttct ccagtaccag
    51541 cttgaatcag ttctattttg ataccatatt tttcttcaaa ggcaggaata gttgctccaa
    51601 ttaagccttc tgagtttggt gaataaacga ctagcgaacc accgtctcct ttatcagatg
    51661 aactgtcatc ggcagattca ttagaagaac aagcagcata atacatccat ttctttttca
    51721 tgatggatat ctccgttgtg ttatttaagt ttattttaaa acaatgtaag cgtttttaaa
    51781 acctacaatt ctattctata gtgtattgaa tctataacag tacactttga ctgctaaaat
    51841 atttctataa attaatttga ctttcctgat agagatgttc acatcttatt tcaattcact
    51901 atattagagt aaaattctct acaaaaagaa gaatagccta tttgactatt cttccgagtg
    51961 atttcaattt ctttggggaa atatggagat actttttaaa tactttggca aaatatttat
    52021 agtctgaaaa tccaacttgg tcagagatag cgcttaaagg ggagttggga gattcagcca
    52081 tcttatctat agcttgtttc aggcgatatt gtaagatata ttcatttaga gtcatgggga
    52141 agtcttcttt gataacctta tatagatgct tgttatctgc aaatagctag agcatttcaa
    52201 ggaaataaac tagaaataac aattaatatg gtggttcaga aatacctttt gataatcaat
    52261 aagatcttca ggatgaagtg cgttgattcc atccatttca tatttccgat ttaataaacg
    52321 atatttgttt tcaccaaatt gatgaaaagg gagtagttga acttggtcga tatttaatga
    52381 gttaaataga gtagcgaatt tttctgcatc ctctaaacta ttgttaaaat taggaataac
    52441 tgggattctt aaaacgatag ttttattttg agaaaaagca taatgaatgt ttttaataat
    52501 catttgatta aaaaccccag tcactttttt atgttttata gaattataat gttttaggtc
    52561 tgtgtagata aaatccacat attgaattaa atcaataaat ttttcatgat caacaaaggc
    52621 agtagtttca atggcagtgt gtatgtgatg ttctttagct gattttaaga tggctttagc
    52681 aaattcaaac tgagcaaata tttcacctcc tgataaagtt aaacctccac cggattcttc
    52741 gtaaaattct ttgtctttta atacctctgt aataatttct tctacagtct tttcttcacc
    52801 gactaaggtg aatttctctc gttgagcatc tttcattttt tcaggtttca ttctttgaga
    52861 ttcaggatta gaacaccatg gacagcgcag aggacatcct tttaaaaaaa cagttgtacg
    52921 aatacccggg ccgtcatgaa ttgaaaagtg ttgaatatta aaaataattc ctttagatat
    52981 ttccataaga gttcctcctc ttcataagtc tatcctatca caaaaacgaa agaaaaacaa
    53041 ttacgaacga aagtttaatt tgttgttttt tgctttttat tttggtagaa taaaacggag
    53101 gtgtaaaatg aaaagattgg aacaaattat taaattagta tcagaatatg aaaagatcga
    53161 cgttaataca ttatcggaaa aattaaatgt atcgaaagta acgattagaa aagatttaga
    53221 taaattagag tcaaaaggtt tattacacag agagcatgga tatgctgtat taaatagtgg
    53281 agatgactta aatgtacgtt tgtcaattaa ctatgaaatt aagagaaaaa ttgttcagga
    53341 agcagtaaaa ttggtgtcag ataatgaaac aataatgata gaatctggat cgacctgtgc
    53401 tttacttgct gaggaaattt gcaagcaaaa aagaaatgtt acgattgtaa caaattcatt
    53461 ttttatagca aattttgtga gagcttatga ttcatgtcgt attattgttc ttggtggaga
    53521 gtttcagaag gattcacagg ttactgtggg acctttatta aaagaaatga tacagacttt
    53581 tcatgtgcat caagcttttg ttgggacaga tggttacgat aaagagatgg gctttacagg
    53641 aaaagattta atgcgcagtg aggtagttca atatatttca gcagcgtcgg ataaagtcat
    53701 tgtactaact gactcaagta aatttgataa aaggggtaca gtaagaagat ttgctttaag
    53761 tcaagtctat gaagtaataa cagacgaaaa actttctaaa caaaatatag ctacattaga
    53821 aaatgctggg ataatggtta aggtagtttc gtaagaggtt aaatgtatga atcaagatag
    53881 gaataaactg ctctctaaaa ttgcttatct gtattatatt gaaaacttaa atcagtcaca
    53941 aatagcagca aaattaggaa tttatagaac ctctattagt agaatgttaa cagaagcaag
    54001 gaatgcagga attgttaaaa ttgaaataga gaattttgat accaatatgt ttaagttgga
    54061 aaattatgta aaagaaaaat atggtctgga aagtttagaa attattccaa atgaatttga
    54121 tgataatcca acaattttat ctgaaagaat ttctcaagtt gcagcaggtg tccttaggaa
    54181 tctaattgat gataatatga aaattggctt ttcttggggg aaaagtttaa gtaatttagt
    54241 agatttaatt cacagtaaaa gtgtccgaaa tgttcacttc tatcctctag caggtggtcc
    54301 tagtcacata cacgctaaat accatgtgaa tacactgatt tatgaaatgt ctagaaaatt
    54361 tcatggagag tgtacattta tgaatgcaac gattgtgcaa gaaaataaat tgttagcaga
    54421 tggtattttg caatcaagat attttgaaaa tttgaaaaat agttggaaag atttagatat
    54481 agctgtagtc ggaattggtg attttagcaa taaagggaaa catcaatggt tagacatgct
    54541 tacagaggat gactttaaag aattgaccaa agttaaaact gtaggagaaa tttgttgtcg
    54601 attttttgat tcaaaaggta aagaagtcta tgaaaactta caggaaagaa cgatagccat
    54661 ctctttggaa gatttaaaaa atattcctca aagtttagct gttgcttacg gtgatacgaa
    54721 agtatcttcg attctttctg tcttgcgtgc taatttagta aatcatttga ttacagataa
    54781 aaatacaatt ttaaaagttt tggaagaaga tggtgatttg acttttagag agattctagg
    54841 tgagtgaaaa tgatagactg atcagtttat cgttttttct ttttagtcga ttgcacattt
    54901 gtgcttatat aaacaaaaat agtttatctg ttgtttttgg attgacaact ttattatgta
    54961 gttgtattct atagttacaa aagaaaattt taaaatttca aatgaaaaaa gctttttaca
    55021 tagtgaaatg aggaggaatt tatggaaatt attgttccag atcaaattat catgggttta
    55081 attttatatg ctggcgatgc gaaacaacat atttataaag cattagatta cataaaaaat
    55141 ggtacatgtg aacggtgtga agaagaaatc cagttagctg atgccgcctt attagaagcc
    55201 cataatctac aaacaaaatt cttggcacaa gaagcgtctg gtacaaagac agaaattaca
    55261 gctctctttg ttcattcaca agatcatctc atgactagca tgacggagat taatttaatc
    55321 aaagaaatta ttagtttgag aaaagaactt cataaaaaat aatactagag tattatcatt
    55381 gttattaaca tagaggagga aaacataatg gtgaagattg gtttgttttg tgcagcaggt
    55441 ttttctactg gtatgcttgt aaataatatg aaaattgcag cgcaatctag tggagttgag
    55501 gcagaaatag aggcgttttc tcagtctaaa ttagcggatt atgcgccaaa tatagatgtt
    55561 gcactattgg gtccacaagt tgcttataca ttagataaat caaaagaaat ttgtgataag
    55621 tgtgatgttc cgatagctgt tattccgatg atggactatg gtatgttaga tgggaaaaaa
    55681 gtattagatt tggccctatc tttgattagt gggtaagaaa aggagattta ttatgtcaaa
    55741 gatggatgtt cagaaaatca ttgcaccgat gatgaagttt gtgaatatgc gtggcattat
    55801 agctctaaaa gatgggatgt tagcaatttt gccattgaca gtagttggca gtttgttctt
    55861 gattatggga caattgccgt tcgaaggatt aaataagagc attgctagtg tttttggagc
    55921 taattggaca gagccgttta tgcaagtata ttcaggaact tttgctatta tgggtctaat
    55981 ttcttgtttt tcaattgcct attcttatgc taagaatagc ggagtagagg ctttaccagc
    56041 tggagttcta tctgtatctg cattctttat tttgctaaga tcatcttata tccctaaaca
    56101 aggtgaggcg attggggacg ctattagtaa agtttggttt ggaggccaag gaattatcgg
    56161 tgctatcatt ataggtttgg tagtaggaag tatttatacc ttctttataa agagaaaaat
    56221 tgttattaag atgccagaac aagttccaca agctattgcc aaacagtttg aagcaatgat
    56281 tccagcattt gtaattttct tatcttctat gattgtatat attttagcga agtcattgac
    56341 taatggcgga acattcatag aaatgattta ttctgctatt caagttccgt tgcaaggttt
    56401 aactggatct ttgtatggtg ctattggaat tgcattcttt atatcatttt tgtggtggtt
    56461 tggtgttcat gggcaatcgg tagtaaatgg agtagtgaca gctctgcttt tatctaatct
    56521 tgatgctaat aaagctatgt tagcctctgg taatctatca ttagaaaatg gtgcacatat
    56581 tgttactcaa caatttttag attcattttt aattctatca ggttcaggga ttacgtttgg
    56641 tcttgtagtt gccatgcttt ttgcagcaaa atcaaaacaa taccaagcct taggaaaagt
    56701 tgcagctttt ccagcaatat ttaacgtaaa tgagccagtt gtatttggat ttccgattgt
    56761 catgaatcca gttatgtttg tacctttcat tcttgttcct gtacttgcag ctgtgatagt
    56821 atatggagct attgcaacag gtttcatgca accattctca ggggtaacat tgccttggag
    56881 tacaccagct attctatcag gatttttggt gggtggatgg caaggtgttg tgactcagtt
    56941 attagtattg gcgatgtcta caatggttta ctttccattc tttaagatac aagatcgttt
    57001 agcttgccaa aatgaaatca aacaatctta gaggtatttg tgtgttactg ttaaactcac
    57061 acatttgtgc taaaaattag agagttaaaa tttttctagt taaaagcttg aaaatttcta
    57121 taaaaatcgg tattatattt tcgaaagaaa taaaaatatt ttcgaaagaa aggtgcttac
    57181 gatggtaaat acagaagtag caagaacaac aatcaagaca gaatattttg gcagccttac
    57241 tgaaaggatg aacaaatatc gagaagatgt tttaaataaa aaaccttata ttgatgctga
    57301 gagagcagtt ctagcaacac gcgcctatga acgatacaag gaacaaccta atgtcctaaa
    57361 acgtgcatat atgctgaaag aaattttgga aaatatgtct atctatattg aagaagaatc
    57421 tatgattgcg ggaaatcaag cttcttccaa taaagatgct cctatttttc cggaatatac
    57481 gctagaattt gttctcaatg agttggatct ttttgaaaag cgtgatggag atgttttcta
    57541 tattacagaa gaaacaaaag aacaacttag aagtattgct ccgttttggg aaaataataa
    57601 tttacgtgct agagctggtg ccttattacc tgaagaagtg tctgtttata tggaaacagg
    57661 attcttcggt atggaaggta agatgaattc tggagatgct cacttagcag ttaactatca
    57721 gaaacttttg caatttggtt taagaggttt tgaagagcgg gctcgtaaag cgaaggtagc
    57781 tctagattta acagatccag caagtattga taaatatcat ttttacgact ctatatttat
    57841 cgtaatcgat gctattaaag tatatgcaaa gcgctttgtt gctcttgcta aaagtttagc
    57901 cgaaaatgca aatcctaaac gtaagaaaga attacttgag attgcagata tttgctctag
    57961 agtcccatat gaaccggcaa ctacttttgc agaagctatt caatcagttt ggtttattca
    58021 atgtatttta caaattgaat ctaatggcca ctctctttca tatggccgtt ttgatcaata
    58081 tatgtatcca tatatgaagg ctgatttaga aagtggtaaa gaaacagaag atagcattgt
    58141 tgaacgtctg acaaatcttt ggattaagac aattacaatt aataaggttc gcagtcaatc
    58201 acatacattt tcttcagcag gaagtccttt atatcaaaat gttacaattg gtggacagac
    58261 tcgagataag aaggatgctg ttaacccatt atcttatttg gtattaaaat cagttgcaca
    58321 aacccatcta ccgcaaccta atctaactgt acgttaccat gcaggtttag atgctcgttt
    58381 catgaatgag tgtattgaag tgatgaaact tggttttggt atgcctgcat ttaataatga
    58441 tgagattatt attccttctt ttattgcaaa aggagtattg gaagatgatg cttatgatta
    58501 cagtgccatt ggatgtgttg aaacggcagt tccagggaaa tggggctatc gttgcacagg
    58561 tatgagttat atgaacttcc ctaaggttct acttatcacg atgaatgatg gaattgatcc
    58621 ggcttcgggt aaacggtttg caccaagctt tggtcatttt aaggatatga agaacttttc
    58681 tgaattagaa aatgcttggg ataaaacact aagatatttg acacgaatga gtgttattgt
    58741 tgaaaattct attgatttat cattggaacg agaagttcct gatattctat gttcagcatt
    58801 gactgatgat tgtattggtc gtggaaaaca ccttaaagaa ggtggagcag tatatgatta
    58861 tatatcagga ttgcaagttg gaattgcaaa tttgtcggat tcattagctg caattaaaaa
    58921 attggtgttt gaggaagaac gtataagccc aagtcagctt tggcatgcac tggaaacaga
    58981 ttatgccgga gaagaaggta aggtcattca agaaatgttg attcatgatg cacctaagta
    59041 tggtaatgat gatgattatg ctgacaaatt ggttactgct gcttatgaca tttatgttga
    59101 tgaaattgct aaatatccta atacacgtta tggaagaggt ccaattggag gaattcgtta
    59161 ttcaggaaca tcttctatct cagccaacgt agggcaggga cgtggaacat tagcaactcc
    59221 agatggacgc aacgcgggta caccgttagc agagggttgt tcaccatcac ataatatgga
    59281 tcaacacggc cctacatctg ttttaaaatc tgtttcaaaa ttaccaacag atgaaatcgt
    59341 aggtggggtt ctcttaaatc agaaagtaaa tcctcaaacg ttagccaaag aagaagataa
    59401 attaaaacta attgctttgt tacgaacatt ctttaatcgt ttacatgggt accatattca
    59461 atacaatgtt gtttccagag agacgctgat tgacgctcag aaacatcctg aaaaacacag
    59521 agacttaatt gttcgtgttg caggatactc tgcattcttc aatgttcttt ctaaggcaac
    59581 ccaagatgac attataggac gtactgagca tactttgtaa aataaagagg ttctttttat
    59641 ggaatttatg cttgacacat taaatttaga tgagattaaa aagtggtctg aaattttgcc
    59701 gctagctggg gtaacttcaa atcccactat tgcaaaaaga agagagggtt ctattaattt
    59761 ttttgaacga atcaaagatg taagagaatt gattggctct acaccctcta ttcatgttca
    59821 ggtgatttct caagattttg aaggcatctt aaaggatgct cataaaattc gaagacaagc
    59881 aggagatgat atatttatca aagtacctgt tactccagct ggattacgtg caataaaggc
    59941 gctaaaaaaa gagggctacc atatcactgc aacagctatt tatacagtta ttcagggatt
    60001 attagctatc gaagcaggag cggattacct agctccatat tataatagaa tggaaaatct
    60061 gaacattgat tcaaattctg tcattcgtca attagctctt gctattgata gacagaactc
    60121 tcctagtaag attttagctg catcctttaa aaatgtagca caagtaaata atgctttagc
    60181 tgcaggtgcg catgctgtta cagcaggagc ggatgttttt gaatcagctt tcgccatgcc
    60241 atctatccaa aaggcggttg atgatttttc tgacgattgg tttgttattc aaaatagtcg
    60301 ttccatttag atagagagga aatacatatg agaatttttg ctagtccttc tagatatatt
    60361 cagggggaaa atgccttgtt tgaaaatgcc aaatcaattt tggatttggg aaattgccct
    60421 attctattat gcgatcagtt ggtttatgat attgttggaa aacgatttga agattaccta
    60481 cataggtatg gtttccatat tgttctggcg ctatttaatg gtgaagcttc tgacaatgaa
    60541 atcaatcgag ttgttgcctt ggctgagaaa gaaaattgtg atagtattat cggtcttggt
    60601 gggggaaaga cgattgatag cgcaaaagct attgcagatt tgattgaaaa gcctgttatt
    60661 attgctccaa caattgcatc gaccgacgca cctgtatctg ctttatctgt tatttataca
    60721 gatgaaggtg catttgatca ttatctattt tattctaaaa atccagattt agttttggtt
    60781 gatacaaaag ttatttcaca agcccctaag cgtttattag cgtctggtat tgcagatggt
    60841 ttagcaactt gggttgaggc gcgtgcggtt atgcaggcaa atggaaaaac tatgttggga
    60901 caacagcaaa cattggctgg agttgcaatt gcgaagaaat gtgaagaaac gctgtttgca
    60961 gatggtttac aggctatggc agcttgtgaa gctaaagtgg tgacaccagc attagaaaat
    61021 attgttgaag ctaatacttt attgagtggt ctaggttttg aaagtggagg attagctgcg
    61081 gcgcatgcaa ttcataatgg ttttactgca ttgacaggtg acattcatca tttaacacat
    61141 ggtgaaaaag tagcttatgg aactttagta caactattat tggaaaatag acctaaagaa
    61201 gaacttgata agtatattga gttttacaaa aaaattggta tgccaacaac tctaaaagaa
    61261 atgcatttgg atcaagttgg atatgatgat ttaataaaag ttggtaaaca agcaactatg
    61321 gagggtgaga caattcatca gatgccgttt aagatttcgc cttcagatgt tgctcaagct
    61381 attatcgctg tagatgccta tgtaaattca aaataaacaa taaggactac tgttttccaa
    61441 atggtagtct tttattgatc cctgtattga attctataga agattgaaat aggatgagaa
    61501 caaatcgatt gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta
    61561 tttcagattc agtctactat atgttcttca taaatcaaaa agcgacatag gttgtcggca
    61621 atcaaaaagc gacataggtt gtcggctatt tattgtgaat acattaatta gcattccagt
    61681 tttatcttcg gtctaaaata agtattttgt gctatacgag ataagcttct tgacttactc
    61741 cttgatttac tgcataacaa tgggataaaa agtgggagat agagcaattc atagtcatca
    61801 aaattaatga gatacagtat acagtttttc ctttaaacac atttcaaatt ccctcaaaaa
    61861 tggtataata gtaacatcac aaaattggag agagaccatg agtttttaca atcataaaga
    61921 aattgagcct aagtggcagg gctactgggc agaacatcat acatttaaga caggaacaga
    61981 tgcatcaaaa cctaagtttt atgcgcttga tatgttccct tatccgtctg gagctggtct
    62041 gcacgtagga cacccagaag gttatactgc aaccgatatc ctcagtcgtt acaaacgtgc
    62101 gcaaggctac aatgtccttc acccaatggg ttgggatgct tttggtttgc ctgcagagca
    62161 atacgctatg gatactggta atgacccagc agaatttaca gcggaaaaca ttgccaactt
    62221 caaacgtcaa attaatgcgc ttggattttc ttatgactgg gatcgtgaag tcaacacaac
    62281 agatccaaac tactacaagt ggactcaatg gattttcacc aagctttacg aaaaaggctt
    62341 ggcctatgaa gctgaagtgc cagtaaactg ggttgaggaa ttgggaactg ccattgccaa
    62401 tgaagaagtg cttcctgacg gaacttctga gcgtggaggc tatccagttg tccgcaaacc
    62461 aatgcgccaa tggatgctca aaatcacggc ttacgcagag cgcttgctca atgacttaga
    62521 tgaactagat tggtcagagt ctatcaagga tatgcaacgc aactggattg gtaaatcaac
    62581 tggtgccaat gtaactttca aagtaaaagg aacagacaag gaatttacag tctttactac
    62641 tcgtccggac acacttttcg gtgcgacttt cactgtcttg gctcctgaac atgaattagt
    62701 agacgctatc acaagttcag agcaagcaga agctgtagca gactataaac accaagccag
    62761 ccttaagtct gacttggctc gtacagacct tgctaaagaa aaaacagggg tttggactgg
    62821 tgcttatgcc atcaaccctg tcaatggtaa ggaaatgcca atctggattg cagactatgt
    62881 ccttgctagt tatggaacag gtgcggttat ggctgtgcct gcccacgacc aacgtgactg
    62941 ggaatttgcc aaacaatttg accttccaat cgtcgaagta cttgaaggtg gaaatgtcga
    63001 agaagctgcc tacacagagg atggcctgca tgtcaattca gacttcctag atggactcaa
    63061 caaagaagac gctattgcca agattgtggc ttggttggaa gaaaaaggct gtggtcagga
    63121 gaaggttacc taccgtctcc gcgactggct ctttagccgt caacgttact ggggtgagcc
    63181 aattccaatc attcattggg aagatggaac ttcaacagct gttcctgaaa ctgaattgcc
    63241 gcttgtcttg cctgtaacca aggatatccg tccttcaggt actggtgaaa gtccactagc
    63301 taacttgaca gattggcttg aagtgactcg tgaagatggt gtcaaaggtc gtcgtgaaac
    63361 caacactatg ccacaatggg ctggttcaag ctggtactac ctccgctata ttgatccaca
    63421 caatactgag aagttggctg atgaggacct cctcaaacaa tggttgccag tagatatcta
    63481 cgtgggtggt gcagagcatg ctgttcttca cttgctttac gctcgtttct ggcacaaatt
    63541 cctctatgac ctcggtgttg ttccgactaa ggaaccattc caaaaactct ttaaccaagg
    63601 gatgattttg ggaacaagct accgtgacca ccgtggtgct cttgtggcaa ccgacaaggt
    63661 tgaaaaacgt gatggttcct tcttccatgt agaaacaggg gaagagttgg agcaagcgcc
    63721 agccaagatg tctaaatcgc tcaagaacgt tgttaaccca gacgatgtgg tggaacaata
    63781 cggtgccgat acccttcgtg tttatgaaat gtttatggga ccactcgatg cttcgattgc
    63841 ttggtcagaa gaaggtttgg aaggaagccg taagttcctt gaccgagttt accgtttgat
    63901 tacaagtaaa gaaatccttg cggaaaacaa tggtgctctt gacaaggttt acaacgaaac
    63961 agtcaaagct gttactgagc aaattgagtc tctcaaattc aacacagcta ttgcccaact
    64021 tatggtcttt gtcaatgctg ctaacaagga agataagctt tatgttgact atgccaaagg
    64081 ctttattcaa ttgattgcac catttgcacc tcacttggca gaagaactct ggcaaacagt
    64141 cgcagaaaca ggtgagtcaa tctcttatgt agcttggcca acttgggacg aaagtaaact
    64201 ggttgaagac gaaatcgaaa tcgttgtcca aatcaaaggt aaagtccgtg ccaaactcat
    64261 ggtcgctaaa gacctatcac gtgaagaatt gcaagaaatt gctctagcgg atgaaaaagt
    64321 caaagcagaa attgacggta aggaaatcgt gaaagtgatt agtgtaccaa ataaattggt
    64381 taatattgtt gtaaaataac caatttattt gctgatttcc aacctcaaac agtttcccaa
    64441 actgtttgag ccaactaaac tcgttaatat cgttgtgaaa taaggtagga atccttcaga
    64501 gtagaatctg gaggattttt tgaatcttct tatgaaagta tggtatacta tgggcaacta
    64561 taaagtttga aaagtgaaaa aaggagaaag ctatgccagt aaatgaatat ggtcaaatga
    64621 ttggggagtc aatggaaggt tatacaccag gtgaactgcc ttctattgat ttcttagaag
    64681 ggcgttatgc taggatagag gctctttcag tggaaaagca tgcggaggat ttgctagctg
    64741 tttatgggcc tgatacgcct caggagatgt ggacctacct ttttcaggag ccagtagcag
    64801 atatggggga gctggttagc cttttacatc agatgttggc tcgtaaggac cgtttttact
    64861 atgcaatcat agacaaggcg actggtaagg ctttgggatc tttttctctc atgcgcattg
    64921 accagaataa ccgagtaata gaagtcggag cagtcacttt ttctccagag ctaaggggta
    64981 cacggatagg aactgaagct cagtatctcc tagctcgcta tgtttttgag gagctaaact
    65041 atcgtcgcta cgagtggaaa tgcgatgcct taaatctgcc atccagacga gctgcggagc
    65101 gtttgagctt tatttatgaa ggaaccttcc gtcaggcagt ggtttataag ggacgtacga
    65161 gagatacgga ttggttgtct atgattgata aggactggcc tcaagtcaaa gatcgtttgg
    65221 aaacatggtt gcgtcctgaa aattttgata aaaatggaca gcagtacaag agcttgagag
    65281 aactttaaga ggtgttgaca tgattactat taaaaagcaa gaaattgtca agctagagga
    65341 tgttttacat ctctatcagg ctgtcggttg gacaaattat acccatcaac cagagatgct
    65401 ggagcaggcc ttatctcatt cattagtaat ttatctggca cttgatggtg atgctgtggt
    65461 gggcttgatt cgtttggttg gagatggatt ctcatcagta ttggttcagg atttaatcgt
    65521 tttaccaatc tatcagcgtc aaggaattgg tagtgccttg atgaaagagg ctttagagga
    65581 ttacaaagat gcctatcaag tccagctggt gacagaagag acagaaagaa ccttgggctt
    65641 ctatcgttct atgggctttg aaatcttatc cacctataat tgtataggga tgacttggat
    65701 gaatcgtaaa aaataacaaa acttgttttt tcttaagcaa aatttaagga tggtctagta
    65761 ttatatagtc attaaataaa gacctcctaa ctttatttaa taaaatccta aacttttttc
    65821 atcacaatct cctaatgaag ccacccaatc aggtggcttt tttgcgtggt gaggtgctgg
    65881 tgatagaaat tttttgcaaa atagtaaaat tttagaaaag ttaagctagt tttaagtttc
    65941 gtcttgtatc atgtagttat taaataaaga cctcctaact ttatttaata aaatcctaaa
    66001 cttttctttt tcataataat ctcccttaac tccacccaat caggtggagt tttttagctc
    66061 tatttcaggc ttttggggac tattctaaaa ataatttttc gatatttttc ggtatttttc
    66121 ggattttggt cggggaattg gcggggactt ttttagcgaa tataactaag aaataggtct
    66181 gtggtcgctt cagctagttc aaactcaatt tgattgtaag tgactgttaa ttgaagaact
    66241 ggaactactg taataatgat tttgcttgtc tagtagtggc gtattaaatg agaagtgaca
    66301 tgtaagattg tctcttcgtt tacgaaatca aaatttctat gaaattgata gaatccctaa
    66361 cgttctctta atcttaaccg tcttgtcgta cagcggttga agaaaatgta aacctttgac
    66421 aaaattcgtg aactatgaga taataaaaag gaattgagta ctagttctat atcataggct
    66481 agaaaagacc ccaagctcac gaccaaataa gcttggggtc ttttttgaca ctatttgtcc
    66541 ttgtttagcc atttatcgac tatacgaaga acgacaccga ccacaattgg tccgatgata
    66601 gttttgagta ctaattccat catgggctat ctcacctcct ttcgtaggcg gtgtagcagt
    66661 gtcgtagaat attataccac ataagtgcta aacttaggag tcacccaatc aggtggcttt
    66721 tttgtttgtg gcttggtttt ttgatataat agagccatga gtagaatttt agataatgag
    66781 ataatggggg atgaggagtt agtagaacgc acgctccgtc ctcagtattt acgtgaatat
    66841 atcggacagg ataaggtcaa ggaccagcta caaatcttta ttgaagctgc caaaatgcgg
    66901 gatgaagcgc tggatcatgt gctcttattt gggcctccag gtctcgggaa aacgaccatg
    66961 gcctttgtta ttgccaacga actgggagtc aatcttaagc agacgtcggg tccagtcatt
    67021 gaaaaagccg gagatctggt agctattttg aatgagttag agcctgggga tgtacttttt
    67081 attgatgaga tccatcgttt gccaatgtca gtggaagagg tgctttatag tgctatggag
    67141 gacttctaca tagatattat gattggggct ggtgagggta gtcgtagtgt tcatttggag
    67201 ttaccacctt ttaccttgat tggtgcgacg actcgggctg gtatgctctc caatccgcta
    67261 cgggcacgtt ttgggattac aggccatatg gagtattatg cccatgctga cttgacagaa
    67321 attgtcgagc ggacggcaga tatttttgag atggaaatca ctcatgaggc agcatctgag
    67381 ttggccctac gtagtcgtgg gacccctcgt attgccaatc gtctcctcaa gcgcgtgcgc
    67441 gattttgccc agataatggg gaatggggta attgatgata ttattaccga taaggctttg
    67501 actatgctgg atgttgacca tgaaggtttg gactatgtgg atcaaaaaat ccttcgtacc
    67561 atgattgaga tgtacagtgg aggacctgtt ggtctaggaa ctctttctgt gaatatcgcc
    67621 gaagagcgtg agacagttga agatatgtat gagccttact tgattcaaaa aggttttatc
    67681 atgcggacac ggtctggacg ggtggcgact gctaaggcat atgagcactt aggttatgaa
    67741 tacagtgaaa aataagcaag aaatcttaga ggcttttaga gaaaatccag atatgatggc
    67801 cattctgacg atcatccgag accttggtct gaaagactcg tggttggcag caggttctgt
    67861 cagaaatttc atttggaatc ttttgtcaga caaatcccct tttgatcatg aaacagatat
    67921 agatgtgatt ttctttgatc cagatttttc ttatgaggaa accttattac tggagaaaaa
    67981 gctgcgagag gattttcctc agtaccagtg ggaattgaaa aatcaggtct atatgcatca
    68041 gcacagtcct cacactgctt cctataccag ttctcgtgat gctatgagta agtatccaga
    68101 acggtgtacg acagttggac tgcgcttgaa tgaagaatca gattttgaac tctatgcacc
    68161 ttatggtttg gaggatattt tgaattttca agttcgtcca actcctcatt tcttagaaaa
    68221 tgaagaccga atggaactct atcaaacacg tttatccaag aaaaattggc aggagaaatg
    68281 gaaaaatttg atttttaaaa atacttaagg aaactttaag ctagggagtg tacactaagt
    68341 tcataagtta agaagacctt aacttaaact cctaaaactt tttcataata atctccctat
    68401 aaaaataaag tcgcccaatc aggcggctta tttttttgaa aaatgggctt ggtgcctgag
    68461 aataaatagc ttagtgatag aagaaaatgg ggaaatatgg tataataaaa cgatagattt
    68521 ttgaatagga ataagatcat gtttggattt tttaagaaag ataaggctgt ggaagtagag
    68581 gttccgacac aggttcctgc tcatatcggc atcatcatgg atggcaatgg ccgttgggct
    68641 aaaaaacgta tgcaaccgcg agtttttgga cataaggcgg gcatggaagc attgcaaacc
    68701 gtgaccaagg cagccaacaa actgggcgtc aaggttatta cggtctatgc tttttctacg
    68761 gaaaactgga cccgtccaga tcaggaagtc aagtttatca tgaacttgcc agtagagttt
    68821 tatgataatt atgtcccgga actacatgcg aataatgtta agattcaaat gattggggag
    68881 acagaccgcc tgcctaagca aacctttgaa gctttaacca aggctgagga attgactaag
    68941 aacaacacag gattgattct taattttgct cttaactatg gtggacgtgc tgagattaca
    69001 caggcgctta agttgatttc ccaggatgtt ttagatgcca aaatcaatcc aggtgacatc
    69061 acagaggaat tgattggtaa ctatctcttt acccagcatt tgcctaagga cttacgagac
    69121 ccagacttga ttatccgtac tagtggagaa ttgcgtttga gcaatttcct tccatggcag
    69181 ggagcctata gtgagcttta ttttacggac accttatggc ctgattttga cgaagcggcc
    69241 ttgcaggaag ctattcttgc ctataatcgt cgtcatcgcc gatttggagg agtttaggag
    69301 gaaatatgac ccaggattta cagaaaagaa ccttgtttgc agggattgcc ctggctattt
    69361 tcctaccaat tttaatgatt gggggcctct tgcttcagat agcaatcgga atcatagcca
    69421 tgctagccat gcatgaactt ttgaagatga gaggtctaga gaccatgacg atggagggcc
    69481 tcttgaccct ctttgcaacc tttgcattga ccattccctt ggagaattac ctgacttttt
    69541 tgccagttga tgggaatgtg gttgcctata gtgttttgat ttcaatcatg ttaggaacga
    69601 ccgtttttag caagtcttat acgattgagg atgcggtttt ccctcttgct atgagcttct
    69661 acgtgggctt tggatttaat gctttactag atgctcgtgt tgcaggtttg gacaaggctc
    69721 tcttagcctt gtgtatcgtc tgggcgacag acagtggtgc ctatcttgtt gggatgaact
    69781 atgggaaacg aaagttagca ccaagggtat cgcctaataa aacccttgag ggtgccttgg
    69841 gtggtatttt aggagcaatt ttagtaacca ttatctttat gatagttgac agtacagttg
    69901 ctcttccata tggaatttac aagatgtcag tctttgctat tttctttagc attgctggac
    69961 aatttggtga tttactagaa agttcgatca aacgtcattt tggtgttaag gattctggga
    70021 aatttatccc tggacatggt ggtgttttgg atcgtttcga tagtatgttg cttgtatttc
    70081 caatcatgca cttatttgga ctcttttaat caaaagacgg aggaaacgct atgctcggaa
    70141 ttttaacctt tattctggtt ttcgggatta ttgtagtggt gcacgagttc gggcacttct
    70201 actttgccaa gaaatcaggg attttagtac gtgaatttgc catcggtatg ggacctaaaa
    70261 tttttgctca cattggcaag gatggaacgg cctataccat tcgaatcttg cctctgggtg
    70321 gctatgtccg catggccggt tggggtgatg atacaactga aatcaagaca ggaacgcctg
    70381 ttagtttgac acttgctgat gatggtaagg ttaaacgcat caatctctca ggtaaaaaat
    70441 tggatcaaac agccctccct atgcaggtga cccagtttga ttttgaagac aagctcttta
    70501 tcaaaggatt ggttctggaa gaagaaaaaa catttgcagt ggatcacgat gcaacggttg
    70561 tggaagcaga tggtactgag gttcggattg cacctttaga tgttcaatat caaaatgcga
    70621 ctatctgggg caaactgatt accaattttg caggtcctat gaacaatttt atcttaggtg
    70681 tcgttgtttt ttgggtttta atctttatgc agggtggtgt cagagatgtt gataccaatc
    70741 agttccatat catgccccaa ggtgccttgg ccaaggtagg agtaccagaa acggcacaaa
    70801 ttaccaagat tggctcacat gaggttagca actgggaaag cttgatccaa gctgtggaaa
    70861 cagaaaccaa agataagacg gcaccgactt tggatgtgac tatttctgaa aaggggagtg
    70921 acaaacaagt cactgttaca cccaaagata gtcaaggtcg ttaccttcta ggtgttcaac
    70981 cgggggttaa gtcagatttt ctatccatgt ttgtaggtgg ttttacaact gctgctgact
    71041 cagctctccg aattctctca gctctgaaaa atctgatttt ccaaccagat ttgaacaagt
    71101 tgggtggacc tgttgctatc tttaaggcaa gtagtgatgc tgctaaaaat ggaattgaaa
    71161 atatcttgta cttcttggca atgatttcca tcaatattgg gatttttaat cttattccga
    71221 ttccagcctt ggatggtggt aagattgtgc tcaatatcct agaagccatc cgccgcaaac
    71281 cattgaaaca agaaattgaa acctatgtca ccttggccgg agtggtcatc atggttgtct
    71341 tgatgattgc tgtgacttgg aatgacatta tgcgactctt ttttagataa tcgaggaata
    71401 ttatgaaaca aagtaaaatg cctatcccaa cgcttcgcga aatgccaagc gatgctcaag
    71461 ttatcagcca tgctcttatg ttgcgtgctg gttatgttcg ccaagtttca gcaggtgttt
    71521 attcttatct accacttgcc aatcgtgtga ttgaaaaagc taaaaacatc atgcgccaag
    71581 aattcgaaaa gattggtgct gttgagatgt tggctccagc ccttcttagt gcagaattgt
    71641 ggcgtgaatc aggtcgttac gaaacctatg gtgaagacct ttacaaacta aaaaaccgtg
    71701 aaaaatcaga ctttatctta ggtccaactc acgaagaaac ctttacagct attgtccgtg
    71761 attctgttaa atcttacaag caattgccac tcaaccttta tcaaattcag cccaagtatc
    71821 gtgatgaaaa acgcccacgt aatggacttc ttcgtacacg tgagtttatc atgaaggatg
    71881 cttatagttt ccacgctaac tatgatagtt tggatagtgt ttatgatgag tacaaagcag
    71941 cctatgagcg tatttttact cgtagtggtt tagacttcaa ggctattatt ggtgacggtg
    72001 gagccatggg tggtaaggat agccaagaat ttatggccat tacatctgct cgtacagacc
    72061 ttgaccgctg ggttgtcttg gacaagtcag ttgcctcatt tgacgaaatt cctgcagaag
    72121 tgcaagaaga aatcaaggca gaattgctca aatggatagt ctctggtgaa gataccattg
    72181 cttactcaag tgagtctagc tatgcagcta acttagaaat ggcaacaaac gagtacaaac
    72241 caagcaaccg tgttgtcgct gaagaagaag ttactcgtgt tgcaacgcca gatgttaaat
    72301 caatagatga agttgcagct ttcctcaatg ttccagaaga acaaacgatt aaaaccctct
    72361 tctacattgc agatggtgag cttgttgcag cccttctagt tggaaatgac caactcaacg
    72421 aagtcaagtt gaaaaaccac ttaggagcag atttctttga cgttgctagc gaagaagaag
    72481 tggcgaatgt tgttcaagca ggatttggtt cacttggacc agttggtttg ccagagaata
    72541 ttaaaattat tgcagatcgt aaggtgcaag atgttcgcaa tgcagttgtc ggtgctaacg
    72601 aagatggcta ccacttgact ggtgtgaacc caggccgtga ttttacttca gaatatgtgg
    72661 atatccgtga agttcgtgag ggtgaaattt ccccagatgg acaaggtgtc cttaattttg
    72721 cgcgtggtat tgagatcggt catattttca aactcggaac tcgctattca gcaagcatgg
    72781 gagcagatgt cttggatgaa aatggtcgtg ctgtgccaat catcatggga tgttacggta
    72841 tcggtgtcag ccgtcttctt tcagcagtga tggagcaaca cgctcgcctc tttgttaaca
    72901 aaacgccaaa aggtgaatac cgttacgctt ggggaatcaa tttccctaaa gaattggcac
    72961 catttgatgt gcatttgatt actgttaatg tcaaggatga agaagcgcaa gccttgacag
    73021 aaaaacttga agcaagcttg atgggagctg gttatgaagt cttgacagat gaccgtaacg
    73081 aacgtgtcgg tgttaaattt agcgatagtg acttgattgg tcttccaatc cgtatcactg
    73141 ttggtaaaaa agcggccgat ggcattgtag aagttaagat caaggcaact ggtgacacca
    73201 ttgaggttca tgcagataac gtgcttgaaa cgcttgaaat cctaagtaag aaataaaaac
    73261 tataatcaga agaaaaacaa ggaaaaaatg taactagttt ttaccttgtt ttttctgtat
    73321 aatgggagaa atgagtagat aaagaggtaa atgtatgcta agatttccaa aggattttgt
    73381 ctggggatcc tctacttctg gaccgcagac agaaggacgt gtagctggtg acggtaaggg
    73441 agacaatctc tgggattact ggttccaagt ggagccaaat cgttactata atgggattgg
    73501 ttcagataag acatcgactt tttatgaaaa ttgggagcgg gatattgagc ttttgttaga
    73561 gactggtcac acagcctttc ggacttctat tcagtggtca cggatttttc cacaaggctg
    73621 tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag gtctttgagg ctattaaggc
    73681 taaaggaatt cgtctgttag tcaatctcta tcattttgat ttaccttttg cccttcaaga
    73741 ggatggtgat ggttgggaaa ataaggcgac agtttcagcc tatgaagact atgctcgttt
    73801 ttgttttgag acttatggag atttagtgga tcaatggatt acctttaacg agcccatcgt
    73861 tcctgtagaa tttggttatt tttatgatgc ccattatcca cataaggtgg atgcagaggc
    73921 agctgttaag gtagcctatc atacacaatt ggccagcagc cgggctgtta aggcttgcca
    73981 tgaacttttg cctgattcca agattgggat tgtcctcaac ttgacaccgg cttatccacg
    74041 tagccagcat cctgctgatg tcaaggcagc tcgtattgcg gccctttttc aggcccaatc
    74101 tttcttagat ccatctgtct tggggactta tccacaggag ttggtagaaa tcttgcatga
    74161 acacggtctt ttacctgatg ctacagagga agagttggaa ctcattcgtg ataatacggt
    74221 ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt atggctcctc gatttgctaa
    74281 gcatccagag agtccactct taccagaaca tttttacgag cattatgtga tgcctggacg
    74341 taaaatcaat tctcaccgtg gttgggagat ttatgagcaa gggatttatg acatcgccca
    74401 aaatatcaag gaaaattatg gcaatattga gtggatgttg actgagaatg gtatgggtgt
    74461 tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa gatgattacc gtattgactt
    74521 tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa gatggtgcca actgtaaggg
    74581 ctacttgatt tggaccttta ttgactgctg gtcatggctc aacagctata aaaatcgcta
    74641 tggtttggtc gaattagact tggaaacgca agaacgtcgt ctgaagaaat caggccactg
    74701 gttcaaagaa ttaagcgata ataatggatt ttaaaaagga ctctgactga ttatcccaat
    74761 cggtcagagt ttttatgctt acaggagctt aatttgaact ataccaattt ttactcttga
    74821 caagtgaaag aaacaagtat atactgtttt tactgattct ataaaagatg aattagacta
    74881 taccaatttt aaggagaaag cacagcttgc ctgtgtcgta tatactatgt gtggaattgt
    74941 tggtgttgtt ggaaacacaa atgcaactga tattttgatt caagggcttg aaaagcttga
    75001 ataccgtggc tatgattctg cgggaatttt tgtcctagat ggtgctgata accatttggt
    75061 gaaggcggtt ggtcgtattg cagaattgtc tgccaagaca gctggtgttg agggaacaac
    75121 tggtatcgga catactcgtt gggctactca cggaaaacca actgaggaca atgctcaccc
    75181 acaccgctct gagacagaac gttttgtctt ggtgcataat ggggtgattg agaactatct
    75241 tgaaatcaag gaagaatacc ttgcaggtca ccacttcaag gggcagacag atactgaaat
    75301 agccgttcat ttgattggaa aatttgcgga agaagaaggg ctctcagttc ttgaagcctt
    75361 caaaaaagct cttcatatta tccgtggttc atatgccttt gccttgattg actctgaaaa
    75421 tccagatgtc atctatgtag cgaaaaacaa atctccactt ttgattggtc ttggggaagg
    75481 ctacaatatg gtctgctcag atgctatggc tatgattcgt gaaaccaacc aatacatgga
    75541 aattcatgac caagagttgg taatcgtcaa ggctgatagc gtggaagttc aagactatga
    75601 tggtaacagt cgtgaacgtg ctagctatac tgcggaactt gacttgtcag atatcggtaa
    75661 gggaacttat ccttactaca tgcttaagga aattgatgag caaccaactg ttatgcgtaa
    75721 actcattcaa gcctacacgg atgatgctgg tcaagtagtg attgatcctg ctatcattaa
    75781 ggctgttcaa gacgcagacc gcatctacat ccttgcagct ggaacatctt accatgcagg
    75841 atttgcttct aagaaaatgt tggaagaatt gacagataca ccagttgaac ttggaatctc
    75901 atctgagtgg ggctacggta tgccacttct cagcaagaaa ccactcttca tctttatcag
    75961 ccaatctggt gaaacagcgg atagtcgtca agttttggtc aaggctaatg aaatgggaat
    76021 tccaagctta acagtgacaa acgttccagg ttcaaccctc tcacgtgaag ccaactatac
    76081 catgctcctt cacgcaggtc ctgaaattgc cgtggcatca actaaagcct atacagcgca
    76141 aatcgcagcc cttgccttcc ttgcaaaagc agtcggagaa gcaaatggta atgctaaagc
    76201 gcaagccttt gacctggttc atgaattgtc aatcgtagct cagtctatcg aatcaactct
    76261 ttcagagaaa gaaaccattg aagccaaggt tcgtgaactt cttgaaacaa ctcgtaacgc
    76321 cttttacatc ggacgtggtc aagattacta cgtagccatg gaagcaagtc tcaaactcaa
    76381 agagatttct tatatccagt gtgaaggttt tgcggcagga gaactcaagc acggaaccat
    76441 tgccttgatt gaagaaggaa cgcctgtctt gtctctcttg tcagatccag ttcttgccaa
    76501 ccatactcgt ggaaatatcc aagaggtcgc agcccgtggt gccaaagtcc tcactatcgc
    76561 agaagagaat gtagccaaag ataccgacga tatcgtcctt acgaccgtac atccatacct
    76621 ctcaccaatt tcaatggtcg taccaacgca attagtcgct tactttgcaa ccctccaccg
    76681 tggcttcgat gtggacaaac cacgtaacct tgccaagtca gtaacggtag aataagctaa
    76741 aaaagtctag ttatctaggc ctttttcttg tgagcaaatt ggttgcttgt actcaagatt
    76801 cgtgttatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtaggtatg
    76861 gttactgact tcgtcagttc tatccacaac ctcaaaacac tgttttgagc agcctgcagc
    76921 tagcttccta gtttgctctt tgattttcat tgagtattag aataattttt caaattgaag
    76981 tacagagata gataaggaga atcacaatgg tagaattggg aatttcaaca tttggggaaa
    77041 taacggagct tgaagggact ggacaaactt acagtcatgc tgaacgcatt cgccagttgg
    77101 tggcagagat tgagctggct gacaaggttg gtttggatgt atatgggatt ggtgagcacc
    77161 atcgggcgga ttttgcagta tcagccccag agattgttct ggccgctggg gcagtcaata
    77221 ccaagaaaat ccgtttgacc agtgcagtca gcattctgtc aagcatggac ccgattcgtt
    77281 tgttccaaca gtatgccact atcgatgctt tgtcaaatgg acgagcggag attatggctg
    77341 gaaggggctc tttcacggaa tctttccctc tgtttggtta tgacttgaaa gactacgact
    77401 ctctttttga tgagaaatta gccttgcttc agttagtcaa tgaaaagacc aagttagact
    77461 ggcaaggtcg attgactcaa acgattgctg gtaaagaagt ttatcctcgt ccagttcagg
    77521 acaaattgcc cttgtggata gctacaggtg gtcatgtcga atcaacagtg aagattgctc
    77581 aggctggtct accgattgta tatgctatta ttggtggtaa tccacgttat tttaaaaagt
    77641 tgattcaggc ttatcgtgag attggaagcg aagcgggtca tgctgacaaa gacttgaaag
    77701 tgggagccca ttcttggggg tggattgcgg aagatggtga gcaggcggtg aaagattatt
    77761 tccatccgac taagcaagtg gtggatgcta tttccaaaga ccgtccgcac tggcaggaat
    77821 tgcgttatga gcaatatttg gagcaggtag ggccaaatgg cgccatgttt gttggcaatc
    77881 cagatcaggt ggccgaaaaa ttgattcgca tgatagagga tttaggattg gaccgcttca
    77941 tgcttcatct accgcttggt tctatgcctc atgaccaggt tctgagagct attgaactct
    78001 tcggaacaca agttgcaccc aaagtacgag cttattttgc tatgaaagag gcttaataaa
    78061 aaatcctaat caagtttatt aggacaacaa atattgtacg aaaattaatc ccccgagcta
    78121 taatgcttgg gggatttttc tataggaggg ctagtttagt tctctttttt attttttagt
    78181 aagaaaccga gaccaaggag cgcaaggagg ctgattcctg caaataggag tttgttttcg
    78241 tttttgattc ctgtatttgg aagttcagct tgtctatctg gggttgcagg tatatttttc
    78301 ttgctagagt tttctaccga ttcgttttga accgcttctt ttacagatga tgcttgtgct
    78361 tcttgtgctg gttgttcagc ttgtgaatca gctgtagctt ggctaggttt attttccgca
    78421 tcagctactt tggcatctgg tttagtagaa tcaggtctag cttctggagc tgggtcttga
    78481 tgttcaggct tggaaggggt tgagtctggt ttctcttctg cagttgactc atggctagtt
    78541 ccattttgag agactcgaag aacagtagct gtaagggcat tcaatttcaa gcctttttca
    78601 gtccattcaa gtcctttcgg gttggcaatt ccgactggtc ctgcttggtt ttcatctgcc
    78661 aaaacttccg catttcttag atgtgcaaag gcagttccca aattaaattc gcgagctttt
    78721 tcatccgcat tgacaaagac tgcgtagata tcgccgtttg gagcagtgat ttggtagcca
    78781 atcactacat cctctttttc cacaccattt tggcctggga cagtgatgag gtggacacgg
    78841 tctttgatat cttggagact cttaagtcgg aaggcatctg tagattgacg aagggcaatc
    78901 aaacctttca tatagtcacg gctcttgaca ttttcaggat aagctttacc atctgtagcc
    78961 ttagtccagt caaacttgtt gactgcgtcg ctagaatcgt aagaatcatg gatgaagtaa
    79021 ggatagtcaa atgggttgcc gtccttatca cgcaacaagt gagatttgtt tggaacctta
    79081 tcctctgcta ctggagtctt gtaggctggg tcacggaatt gtttagtacg tccatattcc
    79141 tgaccggagt ggataaatgg agttccttga gctgtcaaga ccatgagatt tccaagtcgt
    79201 aaacgacggt ggatttcagc atagttctca gccttgcttg ggtctttttt gatagactgg
    79261 gcaatgatgt caaagagggt caagttatca tgggctgcga tgtattggat gacatctcca
    79321 gggctgtcag cttcaaagtt agttggttga gcaatgagat ttttaaagat ggtgttgaca
    79381 tcacgcttgc cacctgtgat aaaggcaggt tgaccttcgt ttggataacc agatttgagg
    79441 ttgttacgga tgtcatctga aaagacagcg acagtatcgg tatgtttcat ccaatcttgg
    79501 tcagcagctt tagtaggcat gttttcatca ccggcatagg ttctccaacc ttcgcctaac
    79561 atgattagat ttggattgag ggcgcgtgca gccttgtaag cttcttcgat agaagcggcg
    79621 tcatggtctc ccatcatatc gaagcggaag ccatccactt tgtaggtatc aactaggtat
    79681 ttgatagagt caactaggag gcgtttggtc atatggtggg ttgtccccaa gcgtccacca
    79741 ccaaagctag ttcgaggtgt gccatcggca tccataaagt ggtagtagtt tggctctagg
    79801 tcttcaaaga tatcgacttt ggctgtgtgg ttataaacga catctaggat agctcccata
    79861 ccacgtttgt ggatttcgtt gatgaggttt ttaaattctg cgattcgttt ttctggattc
    79921 ttaggatcgc ttgagtacat accagtcaag gagaagtagt tttgagggtc atatccccag
    79981 ttgtagttgc tgttgcttga agcatagtca gacaagcgtt catggttttt caattcattg
    80041 acaaagtagt aagacaagac tggaaggagc tggatatggg ttacacccaa gtctttgaga
    80101 tagtctagtt tttcaatgaa ggcttcaaaa gtcccaaatg gtttggtcaa gtcttttgca
    80161 atggcaggat ctgaagtgaa gtcacgcaca tgagcttcgt agataacggc gtcttcacga
    80221 gtcttgaaat tgtgaatctt accataagtc aagtcttgag gtccgagttt agctggatct
    80281 acaaaggcgg ctttagccac tttatgggca tcgtcaatct tggcatcgtt gctattccaa
    80341 gcagcaagag atttagcgta aggatcgagt gcaagaacag ttttaccttg acgctcgatt
    80401 tggtattgat aatagtagcc agtgaaatct gtgattccga gtttgtttgt gctgtctaga
    80461 gtttgtttcc aagttcctct ttcccctttt tcgagagcga cagttccaac tactttgtca
    80521 gggtcattct tgtcgtagac aacaacagaa accttatcag cacttggtga ccaaagggtc
    80581 aaatcaactt gttttccttc ttcttttagg tcagctccca gtttgccatc atagctgtat
    80641 gtctcatctt tcaggcgcca gcttgttttg gtagtgaatt ggtcggaatt gtagctaaca
    80701 gtataaggat gttttgtgtc agagaaatct ccgctgtagg tcactttctt accagcttca
    80761 tcgattgcaa catcggtaat agttaccttg tttcctaggt gattagtgat gttggagtgt
    80821 ttgaggatat cttctttttt agcaccgaca agtgttgaaa agctactttc aatgctagaa
    80881 gtgcctacgt gttgggctcc tgtcatacgg atatcatgga catagtatgg atttgtgtaa
    80941 atcgattcat catcgtcttt taggaaaatt tggctatgat ttttcaaatc tgtgaactta
    81001 taattttctt tacggatttt cacgtcgtct ccttgtttgc tctcatctag taataaaaat
    81061 ccaaattctc ttgcggcttc attaagagga atgtcgatat agcggccata tttgcctgta
    81121 gccgtaaagt ctgttccgtc aggccattga gcgctacttg gatttttcac atctccccag
    81181 taccagagag atttcttgtc atagttgcca tctgtgcggt agtagttgac gcgaacagtt
    81241 cctgcaggct gtggctcgta agagaaaacc ttgtaatctt ggtctaacca agcttcgttc
    81301 atttttggaa ctagtttttc tacagattta tcgccggtta gattttttcc agctgtattg
    81361 ttgatgagga agctaatttt cttggcttgt tctcccttta atttgacatc taggtaatag
    81421 ccgtagtcat ctttcttggc atccttgaag gacaaagctc cgtttggcca gttttcagat
    81481 ggtttttcaa catcgtccca agtccatagt ccttgagcat ccttgttttc ttcaggaagt
    81541 tttttgacat ggatacggaa gtagttatct tcgatgggct cttctgcctt agtttcagtt
    81601 gttactggac tagtagaagt agttggctca cttgaacgat cttgtccagt ttgtggtgct
    81661 ggatcggctg ggcttgcagc aggagttgtt ggctctgttg caggtttttc ttctgttttc
    81721 tctagggaag cgtttgcatt tccaagtgaa gaaatatcac ttttgttctt accagagcca
    81781 gctgctgtat cagtaagagg ttgggcaagg gtggttgtat ttctgttgtt gggttcgtta
    81841 gtggttggtg tactttcgtc ggatgagata gttggtgtag ccatggcaag caagacaagg
    81901 cttgcgccga taaggacaga accagtccca tttttgaggg aacggatgct gtagaccatt
    81961 tttttctcag tgtgagatgg tgtttttctc ataatgattc tccaatcaat aaatttctat
    82021 atcagtatag catgtagtaa aacaatatgc aagcgttttc tttgatttgt gaaaaaaatt
    82081 cttacttttg agaagttttc tgtactattt tatatatcag tataaatgac ggagataaaa
    82141 atgtcacata agccaagccg tattattagg aagatgatgt gttcccagct atttttattc
    82201 agaaattgat ctctaacatt accaataaaa aagaaaaata tcttgacaaa caagggaaaa
    82261 ttttgttaca ataatagacg gtacttttta cttttggtct ctcaagagtg tacagggacg
    82321 tgctgacaaa tgttgcaaaa gtacacacag atgatatctg tcaccaagtg tatcatcacc
    82381 aaaaataaaa aaacacagga gaatgtagat gcctacaatt aaccaattgg ttcgcaaacc
    82441 gcgtaaatca aaagtagaaa aatctaaatc accagctttg aacgttggtt acaatagtca
    82501 taaaaaagtt caaacaaacg tttcttcacc acaaaaacgt ggtgttgcaa ctcgtgttgg
    82561 aacaatgaca cctaaaaaac ctaactcagc ccttcgtaaa ttcgctcgtg tacgtttgag
    82621 caaccttatc gaagttactg cctacatccc aggtatcgga cacaacttgc aagagcacag
    82681 cgtggtgctt cttcgcggtg gacgtgtaaa agaccttcca ggggtacgtt accatatcgt
    82741 ccgtggtgca cttgatactg caggtgttaa cgatcgtaaa caaggtcgtt ctaaatacgg
    82801 tactaaacgt ccaaaagcat aaggaaaggg gataaagaga aatgagtcgt aaaaatagag
    82861 ctccaaaacg tgacgtattg ccagatccgc tatacaattc acaactagtt actcgtctta
    82921 tcaaccgcgt tatgcttgat ggtaaacgtg gtactgctgc ttcaatcgtt tacggtgctt
    82981 ttgagcaaat caaagaagct actggcaacg atgcacttga agtatttgaa acagctatgg
    83041 aaaacatcat gcctgtactt gaagtacgtg cacgtcgtgt tggtggttct aactaccaag
    83101 tcccagttga agttcgtcca gaacgtcgta caacacttgg acttcgttgg ttggtaacaa
    83161 tcgctcgtct tcgtggtgaa cacacaatgc aagaccgtct tgcaaaagaa atcttggatg
    83221 ctgctaacaa cactggtgca gctgttaaga aacgtgaaga tactcaccgt atggctgaag
    83281 ctaaccgtgc attcgcacac ttccgttggt aagataggat gcgaaagcgt taagaaagtc
    83341 ccagagaaaa tagggaatcg aagcaggttg cggttgcaac caatgagatt catctttttc
    83401 tccagacttt tagcttgagc tcaactaaat catgatgcta ggcacggtaa ggatgcaagg
    83461 tgaaaatagg aaactgacgc agtattcaac gaatacaagg agttttatct ttttcacgca
    83521 gcatcccgtt ccagctcaca tcggctaact aactttagcc cgggttcaaa ttagctaaat
    83581 cgattagtat tagctataac tcagcttacc atctcgtaag ttgaaaccaa caatagcatg
    83641 aaaacattga gaacgggtag gtcctgccta tccgttttta ttaaaatcgt gttataatag
    83701 aatagaaatc aaaaataaat aggagaaaca aacctcatgg cacgcgaatt ttcacttgaa
    83761 aaaactcgta atatcggtat catggctcac gtcgatgccg gtaaaacaac aactactgag
    83821 cgtattcttt actacactgg taaaatccac aaaatcggtg aaactcacga aggtgcgtca
    83881 caaatggact ggatggagca agagcaagaa cgtggtatca cgatcacatc tgctgcgaca
    83941 acagctcaat ggaacaacca ccgcgtaaac atcatcgaca caccaggaca cgtggacttc
    84001 acaatcgaag tacaacgttc tcttcgtgta ttggatggtg cggttaccgt tcttgactca
    84061 caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaactga gtacggagtt
    84121 ccacgtatcg tatttgccaa caaaatggac aaaatcggtg ctgacttcct ttactctgta
    84181 agcacacttc acgatcgtct tcaagcaaat gcacacccaa tccaattgcc aatcggttct
    84241 gaagatgact tccgtggtat cattgacttg atcaagatga aagctgaaat ctatactaac
    84301 gaccttggta cggatatcct tgaagaagac atcccagctg aataccttga ccaagctcaa
    84361 gaataccgtg aaaaattgat tgaagcagtt gctgaaactg acgaagaatt gatgatgaaa
    84421 tacctcgaag gtgaagaaat cactaacgaa gaattgaaag ctggtatccg taaagcgact
    84481 atcaacgttg aattcttccc agtattgtgt ggttcagcct tcaaaaacaa aggtgttcaa
    84541 ttgatgcttg atgcggttat cgactacctt ccaagtccac ttgacatccc agcaatcaaa
    84601 ggtattaacc cagatacaga cgctgaagaa actcgtccag catctgacga agagccattt
    84661 gcagctcttg ccttcaagat catgactgac ccattcgtag gtcgtttgac attcttccgt
    84721 gtttactcag gtgttcttca atcaggttca tacgtattga atacttctaa aggtaaacgt
    84781 gaacgtatcg gacgtatcct tcaaatgcac gctaacagcc gtcaagaaat cgacactgtt
    84841 tactcaggtg atatcgctgc tgccgttggt ttgaaagata ctacaactgg tgactcattg
    84901 acagatgaaa aatctaaaat catccttgag tcaatcaacg ttccagaacc agttatccaa
    84961 ttgatggttg agccaaaatc taaagctgac caagacaaga tgggtatcgc ccttcaaaaa
    85021 ttggctgaag aagatccaac attccgcgtt gaaacaaacg ttgaaactgg tgaaacagtt
    85081 atctcaggta tgggtgaact tcaccttgac gtccttgttg atcgtatgcg tcgtgagttc
    85141 aaagttgaag cgaacgtagg tgcgcctcaa gtatcttacc gtgaaacatt ccgcgcttct
    85201 actcaagcac gtggattctt caaacgtcag tctggtggta aaggtcaatt cggtgatgtg
    85261 tggattgaat ttactccaaa cgaagaaggt aaaggattcg aattcgaaaa cgcaatcgtc
    85321 ggtggtgtgg ttcctcgtga atttatccca gcggttgaaa aaggtttggt agaatctatg
    85381 gctaacggtg ttcttgcagg ttacccaatg gttgacgtta aagctaagct ttatgatggt
    85441 tcatatcacg atgtcgactc atctgaaact gccttcaaga ttgcggcttc actttccctt
    85501 aaagaagctg ctaaatcagc acaaccagct atccttgaac caatgatgct tgtaacaatc
    85561 actgttccag aagaaaacct tggtgatgtt atgggtcacg taactgctcg tcgtggacgt
    85621 gtagatggta tggaagcaca cggtaacagc caaatcgttc gtgcttacgt tccacttgct
    85681 gaaatgttcg gttacgcaac agttcttcgt tctgcatctc aaggacgtgg tacattcatg
    85741 atggtatttg accactacga agatgtacct aagtcagtac aagaagaaat tattaagaaa
    85801 aataaaggtg aagactaatc cgtcctcact ctagaaggaa gtcacttagt ggcttccttt
    85861 tgtctttaga aaatacctct aaatatggta aaatagtaga agaataatgt gaggaaaatg
    85921 aatgtcaaat agttttgaaa ttttgatgaa tcaattgggg atgcctgctg aaatgagaca
    85981 ggctcctgct ttagcacagg ccaatattga gcgagttgtg gttcataaaa ttagtaaggt
    86041 atgggagttt catttcgtat tttctaatat tttaccgatt gaaatctttt tagaattaaa
    86101 gaaaggtttg agcgaagaat tttctaagac aggcaataaa gctgtttttg aaattaaggc
    86161 tcggtctcaa gaattttcaa atcagctctt gcagtcctac tatagggagg ttttctctga
    86221 aggtccatgt gctagtcaag gttttaagtc cctttatcaa aatttgcaag ttcgtgctga
    86281 gggtaatcag ctatttattg aaggatctga agcgattgat aaggaacatt ttaagaagaa
    86341 tcatcttcct aatttagcca aacaacttga aaagtttggt tttccaactt ttaactgtca
    86401 agtcgagaag aatgatgtct tgacccaaga gcaggaagag gcctttcatg ctgaaaatga
    86461 gcagattgtt caagctgcca atgaggaagc gctccgtgct atggaacaac tggagcagat
    86521 ggcacctcct ccagcggaag agaaaccagt ctttgatttt caagcgaaaa aagctgcagc
    86581 taaacccaag ctggataagg cggagattac tcctatgatc gaagtgacga cagaggaaaa
    86641 tcgtctggta tttgaagggg ttgtttttga tgtggagcaa aaagtgacta gaacaggtcg
    86701 tgttttaatc aactttaaaa tgacggacta tacttcaagt ttttctatgc aaaagtgggt
    86761 taaaaacgag gaagaggccc agaagtttga cctcatcaag aagaattctt ggctccgagt
    86821 tcgagggaat gtggagatga ataatttcac acgcgatttg actatgaacg tacaggatct
    86881 gcaggaagtt gttcactatg agcggaagga tttgatgcca gaaggtgagc gtcgggttga
    86941 gtttcatgct catactaaca tgtcgactat ggatgctttg ccagaggtcg aagagattgt
    87001 tgcaacagct gctaagtggg gacacaaggc ggttgctatc acggaccatg ggaatgtcca
    87061 gtcctttcca catggctata aggcggctaa gaaagcggga atccagctga tctatggaat
    87121 ggaagccaat atcgtggagg accgtgtccc tatcgtctat aacgaagtgg agatggactt
    87181 gtcagaagca acctacgtgg tctttgacgt ggaaacgacg ggactttcag ctatctataa
    87241 tgacttgatt caggttgcgg cctctaagat gtacaagggg aatgttattg ctgaatttga
    87301 tgaatttatc aatcctgggc atcccttgtc agcttttact acagagttaa ctggaattac
    87361 agatgatcat gtcaaaaatg ccaaaccact agaacaagtt ttgcaagaat tccaagaatt
    87421 ttgcaaggat acggtcctag ttgcccacaa tgctaccttt gacgttggct ttatgaatgc
    87481 taattatgag cgtcatggtc ttccaaagat tagtcagcca gttattgata cgctggagtt
    87541 tgctagaaac ctctatcctg agtataaacg ccatggtttg gggcctttga ccaagcgttt
    87601 tggtgtggcc ttggaacatc atcacatggc caactacgat gcggaagcga ctggtcgtct
    87661 gcttttcatc tttatcaaag aggtagcaga aaaacatggt gtgaccgatt tagctagact
    87721 caacattgat ctaatcagtc cagattctta caaaaaagct cggatcaagc atgcgaccat
    87781 ctatgtcaag aatcaggtag gtctaaaaaa tatctttaag ctggtttcct tgtctaatac
    87841 caagtatttt gaaggagtgc cacggattcc gagaacggtt ctagatgccc atcgagaggg
    87901 cttgatttta ggttcagcct gttcagaggg tgaagttttt gacgtggtcg tttctcaagg
    87961 tgtggatgcg gcggttgagg tggccaagta ttatgacttt atcgaggtca tgccaccggc
    88021 tatctatgcg cccttgattg ccaaagagca ggtcaaggat atggaggaac tccagaccat
    88081 tatcaagagt ttgatagagg ttggagatcg ccttggcaag cctgttctgg ctacgggaaa
    88141 tgttcactat atcgaaccgg aagaagagat ttatcgtgaa attatcgtcc gtagtttggg
    88201 acagggtgcg atgattaacc gaactatcgg tcatggtgaa catgcccaac cagcaccact
    88261 tccaaaggct cattttcgaa cgactaatga gatgttggat gaatttgcct ttttgggaga
    88321 ggaactggct cgtaaactgg ttattgaaaa caccaatgcc ttggcagaaa tatttgaacc
    88381 cgttgaagtc gttaagggtg acttgtatac gcctttcatc gacaaggctg aagaaacagt
    88441 tgctgagttg acctataaga aagcttttga gatttatgga aatccgctgc cagatattgt
    88501 tgatttgcgg attgaaaaag aattaacatc catactgggg aatggatttg ctgtgattta
    88561 tctggcatcg cagatgctgg tgcaacgttc taatgaacgg ggttatttgg ttggttctcg
    88621 tgggtctgtc ggatctagtt tcgttgcgac catgattggg attacggaag tcaatcctct
    88681 ctctcctcac tatgtctgtg gtcagtgtca gtacagtgag tttatcacag atggttcgta
    88741 cggttcagga tttgatatgc cccataagga ctgtccaaac tgtggtcaca aactcagtaa
    88801 aaacggacag gatattccgt ttgagacctt ccttggtttt gatggggata aggttcctga
    88861 tattgacttg aacttctcgg gagaagatca gcctagcgcc cacttggatg tgcgtgatat
    88921 ctttggtgaa gaatatgcct tccgtgcggg aacggttggt acggtagctg ccaagactgc
    88981 ctatggattt gtcaagggtt acgagcgaga ttatggtaag ttttatcgtg atgcagaagt
    89041 agaacgcctc gctcaaggag cggcgggtgt caagcggaca acaggccaac acccgggggg
    89101 aatcgttgtt attccgaact acatggatgt ctacgatttt acgcctgtcc agtatccagc
    89161 agatgatgtc acggctgaat ggcagaccac tcactttaac ttccacgata tcgatgagaa
    89221 cgtcctcaaa ctcgatgtac tgggacatga tgatccgacc atgattcgaa aacttcagga
    89281 tttgtctggt attgacccta ataaaattcc tatggatgac gaaggcgtga tggcactctt
    89341 ttctgggact gatgtgctag gggtaacacc tgaacaaatt ggaacgccta cgggtatgtt
    89401 ggggattcca gagtttggaa caaatttcgt acgtggaatg gtagacgaaa cccatccgac
    89461 aacctttgcg gaattgcttc agctgtctgg tctgtcccac ggtactgacg tttggttggg
    89521 gaatgctcag gatctgatta agcaaggaat agcggaccta tcgactgtta tcggttgtcg
    89581 ggacgacatc atggtttacc tcatgcatgc gggtctggaa cctaagatgg cctttaccat
    89641 tatggaacgg gtacgtaagg gtttgtggct aaagatttca gaagaggaga gaaatggcta
    89701 tatcgaagca atgaaggcta ataaggtgcc agagtggtat atcgaatcct gtgggaaaat
    89761 taagtacatg ttccctaagg cccatgcggc agcctacgtt atgatggcct tgcgtgtagc
    89821 ttacttcaag gttcaccatc ctatttatta ctactgtgct tacttctcca ttcgtgctaa
    89881 ggcttttgat atcaagacca tgggtgcggg cttggaggtc atcaagcgca gaatggaaga
    89941 aatctctgaa aaacggaaga acaatgaagc ctctaatgtg gaaatcgatc tctatacaac
    90001 tcttgagatt gtcaatgaga tgtgggaacg aggtttcaag tttggtaaat tagatctcta
    90061 ctgtagtcag gcgacagagt tcctcatcga cggggatacc cttatcccac catttgtagc
    90121 aatggatggt ctgggagaga acgttgccaa gcaactggtg cgggcgcgtg aagagggaga
    90181 atttctctct aaaacagaac tacgcaagcg tggtggactc tcatcaacct tggttgaaaa
    90241 gatggatgag atgggtattc ttggaaatat gccagaggat aaccagttga gtttgtttga
    90301 tgagttgttt taaaaaattg cttaataatc tattaaaaga ggctaacgta tatccaatag
    90361 atttacatta gctttctttt ttgttaaaat agtctatgga aagagggtga gagtatgtca
    90421 aagatgagta taagcatccg tctggatagt gaggttaagg agcaggccca acaggtgttt
    90481 agtaatctgg gaatggatat gacaacagct attaatattt tccttcgtca ggcaattcaa
    90541 tatcagggac taccttttga tgttagacta gacgaaaatc ggaagttgct ccaagcgtta
    90601 acggatttag accaaaatcg taatatgagc cagtcttttg aatcagtctc agatttgatg
    90661 gaggacttac gtgcttaaga ttcgttatca taaacagttt aaaaaagatt ttaagttggc
    90721 tatgaagcgt ggtttgaagg cagaattatt agaagaagtt ttgaattttc tggttcaaga
    90781 aaaagaacat cctgccagat atcgtgatca ttcattgacg gcatccaagc attttcaagg
    90841 agttcgtgaa tgccataccc agccagattg gcttttggtt tataaagtag acaagtcgga
    90901 attgatttta aatttgctga ggacaggcag tcacagtgat ttattttaat ctattttaag
    90961 ggggttctca tgaaactaag aatatttgcg gaagataagc cggctaagaa ggtatttgaa
    91021 tatcaattag aacttgctga tcgtacaatt cttctatcga cagcactctt gtcaggtgct
    91081 attgctttag caggaatctt ttctgctttg agagaaaaat aaaaatagaa aagagaaaac
    91141 agaatggttt taccaaattt taaagaaaat ctagaaaaat atgcgaaatt gttggttgcg
    91201 aacggaatta acgtgcaacc tggtcacact ttggctctct ctattgatgt ggagcaacgt
    91261 gaattggcac atctaatcgt gaaagaagct tatgccttgg gtgcgcatga ggtcatcgtt
    91321 cagtggacag atgatgtgat taaccgtgag aaattcctcc atgccccgat ggagcgtttg
    91381 gacaatgtgc cagaatacaa gattgctgag atgaactatc tcttggagaa taaggctagc
    91441 cgtcttggag ttcgttcatc tgatccaggt gccttgaacg gagtggacgc tgacaagctt
    91501 tcagcttctg ctaaagctat gggacttgcc atgaagccta tgcgtatcgc aactcaatct
    91561 aacaaggtta gctggactgt agcagctgca gcaggacttg agtgggctaa gaaagtcttc
    91621 ccaaatgctg cgagcgacga agaagcagtt gatttccttt gggaccaaat tttcaaaact
    91681 tgccgtgtct acgaagcaga tcctgttaag gcctgggaag agcatgcagc tatcttgaag
    91741 agcaaggccg atatgcttaa taaggagcaa ttttcagccc ttcactacac agcgccagga
    91801 acagatttaa cacttggttt gccaaagaac catgtttggg aatcagctgg tgctgtcaat
    91861 gcacagggcg aaggattctt gccaaatatg ccgacagaag aggtcttcac agcacctgac
    91921 ttccgtcgtg cagatggtta tgtcacttct acaaaaccgc ttagctacaa cggaaatatt
    91981 attgaaggca ttaaggtgac ctttaaggat ggacaaatcg tagatatcac tgctgagaag
    92041 ggtgatcagg ttatgaaaga ccttgtcttt gaaaatgcgg gtgcgcgtgc cttgggtgaa
    92101 tgtgccttgg taccagatcc aagtccaatt tctcagtcag gcattacctt ctttaacacc
    92161 cttttcgatg aaaatgcgtc aaaccacttg gctatcggtg cagcctatgc gactagcgtt
    92221 gttgatggag cggagatgag cgaagaggag cttgaagctg cagggcttaa ccgttcagat
    92281 gttcacgtag actttatgat tggttctaac caaatggata tcgatggtat tcgtgaggat
    92341 ggaacgcggg tacctctttt ccgtaatggg aattgggcaa attaaggaga taatatgtta
    92401 ggaagtatgt tcgttggtct cctagtggga tttttagcag gtgctatgac caatcgtgga
    92461 gagcgaatgg gatgttttgg aaaaatgttt ctcggttgga tcggagcctt tctaggtcac
    92521 ttgctctttg gaacttgggg gccagtttta tcaggaacag ctattatccc agctgtttta
    92581 ggtgccatga ttgtcttagc tattttttgg agacgaggaa gttaatttcc taaatctgat
    92641 actcaatgaa aatcaaagag caaactagga aactagccgc aggttgctca aagcactgct
    92701 ttgaggttgc agatagaact gacgaagtca gtaacatata tgcggcaagg cgacgttgac
    92761 gcggtttgaa gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc
    92821 ctccttttga tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg
    92881 gtgggaagtc ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt
    92941 aaaaaagaaa aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat
    93001 gggcaagtgt tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt
    93061 atctcagcga ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg
    93121 cggagtaagg aagtttttcc agtaggacgc ttggatattg acacgcatgg tcttttgctc
    93181 ttgaccaata atggtcagct ggctcatgtt cttctttctc ccaagcgtca tgtggacaag
    93241 acttatcagg ctcaggtcaa gggaattatg acccaagaag atgtggagac atttatcaag
    93301 ggcattccgc tcaaagactt tacctgtcag cccgctagac tggagattct ttccacagat
    93361 gcagaaaaga atcagagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc
    93421 aagcgtatgg tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga
    93481 actttagtat tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa
    93541 ttagaaattc tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga
    93601 gcaaactagg aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt
    93661 ttgaagagat tttcgaagag tataaattcg aaaaaggtga gggagaatgt ccttaccttt
    93721 tatgtttttt agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag
    93781 gaatctatga acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca
    93841 aatgtaaaat accaagcgat tgaaaatgct gctagccaca acggaatttt tgcagctctg
    93901 gaacgtcgcc aaagccatgt agacaacaca cctgttttct cattggattt aaccaaggac
    93961 aaggtcacta accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc
    94021 cgccacaaac tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact
    94081 ttcttctggg ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca
    94141 gaccaagaat tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggt
    94201 ggtcaatggg atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt
    94261 tatcctgagt ctgtttcatc tagcagcagt cgtgagctaa atgcgatcct taataaattg
    94321 cttcgtcaag atgctcaaat cttgcgtgac ttgcttgttt ctggtgcaga tcaagcgact
    94381 gttcaagcta agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta
    94441 ggacttccac cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt
    94501 gaaaaaggaa tcacaccaca agagttttac aagaaatatg tcaatcttcc tttagaagac
    94561 tacgtttctg ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt
    94621 gagatgttgg ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag
    94681 cgcttgaaag aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct
    94741 gatgtcggcc agctcagtaa ccgtaaggct ggcatccttg cgacagatgt ttatgacttt
    94801 gaatcaagca tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa
    94861 agcttgatga cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca
    94921 accaagtgga aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt
    94981 gcctcagacg cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg
    95041 acagcagaag aacaagctgc ctatggagca gaaccaatcg tacttgcacc atgggatcca
    95101 atgggagcct tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc
    95161 ctttttagtt gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga
    95221 gggcaaggat aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag
    95281 taaggagtag tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa
    95341 ctttttcagg agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt
    95401 tagacccttc tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag
    95461 aaacatcgaa agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca
    95521 tcccaaggat agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag
    95581 tgatttctga tccagccttg tatccaatct cttgaacata ccacaagaat gacatacgaa
    95641 tcaagttcca tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg
    95701 aagcaccgag agatccaagg attgggcgta ctgtaaacca gaatactggg tcaccgatac
    95761 cagcaagagg tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca
    95821 caccgttagc acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt
    95881 atggatgagt gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt
    95941 tagtatagag ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc
    96001 gttcaaagtt ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg
    96061 atttagttaa ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc
    96121 ttctaggata tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc
    96181 agttttagaa aggtgaaggt agataagagc gatagcaaca ccgatagcac cgaatccgat
    96241 tagagtaata tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc
    96301 acgagttgcc atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc
    96361 gatagccata ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc
    96421 agttggtacc ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag
    96481 cgcaatgaaa tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc
    96541 agtatgaacc aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac
    96601 ggcaagaggg atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc
    96661 aagaaccatg ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc
    96721 accgatattt gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc
    96781 ttccaagtga cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg
    96841 gaactggtcg aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat
    96901 agaaataata gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt
    96961 gttaatcaag tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc
    97021 aacacccaag tcacgcattt tttcaaatgt agcaacatct tctttgtcca tagacaaaac
    97081 ggtattgacc aatgttttac ctgttgagtg agccatagaa ccaacgttaa gagtcttgat
    97141 tggcacgccg ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc
    97201 atgtgtttct ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac
    97261 gttagccttg acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt
    97321 agccacgtta tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt
    97381 tgcaacctga ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc
    97441 gtctccgata acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct
    97501 tgcaacttct tcaactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc
    97561 tttaatgata ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt
    97621 gtaggcttga atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg
    97681 attttctccc atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa
    97741 aactagaacc tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag
    97801 atcatcagga ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa
    97861 gatcatagat cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat
    97921 tccgatactc attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt
    97981 aagactgttt aagtataaac cgttt
//
LOCUS       DAVKUR010000003        72948 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKUR010000003 DAVKUR010000000
VERSION     DAVKUR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72948
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.003"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1357)
                     /locus_tag="VW749_000245"
     CDS             complement(<1..1357)
                     /locus_tag="VW749_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0174353.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QS"
     gene            complement(1604..1972)
                     /gene="rplL"
                     /locus_tag="VW749_000246"
     CDS             complement(1604..1972)
                     /gene="rplL"
                     /locus_tag="VW749_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0174354.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(2048..2548)
                     /locus_tag="VW749_000247"
     CDS             complement(2048..2548)
                     /locus_tag="VW749_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0174355.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(2587..2722)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(2798..4057)
                     /locus_tag="VW749_000248"
     CDS             complement(2798..4057)
                     /locus_tag="VW749_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0174356.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKCPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(4449..6197)
                     /locus_tag="VW749_000249"
     CDS             complement(4449..6197)
                     /locus_tag="VW749_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174357.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLVIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(6199..7923)
                     /locus_tag="VW749_000250"
     CDS             complement(6199..7923)
                     /locus_tag="VW749_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174358.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(7981..8919)
                     /gene="msrB"
                     /locus_tag="VW749_000251"
     CDS             complement(7981..8919)
                     /gene="msrB"
                     /locus_tag="VW749_000251"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0174359.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(9067..9138)
                     /locus_tag="VW749_000252"
                     /pseudo
     CDS             complement(9067..9138)
                     /locus_tag="VW749_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9214..10083)
                     /locus_tag="VW749_000253"
     CDS             complement(9214..10083)
                     /locus_tag="VW749_000253"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0174360.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAAAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(10085..11371)
                     /locus_tag="VW749_000254"
     CDS             complement(10085..11371)
                     /locus_tag="VW749_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0174361.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(11522..12259)
                     /gene="mecA"
                     /locus_tag="VW749_000255"
     CDS             complement(11522..12259)
                     /gene="mecA"
                     /locus_tag="VW749_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0174362.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(12459..13493)
                     /locus_tag="VW749_000256"
     CDS             complement(12459..13493)
                     /locus_tag="VW749_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0174363.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(13522..14958)
                     /locus_tag="VW749_000257"
     CDS             complement(13522..14958)
                     /locus_tag="VW749_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0174364.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNNVSLLSTLLFLL
                     VSSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVM
                     VSILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRL
                     FERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSF
                     IAANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAM
                     GVLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPV
                     LDYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYI
                     MELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSE
                     SFFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(14974..15960)
                     /locus_tag="VW749_000258"
     CDS             complement(14974..15960)
                     /locus_tag="VW749_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0174365.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(15962..17065)
                     /locus_tag="VW749_000259"
     CDS             complement(15962..17065)
                     /locus_tag="VW749_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0174366.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(17055..17900)
                     /locus_tag="VW749_000260"
     CDS             complement(17055..17900)
                     /locus_tag="VW749_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0174367.1"
                     /translation="MNNMTDLKAIQARSLEMADYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(18179..19453)
                     /gene="psr"
                     /locus_tag="VW749_000261"
     CDS             complement(18179..19453)
                     /gene="psr"
                     /locus_tag="VW749_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0174368.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(19450..20298)
                     /gene="pheA"
                     /locus_tag="VW749_000262"
     CDS             complement(19450..20298)
                     /gene="pheA"
                     /locus_tag="VW749_000262"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0174369.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(20295..20771)
                     /locus_tag="VW749_000263"
     CDS             complement(20295..20771)
                     /locus_tag="VW749_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0174370.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(20764..22047)
                     /gene="aroA"
                     /locus_tag="VW749_000264"
     CDS             complement(20764..22047)
                     /gene="aroA"
                     /locus_tag="VW749_000264"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0174371.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSASFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(22139..22477)
                     /locus_tag="VW749_000265"
     CDS             complement(22139..22477)
                     /locus_tag="VW749_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0174372.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(22488..23591)
                     /locus_tag="VW749_000266"
     CDS             complement(22488..23591)
                     /locus_tag="VW749_000266"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0174373.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            complement(23601..24767)
                     /gene="aroC"
                     /locus_tag="VW749_000267"
     CDS             complement(23601..24767)
                     /gene="aroC"
                     /locus_tag="VW749_000267"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0174374.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(24777..25844)
                     /locus_tag="VW749_000268"
     CDS             complement(24777..25844)
                     /locus_tag="VW749_000268"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0174375.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(25863..26717)
                     /locus_tag="VW749_000269"
     CDS             complement(25863..26717)
                     /locus_tag="VW749_000269"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0174376.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(26707..27384)
                     /locus_tag="VW749_000270"
     CDS             complement(26707..27384)
                     /locus_tag="VW749_000270"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0174377.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(27381..28544)
                     /locus_tag="VW749_000271"
     CDS             complement(27381..28544)
                     /locus_tag="VW749_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0174378.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(29229..30863)
                     /locus_tag="VW749_000272"
     CDS             complement(29229..30863)
                     /locus_tag="VW749_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174379.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSLMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVDPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(30844..31593)
                     /locus_tag="VW749_000273"
     CDS             complement(30844..31593)
                     /locus_tag="VW749_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174380.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            31772..33226
                     /locus_tag="VW749_000274"
     CDS             31772..33226
                     /locus_tag="VW749_000274"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0174381.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(33316..35934)
                     /gene="alaS"
                     /locus_tag="VW749_000275"
     CDS             complement(33316..35934)
                     /gene="alaS"
                     /locus_tag="VW749_000275"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0174382.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(35956..36441)
                     /locus_tag="VW749_000276"
     CDS             complement(35956..36441)
                     /locus_tag="VW749_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0174383.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(36716..36955)
                     /locus_tag="VW749_000277"
     CDS             complement(36716..36955)
                     /locus_tag="VW749_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174384.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(37224..38294)
                     /locus_tag="VW749_000278"
     CDS             complement(37224..38294)
                     /locus_tag="VW749_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0174385.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGSEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(38291..39064)
                     /locus_tag="VW749_000279"
     CDS             complement(38291..39064)
                     /locus_tag="VW749_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174386.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(39061..39867)
                     /locus_tag="VW749_000280"
     CDS             complement(39061..39867)
                     /locus_tag="VW749_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174387.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(39848..41005)
                     /locus_tag="VW749_000281"
     CDS             complement(39848..41005)
                     /locus_tag="VW749_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174388.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(41166..42071)
                     /gene="murB"
                     /locus_tag="VW749_000282"
     CDS             complement(41166..42071)
                     /gene="murB"
                     /locus_tag="VW749_000282"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0174389.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(42183..42935)
                     /locus_tag="VW749_000283"
                     /pseudo
     CDS             complement(42183..42935)
                     /locus_tag="VW749_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(42945..43676)
                     /gene="budA"
                     /locus_tag="VW749_000284"
     CDS             complement(42945..43676)
                     /gene="budA"
                     /locus_tag="VW749_000284"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0174390.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            complement(44160..44681)
                     /locus_tag="VW749_000285"
     CDS             complement(44160..44681)
                     /locus_tag="VW749_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcin A-M57"
                     /protein_id="HEV0174391.1"
                     /translation="MKFKKIVTSALVVLSLFSIMSPSIASVRVFADDVTTTEVSEIST
                     QEQKQIDDVANVLEQMFRNGVNEKNFTEYVYKNFSQKDIALAENELETNINNPYDRVP
                     WDEMGGCIAGKIRDEFFAMINVSLIVKYAQKKAWSELAKVVLRFVKANGLKTNIYIIA
                     GQLAIWAVQCGLE"
     gene            45112..46383
                     /locus_tag="VW749_000286"
     CDS             45112..46383
                     /locus_tag="VW749_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0174392.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(46403..47218)
                     /locus_tag="VW749_000287"
     CDS             complement(46403..47218)
                     /locus_tag="VW749_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0174393.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(47375..48028)
                     /gene="phoU"
                     /locus_tag="VW749_000288"
     CDS             complement(47375..48028)
                     /gene="phoU"
                     /locus_tag="VW749_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0174394.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(48040..48798)
                     /gene="pstB"
                     /locus_tag="VW749_000289"
     CDS             complement(48040..48798)
                     /gene="pstB"
                     /locus_tag="VW749_000289"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0174395.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(48811..49614)
                     /gene="pstB"
                     /locus_tag="VW749_000290"
     CDS             complement(48811..49614)
                     /gene="pstB"
                     /locus_tag="VW749_000290"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0174396.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(49625..50509)
                     /gene="pstA"
                     /locus_tag="VW749_000291"
     CDS             complement(49625..50509)
                     /gene="pstA"
                     /locus_tag="VW749_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0174397.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(50499..51416)
                     /gene="pstC"
                     /locus_tag="VW749_000292"
     CDS             complement(50499..51416)
                     /gene="pstC"
                     /locus_tag="VW749_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0174398.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(51416..52294)
                     /gene="pstS"
                     /locus_tag="VW749_000293"
     CDS             complement(51416..52294)
                     /gene="pstS"
                     /locus_tag="VW749_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0174399.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(52868..54172)
                     /locus_tag="VW749_000294"
     CDS             complement(52868..54172)
                     /locus_tag="VW749_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0174400.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(54173..54946)
                     /locus_tag="VW749_000295"
     CDS             complement(54173..54946)
                     /locus_tag="VW749_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0174401.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(54936..55214)
                     /locus_tag="VW749_000296"
     CDS             complement(54936..55214)
                     /locus_tag="VW749_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0174402.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(55214..55615)
                     /locus_tag="VW749_000297"
     CDS             complement(55214..55615)
                     /locus_tag="VW749_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0174403.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(55825..56442)
                     /locus_tag="VW749_000298"
     CDS             complement(55825..56442)
                     /locus_tag="VW749_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0174404.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(56432..57205)
                     /locus_tag="VW749_000299"
     CDS             complement(56432..57205)
                     /locus_tag="VW749_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0174405.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(57216..57953)
                     /locus_tag="VW749_000300"
     CDS             complement(57216..57953)
                     /locus_tag="VW749_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0174406.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(57958..59088)
                     /locus_tag="VW749_000301"
     CDS             complement(57958..59088)
                     /locus_tag="VW749_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0174407.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(59172..59561)
                     /locus_tag="VW749_000302"
     CDS             complement(59172..59561)
                     /locus_tag="VW749_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0174408.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(59577..59960)
                     /locus_tag="VW749_000303"
     CDS             complement(59577..59960)
                     /locus_tag="VW749_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0174409.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(59961..60749)
                     /locus_tag="VW749_000304"
     CDS             complement(59961..60749)
                     /locus_tag="VW749_000304"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0174410.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(60742..61677)
                     /locus_tag="VW749_000305"
     CDS             complement(60742..61677)
                     /locus_tag="VW749_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0174411.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(61807..61983)
                     /locus_tag="VW749_000306"
     CDS             complement(61807..61983)
                     /locus_tag="VW749_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0174412.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(62123..62830)
                     /locus_tag="VW749_000307"
     CDS             complement(62123..62830)
                     /locus_tag="VW749_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0174413.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            62981..64009
                     /gene="queA"
                     /locus_tag="VW749_000308"
     CDS             62981..64009
                     /gene="queA"
                     /locus_tag="VW749_000308"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0174414.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(64670..65059)
                     /locus_tag="VW749_000309"
     CDS             complement(64670..65059)
                     /locus_tag="VW749_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0174415.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(65163..65804)
                     /locus_tag="VW749_000310"
     CDS             complement(65163..65804)
                     /locus_tag="VW749_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002871528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0174416.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK"
     gene            complement(66518..67069)
                     /locus_tag="VW749_000311"
     CDS             complement(66518..67069)
                     /locus_tag="VW749_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174417.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(67468..68292)
                     /gene="nadE"
                     /locus_tag="VW749_000312"
     CDS             complement(67468..68292)
                     /gene="nadE"
                     /locus_tag="VW749_000312"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0174418.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(68289..69749)
                     /locus_tag="VW749_000313"
     CDS             complement(68289..69749)
                     /locus_tag="VW749_000313"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0174419.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(69865..70353)
                     /locus_tag="VW749_000314"
     CDS             complement(69865..70353)
                     /locus_tag="VW749_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174420.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(70343..70552)
                     /locus_tag="VW749_000315"
     CDS             complement(70343..70552)
                     /locus_tag="VW749_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0174421.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(70937..71665)
                     /locus_tag="VW749_000316"
     CDS             complement(70937..71665)
                     /locus_tag="VW749_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174422.1"
                     /translation="MKLNKLNFLKESIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYAWNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(71681..72472)
                     /locus_tag="VW749_000317"
     CDS             complement(71681..72472)
                     /locus_tag="VW749_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174423.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSMLMKILAQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        21810 a        16263 c        13377 g        21498 t
ORIGIN      
        1 atgattgatc tgctatcttt acaattttgt cgttataaat attacacaac tctctttcat
       61 gaagcttctc cactgcactc ttaaagtcag tatttgttat gtcagttatt tttagtaatt
      121 tattgaattc ctggttctct tctaaacttt ccagtctaat cttttttaag taagataaaa
      181 taaatagagt cttttgttct gcataaataa tgttgttttt atttaaaatt tcttcatagt
      241 aatcttttaa aatatcaatc tcatcattaa aattagtcaa atcctgagag ctagataact
      301 ttgctgcaat gactgcaata cgcggattgc ttttagatat cgtttttata tgttcaattt
      361 cttgattggt aaaatcgttt cgagaaaatt gattgagtaa ttccttaaaa ttatcatctt
      421 ttataagttc tggctcaata ttattgtacc cataaacttt aatattattg attacatctt
      481 ttttagcata atcacgtacc gtaagaataa accgaatatt actagtcgtg ttcagtagcc
      541 caagtgtaga aatataattt tgtgtagtat taacatcatc aataaaaaca atattttctt
      601 tgtgtaaatt tagattgcgt tttacatctt ggtaaatatc ctgattattg ctcttgacac
      661 aaataatgtt atatttattt cgatccagca aagagcaaat ttcaattgct aatctagttt
      721 tccctgttcc aggcttagca gatattaaga agattcgttt ttcacttgat ttaatggtat
      781 ttataatttc acttacatct ccaatatagt catttgatat aggagcatta gttttactct
      841 catcatgaat tcttatgaag tcattgatag accaaacttg ctctgtagat tcactgattg
      901 atagatactc ttttgctaaa tattgaaaat ctatctttgt aagatcatta gcaatttcat
      961 taattccaat caattctaga tgataaggct cagccatttt ttctagatct tctttttgtt
     1021 taattgttat atttgaagaa gtatgacaac aaataagtct cccaacttta tcttcagcaa
     1081 tattttcctc taaaattttt ttcttaactg actgaatgtc tccttctaat ttagatatta
     1141 cagacttatg ggtgccatac ataatataaa catatttacc attttcgaca gcgtaagaat
     1201 ctgggatccc tttagttgtt ttatctgttc cttcctgtga gcctaatgaa acaatattaa
     1261 aattgtattt tctacttagg tacgcgtcac ctagtttttg aaacttccct ccctctagct
     1321 ctttaatatg ttgctcaatt ttatttctta aactcattat aaaaaccttt ccagataagt
     1381 atttcaacat aattatatca cactagtcaa aaccataagg tatagtttaa ttaacaaact
     1441 cttgtactac gttaatttag agtagtaaac caattataca aaaattattt atttcctaaa
     1501 caactatata aaaagtttgc ccctttttaa acaaaaagaa aaaccgctac tcctaagaat
     1561 agcggtttaa tcatgttttt aagctactaa tgtagttgct ctattattta agagtaactg
     1621 aagctccagc ttcttccaat ttagctttga tttcttcagc ttctgcagtt gcaacgcctt
     1681 ctttaacaag tgctggtgca ccgtcaacaa gttctttagc ctctttaaga ccaagaccag
     1741 tgatttcacg tacaactttg ataacgccaa cttttttgtc gcctgcagat gtcaattcaa
     1801 cgtcgaatga atctttagca gcaccagcat cagctgcatc agctgcagca acagctacag
     1861 gagcagctgc agttacacca aattcttctt cgatagcttt tacaaggtcg ttcaattcaa
     1921 ggattgaagc ttctttaatt tcagcaataa tgttttcaat gttcaatgcc attgttattt
     1981 cctccaaata agttttaaat tttataatag tttttttcgt agctaggcta cgctgtgtag
     2041 cttaagatta agccgcgtct tctttgcttt ctgcaaccgc tttgactgca agagcaacgt
     2101 tgcgcactgg cgcttgaagt acagaaagga gcatagaaag aagtccttcg cggtttggaa
     2161 gagttgcaag tgcaagaatc tcttctttag atgcgacagc gccttcgatt gcaccacctt
     2221 taatttcaag tgcttcagcg tttttagaaa agtcgttcaa gattttcgct ggtgcgataa
     2281 catcttcatt agaaaatgct actgcagatg gtccaacaaa tacagatgca agatcttcaa
     2341 gaccagcttt ttcagctgca cgacgcaaga ttgagttttt aataacttta tactcaactt
     2401 cgcttccacg aagctcacga cgaagaactg tatcttgctc aactgtcaaa ccacgagcgt
     2461 ctacaacgac gatagatgca gcagctttca ttttttcagc tactacgtca actagttccg
     2521 cttttttagc aataattgct tcactcatta gtgtgttcac ctccgtaatt attttgcttg
     2581 gggaattttt caaaaagaaa aacgcgccca aacctagaca cgaaagtaca atacgcttct
     2641 ttttacatga tacgttttgt cctcggtagg atatttatga gtcgagctcc cctactgtct
     2701 taggcagttt ttttaaaccg tatataagta tagcatagtc aaaaaaagaa tgcaagattt
     2761 ttgcaaactt tttttaaaat ttttcgtaat ttttctttta aagttctact gtcaggactt
     2821 gaccttgctt aacaacctgt tctccggcga tataaacatc atctacatca ctagatttaa
     2881 ctgcataaac caggtgagac agcatatttt cctgaggttg gagatgaatt ttcccttgtg
     2941 gttgaatgac cagaaaatct gcttgcttgc cgacttccag acttcctatc tgattttcca
     3001 ttccaaggac cttagcccct tcgattgtca gtaccttgag agctgtttcg attggaaact
     3061 ggctggcatc cccacttttc atcttctgaa gaagagctgc agtccttcct tcctcaaaca
     3121 tatctagatt gttattggaa gcaaccgagt cagtcgcaat tccgactgct actcccgctt
     3181 tttggagctg gataattgga gcaattcctg atgccagttt gaggttactg ataggattgt
     3241 gggcgatagc cacttgagaa gatgccaagc gttcaatttc tctctcgttt aattcgaccc
     3301 cgtgagcaaa tacggacgga tgatctaaat aacccagttc ttcaagaaaa gcaagggggc
     3361 atttgccgta tcgtttgagg ataattcctg actcctcctt ggtctccgcc acatggacat
     3421 ggagcggaat atttagctct tttgccattt ccaaactcgc ttccagcaag tctctactgc
     3481 agctatacgg agaatgaggt gctaccataa ccttgaaatt tggattttta tattttaaga
     3541 tttcatctat gatggatcga gttctgctta tagtctcagc agttgtttct gtctctgaag
     3601 aaaagagagt cggagaaaaa taacaacgca tcttggaagt tttcaccacc tgataaattt
     3661 gctggatatc cacaccattg ggattataca tatcgttaaa ggttgttgtt cctgactgga
     3721 gcatctctgt tagggcttct ttaaccgcat tggtagtcat gtcgggagta aactcagatt
     3781 ctgctggcca gatatagtca ttgagccatt catggagatt gctgtcatct cggatccctc
     3841 tcagacctgt cattgcagaa tgggtgtgac aattgaccaa accaggcata atccaagctc
     3901 cctgatagtc tataatctgc tcagcttgtt ctaaaaacgc tggcttatct tgaccgacat
     3961 agacgatttg agaatccttg actgctaaga ttccatcaag ataaacatgg aaattttgat
     4021 cacaagtcac gatatttaca tgctgaaaga ctttcattat aggctccttt tctaaaagac
     4081 aagttgtact ctcttcaaac cacttcagat tcactttgcc gtaggtgtgg ttactgactt
     4141 cgtcagttct atctgcaacc tcaaaacagt gttttgagct gacttcgtca gttctatctg
     4201 caacctcaaa acagtgtttt gagctgactt cgtcagttct atctgcaacc tcaaaacagt
     4261 gttttgagct gacttcgtca gtcttatcta caacctcaaa gctgtgcttt gagcaaccta
     4321 cggctagctt cctagtttgc tctttgattt tcattgagta ttacagtgaa caatttttct
     4381 agctattgta acaaaaaagt cactcgaagg caactttttt cgtccataaa ctttcaaaag
     4441 agaatggctt attcagaact aaaagccgca gctttttgca tttggtaata cttacccttt
     4501 ctatccatga gttcttgatg gttaccatat tcaacaatat caccatctac taagacaaga
     4561 attaaatccg catcctgaat ggttgacaaa cggtgagcaa tgatgaagct tgtgcggccc
     4621 ttcatgagtt ttgcaaaggc atcctgtacc agcacttctg tccgtgtatc aatggaagaa
     4681 gttgcctcgt ctaagataag aatctttgga ataaccagaa agactcgggc tatggtcaag
     4741 agctgagctt ggccgacaga gagagattct ccagcatttt ccaacttggt atcgtatccc
     4801 tgtggcaact gttggatgaa aaagtctgca ttagctgctt tggcagcagc aattacttgc
     4861 tctcgactgg cttcaggatt gccaaaggca atattatcat gaatggtccc ttgtgtgagc
     4921 caggtttctt gaagcaccat accaaactgc tgtctcaatg atactcgtgt ataatcataa
     4981 atggattgcc catccagcaa gatatctccc gagctaatgg gataaaaacg cataaggaga
     5041 ttgataagag ttgattttcc agcacctgtc ggaccaacga tggctatctt actaccagct
     5101 ggaatatcga tagacaagtc cttaatcaaa attttttcag gatggtagcc aaaagagaca
     5161 tgtttaaagg aaatagctcc cttaacttgg tcactggtca agacttcctt acctgtttca
     5221 gccacttcag ggctatctaa gactccatag atacgctcta cgcaagccag agcactttgc
     5281 aactcagcta gcactgaaga aatatcatta aagggcttgg tgtattgctg aacatagttc
     5341 aaaaaagtca ctaaacgacc gacggtcaag gttgaaccca tcatgatacg ataagctcct
     5401 actccagcta aaagggcata aatgagtgca tttacaaagc gagtcgaagg attgaccgtt
     5461 gaagaataaa agatggctga ctgagaatag cctgagtagt tgtcatgagc ctcacgcaat
     5521 ctttggataa attctgtttg agcattgaag gactggatta tagtctgctg gctaagcgat
     5581 tcttcaatca actgagtctg aattcccctc gtctctgttt gcttctggaa gagatgatag
     5641 gatctcttgg caataaagcg tgaaatcacc atggacagtg gcgtcaacag caagactaag
     5701 agagtcatga ggagatgaat ttggagcatg gctagaatac taaccaaaat catcaaaaca
     5761 ccaatgaaaa attggttaaa aatcatggtc aagccagctg ccaactgttc gatgtccgtg
     5821 gttacacgac taaccatctc tccactacct tgcctatcta caaaagcaat cggtaaacga
     5881 tggagcttat ggatgattcg ctctcgcaaa tctctagtat aagagaagat tagacgatta
     5941 tagaggagag gattggccca ttgtaccaga gtatttccta ttaccaccaa gagcatctgg
     6001 agaaaaatct gccaaaaaac tggtgatgaa ccagccacta ggacttggtc aatgacctgc
     6061 ccaatcagaa taggtaggta aattgataag ccaacttggg caatagttcc tagaaaggct
     6121 aggaaaagga ggaagggatg gtttgctaaa tctacggcta aacgtttgag cgtctggttt
     6181 acagtttgtc gtttcattct agtcctcctt tccatgttgg gatgcattga tttcacgata
     6241 gacttggctg gatttcatca agtcatcgtg cttgccaaca gctagcaact cacctttttc
     6301 caagaggaga atctggtccg ccatctgtaa agttgaggtt cgttgagaga tcaaaattaa
     6361 gctcgtgttt ggaaaatttt ctctaatagc tttcaagagc ttggactctg taatggtatc
     6421 cagtgccgag gttgcatcat ctaggatgat aaacggagct tggcgcaaga ctgctcgggc
     6481 gatagacaac ctttgttttt gtccacctga gaaatttcgc ccccctgcct caactagggc
     6541 atccaaaagt ccttccttat cactgacaaa atccttagct tgcgcaatct ccaaggcctg
     6601 ccagagtttc tggtcagata cttcttgatt gaaacctaga gtcaagttgg aacgaatggt
     6661 tcctttaaag agttcgacct tttgaggtac ataggcaatc caagaccgcc actgctccaa
     6721 attaagagga ctacgtccat tttgataaag gtcaatgttc cccttgtcta ctggataaag
     6781 tccaagtaag agttgcacca agcttgattt accagaacca gtccccccaa tgataccaag
     6841 gatttgtcct tgagtcatat caaaggaaat gtctctcaga gaaggctggg ccgcatcagg
     6901 ataggtaaaa gtcaattctt ggacttgtaa aacccgacca ctggtaactt gcttttgttc
     6961 taattctgaa tggatgtttt cgggagattc cgcaaagacc tcctcgattc tcttggctga
     7021 gatataggac tggttgaggg aattgatcag catggcaagc ttgaccaatt ccaccaaaat
     7081 ctgtaagagg taattgataa gagcaatgag agcaccttga ctgagcactc ctccttgaat
     7141 tgaaatatag ccttgccaga taataacgag aagagttcca ttgacaatca gataggtcag
     7201 aggtgttaat aaactagacc agaaacctgt cttttcttgt aatctagcat aaacttggtt
     7261 aagggtttga aaaatctgta actctcgttt ttcttgacca aaagcacgaa taacccgcat
     7321 cccttgcaat tgctggcgcg tttcctgaac cagttggtcc gttttctttc tgagactact
     7381 gtagagagga ttgaccaatc gagatagccc tacaatgaca atggtcaaaa tggcaaccat
     7441 gactaagaac cagaaagtca actcagctga gattcgataa gccataaaaa tggcaccaaa
     7501 aacgataatg ggcgctcgca aaaagagacg caggaattga ttgataccag tctgaatctg
     7561 gtaggtatcc gaagtcaagc gagtgaccaa actagaagtt gtcagacggt ctctgctgtc
     7621 cttggacaag gaaagaatat gacgataaag atcgtttgtc aattccttag caaagcctac
     7681 tgctgccttt gctgagtaaa attgagctat caaggccact aaaacgccaa ttactgcaaa
     7741 gataaggagc aggccaatct gcatccagag atgaccttga tctccctgag gtaaagattg
     7801 gtcaacaatc ccagcaatca ccatgggaac caagagctca aaaacagctt ctaacagctt
     7861 gaacaagggg gctaaaattg attccttgat gtagggtttg aagtaagata ataggtgttt
     7921 cataaatccc ttctattcat attctagaaa tgaagaaagt gggaagcccc actctctgtt
     7981 ttatttgttt aagtaaggca atagatagcc atatcctgct ttttccatct catccttggc
     8041 cacaaagcgt aaagaagcag aattgataca gtaacggagg ccgcctaact cccgcggtcc
     8101 atctgtgaaa acatgaccca agtgagcact gcctgaacga gaacgaactt caattcgctc
     8161 cattccatgg ctcagatcct tgtaataatg aatcaactct ttggaaatcg gacggctaaa
     8221 acttggccaa ccacaacctg aagcaaactt atccttggca aaaaagagtg gctcacctgt
     8281 cgtaatatct acataaatcc cctcttcaaa ggtttggtca taggcattgg taaatggagc
     8341 ctctgtagca gcttcttgtg tgacacgata agactcttca gatagactgg ccttcaacac
     8401 ctcttgacta ggcttttcat agtttgctgc atcaatcaat ggcttatcag catcggtcac
     8461 atcgatatga cagtaacctg aaggattctt cctgagatag tcttggtggt agtcttcagc
     8521 cagaatgtag tggcgtaatt gctccacttc tactgcaatc tttcgaccca gcatgcgttc
     8581 ctgctcctgt accactgtgt agatagctgg caaatctgct tcatcctgat aataaatccc
     8641 agttcgatat tggcgaccac ggtcattccc ttgttgattg atagatagag gatcgataac
     8701 tcggaaataa taaagtaaaa tctctctgag tgacacttcc ttctcatcgt aaatcacttg
     8761 gaccgtttct gcatggtctg tttccttgat caactggtaa ttggtcgttt cgacttgacc
     8821 attagcgtag ccaacactgg tttctagcac tccagaaatg cgtgaaaaat attcctctag
     8881 gccccaaaaa caaccacctg ctagataaat ttctgccatc tttatttctc ctttatcacg
     8941 tttttaacta atactcttcg aaaatctctt caaaccacgt cagcgtcacc ttaccgtata
     9001 tatgttactg acttcgtcag ttctatctgc aacctcaaaa cagtgtcttg agctgacttc
     9061 ttcagttcta tccacaacct caaaacactg ttttgagcag cctgcggcta gcttcctagt
     9121 ttgctctttg attttcattg agtataaact tcttttcaca aaaaggatat gaaaccctct
     9181 ggtcaagagt ttccccatcc tatcttctat tctttatttt gcttctacac ggacaccttg
     9241 ggtatcaact ctcaagtcat gcagttttcc tttgaaaggt tgcttttcca attctgcctt
     9301 aattgttggc atcttgtcat gagaagccag aaccataact gtcggcccag caccagaaag
     9361 gtaggttgca taggccccat tttctttggt cacttgctta atcatcgcaa attctcttac
     9421 caagtcctga cgatagcgct catggaagag gtctccctcg attgcttgcc cagcggtcac
     9481 catgtctcct gccaacaagg cagcaaccgc tacattggcg atagaacttg cagcagcagc
     9541 ttccttataa gacaattttt taggcaagac actacggctg tcgcgagtac gtaattcata
     9601 gtttggaatg taagctagaa aatcacactc tggaaagtct gctacgatag cagagacttg
     9661 cccttcaaca gaacttgcaa taacgagatt accataaatg gctggagcca cattgtcagg
     9721 atgcccttca atcttggtcg ctaactgcaa tttttcatgg tctgataagt tgagttgacc
     9781 cagttggttg gctagttcaa tcccagcaac gataaccgag ctggaagaac ccaaaccgcg
     9841 cgccaaaggg acatcactgg tcattttcaa gcgtcttggt tgcaagtctg gtacaatttg
     9901 caaagcgatt ttgagcaaga gattacgctc atcatgtgga atccatttgc caatctggtg
     9961 ttcaatcagc cactcatctc gttcttcgca gacctcaatt tgaagatact tggttacagc
    10021 tacaccgacc gagtcaaaac ctggcccgat attggcactg gttgcaggta caataatctt
    10081 catcttattc tcctagcacc ttgaaggtat tcaagaggtc gaattctgaa accttcttca
    10141 attcagctga gacattttca agctgggctt tattaatctt gtgtgtgatg ataacgacac
    10201 gcgccttgtc accctctttg ccatcttgaa ggatttgctt aaaggaaata tcttgagcat
    10261 tgaagatttc agccaacttc aagacctgac cttttgagtc tggagccaag attgagaaat
    10321 agtagtttgc tttgacatct tcaggatttg ccaagaccaa gtcacggcta tattcgttga
    10381 agtctttgcc aatggtacca tcattcaaac gacgaacgat acggacaata tcagctacaa
    10441 cacttgttgc agttggtttt tgacccgcac ctggtccgta gtacatagac tcaccaatac
    10501 cgatagattc tacaaagaca gcgttcatta cgccattcac actagcaagt gggtgcgctt
    10561 tcggtaggaa ggttggagtc acttctgcag caatacctga agaagtttcc tcaatagaac
    10621 caaccaattt cactacgtaa ccaagctctt gagctacagc tacgtcttct ggtgtgatat
    10681 tgcggattcc cttgtgggct acatcatcaa aggcaatctt catgccaaag gcaaattggc
    10741 tcaaaataac catcttgtag gctgcatcaa tcccatctac gtcattcgtc ggatcgcttt
    10801 ctgcaaatcc tagacgttgt gcttccgcaa gagcatcatc gtaagaccag ccttcttcca
    10861 ccatcttggt caccatgaag ttggaagttc cgttgactac tccaagcacg cgcgtaattt
    10921 tatcagaagc caaggaattt gctaaagtac gaagaattgg aatcccacca gcaactgctg
    10981 cttcgtagta aagtgctacc ttgttagctt gagcgatttc tagcaattct gcgccatgga
    11041 cagctaaaag gtccttgtta gcagtaacaa cgtgttttcc agcttccaag gcacgagtga
    11101 taaaggtttt agcaggctca atacgcccca tcaattccac tacgatagta atatcctggt
    11161 ctgataaaat atcatccaca ttggttacaa agttaaagtc attccctgct gcaagcaagc
    11221 gatttttttc atcttcatcc ttgaccaata ccttagcaac tttgatatct gaatgtgctg
    11281 attgattgat ttttcctcca ttttccttta ggaggaaagg cacaccactt gcaacggtac
    11341 caaatcctag taaagcaatt ttaactgtca tctttatctc ctcgaaattt tctaatatag
    11401 ccattataac agaattttgt gaaaattcct attatagtaa atcactattt cagtataaaa
    11461 agaaaaaacg aatcagacga ttcgctcttc ttaaaatctg aaaatagctt tccagaaagg
    11521 attagccgat tttttgcaga ttgagcactg catcgtgact catcaagact tgaccatact
    11581 cttgtaagac tgagcgactg atatcactat cgtctgcaaa ctcgcgcata cgggccaaca
    11641 gccaagctgg atatgggctt ggatgatttt caatatccac taaaatggtc aaataatagc
    11701 gctcgttcat tttgtagagt tcagaagttt ccatttcaaa agtcactgtc ttggcaaaag
    11761 ctaccaagtc agccaactta gcaaaagaaa ggatgtagta gatgtaaggt tctttcttac
    11821 tctcagcttc ttgttcagcc tgctcttgct cttcttcctt ggcttcaact tgctcaagag
    11881 attgaatggc ttcgatatca tccttggttt tgtctgcgat gcttttttcc agggttttga
    11941 taaattcatc tggagacatt tgagccaatt cttccatatc tggcaaatcc gataagtctt
    12001 caaaatctag attttggtca atctttgact tggtcacaaa gacatctacc ttatcaggtt
    12061 ttggagtcac acggaagctc aacatgcctg tatccagaaa gctatcaggc atctctagct
    12121 catccaagat agcataaaag aactcttctg ttttttcttg aggaacgaga aagtcagcaa
    12181 tctccattcc acgatccatc aaatcctcta aagacatcgt gatttttaaa gttgtatcac
    12241 taatttgttt cattttcatt gctagtaacc tcatactttc agttctatct attatactag
    12301 atttttacga ttttatcaaa agaaggctcc tctatacgga tagattttcc ctagggtctt
    12361 tctataggag actccaagag aaaatttctg cagacagata gaaaaagcct tcaaaatcgg
    12421 ctcttagccg attttgaaga ccttatacat cagaatactt ataatttaaa ggttgctaca
    12481 ccgaggatag aacgatttaa gtttctgaga atttgaagac tttgctcaaa tttcttataa
    12541 cgagtcactc cgtactcttc aacaagaagg actgtatctc tttccaaaag agatgataca
    12601 tcctgcaaat ctacaaaatg cattcctttt aaagcttctt gactctgttt caatttatct
    12661 aggatagctt tatttgagct aacgatggtc aattcctgtc cagtattttt gtatgacaaa
    12721 acatctgcta ggttagcaat tgttgtaatc tctgttacaa aatcaatttg atactgagaa
    12781 aaatcaccta ctctattgat tgttggatta aagagataaa ctaacacatt tcccatcaca
    12841 accaaaatca cacaaaccac tccaataaca actaaacgaa gaatcagatt tttcacattt
    12901 aagccaagcg ctgtttcacc atttgcgttc aattctttag agttgatggt ttccagtttt
    12961 tcaattttca catttgcata agcatgttta aatttctcaa tcaacccatc aatttttttc
    13021 tctaacaagt cattggcatc tttacttgat gtcaaaattt tcacaccaac ccctgcatcg
    13081 tcaatcatat agtagacggt caattttttc caccaatagt cattcgttga atttttcaag
    13141 gttgtttccg tcgtgtctaa ttcactggca atttttttca actcactggg ttctacatca
    13201 ttgaaaagat aagctccatt caaattacca tcaatcaatt tcccataaaa atcactataa
    13261 ccaccaattt gatgattcaa aatcgttttg gccgaatctt ctggaggagt gattttatag
    13321 ataagataag ttgaataact tgttgtatct ttgacagtgt ttttattcct aactgcttta
    13381 attgtaaatg gtacagcaat gagagcaaat aaagcgatga gagctaaaat atttgctttt
    13441 cgttttttat aaagatttgc aaacaaatca gctactgaat aatgttcaaa catgattttt
    13501 ttctcctttg tttagtagat actagttttc ctttgtaagc atttttgcta caaatataat
    13561 cacaagaaca attccccaga attgcattgt aaataaattg aagaaacttt ctgaaaagct
    13621 gcttcttggc ataaagaata gattattcaa gatgagtagg gataaagcaa ataggattgt
    13681 ccttgagcga taggctactt gcagcatggc tataaataat acgccgagta agaaactaag
    13741 cagaaagact ccaatcatac catagtcggt atacaactcc atgatataac tacttccgat
    13801 accatgccct ttcaagtatt ccttgttcaa gacaagatag gatagattgt gggcataact
    13861 attactatca atagctagtt ccacactatt ggttgtatgt tcaaaggctt ttcctccgaa
    13921 aatggctccc aaactccccc ttgcaaaata atcaagaaca ggaccaaaag taaaattacg
    13981 gaaatctcgg taagggaggc tactgttaaa tagaaaacct cgagccagaa caccaaaact
    14041 agtcccttgt ttatagataa agtcaagtaa gatatcccag aaacctgtat gagaaacttg
    14101 gacattatcc cgtacataat tgagtactcc catcgctaac atgagaatag gagaacctac
    14161 aaaaatcgct aacttttctt taaacccaat ccattttcct ttttcagttt gctcccgcat
    14221 aaagtaataa acaaaagcaa ataaaatact taaaataaag ggatttcgtg tcccaattgc
    14281 caaatgaata gtattagctg caataaagga gacaagcact gctgtggcct gcaatttctt
    14341 tggcttggtt gccagataca tacacattgc atagaccgta aaggtagaca aaatgtaggt
    14401 aaaataaggc agtttacttt caaaatttgc atagtaggca tagtaggaag tctgcaaacg
    14461 atacaagagc cgttcaaata accgaatgaa atagaaagga taggttagaa gaaaaactcc
    14521 tagtgataca aagcgtaacc gcttgatata aacctctttt agagaatttc ctatatttgc
    14581 tacttttatt ttcttcctag ctatgaagta acgagccaga atgcctcctg tggtcaagcc
    14641 cagaatcgaa accatgacaa ctataaaggc aaaacgatag gctattggat gataggtatc
    14701 caaagcacca tccctaaaat aatcaatggt cggtcttgat accagaaata caaaaatggt
    14761 taaatagaaa ataaaatgga ttaagtaata cttgatatca ttccaacaag caattaagct
    14821 actaaccaac aagaacaata aagtagaaag taagctaaca ttattattat tattaaacag
    14881 atacacaatt ccacttacta gcgtcaaggc ataactgact atggtcaaac taaataataa
    14941 tcgtttccca tcaatcactt ggtcaccccc gttctaatgt aattttttag atttttcaat
    15001 atttttcagt aataagaatc gatataagga aatatttatg aatagggcca aagcactaat
    15061 tcttctcccc ttacggaaaa ttggattcct agaaatagca aaggcatggc cttttaaaaa
    15121 acgatgaatc tgagaatagg cttcaaactg tttatactga tcatctagca acatcttatc
    15181 cagaataaag aagtgggcat aggccaatct gaaaaaagcg acctctttca agtcaggata
    15241 gtttttcaca acttcattat aaaacttttg gtagatatca atataggcta aatccttctc
    15301 tgcatagggt ttggtcgtaa tactatcccc tctatggaaa tagtaataat agggtttagt
    15361 attaaccaca tacttcttgg ccaacttgat taaatcaaaa tggtaatagg catcttcgta
    15421 aatcaacccc ttaggaaagg atagggcagt tgcaatctgt ctcttgatta gcttattgca
    15481 aatcgtccca ggtatttttt cacctatgag gtattccttt agaaatgttt gagaatcaca
    15541 gacaaaatag tcatcctgat tggctgactg tgggctttca tcattagcat agacattcat
    15601 gacaccacag cttgaaacat ccgcatcttc ttgaactaat tgctcatata agctctgaat
    15661 catttctgga tggatataat catctgagtc aataaaaatc agataatccc cgtgagcctg
    15721 cttcatccca tcatttcgtg cttgcgacaa tccttcgttc tttttatgaa gcactgacac
    15781 cctgtcatct tgttcagcga ttgaatcaca caagcgacca ctttcatctg ttgcaccatc
    15841 atcaacaaga ataatttcca gattttgata ggtctgcttc tgaatggaag ctatcgattt
    15901 ttctaggtac tgcgccacat tatagactgg cacaatcaca ctaattaatg cagtttccat
    15961 gctactcctc taatagtttt tctacttgtt cgatttgttt tgtaattgta aattgttgaa
    16021 tgaattggct agcctcatcg acatcaaagt ttgaggcaga agtcatgtaa ttagtaatcg
    16081 cctgagctgc ctcttgattg ctctcaatga tttgtccaaa tcgtccttct tgggataatt
    16141 cctcagcccc tccaacgtcc gtagagataa aagggagtcc cagactcaag gcctccacat
    16201 acactccagg aaaaccttct tgtttagaca tagacaagag aactttcgtc tgagatagat
    16261 actgataagg atttttttga taaccaagga aatgtacata gtcctcaatc ccatactctt
    16321 tgactcgttt tttcagttcc tcttccatat caccagcccc gataaaatag agatgatagt
    16381 tttttccctc ttggtgtaat aatcgtatca cttccactac acggtcagaa cccttatttt
    16441 cctcaatccg tccgatagta cagatacttt gaggagcaat ctcgatatcg atcttctctt
    16501 gagatttttc tagaatagtc tgaaaatcat atccattgta gattgtctgt aatttagaag
    16561 cataatctgg ataaacttcc ttgatagaat tgctggtctt ttttgaaatc cctacaattg
    16621 tattcgcagc atccaactgg cttctatgtg attctctttt agagctatcc ttaagaagtt
    16681 cttcaatact tccatgaatc caagatatct tcttgacttc tcttctttta gagaacaaca
    16741 gtggtggatt cataatggta aaagaaactt caacatcata atcatctttt acaagcaaac
    16801 gacgagccag tcttggaaaa taaattctca ttctccacaa aaaagctcgt aaccatctgg
    16861 tttggcgata atcttgaagg gattttaaaa tgcgtacatg ctttggaaca gattcatatc
    16921 ccttgtcaaa gtgctccatt tcaagaatat caatatcata cttttctaga tccagatttg
    16981 aaacaatggt tgatagaatc ttctctgcac cacctccaag agaaaaagac cacataaaaa
    17041 ataagatttt tttcttagcc accatattct cccttgtatt ctgtataaga cttatccata
    17101 tcagcgatga cagcatcatg atgcggtacc tgcttgtctg ctggtggagg cgtcatataa
    17161 tccccaaaag cagttctgag atagacatca tagccgattg gaataggcat ctctgttcct
    17221 tcaaatggca agaaaagatt gtcttcaaaa gatgtgattg ggtacttgtt tctcatgtag
    17281 ccaggacctg agcataattc tgtaatgcca tcacaatcag ccaaatcata cttagtcatt
    17341 tctttctcag cttttttcca gatgcgataa cggagagatt ttggagtcaa acccagtaaa
    17401 atgcgacttc cccatttcat gagagcacca tgcttttctg gaatagtttg cgcacaaaag
    17461 agtgaataaa tcaaggccca acgaacctgt tttttccgct cagctggatc tttcggataa
    17521 taatccaaag gcaaaacatc caaggccaga ccatgtggca aatccaaatc ctgctgataa
    17581 ggcttgatac aggtggtttc cttgtcacga atggtaataa aaagattacg atcaacaaaa
    17641 tccttgtaac tctttgacaa gaaataacgt tcatctgcat aacgaggcca taattctgct
    17701 aatttctcat aatctttacg aggcataaaa aagtctaggt cgtcgtccca aggaataaat
    17761 cccttgtttc gaagggtacc aatagcgcct ccgccacaga gataacagag caaatcatgt
    17821 tctttacaaa aggccacaaa atagtcagcc atctccagac tacgagcctg aattgctttt
    17881 aaatcagtca tattgttcat tattctttct atcgtatcgt ttcattatac cacaaacaag
    17941 gggtgaaaat ctattgcaga ctgtaaaaaa tcaaagcctg actgctatcc aaatagctat
    18001 caaactttga tttttctgtc ttatactctt cgaaaatctc ttcaaaccac gtcagcttca
    18061 ccttgccgta ggtataggta actgacttcg tcagtcttat ctacaacctc aaaactgtgt
    18121 ttttagcagc ctgcggctag cttcctagtt tgcactttaa ttttcattga gtattatctt
    18181 atctcaagcc catttgagcg agcttggttt gatatttgtt ttgatcaacc agcaagccca
    18241 agcctccata aacatcatag gcatctaccc agtcacccag ttctggaatc gtcaattttt
    18301 caataccatt ttttgctcca tccaaaacag ataaaccgtt tgttaggagg aaagtatagg
    18361 gtacgttggt tgaggtcata gcaaaaacct ttccaagagc ttcagaacca gtgaaaagtt
    18421 tagtgggatc tttaatttgc tctaaaattg ctgttaaaac ttgttgctgt ctttttgtac
    18481 ggccgtaatc cgcctcatca tcatcacgga aacgagcata attgagcagg gtcgagccat
    18541 tcatctgctg ttttccgact ttaatggttt gggttggaga ctcagtctcg gtagcatata
    18601 aatcatctcc gactgtagct tctgttaggg gacgcccatt caatgttgaa aattgagcat
    18661 caatcgtcac cccatcaggg aaaagcgtgt caatcgctgt ggcaaaggcc tggaaatcaa
    18721 ccaaggcgta gtacttaatg tccaagtcaa aattatcttt caagacttgg cgaaccattt
    18781 ctgccccttt ttgcccctct tgttctccta actcgtaggc tacgtttaac ttgttatctg
    18841 tctgttttct accattaatc acttgactat aaccatctat atagaccaaa ttatcacgca
    18901 tgaaactgac tagcttcatt ttcttatctg agcccccgac atttaatacc ataatagagt
    18961 cagttcgtgt ctcaacactg ttctggccga ttcgaccatc agtacccatg attaaaatat
    19021 taactccatc tctagtgtcc tgaccattaa atacttctac ttgagctgcc cgggcatcag
    19081 cagttttctt tgcgctagca tcttggtaac cacgcaaaaa catgaatacc atggccaaag
    19141 ccacacagac caaaagtgaa aaaatcacca taaaaattcg tttaagacgg agcttccgtc
    19201 ttttcttttt tggagggaaa gagagtgctt gtgatttgga ttgtgagcga ctccggttcg
    19261 catagcttgg taagtcaacc tgctcttctc tttcttgttc caagctagag ctactatttc
    19321 ccctagcaag agttagcttt tcttgcaaat aggcaaactc atttttttct ctctcattga
    19381 gatagtgaat attttttagc aaataatcat aacgcaactg ctcatgatga cttaagggat
    19441 tttctttact catcttctct cctttccatg gtctgatatt ggataaatag gataggcacc
    19501 cagaatttta tactggattc caatcgcttc taattctttt tgggcaaagt ggaccaagtc
    19561 cttatcggta taatccacat cgataatgaa aaagtattca cccagtgctg tcttgagtgg
    19621 acgactttca atttttgtca agtcaattcc tcgccaagca aaggtcgaca gggctttata
    19681 aagtgcacct ggaaggttgt caggtagggt caaggctaaa ctcatttttt cagtttgtga
    19741 ttgcaaggga atagttacac cttcagctcc caaaacccaa aaacgtgtga aattggcttc
    19801 catttcctga atatcctcgg caatcagttc caatccatat tcttcagcag aacttctagg
    19861 tgcaactgct gcaaagggct gatctggatg ttcggaaata aaacgggccg cataagctgt
    19921 actagctgtt acctcgattt gagcctctgg atattgttca tcgatgaatt tctttccttg
    19981 agccaaggcc tgtggatgtg aaaaaatctt ttcaatctta gtatggcctg gaaccaccat
    20041 caactgctga tgaataggct gaacgatttc tgctactgct tggatgtgag cctgatgaaa
    20101 aagatagtcc aaggtttcat gaacactacc ctcaatagaa ttttcaactg gcaccacaga
    20161 atagttcact aatccttgct cataagcctt gatgacatct gtaatgttgg caaaagcctg
    20221 caattcctca tgaggaaaag ctgtctgcac aacgtggtgt gaaaatgatc ccttgggacc
    20281 tagataagct attttcatct tagttcctct ataatttcct ctgggcttag cttggtcaca
    20341 tccaaaaccc gactagccac ttcctcatac caagcctgtc tttcttgaaa aatagctact
    20401 agttcttcct tgctattatt tagaaaaagc ggtcgctgat tgtccttatc agctgcgata
    20461 cgtaggtaga gggtttcaaa atctgctttc aggtagatgt tatctgtatt agtcttgagt
    20521 aagtcacgat ttctctgaga aataaccact cctcctccag ttgacacgac ttggtctgtt
    20581 tgtagtaaat cagctaggac ttctgattct acctgacgaa aggctgcttc tcccttttca
    20641 gcgaaaaaat tcgcaatgga catacctagg cgcttctcaa tcagagcatc catatcaagg
    20701 taattagggt ccaagcctct tgcaatagtc gattttccag cccccataaa ccctaataac
    20761 accttagcca tgaatcaagc tctccaaatc atcaaagaaa ctaggatagc tggtattgat
    20821 ggcttctgca cggtcaagct ccacctctcc atctgcaacc aagagggctg cgatagctgt
    20881 catcatgccg atacggtggt caccaaacgt attgactcta gcaccgtgaa gagctgattt
    20941 ccctttgata atcatcccat ctgccgtagg agtaatatct gctcccatac tatttaaggc
    21001 gtctgccaca acctgaatac ggtctgtttc cttgaccttg agctcctcag catccttgat
    21061 aactgttaca ccttgggctt gagtcgcaag cagggcaata atgggcaatt catcaatcaa
    21121 tcgtggaatc aaagcgccac caatctctgt tcctttcaag tcagaagact caacaatcaa
    21181 ggtagcagat ttagcgactg gatcgatttc agttatttcc aattttccac ccatggcacg
    21241 aatgacatca ataataccgg tgcgagtttc gttgatcccc acattctgca gcactaaacg
    21301 agaatttggg acaatcaaac ctgcgactaa ccaaaaggat gcactggaaa tatctcctgg
    21361 tacgaccacc ttttgtccag tcagtttttg aggtccttga actgtgattt tcttgccatc
    21421 cacacttaaa tggccaccaa attgttgcaa catatcttca gtatgattac gggtgcactc
    21481 tttttcgata ataactgact cccccttagc ttgtaaggct gcaaacatca aggctgactt
    21541 gacttgggca gaggcaattg gcaactcata atgaataggt cttaggtttt tcgtcccttt
    21601 taagcgaagg ggaggcaagt ctcgttcagt ttgccctgag atgctgacgc ccattttttt
    21661 cagtggaagg gtcacacggt ccataggacg tttggaaaga ctatcatctc caaacatctc
    21721 tacttcgaaa tctgcaccag caaggacacc tgaaatcagg cgaatcgagg tgccagaatt
    21781 tcccatatta agggcatttt gcggcgcttt taagccagcc atgcctacac cttgaatggt
    21841 aataacccca tctttatcct caatttcaac accaaggtca cgaaaaacct gcatggtcga
    21901 aagaacgtct tcacctcgca gaatatcata aaccttggtc tcaccctcag ccaaacttcc
    21961 aaagataatg gaacggtggc tgatagactt gtcacctggg acgcggatac taccatgtaa
    22021 atggcgaata tttgttttta gtttcatact ggacctcata cttgcaatac ttttacctat
    22081 tttatcataa aaagccagaa attccttaaa aattcctgac tttaggatag ttcttttctt
    22141 atttcagcaa ttctgaaact ggttcgaaaa caattttttc aatgtcagaa aggtaaatgg
    22201 ccaattgttg ttgcttggta aagaattctg acaagaggct atttccttga atctgtttac
    22261 caaagccttc catcttagct tggaaggacg catctggcat ttgacctgtc tgtgctagtt
    22321 tttgaatttc ctcttgaaag gcaagatatt ctgtaaagat tttgcttgcc tcagcatctg
    22381 ctgcaatcgc atctttagct gctttaacag ccttgtattc tggtaatccg cgtagaccgc
    22441 gactgagttc gtttgcacta tcgtaaatat ttgacatgtt cttctcctta tttaatgacg
    22501 actgtatagt cggtattttt tgttatgaga tgctcggctc tttccaagtc ttgagcattt
    22561 ttaaatgaaa tttgtaggat tccgtgaata tcctcacgat tttcctcgtt gatgtggatg
    22621 ttaaccaagg aagtcccacg tagcagttcc aaaatccgca ggatgacatc ttcttcatca
    22681 ggaacgtcaa catagaggtc gtaagagcta tccacaccac cacgcttatg gatttccatg
    22741 gtctggcgtt gttcacgcgc ttggttaaaa aagttccaaa tttgctcttc atctccctta
    22801 ctaatggcct gaccaatcga ttccaaacgt tccttgaaat cctcaattct atccagaatg
    22861 gtctcgctat tggacaagag aatggaggtc cacattcctg gctcgctttc cgcaattcgg
    22921 gtcatatctc gaaaaccacc tgccgcaaag cgccttgcca tctcatgctc ttgagcatag
    22981 accgcagtct gctccatgag actagaagcc aaaatatgag gaaaatggct aatctgagaa
    23041 gtgacacgat catgctcctt ggcatcaatc tcgataaaac gagcatgaag acctgaaagc
    23101 agatccttca tttccttaag cgtgtcctga cttgtcaggc ttgaaggtgt aaagatataa
    23161 taggcatttt caaaaagatt gacatctgcc gaagcagccc ctgtcttgtg actaccagcc
    23221 atgggatggg ccccgacaaa gcgaacagac ttgccagcca aatactgctc cgccgcatcc
    23281 acaatggttg acttggtcga accagcatct gaaataataa cgccttctcg caaatccaaa
    23341 ttggccaact ccttaatgaa agcaatagtt tgtttgattg gcaagctgag gataatgaca
    23401 tctgccaaag gagcaaaact agcaaaatca tccgttgcac ggtcaatcat gccttctttc
    23461 aaggcgatat ctctcgaagc ttgactacga ttataaccta aaatttcata atctggatga
    23521 tcgcgtttga taccaagtgc catagaggct ccaatcaacc caagacctgc gatatagatt
    23581 gtttttgcca taggaactcc ttaatagttc tttgtatagt ctcggtgttt ggctaccgct
    23641 tcttttagtt cctcaagatt atctgatgag aatttttcga ggatctcttg cgccagaacc
    23701 gttgctacaa ctgcttccat gaccattcct gcagctggaa gagcagtcgg atcacttctc
    23761 tccacggttg ccttgtaagg ttcgtgggtt tcgatatcca cactcataag aggtttataa
    23821 agagtaggaa tgggtttcat gaccccacga acaacgatgg gttgcccatt agtcatacca
    23881 ccttcaaaac cacctagatt attggtacgg cgagtataac cgtcttcttt agaccagaga
    23941 atttcatcca taacttggct gcctttacga taaccagcct caaagccaag accaaattcc
    24001 acccctttaa aggcattgat agagacaaca gcttgagcca atcttgcatc caattttcta
    24061 tcccattgga cataggaacc aagaccaact ggaactcctc cgacgactgt ctccacaacc
    24121 ccaccgatgg tatcaccatc acgtttgatt tggtcaatat agtccttgat ttcctgttct
    24181 cgttcttggt tgacaataga aacttcagac tgggcagctc tttgcttaat ttcagcgact
    24241 gtcagatttt caggaacatc tatttcctta ccaccaaaga ccacgacatg gttggcaatc
    24301 tccatatcca gctcagccaa gaggcgtttg gctactgcac caactgccac ccgcatggtg
    24361 gtttcacgag ctgatgaacg ctccaaagaa tttcgcaaat catcaaaacg gtacttaatc
    24421 cccccaacca aatcggcatg acctgggcga ggatgagtaa ttttccgctt gcttttaagg
    24481 cggtcttcaa tgtcctccgc agacatgatg tccagccatt tctggtggtc cttattgatg
    24541 acatccatag taataggcgc ccctgtcgtc ttcccgtggc gaacacccga agtaaagaca
    24601 acctggtcac tctcaatctt catacgacca ccacgaccgt agccaccctg acggcgtcta
    24661 agatcctcat tgatatcctc agctgtcaat ggaagtccag ctggaattcc ctcaataata
    24721 gctgttagac gggggccgtg tgattctcct gcagttaaat atctcataca ctctccttat
    24781 tttaccaagt agtctttcat ctcttccaga gaaactgggt gaatggtcgc tgaaccaagc
    24841 tctggcacca agaccaattt caaggtgtta ccacgcgctt tcttgtcatg agtaagagcc
    24901 tgataaagct tgtcaacttt ccaattttca tagtcaacag gcaagccgaa tttctgacac
    24961 atctctgtga tagattgggt aatgccagct ggcatgaggc ctttttcctc agcaaccttg
    25021 gaaatctgta ccattcccat ggcaacagcc tctccatgca tgaccttgcc ataaccggca
    25081 gtcgcttcga tggcatggcc aatagtgtgg ccaaaattga ggtaaagacg aataccattg
    25141 tccaactcat cttcaaccac catcttgcgc ttcacctgac aagaatgttc aatcaaggtc
    25201 tctgcatgtt ccaaaatact ctcaacagaa ccattcagtc ccgtcaagag agcccacagt
    25261 tctggatcct caatcaagcc atacttgata acttcaccca tcccttcaat caactctctt
    25321 tttccgaggg tttcaagaac aagtggatca atcagaaccc catctggttg ggcaaaggtc
    25381 cccaccatat ttttagcaaa tggtgtgtta acgcctgtct ttccaccgat agaagaatca
    25441 acctgagctg tcaaactagt cggaatctga acaaagtgaa taccccgcat ataggtagag
    25501 gctacaaatc cagccaggtc cccaacaacg ccaccaccaa gagcaacgat tccatcgcta
    25561 cgagtcagac cttgcttgac tagaaattca tagactttct gaacagtagt taaattcttt
    25621 ctttcttcac cttctaagaa atcaaaaaca gctacctgaa aaccagcatc ttctaggctg
    25681 agcttgacct tctctgcata gagagaggct acatggttat ctgtcacaat gactaccttt
    25741 tgcggttgcc agagttctcg caaccactga ccagcctggg ccatacaacc tttttcaatc
    25801 tgaatatcat aaggatgatg aggaatatcg attctgattt tcataggaga gtctcccttt
    25861 ctttattggt atttttctgt taaagactgc caaatctctt ctgtcggcat ttccttgcct
    25921 gtccacagtt gaaaagcttc tgcagcttga tagagcaaca ttcccagacc attgactgct
    25981 ggattgccct gacttctagc ccatttcaaa aacggtgttt caaagggttg gtatatgata
    26041 tctgcaacta agagagtttc tggtaagact atgttttcag gaacaggaga ggattggcca
    26101 tccatgccca cactggtggc attaactagc aaatccgact cggcaatcct tgcttgcagt
    26161 tcagaaacat attctaaagc acacaaatcc actttaaaac ctgtctgctc ctgtaacttg
    26221 tctaggtaag gtcttgtttt ttccatagaa acggaacgaa caaagaccga aatctgactg
    26281 acgccatcca aaatagcctg tgccaagatt gatttagccg caccacctgc acccagcagg
    26341 gtcatctttt tacctgaaat tgtaaaagaa ggcaagcact taaaaaatcc cttgccatct
    26401 gtattatatc caattaaatt gccattctca ttgacaaccg tattaaccgc accaatcaag
    26461 tgcgcttcat cgctcagctt atccaaataa ggaatcacct gctccttata gggcatggac
    26521 agattgatgc caaacatctg gtagcgacga atattggcca ctgtttctgc caagtcactc
    26581 gcttcaatct cccaagccac ataagcaccg ttggtagctg tcgcctcaaa ggctctattg
    26641 tggatgaagg gagaaataga atgcttaata ggattggcaa caactgcagc taaacgtgta
    26701 tagccatcaa gcttcatcca aaatctccct gatttttttc atgctagcta gagaaatctg
    26761 cccaggggca ctaacctcat ccagactggc aaaagaccaa ctcgaaccag tcacatccgc
    26821 agtgatacga gagaccttgc ccaccttacc catagaaatg gtcacatatt cctgttcagg
    26881 attgagggtt ttaaagcctc gtgtatagtt catcaagtct aagacatcct gctccgtgtg
    26941 agccatcacc gcaaccttaa caagttttgg atttaggatc gtcaactctg acaagatttc
    27001 catcatgttc tcaggtgttt cttggaaatt atggtaactc aaaacaagat ttgggaagtc
    27061 cagcatttcc tcaaaaacat ccttgtagct atagtactca aaatcaatat agtctggttg
    27121 atagagttgc gcaacttcct tgattagatg gatatactct tctggagaaa ggtcgatttc
    27181 tccaccttcg gagcgagttc gtagcgtgaa aaccaactca cggcctgcga atttttcaaa
    27241 aatggctgga gctacctgca aaatcgcttc tttaggcaga tagtcggcac gccattcaat
    27301 gatgtcggca tccaggtacc tcgtggcatc cagagcctga gcctcctcta aacttcttgg
    27361 cattactgaa acgattaatt tcatttacta accttcatac taatcacctt gaggtaatta
    27421 ctactttcat cttttttatt ataggcaaaa tctgctggaa gaccatattt gtttaaaatc
    27481 tggtaacttc ttcctgcaaa acctttatca atttgttctg taaatttctg acgggaaaca
    27541 ttggcagcat tggtactggc aatgataatc cctcccggat ttaaaatctc aagactctgg
    27601 gaaatcaact tgtgataatc cttggccaca gagaaagttt gttttttatt ccgagcaaag
    27661 ctaggcggat ctaggacaat cacatcgtag gtcaagtctt tgcgtttggc atatttgaaa
    27721 tactcaaaga catccatgac tataaaacga tgctcgtctg tgctgagccc atttgcctga
    27781 aaatgcgctt gagacaattc tcgtgaacgt ttggctagat caacagaagt tgtctggcta
    27841 gctcctccca tggccgcagc tactgaaaaa gccgctgtgt aggaaaacat attgagcaag
    27901 gatttaccca tagccaagcc gtcaactaaa ctaccgcgaa cctcatgctg gtctaggaaa
    27961 attcctgtca tcaagccatc attcataaag acttgataca ggacaccatt ttctaaaaca
    28021 gtgaaaaagt caggtgcttc ttgaccataa acatgggcag attcatagtc caaaccctta
    28081 aagcggattt tctcataagc tcctaaaacc tcagggaaaa cctgtctaaa ggcttctgat
    28141 atagtctgac gaatctgata aacataagag ttataccaag aaaagacggc gtagtcgcca
    28201 taaaggtcca ctgtcagacc cccaaagcca tctccctctt gattaaagag acgaaaggca
    28261 gttgtcaaat catcttgata gtaggcgttt ctcttttctt tggcttttct aaacaacgtt
    28321 tcaaagaaag cttgattgaa ggccaccttg tctttgctga taaaccagcc caagcccttg
    28381 ttttgctgag aaaggtaggc agtcccaaga aagtttcctt cctgaccctg cacctctact
    28441 tcctgatcct taagattgac attctcaaga tcactggctt ctagtaaaac tagcccctta
    28501 gcaagcttct tttcaaccct tttgctgact cttattctat tcataactac cattatatca
    28561 aacttttaga caattctcaa aaaagaaact acccttgctt ttttactctt cttttaaaaa
    28621 atggtatact agacttcctg caaaactagg aagtaaatgt gtaagaatca cagtaaaaaa
    28681 tgctcttccg tcttggagga gcatttcttt ttatcaacga aaatcaaata gcaaactatg
    28741 aaactagcct caggttaacc gtgagattat aggtagagag gttgtatcag caatatgtgt
    28801 ctgtcaaatt tagtgacaaa ggtagtagaa gaaagatgaa gaaataaatc agcttcagta
    28861 gatatctgga aaatttgatt ttatagaaaa gccttttgtt acaaactcaa tatactatca
    28921 ataaataata ttatagaagc aacaataatt aaaatttcac ctatttgcat cattctattt
    28981 cgaactctaa atatatgttc tatcaaaaat acttggatca cacacattat aggaattaac
    29041 gtttttgaaa ttgaaaaata tcccaataaa taaactataa acaacaataa tagaactata
    29101 ttatatttct tattcaaaac attcctccct atatttttga ttaccaatct taatcattta
    29161 caactacatt ctaacaaact ataaaagcgt ttgtcgaatt gaatttatca agcaagcaac
    29221 caaccagctc atcttttttc tatttctgcc aatatgcgtg acaggtaata atgatagcca
    29281 aaaatagcaa gagcaagcaa gacgataaga gctcctactc ccaagttgat ggcaaggata
    29341 ggggagagag actgaaccaa gaatatgctc ccaattacaa gggccatcag gattgcacta
    29401 taaataaaca ataaaactat ggcgactatg ccatttgaac gattcaccag gtccgtaatg
    29461 ctactccaat tggttgacag atttttaacg tccttaaagt aatggtggca agaaaggatg
    29521 acactggcaa ggatccatgc cacaataagg taaatcatcg aaatgatggg caagcctaga
    29581 tatagagaaa gaccaagcaa agtcagaact ggtaaaaagg actggacagc atatataatc
    29641 caaaatttca ctttcacata acgagcaaag tcaaagggta aactcttaag aaaatcaaca
    29701 ttttccctct ccaaggacaa ggcaattgaa tgcaggctgg tgatattgtt attgacaact
    29761 gctataaaca ctcctacaaa aaacaagggt aaccagtatg gaggatgaat gtctggaact
    29821 atctgagaat ctcggatttt ggaaatcaga ccgatcatca tgagataagg aaagaaagca
    29881 cttgtaaaaa gcactgtaac cacgccagta ccctgtccca agagggtgag gtggtagcgt
    29941 aaaaccatgc ggaaaaatcc ctttttagtg gttgaaattc tctccttgct gcgacgttct
    30001 tttttgacct tctcctcact attaagcagg atcacgtcat aaaaacgagg aaggaccttc
    30061 tttttggtca gataaagcag gaagagagtt agtcctatcc aagcgagcag acccaatatg
    30121 gcttctgtcg aaaaaggatc cactgctatt ttgtaaaaga tatgaagagg ataaaggaga
    30181 aatggaatgt ctctaacttt gtcaacaata cttccaaaag tcgactgaag aaagaagata
    30241 aatattaaag gtatgagaac tcctatccca atcatcacat tcgaaaaaat agactgatac
    30301 tttctgaaga ccctagtttg agccaagaaa tgcactgcca ctaccatcac tagagccaca
    30361 gagacaaata ataaggtcaa ggacagtagc atcaaaggca aacccagcca tagagaagga
    30421 gctagcctaa tgtagaggac cagaaaataa gctaggattg gtacaattcc agttagagct
    30481 ggcaaaagga cagacagtcc tttagcaatt ataatctctg attctttaaa ggcatagggc
    30541 ctatacgata tcaaatcctt actctcataa aagacattgt aaaaggccgt taaagaagtt
    30601 gaaaaggcaa tcactagtaa aatagcaatc atcaagctaa aataaatagg tatttcctca
    30661 aaaggaaaat gaatggctat attactaaaa cagatgatca tcaagagact ggaaaaaatg
    30721 taagaactta agactctagc ggaaacattt acttttttcc caggattctt agcctgcttc
    30781 tttcgtagat tagccagatt agcttcttga gatgaataaa ggatattgat atcaactaat
    30841 tttttaatga ccttgagacg catccgcaac ctcctctttt ctaccagcaa gactaaggta
    30901 gatactttcc aaagactggt ctgggtaatc ttttctcaag tcctctacac taccacaata
    30961 aatcaaatgc ccctttttca aaatggcaat ccgatcacag acttgctctg ccacctctag
    31021 gacatgagtt gaaaacaaga ctgtcttccc tttttgtgca tgttccttca tcatctgttt
    31081 caaatcaaag gcagcctggg gatccaaacc agtcaagggt tcatccaaga cccaaatatc
    31141 gggatcagac aagagtgctc cgatgacaaa gactttctga cgcattccgt gagaaagagt
    31201 ttcaataacc tgatagcgat tttcagcaaa atcaaaaacg ttcaatagcc tagctagact
    31261 agcctccaag tcagatctac tcagatcata ggatgaggcg atcaattccc aaaattcatt
    31321 ggccgttaag cgtaaaaata agtcaggcga gtctgctacg tagccaatct ttcgtttaat
    31381 agccaagcga ttttccgata actcctgacc gtctaccaaa atacgaccac tgctgggtga
    31441 aatgatactg actagggatt ttatagtggt cgattttcca gccccattat gaccaatcaa
    31501 gcccataatc tctccatttt caatctgcaa attgagatta ctcaaggcct ttttatcacc
    31561 atacaactta ctaacatttt gaaattcaat catgggacaa ctcctatctt tatctgtatt
    31621 atatatcgct atactagcac tttgatacaa aaaaatcaat actttatttt aagtagttaa
    31681 aatagtttcc ttctatctta cgcaaacgtt tgcgctaata gatactttat gatagaataa
    31741 agaacaagat tgacaagtaa gaggaaacat tatgcaaaat caaacactca tgcaatactt
    31801 tgaatggtat ctgccccacg acggtcaaca ctggacgcgt ctggctgaaa atgctccaca
    31861 cctagctcat ctggggatca gtcacgtctg gatgccacca gccttcaagg caaccaacga
    31921 aaaagatgtc ggctatgggg tctatgactt atttgactta ggagagttca accaaaaagg
    31981 gactgtccgc accaagtatg gtttcaaaga agactatctt caagccattc aagcccttaa
    32041 agcgcaggga attcaaccta tggccgatgt ggttctcaac cacaaggctg ctgctgatca
    32101 cagggaagcc tttcaagtta ttgaagtgga tcctgtagac cgtacagttg aacttggaga
    32161 acccttcacc atcaatggct ggactagttt taccttcgat ggtcgccaag atacctacaa
    32221 tgacttccac tggcactggt accacttcac aggtacagac tatgatgcca aacgccgtaa
    32281 gtctgggatt tatctgatcc aaggggacaa caagggctgg gctaacgagg aattggtcga
    32341 taacgaaaac ggaaactacg actacctcat gtatgccgac ctagacttta aacatcctga
    32401 agtcatccaa aacatctatg actgggctga ttggttcatg gaaacgactg gtgtagctgg
    32461 tttccgtttg gatgccgtta agcatattga ctctttcttt atgcgcaact tcatccgcga
    32521 tatgaaggaa aaatacggtg acgatttcta tgtttttggt gaattttgga acccagacaa
    32581 ggaagccaat ctggactatc tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg
    32641 tctccatcag aatctctttg aagccagtca agctggcgca aactatgacc ttcgtggcat
    32701 tttcacagat agcctggttg aactcaagcc tgacaaggct gtgacttttg tcgacaacca
    32761 cgatacccaa cgaggacaag cccttgagtc taccgttgaa gaatggttca agccagcagc
    32821 ctatgccctc attttgttac gccaagacgg ccttccatgt gtcttttacg gagactacta
    32881 tgggatttca ggccagtatg ctcaagaaga tttcaaagaa atccttgacc gcctcctagc
    32941 catccgaaaa gatttggcct atggagaaca aaatgactac tttgaccatg ctaactgtat
    33001 cggttgggta cgttcaggtg ctgaaaatca atccccaatc gcagtcctta tctcaaatga
    33061 ccaagaaaac agcaagtcaa tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga
    33121 tttacttggt aaccaccaag gtcaagttac aattgatgag gaaggttatg gacaattccc
    33181 tgtctcagct agatccgtaa gtgtctgggc agtcaatacc atctaatagc tcataataac
    33241 caagctaggt ccaagcggat ttggcttttt tgtattcaca aaaagaccta cccaaatgga
    33301 tagatcttta cttgattaca atttacctgc tactgcatcc aacaattctt ggatcttagg
    33361 ttggttgctt cctcctgcca tggccatgtc tggtttacca ccaccacgtc catcgatgat
    33421 tggtgctaat tctttgacaa ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag
    33481 gacattgact ttgtcaccga tagcggcaac taggacaaga agatcagagt agtctttttg
    33541 tttccagtta tctgcaaagg tacgaagggc acctgcatcg gatacagaca cttgactagc
    33601 aatgtaacga tgaccgttga cttccttaac atctttgaag atatcgcctg cggctgcagc
    33661 tgcggctttt tctttcaact cagcattttc tttttgaagt tgacgaagtt gttcttgaag
    33721 tccttctacc ttgtgaggta cttccttgac ttgaggtgct ttcaaggttg ctgcgacagc
    33781 tttaagagca tcctcttgtt cacgataggc ttcaaaggct tccttaccag tcactgccaa
    33841 gatacggcga gttcctgaac cgattccttc ttctttgaca attttgaaga gaccaatctc
    33901 agaagtgttg ccaacatgag taccaccaca aagttcaata gagtagtcac cgatagtcac
    33961 gacacgaact tccttgccgt atttctcacc aaagagggcc atagctccca tttctttagc
    34021 agtgtcaata tccgtttcaa ctgtcttcac ttcaagtgct tcccaaattt tctcgttaac
    34081 ttgctgttca atcgcacgaa gttcctcagc agttactgct tggaagtggg taaagtcaaa
    34141 gcgaaggaat tcaacttcgt taagagatcc tgcctgtgtt gcgtggtttc caaggatatt
    34201 gtgaagggca gcgtgaagca aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg
    34261 attgctatca attgccaagg tatattcttg gttcaaggca agcggtgcaa ggacttcaac
    34321 tgtatgaagg gcttgaccat ttggggcttt ctgaacattg gtcacagtag ccacaatctt
    34381 acctgactca tccaagattt gtccgtagtc agctacctgt ccacccattt cagcataaaa
    34441 tgacgtttcc gcaaagataa gagaggcagt tccttctgaa acagctccta cttctgcatt
    34501 gtcagcaacg atagctacca atttagaaga caattggcta gtattgtagt tgaagacact
    34561 ttctacagtg atgttttgaa gagtttcatt ttgcataccc attgagccac ccttgacagc
    34621 tgacgcacgc gcgcgttctt gctgttcttt catggctgct tcaaaacctt cacggtctac
    34681 agtcatacca gcttcttcag cgatttcttc agtcaattca actgggaacc cataagtatc
    34741 atagagttta aagacatctt gaccagcaat gacagattga cctttttctt tcaagtctgc
    34801 cacaatgcct tgggcaaagt gttgacctga gtgaagggta cgggcaaatg attcttcttc
    34861 gctcttaacg attttctcaa taaagtcacg tttctcaagc acttctgggt agtagctttc
    34921 catgattttt ccaacagttg gaaccaattt gtaaaggaaa ggctcgttga tacccaattt
    34981 ttgaccatgc atagaagcac gacggagaag acgacgaaga acataaccac gaccttcatt
    35041 tcctggaagg gcaccatcac cgatagcaaa tgaaagagaa cgaatgtggt ctgcgataac
    35101 cttgaagctc atgttgtcgc catcttggtc ataaacctta ccagacaatt tctcgacttc
    35161 acggataatc ggcatgaaga ggtccgtttc aaagttggtc ttagcccctt ggataacggc
    35221 caccaaacgc tccaaaccag cgcccgtatc aatgttctta tgtggcaatt ccttgtattc
    35281 gctacgagga acagcagggt ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat
    35341 ataacggtcg ttttcaatat cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa
    35401 ggcttcccca cggtcaaaga agatttctgt atctggtcca gaaggtcccg caccgatttc
    35461 ccagaagttg tcctcaattg gaatcaagtg acttggatcc actcccactt caatccagcg
    35521 gttgtaagaa tctttatcgt ctggatagta ggtcatgtaa agtttttcag cagggaaatc
    35581 aaaccattca gggcttgtca aaagctcata agcccaagtg atagcttcgt cacggaagta
    35641 atccccgata gagaagttcc ccagcatttc aaacatggta tggtgacgcg cagtcttccc
    35701 tacgttttcg atgtcgttgg tacggatagc cttttgggca ttggtaatac gtggattttc
    35761 agggataatg gtcccgtcaa agtatttctt aagggttgct accccagagt tgatccacaa
    35821 aagagttggg tcatttacag gaaccaaact tactgatggt tctactgagt gacctttggt
    35881 cgcccagaaa tcaagccaca tttggcgtac ttgtgcacta gatagttgtt tcatattgtc
    35941 tccttattca cttgtttaat gtgattggct ttccagcatt tccacatagt caatcgcgac
    36001 acagagggaa atgactaggt ctgcataagc gtcttcaaga accgttacgg tataggtaga
    36061 ggtcagatgg aagagttcct tcttaatttc cgcaatcaac tgatcgcgat catccagcaa
    36121 tttgaaattc aaatcccaga tattgccctc gatacgaaga cctagattat caaactcata
    36181 cttatctcgc cagaaggtca acttcttacg aatgacaaaa ctcgagccat cccgaagctg
    36241 aatctcaaaa cgaggaagca aggtcaagat ttctttactg atctgactga cttgttcacc
    36301 agccgcatca tagatggtaa aagttttggg aatcttaaaa aatgatccct ccacctgata
    36361 ggcaatttct cccctgtcat ccttgatagc gaagcgttcg cctccaagac gaaacttttg
    36421 tttgacaaga aatgttttca tcaacacctc caaaaatcaa aagacaagct catatcacga
    36481 agggcgaaaa accgcggtac caccttcatt caatgaactt gtcattctct tgttcttatg
    36541 caattgtatg attgagtagc atgacttcct agcttagatg gctcgcagca ccgccatttc
    36601 tctggactaa gacaagtgaa aatcaattct caactttctt attataacgt ttttttaagc
    36661 ttgcgtcaac tggaaatgat ctccgttgaa ttagaccaat tccctacatc tctgattact
    36721 ttttcaggat atattttttc ttactgccat ttttcttttt atcccaaatt ttcatattac
    36781 taaacacagc tactagaata tttccaaata taaaggtgcc tatcacccaa tatatggact
    36841 cagttgttag gtattgtcga tccaagccat catttaaatg gaatagtata gcagtttggt
    36901 taacaatcat aaaggttggc cagaaacttt ttttgaaaaa agtagacatt ttcattattt
    36961 gttgccgctt tctgtaaggt taatactcaa taaaaatcaa aaagcaaact aggaagctag
    37021 cctcaagctg tacttgagta cggcaaggca acgctgacat ggtttgaaga gtataggctt
    37081 agtatactac taggcaagca aataagcaaa taagcaaata agcaaataaa caactagaat
    37141 agaaaaagat agggctctaa aaactgactt ctattcctta aaaacgaacc agcttgactg
    37201 attcgtcttc ttacgtttat ctcctacttc cgatacattt taaactgtag gaagaggtcg
    37261 ctatatttcc ctgtccattt atggtcaaat ttctcataaa cttctaggtg tttcatggtt
    37321 tcaacatcgg gatagaaggc cttatcttcc tttgtttcct ctgggagcaa ttccttcgct
    37381 ggtaggtttg gtgttgaata gccgacatac tccgcatttt ggagagcatt ttcaggtttc
    37441 aacataaagt tgataaaggc ataggctgag ttttggtttt taactgtttt gggaatgacc
    37501 atattgtcaa accaaagatt gctggcctct gtcggtacca cataacgtag attttcattt
    37561 ttttctaaca tttggctggc ttcaccagag aaggtcacgc cgattgcaac attattctga
    37621 atcatatagc ccttcatctc gtccgcaacg atagccttga tatttggagt cagtttgtag
    37681 agcttatcca ctgtctcttc caactgctgc agatccttgg agttgaggct gtagccgagg
    37741 gaattgagtc ctagtcccag cacctcacgc gccccatcaa agagcatgat agaattctta
    37801 tactccggct tccaaaggtc atcccaatgc tcaggcgctt catctaccat ggtttcgttg
    37861 tagacaattc ctaaggttcc ccagaagtaa gggatggaga atttattacc tgggtcaaag
    37921 gactggttga gaaactctga tccgatattt tcgattcctt caatttttga ataatcaagc
    37981 ggaaccaaga ggtcttcgtc cttcatcttg ttaatcatgt attcacttgg aatggcaata
    38041 tcgtaggtcg ttccaccctg ctttatctta gtgtacatgg cttcgttgga gtcaaaagtc
    38101 tcgtactgaa cttgaattcc tgtttcttct gtaaactgag tcaagagttc aggatcgata
    38161 tagtctcccc agttatagat aaccaatttt tgactatctc gactattgat tttactatct
    38221 aaatgagtcg caattcccca caagacaagg ataatcgctg caattcctgc taaaaatgaa
    38281 tagatttttt tcatgcttgc tcctccttct cacgagagat aaagtaataa cctacaacta
    38341 ggataatact aaagagaaag actagagcag acagggcatt gatttctaag gaaatcccct
    38401 tgcgagcacg agagtaaatc tcgactgata gggttgaaaa gccatttcct gttacaaaga
    38461 aggtcacggc aaagtcatct aacgaatagg tgaaggccat gaaataacca gtaatgatag
    38521 acggagtcag gtaaggaagc atgatttcct tgaacatctg aaattgacta gctcccaagt
    38581 cataggccgc atgaatcatg tcgccattca tttccttgag tcgaggcaag accatcaaga
    38641 ccacgatagg aatggagaag gccacgtgac tagatagaac ggtcaaaaag ccaagtgaaa
    38701 acttgagttg ggtaaagaga atcaagaagc tagcaccaat cataacgtca ggcgcaacca
    38761 tgaggatatt attgagtgat agaaaggctt cttggtattt cttacgagac tggtagatgt
    38821 aaatggcacc aaaagtcccg ataatggtcg ctatcaaggc tgataggaag gccaagaaaa
    38881 atgtctgagc caaaatcagc atgagtctcc catctccaaa catggtttca aagtgagtcc
    38941 agctaaaacc tgtaaagcta ttcatatcat caccagcatt aaaggcatag ccaatcaagt
    39001 aaaagatagg caggtagagg accagaaaga ccagtcccag ataaaggttg gcaaattttt
    39061 tcatcgttct ctcctttcct tagtcaccca catggtgatg aacatggtca ggatgagaat
    39121 cacaccgatg gttgaaccca taccatagtt gtcattggtt agaaaattct gctcaatagc
    39181 cgtccccaag gtgataacgc ggttcccacc aatcaaacgg gtcagcatga agagactcaa
    39241 acttgggata aagaccgact gaaccccact tcgcacaccg ttcatagata gagggaagat
    39301 gacatgacgg aaggtctccc acttagttgc accaaggtca taactagcat tgatgagatt
    39361 attatccata tcgtctaaga cattgaaaat cggcaaaatc ataaagggga gctcgatgta
    39421 gcttgcgaca aagataaagg aaaaatcggt aaaaagcaac tgttgtgaac caattccgat
    39481 aaattccaag aattggttaa tagagccatt ttgaccaaaa atcccgataa aagcataggc
    39541 tttaaggagc aaattgatcc aggtaggaag gataatcagc atgagccaga gttgacggtg
    39601 cttgagacgg gtcaaaaaga gggctgttgg atagctgata agcaaggtca caaaggtcac
    39661 aatccctgca taaagcactg agttgaaact cattttgagg taggtcaagt tttgtgacgc
    39721 aaagtaagat ttataatttt ctaaactaaa ctggccttca atgttgaaaa aggattgtcc
    39781 gaaaatcaag accaagggtg ccaatacaaa gagggcaatc caaagcatgt agggcactac
    39841 aaagagttta gagcttgttt tcttcatctc tttcctcctc gatcgcattg atcagacctg
    39901 cttcttgctc ttcgatttcc acgtattctt cgatacgagc atcgaactct tcttcggttt
    39961 cattgagacg catgatgtgg atgtcttctg attcaaagtc cagaccgatt tcctcaccca
    40021 cgatggcctt acgggttgag tggatcatcc attcatttcc aagttcgtca taggcgataa
    40081 tttcataatg aactccacgg aagagctggg tgtcgacctt aacttggagt ttgccttctt
    40141 caggaagggt aatgcgcaag tcctctggac gaataacgac ctcaacaggt tcatttggct
    40201 tcatcccacc atcaaccgct tcaaagcgtt tgccgttaaa ttcgaccaag tagtcctcaa
    40261 tcatggtacc tggcaagatg tttgactccc cgataaaggt ggcaacaaag tggttgattg
    40321 gctcatcgta gatgtccaca ggggttccag actggacaat ctcgccatca ttcataacga
    40381 aaatccagtc actcatggca agagcttctt cctgatcgtg agtgacaaag acaaaggtaa
    40441 tgcccaatcg ttgttgtaat tcacgcaatt cgtactgcat gtctgttctc aatttcaagt
    40501 ccagcgctga taaaggctcg tccaacaaga ccacacgggg ttggttgatg atagcacggg
    40561 cgatggccac acgctgacgt tgtcctccag aaagtttgcg gatggaacgt ttttcataac
    40621 cttccaactg aaccatcttg agaacttccg ctacgcgttg ctcgatttct ttcttgtcaa
    40681 tcttgcgcaa gcgaagtgga aaggcaacat tttcaaacac attcatatgt gggaacaagg
    40741 cataggattg gaagacagta tgtacgtcgc gcttgttggt tggaatatca ttgatacgaa
    40801 caccgtctag catgatatct cctgtcgtcg catccagtaa acctgcaata atgtttagga
    40861 tagttgattt ccccgaacca gatgcaccta gaagggtgta gaatttccct tcttccaact
    40921 caaagttgat gtctttgaga accttggtgt tgctgtcttc aaaaacttta gagacgtttt
    40981 tgaattcgat aattggtttt ttcaattggc ataaattcct tctttttcat agattaaccg
    41041 atcggggctc tgtcaggtcc ccactacctc ttgcagggag taaaaccacc tgcatacatc
    41101 ttcgctaccg ataggctttc accccccttt ccatgacata gcagcagctt ttcaaataca
    41161 gcttcctact tgctttcacc caagatccgg acttctcttt caagcgtaat acctgagtgt
    41221 tccttgactt tttcgataac cgattggatc aagtcctcgt agtctttggc cgttccatct
    41281 gcgacattga tcataaatcc tgcatgcttt tctgacactt ctacgccacc gatacgatag
    41341 cctttcaagc cagcttctga aattaactga cctgcaaaat gcccgactgg acgcttaaag
    41401 accgagccac aagatgggta ttccaaaggt tgcttgagtt cacgtaggtg cgtcaagcgg
    41461 tccatttcct gcttgataac ctgatgggtt cctggggcta gggcaaattt aactgacaag
    41521 acaactgcac cagactcctg aatagctgaa tggcggtaac caaaagccaa gtctttagca
    41581 gacagggttt cgatttctcc atccttggtc aagaccttac aagactgcaa tatgtgagca
    41641 atctcgccac cataggcacc cgcattcata aagacagcac cgccaacgct tcctggaata
    41701 ccacaagcaa actcaaagcc agtcaaacta tgacggaggg caatgcgagt tgtttcaatc
    41761 aagttagccc cagcttctgc ttcaatggta tagccatcaa cagaaacgtt attgagcttg
    41821 tcacacaaga tgacaaatcc acgaatccca ccatcacgaa cgatgatatt gcttgcattg
    41881 ccaagaacca tccaagggat attttcttgg ttggcaaatt tcacaaggcg agccaactca
    41941 aaacgatttc gtggaaagac caaataatca gcctctccac ctacttttgt ataactatag
    42001 ctatgcaagg gttcctgaaa acggatatca attccttcta agatttcaag cattttttct
    42061 cttacagaca tgtcactctt ccttttacaa aattcattcc attataccat ttttagagac
    42121 atttgacgac cataaaaata ccttgtttgg attttgcata agaaaaagag gttcccctct
    42181 ttttatgatt ttttacaaaa gatttccttg gttccatagg cgaccagaac gagctccagt
    42241 gctagaatca cttcaaccaa gactggattt gtcaaccagc ctacttggaa aagagatggt
    42301 gccagatcaa agaaggcatg caagccatag gctgttagga gataaatcca tttcttctgg
    42361 cgaacagctt gataaaccca aactgtcaaa agtaattgga aaccaagcgc caagattcgc
    42421 tcaaaaccaa gcaaataaat ctgccagacc gaaagtgact gaatggtttt taacatattt
    42481 tcagacagta attgcataac ctgtggattc tgagtttgaa ctgccgaaag aacaatgtaa
    42541 agattgagta aactagtaag gcctagaaaa atcaactcca agccaccatg ccccaatcca
    42601 taggccaagg cgtctgcctt ttccaaactt ctctttttct ccaaccattt gaagaaaaca
    42661 agacgagccg tttcctcaaa aaatgctacc atggctaggc catagataat atagataagc
    42721 ggatgaactt acaagagggc aatactaccg tctttttgag gatgcaaaat caagatatgc
    42781 accagttttt ccaaaatctg cgaagagaca aagaaagcga ctgcacccaa gtccaagaca
    42841 gctagattaa tctggtattt ctttttggca aaccaaatgc ttcctatcag aaaagctagc
    42901 aacagcaaca tggtaataat gatatgaatg gtcattttct tctcctattc tgccttttca
    42961 atatcttttt tcatctcgtc aacattgaac ttagcaaaca agtattgacg gtcttggact
    43021 gggaaacgtt ggtccaactg gtcaactgct cccacctcga taatgccttc cttgatgaca
    43081 aaatccatga catgtccacc gaaggtcaaa tcatctgata tgaagtgcag atggtagcct
    43141 gccacactga ccccatggaa aatctcaggc gtccagaaac caacaatagt ccccgcaaca
    43201 ttgtcacgac tatattccgg ttgatgggtt gcgacatcag caaacttggt atcgggtgtt
    43261 gacttaggaa tcatacgcac atgcatatgt gaaaattccc cccgaatctt gatagagcgg
    43321 aaaagatttt ccccatcata ataagactca attcgttctt tcaattcctt gtctgtcatc
    43381 tcaaagcgct ggcggaaaat gacctctgcc tgatgcggta ccactgcagc gtaaggaata
    43441 agggcatctg gtgacacttc cacaatttct ggctggtctc ctgacccttt ggcctgataa
    43501 gccttgccat ccaagacaat caattcccca tcaatggaat ccaaggttcc caaaccaagg
    43561 tcaccatgtt ctagcaattc tcctactgtc atagtaccac cataaaggcc agccatcaag
    43621 gctccaagag tattgtattg aaataatttc actggttcct gcacgttctt atccattcac
    43681 tttcttgtct gttattctat aaatcttact cctaagtata ccacatttgc ccctagatgt
    43741 gaacgagaga aacgctctag acattgccaa gaaggaaaaa cagggtacaa tgtaacaaaa
    43801 tcaagggagg tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa
    43861 aaatggtatc gagtctggac gatttccgac gggtagcctg agattttgac agaaacaaaa
    43921 cttgcactag cacaacaacc cctaaggaac acacttccct aggggtcgct ttttatttaa
    43981 ctaaatcatt atttattttt tgttcctagt aaacataaat attgtattaa taattgcaaa
    44041 aataaatgca aacaaaagga ttttccaaag gataaatttt tgtaacacta aatatgcata
    44101 tacaaatcca atcaaaaagc taataatccc atcttttatt aaaaagtttt tatcacgcat
    44161 tattccagac cacactgaac tgcccaaata gccaactgac cagcaatgat ataaatattt
    44221 gttttaagtc cattagcttt aacaaatctt agtaccactt tagctaattc tgaccaagcc
    44281 tttttctgcg catacttaac aattagcgaa acattgatca tagcaaaaaa ttcatctcgt
    44341 atttttcctg ctatacatcc tcccatctca tcccaaggga ctctgtcata gggattatta
    44401 atattagttt ctaattcatt ttccgcaaga gcaatatctt tttgagaaaa gtttttataa
    44461 acatattcag taaaattttt ttcattaact ccatttctaa acatttgttc aagaacattg
    44521 gctacatcat cgatttgttt ttgttcttgg gtactaattt cagaaacttc cgtagtagtt
    44581 acatcatcag caaatactct aacagaagct atagaaggag acataataga aaatagtgat
    44641 aatacaacaa gagctgaagt tacaattttt ttaaatttca taaaaaacac tcctttcaag
    44701 tcacaaatat atattactga taaaataact tgattttctg atttaaaact cctttctaac
    44761 aagttattcg tatgctttta ttttttagtt ctattatacc acaacaagaa aacgatttca
    44821 agcattttcc taaaaatatg tacaagtaat atgtacaagt aataagggga aattagcata
    44881 aaaacttttt aaaacaaatc aaccccagat aaaaatacac atgttgtttt aaagacaaaa
    44941 aagggtacga aaaactgtca catctgcatt tgattgctct ttgatttcaa aaaagtatta
    45001 aaaatgggag tataccacat ttgcccctag atgtgaacga gagaaacgct ctagacattg
    45061 ccaagaagga aaaaaaaggg tacaatgtaa caaaatcaag ggaggtctgg aatgaagaaa
    45121 caaagcaagt acaaagaggt cgtttcctat ctgaaaaatg gtatcgagtc tggacgattt
    45181 ccgacgggta gtcgcctgcc ttctatccgt caactgagcc ttgactttca ctgcagcaag
    45241 gacaccattc aacgagccct gctggaatta cggcacgaac aatatctcta tgccaagcct
    45301 cagagtggct actatgtatt agaacaaggg caacatcaag acctagaaat cgaggttacc
    45361 gacgaacatg ccagtgccta tgacgatttc cgactctgtg tcaatgaaac cttgattggc
    45421 cgagaaaact acctcttcaa ctactatgac aatcaagaag gattagaaga cctaagacag
    45481 tccattcaca aactcctctt tgagcaagct ctctactgca aggctaacca actagtactg
    45541 acttctggaa cccaacaagc cttgtttatc ctctctcaaa tatcctttcc tagacaagcc
    45601 aaggaaatct tggtggaaca gccaacctac catcggatga atcgcctctt gattgcacag
    45661 gggctggact atcaaacgat tgaacgaggc attgatggga ttgacttgga ggagctggaa
    45721 ggccacttca aaacaggaaa aattaaattt ttctacacca ttcctagatt tcactatcct
    45781 ctgggacatt cctattctga gcaggacaaa cgatctattc ttaacttagc tgccaagtat
    45841 gatgtctata tcgtagagga cgattatctg ggtgatttgg actccaagaa gggccaaacc
    45901 ttccactatc ttgatacaga ggagcgtgtc atttatatca agtccttctc gaccagcctt
    45961 tttcctgccc ttcgtattac agcactcatt cttccaaatg ctatcaaaga agcatttgtg
    46021 gcctacaaaa atatcctaga ctacgacagc aacctcatta tgcaaaaggc cctgtcactc
    46081 tatattgaca gtcaattgtt tgaaaaaaat cgtttggctc gcttgaccaa tcatgaatct
    46141 taccaaaaac aaatcgagga aaggataact aaaacacctt gtccccttcc tcattatccc
    46201 ctacacgatg gtttattgct agacctgaga cagtatccta aaatcgccag tctcaaacac
    46261 agtcaactgg gcttggactt ctttgaagag gcctatttaa gcacctgtcc ttatcaattt
    46321 gccaaggtgt ccctagacaa tctggaaaat gttttaaact atttaaaagc agaattggaa
    46381 tgacatccaa ctctgctttt tcttattctt caacttcagt taaacttgct gctttttcaa
    46441 gatagctttg gtaagttcct tcatccttaa gtttttggat gaccttgtct accacttctt
    46501 tcaaatcatc actatttttt ctaagagcaa cggcattggc gtcgccgtcc ttcatcttca
    46561 agctgacagt tgcgacagct aagccagcgt ttttagcagc ataactaagt gcaacaggct
    46621 catccatatg aacagcatct acttttccag cctgcaattc attgactgct tcacccatat
    46681 tagttaggga agttaattga gcttttggca attgttcctt gaccattgat tctggaacag
    46741 tccctttttg ggctgcaata ttagcacttt ctaggctagt taaatccttg tatttttcca
    46801 catcagcctt acgaaccaag aaactaatct tgttttcata gtatgggatt gaaaaatcaa
    46861 agacttcttt tctctcgtca gtagcactaa ttcctgcaac tgctaggtca gccttaccag
    46921 tttgaagact ggtcaaaaca ttatcaaaac tcatgcttga gatttccaac ttaaccccaa
    46981 gttcatcagc gatagcctga gccatgtcga tgtctgcacc gactacctgg ttctttccat
    47041 caaccaatga ttgaaattca aagggtgcat agtcaggact ggttgccaca actaatttcc
    47101 ccttttgctt aatggcctca acagctgact gagaaccatt agaacctgac tggcaagcta
    47161 ctaagaagaa acttgcaaga aaattacata aaacaaatat ccattttttt gatttcataa
    47221 ataaacaacc tctctgttaa ttttgtataa ttataacgat atccaagtta cttgtcaagt
    47281 gttttttaaa tttttatctc aaaaatattt tttcgttcaa aaaaaggagc catcagttga
    47341 tttcaagctc ctttttatac agaattaaac tattttatag ttcgacaatc ttacctgttt
    47401 caaagtagac aacccattca cagatatttt tagcatagtc accgatacgc tccaagtagg
    47461 aaataacttg gaaataatca cgacccgtaa caatggcttc tggatttttc ttaatctctt
    47521 cagtcgcaag gtcacggata gtttcaaaat agtggttaat ttgctcatcc atggaggcca
    47581 cccggtatgc gtcgtcaaca gaaccattaa gataaagatc aagtgctgct tcaacaacgc
    47641 ttttaacttc acgtcccatt tttttaattt cttcctctac agctggaatg cgctcttccc
    47701 ccttcatacg gatggttgcc tgagcaatgg ctacagcgtg atcccccata cgctccacat
    47761 ctgatacagc cttaaggaca gtcaagactg tacgcaaatc ttgagagact ggttgttgga
    47821 gtgcgatcat ttcaaatgat ttcttttcca gtttcacttc gtattcattt acttctgcat
    47881 catcttcgat gacctctttt gccaggtcac ggtcatgcgt gacaaaagca cgtaccgtac
    47941 gattgatttg tgagagcact tcttgtccca tagcgtagaa ctggttatgt aatttctcta
    48001 aatcttcttc aaattgagat cgtaacatct ttcatctcct tatccaaatt ttcctgtaat
    48061 atagtcttcc gtttccttgt gttggggatt aaggaacatc tgcttggtat cattaaattc
    48121 aatcaaatct ccatctagga aaaatcctgt cttatcagag atacgtgaag cttgctgcat
    48181 ggaacgggtt accagaagca tggtgtactt gtcttttaga ccatacaagg tttcctcaat
    48241 tttaccagct gaaatcggat ccaaagccga agttggctca tccaagagga tgattttagg
    48301 actagttgcc aagacacggg ccacgcagac acgctgctgt tgaccacctg acaatccaat
    48361 agctgaatca tatagacgat ccttgacctc atcccagata gaggcacctt gcaaggcttt
    48421 ttctacggct tcatccagaa cctgcttatc cttaattcca ttgatacgaa gcccgtagac
    48481 aacattctca tagatagtca tagggaaagg attaggttgt tggaaaacca ttccgatttc
    48541 cttacgtaat tcaaccgtat ctgtacgcgg actgtagatg ttgtgaccat tgtacaccac
    48601 ggatccagtt gtggtcacct ctggattgag atctcccatg cggttgagag acttgaggag
    48661 ggttgacttc cctgatccag atggaccaat caaggctgta atttccttag gttggaaaga
    48721 tagggaaaca ctattcaaag ccttcttttt attataataa acggacaggt ctgatacctg
    48781 taaaatcgca tctgtcatac ggtttccttt ctaaccaaag tgaccagata catagtcatt
    48841 ggtggactgt agcttggcat tttggaaaat agttgcagtc ttgtcatact caatcaaatc
    48901 acccaagtaa aagaagcctg tatagtcact tgcacgagca gcctgctgca tattatgcgt
    48961 tacaatgatg atggtaaagt ttttcttgag ctcaaacatg gtctcttcta gttgcatggt
    49021 cgcaatcgga tccaaggctg aggctggctc atccattaag aggatatctg gcttaacaga
    49081 gatggcacga gcgatacaga gacgttgttg ctgaccacct gataaggtca aggctgactt
    49141 gtggagatcg tctttaacct gatcccaaag ggcagcctga cgaagggagg tttctacgat
    49201 ttcatctagg acttgcttat ccttaactcc agcacgttca tgcgcaaagg taatattacg
    49261 gtaaattgac ttagcaaatg gattggggcg ttgaaaaacc attccaatgt gtttacgcat
    49321 ttcataaacg ttgatttctg gacggttgac atcaattcca cgatagagaa tctgcccagt
    49381 tactttagca atatcaatgg tatcattcat gcgattgaga ctgcgtaagt aggtagattt
    49441 ccccgatccc gacggaccaa tcaaagctgt aattttattt ctttcaaatt gcatatcaat
    49501 ccccttaatg gattcatttt taccatagta aacatggaca tccttagtag aaagggctac
    49561 tttttcttca ggaaaggtaa ggatatgctt ctcatcccag ttatatgttg acatggcttc
    49621 tcctttaggc agcggttaat ttcttgtgta gatagcttcc gaacttacga gctccaaagt
    49681 taaaaatcag gataaagatc aggagcacag cggcagaacc tgctgataca atggttccat
    49741 ctggaatagt gccttcacta ttgactttcc agatatggac agccaaggtt tctgcttgac
    49801 ggaagataga gatggggcta gtcacactga ggatattcca gttagaccag tcaagagctg
    49861 gcgccgattg ccctgctgta tagatcagag ctgcagcttc gccaaagata cgaccagatg
    49921 ccaaaacgac acccgttaca atacctggaa gcgcttctgg aataacaaca tgaaccactg
    49981 tctcccagcg agaaatccca agagccagac cagcctcacg ttgggtatgg tgaacgtgtt
    50041 tcaaactatc ctctacatta cgcgtcatct gaggcaagtt aaagactgtc aaggccaagg
    50101 cacctgaaat gattgaaaat ccatactcaa actggactac aaagatcaag taaccaaaga
    50161 gacccaccac cactgatggt aaagaggaca agatttcaat acaagtccgc acaaagttgg
    50221 taacaggacc ttttttagca tattcagcca agtaaatccc agctcccata gaaagaggta
    50281 cagaaataat caaggtaatg accaatagga aaaaggaatt gtaaagctga atgccaatcc
    50341 caccacctgc ttgaaaagca gaagaccttc cagtcaagaa agaccaagag atatggggca
    50401 agccccgaac caagatatag agaatcaagg aagccaagat tgtcacaatg atgctagcaa
    50461 tcgtatagag gacagctgtt gcaagtttat ctaatttctt agcgcgcata atttttcttt
    50521 cctctttctt tcgtaatcaa tttaatcaca ctgttaaaaa ctaaactcat caagagcagt
    50581 accaaggcca gtgaccagag aacattatta tttacagttc ccatgacagt gttcccaatt
    50641 cccatagtta atatagaagt taaagttgca gctggtgtgg tcaaggaagt tgggataaca
    50701 gctgagtttc cgacaaccat ctggatagct agagcctcac caaaggcacg cgccatccca
    50761 aagaccactg cagtgaaaat accagaacgg gccgccttca agatcacacg ccagatagtc
    50821 tgccagcgag tggctcccat agcgaaactg gcttcacgat aataacgagg aaccgcacgc
    50881 aagctatccg ttgtcataaa ggttacggtc ggcaaaatca tgacaaagag gacggaaatc
    50941 cctgacaaaa tcccaaaacc agtcccacca aagacactgc gaacaaaggg aacgacgact
    51001 tgcaagccaa taaatccgta cactactgaa ggaatcccaa ccaggagttc aatagctggt
    51061 tgcaaaatct tcgccccttt tggtgatact tcggtcataa aaactgctgc accaatagca
    51121 aagggtgttg cgataagggc tgagagaatg gtaacgataa aggaacccaa aatcatagga
    51181 agggcaccaa attctttact agaaggattc caagttcctc ccaaaagaaa gtcaaagata
    51241 ttcacaccat tgacaaagaa ggtcgacaag cctttttgcg ctacgaaaac caaaatcatg
    51301 gccacaagga tgactatcaa agaaagacag gcaaaggtca aaccttttcc taatttctcc
    51361 agacgagaat tctttgatgg aagcaacatt ttcttagcta attcttcttg attcattatt
    51421 gtctcccttc caacactgtc acagttccgg cagcatcttt ttcaaccttc atttccttaa
    51481 tcggaatata cttcaatcct ttgacaatcc cttcttgggt ctcatccgag agaacaaaat
    51541 tgagaaattc tgcagccaac tcattgggct gccccaatgt atacatatgc tcataagacc
    51601 acaagggcca attattgcta cttatatttt ctggacttaa gtcatagcca ttcaacttca
    51661 tgcttttgac cgaatcatct atataggtaa gagataaata agagatagct cctggacttt
    51721 ttgatacgat tgattttacc gctccatttg aatcctgctc ctgactttgc atggcagact
    51781 gaccttccat aatgacagta tcaaaggtag cacgagagcc agagccggct gcccgattga
    51841 taacagagat gggtaagtcc ttaccaccaa cctctttcca attggttacc tcacctatga
    51901 agatttgacg aagttgctct gtcgttaggt tatcaacatc aacctcctta ttgacaatca
    51961 gagccaagcc agctaccgcg accttgtggt caacaagagc agaagcatca attccgtctt
    52021 tttcctcagc aaatacatct gagtttccta tatcaactgc cccagactga acctgggaca
    52081 agcctgtacc agaacctccc ccttggacat tgaccgtttt tccaacatgg atcgtgccaa
    52141 attcatctgc cgctacttca accaagggtt gcaaggcagt tgagccaaca gccgttatgg
    52201 attctccacg atcaatccag ctagcacagc ctactaaaca agccgtcagc caaaaagcga
    52261 taagagacag agcaagcttt tttctttttt tcactgtttt tctcctcgaa aataattatg
    52321 aatactgtga attttttaag tagttcttta tgagttgacg catgaattct taccaaattt
    52381 ctgcgcaatt gattatttat ataatatagg ctatattact ctttcctaac ctcctttttt
    52441 catatgtgga taaaatctct tgtctatccc ttcccccatt gtcacccatt atagtcattt
    52501 cgtgtctctt tttccccttt ttaatgcaag ggaaattact cttcttagat gataatccaa
    52561 aagctagaaa ggtatctcaa acctctctac tctcccagac tagtttacaa ctaaaaggaa
    52621 aagattctat tttatgagaa atctagttta caagcggtaa gaacgctaat aactaaactt
    52681 cttgtactct ttgaaaatct cttcaaagca gtgttttgag ctatctatgg ctagcttcct
    52741 agtttgctct ttgattttca tcgagtagta aaactacatg tgatggcaat caagatatca
    52801 agaatcatcc tactaaaaaa atccatactt tcactataac atagaataag atatttgact
    52861 agcattttca tttgaatctg aggccttttg gaaaataatt tttcaaaaca tttccagtaa
    52921 cctttgcaaa gcccaagcca ttgcctttaa ccaaaacttg gtaccaacca tttggcagac
    52981 tttctgccag ctgaacggtt tctccagccg catacttgac aaacgcttct tggccaattt
    53041 caaccgactg ttcgacctga ctcggtttca aggctaaacc aagagcgaaa ctgggctcaa
    53101 agcgtttctt cttaaaagta cccagatgca gtccattgcg agcaatcttg agcttcccta
    53161 aatctggcaa aagttctggc aagagataaa gctggtctcc aaaaatctgc aagatacccg
    53221 gtagattgac cttcaaatgg ttttgggcaa attcctgcca caaggcaact tgttcacggc
    53281 tgaggttact cttacttgcc ttaaatttag gagctggatt gttaccctta aactgtagat
    53341 gggcaacaaa ctgaccctct cccttaaact gatgagggta catccgagcc gtttctggca
    53401 ggtcaatacc agctaccatt ccattgatat gctctactgg caacaagtca aaatcatact
    53461 cttccagcaa ccaattgaca atctcttcgt tttcctcggg tgcccaggta caggtcgaat
    53521 aaaccagacg accaccttca gctaacatgg tcactgcatc ctccagaatt tctctttgca
    53581 agctagcaca ttgactcgga taatctaagc tccaatagtc catagcatca ggttgcttac
    53641 gaaacattcc ttcaccagag caaggggcat caagaacgat taagtcaaaa tagcctttaa
    53701 agaccttgac caagcggtcg gcagattcat tggtcaccac gacatttgtc gctccaaaac
    53761 gctccatgtt ttcaaccaaa atcttagccc gtttgcttga aatttcattg gaaacaagta
    53821 gcccctcccc tgctagatag gctgccagtt gagttgattt gccccccggt gcagcagcca
    53881 agtccaagac cttcatacca ggactgggtt gggctacttg agccaccatt tgagcagcag
    53941 gttcttgcga ataaactaaa cctgtagcat gctcaggcga tttccctgaa accttcccat
    54001 agtggcccca aggggtttga gtaatggcat cagaaaagga aagttgctct tcttttaagg
    54061 gattgacccg aaaggccgaa accgcttcct cctcaaaaga ggcaagaaaa tctcttgcct
    54121 catctcctag tatttcttta tatttttcaa caaatccttc tggaaatttc atttaagttc
    54181 ttttcctttc gtaaatatag gactgaattt cctcctgcat ctcaagaggc accatcatga
    54241 ccggctgtct ggtttgaaaa tcaggagctt caccaaaaag ggtcacaacc cgatagccca
    54301 gactttcccc taaaatacta gctgcggcat aatcccatgg ttgcagatag gtgagatagg
    54361 tcaacaaatg ccctgacaaa atcttggcaa aactaatggc cgcacttcca tagacacgaa
    54421 caccaagaac cgctcggctc aaatcagcca gcccccattc attggtttcc agcataccac
    54481 tattccctgc aatgagaaaa tctccaagtg gtttagtttt aaaaggagct aggggcctat
    54541 catttagaca aactggaaat tccccaccac cgtggtaaca atcccctttg accacatcat
    54601 aaatcagacc aaactgtccc tgaccatttt caaaataagc catcataaca gcaaaatctt
    54661 cctgctgggc tacaaaatta ttggtaccat caatgggatc aatgacccaa accttgccct
    54721 cttgaaccga ggctcgcaga caaccttctt cagcacaaat cttatcctca ggataacggg
    54781 acaaaatctc accaaccaag agttcctgaa cttctttgtc cagtctggtc accaaatctg
    54841 ttggagagga cttggtttca acacgcaagt cttcctgcat atggtcaaga atgtactggc
    54901 ctgctttctt aacaagctct ttagcaaatt caaatttact ttccaagaga aatctttcct
    54961 tccccttttt ctttggcagc ctgaactgct cggtaaagtg aatagccact aaccgtttca
    55021 aattctcgtc ccaaacgttt ctcttcgctc ttgcttggca cgaccgcttt gaatccctta
    55081 taggagtcca gtaacttttt agcctctact ttgccttcat aggcagcttc aacatcatta
    55141 aaaaaagaaa gcactgaagc aagttcttca gtgctccacg acaaatctag tgggtaacta
    55201 tactgtttgt tcattaacta ataccagctc tcattcttgc ttcttttagt tcttgcttac
    55261 gataactacg agggagaaaa gcacgaatct catcttcatt aaaaccgatt tgcatacgct
    55321 tggcatcaat aataattgga cgacgcaaaa gactaggata ctgctcaatc aaatgaagca
    55381 attccgatac cgaaatactc tctacatcaa tattcaattt ttgaaaaatt tttgaacgag
    55441 ttgaaatgat gtcatcagta ccattttcgg tcaaggaaag gatgtgttgc aattcttttc
    55501 ttgttaaagg actggtcata atattgtgtt ccacaaaggg aaccttatgt ttttctaacc
    55561 aggccttagc cttacgacat gatgtacagc tcggtgatag aaatagtgta atcatgcttt
    55621 tctcttctta tctatacttt gctacttcta ttatacaaaa aaataaagcg cttgactagg
    55681 gatttttaga aaaaaagcct attttttcaa gaaaaatagg ctttttgcga acgattgaca
    55741 caattggatt tggttaattc actcttaacg atggttttaa acgatatata tttttatata
    55801 tgtaaattaa aaacatcttt cctttcactt cctacgactt ttcagataca gatagccaaa
    55861 gaagttttca tagagggcaa aaaagaggag gaaggcatga agaaagaagg tctctggcaa
    55921 aatcataata acaggatcct tggctggatc aaaaagccag gtatcatctc ccacaaagag
    55981 aatttgatgg aaaagagtaa agaattggtc aaaaccaatc aaaactcccc caagtccaat
    56041 catcacaggt aagactacta gagccaggag actttttcga taaagagaca aaaagtcctt
    56101 tttcacaatc ctattgacaa agacatagaa acttggcagt gtcactagag ctactagctg
    56161 aaccaaatga aagagattct tgaccactgc gaaatggtgc agaccagctg ctgacgaacg
    56221 aaaatcaggc atctgtaaga cctgactaaa aggattggtc agataattca tcaagatatg
    56281 aaaattgtat tgaatggttt ctggttttag atagactcga ttcgttaagt ttagccactg
    56341 aatctccata ggatagaaaa tccaagccag ataaatggtc agaaggattg agagggagag
    56401 gagaaagagc atagagcccc aaaaggtcaa tttagttttc atcaaaatcc cactccgcaa
    56461 ggctagaaac cacatgtgtc ggtgcgattg gcaggccagc tacttcttct gccttagtaa
    56521 aacctgtcgt caccaagagc gttggaatgc cattgtcaat cccagcccgg atatcagtca
    56581 aataattgtc cccaaccatg attaactctt cacgttccaa acctaagtgc tcaaccgcct
    56641 tgtccataat gatggcattt ggttttccga tataaaccgg cttcactcgt gtcgctactt
    56701 caagcagcgt aatcagtgag ccagcacctg gcaaaagacc acgttccgtc gggatgttga
    56761 ggtcaggatt ggttccgata aaatgggcac ccttttgaat agcaagagtt gctgtggcaa
    56821 atttttcata gtcgacttgc caatccagac caactaccac gtaggcaggg ttttccttgt
    56881 cttccacata accagccgcc ttgatggctt ccttgagtcc tgcttctccg acgacataga
    56941 cagtcttttc aagccccaaa tcattcatat agtcgatggt tgccaaagtc gctgtgtaga
    57001 cagtcgatag aggcgtatcg atattaaaat tctgagccaa catctcctta acactctctg
    57061 gagtgcgggt tgtattgttg gttacaaaga gatagggaat gtcccgcttt tgcaattcat
    57121 gaacaaaagt ctctccagca gggattcggt ctttcccctt ataaatggtt ccgtctaaat
    57181 caattaaata gcctttatat ttcatctatt tctccctaaa ccttttttat ttcttgccaa
    57241 gtaatgattg cttgggcatt gataacccca tcacttgtaa tttcatgctt gctttccagt
    57301 ccagtccgtt caacagccga tgtaatcacc ccacctggtc gaacttcctt gacatacttg
    57361 aggttgattt tcttgggaat atagtgggtc aaaaaatccg ctcccatgac ctcaaaaatc
    57421 cagtccaagt atttactgtt attgacatga ccattcatat ccaagtcgta aaaacgaaca
    57481 tggtaatcct tgctgatcgg ctcttccaag gattcatact tcggtccacg gataagtttt
    57541 ttatcaaaat cagactggta aggagccaca atctcaggtt caacagcatg gacttttcga
    57601 ctgtcgcggt ccatgagaac aaaggtcgcc atcatatgga tgagctcctg ccccgcttca
    57661 ttataaatag taaagcgacg gtagcaaaaa agtcgattgt agctcaaggc ttccgtttcg
    57721 atggtaattt cttccgcaaa acgaggcaaa cgaaccacct caatatcata ttctgcgata
    57781 atccagacca gattatagtc ttccaaaatg gccttatcac taactcccag ttcaatcgat
    57841 tgcatccctg aaacttgcag tgacagcaaa atcacatctg gaagtttgat atgaccgttc
    57901 atatcagcca tatcaaaagg aattttcatt ttcatttgat aagttaagca catgatccta
    57961 ctccaaaata aatcgttctg ctacagtatc tcccaaaaag agacctctct ttgtcatgcg
    58021 aacgtggtca ccctcaatct gcatgaggcc ttgttgaacc aaatctctga caatttctcc
    58081 ataaagtcca gcaaaagact gtccaaattt ttcctcaaat cgcgccatgg aaaccccgga
    58141 tttcttgcgg agtcccaaga acatttcttc ttccatttgc tccttttgac tcaggtgatc
    58201 ttctgtaata caagcattgc cttcctcaac cgcactgaga taatgacgaa tgggaccatg
    58261 atttttatag cgtactccat tgacataacc agatgcccct gcaccaatac catagtattc
    58321 agcattgtcc cagtacatga gattgtgacg actttcaaag ccgggtttgg agaaattaga
    58381 aatctcataa tgctcaaaac ccgctcgctc cagctctgca atgatgtact caaacatctc
    58441 cgcttctagt tcctccttag gcagaggcaa tttcccacgt cgcatccggt tcataaagac
    58501 cgtatggttt tctaaaatca aactatacaa actcatgtgg ggaatatcca gtccaatggc
    58561 tttagccaca ttttccttta cttgctccat ggtctgacca ggcagagcat aaatcaaatc
    58621 aatggagatg ttgtcaaaac cagccagttt caggcgatcg atattttcat aaatatcctt
    58681 ctccaaatga ctgcgcccaa tctttttcaa catcttatca tcaaaggtct ggacacctag
    58741 cgaaacacga ttgacagccg aatttttcaa aacagctatc ttatccgcat ccaaatcgcc
    58801 tggattggct tcaatggtca actcttccaa gacagacaag tccaagtttt tagtcaagcc
    58861 attcagtaac acctccagtt gcggagccga cagggctgtc ggtgttccac caccgatata
    58921 aagggttgac aacttttcaa tatcataaga acgaaactct tccagcagat gctctaaata
    58981 gctgtcgact ggctgatttt tgatgaagac ctttgaaaaa tcacaataat aacaaatctg
    59041 ggtacaaaat gggatgtgca cataggctga cgttggtttt ttctgcatag taattattat
    59101 accacaaaga ctagattcca gataaaaatc accatcccca gatacatagt ccgtccggag
    59161 atggtgatgg tttattcttc tgttatatca atcacaatct cttctgagtc atcaagagct
    59221 tcggcttttt cttgccattg ctccttgaga ttatttaatt gattttttga tgcttctgtc
    59281 gcttgaaaag cataggattt agcttgagca agtatactgt ccacagtgat ttcacctgac
    59341 tcaacctgtt cttttgtttt cagaacaaaa tctgtagcct gctccttaac ttctgtcagt
    59401 ttttcacaga cttgctcctt ggcatactcc ggatcttctc tcaaatcatc tagaaaatct
    59461 tgagcctgac tgcaaacttg tttgccctta tcacttgtta aaaacaaggc aagagctgca
    59521 cctgaaacgg ttcctaaaag gattgaggat aatttaccca taaggattct ccttttttat
    59581 tttttgaaaa atttacttgc aagacgaaga gctgacagac ttgcaccagt cttgagtgtt
    59641 tttgaaccag ctgatgaagc tttcttgctc aagacacgcg catggtcatt gaggtctgaa
    59701 acagatagag ataaatctgc aacagcactg aagagtggat caatcgtagc caccttgaca
    59761 ttgatatcat ctgccaagac attgacctta gccaacaact cattggtgtg atgcaaggtc
    59821 acatccacat ctgaagtcaa ggttttaatc gtcttttctg tttcatcgat gacacgacca
    59881 agcttttgta cagtaatgat cagatagacc aaaaagacaa tcaaagctag ggcaacaaga
    59941 atatatgcaa cttctaacat ttagttttcc tcctctgtaa tatagtaagg ggccttcttt
    60001 cgattttgat aaataacgat cattataccg agaccgataa agacaactga cagccattgg
    60061 gacactcgaa ggctgaagaa catgagacta tctgttcgca taccttcgat gaccatacga
    60121 ccgaaaccat accaaatcaa gtaaaaggcc gtgatatgac ctcgtctgag actcttccat
    60181 ttccgtctaa aaatcagaat caaggcaaag ccaagcagat tccatagaga ctcataaagg
    60241 aaagtcggtt gacggtagct cccctcaata tacatctggt cacggataaa gccaggtaga
    60301 taatccagat tatccactgt tgcaccataa gcttcttggt taaagaaatt accccaacgc
    60361 cccaaacttt gagcaatcat aacgctaggc gccgcaatat ctagaaaatc ccaagtattg
    60421 atgagtttac ggtcagcaaa gatatagagc acaagagccc cagttatcaa accaccgtaa
    60481 atggccaaac caccattcca aatggcaaaa atctctccta aattctgact atagtaatca
    60541 aatcggaaaa taacatagta gagacgagct cctaaaatag ccaagggaaa ggctactaag
    60601 ataaaatcta aaatatcgtc tggtatgatc ttctttctag gtgcttcttt catggtcaaa
    60661 taaaccgcaa gaatcaagcc tgtcacaata cataaggcat accaacgaat ggctaggggt
    60721 cctagttgaa tagcaattgg atcaagcatt ttgcacctca tttcgagcta tgagacttgt
    60781 cagtcgttcg tcgaacaaac gggtagcatc aaagcccatt tccttggcac gataattcat
    60841 ggcagctgcc tcaatcacaa cagagatatt acgacctgtt ttaactggaa tacgaatacg
    60901 aggaatggct acgccagaaa cttcaagttc ctctgcattg tttccaagac gatcaaaggt
    60961 cttatgcgta tcgtaatttt ccaaatagac agcaagctga acctgtgaag aatccttgac
    61021 agcactcgca ccgtagagac tcataacatc gataatacca accccacgaa tttcaatcaa
    61081 gtgtttcaaa atttcagctg gttcacccca gagagtaatc tcatccttgg caaagatatc
    61141 gacacggtca tcggctacca aacggtgacc acgtttgaca agctcaagac ctgtctcgct
    61201 cttaccaatt ccactatctc cctgaatcaa gacgcccatc ccataaatat ccatcaagac
    61261 accgtgcaca ctggtacgtt ctgccaaacg agaatccaga tagctagata actctccaga
    61321 taaacgactg gtagctgcac ggctggttaa aatagcaatc ttacattctc tagcagcctt
    61381 taacatctcc tctggaacca ccaaaccacg ggcaacaatg actgctggtg tctcaggtag
    61441 aaacattttt ttcaaaactt cataacggct gttggaaggc atgctgatca gataagacca
    61501 ctccttcatc cccaaaagtt gaatccgctc tggtgtatag tagtcaaaat agcctgtcat
    61561 ttcaagacca ggtcgcgtaa tatccgctgt attgatttcc ttttcaagca attctggttc
    61621 accatagaca atatctagtc taagcttttc aatcacttct tttactaaaa ccgacatcat
    61681 ttcctccttc aaatgaattc ttctctctat tatatcaaat tgtaggagga agtttcagat
    61741 ttttgcaggc tttggagtat ttatttaaaa gaaaaaggac tagatttctc tagcctttca
    61801 tttcaattag aattttttac gtttacgagc tacttctgat ttacgtttac gttttacaga
    61861 aggtttttca tagaattcac gtttgcgtgt ttcttgaaga gtaccagctt tagtaaccgc
    61921 acgtttgaaa cggcgaagtg cgtcgtcaag agattcattc ttacgtacta ctgttttaga
    61981 catttttttc actcccttca agttcaatat ctatttcatt ctacacgtaa aaggaataat
    62041 tgtcaagcaa aaatgcggtt taattttgat tttttcttcc atttatacaa gagttgaaag
    62101 cgttcaatag aacattgctt ttttattttt cgagtaagct aagcgcttca gcatctgcga
    62161 tgatggttac atcagggtga ttttggaggc tacttgcagg taggttctca gtcactgggc
    62221 cagatactgt tccggcaatg gcttctgctt tcgactcacc ataagcaaaa agaataatag
    62281 acttggcatc caaaatgttt ttaatcccca ttgaaatagc ttgggttggg acgtcttcaa
    62341 tcttggcaaa gaagcgagca ttggcttcga tagtagactg gtcaagttct actagatgcg
    62401 tttgactgtc aaatggagta ccaggctcat taaagccgat atgcccattg cgaccgattc
    62461 ccaagatttg gaggtcaact ggatggtcag ccaaaatttg gttgtagcgt tcaacttcag
    62521 cttcagcatt gtccttaaca ccacgaggca agaaactttc tttaaatggt ttttggttga
    62581 acaagttttc ttgcatgaag taacgataag actgtggatt gtccccatca aggcccacat
    62641 actcatcaag gttgacactg gttagatttg aaaaatcaag gtcactctca acaatttcct
    62701 tgtaaaattc aagtgggcta cttcctgtcg caagtcctag agtttgagct ccattagcca
    62761 atttttcctt caaaatctca aaagcaactt ttccaccttg aacttggttt tcaactttaa
    62821 taactttcat cttttcatcc tccatttctg tctatattta ttatatggta tagaccaatt
    62881 tttgtcaagt gaaaacgatt taatttctaa aaaaagagcg tccaaacttg aaacgtgtta
    62941 taatggatag gattagaact tagaaagaat gaacaaatat atgaatacag ctgattttga
    63001 tttccacttg ccagaggaat tgattgccca aacgcccctt gaaaaacgtg atgcctccaa
    63061 actcctcatc gtcaaccgtg agacaggaga aatgcaagat aaacatttcc actctattat
    63121 tgatatgctg gaacctggtg atgcccttgt catgaacgac acccgagttc tccctgcccg
    63181 cctctatggt caaaaagtgg agacaggagg tcatgtggaa cttctcctcc ttaagaacac
    63241 tagtggagac gagtgggaag ttctggctaa acctgccaaa cgcctcaagg tcggtactcg
    63301 tatcagcttt ggtgatggcc gcctcagcgc tgtcgttaca gaagaattga cccacggggg
    63361 acgcattgtc cgctttgaat accaaggaat tttcctagaa gtcttggaaa gtctgggaga
    63421 aatgcctctg ccaccttata tccacgaaaa attagatgac cgtgaacgtt atcaaaccgt
    63481 ctacgccaag gaaagcggct ctgctgcagc accgactgct ggtcttcact tcaccaaaga
    63541 actgctggca gaaatccaag ctaagggtgt tcatctagtc tatctgactc tccatgtcgg
    63601 actcggaacc tttagacctg tttctgtgga taatctggac gaacacgaaa tgcactcaga
    63661 gttctatcaa ctttctgagg aagctgctgc cacccttcgc tctgtcaaag aaaatggtgg
    63721 tcgcgtcatc gctgtcggaa ccacttctat ccgcaccttg gaaactattg gttccaagtt
    63781 tgatgggcaa atccaagcag attctggttg gaccaatatc tttatcaaac ctgggtatga
    63841 gtggaagatc gtggatgcct tctcaaccaa cttccatctg ccaaaatcaa ctctggtcat
    63901 gttggtttct gcctttgcag gccgtgaatt agtcttagat gcctaccacc atgccatcca
    63961 agaacactac cgcttcttca gttttggtga cgccatgttt atttattgag aaagaatttc
    64021 tctaattctt ctaataccaa taaatcgcta agatattatt tcaaagaaca tctacaattg
    64081 aaactctagc tagctgtaga agacgcctag tacattgaaa ttaaaatgct tccccctagc
    64141 ttcgaaaata ttgccataga ttgcgttgac tctccaaatt gattcatcta tattttattt
    64201 cagcttccta tattttcttc gctgtttgta aatcaaaatg caagacacat gagtagcacc
    64261 atatttgtta ctcttatctg tcctctcaag agactattat gagttatttc agaatcattc
    64321 actactttga ccctgactct ccttagtctc aaaatcaaag acttatactc ttcaaaaatc
    64381 tcttcaaacc gcgtcaacgt caccttggat tatatatgtg actgacttcg tcagttctat
    64441 ctacaacctc aaagcagtac tttgagcaac ctgcgactag ttttctagtt tgctctttga
    64501 ttttcattga gtattaaaca aaaagtgaac aaatctgaat tctaatgtac agaagactag
    64561 gcttgttcac ttttttatag tcgctataag atgaccttat ctatagcttt ttatatataa
    64621 ttatatattc agacatacta ttatcaattt tgtcgcaggg aggaatctgt taacgcaccc
    64681 attcaccatt atcattgact ctatagccat ctatacttgt attgaccgct aactcacccg
    64741 atgcatttac ataataccat ttaccaccaa cttggaacca ttgattgact ttcatagaac
    64801 cgttgctgtt gaggtagtac catgaaccat taacttgtac ccaacctgtt gccatggaac
    64861 catcagtatt ataaaaatac cacataccat tttcttgttt ccagtctgtt gttggagcaa
    64921 ctgctttagc tggttctact gctacatctg ttccttggtt agatgtaaca gatacaggat
    64981 acgaaggaat agatgattgc tcaggaacaa caactttttc aggttctctc gtccctctcc
    65041 ttatacgtct ttttaccatc tctttagtaa tttgacgaga agtagtttct tcaattattc
    65101 catcacgttc atctacagta tagattgtag taagagtaat ttaccaattt ctcctacttc
    65161 ttctacttct tgacttttat caagagttgg gccatcgaga tattctgttt cgattggaat
    65221 ttcttggaca agaacttggg gcttggttcc ttttttaaca actcttgttt gagagtcttt
    65281 ttttgactta aagtactctc agttacttgt ccactctttc catctacatt ataagttatc
    65341 gttgtaactg ttttcccatt ctttcctaga gtaatctctt gctcctgtcc tgcagaaagg
    65401 tcattgtctg cttcatattt agtagcaaat ggaacaagaa cttcttcaat cttgctttta
    65461 gctggaactt tgataactgt atccgtggct tcttttctat caacagtaac ctgttcggta
    65521 acataaccag tctctggatt aacatcgtag gtccttgtcg tagttacata gccatcctct
    65581 ccgtcaattg taacaggatt ttcactacgg tcttttgttt catctttttc aaaacgaatt
    65641 cgcgtacttg aaattttctt ggttactacc ttaggtttag tcgctacttt tacaataata
    65701 tccccattgt cagcgtcatc atactctatt ccctcttctt tatctctagt atcatctctg
    65761 acatattgaa tcccatcagc agcatgagca aaacttgtat tcagattcct cctaaaaata
    65821 aagttagccc gattatcgca gaaccaaaaa tctttccgag tttacgtatt gcataacgct
    65881 tattagtatt agattttgcc attacatcct acttctagta tagcatcttt tctatcaaac
    65941 gttaaacaat atactttata tataaaatag acttagaatg atatattgat tattgaacta
    66001 acactttaac tatatcgtaa tcaatctcat atataaagga ttgcagacat ctgatctaaa
    66061 tacatgctaa tatatttaga tacaaacatt ccaacttgat aattttcact catctttcaa
    66121 cattccttac acaacgatgc agtataaata gaatagtttt ctcatcagaa tgagactatt
    66181 ttaatattag ataatttgat agaaaaacat aaataaaatt ggttgaattt aattccctaa
    66241 ctcgatagag gattctattt taaatttaac aacagctagg attacactat aaaaagtaca
    66301 ttaccacctg ttcggctgga gaatctagtc gattagctcc ctcttagtta caagcttaaa
    66361 gcgatttttt aactaatact aaaccagatt aaagaaggaa ctagaacatc tgtcttgtac
    66421 taatcaatat gctattttaa aattgcaaat aaacttggaa tgctaattat tatatttaca
    66481 ataaatagtt gacttcgata gaaacagaaa atagaattca acattcttcc ctacttatac
    66541 cataataaat aagatccgca agatagcctt ttctctctac accattaaca atggtttgta
    66601 gataggacat tccagccttt tccatgacac gacctgaagc tgggttgaga ctggcataac
    66661 gtgctctgac cttttgaaaa cctgcttgag taaaacaaaa gtccaagaca gctttcaagg
    66721 cctctgtcat cataccatgt ccccagtaag ccttgcctag cacatagccg atttcacagc
    66781 ttaaatcagc ctcgtctatc ttaacgatgc tgatatctcc tatcacttgc tctgggtttt
    66841 cttttagaca aatggcccat ttgtaatagt tgagattagt ataggaagca acccaattgc
    66901 gaatcgagtt tcgagtgatt tcgacatcag gatggggatc ccaggtaaca taggtcagat
    66961 tctcagtgga tgaagcccaa ttttgaaaca tggcttctgc atcactctcc acaaatcttc
    67021 ttaaaatcaa acgttctgtc tgtaatattt gcgtaccgat agatttcatg atgctacctc
    67081 acttccttat ttctatactc gtagtaagaa ggctcaactc agtaacagct agaaaacgag
    67141 tttgtcttct aatttcttga cgcagttgct gcctggtttg aaatgcgctc tagcaagctt
    67201 tttcaaacct agtcatcgtt gcaggggtaa gacgatgaaa tcgaactctt cgagttactg
    67261 aatctgcctc attttcttat ttctaaactc ggggttcaag atcccccaga ccttctctca
    67321 ctttcttatt tcaagatgag aggctgaaaa cctccactgg aggtttttct tgctttttaa
    67381 tttcagggca agaagctaaa aaggtccccc ggaccttctt cgctttctca tttctaggct
    67441 cagggtaaaa acctccagtg gaggttttta ctcccaaaag tcatcaaata cagtgatggg
    67501 taagtggcgt ttgtgttggc ctttgtgcca ccagttttca atggtcgctt gagcttctgg
    67561 gctgattgtt ttgccttcta ggtagtcgtc aatctctgcg taggtgactc caagtgcgac
    67621 ttcgtcagct aggcctggtt tatcttcttc taggtctgcc gttgggattt tttcataaag
    67681 ggctggctct gcgccaagtt tctgcaagag ctgttttcct tggcgtttat tgaggcggta
    67741 aagagggaga atatccgcac cgccgtcacc aaacttggta aagaaacctg tgatattttc
    67801 cgcggcgtgg tctgttccaa tgaccgctcc gctatgggaa ccagcaaggg catactgagc
    67861 aatcatacgg caacgtgcct tgatattccc cttgttgaag tctgaaacag gactacctgt
    67921 cgcttcaact gcagctgtca tggcatcagc tgattccttg atattcacaa ccaagctgac
    67981 atctggctgg atgaaggcta gggctttttg agcatctgct tcatcagctt gcactccgta
    68041 tggcaggcgg acagcgataa atttgtagct atcgtctccc gtttcagctc gcagttcttc
    68101 catagctaat tgcgccaaac gtcctgccaa ggttgagtct tgtcccccag aaatccctag
    68161 tacaaaggtt tttaggaagg gatgtttttt cagatatctt tttaagaaat caatagaacg
    68221 acggatttct tcctgggcat caatcactgg tttgacaccc agctcttgga taatcgtttc
    68281 ttgcaaactc attcttcttc tccttcacca agggcttcct tgcgcatctt atcaatcaag
    68341 tccatcttat cttgccatac atcacgcgcc aaatccactg gatagtgctg cggattgagc
    68401 acacgcttat actcatccca caacttgtca aattccttac gggcataatc ctgaatgtca
    68461 gtcaaactag gcaagttgta aactaatatt ccttctttga agatatccac caagagagga
    68521 acggcatcaa aattacgaac cgtcttcttg atgtatgtat aggtcggatg gaacatcttg
    68581 atttctgtca tgtcgctaat atccacacca tcataagtga tgtagtcacc ttctgacttg
    68641 cctttttcac gactggtaat gcgccacacc tgcttcttac ctggcgtcga cactttttcc
    68701 gcattattag acagcttaat cgtattgcgc atctggccgt tttcatcttc gattgcaaca
    68761 atcttgtaaa ccgccccaag agccggctgg tcataggctg taatcagctt ggtacccaca
    68821 ccccagacat caatcttggc cttttgcatc ttgaggttaa ggatggtatt ttcatctaga
    68881 tcattagaag cataaatctt agcctctgga aatccagcct cgtccagttg ctgacggact
    68941 ttcttagaaa tgtaggcaat atccccagag tcaatccgca cacccataaa gttaatctga
    69001 tcacccagct cacgcgccac ctgaatggca gctggtacac cgatgcgaag ggtatcatag
    69061 gtatccacaa gaaagacaca atttttgtgg gtcgcagcgt aagccttgaa agcctcatag
    69121 tcattgccat aaacctgtac caaggcatgg gcatgggttc ccaaaacagg aatgtcaaag
    69181 agcttacccg cacgcacgtt gctggttcca ttggcgccac caatcaccgc tgcgcgtgtt
    69241 ccccagatgg ccgcatccat ttcttgagcc cgacgtgtcc caaactccat caagggttca
    69301 tcttcgataa ccgaacgaat acgagctgcc ttcgtcgcca ccaaggtctg gtagttgacg
    69361 atgttcaaaa gagccgtttc gaccaactga cattgggcta gaggtccttc cacctgcaca
    69421 atcggttcat tagcaaaaac caaatcccct tcttgggcag aacgaacggt caactccaac
    69481 ttgaaattgc gaaggtaatc caagaacgcc ccatgataac caagcgactc caaataggct
    69541 atatcactat ctgaaaaacg caagtcttca agatagttca caattctttc caaacctgca
    69601 aaaaccgcat agccgttctt aaaaggctgt tggcggaaat acacctcaaa gaccgccttc
    69661 ttattgtaaa tcccttgatc aaagtaaacc tgcatcatgt tgatctggta caagtccgtg
    69721 tgcaatgtca aactatcatc tggatacata cttttcctac ttccttagct agaaacccat
    69781 gaaaattttc aagaactttc atgtattcca ataaattagt actattatat cacattttag
    69841 ctggattgag aaaagagtaa caagctattc tccactctcc aattcatcca tatcttgttc
    69901 aaattttttc tgagcccatt cgccatagct cttaagacca agattgccaa taaagaccca
    69961 cggaaggtaa atgacataag taatgaccca agcagacagg tatttaaaat tcaaaggatt
    70021 gtgctgataa atttctatgt tgaattgata attctgcaac atcaaaagag ccgtaatagc
    70081 caaggttagg aaaaaacaac ccaaaatcgt aaaatgaaaa cgactatagt aggtcactcc
    70141 cagataacgg gcacgattga aaaagtaaaa tgtccctatg atgataacga ttagcagcat
    70201 attagaatta aaaaggcttg gtgctaatac tgaaatgata taagatagga gcgacaaagc
    70261 aatgcagata tagaaacttt cagagcccgc tttattgaac agttgttctt ctctttcgtc
    70321 tagtaattga taataataaa atctattttt catcttcttc ctcccaaaat agttggtcta
    70381 gggttttccc taaacatctg caaatagact ggcagagcga gagactggga ttgtattttc
    70441 ccgcctctat caaaccaata gtctggcgtg tcaccccgac agcctctgcc agttgacctt
    70501 gtgttaaatc acgctctacc cgagctaatt ttaattttaa atttttagcc accttcgtcc
    70561 tccttatagt tttaatactc atctactctt aaaaaatcca aaaccaacac aagctatcag
    70621 ctatttatta taaccccatt aatttgcact ccagtattat cttcagccga aaatcagtat
    70681 tttaggttgt ttgaaataaa cttcctagtt tactctttta tttttattta gtattagctt
    70741 tagtaggatc ttttaaacga gtttttattg cttatatttc ttgtttagtt tagttggttt
    70801 catatcacta ttatataatg cttttggaaa tgagcctagt ataagtcaaa aacgtgttga
    70861 atagtgaaag caggagcata ccaagatgac tgatttttta ctgtatttta ggtatgcaaa
    70921 ataatactaa atgaaactaa aatgaatact tcttgctttt cttgagagtg aaaaagtaca
    70981 ataaaatgat tgtagtgatt agcacaagat actgactaat agacatcgta tttgaagcca
    71041 caaatacagg taaagaataa aaaggaagaa gttcaattgc tttgataaac aaatcattac
    71101 tagtattcat catcatcgta tttaatatat tagggataaa gagtagtaaa gctactaaaa
    71161 taccaaatac caagccactt ttcaatttgt ataaatagaa aatgtaggat aatagaaaat
    71221 aaaacaggac taacaaaatt gtattgacta caatagctac tataaaatct aatcctaaat
    71281 cacctggaat acccaattta cttactatga ctagtaacac aatgccattc caagcataaa
    71341 taatggaaac tgagatggca tatagaaaat tagacaagac gtaaatcatc cgattcttct
    71401 gttgattata aaacaaactt accgtattgt gggaaaaatc tctactaatg actcgattag
    71461 catgtataac agccattaac ataccgagca tggcataaaa gtttgaaata tgcttaatac
    71521 caagcgatgt cccttgagtc tttagaataa agaatgtaag caatatcggc ggtataaacg
    71581 agataagcaa actgagatat attacgcctg atgaatataa atttcttata ctttccttaa
    71641 gaaaattcaa tttatttaat ttcatgatta taaccttcct ttattttgaa cgatttaggt
    71701 aaatatcttt aagcgtctct tttttagttt caaaatcaac tactttaata gagttttcgt
    71761 taaaaaattt aaaaagctca ctactttgaa tattcccaga catagtaatt ctcagtccct
    71821 cttcctgaac aatatctcca aattcttgtt tggtaatgaa aatgtctcta tctgtagctg
    71881 atgaaaaagc tatctcaaac aagaaattat gactatcttt tcctactttt tgaaatgtca
    71941 aaagcccgct ctccaagaaa agaaccctct cacaaatttc ttcaatatct tctaatttat
    72001 gactcgatat taaaattccc acattttcat gtaaagctaa attttttaga accgctaaaa
    72061 ctatttgtga tgattcaata tctaaaccat tagtcggttc atctaaaatc aatatatcag
    72121 gttccgtaac gagagttaga agcaaagcta atttttgttt tgtacccaaa gaataggtct
    72181 ttactttttt attaatagac tgagtcaaat ctaactcttg gatcaaactt ctaaatcttt
    72241 cttgattgta gtcaacacca tataaatttg acaaatattt taaattctct aaacctgttt
    72301 tagataaaaa taattttggt tcttcgatta aatacccaat attatcactg cttataatat
    72361 tacctgaagt cggttgatta ttctgagcaa gaattttcat caacatactc ttaccaactc
    72421 catttctccc tactagacca acaatttcac ccttgttaag tgcaaaattt atgtctttga
    72481 gaatgattga atgaccataa tgcttactta catttataac ttacattttt tattcctcca
    72541 ttaatattca tggtttgctc tttgattctt attgagttta aaaagttgcg cctcttttta
    72601 acaacattat atcatatatc taacttaatg caatatataa atatcatttt gtaaaatttt
    72661 attaacaaaa aactctctac aacaaaataa tagagagttt tctgcttatt aatttttttc
    72721 aaaatatcta agacatcact tctttgttta atttgatagg ctttgatacc taagctccga
    72781 ctttatcact taaaaaataa aaaaggacag ctaatctctt gcgcatcaag ggatttcgcc
    72841 attctttaat ctcgtttaag tgttgtatat ggagctttgc ataatttttt aaaactaaac
    72901 aactacatta agcacgaact gtgacgctgg ttccatcttc cttataaa
//
LOCUS       DAVKUR010000004        68886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKUR010000004 DAVKUR010000000
VERSION     DAVKUR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.004"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..110
                     /locus_tag="VW749_000318"
     CDS             <1..110
                     /locus_tag="VW749_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0174424.1"
                     /translation="TVSGQWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(589..738)
                     /gene="rpmG"
                     /locus_tag="VW749_000319"
     CDS             complement(589..738)
                     /gene="rpmG"
                     /locus_tag="VW749_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0174425.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(754..936)
                     /gene="rpmF"
                     /locus_tag="VW749_000320"
     CDS             complement(754..936)
                     /gene="rpmF"
                     /locus_tag="VW749_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0174426.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1088..1288)
                     /locus_tag="VW749_000321"
     CDS             complement(1088..1288)
                     /locus_tag="VW749_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0174427.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1291..2298)
                     /locus_tag="VW749_000322"
     CDS             complement(1291..2298)
                     /locus_tag="VW749_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0174428.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2489..4519
                     /locus_tag="VW749_000323"
     CDS             2489..4519
                     /locus_tag="VW749_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0174429.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4523..4807
                     /locus_tag="VW749_000324"
     CDS             4523..4807
                     /locus_tag="VW749_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0174430.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4820..6166
                     /locus_tag="VW749_000325"
     CDS             4820..6166
                     /locus_tag="VW749_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0174431.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            6170..7027
                     /locus_tag="VW749_000326"
     CDS             6170..7027
                     /locus_tag="VW749_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0174432.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7024..7956
                     /locus_tag="VW749_000327"
     CDS             7024..7956
                     /locus_tag="VW749_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0174433.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8189..9892
                     /gene="ilvD"
                     /locus_tag="VW749_000328"
     CDS             8189..9892
                     /gene="ilvD"
                     /locus_tag="VW749_000328"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0174434.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10053..10133)
                     /locus_tag="VW749_000329"
                     /pseudo
     CDS             complement(10053..10133)
                     /locus_tag="VW749_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10191..10532)
                     /locus_tag="VW749_000330"
     CDS             complement(10191..10532)
                     /locus_tag="VW749_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0174435.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10656..11507
                     /gene="rgg"
                     /locus_tag="VW749_000331"
     CDS             10656..11507
                     /gene="rgg"
                     /locus_tag="VW749_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0174436.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11700..12947
                     /locus_tag="VW749_000332"
     CDS             11700..12947
                     /locus_tag="VW749_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0174437.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13025..14314
                     /locus_tag="VW749_000333"
     CDS             13025..14314
                     /locus_tag="VW749_000333"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0174438.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14305..14385
                     /locus_tag="VW749_000334"
                     /pseudo
     CDS             14305..14385
                     /locus_tag="VW749_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14655..14969
                     /locus_tag="VW749_000335"
     CDS             14655..14969
                     /locus_tag="VW749_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174439.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            14979..15185
                     /locus_tag="VW749_000336"
     CDS             14979..15185
                     /locus_tag="VW749_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0174440.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15185..15382
                     /locus_tag="VW749_000337"
     CDS             15185..15382
                     /locus_tag="VW749_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174441.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15385..16119
                     /locus_tag="VW749_000338"
     CDS             15385..16119
                     /locus_tag="VW749_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0174442.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16131..16772
                     /locus_tag="VW749_000339"
     CDS             16131..16772
                     /locus_tag="VW749_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0174443.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16790..17020
                     /locus_tag="VW749_000340"
     CDS             16790..17020
                     /locus_tag="VW749_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174444.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17372..19135
                     /gene="aspS"
                     /locus_tag="VW749_000341"
     CDS             17372..19135
                     /gene="aspS"
                     /locus_tag="VW749_000341"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0174445.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            19113..20054
                     /locus_tag="VW749_000342"
     CDS             19113..20054
                     /locus_tag="VW749_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0174446.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20264..20344)
                     /locus_tag="VW749_000343"
                     /pseudo
     CDS             complement(20264..20344)
                     /locus_tag="VW749_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20480..21466)
                     /locus_tag="VW749_000344"
     CDS             complement(20480..21466)
                     /locus_tag="VW749_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0174447.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21476..22276)
                     /locus_tag="VW749_000345"
     CDS             complement(21476..22276)
                     /locus_tag="VW749_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0174448.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22537..23379)
                     /locus_tag="VW749_000346"
     CDS             complement(22537..23379)
                     /locus_tag="VW749_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0174449.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23381..24673)
                     /locus_tag="VW749_000347"
     CDS             complement(23381..24673)
                     /locus_tag="VW749_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0174450.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24784..26055)
                     /locus_tag="VW749_000348"
     CDS             complement(24784..26055)
                     /locus_tag="VW749_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0174451.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26605..28122
                     /gene="malQ"
                     /locus_tag="VW749_000349"
     CDS             26605..28122
                     /gene="malQ"
                     /locus_tag="VW749_000349"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0174452.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28148..30406
                     /gene="glgP"
                     /locus_tag="VW749_000350"
     CDS             28148..30406
                     /gene="glgP"
                     /locus_tag="VW749_000350"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0174453.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31451..32023)
                     /locus_tag="VW749_000351"
     CDS             complement(31451..32023)
                     /locus_tag="VW749_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174454.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(32646..33494)
                     /locus_tag="VW749_000352"
     CDS             complement(32646..33494)
                     /locus_tag="VW749_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0174455.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33646..33924
                     /locus_tag="VW749_000353"
     CDS             33646..33924
                     /locus_tag="VW749_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174456.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            33926..35989
                     /locus_tag="VW749_000354"
     CDS             33926..35989
                     /locus_tag="VW749_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0174457.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36067..37323)
                     /locus_tag="VW749_000355"
     CDS             complement(36067..37323)
                     /locus_tag="VW749_000355"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0174458.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37465..39930
                     /locus_tag="VW749_000356"
     CDS             37465..39930
                     /locus_tag="VW749_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0174459.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            39995..40906
                     /locus_tag="VW749_000357"
     CDS             39995..40906
                     /locus_tag="VW749_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0174460.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41136..41834
                     /gene="dapD"
                     /locus_tag="VW749_000358"
     CDS             41136..41834
                     /gene="dapD"
                     /locus_tag="VW749_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0174461.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            41902..43032
                     /locus_tag="VW749_000359"
     CDS             41902..43032
                     /locus_tag="VW749_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0174462.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43044..43583
                     /locus_tag="VW749_000360"
     CDS             43044..43583
                     /locus_tag="VW749_000360"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0174463.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43567..44244
                     /locus_tag="VW749_000361"
     CDS             43567..44244
                     /locus_tag="VW749_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0174464.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44316..45215)
                     /gene="galU"
                     /locus_tag="VW749_000362"
     CDS             complement(44316..45215)
                     /gene="galU"
                     /locus_tag="VW749_000362"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0174465.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45237..46253)
                     /locus_tag="VW749_000363"
     CDS             complement(45237..46253)
                     /locus_tag="VW749_000363"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0174466.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46475..46878
                     /locus_tag="VW749_000364"
                     /pseudo
     CDS             46475..46878
                     /locus_tag="VW749_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(46993..47418)
                     /locus_tag="VW749_000365"
     CDS             complement(46993..47418)
                     /locus_tag="VW749_000365"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174467.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(47486..48136)
                     /gene="phoU"
                     /locus_tag="VW749_000366"
     CDS             complement(47486..48136)
                     /gene="phoU"
                     /locus_tag="VW749_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0174468.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48151..48903)
                     /gene="pstB"
                     /locus_tag="VW749_000367"
     CDS             complement(48151..48903)
                     /gene="pstB"
                     /locus_tag="VW749_000367"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0174469.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(48905..49720)
                     /gene="pstA"
                     /locus_tag="VW749_000368"
     CDS             complement(48905..49720)
                     /gene="pstA"
                     /locus_tag="VW749_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0174470.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49713..50576)
                     /gene="pstC"
                     /locus_tag="VW749_000369"
     CDS             complement(49713..50576)
                     /gene="pstC"
                     /locus_tag="VW749_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0174471.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50694..51569)
                     /locus_tag="VW749_000370"
     CDS             complement(50694..51569)
                     /locus_tag="VW749_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0174472.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51736..53067)
                     /locus_tag="VW749_000371"
     CDS             complement(51736..53067)
                     /locus_tag="VW749_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0174473.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMVLTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53068..53775)
                     /locus_tag="VW749_000372"
     CDS             complement(53068..53775)
                     /locus_tag="VW749_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0174474.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(53859..54161)
                     /locus_tag="VW749_000373"
     CDS             complement(53859..54161)
                     /locus_tag="VW749_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0174475.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54148..54369)
                     /locus_tag="VW749_000374"
     CDS             complement(54148..54369)
                     /locus_tag="VW749_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0174476.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54331..54889
                     /locus_tag="VW749_000375"
                     /pseudo
     CDS             54331..54889
                     /locus_tag="VW749_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55204..56895)
                     /locus_tag="VW749_000376"
     CDS             complement(55204..56895)
                     /locus_tag="VW749_000376"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0174477.1"
                     /translation="MNTKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57031..57477
                     /gene="argR"
                     /locus_tag="VW749_000377"
     CDS             57031..57477
                     /gene="argR"
                     /locus_tag="VW749_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0174478.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57528..60062
                     /gene="mutS"
                     /locus_tag="VW749_000378"
     CDS             57528..60062
                     /gene="mutS"
                     /locus_tag="VW749_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0174479.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60209..61903
                     /gene="patA"
                     /locus_tag="VW749_000379"
     CDS             60209..61903
                     /gene="patA"
                     /locus_tag="VW749_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0174480.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62234..62503)
                     /locus_tag="VW749_000380"
                     /pseudo
     CDS             complement(62234..62503)
                     /locus_tag="VW749_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62695..64461
                     /gene="patB"
                     /locus_tag="VW749_000381"
     CDS             62695..64461
                     /gene="patB"
                     /locus_tag="VW749_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0174481.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAHQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPIMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64600..65289
                     /locus_tag="VW749_000382"
     CDS             64600..65289
                     /locus_tag="VW749_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0174482.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65293..65472
                     /locus_tag="VW749_000383"
     CDS             65293..65472
                     /locus_tag="VW749_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174483.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65459..66808
                     /locus_tag="VW749_000384"
     CDS             65459..66808
                     /locus_tag="VW749_000384"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0174484.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            66932..68392
                     /locus_tag="VW749_000385"
     CDS             66932..68392
                     /locus_tag="VW749_000385"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0174485.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68406..68840
                     /locus_tag="VW749_000386"
     CDS             68406..68840
                     /locus_tag="VW749_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0174486.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        20202 a        12817 c        14894 g        20973 t
ORIGIN      
        1 ttacagtttc tggtcaatgg tactatacct ataattcagg agatttatta gtaaacacga
       61 ctacacccga tggctatcga gtcaatgcta acggtgagtg ggtaggatag gtatccatta
      121 gctaaatcta atcattctga actaaaaaat cttcttacat atgtaggaag attttttgga
      181 ttctcaaaac tagtttaaaa gactacgcta tttaaaccaa ttttaagaat ggatatataa
      241 ggatattcag aaatctagtt ggtcaacttt tgtattttga atatacctta gatggtgacg
      301 atgtcttggt atatctggta ctcacttaca tattctaact tattttaact aagatacaac
      361 tgtagttggt gaatttgcta caaatagtgt agaggcgtta tttgaaaaat atacaaaaaa
      421 ggaaccccaa cttacatttg agttcctctt gcttttaatt gtccgaatcc gtattcttat
      481 ttcaataatg tagtcattcg aatgatttcc cttgcaatat agtgaaatta acaaaaagaa
      541 aaaacgctga tcaagcgttt ttcttctgta ttgattcgta ttgaatgctt acttcacttc
      601 tgtaaacaca acgtgtttgc gaagttttgg tgagtatttc ttcaattgaa ggcggtctgg
      661 agtgttacgt ttgtttttag aagtaaggta caagcgttca ccagattctt tgtgttcaag
      721 tgtaatattt acgcgcatag tatctccctt ctattattca gctgatgcag ctttagcgat
      781 tttacgtcct ttgtagtatc ctttaagtga tacacggtga gaacgtgagt aatctccagt
      841 agtttcgtca aagtttacag atggagctgt tactttgtag tgtgtacgac gtttgttttt
      901 cttcgctttt gaagtgcgac gtgcaggtac tgccattttg atttctcctt taggtattta
      961 tattcgattc aatctactga ttttcatcaa ccatactagg ataacacatt ttttttgtaa
     1021 agtaaagtta cttgacaaaa aaagatgaaa aaattctcct atccgacacg gcagacagga
     1081 gaaggtgtta aatatcaatc tcaaatggtt cgtcaatggt ttctgatacg tattttccgt
     1141 cttttttccg ttgcttgaca cactctgtga ggagatattc tatttgccca ttgactgaac
     1201 gaaagtcgtc ttctgcccat gatgcgagtg cagcgtataa ctttgttgag agtcgaaggg
     1261 ggatctgctt ttttttagct tcagccatct ttagtaaaga cttcctgtgt tgacaattgg
     1321 ttgtgcatca tgattgccac aaagaacgac aaggagattt gaaaccatgg cagcttttcg
     1381 ttcttcgtca agttctacca attccccttc attgagccgt tctagtgcca tttcaaccat
     1441 tcctacagca ccatctacaa tcatcttacg tgcatcaata atggcagatg cttgttggcg
     1501 ttgaagcata acggcagcaa tttctggagc ataagctagg taagtgatac gtgcttcaag
     1561 gatttccaag ccagcatcct caacacgact ttggatttct tcacgaatac ggttagcaac
     1621 aatttcgcta gagccacgga gactaccttc atctgcttgc ccgtcacccg tagtatccac
     1681 attaggagac acatcgtaag gatagatgcg gacaatatta cggagggcgc tatcacattg
     1741 caatgaaaga tattctttgt agttatcaac gttgaagact gccttagcgg tatcgacaac
     1801 tctccaagtt accgcgatac cgatttctac agggtttcct aagcaatcat tgattttttg
     1861 acgagaattg ctcaaggtca tgactttgag ggaaatctgt ttcttgccaa tttcaagatt
     1921 tacatcattg tcatttgatg atttagctcc taaaaaagga gattttgtgc taacatcacc
     1981 actttgtcca agtcgagtgt ggtttgcagg gttgactgct acgctgaagg gattgacaaa
     2041 gtaaaaacca ggttctttga tggtacctgt ataattacca aagagtgtca gaaccagagc
     2101 ttcctgaggt ttgacaactt ttaaaccagc atgagctaga cctgcaatta cgattagtaa
     2161 aggtccgata ataattccaa aaatgttttc cgaaccaaca cccattataa atataaagat
     2221 accaagtacg attgtcaatt caatgagaat caatgcgaat acaccatttg gttttgaatt
     2281 gatgagtttt tcagtcataa gaatgacctc ctattatttg atatctaaat gatatcactt
     2341 tgtttttaaa agtcaataga aagttgaaaa taatcactaa aaagtttcag cccaataatt
     2401 tcttttaaaa ggtgagatta tattgtgctc aaatactctt ttattcttat aatttttaca
     2461 ctataattgt agttagaaag gaagagaaat gtttgattat agagcactag ttattttgat
     2521 gactttgatg gatcattgtg agctatcatt atatgaatta tctgttaagg tgagcttacc
     2581 tataaaggaa gtcaaagaag gaatagatta tttagtgcct tatctagcta ataaagggat
     2641 agtgctggat aaaaaacaag gtcgctatag tttatcaaat cgtacgaagc agtctttgac
     2701 agatattatt aagtcggatg aattggtttt accaaagtcg actcgcttag ctttaatcta
     2761 tctttacact ttttgccgat tagattttat atcgaataat cattaccaag actttttgaa
     2821 agtaagtaag aatacaacct tatctgatat tcaatcatta agaaagatta tgttagataa
     2881 tgatttggag ctagggtaca gtagagcaaa aggttatact ttacacggtt cagagtggaa
     2941 taagcaccgc ttagcttttc aaatggttag tgagttgctg gaatcctcca tagggatttg
     3001 gggtttggat tatgttttat ccagttgggg gtattcatta acttatgatt tgataaatca
     3061 ggtagttaaa gattattatg agaagctaca gctagtacct attgttaatc aattaaaagt
     3121 ttgccttttc ggtttagtat tcattctgtg taggtatcaa agggatgttg aaagagtatg
     3181 tctttcagag acattagtat ctcctgttat tcaagatata acgactattt tattggatac
     3241 agtggttgat ttgggaatta tagatacggt gttttctgag gatgattatc gctatatcac
     3301 cgttttatta tcaagttgct ttgaaggtga agtagatgtt gctccggttt actttaatca
     3361 attaacagag gctattataa gtagaatgga agatatttct ttgttacatt ttaaacaaag
     3421 ggaaggattg agagaaaatc ttcgccgcca ccttataccg gcttactata gattaaagtt
     3481 cggcctacct agttcaaatg aatatgtatt gcatgttaaa gaacattatc ctgatttatt
     3541 tgaattagtc aaagattctt tgatgccctt gatggacgct attgacaatc ccatacctga
     3601 tagtgaaaca gcatattttg ttatccattt cggaggttat ttaaagaaag cagatacttt
     3661 gcctcaaaaa tgctataaag cagcaatcat ttgtcctaat ggtgttagtt cttcattgat
     3721 gttaaaagag aatctattag cattatttcc tcaaattgag tttataggaa cctcaaagat
     3781 tgatgattta caggtgaaag ctagtagtga ctatgatatg gttttttcta ccataaaggt
     3841 ggagacagaa aagccaaatt atctagtttc ggttatgatg actgaagagc aagcaataca
     3901 actagtagaa ctagtgttaa aagattttcc gaatttagag tatggggatt ttgagattga
     3961 acaaatcctg aatattgtca aaagatatgg aattattaca caagaattgg aattaagatt
     4021 ggcgttaaag aattatcttt accaaaaaaa tgatagaaag gaaattgtac cagtgctaga
     4081 acaactcatt accaaagaaa cctatcaggt tagttcgcaa aaattaggat ggaaggaggc
     4141 gattcgttta gcagctaaac cgcttttgga tcaagataag ataactgaga actaccctga
     4201 ggcaatgatt caaaaagtag aagagtttgg gccttttatt aatttaggga agggagtagc
     4261 aattcctcac gctcggccag atgaaggtgt gaatgaaata ggaatgtcaa tgttagtttt
     4321 ggaagaaccg atttatttat tggataatcc agaacaagag gtaagattgt tgatttgtat
     4381 tgcagccatt gataatgaga gtcatttaaa ggctttgtca catttaacaa caattttaag
     4441 agataaaaat catgttcaaa ctttaatatc atcaaaaaac tatgatgaca ttaaaatgat
     4501 aattaaacag gaggattaga taatgttaaa aattggtaca gcttgtggtt caggattagg
     4561 ttcaagtttt atggtacaga tgaatattga atctgtattg agtgatttga atgtttcgga
     4621 tgtagaagtt gaacattatg atttaggtgg agcagatcca aatgcagctg atatttggat
     4681 tgttggtcgt gatctagctg attcagctag tcatcttgga gatgttcgta tcttaaatag
     4741 tattattgat atggatgaac tacgagaatt aattactaaa ctttgtgaag aaaaaggact
     4801 tatataggag gctagcgtta tgatgaagtt catattggat attgttagta caccagctat
     4861 tttagtagct ttaattgcaa ttttaggatt agttcttcag aagaagaaat tacctgatat
     4921 tattaaaggt ggaattaaga cctttgttgg tttcttagtt gtatctggtg gtgcaggaat
     4981 tgtacaaaat tctttaaatc catttggtac catgtttgag catgcttttc atttatctgg
     5041 cgttgtgccg aataatgaag caattgtagc tgtagcttta acaacatatg gctcagctac
     5101 tgcactgatt atgtttgcag gcatggtgtt caatatctta atcgctcgtt ttactcgatt
     5161 taaatatatt tttttaacag ggcaccacac tctatatatg gcatgtatga ttgcggtcat
     5221 tttatcagtt gctggcttta ctagcttgcc tcttatctta ctaggaggat tagcactcgg
     5281 tattattatg agtatttccc cagcatttgt tcaaaaatat atggttcaat taactggaaa
     5341 tgacaaggtg gctttaggtc atttcagttc tttgggatat tggttgagtg gttttactgg
     5401 tagccttatc ggtgacaaat caaaatcaac agaggacatt aaatttccaa agagtttagc
     5461 ttttttacgt gatagtactg ttagtatcac tttatccatg gcagttattt acattattgt
     5521 agctatcttt gcagggtcag aatatataga aaaagaaatc agtagtggta caagtggtct
     5581 agtttatgct ttacaattag caggtcaatt tgcagcaggg gtatttgtta ttttagcagg
     5641 tgttcgcctt attttgggcg aaattgttcc agcctttaaa ggtatttcag agcgtcttgt
     5701 acctaattca aaacctgctt tggattgtcc gattgtttat acttatgcac ccaatgcagt
     5761 tctaattgga tttatctcta gttttgttgg tggtttagta agtatggcaa ttatgattgc
     5821 ttcaggaacg gttgttatct taccaggtgt tgtgcctcat ttcttctgtg gagcgactgc
     5881 aggtgtcatt gggaatgcat ctggtggtgt tcgtggagcc actattggag catttttaca
     5941 aggtatttta atcagttttc ttccagtctt tttaatgcca gttttgggag gacttggttt
     6001 ccaaggatca actttctcag atgcagattt tggtctatca ggaattattt taggaatgtt
     6061 aaatcaattt ggctcacaag caggcattgt gattggtctt gttcttattc tagcagttat
     6121 gtttggagta tcctttatta caaagccatc tgcaaaggag gaataaggga tgattttaag
     6181 taaaaatagg gaagatgagt taagaaaatt tgcgactaac atccgattaa atactcttag
     6241 aacattgaat catcttggat tcggacatta cggaggaagt ctgtctatcg tagaagtttt
     6301 agcagtgctt tatggtgaaa taatgccaat gactccagaa atatttgcag cacgagatag
     6361 agattatttc atattatcaa aaggtcacgg aggaccagct ctatacagta cactctattt
     6421 gaatggtttc tttgacaaag aattcttata ttctttaaat acaaatggaa ccaaattacc
     6481 gtctcatcct gatagaaatc taacgccagg catagatatg acaacgggct ctttaggaca
     6541 aggaattagt gttgcaactg gacttgcata tggtcagaga ataagaaaga gtccctttta
     6601 tacttatgct attgttggag atggtgagtt aaatgaggga caatgttggg aggctataca
     6661 gtttgcttct catcaacagt tatccaactt aattgtattt gttgatgata acaaaaaaca
     6721 attagatggt tttacaaagg atatttgtaa tccaggtgat ttcgtagaaa aattttcagc
     6781 atttggattt gaatccatta gggtcaaggg ttcagatatt agagaaattt atgaagggat
     6841 tgtccaatta aaacagtcaa ataattcatc acctaagtgc attgtattag atactattaa
     6901 aggtcaaggg gttcaagagc tggaagaaat gaaatccaac catcatcttc gccctactgt
     6961 agaggagaga caaatgttaa cttcagttgt agaaagatta agtcaggaat tggaggaaac
     7021 agaatgatga gaagcacgaa agaattacgg catgtatata gagacttcct tttagaggct
     7081 aatcaaagtt attctgatat agtagtctta gaagccgatt tgtcaagttc gatggctact
     7141 aataatcttg aaaaggattt tggagaccgt tatgtgaatg ttgggattat ggaagcagaa
     7201 atggtcggcc ttgcagcagg cttgtctatt caggggttta gaccttatct tcatacattt
     7261 ggtccttttg cttcacgaag agtatttgat caattattta tttctcttgg atacgcacaa
     7321 ttggatgcca ctgtgattgg atcagatgca ggagtaactg cagaaatgaa tggtgggaca
     7381 catatgccat ttgaagaaat tggattgtta cgtttaattc ctaaatcgat catttttgaa
     7441 gcaactgatg atatccaatt tcgtgaaata ttgaaccaga cattagactt aaaaggacta
     7501 aaatatattc gaacaattag aaaagctcca gttcctgtgt atcaaggtgg agaagatttt
     7561 tctaagggct acattgagtt aaggcatggt gaagatcttg taatcgttgc ttctggtata
     7621 atggttgctc caagtattcg agttgcagat gaactgtcta aattaggtta ttcagtaagt
     7681 gtgatagatt tatttagaat caaaccgata ccagaacaga taaaaacaat gttaagtgga
     7741 aaaactatat ttactgtaga aaaccacaat cagataggtg gaattggcag ttctttatgt
     7801 gaattattct ctgatgatgg aatgacaaaa attcatcgga tgggtgttca agaaagattc
     7861 ggtcaagtag ggaaaatgga ttatcttctt aatgagtatg gtttgagtga atcgaatata
     7921 aaagagaagg ttctagaaat ttataatgca agatagatgt taaatacact tatctgaaag
     7981 aatttctgta aaaattacag tacgttattt aaagaaagcg gattaaaaag catattctgg
     8041 tcatcagaaa gtgcactaat ccgctttgtt gtttttaatt ttaaatattt cacatgtgta
     8101 tagaattttc tgaaaattca agatttttat tctgttcttc atgcgaaaat tgtgctataa
     8161 tagtaaaaac tgaaatggga gggataagat gactgaatta gataaacgtc accgcagtag
     8221 catttatgac agcatggtta aatcacctaa ccgtgctatg cttcgtgcga ctggtatgac
     8281 agataaggac tttgaaacac cgattgtggg agtgatttcg acttgggcgg aaaatacacc
     8341 atgtaacatt cacttgcatg atttcgggaa actggctaaa gaaggtgtca aatctgcagg
     8401 cgcttggcct gtacagtttg gaaccattac cgtagcagac gggatcgcta tgggaacgcc
     8461 tggtatgcgt ttctctctaa catctcgtga catcatcgcg gactccatcg aggcggctat
     8521 gagtggtcac aacgtggatg cctttgtcgc tatcggtggc tgtgacaaga acatgcctgg
     8581 atctatgatt gctattgcta atatggatat cccagctatt ttcgcctatg gtggaactat
     8641 tgcaccggga aatcttgatg gtaaagatat cgacttggtt tctgtctttg aaggtatcgg
     8701 aaaatggaac cacggtgaca tgacagctga ggacgtgaaa cgtcttgaat gtaatgcctg
     8761 ccctggccct ggtggctgtg gtggtatgta tactgctaat accatggcaa ctgctatcga
     8821 agttctaggg atgagtttgc cagggtcatc ctctcaccca gctgaatcag ctgataagaa
     8881 agaagatatc gaagcagcag gacgtgctgt tgttaagatg ttggaacttg gtctcaaacc
     8941 atcagatatc ttgactcgtg aagcctttga agatgctatt actgtaacga tggctctcgg
     9001 tggttctaca aacgccactc ttcacttgct cgccattgcc catgccgcaa atgttgactt
     9061 gtcacttgag gacttcaata cgattcaaga acgtgtgcct cacttggccg acttgaaacc
     9121 atctggtcag tatgtcttcc aagacctcta cgaagtcggt ggtgtccctg cggttatgaa
     9181 gtacttgttg gcaaatggtt tccttcacgg agatcgcatc acatgtactg gtaagactgt
     9241 agctgaaaac ttggctgact ttgcagactt gactccaggc caaaaagtta tcatgccact
     9301 tgaaaatcca aaacgtgcgg atggtccgct tatcatcttg aacgggaacc ttgctcctga
     9361 cggtgcagtt gccaaggtat caggtgttaa agtgcgtcgt cacgttgggc cagctaaggt
     9421 ctttgactca gaagaagatg cgattcaggc cgttctgaca gatgaaatcg ttgatggcga
     9481 tgtagtcgtt gttcgttttg ttggacctaa aggtggtcct ggtatgcctg agatgctgtc
     9541 actttcttca atgattgttg gtaaaggtca gggagataag gtggccctct tgacggacgg
     9601 acgtttctct ggtggtactt atggtctggt tgttggacat atcgctcctg aagctcagga
     9661 tggtggacca attgcctatc tccgtaccgg cgatatcgtt acggttgacc aagataccaa
     9721 agaaatttcc atggccgtat ccgaagaaga acttgaaaaa cgcaaggcag aaacaacctt
     9781 gccaccactt tacagccgtg gtgtcctcgg taaatatgcc cacatcgtat catctgcttc
     9841 acgcggagcc gtgacagact tctggaatat ggacaagtca ggtaaaaaat aaactcatac
     9901 tcgaaaatct cttcaaatca cgtcaacgtc gccttgccgt aggtatggtt actgacttcg
     9961 tcagttctat ccacaacctc aaaacagtgt tttgggctga cttcgtcagt tctatccaca
    10021 acctcaaaac agtgttttga gctgacttcg tcagttctat ccataacttc aaaacagtgt
    10081 tttgagcaac ctgcggctag ttttctagtt tgccctttga ttttcattga gtatcaaaaa
    10141 gcaagccatt ttcggcttgc ttttttcatc tttaaaagtg attggcctgc ttaacgaggt
    10201 ggtagtccaa gggcaatacg gccatagcga ctgattcgtg tgattttcca agcaggcgac
    10261 caggtaactt caaccttgat atctttgata ccctcgattt gtttcagacc tgccacaatt
    10321 tcaataggca ggctttcggc gcaatcacag gcagtatcgg tgaaggtcat gacaatcttg
    10381 cagagccccg tttcatccag attgatttca taaatcagac ctagattgta aacatccaat
    10441 tccacatctg tatcaaaaac tttctctagt ttttcgataa tttggtcttg caaggccaaa
    10501 gcacggtcat tgattttgat atcgtctctc atagcagtcc ctccacgtga taaatatcct
    10561 ctattttctc ataattctga caatttggca agtttttgat gaattttctg aaaaatagga
    10621 taaaatgaag aaaatacgga atcaagggga agtctatgga gcagattgga aaagtcttta
    10681 gacaattacg agagtcaaga aatatctcac tgagacaagc aaccggagga caattttcgc
    10741 cgtctatgtt gtcccgtttt gaaacaggtc agagtgagct ttcggtggaa aagtttctat
    10801 ttgctctgga aaatatatct gccagtgtgg aggagatcct ctttctggcg agaggtttcc
    10861 agtatgatac agattctgag ttgagaaaag aaattacaga tgtcttggaa ccaaagaata
    10921 tagcacctct tgaggactta tatcgcaggg agtatcaaaa gcatgcccat tctcacaaca
    10981 aacagaaaca tattctaaat gccattatta tcaagtctta tatgaagagc atggatgaaa
    11041 gggtagagtt aacagcagag gaaggaaaag tccttcatga ttatttgttt tctaccgaga
    11101 tctggggaat ctatgaactc aatttatttt cagtcagttc tccattttta tctgtttctc
    11161 tttttactag atatgtacga gaaatggtac gtaaatctga ttttctaatg gaaatgtctg
    11221 gcaatcgaaa cctttttcat actatactat tgaatggctt tttagctagt attgagtgtg
    11281 aagaatttac caatgcctat tattttaaac gtgttatcga agagcatttc tacaaggaaa
    11341 atgagaccta tttccgaatt gtttatctgt gggcagaagg tctccttgat agcaagcaag
    11401 gtagagtcaa ggaaggccag aaaaagatgg aggatgctgt ccgtattttt gagatgcttg
    11461 gctgtaataa atctgccgaa tactatagaa atacgaccga atgttgaata tctgcaaacc
    11521 aagaaaaaat ttgaagcgat agaactattg ccctctctca ggtcattaca aaagttctat
    11581 cgtttctttt tgctcatttt atttgttgca tatattcaag agttctccct ctcaaatttc
    11641 taagtgctat actatagtca tacttcatat agaggttcga acaagaaggg agattatcta
    11701 tgaaactatt gtttagaaat ccagcttata gaattttgat tttatcacgc ttcttcaatg
    11761 cttttggtgc ttcgattttc aacctggtct ttatcgtcta tgcatcgacc ttgtcacaag
    11821 catcttttgc tgttgctatg gcgaatattg tcatgattct tccgaccctc tttacagttt
    11881 ttgtagggat tcgggcagat tacacgaggg acaaggtcaa atggatggtc tatagcggtt
    11941 tgtttcaggc ggttctattt tttctagcag ccctagttgt tcagcaagct agtctctttg
    12001 ccttttctag cctgtgtttg atcaatgtca ttagtgatat catcagtgat tttgcaggtg
    12061 gcctgcgtat gcctcttatt aaggaaaaag tagctgaaga tgatttgatg gaggcttatt
    12121 ctttttcaca gttcatcacc tatatttcag ctattggtgg tcaagctttc ggagtctggc
    12181 tcttagctct atcggtcaac aatttttctc tcgttgcggg aatcaatgcc tgctttttcc
    12241 tagtatcagc cactatcctc tttttaggaa aaagcaaatt gagcctgtca atgtcatctg
    12301 ctgatggtga aaacttaaaa aatgagaagc tttctatcaa agaccagttc ctaacaattt
    12361 accgaaattt acgtctcgtt tttcttaaaa gtgggcagaa aaactttggt tttatgctct
    12421 ttgctgtctt gcttattaat tccttgggtg gcgctttggg tggaatttat aatatcttct
    12481 ttttgagcca ttctctcttg aatttttctt atacagaggc actatttatc aatcaattct
    12541 gtgttttagt agcaatcatc atcagtagcc ttacgggcaa tgattatttt gggaagcagt
    12601 ccttgcctag attgatgatg tgggcgaccg taggacttag tctagttggt ttggctaatt
    12661 tattcaatca agtcgtgctt ggtttgctat ttctcttctt taccctgtat gtgtctggta
    12721 aagttcaacc aaagattagt gccatgctca tgaaaaatct agctccagag gttctagctc
    12781 gtactagtaa ttttttaggt ctattgttta ccttatccat acctgtggga acagcttgtt
    12841 tttcactagt agccgtatgg aatatacagt tgacttggat gctatttgtt ggtctttcct
    12901 tgctagctat ttttttgaca attcttaatc tcaaaaatga tatctaaatc ctaatttttt
    12961 tcttactgtt ttaatccctt tatttgtggt aaaataagac tattaagttt aaagaggatt
    13021 ccctatgaaa ttacaaaaac caaaaggaac gcaggatatt ttacctgctg aatctgctaa
    13081 gtggcagtac gttgagggct ttgcccgtga gattttcaag cgctataact atgcagaagt
    13141 gcgcacgcct atttttgagc attacgaggt tatcagtcgc tctgtcggag atacaacgga
    13201 tatcgtaacc aaggaaatgt acgattttta tgacaagggt gaccgtcata ttaccctccg
    13261 tccagaagga actgcgcccg ttgtccgttc ctatgtggaa aataaactct tcgccccaga
    13321 agtgcaaaag ccaagcaagt tctactatat gggacctatg ttccgttatg agcgtccaca
    13381 ggcagggcgc ttgcgccaat tccaccaaat tggtgttgag tgttttggct ctagcaatcc
    13441 agctaccgat gtggaaacaa tcgctatggc agcccatttt ttgaaggaaa tcggtattca
    13501 aggtgtcaaa ttgcacctca acactcttgg aaatcctgag agccgtgcag cctaccgcca
    13561 agccttgatt gactatttga caccgctcaa ggagaccttg tctaaggata gccaacgtcg
    13621 cttggaggaa aatcctcttc gtgtcttgga ctctaaggaa aaagaagaca aggaggcagt
    13681 agagaatgcg ccgtctatct tggactttct tgatgaagaa agccaagctc attttgatgc
    13741 tgtgcgtcag atgttggaaa atcttggagt agattacatc atcgatacca atatggtgcg
    13801 tggtctggac tactacaacc acaccatttt cgagtttatc acagagattg agggcaatga
    13861 cctgaccgtc tgtgcgggtg gtcgttacga tggtttggtt tcttattttg gaggccctga
    13921 aactgctgga tttggttttg gacttggtgt agagcgcctg cttctcattc ttgaaaagca
    13981 aggtgtgacc ctccctatcg aaaacgccct agatgtctat atcgcagtct tgggcgaagg
    14041 ggcaaatatc aaggccttgg aattggtaca ggctcttcgc caacaaggtt tcaaagcaga
    14101 gcgtgattac ctcaaccgta aactaaaagc tcagttcaag tcagccgatg tctttgtggc
    14161 taagaccctc atcaccctag gagagagcga agtcgaaagc ggacaagtga cggtcaagaa
    14221 caaccaaact cgagaagaag tgcaagtgtc acttgagaca atcagccaaa acttctcaga
    14281 aatctttgaa aaactaggat tttatactca ataaaaatca aagagcaaac taggaagcta
    14341 gccgcaggtt gctcaaaaca ctgttttgag gttgtggata gaactgacga agtcagctca
    14401 aaacatggtt ttgaggttgt agatgaaact gacgaagtca gtaaccatac ctacggcaag
    14461 gtgaagctga cgtggtttga agagattttc gaagagtatt aatgatagat aaagtggtca
    14521 ggaacttact cctgaccttt ttcttttgca aaatgacaaa aatcataaac tttttgacaa
    14581 atatacttgt caaaaagaaa aagatatgtt acaatgaatt caagttaaga aataggaagc
    14641 agaaaggagt tataatgtgg gtactaggat ttatactatt tatgattttc ttttattcta
    14701 ataattctaa aaaaatcaag aaactagaga ataaaatcaa aaaacttgag cgaaaagaga
    14761 aaggaaacgc agaaatgtcg agattattac aagaaatgat tggaaaggaa ccaattataa
    14821 cgggagtgta tattgggcca gataactggg aagttgtgga tgttgatgag gaatgggtca
    14881 aactacgtag tgttgataat acgggaaaag aaaaattcaa gttgcaacgt attgaagata
    14941 tccaaaccgt tgaatttgac ggagagtagg tgtgtaacgt gcaactaaaa aatcgtctaa
    15001 aagagcttcg agctcgcgat ggtctcaatc aaaccgacct agccaaactg gcaggggttt
    15061 ccagacagac cattagccta ctagaacggg atgagtacac cccatccatt atcattgccc
    15121 tgaaaatatc tcaaattttc aacgaaacag tcgaatcggt atttcgtttg gaggaggacg
    15181 agtgatgaac aagtataaag tgatttatta tgtagtggtc atagctttat tagtcagcgt
    15241 atttctactg attgggatgg acctaagctg gtttaatccc tatcaaggcg accaatttgt
    15301 ttggctctac tttgctctca tcccagtaat tgaatggatt gaaaagaaat ccaaaaatct
    15361 agcaagtgaa aaaggagaat gaatatgaaa aagaaacgta gattgttatt tttgatgtct
    15421 attgtcttgg gggggttctt gggcatgttt gtagggatgt ttaaggcacg tgtcgaatcc
    15481 cacgaaatta ttttagatgt aaaagccttg atgccatgga tatcagctat ttgtttactg
    15541 ataggtttca ttagtatgtt tttgactttc aatttcttaa agaaaagcag aaaatttcat
    15601 tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa cctattatgt gcaaatgtat
    15661 cggaatcttg agtttggaac cattgctttt aatattacag gtgtagcgat tccattggct
    15721 atttttattt cattaagtga ggtgattata ttgcatacaa accctcaaac atttttcctt
    15781 tctttcttac tctttgtggt attcttagtc gctcaaaaat ctctttttaa aaccattgcg
    15841 attgttcgtc agtttgattt ggaatttttc gctacaccaa aggatgtctt gaactatata
    15901 aattcttatg atgaagggga gcgtcaggct aatttggaac agagttttcg aattttattc
    15961 caattacacc aatatgtctt accagcctta tatatttttc ttattatcat ttctttcttg
    16021 acaggagaga ttcagttact agctttcttg cttgtaggag ccatccatgt ttatatcaat
    16081 gtgatgcagt tacctatggt aaaacgttat ttcaaataaa ggagttatct atgaaattac
    16141 ttaaaaacct tggctggatt cttctagccc ttctatcctt tttatttatc tatggcttta
    16201 ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc accctatgct gttactctac
    16261 tctatgtggc cttggctgga gtatatgtgt acggcattta caaatggtat cagaaggctc
    16321 ctgttcatat tgagaagagc ggctttaacc gatttatttg gcttcctgcc ttggtttggt
    16381 tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc ttcagtaaat cagcaaatag
    16441 cgacagactt gaccttgtct caaccacttt tctcattctt tgctgtggtt atttttgctc
    16501 ctttgacgga agagattgtt tttagaggga tgttagcacg ctatctcttt cctaagcagg
    16561 acaatagtaa acgaaccctg atttttcttc tggtatctag tcttctattt gccttgattc
    16621 attttccagg tgatgtgcaa caattttttg tctattttag ccttggtttt agtttgggct
    16681 tggcttacat tagcagaaaa ggtctggtct acagtatttc tcttcacgct ttgaataatt
    16741 tagtcggctt tttgatgatt ctcatgctat aatagagtca ggaggtcaca tgaaacgagt
    16801 aattttatta gcagtgattc aggcagtcgt tctatttttc atcattggag cgctagctta
    16861 tgccttcaaa ggcgatttct tctataacta tctagcagtt gtctttgctc ctattgcagg
    16921 tgtactgcgt tttgggacgg cttacataac ggaaattgtc ttgcctcgaa aggcagccga
    16981 aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa aagagtccgg tgaagttcat
    17041 cggatttttg tattatactc aatgaaaatc aaagagtaaa ctaggaagct agccgcaggt
    17101 tgctcaaaac actgttttga ggttgtagat gaaactgacg aagtcagctc aaaacatggt
    17161 tttgaggttg tagatgaaac tgacgaagtc agtaaccata cctacggtaa ggcgacgctg
    17221 acgtggtttg aagagatttt cgaagagtat tagcgctaat ttttagggct ttcacttgac
    17281 ttttaaagac tggcaaactt ttctgatgat tttcatgaag agcctgcgct tttatggtaa
    17341 aatagtaaca gaataaaaga ggagagaaat aatgaaacgt agtatgtatg ctggtcgtgt
    17401 tcgtgaggaa cacatcggac aagaaataac cttgaaagga tgggttggcc gtcgtcgtga
    17461 ccttggtggt ttgatcttta tcgatcttcg tgaccgtgaa ggaatcatgc agttggttat
    17521 caaccctgaa aaagtatctg cagaggttat ggcaacagct gaaagccttc gtagcgaatt
    17581 tgttattgag gtgactggtc aggtcgctgc gcgtgagcaa gccaatgata agttgccaac
    17641 tggtgcggtt gagttaaacg tgacagctct tattgtgctt aacacagcta agacaacacc
    17701 atttgagatt aaggatggca ttgaggcaaa tgacgataca cgtttgcgtt accgttacct
    17761 tgaccttcgt cgtccagaaa tgttggaaaa tcttaaactt cgtgccaagg tgacccactc
    17821 tatccgcaac tatttggatg agttggagtt tatcgacgtg gagacaccat tcctttctaa
    17881 gtcaacgcct gaaggggcgc gtgattattt agtgccgtct cgtgttaata aggggcattt
    17941 ttacgctctt cctcaaagtc cacaaatcac gaaacagctc ttgatgaatg ctggttttga
    18001 ccgttactac caaatcgtta aatgtttccg tgacgaggac ttgcgtggag accgccagcc
    18061 tgaatttact caggtcgact tggaaacgtc cttccttact gagaaagaaa tccaagatat
    18121 tacagaaggc ttgatcgcgc gcgtgatgaa ggaaacaaaa ggcatcgaag taacgctacc
    18181 gttccctcgt atgaaatacg atgatgctat ggctctttac ggttctgaca agccagatac
    18241 tcgttttgac atgttgcttc aggacttgac agaagtggtc aaaggtgtag actttaaagt
    18301 cttttcagaa gcacctgctg taaaagcgat tgtggtcaaa ggagctgcgg acaactattc
    18361 acgtaaagac atcgacaaga tgacggaagt agccaaacag tatggtgcca aaggtcttgc
    18421 ttgggtcaag gtggttgatg gagaattaaa cggaccagtt gccaagttct tgactggtat
    18481 ccaagaagaa ttgacaacag cgcttgctct tgaagataag gacttggttc tctttgtggc
    18541 ggatacgctt gaagtggcta atgcaacact gggtgccctt cgtggacgta ttgctaaaga
    18601 gcttggcttg attgataatg ataagttcaa cttcctttgg gtggttgact ggccgatgtt
    18661 tgaatggtct gaagaagaag gccgctacat gagcgcccac catccattca cacttccaca
    18721 ggaagagact gctcacgaat tagaaggtga tttggctaag gttcgtgcca ttgcttacga
    18781 tatcgtcttg aacggttatg agcttggtgg tggtagcctt cgtatcaacc aaaaagacct
    18841 tcaagaacgc atgttcaagg ctcttggttt ctcaactgaa gaagccaatg accagtttgg
    18901 tttccttctt gaagccatgg actatggttt cccaccacac ggtggtttgg ctatcgggct
    18961 tgaccgtttt gtcatgttgc ttgctggaga agaaaatatc cgtgaagtca ttgcctttcc
    19021 taagaacaac aaggcaactg acccaatgac acaagctcca tcaacagtcg ctctcaaaca
    19081 actagaggaa ctcagcttac aagtagaaga agatgaaaca aacaaaacga attaagcggt
    19141 ggcgctatta tctgcgccgc tttgcttatc agataaaaat tttacgtgtc ttacaaagta
    19201 tctctcgaga aaagtatgat gagaagattt cggcctctct ggtctatggt tttttatcag
    19261 cagtagcagt taatttcttt ttccaaccag ggcatgtgta ttcgagtggt gcaacaggtc
    19321 tggcacagat tatctctgcc ttgagtaatc actggtttgg ttttcatatt ccgatttcgc
    19381 taagcttcta cgccattaac ttccctttga tggtcttagc ttggtatcag attggccata
    19441 agttcaccgt ctttaccttt atcacggtat ctatgagttc cttctttatc cagtttgtcc
    19501 ctgtggcaac cttgacggag gatcccatta tcaattccct ttttgggggt gttgttatgg
    19561 gtttggggat tggttttgct cttcgaaaca atatctccag tggtgggacg gatatcgtca
    19621 gcctgactat tcgcaagaaa acgggtaaga atgtcggtag tatttctttc ttggtaaatg
    19681 gaactatcat gctgatagca ggtttgacct ttggttggaa atacgctctt tattctatga
    19741 ttaccatctt tgtctctagc cgtgtgacag acgcagtctt tactaagcaa aagcgtatgc
    19801 aggccatgat tgtgacaaat catccagaga aggtaattga aaaaatccat aaaaaattgc
    19861 accgcggagc aaccatgatc cacgatgcag aaggaaccta taatcacgag agaaaggcag
    19921 ttttaatcac tgtcattaca cgtgcagagt ttaatgaatt taaacagatt atgacacaag
    19981 tggatccaag ctcctttgtc tctgtctcgg aaaacgttca tattctagga agatttgttg
    20041 agatagataa ttagtgatta atactcttcg aaaatctctt caaaccacgt cagcttcacc
    20101 ttgccgtata tatgttactg acttcgtcag ttctatctgc aacctcaaaa ccatgttttg
    20161 agctgacttc gtcagttcta tctgcaacct caaaaccatg ttttgagctg acttcgtcag
    20221 tttcatctac aacctcaaaa ccatgttttg agctgacttc gtcagttcta tccacaacct
    20281 caaaacagtg ttttgagcaa cctgcggcta gcttcctagt ttgcactttg attttcattg
    20341 agtataaaaa gatcttggga aaagactcaa tttcagtaga aaaggaagta aatcttccca
    20401 caataaaacg catagtatca agttttttca atacctgata gtatgcgttt ttgcttttaa
    20461 cgactctttg cccagtctct tatttttcga taattttgtg ggcgatcaat tgacggtaac
    20521 aaatttgttt attgttttta ttatcattaa taatctggag aatagtttca agggaaacac
    20581 gaccaagctc taaactattg atatcgacat aggctgccaa gttgagcttg ggattaaccg
    20641 agtcaaagct gagaacaggg acatccagct ggtgtttggc aatatagtta caaacacctt
    20701 cagctaggag gctatcggtt gtgatgatag catcaatttg tggatcgtgc ttgaataatc
    20761 gcttgctaaa tttatagccc ttttcttcca gaaactcgtc ggcaaagtag atgcgattgt
    20821 tgtcagtggt aagtttgtaa tgtttaagcg cctgttcata gcccgttaaa cggtctttgg
    20881 tcacgaagag ctttttactt cctccgataa aggcaatgcg tttgcagcct tttttgatga
    20941 aatattcagt cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt gggatgaaag
    21001 gagatagaga tttacctaag ataaggaagg ggaactgttc ttctgcgacg agttttacga
    21061 gagggtcttc ttcttgggca tagagaaaga ttagcccatc tacacgcttg ccgtagacca
    21121 tttgtgaaat agcgttgaga cgctccttct catctttccc tgttgctatt tgaatggcat
    21181 agtggttttc agatgcgact tgagagatgc cacgtagaac cgatggaaag aaaggattct
    21241 ggtagaaggc gtctgagtca tcaggaagaa ctaatccgat aacctgagta tagctgctta
    21301 ccaagctacg agcgttaagg tttgggtggt agttgagttc cttcatagct ttgcgaacgc
    21361 gtttttttgt ttcgtcgcta atggttgatt tattttgaat aacacgggtt acggttgaag
    21421 gcgaaacacc agcagccttg gccacgtctt taatcgtaac gggcataaaa atctcctatt
    21481 tatggtaatt tggatcacgg aaatgtgttt tataaaagat agtgaccaga tacagaacaa
    21541 aaagaatatt ttgtacagta atcagggttg tcatattttg gccaaataat cccaaaataa
    21601 gtgtaatcag agtcggcaat cctaaacagt tcaagataaa gtgatagcac tctttaaagg
    21661 ttctaaatga aaagaggcgt gatttcttag tgatataaag gagaagacta gctcctagag
    21721 agacgataaa gaaattcaaa ccaaagagga agctcgcacc gagaactagg aagaggctga
    21781 tatagacacg attttgttgg taccagtctt tagaaattgc ttgggtcaag ctgtctttgc
    21841 ttttgaaact ctcagtctga atggctcggt aagagatgcg ggtcagttcc ttgctttcct
    21901 tgctgatgac tagttcattt gtatcgaaat gcagttgcaa gtccttaggt aattccttga
    21961 tttgacctgg accaatcaca acagaagggg cttgactagc tgttccagta taagttaatg
    22021 tgccatcgac aattgtagca tgttcagaga gatcctggac aacctcattt gtcagaggtt
    22081 catagacatt atcgataaaa gtttctagcg gataggtctc ctgggagctg ttttggatag
    22141 caatgggtac catagacaag ctgataagga agatactggt aaagagaagt tgaaaccagt
    22201 tgagctcgaa acgtttggac aggggcttac gaaaccccca aatacttgaa aaataggaaa
    22261 atggatatgg aagcataggt atctttctaa aaggtgtttt ctatatgagt attattatat
    22321 agagaaatgc gctttatttc aagtctaggg ggtaaattgc ttgctacaag gatattattt
    22381 acagtgacaa tcgctaatag tcaatgaaaa tcaaagtgca aaccaggaag ctagctgcag
    22441 gttgctcaaa gcacaacttt gaggttggag ataaagctga cgtggcttga agagattttc
    22501 gaagagtata aaatgaaaaa gggtggcggg gataaattat cccttgtcgc caccacttgt
    22561 aagtcctgaa acaaagttct tttgtaggaa gaagaagaga atacagattg gaagggcgat
    22621 gaggatagca cctgctgaga agtaggcaat cttcaagttt ttcgcattgt taacgaaggt
    22681 ttggagacct acggcaacag taaagtattc tttctcacga agcaagaaac tagagaggat
    22741 gtagtccccg aaaggtccca tgaaggccca gagagcttgt acggcaacca ttgggcgaac
    22801 aagtggtaga acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta gttttgcaga
    22861 ttcgtctaaa gacattggca ctgtatcgaa gtagcctttc atgagccaag cattcatcgg
    22921 gataccacca ccaacgtaga ggaagatgag gaaccagttg tggttaaggg cgttcaacat
    22981 aagcgccata acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt ggatgatcaa
    23041 gaagaagacc aaactttgtt tacgagccaa gaagttgtaa cggctgtaag cataaccagc
    23101 aagtacgatg atacttgttt gaacagccat ggtaattaag gcgataatca aagtgttgag
    23161 gtaccaagta ccgtacaagg tttcagtgaa gaggccttta aagttatcaa aattgaggtc
    23221 gatattagta tctagtttaa aggctgagac gttacctgct ttaaaggctg acatgatggt
    23281 aatcaacagt ggatagataa ttacaattga tagaccaatc aggtaaaggt aagtaaggct
    23341 ttgagtcagt ctacgtttga gtttaattga gttattcatc ttagacgtcc tccatatcaa
    23401 atgcgtgtag tttcttgaat gcgatcatag agattgagat gacaatgata gagataatca
    23461 aggtaacagc tgccgccatt gagtattgag gagatgtacc tgttgtcaaa cggtagatcc
    23521 atgagatcaa gatatcggtt gaaccagctc cacctccgac actaccaggt cctccaccat
    23581 tgaagaggta catgatagag aagttgttaa agttgaaggt gtattggcta atcaaagtag
    23641 gtgccgcaac agccaaaatc attgggaaag tgatgttgcg gaatttttgc caagcgttgg
    23701 caccgtcaat ataagctgct tcgtaaaggt cgttaggaat agattgcaag atacccaaag
    23761 tcaaaacgta gatgtatggg aatccgagcc aaccttgcat cataatcaag gcaatcttag
    23821 tccaagttgg gtctgttttc caaggaataa gagctccatc aaggaaagga aggaatttag
    23881 ccaagattgg caatacttga gtgttgatag caccgacact atcgttaaac atgtttgaga
    23941 atgtcaagat agtgatgaag gctgggacag cccaaggaag aaggaaaata acaccaaaga
    24001 tacgttttcc tttgataaat ggttggttgg caatgatagc tgtgaagata ccaattacga
    24061 tttgtaaagt agaagctgcc aaagcccaaa tgatagtcca agaaagaaca gaaccaaagg
    24121 cagaacggaa ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca acccagtcca
    24181 acaacttgtt tggtggcaag tgttggaagt cgtagttggt aaaggcgatc atcaaggtta
    24241 cgataactgg gaagataatc gcgaaggtca tggcaacata agatggaatg atcaagaggt
    24301 aagggaagcc attttcataa atccctttga tcatgtcttt gagtgtgcgt ggaactggaa
    24361 ttccattgtt aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag aaataaaaga
    24421 gtacataaac gattacaaag attagatgga aggcaccacg aatcagcata aagagggaat
    24481 tatcacgacc tggtttgtca ccaagagtga tgaggttgct caattcaggg gttgcaagtg
    24541 ctaggaagta aaggacaaat acgatggtta caccaaggaa gataaaacct ttggcttttt
    24601 gtttattgta aatctgtcct aacccaggaa tgatagacag cagggctgct ttactaggtt
    24661 gttgcttttc catattaact cctttcatag gatactactt ttttataaga aagctaaatt
    24721 atttgtgtct ctattgataa attcaaaggg ggatttgatt tccacccccc ttgaacaaat
    24781 tttttattca ccaaattttt gtttgattgt ttctttgatc aatgttacag catcgttagc
    24841 agctgtttta gcatcttttt gaccacttac agcatcaaag agcatatttt tcgctggatc
    24901 ccaaactgca gacatttgag agatgtttgg cagtggttga gtgttcttga actgtttgat
    24961 aacagctgtt gtcaactcat cgtttttacc ttcagcgtat gaacgagcct cagtattagc
    25021 tgggatttcg ttagtcttat catataatac tttttgttgt tcagttgcaa caaggaagtc
    25081 tacaaatttt tgagaagctt caaggttctt aacggcttga ggaatgaccc aagctttacc
    25141 accaccgaat gcagcatatt cttttccatt tggaagagtt gggatagttg caactccgta
    25201 gtttacttta gcatctttaa aggcttgagc tttccaaggt ccgtcgatga tagcagctgt
    25261 tttaccttct tggaattgag tttggattaa gtttccagca ccttctgtat cttgcatacc
    25321 tttaggccat ttttcgtacc aagatttagc gtagttgata cctgcgatag aaccgtcgtt
    25381 tgcaagaccg atgtctttag cgtctttacc gttttggcca aagacgtaag caccgttacc
    25441 ggcaagaagt ccatatgtat agtagaagtt tgtccagtca gctaggaagg cagtagtttt
    25501 accatcttca ccagcgaatg cgtatttgct atctttagca aggttttcca agtcagcaaa
    25561 tgtttttgga gcatctttca ccaagtcttt gttgtagtac ataacaagtg actcgataac
    25621 ggcaggagca ccgtaaactt taccattagc agctgttaca agagatttag ttgtgtcgtc
    25681 tgttttagca ccatcgctca atttcacttc tgaaagttgt ccgtcagaac caaggctacc
    25741 tacacggtcg tatggagcca tcataacatc agggacatta ccagattggt tgtcaagaga
    25801 aagtttatca agacctccta gagcatcacc agttttaaga gtgactttta ctccagcttc
    25861 tttttcataa gctttagcaa cctcttcaat atagctctta tatccctcgt ctacatatac
    25921 agtgagttct ttgacttcag atgaaccaga atcagcaggc ttatcagcag ttttgcttcc
    25981 gcaagctacc aaaagcaagc tagcaagtgt agcagttcca agcaccgcag tgctcttcat
    26041 aaatttagat gacatagtgt attcctccca aagaatagca agttttattg ataaggaaac
    26101 gcaaacgttt tcctttatga gcttagtata gcacaaatag aaaacggttg caagtatttt
    26161 ttgtaaaaat tttaaaaaat ttttaagctt gatttgatag cataattttg cattttaata
    26221 gaagaaaagt atgaaataga taagaataca gtatttttaa taaaaatata tggaatctgt
    26281 ctaaagaggg aaatcaggag gggctacctc cctgtttcta atccctatct attttctata
    26341 gacgtttgtg ctttgttgca tataaattca agctccctaa ggaggttttg tactttgtag
    26401 actgtctcgt gagagtcaaa ctttaggatt agatagtttt aagttatctt tgctaaaatg
    26461 agttagtctc cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa ttatgcttga
    26521 aaaggagtat acttataagt aacgcaaacg tttgcgtctg caaaatacgc aacgttccat
    26581 tattttaaca cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt gatgcacatc
    26641 tcttctcttc caggagctta cggaatcgga tcatttggtc aaagtgctta cgacttcgtt
    26701 gatttcttgg tccgtacaaa acaacgttac tggcaaatcc ttccattagg agcaactagt
    26761 tacggggatt ctccttacca atctttctca gccttcgcag gaaacactca ttttatcgat
    26821 ttagatatct tggtggagca aggtttgttg gaagcaagtg accttgaagg agttgacttt
    26881 ggtagcgatg cgtctgaagt tgactatgct aaaatctact atgcacgtcg tcctctttta
    26941 gaaaaagcgg tgaaacgttt ctttgaagtc ggagatgtta aagattttga gaaatttgct
    27001 caagacaacc aatcatggct tgagctcttt gctgagtata tggctatcaa agagtatttt
    27061 gacaatcttg cttggactga atggccagat gcagatgctc gtgctcgtaa agcttcagca
    27121 cttgaaagct atcgtgagca attggcagac aagttggttt accaccgtgt gactcaatac
    27181 ttcttcttcc aacaatggtt gaaattgaaa gcttacgcta acgacaacca catcgaaatc
    27241 gttggggaca tgccaatcta cgtagcggaa gattcaagtg atatgtgggc aaatccacat
    27301 ctcttcaaaa cagatgtcaa tggtaaggct acttgtatcg caggatgccc accagatgag
    27361 ttttctgtaa ctggtcagct ttggggtaat ccaatctatg actgggaagc aatggacaaa
    27421 gacggctaca aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta cgatatcgtt
    27481 cgtatcgacc acttccgtgg cttcgaatct tactgggaaa tccctgctgg ttccgataca
    27541 gcagcacctg gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc cgttaaggaa
    27601 gaacttggtg agctaaacat catcgcagaa gaccttggct tcatgacaga tgaagtgatc
    27661 gaattgcgtg aacgtactgg cttcccagga atgaagattc ttcaatttgc cttcaaccca
    27721 gaagacgaaa gcattgatag cccacacttg gcacctgcta actcagttat gtacacagga
    27781 acacacgata acaatacggt tcttggttgg taccgtaatg agattgatga tgcgactcgt
    27841 gagtacatgg ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca cgctatgctt
    27901 cgtacagtat tttcatcagt tagctttatg gcaattgcaa ctatgcaaga tttactagaa
    27961 ttggatgagg cagctcgtat gaacttccca tctacccttg gtggaaactg gtcttggcgt
    28021 atgactgaag atcaattgac accagctgtc gaggaaggtt tgcttgactt gacaacaatt
    28081 tatcgccgaa ttaatgaaaa tttggtagat ttaaagaaat aagacaataa tcaggagaca
    28141 actaaacatg ttatcactac aagaatttgt acaaaatcgt tacaataaaa ccattgcaga
    28201 atgtagcaat gaagagcttt accttgctct tcttaactac agcaagcttg caagcagcca
    28261 aaaaccagtc aacactggta agaaaaaagt ttactacatc tcagctgagt tcttgattgg
    28321 taaactcttg tcaaacaact tgattaacct tggtctttac gacgatgtta aaaaagaact
    28381 tgcagctgca ggtaaagact tgatcgaagt tgaagaagtt gaattggaac catctcttgg
    28441 taatggtggt ttgggacgtt tggctgcctg ctttatcgac tcaattgcta ctcttggttt
    28501 gaatggtgac ggtgttggtc ttaactacca ctttggtctt ttccaacaag ttcttaaaaa
    28561 caaccaacaa gaaacaattc caaatgcatg gttgacagag caaaactggt tggttcgctc
    28621 aagccgtagc taccaagtac catttgcaga ctttactttg acatcaactc tttacgatat
    28681 tgatgttact ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg acttggattc
    28741 agttgattct tctattatta aagatggtat caactttgac aagacagata tcgctcgcaa
    28801 cttaactctc ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc tccgtatctt
    28861 ccaacaatac ttcatggttt caaacggtgc gcaattgatc atcgacgaag caatcgaaaa
    28921 aggaagcaac ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg atactcaccc
    28981 atcaatggtg attcctgaat tgattcgtct tttgactgca cgtggtatcg agcttgacga
    29041 agcaatctca attgttcgta gcatgactgc ctacactaac cacacaatcc ttgctgaggc
    29101 gcttgaaaaa tggcctcttg aattcttgca agaagtggtt cctcacttgg taccaatcat
    29161 cgaagaattg gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc aaatcatcga
    29221 tgagagcgga cgtgttcaca tggctcacat ggatatccac tacggataca gtgttaacgg
    29281 ggttgcagca cttcatactg aaatcttgaa aaattctgag ttgaaagcct tctacgacct
    29341 ttacccagaa aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt ggcttatgca
    29401 tgctaaccca agattgtctc actacttgga tgagattctt ggagatggtt ggcaccatga
    29461 agcagatgag cttgaaaaac ttttgtctta tgaagacaaa gcagctgtca aagaaaaatt
    29521 ggaaagcatc aaggctcaca acaaacgtaa attggctcgt cacttgaaag aacaccaagg
    29581 tgtggaaatc aatccaaatt ctatctttga tatccaaatc aaacgtcttc acgagtacaa
    29641 acgccaacaa atgaacgctt tgtacgtgat ccacaaatac cttgacatca aagctggtaa
    29701 catccctgct cgtccaatca caatcttctt tggtggtaaa gcagctccag cctacacaat
    29761 cgctcaagac attatccatt taatcctttg catgtcagaa gttattgcta acgatccagc
    29821 agtagctcca cacttgcaag tagttatggt tgaaaactac aacgttactg cagcaagttt
    29881 ccttatccca gcatgtgata tctcagaaca aatctcactt gcttctaaag aagcttcagg
    29941 tactggtaac atgaaattca tgttgaacgg agctttgaca cttggtacta tggacggtgc
    30001 taacgtggaa atcgctgagt tggttggaga agaaaacatc tacatcttcg gtgaagattc
    30061 agaaactgtt atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat tctacgctcg
    30121 tgaagctatc aaaccattgg ttgacttcat cgttagtgat gcagttcttg cagctggaaa
    30181 caaagagcgc ttggaacgtc tttacaatga attgatcaac aaagactggt tcatgactct
    30241 tcttgacttg gaagactaca tcaaagtcaa agagcaaatg cttgctgact acgaagaccg
    30301 tgacgcatgg ttggataaag tcatcgttaa catttctaaa gcaggattct tctcatctga
    30361 ccgtacaatc gctcagtata acgaagacat ctggcacttg aactaatact cttcgaaaat
    30421 ctcttcaaac cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag caacctgcgg
    30481 ctagcttcct agtttactct ttggttttca ttgagtataa gatacaaatt tatactaata
    30541 cattttgtaa aaaagcgagt ttcgattgaa attcgctttt ttaaatgctg tagatttggg
    30601 tcaatcttgt ctaaaaatag ggaaatccta gatacagtga agactttaaa tgctggtttt
    30661 tactgtcctc agccttatat tttttcgtag ttgattacct cacacctctt gtattcgctt
    30721 acataaagta ttataatata attgtaggaa agaaggtgtt tttatgatat acacacttaa
    30781 attggtgttg tttattacct ttcttgtaat aagcttgtta cctgataaga tttttggaaa
    30841 aaataaaaaa atttggaaaa tagtttttgc aatattgacg gcagtggcag cattgtcatt
    30901 tatgtactaa gttattttaa gaatgtaggg aaataaaccc tacattcttt ttagtttttt
    30961 ctgttttcta aattctattt atccaagcgc ttcaacattt cttgcttctt cgcttcaagt
    31021 tctgcacgct tttcttcgat ttcggcatgt tttttctcga gttcagaaca acttgcacca
    31081 ttgctaaatt cttttcgcca tcaggagata gggtgagtcg acatgtctat tactcaccca
    31141 aagcagtcct acaaagcagg aattttctgt tacttttttg gaaatagtaa cgtttataca
    31201 gctttgacac ttcgtatcaa agcgccaaac acactccgag ggatttacag aaagcagaaa
    31261 aggaatgatc tggtataaga tcattccttt tctctctttt tctttaagta attatataca
    31321 atgtacgacg aagtcgtcat tgcaatgctg atccaccacc taaagggaac tttaaacaac
    31381 attgataaga taaagaatat aaacaacgaa aatacgttat acccaattaa ttttattgta
    31441 tatctcatga ttaaaagtta atccttccgt tgttaggaat ggcatcattt ttatcccata
    31501 attgtgctaa ataagtcccc ggtgataata aattcatagc ggattctaaa gcaacatcat
    31561 ttacaaacca actacctaga tatctagaaa ttgctgaacg aatagcactt tttgctgcat
    31621 gttttccttt tactttaatt agatttgcaa ggcctgcagt agttcctcct aatgctaaag
    31681 ctattgtagt atctaataga gcacccattt gattaactgt aataccttgc caagctgctc
    31741 taaatggaga gtatgtaggt gggattgtat aatcgccttg taattgtcgg ttaattactt
    31801 ctttgatcca ttgttgtgag acgtctggat gaaaagattg gatttcgttt gcaagtgtat
    31861 tgatttgttc ttctgttaga gaagtgacag gttgaagttc catatttgtt tcaatttgcg
    31921 atacttgttc agaagcgtat acagctgaaa cacttggaat cgctgataca attaacacaa
    31981 ttgacgtcaa aaaaaccgaa ataaatttca ttaatttgtt catgagcttt tctccttttt
    32041 atttgtatct gcttacattt tattatatac tgttattata ttcaagaaaa atatgctatt
    32101 atgttaaaaa aatatttttc aaaatataaa tggacggatt tattttggat tttatttgtt
    32161 attttgacct gcctctatat tggtaaccat gatttgttta ctctcaatca tcaagaattc
    32221 tcttttcgtg gtagcttttg gggtttggta ctggccttat atcacttatt gttcattgat
    32281 aagtttgtaa tttcgaatcg aaaataaaga ttagaactat gattgactgg ctacttttaa
    32341 tattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt atctattttg
    32401 tacaatatct attctttgag acgggagaaa tcgaaatact tgatttatac ggcctatatc
    32461 atatttgggg taaatgtagt atatggtatt caatggttat taagagaact gatttcaact
    32521 atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg tttgtgtacc
    32581 tgttcttatg cgtttttgta atattgaaga ttttcggtaa gttttatacc tttgggaagt
    32641 ctagtttaga atgctttccc aaccagaatc tctgcttcga tggtaatctc tgtcagttgg
    32701 ctccagtcaa tcttgctctg gtcaacatga aagaggagag gagtcatact gagtagggct
    32761 tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga taggatggta
    32821 aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt tgtcagctgg
    32881 tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac ctttatcaag
    32941 ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga gaagatatca
    33001 agcagaatat ccatgttagc gtcttttata ggaagtcgtg ccaagtcgcc aacgaaccaa
    33061 ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt ggagatgtca
    33121 aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata gaatccttca
    33181 ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa gtcagataca
    33241 gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt ttgaaaattt
    33301 tccttgtcat agttagcaga ttgcttgatt tgaggtgcta gattgacata gccaaatttc
    33361 gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag agtcagattt
    33421 tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag tttgggcttg
    33481 agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac tttaggaata
    33541 agtagatggg agattcagta gaaataaaac taattctcca atttatagaa tgaaattgct
    33601 tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt aaaagaagta
    33661 ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt cgcatttggt
    33721 acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc taaagctttg
    33781 gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgttgt gaagcaacat
    33841 ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa agaagagcaa
    33901 ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag gataccaaca
    33961 tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc ttcgttcctt
    34021 ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac agcactttac
    34081 tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt taaaaagaat
    34141 tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag agagtgctta
    34201 ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg tgccgtatcc
    34261 tattcgctat atatggactt gttatcaggc tttgggttat attagagaag cctatcaaac
    34321 actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt tattgtcttt
    34381 gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt tggggaatca
    34441 tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc ttcttgcaaa
    34501 agagagcgat gtattcctag tacagggcga tacggttgtt agtatcaaga gttccgatgt
    34561 tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg atggacaagt
    34621 agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt ttccagttga
    34681 aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag agttacgcat
    34741 tcgtgtaaca gataatcaga tgaacagccg tattttacag ctgattaagt tgatgaagaa
    34801 atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg ataaagtcgt
    34861 taaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt tttctaaggc
    34921 tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc ctgtagctta
    34981 tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg attaaggatg gagatgttct
    35041 ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa tcacaactag
    35101 ttatcctata gttgaaaagg tgttaccttt tggagactat agtgaggaag atattctcag
    35161 aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca tcgtcaagca
    35221 agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat atatcgcaag
    35281 caaggggatc aaatctcata tagatggcca accagttctt attgggaatt atgtcttgat
    35341 gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag agtacaagag
    35401 tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt tctgcattca
    35461 tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac aggggaaaaa
    35521 attgattctg gcaacaggag acaccttgat taggacagag gaattagtca aagatttgcc
    35581 ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag tagagaaact
    35641 gcagaaagca ggtcacacta ttttgatggt tggagatgga ttgaatgact cagcggcttt
    35701 aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta agcagatgag
    35761 tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt cgttatcatc
    35821 atctttgcaa acactcatca agaaaaatat tcaagatacc gttgtcgtaa atagtagttt
    35881 gattggcttt ggcttattta attggctcag tccttcaaat ctctctatct tacataatct
    35941 aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa aatagataga tgagagttat
    36001 taacagcaaa aaggagttac ctttctcgag gttaactcct ttgtttatag ataaatgttg
    36061 aatggtttag taagtcaata caaagtattt tttcttccca cgacggataa cagtcagttc
    36121 attttctaac ttatcagcgt cactcaagac atagtcaagg tcttggatgc ggtcgccgtt
    36181 tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt taactatacc
    36241 agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt ggtagtttgg
    36301 cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt ttcctgcaaa
    36361 gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa caagtgtaac
    36421 aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt caaattgttt
    36481 acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga agcgaacagc
    36541 gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag tcttttcggg
    36601 attgagccag acggcatttc cttctgattt accaaatttt ttaccagttg catctgtgat
    36661 tagtggaaca gtgataacgt gaccagtctt gtccgcctta cgacgaagca attcggtacc
    36721 agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat tatggtcttg
    36781 gttaaggacg aagaagtcgt acccttgcat gatttggtaa gcgaactcag tgtaagaaat
    36841 tcctgtttcg atccgttttt taacagattc cttactcatc atgtagttga ccgtgaagta
    36901 ttttccaatg tcacggagga agtcaatgaa gctgatgctg ccaaaccagt cgtagttgtt
    36961 gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa gttgtccttg
    37021 gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt cagcatcttt
    37081 gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag gtttgtgacc
    37141 tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt gaaggctgtc
    37201 agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg ctttacgcaa
    37261 agcttcttca tcagtcgttt gaaatatcaa accacgctct tttagctcat caaaaatgtg
    37321 catgtgtctt ttctcctttt taaaattatt gtttctacct attgtatcac aaacttgggc
    37381 aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc cttttgtggt
    37441 ataatagata gagtgaggaa atccatgcaa aatcaattaa atgaattaaa acgaaaaatg
    37501 ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg caagaaaggt
    37561 tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc tattttactg
    37621 agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg aatgttggga
    37681 gttgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt gcctcagaca
    37741 gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac ctattcggac
    37801 gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc atctgagcaa
    37861 atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt taaagaacat
    37921 aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt aggtttgggt
    37981 tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt tgttggggat
    38041 gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt ggaacgcgcc
    38101 atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg ccgaaataat
    38161 aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg tgtagatgcc
    38221 agtcagttga ctgttcctca agcagcattt ttagcaggac tcccacagag tcccattact
    38281 tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga aattggctta
    38341 agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag caaagacgag
    38401 tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg cacggttaca
    38461 ggaatttcac gagactattt atactttaca actttggcag aagctcaaga acgtatgtat
    38521 gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga ggcaactcag
    38581 aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa gattactact
    38641 accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta tggctatctt
    38701 ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa ccaaacaggt
    38761 gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa tcatgccttt
    38821 gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg tattgctatt
    38881 gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa ctttgctaat
    38941 ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt gggagaagct
    39001 ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg tgaaaagggt
    39061 gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta cggtattgag
    39121 agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa tggctatcag
    39181 accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat tgaagcagca
    39241 gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc aaaagctact
    39301 gcgacgatta tgcagggatt gctacgagaa gttctatcct ctcgtgtgac aacaaccttc
    39361 aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat tgggaagact
    39421 ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag attaacccta
    39481 ggtggctgga ttgggcatga tgataatcat tcattgtcac gtagagcagg ttattctaat
    39541 aactctaatt acatggctca tctggtaaat gcgattcagc aagcttcccc aagcatttgg
    39601 gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt gaaatcaaca
    39661 ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag tagaggtcac aggttcgact
    39721 gttaccagct attgggctaa taagtcagga gcgccagcga caagttatcg ctttgctatt
    39781 ggcggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag tctaccaact
    39841 ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc aagtactaca
    39901 cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca atcaatggat
    39961 tgccactttt ttcctttcgt gttacaataa gggtatgaat cagtatcaga aaaagattgt
    40021 taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg gaattttagg
    40081 agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta tgcgtttgac
    40141 actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc aagtgctaga
    40201 tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt tggggatttt
    40261 ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga cagcaactat
    40321 tttacagttt attagccctg tttttatcct cttttacaat cgcttggttt atcaaaaacg
    40381 agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt gcttgatggc
    40441 gacaaaggga gatctctctc agttatccat gacgccgcta gctcttataa caggtttgct
    40501 gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta agcgttatgg
    40561 ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca atgtcctctc
    40621 gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt gcctcattat
    40681 cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt ccttggtttc
    40741 tcctttggtg gttgccgtta tcagtgccag tgaacctctc tcttctgctc tcttgagtgt
    40801 tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct tgattatttt
    40861 acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag tcttttctta
    40921 attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag ttgtgaagag
    40981 tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt atctcacatc
    41041 cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc ttttttggta
    41101 gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa atgaacgctc
    41161 aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa gtaacctttg
    41221 aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat gtcctattcg
    41281 gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa gattatgttg
    41341 tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct atcaacgctc
    41401 gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat gctgttatca
    41461 tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg attgacatgg
    41521 gtgccatcct tggtggccgt gctatcgttg gaaaaaatag ccacgttggt gcaggtgcag
    41581 ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga gacaatgttc
    41641 ttatcggtgc taatgcagtg gttatcgaag gagtccaaat cggtagtggt tcagttgtcg
    41701 ctgcaggagc tatcgttacc caagatgtcc cagaaaacgt ggtagtagca ggtgttccag
    41761 ctcgtatcat caaagaaatt gatgcccaaa cccaacaaaa aacagcgcta gaggatgcgc
    41821 ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca gcctctttct
    41881 gctataacgg aggacagata gatgttagat ttgattcaga ctagacgagc tttacaccag
    41941 attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga tgtgattgag
    42001 aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg gattttggtc
    42061 tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat tgatggtctg
    42121 cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg catgcatgcc
    42181 tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc ccttgaggag
    42241 caacccaaga ataatctgct ctttctattt cagcctgctg aagaaaatga agctggtggc
    42301 atgctcatgt atgaggacgg tgcttttgga gattggttgc caaaccaatt ctatggtctc
    42361 catgttcgtc cagatttgaa agtcggccag attgcgacta atactcatac actctttgca
    42421 ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc ttttcctcat
    42481 gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca gtcagttgtt
    42541 agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt tcaagctgga
    42601 accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg tgccttgaca
    42661 caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg ggttgcagct
    42721 gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc tgttgagaac
    42781 aatccagcct tggcgcgtga actgatggac ttctttgacg aaaaagacgg aatcgagttg
    42841 attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc aaaggttgat
    42901 ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc tcaaatgagt
    42961 cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct gaaaaagaag
    43021 gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc ttgcatgaaa
    43081 tgaaggctat atctcaagag caaaaacagg ctatagacca agctttaacc gagcggcttt
    43141 tacaccatcc cttctaccaa gaagccaagg tcatcgcaac ctacctctct ttttctcatg
    43201 agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag gttttaatac
    43261 ccaaaactta tcccaagggg cgcatggagt ttgtggtcta tgatccgcaa cagttggtaa
    43321 aaacttcctt tgccttactg gagccacagg gagatgtgga agtggtggat gcatctcaga
    43381 ttgatttgat tcatgttcct ggtctggctt ttacgacgaa aggatatcgg ataggatacg
    43441 gtggaggcta ttatgaccgc tatctggaac atttttctgg tcgtactttg agtacgatat
    43501 atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt caggaggtat
    43561 taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt cctcttagtg
    43621 acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga cagggcagat
    43681 acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc cgagcaggtt
    43741 tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat tgttaatatg
    43801 ctttcacttt attatcttgg aaggcaggta gaggagattt tcggttctaa gcagtttttc
    43861 tttctctatc ttttatcagg aatgatgggc aatctctttg tttttgtatt tagtcctaaa
    43921 tccttagcag caggcgcttc tacctctctt tatgggctat ttgccgcgat tattgttctt
    43981 cgctatgcaa ctcgcaatcc ttatattcaa cagctagggc aatcctatct gacacttttt
    44041 gtggttaaca ttattggaag tgttctgatt ccaggaatca gcctagcagg ccatatcggt
    44101 ggtgcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga aaaacggatg
    44161 tataatacca gccagagatt aggagcggta gtcttgttcg taggactcgc cattttgctt
    44221 ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat gaaaaaagat
    44281 aaggcatttt ttgaacctta tctttttatt ttattttatt ccttctcagt caattctttt
    44341 ccaagttgga tgaggtaatt cttcaaatca tctttgactt gtgggtgttt gagggcgtag
    44401 tcgatggatg ttttcatgaa gccaaacttg tctccgacat cgtaacgagc cccattgaac
    44461 tcacgagcaa atacacgttg tgttttattg agggtgtcga ttgcatctgt cagctgaatt
    44521 tcatttcctg cacctggagc ttggttttcg aggatttgga aaatttcagg cgtgaggagg
    44581 tagcgtccga taatagcaag gtcgctagga gcgtcctctg gagctggttt ttcaacaaag
    44641 gtttcaacac tgtaaagacc atcttttcct tcgccttgcg gagcaataac cccgtaagca
    44701 gatacttcgt catgagggac tggcatgaca gcgatagtag acgcgtgggt acgctcgtag
    44761 tcatccatga gttgtttggt aagtggaaca gccttttcgt ctgtgatatc catcaagtca
    44821 tcaccaagca taacgacaaa aggttcattt ccgacgaaag ccttagcttg caaaacagca
    44881 tctccgagac cgcgtggatg agtttggcgg ataaaatgca gacgcatgtc agttgtttta
    44941 tcaactagct tcaaaagatc tgttttccct ttttctttga ggttatattc caattcgaag
    45001 tttgaatcaa agtggtcctc aatagaacgt tttgatttac cagtgacaac tagaatatct
    45061 tcaatacctg atttgagagc ttcttccacg ataaactgga tagttggttt gtctacgatt
    45121 ggcaacattt ctttggcaag ggccttggtt gctggtaaaa atcgagttcc tagtccagca
    45181 gcagggatga ctgcctttct aacttttgat gtcataaaaa tcctttctat agagggttaa
    45241 gaccactcat tttctgcttt aaattcattg ttcatgatgt cataaatggc atctttgata
    45301 ttggttccgt gataaataac ttggtaaata gcctgtgtaa tgggcatata gactccaagt
    45361 tcttgggcta gttcataggc tgctcgagtc gttgaaattc cttcgattac catgcccata
    45421 ttagcttcta tatcagctag ggattctcct cgtccgagag catctccagc tctccagtta
    45481 cgagagtgga tggaagttcc cgttacgatc aaatctccca caccagataa gccgctatag
    45541 gtcaatggac tggccccgag tgctacccct aggcgggtga tttctgctaa acctcgagcg
    45601 atgatggctg ccttagcatt atcaccaaat ccaagaccat gtaaagctcc agcaccgaca
    45661 gcaataatat ttttaagagc accagcagtt tcaaccccga taacatccgt attggtataa
    45721 agtcggaagt agtgattact aaatagcttc tgaacgtatt gagctgtttg taaatcttta
    45781 gaagcagcag ttattaaagt taggtcacgc acaatggtct cttctgcatg actaggccct
    45841 gaaacaacga cgatatcact acggagatgt tcaggaattt cttcttcaag aatggttgat
    45901 aatcgtttat ggctatcagg ttctaatccc tttgatgcgt gcatgatgat aaccttatgg
    45961 tccaaggttt gtgcaacttg ctgggcaaca agtcgtgtca cttttgttgg gacaacaaac
    46021 aaaatcgcat ccacatcttt caatgtttct gctaagtcgg tgtaggcaat gatattttcg
    46081 tctagaacga catctttaaa gtagtgctta ttagtatggt gtgtattaat ttcattgatt
    46141 tgctcgggaa gatttcccca aatacgtacc tcgtgtccat tgtcatttaa gacttgtgaa
    46201 agggcggttc cccaagaacc aggccccaag acggcgacgg tttgtttttc catgatttcc
    46261 tccttgatag agttctttct cttattctat catattctag gggattttgc acttgcatta
    46321 ctggggtatg gtggaaaaat acacaaaaac cgagacgaag ggataaactc ttagtcttta
    46381 gttaaagtga gaagaaatct gatagatagt ttgattcagt atatgcttat aatagaggta
    46441 aacaactcag gaagttcttg taggttgcga gagtttggct aaaaaaatca gtcgttcaga
    46501 attttgtggt gatgagtctg aattaagtat ccgtcaatta attagaattg aaaatggaga
    46561 atccagacca acactaacaa agttaaaata tatcgctgaa cgtttggggg ttgaagatta
    46621 caagttgatg ccaagttata tagagttgga taaggaatac ctagaattga agtatttctt
    46681 gatgaggact cctacatacg aagatgaaac tatcgcccaa aagaaagaga gtgttttgat
    46741 aagatttttg aagagtatta tgataggcta cctgaggaag aaagatttat catcccaaat
    46801 tattcatatc tggcactaac gaactacaca gttcaaaaat taccagaaaa gctagttgaa
    46861 atactgtcct tctggtgatt ttgcttaatt tctgatgttc gagacataat tgaggagatt
    46921 tgtcttgatt ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc tcgattttta
    46981 aaataaggtg acttattctg ttaggcatgt tttcccctgc cctctagctc tatatggaac
    47041 agggagtatc agatttatct ggcagattgt atcaaataag gcttgaaact gttttgaata
    47101 ggcatataga cttgagaatt tgagaatatg tcgtctagca gtagagacat attttccggc
    47161 aatatgaagg aagagacgtc gaaaacgctt gatagtcaag gcctttactt catcaccagc
    47221 tagctgcttt aaaaagaggt agagattata agccagacag cccatcatca tacgtacttc
    47281 attcttaatc atggtcgaac tatctgtctt atccccaaag aatcctgctt tcctttcttt
    47341 gataaagttt tcagcattcc ctcgttcacg atagaattga aacagctcct cactatctac
    47401 actgcttaaa ttgttcaaat gaactttttt acaaccataa aaaagagcac ttaatcgtac
    47461 tcttctcttt taaggattag ttgaattaat tcaaatccac cagttctcct gtttctaggt
    47521 agactaggcg ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga tgccctatga
    47581 tataaaggta ttgagttcca ttgggaattg aggtttcttg gtctttcata agtccaatga
    47641 tttcctttga taaggcataa taatattggt caatctgttc atctttttga gcaatactaa
    47701 tagcttttga ggcttggtgc aaaggaaagg caaccaataa atcggctagc atgctgaggg
    47761 ataatttacc catttggtgt aactgttctt cgtcaggggc tagttgattt tcttttagtt
    47821 gcaaaacagc tttagcaatg cctgccatat ggtctcccat acgttcaagg tctgaacaag
    47881 aagacatgat gctaatcaca aatcgaaggt cagacacttg tggctgctgc aaggccaaca
    47941 aacgggcaca ggtcaattcg atagcgcttt gaccttggtt gatagcatga tccttattga
    48001 taattagctc tgccatctcc ttgtctttgg aggctaaggc cagtaaggct tttgaagctg
    48061 tttcaaggac aagttgccct agtcctaaaa aggattgttc taattcatgc aattctaagt
    48121 caaattgatt tctcataggt ttttccttcc ttatccgaac cgtcctgaaa tatagtcttc
    48181 tgtgcgctga tcttttggat tggtaaacac gtcaacggta tctccaaatt cgcaaatttc
    48241 tcctgttaag aaaaaagcag ttttatctga aatacgtgaa gcttgttgca tgttatgggt
    48301 aacaatgata atcgtataat ccttttttag ttgctgaatg aggtcttcaa tttttaaagt
    48361 ggagataggg tctaaggctg aagtcggctc atccattaac agaatatcag gttctactgc
    48421 taaagctcgc gcaatgcaaa ggcgttgctg ctgaccgcca gataaggaca tggcactctt
    48481 tttaagatca tctttgactt cttcccaaat ggctgcccct tttaaagatt tctccactaa
    48541 ggcatctaat tgttttttgt ctcgaatacc atgtgtcctt gggccataag ccacgttatc
    48601 atagatagac atggcaaagg gattaggctg ttgaaaaacc atccctacac gcttacgtag
    48661 ctgattaagg ttgaatttgc tactataaat atcttgctca tctaagagga cttggccttc
    48721 aatatggcaa gaaggaacca aatcgttcat ccggttaagg gtttttagaa aagttgattt
    48781 gccacaacca gatgggccta tcaaggcagt aatctgtctt tctggtaatt gaatcgaaat
    48841 attttttaag gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg aaaatgttcc
    48901 catactagga agctcctttc acaagttttc gagataataa gcttgataga gtatttatca
    48961 ttaaaacagt aataatcaaa atcacaccgg tagcataggc ttcattgaca tgtagcccct
    49021 cacttgacag catatacata tgcagggcta gagaacgacc tgaagacatg agactacttg
    49081 gcgtattggt agaggtacct aatgtataca tgagggcagc tgtttcacca acgatacggc
    49141 caatagctag tatcactcca gctaaaatac ctggcatggc aactggtaga acaattctaa
    49201 aaacagtccg taacttacct gccccaagtc cataacttgc ttgacgcatg ctatcactaa
    49261 cagataaaag ggcttcttct gttgagcgaa taatgactgg caacaccatg ataactgagg
    49321 ttaagattcc tgataacaga gagtattgaa aacctaagaa gactacaaag aagagcatgc
    49381 caaacagacc aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc aatcgcatga
    49441 ttttaacaca aagggaatct ttttttgtat attccacaag ataaaaacca gcaaaaatcc
    49501 ctatgggcaa ggctaaaaga agagcaccaa agaccagaat aacggtggaa ataatcgctg
    49561 gcataaggga aatgttctca gaagtataag tccaagaaaa gagggataga cttagatgag
    49621 gtaagccttt gatgaggata aaaccaatga ttaaaaagag agagccaaag gttaaagctg
    49681 aaaaacaata aacgagaagt tttagcaggt atttactcat aagatgattt tcctttcaag
    49741 taggcaaagt aggcattaat caagagaata aggaaaaaga gaactgctga ggttgcaata
    49801 agggcttccc tatgctgacc tgatgcgtaa gccatctcca gaacaatatt ggttgttaag
    49861 gttctggttc ctgaaaagag tccacttgga ataattggct ggttgcctgc caccaaaata
    49921 actgccatgg tttcacctac tgcgcgaccg attcctaaaa taactgctga taaaatacca
    49981 gatctcgcag ctggcaagat gacactaaaa atactccgtt catgactagc tcctagagcc
    50041 aagctaccag aataatacgt tttgggaact gttcggatag cagattctga caaactgata
    50101 atggttggca aaatcattat tcctaatagt aacgaagcgg ttaggacact catgccattt
    50161 cctaaaaagc ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc ataaacaata
    50221 gatggaatgg ctgccatcaa gttgatagct gattttaaga agccatagac gggctttgga
    50281 caataataaa ccataaacac cgatgtcaag atgcctgttg gcaccccaat cacaatcgct
    50341 cctaaggtaa ttaataagga accaacgatc attggtaaaa taccatagct tgccggaatg
    50401 ttcgttggcg accaatcact gcctaataaa aaacgggcaa agccgtagtt agctatgaaa
    50461 ggtaagccat tactaaaaat aaagaaacag attagcaaaa tagctacaac agctactgtt
    50521 gcactcatga aaaaaattgc cctaaaaact gcttctttga aggcttgttt tgtcacatct
    50581 tgtcctttct agtgaagaaa gtaagggaga tacgacacct ccctacttgc cttctttatc
    50641 ttattgtacg atgaaacgtc tgcatctctt tagagattta tggagcaaac attttattta
    50701 atcttgtccc aggtggttaa tttgccacta aaaacgtctg caagttcagc catactgact
    50761 tggcttgcct tattgtcatt attgaccaca acagcaatac cgtctaaagc aatagcatca
    50821 tgggtgagac tcttaccttc ttcaggagtt aattccctag aaaccatacc aatatcagcg
    50881 gttttctcct taacagcggt aatacctgct gaagacccat tagaggtaat atcaatcgta
    50941 acttctggat tttctttttt ataagcttct gctaattttt ccattaaaga agatactgaa
    51001 gtggaaccta caacagacaa cttgcctgat aagtgttggc ttgtatattc tgtggtttcg
    51061 gttttagctt caataaattt attatctgtg accacttgtt gaccttgttt ggagtggata
    51121 aagctgataa aatcttgacc tagcttggaa agattagaag accaaacaat gttgaaggga
    51181 cgttgaagag ggtatttacc atctaaaact gtgtctcgac tagccttgac accatcaatc
    51241 tctaaagctt tgacagattt cgttaaagat cccaaggaga tgtagccgat agcattagca
    51301 ttcccttgaa ctgctgagag aacaccttct gtactatttt gaatcacagc tgttttggca
    51361 gtgttgtcaa tttttttatc accgtctttt ttgagaatcc ctgtgatttc tgtgaaggca
    51421 ccccgtgttc cagagccatt ttctcgtgaa atcacctcaa tcgttcctga agctgactgt
    51481 ttggaagcag ctgactgatt gccacaggca acaagcccaa atcctgataa gccaatggct
    51541 gcaagagtaa gcattttttt gaatttcata ataatcacct ttatctctat gtatttttct
    51601 tgtgtaggct tactacattt atagtctaac aagtctttgt aaaggtttat ccctgattca
    51661 tgtaaagatt gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg ctcctaaaaa
    51721 tagctttaaa aattattagt cctgtgcgaa agattggtta ggaagaaaaa tcgtgaagca
    51781 actgcctctg ccaagctgac tcgtcaccgt gacttggcca cctaataatt gactgagttc
    51841 tttgacaatg gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac ctttattaac
    51901 tcggtaaaaa cgttcaaaaa tacgatcctg ctctaattga ctaataccaa tccctgtatc
    51961 tgatacagaa atcttaatgc cttcgttcac cttttgggtc ttgacctcaa tttttccccc
    52021 ttgttcagtg taacggatgg cattggataa aagattgagt aagatttggg aaagtaattg
    52081 actatctgat acgagggtga catcatctgg cacctgcacc tttagctgta aatccttctt
    52141 cttgagctga ggttgcaagc tttgagtcaa atcctgtaca aattctgcca aagaaagggt
    52201 cgtccattgt ataggcattt gttgagcctt agataaggta agaagatgct caacaatatg
    52261 ctcaagacgc aagctttctt tgtaaataat gtctagaaag tcatccttga gcgcttcttc
    52321 ttcagctgac atccccttaa tggtttcagc aaagccctta atcgaagtaa ctggtgtcct
    52381 caattcatgg gaggcatttg agacaaaggc taaatttaac ttttcataag ttctaatcgt
    52441 tgttaaatca tatagcaaga cgagcacagc ttccacagat tgggtggggc taaaaacggg
    52501 aactgctgtc acttctaaaa tcaagtcacc ctcatgaaac ccacttactt cttgttttaa
    52561 ccttgttttt tgatcaaagg cttggtgaac taaatttcga atatccatcc gtttgaggtc
    52621 atcaagtgaa cttatgtcgc cgtccacatc gggaaaataa tgaggcagag agcgactgga
    52681 taataacatc tgaccttgag cggaaactaa aaacgtcccc atggttaggt gcgacagaag
    52741 aacctccatt gtttcggcta ggtccttgta ttgctgatcc tgttgggaga ctttggtttt
    52801 tagggcagac acatactgag ccaaagactt taagtcttct tgcccttttt ctaaaaagta
    52861 ttcactactg gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc atttccaaag
    52921 gcaaaagagc cagtagccac cttgtcccaa agaaagggct agaagaaaga gaccgatgcc
    52981 tttactgatc caagttaata ccatccctgc aatcagaatg aggctaacac ttagattgac
    53041 tagccaaaat tgaaggtagc gtttcatcta taactccttg aacttataac cataaccccg
    53101 aatggttcga ataaattgag gggctttagg attgtcttca attttttccc tcaacttacc
    53161 aatatgaacg tccaccaaac gtgtttcctg cccaaagtca tacccccaga tacgttccaa
    53221 aagacgctct ctagtcagtg tcatgttggg atgtttcata agatagagca agagttcaaa
    53281 ttcttttggg gtcaaactca gtaacttatt cgccttgtag acttcatgac gctcagggta
    53341 tactttcaag gtcccaaata gccaagaatc gtcagcgata ttatctgaat catctccttc
    53401 ttgttctcct ttagttcgcc tgaggacagc cttgacacgc gccagcaatt ctctagggct
    53461 aaaaggtttg gtcaggtagt catcagcccc taattccaag gccaaaacct tatcaaattc
    53521 atcacttttc gcagaaacca tcataattgg agttttgacg cctttggctc tcagccgctt
    53581 acaaacttcc atgccatcta attgtggtaa catgatatca agcaagataa aatcaaaggg
    53641 ttctgtttct gccaaagcta aggccttccg tccatttgtt accaattgag tagaaaagcc
    53701 ttccttactt aaatggtagt caagcaattt cagaatgtgt tcttcatcat ccactaataa
    53761 gacttgtttt gtcatctatt atctcctatt ggtaacatta taacacaatt atcagaaatc
    53821 ctaacattgc taaatcagat taaatttgct tatcaagact agtatctggt caaacgctca
    53881 atcatctcct tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa taattcaaaa
    53941 tcctcaaatt caaaaccagg agcaacaaga caagaaacca gagcatcatc cttatcaact
    54001 gttgatcccc aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc tttggatatg
    54061 tccaggccta aagtgactgc ttcgtagtga ccatctgctg taatcatgtg aacagtaagt
    54121 ggggattctg catgaaaata ccagatttca tctgctgtca atcggtgaaa atgtgaagga
    54181 ttcgtttctt cttaataaga aataaatact ggtataaagc gcccttccct taccagcaag
    54241 gtttatagtg tctgaagctt tttttgtttg tctaaaatag ccaccttcaa catggggagc
    54301 taactctaga gttcttatca agtcttcttt atccgtcgga gccaatgggt tgaagtaact
    54361 cttgttcaaa gtggtgttac gatttcaaga actcctctca gttctgagga cacggtaatg
    54421 attgatgcga cggaagtaca aatcaatcgc cctaaaaaaa gaattagcga atcattctgg
    54481 taaaaagaaa tttcacgcta tgaaggctca agcgattgtc acaagtcaag ggagaattgt
    54541 ttctttggat atcgctgtga actatagtca tgatatgaag ttgttcaaaa tgagtcgcag
    54601 aaatatcgga caagctggta aaatcttggc tgacagtggt tatcaagggc tcatgaagat
    54661 atatcctcaa gcacaaattc cacgtaaatc cagcaaactc aagccgctaa cagttgaaga
    54721 taaagcctgt aaccatgcgc tatctaagga gagaagcaag gttgagaaca tctttgccaa
    54781 agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat catcgtaaac gcttcggatt
    54841 acgaatgaat ttgattgctg gtattatcaa tcatgaacta ggattctagt tttgcaggaa
    54901 gtctattatt tggttaggtg aattagtgaa gcgtttaggc aagtgtctct ggttacgacg
    54961 tcatggcctc taaatcgatt atatttaggg gtcatgacta gtgaagcagt tagctagttc
    55021 gcatataagc ggctagcgtc taacaattag gaactttagt tccaataact ttaagattac
    55081 gacgttttag gacataaatc gatcatattt atgtcctaaa actagtgaag cgcctagcca
    55141 aagtccgaat aggatttggc gttagttact tagattgctt tgcaatcaag taactttggc
    55201 gatttacatc ttctctggtg cttctactcc aagcaagcga agggcttctt tgagaacgac
    55261 tgcggttgcg tagctgaggg ctagacggct gtcgcgttct gggctttcat ccaagatacg
    55321 tgtatgtgca tagtatttgt taaaggattg agccaggcta attgcaaatt tagcaatgat
    55381 agaaggttca aagttatctg ccgcacggtt gataatacgt gggaagtctt gaatgagttt
    55441 aatgatttcc cagctttcag tatcattcaa gctatagttg ccagctgttt ctggtttgaa
    55501 atcggctttg cgtaagatag attggatacg agcgtaggca tattgaacgt aaggtccagt
    55561 ttcaccctcg aaggatacca tagcttctag gtcgaagtcg tatccatttg tacggtcagt
    55621 tttgaggtca tagaatttaa tggctccaac cccaacagca tgtgctactt ggtctttgtt
    55681 ttctagttca ggatttttag cctcgatttg gaccttggca cggctaacag cctctgcaac
    55741 agtaggctct agcaagatga cattcccttt acgagtagag agcttcttcc cttcttttgt
    55801 aaccagacca aaaggaacgt gggtaatgtc gtcactccaa tcgtagccca tctcttgcaa
    55861 gacagctttg agttgtttaa agtgggcaga ttgctcttga ccaacgacgt agatagattt
    55921 agcaaattgg tattcatttt tacggtagag ggctgcagcc aagtcacgtg tgatatagag
    55981 agttgcacca tcagacttct tgatgagggc tggatgttca attccatatt tctcaagatt
    56041 cacaacttgg gcaccttctg attcaagaag tagtcctttt tcagaaagaa tgtctacaac
    56101 tgcatccatc ttatcattgt agaaggcttc tccgttatag ctgtcaaatt caaccttcaa
    56161 ttcattgtaa aggcggttaa attccactaa actttcatcg cggaaccatt gccaaagagc
    56221 gagagcttcc tcatctccat tttcaagttt acggaaccat tcgcgcgctt cttcatccaa
    56281 gctagggtca ttttcagctt cagcgttgat gcggacatag agtttaagga gttcatcgat
    56341 tggatgagct tttacagctt cttcgtcgcc ccatttttta taggcaacaa tcaacatccc
    56401 aaattgttta ccccagtctc ccaaatggtt gaccttgacc gtttgataac cgattttttg
    56461 gaaaatatgt gacaagctat ctccgataac agttgaacgc aggtggccaa tagaaaatgg
    56521 tttagcgata ttcggactag acatgtcgat aacaacattt tcttgtttac caatattttg
    56581 gtcagcatag tgttcttttt cagtggtaac agcttgcaat acttgagcag aaatggcaga
    56641 tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca actttttcaa aggcttggct
    56701 gttcattttt tcagccagtt cagccgcaat catttgtggt gctttacgtt cgacttttgc
    56761 aagagaaaaa gcagggaaag caatgtctcc catttctgag tttttagggg tttccagtaa
    56821 ctttaaaaca gcctcttggt ccaggctatc aatgatgcta gataattcgc tagcaatcaa
    56881 ttcttttgta ttcattaaga gctccttttt ggacttttct actattttat cacaatttta
    56941 aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg gtataatatg gttataaata
    57001 tagttataaa tatgcacgca agaggatttt atgagaaaaa gagatcgtca tcagttaata
    57061 aaaaaaatga ttactgagga gaaattaagt acacaaaaag aaattcaaga tcggttggag
    57121 gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg atttgcgcga aatcggcttg
    57181 accaaggtca agaaaaatga tatggtgtat tatgtactag taaatgagac agaaaagatt
    57241 gatttggtgg aatttttgtc tcatcattta gaaggtgttg caagagcaga gtttaccttg
    57301 gtgcttcata ccaaattggg agaagcctct gttttggcaa atattgtaga tgtaaacaag
    57361 gatgaatgga ttttaggaac agttgctggt gccaatacct tattggttat ttgtcgagat
    57421 cagcacgttg ccaaactcat ggaagatcgt ttgctagatt tgatgaaaga taagtaaggt
    57481 cttgggagtt gctctcaaga cttatttttg aaaaggagag acagaaaatg gcgatagaaa
    57541 agctatcacc cggcatgcaa cagtatgtgg atattaaaaa gcaatatcca gatgcttttt
    57601 tgctctttcg gatgggtgat ttttatgaat tattttatga ggatgcggtc aatgctgcgc
    57661 agattctgga aatttcctta acgagtcgca acaagaatgc cgacaatccg atccctatgg
    57721 cgggtgttcc ctatcattct gcccaacagt atatcgatgt cttgattgag cagggttata
    57781 aggtggctat cgcagagcag atggaagatc ctaaacaagc agttggggtt gttaaacgag
    57841 aggttgttca ggtcattacg ccagggacag tggtcgatag cagtaagccg gacagtcaga
    57901 ataatttttt ggtttccata gactgcgaag gcaatcaatt tggcctagct tatatggatt
    57961 tggtgacggg tgacttttat gtgacaggtc ttttggattt cacgctggtt tgtggggaaa
    58021 tccgtaacct caaggctcga gaagtggtgt tgggttatga cttgtctgag gaagaagaac
    58081 aaatcctcag ccgccagatg aatctggtac tctcttatga aaaagaaagc tttgaagacc
    58141 ttcatttatt ggatttgcga ttggcaacgg tggagcaaac ggcatctagt aagctgctcc
    58201 agtatgttca tcggactcag atgagggaat tgaaccacct caaacctgtt atccgctacg
    58261 aaattaagga tttcttgcag atggattatg cgaccaaggc tagtctggat ttggttgaga
    58321 atgctcgctc aggtaagaaa caaggcagtc ttttctggct tttggatgaa accaaaacgg
    58381 ctatggggat gcgtctcttg cgttcttgga ttcatcgccc cttgattgat aaggaacgaa
    58441 tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca tttctttgag cgtagtgact
    58501 tgacagacag tctcaagggt gtttatgaca ttgagcgctt ggctagtcgt gtttcttttg
    58561 gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac cttgtctagt gtgccacgga
    58621 ttcgtgcgat tttagaaggg atggagcaac ctactctagc ctatctcatc gcacaactgg
    58681 atgcaatccc tgagttggag agtttgatta gcgcagcgat tgctcctgaa gctcctcatg
    58741 tgattacaga tgggggaatt atccggactg gatttgatga gactttagac aagtatcgtt
    58801 gcgttctcag agaagggact agctggattg ctgagattga ggctaaggag cgagaaaact
    58861 ctggtatcag cacgctcaag attgactaca ataaaaagga tggctactat tttcatgtga
    58921 ccaattcgca actaggaaat gtgccagccc actttttccg caaggcgacg ctgaaaaact
    58981 cagaacgctt tggaaccgaa gaattagccc gtatcgaggg agatatgctt gaggcgcgtg
    59041 agaagtcagc caacctcgaa tacgaaatat ttatgcgcat tcgtgaagag gtcggcaagt
    59101 acatccagcg tttacaagct ctagcccaag gaattgcgac ggttgatgtc ttacagagtc
    59161 tggcggttgt ggctgaaacc cagcatttga ttcgacctga gtttggtgac gattcacaaa
    59221 ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt tatgggggct cagacctata
    59281 ttccaaatac gattcagatg gcagaagata ccagtattca actggttaca gggccaaaca
    59341 tgagtgggaa gtctacctat atgcgtcagt tagccatgac ggcggttatg gcccagctgg
    59401 gttcctatgt tcctgctgaa agcgcccatt taccgatttt tgatgcgatt tttacccgta
    59461 tcggagcagc agatgacttg gtttcgggtc agtcaacctt tatggtggag atgatggagg
    59521 ccaataatgc catttcgcat gcgaccaaga actctctcat tctctttgat gaattgggac
    59581 gtggaactgc aacttatgac gggatggctc ttgctcagtc catcatcgaa tatatccatg
    59641 agcacatcgg agctaagacc ctctttgcga cccactacca tgagttgact agtctggagt
    59701 ctagtttaca acacttggtc aatgtccacg tggcaacttt ggagcaggat gggcaggtca
    59761 ccttccttca caagattgaa ccgggaccag ctgataaatc ctacggtatc catgttgcca
    59821 agattgctgg cttgccagca gaccttttag caagggcgga taagattttg actcagctag
    59881 agaatcaagg aacagagagt cctcctccca tgagacaaac tagtgctgtc actgaacaga
    59941 tttcactctt tgatagggca gaagagcatc ctatcctagc agaattagct aaactggatg
    60001 tgtataatat gacacctatg caggttatga atgtcttagt agagttaaaa cagaaactat
    60061 aaaaccaaga ctcactagtt aatctagctg tatcaaggag acttctttga caattctcca
    60121 cttttttgct agaataacat cacacaaaca gaatgaaaag gagctgacgc attgtcgctc
    60181 ccttttgtct attttttaag gagaaagtat gctgattcag aaaataaaaa cctacaagtg
    60241 gcaggccttg gcttcgctcc tgatgacagg cttgatggtt gctagttcac ttctgcaacc
    60301 gcgttatctg caggaagtat tagacgccct ccttactggg aaatatgaag ctatttatag
    60361 tatcggggct tggttgattg gtgtggccgt agtcggtcta gttgctggtg gactcaatgt
    60421 tgtcctcgca gcctatattg cccaaggagt ttcatccgac cttcgggagg atgccttccg
    60481 taaaattcaa accttttctt atgctgatat tgaacaattt aatgcgggaa atctagtcgt
    60541 tcgaatgaca aatgatatca accagattca gaacgttgtc atgatgacct tccaaattct
    60601 tttcagactt cccctcttgt tcatcggttc gtttatccta gcggttcaaa ccttaccttc
    60661 tctgtggtgg gtgattgttc tcatggtagt cttgattttt ggtttgactg ctgtcatgat
    60721 gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt cttgagcgca tcaatgccat
    60781 tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc tttgtccaag aaaaagagca
    60841 atttgctaag tttacagagg tctcagacga gctttttggt caaaaccttt acattggtta
    60901 tgccttttca gtagtggaac cctttatgat gttggttggt tacggggcgg tcttcctctc
    60961 tatttggctg gtcgcgggaa tggttcagtc ggatccgtct gttgttggtt ccatcgcttc
    61021 ttttgttaat tacctaagcc agattatctt taccattgtt atggttggat ttttgggaaa
    61081 ttctgtcagc cgtgccatga tttccatgcg tcgtattcga gaaattcttg acgcagagcc
    61141 agctatgacc ttcaaggata tcccagatga agagttggtt ggaagcctta gctttgaaaa
    61201 tgtgaccttt acctatccaa tggacaagga accgatgctg aaagatgtga gctttactat
    61261 tgaacctggt caaatggttg gtgtagttgg agcgactggt gcaggaaagt caaccttggc
    61321 tcaattgatt ccacgtctct ttgatccaca gaacggggcc attaaaatcg gtggcaagga
    61381 tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt tccatcgttc tccaacgtgc
    61441 cattcttttt agtggaacga ttgcagataa cttgagacag gggaagggaa atgctactct
    61501 atttgaaatg gagcgcgcag ccaatattgc ccaggctagt gaattcattc atcgtatgga
    61561 gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat ttctctggtg gacaaaaaca
    61621 aaggatgtcg attgcgcgtg ggattgtcag caatccacgt attctgattt ttgatgattc
    61681 gacctcagcc ttggatgcca aatcagagcg cttggtgcaa gaagctttga ataaggactt
    61741 gaaggggacg acaaccatta ttattgctca aaaaattagc tcggttgtcc atgcagacaa
    61801 gatcttggtt ctaaatcaag gacgattgat tggtcaaggt acgcatgcag acttggttgc
    61861 caacaatgcc gtttaccgtg aaatctatga aacacagaaa tgaaagacaa actataagaa
    61921 aagtcaatag ttttatctaa actatttctt atttcaattt gatgatttgg cgatgatttt
    61981 agagcacggc aaaaggccct tgaaaaagtc cattttttca aaggtaatcc tgtgttaatt
    62041 tcagaaatta catcactttt tgttcgtcaa atggcagctc tttttttagg atataaaaca
    62101 gggttcggat aagttttttt gcaaggtgga tgatggctac attgtaatgt tttccttgtt
    62161 ctaatttagt cttaagatag gccttaaaag caggcgaaaa gcgagggcat gctttggcag
    62221 cttgtatgag tacctaccgc agatgagggg aactccgttt gaccattctt cctgctaaat
    62281 caatctgatc tgactgataa atagaagaat ccagtccagc gaaagcttgt aattgagcag
    62341 gattatcaaa ggcatgaata tttcgaatct cagctaaaat gaccgcccct aaacgatccc
    62401 caatcccagt aaccgtcgtg atgaccgagt tgaactcagc catcaagtca ttgacacatg
    62461 tttccgcctt gtcaatgagc cccttgtaat gtttgatgtt ttcattacac gagataaaac
    62521 gtctatgcgt tatcaaactc attaccaatt aaaacaaaaa gctgtggtta gatcctttcg
    62581 gaaattgtca agcgattgga ggaaatgaac taatccacag cggcttattc caagtatacc
    62641 acttgggctt tggcagtagc taactgcgct aaatataata taaggaggag taaaatgaag
    62701 acagttcaat ttttttggca ttattttaag gtctacaagt tctcatttgt agttgtcatc
    62761 ctgatgattg ttctggcgac ttttgcccaa gccctctttc cagtcttttc tggacaagcg
    62821 gtgacgcagc tagccaattt agttcaagct catcaaaatg gcaatccaga acttgtatgg
    62881 caaagcctat caggaatcat ggtcaatctt ggcctgctgg ttttggttct atttatctct
    62941 agtgtaatat acatgtgtct catgacgcgc gtgattgcag aatcgaccaa cgagatgcgc
    63001 aaaggtctct ttggtaagct tgctcagttg acggtttctt tctttgaccg tcgacaagat
    63061 ggcgatatcc tgtctcattt taccagtgat ttggataata tcctccaagc ctttaacgaa
    63121 agcttgattc aggtcatgag caatattgtt ttatacattg gtctgattct tgtcatgttt
    63181 tcgagaaatg tgacgctggc tctcatcacc attgccagca ccccattggc tttccttatg
    63241 ctgattttca tcgtgaaaat ggcacgcaaa tacaccaacc tccagcagaa agaggtaggg
    63301 aagctcaacg cctatatgga tgagagcatt tcaggccaaa aagccgtgat tgtgcaagga
    63361 attcaagagg atatgatggc aggatttctt gaacaaaatg agcgcgtgcg caaggcaacc
    63421 tttaaaggaa gaatgttctc aggaattctt ttccctatca tgaatgggat gagcctgatt
    63481 aatacagcca tcgtcatctt tgctggttcg gctgtacttt tgaatgataa gtctattgaa
    63541 acaagtacag ccctaggttt gattgttatg tttgcacaat tttcacagca gtactaccag
    63601 cctattatcc aagttgcagc gagttgggga agccttcagt tggcctttac tggagctgaa
    63661 cgaattcagg aaatgtttga tgcagaggag gaaatccgac ctgaaaaggc tccaaccttc
    63721 actaagttgc aagaaagtgt tgaaatcagt catatcgatt tttcatactt gcctgataaa
    63781 cctattttga aagatgtcag catttctgcc cctaaaggcc agatgacagc agttgttggg
    63841 ccgacaggtt caggaaaaac gactattatg aacctcatca atcgctttta tgatgttgat
    63901 gctggtggta tttattttga tggtaaagac attcgtggct atgacttaga tagtcttaga
    63961 agcaaggtgg gaattgtatt gcaagattcg gtcttgttta gcggaacgat tcgagacaat
    64021 atccgatttg gtgtgccaga tgctagtcag gaaatggttg aggtagcagc aaaagcaacc
    64081 cacattcacg actatatcga aagtttgcct gataagtacg atactcttat tgatgatgac
    64141 cagagcatct tttcaacagg gcagaagcaa ttgatttcaa tcgctcgaac cctgatgaca
    64201 gatccagaag ttctcattct cgatgaagca acttcaaacg tagatacggt gacagaaagc
    64261 aagattcagc atgccatgga ggtggttgta gcaggtagaa ctagtttcgt cattgcccac
    64321 cgcttgaaaa ccattctcaa tgcagatcag attattgtcc ttaaagatgg agaagtcatt
    64381 gaacgtggta accaccatga acttttgaag ctaggtggct tttattcaga actctatcac
    64441 aatcaatttg ttttcgaata agaaagaagt tgtcctatgt gggcagcttt ttcttgtcca
    64501 taaaaaatgt ttatcacagc cttaaaaaaa acatattaga cgaaagtcat tttgagtgat
    64561 atgataggac tatcgttagc attcgaaagg agaggcatca tggctagaac ggttgtagga
    64621 gttgctgcaa atctatgtcc cgtagacgca gaaggcaaaa tcattcattc atctgtatct
    64681 tgtagattcg cagagatcat tcgtcaagtc ggtggtctcc ctttagtcat tcctgttggt
    64741 gatgagtcag ttgtacgtga ttatgtggaa atgattgaca aactcatttt gacaggaggc
    64801 caaaatgttc atcctcagtt ttatggagag aagaagaccg tcgagagcga tgattacaat
    64861 ctggtccgtg acgaatttga attggcactc ttgaaggaag cgcttcgtca gaataaacca
    64921 attatggcaa tctgtcgcgg tgtccaactt gtcaatgttg cctttggtgg aaccctcaat
    64981 caagaaatcg aaggtcactg gcaaggacta cctttcggga catctcactc tattgagaca
    65041 gtagaaggaa gcgtggtggc taagctattt gggaaagaaa gtcaggtcaa ctcagtccat
    65101 cgtcaaagca ttaaagattt ggcacctaat ttccgtgtaa ctgctattga ttcaagagac
    65161 caaactattg aagcgattga gtctatcgac gagcaccgca ttatcggttt acagtggcat
    65221 ccagagtttc tggttaatga agaagatggc aatttagaat tatttgagta tttattgaat
    65281 gaactgtaac gattggaaca tctggtcgtt ctttctttta ttttttcaaa atttttagaa
    65341 tgtggcattt tacgcaaacg tttgaattct gataaaaatt ggagaaattc gacaaaaaaa
    65401 cttgaaaaaa acgaaggtaa gcgttatgat agaaaagaag aaatattgga ggaagaacat
    65461 gtcacatatt aaatttgatt attcaaaagt tttagacaaa tttgttgcac cacatgaagt
    65521 ggaatacatg caatcacaag taacagcagc agatgaattg atccgtaaag gaactggtgc
    65581 tggtagcgac ttcttgggat ggttggacct tcctgaaaaa tacgaccgcg aagaatttga
    65641 ccgcatcttg aaagctgctg agcaaatcaa gtcagacagc gatgttttgg ttgtgatcgg
    65701 tattggtgga tcttaccttg gtgcaaaagc agcaatcgac ttcttgaatc accattttgc
    65761 taacttgcaa acaaaagaag aacgcaaagc tccacaaatc ctttacgcag gaaactcaat
    65821 ctcatctact taccttgctg acttggtaga gtatgttgca gacaaagact tctcagtaaa
    65881 cgtaatttct aaatcaggta caacaactga accagcgatt gctttccgtg tctttaaaga
    65941 actcttggtt aagaaatacg gtcaagaaga agctaacaaa cgtatctatg caacaactga
    66001 ccgccaaaag ggtgctgtta aggttgaagc agacgctaac ggttggggaa catttgttgt
    66061 tccagatgat atcggtggac gcttctcagt attgacagcc gttggtttgc ttccaatcgc
    66121 agcatcagga gctgacataa aagctcttat ggaaggtgcg aatgcagctc gcaaagacta
    66181 cacttcagac aaaatctctg aaaacgaagc ttaccaatac gcagtcgttc gtaacatcct
    66241 ttatcgtaaa ggctatgcaa ctgagatctt ggtaaactat gagccatcac ttcaatactt
    66301 ctcagaatgg tggaaacaat tggctggtga atcagaagga aaagaccaaa aaggtatcta
    66361 cccaacttca gccaacttct caactgactt gcactcactt ggtcaattta tccaagaagg
    66421 aactcgtatc atgtttgaaa cagttgtccg tgttgacaaa cctcgtaaaa acgtgcttat
    66481 tcctactttg gaagaagacc ttgacggact tggttacctt caaggaaaag acgttgactt
    66541 tgtaaacaaa aaagcaactg acggtgttct tcttgcccac acagatggtg atgtaccaaa
    66601 catgtatgtg actcttccag agcaagacgc tttcactctt ggttacacta tctacttctt
    66661 cgaattggca attgcccttt caggttactt gaatgctatc aacccatttg accaaccagg
    66721 tgttgaagct tataaacgta acatgtttgc ccttcttgga aaaccaggat ttgaagaatt
    66781 gagcaaagaa cttaacgcac gtctataata gaagaaaaga gtggtttgcc cactcttttt
    66841 actctcttta tccatagaaa ttggactcag ccaagacttg tgatataata tagaaagcaa
    66901 aaaggcagac gcctagataa taggagaaac tatgtcaaaa gatatccgcg tacgttacgc
    66961 accaagtcca acaggactac tacacatcgg aaatgcccgt acagcattgt ttaactactt
    67021 gtatgcgcgc catcatggtg gaacatttct catccgtatc gaagatactg accgtaaacg
    67081 ccatgtcgag gatggtgaac gttcacaact tgaaaacctt cgctggttag gcatggattg
    67141 ggatgaaagt ccagaatcac atgagaatta tcgccagtct gagcgtttgg acttgtatca
    67201 aaaatacatc gaccaactat tagctgaagg aaaagcctac aaatcttacg ttacagaaga
    67261 agagttggca gctgaacgtg aacgtcaaga agtagctggc gaaacaccac gctacatcaa
    67321 tgaatacctt ggtatgagtg aagaagaaaa agcagcttac atcgcagaac gtgaagcagc
    67381 agggatcatc ccaactgttc gtttggctgt caatgagtca ggtatctaca agtggcatga
    67441 tatggtcaaa ggcgatatcg aatttgaagg tggcaatatc ggtggtgact gggttatcca
    67501 aaagaaagac ggttacccaa cttacaactt tgccgttgtt atcgatgacc acgatatgca
    67561 aatctctcat gttatccgtg gagatgacca tattgctaat acaccaaaac agcttatggt
    67621 ctatgaagct cttggttggg aagctccaga gttcggtcac atgaccttga ttatcaactc
    67681 tgagactggt aagaagttat ctaaacgtga tactaataca cttcaattta tcgaagatta
    67741 ccgaaagaaa ggttaccttc cagaagcagt ctttaacttt attgctcttc ttggttggaa
    67801 cccaggtggt gaagatgaga ttttctctcg tgaagaactc attaaacttt ttgatgaaaa
    67861 ccgcctcagc aagtcaccag cagcctttga tcagaaaaaa ctagactgga tgagcaatga
    67921 ttatatcaag aatgcagacc ttgaaaccat ctttgaaatg gcaaaaccat tcttagagga
    67981 agcaggccgt ttgactgaca aggctgaaaa attagttgag ctctataaac cacaaatgaa
    68041 atcagtagat gagattatcc cattgacaga tcttttcttc tcagatttcc cagaattgac
    68101 agaagcagag cgcgaagtca tgacgggtga aacagttcca acagttcttg aagcattcaa
    68161 agcaaaactt gaagcgatga cagatgataa atttgtgaca gaaaatatct tcccacaaat
    68221 taaagcagtt caaaaagaaa caggtattaa agggaaaaat cttttcatgc ctattcgtat
    68281 cgcagtttca ggcgaaatgc atgggccaga attaccagat acaattttct tgcttggacg
    68341 tgaaaaatca attcagcata tcgaaaacat gctaaaagaa atctctaaat aaagaggata
    68401 caataatgga catctgggaa aagatgtacg aagaagcaca gaaactatac aatccacatg
    68461 aagtatcaga ctttgtttat gccaatcatg ttgtagctgc agtagaagca gaagatggac
    68521 aaatatttac aggattctgt atggagggaa cctgtggtgt tttccatctc tgcgcagaac
    68581 gggcgaccct cttcaatatg taccaatttt caggacaaac taaggttaag aaagtattag
    68641 cctttcgaga caaaccacct tatggtggaa gttcagccat gccttgcggt gcttgtagag
    68701 aattcctttt agagcttaat gctgaaaata aagatgcaga attcatgatg gactataata
    68761 taagaaaaac agttaaagtc gcagaactaa tcccttattg gtggggagaa gaacgtgctt
    68821 ctaagtttaa tgagcgatag aagagtcagt ataattctgg ctttttttac tataagttga
    68881 aaaaat
//
LOCUS       DAVKUR010000005        57597 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKUR010000005 DAVKUR010000000
VERSION     DAVKUR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.005"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VW749_000387"
     CDS             complement(<1..137)
                     /locus_tag="VW749_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0174487.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            307..378
                     /locus_tag="VW749_000388"
     tRNA            307..378
                     /locus_tag="VW749_000388"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:340..342,aa:Glu,seq:ttc)
     gene            384..457
                     /locus_tag="VW749_000389"
     tRNA            384..457
                     /locus_tag="VW749_000389"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Asn,seq:gtt)
     gene            complement(498..1040)
                     /locus_tag="VW749_000390"
     CDS             complement(498..1040)
                     /locus_tag="VW749_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0174488.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(1300..2553)
                     /locus_tag="VW749_000391"
     CDS             complement(1300..2553)
                     /locus_tag="VW749_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0174489.1"
                     /translation="MKCFVGLDISSTKLDVCIMLSDTSTPVTASLSNDLSGATEIKNH
                     ILDLNHTYHFERIVIGMEATSLYSFHPAMFFHEDRQLKELHVEIMVEQPNKIKKYRDA
                     FEENKNDTIDAFYIADYFRIERFSPSFLKEEKYMALQHLTRTRLQIIEQLTRTKQHFI
                     ENIYYKCNTLAYQFKKEELSTNLWSSTMMTLMTDEMTLDELANMPLQELDDWLQKLGK
                     GHFKDSEKLAQTIQAAIRGSYRLSKLQQDSVNVILGLLAREIRNLEKMIKEIDKAIED
                     MVETIPEYQCLTSIPGVGKVYAAGIIAEIGQIERFKDHPQVAKFAGLNWREKQSGNSN
                     SQHTSLVNRGNRYLRYYLVEAANSVRRYDDEYKDFYKKKYHEVPKHQHKRAILLTARK
                     FVRLVDVLLRNHQLYTPPRRIMEDN"
     gene            2909..4667
                     /locus_tag="VW749_000392"
                     /pseudo
     CDS             2909..4667
                     /locus_tag="VW749_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(4697..7240)
                     /locus_tag="VW749_000393"
     CDS             complement(4697..7240)
                     /locus_tag="VW749_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0174490.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYTLMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVLFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSTYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVDFDY
                     FSPIPYEKIENTNNLISVTSSSNEDAAIQYQIEVPENSQIYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7302..8924)
                     /locus_tag="VW749_000394"
     CDS             complement(7302..8924)
                     /locus_tag="VW749_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0174491.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            9130..10155
                     /gene="trpS"
                     /locus_tag="VW749_000395"
     CDS             9130..10155
                     /gene="trpS"
                     /locus_tag="VW749_000395"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0174492.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10307..11785
                     /gene="guaB"
                     /locus_tag="VW749_000396"
     CDS             10307..11785
                     /gene="guaB"
                     /locus_tag="VW749_000396"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0174493.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VW749_000397"
     CDS             complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VW749_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0174494.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VW749_000398"
     CDS             complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VW749_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0174495.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            13463..14713
                     /locus_tag="VW749_000399"
     CDS             13463..14713
                     /locus_tag="VW749_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0174496.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14710..15993
                     /locus_tag="VW749_000400"
     CDS             14710..15993
                     /locus_tag="VW749_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0174497.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            16035..16856
                     /locus_tag="VW749_000401"
     CDS             16035..16856
                     /locus_tag="VW749_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0174498.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16867..17412
                     /gene="pgsA"
                     /locus_tag="VW749_000402"
     CDS             16867..17412
                     /gene="pgsA"
                     /locus_tag="VW749_000402"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0174499.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17409..18236
                     /locus_tag="VW749_000403"
     CDS             17409..18236
                     /locus_tag="VW749_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0174500.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            18221..19060
                     /locus_tag="VW749_000404"
     CDS             18221..19060
                     /locus_tag="VW749_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0174501.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            19053..19847
                     /locus_tag="VW749_000405"
     CDS             19053..19847
                     /locus_tag="VW749_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0174502.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19906..20724
                     /gene="mreC"
                     /locus_tag="VW749_000406"
     CDS             19906..20724
                     /gene="mreC"
                     /locus_tag="VW749_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0174503.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20724..21218
                     /gene="mreD"
                     /locus_tag="VW749_000407"
     CDS             20724..21218
                     /gene="mreD"
                     /locus_tag="VW749_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0174504.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21312..22490
                     /locus_tag="VW749_000408"
     CDS             21312..22490
                     /locus_tag="VW749_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0174505.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22714..23493
                     /gene="rpsB"
                     /locus_tag="VW749_000409"
     CDS             22714..23493
                     /gene="rpsB"
                     /locus_tag="VW749_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0174506.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            23559..24599
                     /locus_tag="VW749_000410"
     CDS             23559..24599
                     /locus_tag="VW749_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0174507.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24845..25168
                     /gene="tnpB"
                     /locus_tag="VW749_000411"
     CDS             24845..25168
                     /gene="tnpB"
                     /locus_tag="VW749_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0174508.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(25309..25596)
                     /locus_tag="VW749_000412"
                     /pseudo
     CDS             complement(25309..25596)
                     /locus_tag="VW749_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25587..25985
                     /locus_tag="VW749_000413"
     CDS             25587..25985
                     /locus_tag="VW749_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174509.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VW749_000414"
     CDS             complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VW749_000414"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0174510.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(27387..28022)
                     /locus_tag="VW749_000415"
     CDS             complement(27387..28022)
                     /locus_tag="VW749_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0174511.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            28078..29376
                     /locus_tag="VW749_000416"
     CDS             28078..29376
                     /locus_tag="VW749_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0174512.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            29373..30035
                     /locus_tag="VW749_000417"
     CDS             29373..30035
                     /locus_tag="VW749_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0174513.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            30115..30663
                     /gene="raiA"
                     /locus_tag="VW749_000418"
     CDS             30115..30663
                     /gene="raiA"
                     /locus_tag="VW749_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0174514.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            30799..32772
                     /locus_tag="VW749_000419"
     CDS             30799..32772
                     /locus_tag="VW749_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0174515.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            32769..33221
                     /gene="rplI"
                     /locus_tag="VW749_000420"
     CDS             32769..33221
                     /gene="rplI"
                     /locus_tag="VW749_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0174516.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            33265..34617
                     /gene="dnaB"
                     /locus_tag="VW749_000421"
     CDS             33265..34617
                     /gene="dnaB"
                     /locus_tag="VW749_000421"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0174517.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            34619..34885
                     /locus_tag="VW749_000422"
     CDS             34619..34885
                     /locus_tag="VW749_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174518.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            34974..36320
                     /gene="cbpD"
                     /locus_tag="VW749_000423"
     CDS             34974..36320
                     /gene="cbpD"
                     /locus_tag="VW749_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0174519.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      36403..36505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            36576..36866
                     /locus_tag="VW749_000424"
     CDS             36576..36866
                     /locus_tag="VW749_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0174520.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            36829..37587
                     /locus_tag="VW749_000425"
     CDS             36829..37587
                     /locus_tag="VW749_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174521.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            37626..38633
                     /locus_tag="VW749_000426"
     CDS             37626..38633
                     /locus_tag="VW749_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0174522.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            38633..39358
                     /locus_tag="VW749_000427"
     CDS             38633..39358
                     /locus_tag="VW749_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174523.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPQGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            39481..39939
                     /locus_tag="VW749_000428"
     CDS             39481..39939
                     /locus_tag="VW749_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0174524.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            39941..42373
                     /locus_tag="VW749_000429"
     CDS             39941..42373
                     /locus_tag="VW749_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0174525.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            42694..43347
                     /gene="rr06"
                     /locus_tag="VW749_000430"
     CDS             42694..43347
                     /gene="rr06"
                     /locus_tag="VW749_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0174526.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            43344..44675
                     /gene="hk06"
                     /locus_tag="VW749_000431"
     CDS             43344..44675
                     /gene="hk06"
                     /locus_tag="VW749_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0174527.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            44758..45285
                     /locus_tag="VW749_000432"
     CDS             44758..45285
                     /locus_tag="VW749_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0174528.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            45364..48102
                     /locus_tag="VW749_000433"
     CDS             45364..48102
                     /locus_tag="VW749_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV0174529.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKPRVRRNSPEIKAKGRVKNYEEANIELSKYMTDLY
                     KLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFAD
                     LLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGG
                     QAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDG
                     AKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKA
                     KLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKK
                     EKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQN
                     TPQVPEAPKSPEVPKVSDTPKAPDTPQVPEAPKSPEVPKVPEAPKAPDTPQVPEAPKS
                     PEVPKVPDTPKAPDTPQVPEAPKSPEVPKVPDTPKAPDTPQVPEAPKAPDTPQIPEAP
                     APETPAPAPEAPKTGWKQENGMWYFYNTDGSMATGWLEYNGSWYYLNANGAMATGWLE
                     YNGSWYYLNTNGAMETGWLEYNGSWYYLNTNGAMETGWLEYNGSWYYLNANGSMATGW
                     LKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGSGALAVNTTVGGYRVNANGKWVN"
     gene            complement(48332..49312)
                     /gene="dusB"
                     /locus_tag="VW749_000434"
     CDS             complement(48332..49312)
                     /gene="dusB"
                     /locus_tag="VW749_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0174530.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(49299..50171)
                     /gene="hslO"
                     /locus_tag="VW749_000435"
     CDS             complement(49299..50171)
                     /gene="hslO"
                     /locus_tag="VW749_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0174531.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            50336..51763
                     /locus_tag="VW749_000436"
     CDS             50336..51763
                     /locus_tag="VW749_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0174532.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            51922..53430
                     /gene="glpK"
                     /locus_tag="VW749_000437"
     CDS             51922..53430
                     /gene="glpK"
                     /locus_tag="VW749_000437"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0174533.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            53472..55298
                     /gene="glpO"
                     /locus_tag="VW749_000438"
     CDS             53472..55298
                     /gene="glpO"
                     /locus_tag="VW749_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0174534.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            55368..56072
                     /locus_tag="VW749_000439"
     CDS             55368..56072
                     /locus_tag="VW749_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0174535.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            56369..56572
                     /locus_tag="VW749_000440"
     CDS             56369..56572
                     /locus_tag="VW749_000440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174536.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(56659..57267)
                     /locus_tag="VW749_000441"
     CDS             complement(56659..57267)
                     /locus_tag="VW749_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174537.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT        17919 a         9853 c        12486 g        17339 t
ORIGIN      
        1 tttcctttct gttgataggc tagtaacaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatat tttagagaaa
      241 aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata tctgctacag
      301 atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
      361 cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt
      421 aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct
      481 gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt
      541 tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca
      601 tgagttagat agatgctact atattctaat tcagtggtat ttagattcag ttgcataaat
      661 cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt
      721 tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca
      781 aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat
      841 gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta
      901 tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca
      961 aatggctgtt ccatcagtaa ttgtaccata gcgttttcaa tagttcgctt tgtttttaag
     1021 cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa
     1081 tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta
     1141 gacaatatgt ttaaaaaagt ctagtggtaa aatgtcaagc gaccccccgc tcaaagtttg
     1201 aaaactattt caaaaaaagg gtgcactaaa gaagccctac tgaaaacgat gttttcacac
     1261 tgtttttagt agattttcaa ggagaggtgc agatataact tagttatctt ccataatcct
     1321 ccttggtggc gtatagagtt gatggttgcg tagtagcaca tccaccagac gcacaaattt
     1381 tctagcggtt agtaagatgg ctcgtttgtg ttggtgttta ggtacttcat ggtatttctt
     1441 cttatagaaa tccttgtatt cgtcatcata acgccttacc gagttggcgg cttcaaccag
     1501 gtagtagcgc agataacgat tgcccctatt cacaagcgaa gtatgttgtg agtttgagtt
     1561 accagattgc ttttctctcc aattcagacc agcaaatttt gcgacctggg gatggtcttt
     1621 aaagcgttcg atttgtccaa tttcggcaat gataccagca gcgtagacct tcccgacccc
     1681 aggtatggag gtcaggcatt gatattcagg aatggtttcc accatatctt caatggcctt
     1741 atcaatttcc ttgatcattt tttccaggtt tcgaatttcc cgagccagaa gtccgagaat
     1801 gacattgact gaatcttgtt ggagtttaga gaggcgataa gaacctctga tagcggcttg
     1861 aatggtttga gcaagcttct cagagtcctt aaaatgccct ttacccagtt tttggagcca
     1921 atcatctaat tcttgaagag gcatgttagc aagttcgtct aaggtcatct catctgtcat
     1981 caaggtcatc atcgttgaac tccataggtt agtagagagt tcttctttct tgaattgata
     2041 agccaaggta ttgcacttgt agtagatatt ttcaatgaag tgctgtttgg ttctggttaa
     2101 ttgctcgatg atttggagtc tggttcttgt gagatgttgg agagccatgt atttctcttc
     2161 ttttaaaaaa gaaggtgaaa atcgctcaat acggaaataa tccgcaatgt agaaagcatc
     2221 aatggtatcg tttttgtttt cttcgaaagc atcccgatac ttcttgattt tattaggttg
     2281 ttcgaccata atctcaacat gtagttcttt caactgccta tcttcatgga agaacatagc
     2341 agggtggaaa ctgtagagac tggttgcttc catgccaatg acaatccttt cgaagtgata
     2401 ggtatgattc aaatcaagga tatgattctt aatctctgtt gccccagaaa ggtcattaga
     2461 gagggaagca gtgacggggg tgctagtatc actcaacatg atacacacat ctaattttgt
     2521 agagctgatg tctaaaccga caaaacattt cattaaggaa ggtctccttt ccattagatt
     2581 tggaagtttt tttgactact gtaaggtttc ccagaaacac cttgttccaa catcctcgca
     2641 taagagaatc cttatcacag cctgacagag ccgcctgcat cctactagat acagaagtca
     2701 agctgtggaa acagctagtg tgttggaagt ttgaacaagg cttgggtaac agacttttta
     2761 atgaagtcca agcaacaagg agaaaaagaa acaaccatga gtccattcca tgactctatt
     2821 gttctagaaa accttgcaat agtcaagtga taacgaataa aacttgggat tgaaatatcc
     2881 ccatgattat atattacgag gagaaactat gtttaaagaa tggaaagcaa tttaaaaaaa
     2941 acaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta caatatcata
     3001 tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt ggcagttgta
     3061 aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa agacatggtg
     3121 tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga ggaaggaaag
     3181 aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga tttatctgaa
     3241 aaagcaacta cattatccaa tattcaatcg acagcagctt atcaatcatt gacaagtgag
     3301 caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat tcaatcggct
     3361 cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt acaaaatcaa
     3421 tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat tacttctact
     3481 tctttgatag gattgtcaag tggattaaca gagatacaag gagctgttac tagcaaatta
     3541 gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg tgttgataaa
     3601 gtttctcagg gcgcaagtca actaagtgaa aaaaatgcta ccttgacagg tagtttggat
     3661 caattagttt caggctcaaa caccttgaca caaaaatctt ctagcttgac agcaggagtt
     3721 ggtcaattag ttgaaaaaac tccagaatta gtatctggta ttgaaaaatt atcaactggc
     3781 tccaattaat tgaatcaaaa gagtcaagaa ttgatagcag gagttgataa attgcagtca
     3841 ggctctagcc aactagctga caaatccagt cagttacttt caggtgtttc tcaattagaa
     3901 agtggagcta ataaattggc agatggagct gggaaactag cagaaggtgg aacaaagtta
     3961 acttctggat tggaaggttt acagacagga cttgcttctt taggacaagg actaggtaat
     4021 gctagtgatc aactcaaatc agcatcaaca gaatctaaaa atgcagagat tttgtcaaat
     4081 ccactcaatc tttccaaaac agacaatgac caagttcctg taaatggaat tgcaatggct
     4141 ccttatatga tatcagttgc tctttttgtt gcagcaatat caacgaatat gatctttgcg
     4201 aagttacctt caggacgtca tccagagagc cgttgggctt ggttgaaatc tcgagctgaa
     4261 ataaatggta ttatagctgt tttggcaggg attttggtat atggaggagt tcatcttatt
     4321 ggtctaactg ctaatcatga aatgagaaca tttattctca tcatcttaac aagtttagta
     4381 ttcatgtcta tggtgaccgc tttaacaaca tggaatagcc gtataggagc tttcttctcg
     4441 cttatttttc ttttattaca gttagcatca agtgcaggta cctatccgct tgctttgaca
     4501 aatgatttct ttagagctat taatccttgg ttgccaatga gttattcagt ttcgggatta
     4561 cgacaaacaa tctccatcaa caagtcattt tcctagctgt catactagct ctatttactg
     4621 gtttaggtat gctagcctat caacctaaga aaatggaaga agattaaaaa aatcgaccga
     4681 ttaactggtc gattttttat gccttagatg actttcgtct gtgattatag attccaaata
     4741 gtaagagaga agtaaaggaa cagattgctc cagtaataaa accattggga atgaaggaaa
     4801 gtgtaatagt tcctttcccc ttgggaatgt caactttcat aaatccagtt tgagcttgtt
     4861 taatttctat tttcttacca tcttggtagg cagaccaacc tttgtcataa ggaatggtga
     4921 agaaaataga tgtatcttgt tggacatcat atgtagcaaa aaccttgttt ttagaagttg
     4981 atactgtgac aggttgttct ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta
     5041 aacgatagaa ggtaggagat tcaaatgata cttgtgaatt tccagggaaa ctaacattga
     5101 tattgaaagt ttttttctct ttagtatatc ctagattaaa gaaggagaag acattatcag
     5161 ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac cttcttttgt ttatcgttag
     5221 aaaagtgaag gtttatgaaa gagagataaa tttggctgtt ttctggaact tcaatttgat
     5281 actggattgc tgcatcctca tttgaagaac ttgtgacact aatcaaatta ttagtatttt
     5341 ctattttttc ataagggatt ggagaaaaat aatcaaaatc aacgttagca agttgattta
     5401 aaaacgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
     5461 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
     5521 gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac
     5581 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
     5641 aggatttaaa cccaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
     5701 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
     5761 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
     5821 ctcgactata agtacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag
     5881 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
     5941 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
     6001 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
     6061 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
     6121 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
     6181 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
     6241 ctatgtaaaa gcttgcaatt agaaatgcaa agaataatac atatatgagt ttcacgtgaa
     6301 acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaaaggaagt agtccaacaa
     6361 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
     6421 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
     6481 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta
     6541 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
     6601 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
     6661 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
     6721 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
     6781 ctaattgact gacagtgaaa ctcatcagag tataggaagt agataaggct agttttaaag
     6841 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
     6901 caaattttaa gagagtggtc agataaacag catctggcat attcgttaga tcaaaaaagt
     6961 aaaccagagg tgagagaaaa ctacccaagt aataactaga cagagcatag aagtttagcc
     7021 ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg
     7081 ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
     7141 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgagag
     7201 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
     7261 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
     7321 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
     7381 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg
     7441 tggtcatggc tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
     7501 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
     7561 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
     7621 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta
     7681 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
     7741 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
     7801 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
     7861 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
     7921 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
     7981 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
     8041 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
     8101 ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca
     8161 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
     8221 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
     8281 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct
     8341 tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
     8401 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
     8461 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
     8521 gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca
     8581 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
     8641 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
     8701 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
     8761 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
     8821 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
     8881 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
     8941 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt
     9001 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
     9061 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
     9121 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
     9181 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
     9241 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
     9301 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
     9361 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
     9421 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
     9481 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
     9541 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
     9601 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
     9661 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
     9721 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
     9781 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
     9841 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
     9901 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
     9961 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
    10021 cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt
    10081 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
    10141 cattacttta actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata
    10201 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
    10261 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
    10321 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
    10381 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
    10441 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
    10501 tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
    10561 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
    10621 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
    10681 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
    10741 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
    10801 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
    10861 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
    10921 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gaatttggtc gtcttctagt
    10981 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
    11041 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
    11101 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
    11161 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
    11221 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
    11281 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
    11341 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
    11401 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
    11461 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
    11521 ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag gaattgaagg
    11581 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
    11641 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
    11701 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
    11761 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
    11821 tcttttacaa tgttgtcaat ttccatttac agaagcttta ccatcctgaa tagtgaagat
    11881 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
    11941 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
    12001 cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta attcgatttc
    12061 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
    12121 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
    12181 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
    12241 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
    12301 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
    12361 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
    12421 atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
    12481 ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
    12541 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
    12601 catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg
    12661 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
    12721 tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg
    12781 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
    12841 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
    12901 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    12961 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    13021 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    13081 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    13141 tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa
    13201 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    13261 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    13321 tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat gtaagcgatt
    13381 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    13441 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    13501 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    13561 tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc
    13621 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    13681 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    13741 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    13801 tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa
    13861 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    13921 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    13981 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    14041 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    14101 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    14161 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    14221 aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga ttgtaatgaa
    14281 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    14341 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    14401 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    14461 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    14521 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    14581 cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg aacaaattga
    14641 caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt actttatgga
    14701 aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt aaaagaaaag
    14761 gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    14821 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    14881 gttgacggat atgtaaaaca atatcctgga ggaattgctc attttcttga acataaatta
    14941 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    15001 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta
    15061 gaaaatttag atttacttga tgaattggta acatcagcac actttactga agcttccatt
    15121 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    15181 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    15241 gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca
    15301 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    15361 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    15421 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    15481 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    15541 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    15601 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    15661 agtcgctttc attttgtcat gttgacaata gatacgaaag agccagttgc tttgtctcat
    15721 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    15781 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    15841 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    15901 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    15961 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    16021 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    16081 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    16141 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    16201 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    16261 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    16321 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    16381 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    16441 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    16501 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    16561 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    16621 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    16681 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    16741 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    16801 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    16861 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    16921 cctattttta tctttatttt gacgatagga aattcgatag agagtcatat agttgcagct
    16981 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    17041 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    17101 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    17161 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    17221 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgctattatt
    17281 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    17341 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    17401 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    17461 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga
    17521 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    17581 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    17641 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    17701 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    17761 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    17821 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    17881 gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    17941 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    18001 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    18061 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    18121 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    18181 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    18241 tgtgaatttt atatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    18301 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    18361 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    18421 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    18481 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    18541 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    18601 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    18661 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc catctatatt
    18721 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    18781 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    18841 tgttgctgaa tatgctaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    18901 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    18961 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    19021 gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata
    19081 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    19141 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    19201 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    19261 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    19321 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    19381 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    19441 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    19501 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    19561 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    19621 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    19681 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    19741 gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg ctgaccattc
    19801 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    19861 ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa
    19921 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    19981 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    20041 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    20101 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    20161 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    20221 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    20281 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    20341 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    20401 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    20461 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    20521 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    20581 ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    20641 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    20701 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    20761 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    20821 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    20881 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    20941 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    21001 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    21061 tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca
    21121 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    21181 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    21241 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    21301 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    21361 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    21421 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    21481 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    21541 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    21601 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    21661 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    21721 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    21781 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    21841 ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa
    21901 aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc
    21961 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    22021 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    22081 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    22141 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    22201 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    22261 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    22321 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    22381 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    22441 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    22501 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    22561 aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa
    22621 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    22681 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    22741 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    22801 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    22861 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    22921 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    22981 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    23041 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    23101 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggt
    23161 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    23221 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    23281 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    23341 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    23401 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    23461 atcgttgaag ttgtagaagg tgacaacaaa tagtaattac ctaggagggc ggggcttagc
    23521 ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt acagctaaac
    23581 ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa aaagcgcttg
    23641 tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa ggtatggcta
    23701 aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt tatgttaacg
    23761 gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca aaaaacgctc
    23821 aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa cctgctaata
    23881 atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct gcatacgtat
    23941 ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg attgaaaaaa
    24001 cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt gttatttcag
    24061 ttgttgaagg tggagacgaa gcacttgcta aacaattgtc aatgcacatc gcagcgatga
    24121 aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat gagttggcac
    24181 aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat aaaccagctc
    24241 ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt gctcaagctg
    24301 aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc tgggacaaaa
    24361 ttatcccagg taaaatggat cgcttcatgc ttgataatac taaagttgac caagcttaca
    24421 cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca taccttgaat
    24481 cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt atcgagaaag
    24541 ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg aataactaat
    24601 aatagaaagg aagcaaattg cttccttttt tgtatagggc ttagattttt cctgaaattg
    24661 ttttttcccc agtctcactc gattagaata attaaaacaa aaagccctat aataagggct
    24721 aagtgcattt aggagactat acttcaaatt catagtaagc gcgtcataac aaggtatcta
    24781 tcctaattcc ccaacttcca gtataccaga taaaaaataa ttatcggagg aaaggtattg
    24841 tactatgata attcaactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga
    24901 tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg aattggatcc
    24961 tttctccgat caagtctttc tcttttgtgg tggacgtaaa gaccgcttta aagttcttta
    25021 ctgggatggt caaggatttt ggatattata taaacgcttt gagaacggaa aactgacttg
    25081 gtccagtaca gaaaaggatg tcaaagctct cacatctgaa caagtagatt ggctgatgaa
    25141 gggcttttct atcactcccc aaatatagtg gatttaaact agaatagtac acctctgctt
    25201 ctaaaacatt gttagaaatc gatttgacta tcctgttctt atttcatttt actataaatt
    25261 catcagaaag tcgtgatttc tattgaaatg aggactttct ttttatactc atctgttttc
    25321 aaaaagcatt ctagtccgtc tccgattaac gatggacttt atcacctcct tctccagtcc
    25381 ttgtatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    25441 tttccacact tgttcaatgg ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc
    25501 aatattagtc ggaatcttta aggtacttga tttatgccat atagcattgt ccataacgag
    25561 taaaagataa tcatctggat aagcttgtga aagctcctat tcctaaagcc cctttagcgc
    25621 ataactttgg ctcagcttct attatcgctc acaccatcca tcagaagttt aatctgaagg
    25681 tacccaatta tcgccaagaa gaagattggg ctaggatggg tttaccaatc acacgtaagg
    25741 aaatctctaa ttggcatatc aagacgagtc aatactattt ggagcccctt tataacctct
    25801 tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct tatagggtgc
    25861 tagagagtga tagtcagctg acttactatt ggactttttt gtctgggaaa gctgagaaac
    25921 aagggattac gctttaccat catgttctaa tcgatttgtt catatcttat ttcaatccat
    25981 tataaatagt gagaaatatc tatcctatct tctagaatgt cttccaaacg tggaaactct
    26041 cgtaaacaaa gaggttttag aggcctattt accatggact aaagttgtac aagaaaagtg
    26101 caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg agatttttca
    26161 atagacttcg ttattggacg gttacaattc ataaagtgct gtagagagat aacgttcacc
    26221 gttatctggt gctagggcaa ggactttttt acctgtacct aattttttgg caacctcgat
    26281 ggctccgtag atagctgcag ctgaggaaat ccctacaagg aagccttctt ttccaccaat
    26341 ttcacgtccg agtgcaagag cgtcatctga tgttacacga acgataccat cataggcttt
    26401 agtatcaagt gtatcaggaa taaatccagc tgagatacct tgaattttgt gaggaccagg
    26461 tttttcacca gatagaatag cagattcatc tgcttctact gcaaaaactt gaatgttaga
    26521 attttctgat ttgagtgcat gagaaacacc agaaatcgtt ccaccagtac ctactccagc
    26581 aacaaaggca tctaatccat ctttaccgaa agcagctagt atctcagctc ctgttgttct
    26641 ttcgtgtact tctggattag ctggattgtc aaattgaaga ggaaggaaac catcacgttc
    26701 agcagcgatt tcttgagcct tagcaatagc acctttcatt ccctcgctac caggagttag
    26761 gacgagttca gcaccataag cttggataat tttacgtcgt tctacactca tagtttcagg
    26821 cataacgatg acgactttat accctttagc agcacctacc catgaaagtc caataccggt
    26881 gtttccactt gttgcttcaa caatagtaga accaggtttc agaataccat cttgttcagc
    26941 tttttcaatc atgctaaggg caatacggtc ttttacagat gaaccaggat taaatgcttc
    27001 aagctttata tagacgtctg cagcaccttc tggcacgatg ttgttaagtt taacaatcgg
    27061 tgtttgaccg attaattcag taatgttgtt ataaatagac atatgaatac ctctttgtat
    27121 aagatatctt tagtataacg ctatccatac catttgtaaa atatagaaat cctatcgaag
    27181 cgataggatt tctatatatc atagatcaaa gtcattaatt ttcaagtgat tgcgttcagc
    27241 taattctagt aaataggtgt gaaggaaaac gatatcaggt ttcgtttgaa ttgcttcatt
    27301 ttctagtata ttttggtacg catcttttta ttttgctcgc taaagtagtt gtgagaatgt
    27361 caacgaaacg ctgtattatt cattgtttac actaagttta caggaacttc aacctctcgt
    27421 aaaccttggt cagttaaagt gacttttcca ttaaaaaact ccacaagtgc agctttaata
    27481 gtttcttttt cttctttatc aacataaatc atcgtatcga cttgatctgt aaagtttgta
    27541 tccagctcca tgagaccatg ttctttaagg aagttactgt actcttggta ctgagcataa
    27601 gacatttgaa tagcaatgcc agcctgttct tttatttcaa taataccaat ttctttgaca
    27661 gctaaggcga cactgccggc gtaagcacga attagtcctc cagcgcctag tttaatacca
    27721 ccaaagtagc gtgtcacgac cacacagaca ttggtgagat tgtgattttc tagtacccca
    27781 agcatgggaa caccagcagt accactaggc tcaccatcat cacttgtacg tttaatttca
    27841 ctacgttctc caataatgaa ggcagagcag ttatgtgtcg ctttgtagtg ttcttttttg
    27901 atggcagtaa tgaagtcacg agcctcttct tcgctataaa cacgcttggc atggcagata
    27961 aagcgagatt ttttgatttc ttcttggact tgaccgtcct ctttaattgt cctaaattcc
    28021 atgatttaat tgtactaaaa aatcatctaa agtgctagtt tttacgaata aagaagtatg
    28081 aaagtaaatt tagattatct cggtcgttta tttactgaga atgaattaac agaagaagaa
    28141 cgtcagttgg cggagaaact tccagcaatg agaaaggaga aggggaaact tttctgtcaa
    28201 cgctgtaata gtactattct agaagaatgg tatttgccca tcggtgctta ctattgtcga
    28261 gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt tatactattt tccgcaggag
    28321 gattttccaa agcaagatgt tctcaaatgg cgcggccaat taactccttt tcaagagaag
    28381 gtgtcagagg gattgcttca agtagtagac aagcaaaagc caaccttagt tcatgcggta
    28441 acaggagctg gaaagacaga aatgatttat caagtagtgg ctaaagtgat caatgcgggt
    28501 ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt tggagctgta caagcgcctg
    28561 caacaggatt tttcttgcgg gatagctttg ctacatggag aatcggaacc ttattttcga
    28621 acaccactag ttgttgcaac aacccatcag ttattgaagt tttatcaagc ttttgatttg
    28681 ctgatagtgg atgaagtaga tgcttttcct tatgttgata atcccatgct ttaccacgct
    28741 gtcaagaata gtgtaaagga gaatggattg agaatctttt taacagcgac ttcgaccaat
    28801 gagttagata aaaaggtccg tttaggagaa ctaaaaagac tgaatttacc gagacggttt
    28861 catggaaatc cgttgattat tccaaaacca atttggttat cggattttaa tcgctactta
    28921 gacaagaatc gtttgtcacc aaagttaaag tcctatattg agaagcagag aaagacagct
    28981 tatccgttac tcatttttgc ttcagaaatt aagaaagggg agcagttagc agaaatctta
    29041 caggagcaat ttccaaatga gaaaattggc tttgtatctt ctgtaacaga ggatcgatta
    29101 gagcaagtac aagcttttcg agatggagaa ctgacaatac ttatcagtac gacaatcttg
    29161 gagcgcggag ttaccttccc ttgtgtggat gttttcgtag tagaggccaa tcatcgtttg
    29221 tttaccaagt ctagtttgat tcagattggt ggacgagttg gacgaagcat ggatagaccg
    29281 acaggagatt tgcttttctt ccatgatggg ttaaatgctt caatcaagaa ggcgattaag
    29341 gaaattcaga tgatgaataa ggaggctggt ctatgaagtg cttgttatgt gggcagacta
    29401 tgaagactgt tttaactttt agtagtctct tacttctgag gaatgatgac tcttgtcttt
    29461 gttcagactg tgattctact tttgaaagaa ttggggaaga gaactgtcca aattgtatga
    29521 aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg gtgtaaagaa ggagttgaag
    29581 tcagtcatag agcgattttt acttacaatc aagctatgaa ggattttttc agtcgctata
    29641 agtttgatgg agacttcctg ttaagaaaag ttttcgcttc atttttaagt gaggagttga
    29701 aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag tcctgataga tatgctaata
    29761 gaggatttaa tcaggttgag ggcttggtag aggcagcagg ctttgagtat ctggatttat
    29821 tagagaaaag agaagagaga gccagttctt ctaaaaatcg ttcagagcgc ttggggacag
    29881 aacttccttt ctttattaaa agtggagtca ctattcctaa aaaaatccta cttatagatg
    29941 atatctatac tacaggagca actataaatc gtgttaagaa actgttggaa gaagctggtg
    30001 ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa aaatttgcaa aaatagaatg
    30061 aaagcgttat aataaaatca taaaaacaaa aatgtttaga aagaaggtac tcatatgatt
    30121 aaatatagta tccgtggtga aaacctagaa gtaacagaag caattcgtga ttatgtagtt
    30181 tctaaactcg aaaagatcga aaagtacttc caaccagaac aagagttgga tgcccgaatt
    30241 aacttaaaag tttatcgtga aaaaacggct aaagtggaag taacgattcc gcttggatct
    30301 attactctcc gcgcagaaga tgtatctcaa gatatgtatg gttcaattga ccttgtaact
    30361 gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa tcgagcgtaa aaataaaaat
    30421 aaggtagcaa ctggtcaatt atttacagat gctttggtgg aagattcaaa tgttgtccag
    30481 tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa tggatttgga agaagcaatt
    30541 ctacaaatgg atttattggg gcatgatttc tttatctatg tggatgttga agatcagaca
    30601 accaatgtga tttatcgtcg tgaggatggc gaaattggtt tgttagaggt taaagaatct
    30661 taatttcaat atgtgtaaag gtaggtttac tgaattgtaa actacctttt tcttataatt
    30721 gatagaatta ctgattacac ttttaaaaag tcgctttttg aggggtatta tggtataatg
    30781 ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc caatttttcc tattctagta
    30841 ggattgattg cgtttggagt cttatccact ttcattattt ttgttaataa taatctgttg
    30901 acggttttaa ttttgtttct ttttgtagga ggctatgttt ttttatttaa gaaactgaga
    30961 gtgcattata caaggagtga tgtagaacag atacagtatg taaaccacca agcggaagaa
    31021 agtttgacat ctctattgga acaaatgcct gtaggtgtta tgaaattgaa tttatcttct
    31081 ggagaggttg agtggtttaa tccctatgct gaattgattt tgaccaagga agatggtgat
    31141 tttgatttag aagctgttca aacgattatc aaggcttcag taggaaatcc gtctacttat
    31201 gccaagcttg gtgagaagcg ttatgctgtt catatggatg cttcttccgg tgttttgtat
    31261 tttgtagatg tatccaggga acaagccata acagatgaat tggtaacaag tcgaccagtg
    31321 attgggattg tctctgtgga taattatgat gatttggagg atgcaacttc tgagtcagat
    31381 attagtcaaa tcaatagttt tgtagctaat tttatatcag agttttcaga aaaatacatg
    31441 atgttttctc gtcgggtaag tatggatcga ttttatctat ttactgacta cacggtgctt
    31501 gagggcttga tgaatgataa attttctgtt attgatgctt tcagagaaga gtcgaaacag
    31561 agacagttgc ccttgacctt aagtatggga ttttcttatg gcgatggaaa tcatgatgag
    31621 atagggaaag ttgctttgct caatttgaac ttggctgaag tacgtggtgg cgaccaggtg
    31681 gttgttaagg aaaacgacga aacgaaaaat ccagtttatt ttggtggtgg gtctgctgct
    31741 tcaatcaagc gtacacggac tcgtacgcgc gctatgatga cagctatttc agataagatt
    31801 cggagtgtag atcaggtttt tgtagtcggt cacaaaaatt tagacatgga tgctttgggc
    31861 tctgctgtag gtatgcagtt gttcgccagc aatgtgattg aaaatagcta tgctctttat
    31921 gatgaagaac aaatgtctcc agatattgaa cgagctgttt cattcataga aaaagaagga
    31981 gttacgaagt tgttgtctgt taaggatgca atggggatgg tgaccaatcg ttctttgttg
    32041 attcttgtag accattcaaa gacagcctta acattatcaa aagaatttta tgatttattt
    32101 acccaaacca ttgttattga ccaccataga agggatcagg attttccaga taatgcggtt
    32161 attacttata tcgaaagtgg tgcaagtagt gccagtgagt tggtaacgga attgattcag
    32221 ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag caagtgtctt gatggctggt
    32281 atgatgttgg atactaaaaa tttcacctcg cgagtaacta gtcggacatt tgatgttgct
    32341 agctatctca gaacgcgcgg aagtgatagt attgctatcc aggaaatcgc tgcgacagat
    32401 tttgaagaat atcgtgaggt caatgaactt attttacagg ggcgtaaatt aggttcagat
    32461 gtactaatag cagaggctaa ggacacgaaa tgctatgata cagttgttat tagtaaggca
    32521 gcagatgcca tgttagccat gtcaggtatt gaagcgagtt ttgttcttgc gaagaataca
    32581 caaggattta tctctatctc agctcgaagt cgtagtaaac tgaatgtaca acggattatg
    32641 gaagagttag gcggtggagg ccactttaat ttggcagcag ctcaaattaa agatgtaacc
    32701 ttgtcagaag caggtgaaaa actgacagaa attgtattaa atgaaataaa ggaaaaggag
    32761 aaagaagaat gaaagtaatc tttttagcag atgttaaagg aaaaggtaaa aaaggcgaaa
    32821 ttaaggaagt accaacaggg tatgcgcaaa actttcttat caaaaagaat ctagccaaag
    32881 aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca aaaatcggaa gaaaaagctc
    32941 acgctgagat gattgcagaa ggaaaagcaa ttaaagcaca acttgaagca gaagaaactg
    33001 ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac ctttggttct attaccaata
    33061 agaagattgc agaagaattg caaaagcaat ttggaattaa gattgataaa cgtcatattc
    33121 aagtacaagc tccgattcga gcggttggtt tgattgatgt gccagtgaaa atctatcaag
    33181 atatcacaag tgtaatcaat cttcgtgtga aagaaggata agtttacacc ttcttgacaa
    33241 gattgtaaaa ggaagggaag tctgatggca gaagtagaag agttacgagt acaacctcaa
    33301 gatatcttag ctgagcaatc cgttttaggg gctatcttta ttgatgagag taaacttgtt
    33361 tttgtgcgag aatacattga gtctcgggac ttttttaagt atgcccatcg tttgattttc
    33421 caagccatgg tcgatttatc cgatcgtggt gatgccatag atgcaacaac ggttcgtact
    33481 atccttgata atcaaggtga tttacagaat attggtggct tgtcttactt ggttgagatt
    33541 gttaattctg tgccaacttc tgctaatgcg gagtattatg ctaagattgt tgcagaaaaa
    33601 gcaatgctac gtcgtttaat tgccaagttg acagagtctg tcaaccaagc ttacgaagcg
    33661 tcacaaccag ctgatgaaat tattgctcag gcagaaaaag ggttgattga tgtcagtgaa
    33721 aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt tgaatctcaa ctttggaaat
    33781 ctggaagctc gctcgcaaca aacgaccgat attacaggta ttgcgacagg ttatcgtgat
    33841 ttggatcata tgacaacagg acttcatgag gaggagttga ttatcttagc agctcgtcca
    33901 gcagttggta agacagcatt tgccttgaat atcgctcaga atattgggac taagttggac
    33961 aaaacggttg ctattttttc actcgaaatg ggtgcggaaa gcttggtaga ccgtatgtta
    34021 gctgcagaag gcttagtgga gtcacattct atccgtacag ggcaattgac agatgaggag
    34081 tggcaaaaat atactattgc tcagggtaat ctagctaacg ccagtatcta tatcgatgat
    34141 acgccaggta ttcggattac agagattcgt tctcgttctc gtaaattggc tcaagaaact
    34201 ggaaatcttg gtttgatttt gatagactat ttgcaactta tcacgggaac tggtcgagaa
    34261 aatcgtcaac aagaagtttc tgaaatttct cgtcagttga aaatactagc caaggaattg
    34321 aaggttccag taatcgctct gagtcagctt tctcgtggtg tagaacaacg tcaggacaag
    34381 agaccggtct tgtctgatat tcgtgaatct gggtctattg agcaggacgc tgatatcgta
    34441 gcttttctct atcgcgatga ctactatgaa cgtggtggtg aagaagagga gggtatccca
    34501 aataataagg tggaagttat tatcgagaaa aaccgtagtg gagctcgtgg aacagtggaa
    34561 ttgattttcc aaaaagaata caataaattt tcaagtatct caaagaggga ggcataagat
    34621 gtcagatgca tttacagatg tagccaagat gaaaaaaatc aaagaagaaa tcaaggcaca
    34681 tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt aagcgccaaa aaaatagatt
    34741 gggtaagcta attgaagttt atccatctct atttattgtg gagtttgggg atgtggaagg
    34801 agataaacaa gttaatgttt acgttgaatc ctttacttac tcagatattc ttacagaaaa
    34861 gaatttgatt cattatcttg actaaagtga gaaattttct cactttttct tttttctccg
    34921 aataatttag gtgaaggcaa tcatcgcttt atattatttt ttaaggagga agaatgaaaa
    34981 ttttaccgtt tatagcaaga ggaacaagtt attacttgaa gatgtcagtt aaaaagcttg
    35041 ttcctttttt agtagtagga ttgatgctag cagctggtga tagtgtctat gcctattcca
    35101 gaggaaatgg atcgattgcg cgtggggatg attatcctgc ttattataaa aatgggagcc
    35161 aggagattga tcagtggcgc atgtattctc gtcagtgtac ttcttttgta gcctttcgtt
    35221 tgagtaatgt caatggtttt gaaattccgg cagcttatgg aaatgcgaat gaatggggac
    35281 atcgtgctcg tcgggaaggt tatcgtgtag ataatacacc gacgattggt tccattactt
    35341 ggtctactgc aggaacttat ggtcatgttg cctgggtgtc aaatgtaatg ggagatcaga
    35401 ttgagattga ggaatataac tatggttata cagaatccta taataaacga gttataaaag
    35461 caaacacgat gacaggattt attcatttta aagatttgga tggcggcagt gttgggaata
    35521 gtcaatcctc agcttcaaca ggcggaactc attattttaa gaccaagtct gctattaaaa
    35581 ctgaacccct agctagcgga actgtgattg attactatta tcctggggag aaggttcatt
    35641 atgatcagat acttgaaaaa gacggctata agtggttgag ttatactgcc tataatggaa
    35701 gctatcgtta tgttcaattg gaggctgtga ataaaaatcc tctaggtaat tctgttcttt
    35761 cttcaacagg tggaactcat tattttaaga ccaagtctgc tatcaaaact gaacccctag
    35821 ttagcggaac tgtgattgat tactattatc ctggagagaa ggttcattat gatcagatac
    35881 ttgaaaaaga cggctacaag tggttgagtt atactgccta taatggaagt cgtcgctata
    35941 tacagctaga gggagtgact tcttcacaaa attatcagaa tcaatcagga aatatctcta
    36001 gctatggatc caataatagt tcaactgtcg gttggaagaa aataaatggt agttggtatc
    36061 atttcaaatc aaatggttct aaatcaacag gatggctgaa agacggttct agctggtatt
    36121 atttgaaatt atctggtgaa atgcagacag gatggttaaa ggagaatggc tcgtggtatt
    36181 atctgggtag ttcaggggca atgaaaacag gctggtacca ggtctctggt aagtggtatt
    36241 attcttactc ttcaggcgcc ttagctgtta atacgacggt ggatggctac agagtaaaca
    36301 gtgatggaga acgagtatag aaaattggag taggagaaat ttcctgctct tttctgtaag
    36361 cagtttcctt gacatttttc ttattttgcg ctatcatata tacatataat atatgggagt
    36421 ctgtgtacag tctgagagga agtgttaaac ttcgaccgca cctgatctgg gtaatgccag
    36481 cggagggaac gatacttagt ctaattttgc accttttcca tgtatggtaa aggtttttct
    36541 ttttttaaaa aggaaaacga gaagaggagg ttcttatgaa agcaagcatt gccttgcaag
    36601 ttttacccct agcacagggg attgatcgga tagctgttat tgatcaggtc attgcttatc
    36661 tgcaaactca agaagtgacg atggtagtga caccatttga aacggtcttg gaaggggagt
    36721 ttgatgagct tatgcgcatt ctaaaagaag cgctggaagt ggcagggcag gaggcagaca
    36781 atgtctttgc caatgtcaaa ataaatgtag gagagatttt aagtattgat gagaaacttg
    36841 agaagtatac tgagacgaca cattagtcta ttgggctttc tcggagtctt gttaatctgg
    36901 cagttagcag gttttcttaa acttctcccc aagtttatcc tgccgacacc tcttgaaatt
    36961 ctccagccct ttgttcgtga cagagaattt ctctggcacc atagctgggc gaccttgaga
    37021 gtggctttac tggggctgat tttgggagtt ttgattgcct gtcttatggc tgtgctcatg
    37081 gatagtttga cttggctcaa tgacctgatt taccctatga tggtggtcat tcagaccatt
    37141 ccgaccattg ccatagctcc tatcctggtc ttgtggctag gttatgggat tttgcccaag
    37201 attgtcttga ttatcttaac gacaaccttt cccatcatcg ttagtatttt ggacggtttt
    37261 aggcattgcg acaaggatat gctgaccttg tttagtctga tgcgggccaa gccttggcaa
    37321 atcctgtggc attttaaaat cccagttagc ctgccttact tttatgcagg tctgagggtc
    37381 agtgtctcct acgcctttat cacaactgtg gtatctgagt ggttgggagg ttttgaaggt
    37441 cttggtgttt atatgattca gtctaaaaaa ttgtttcagt atgataccat gtttgccatt
    37501 attattctgg tgtcgattat cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa
    37561 tatgtgatta aatggaaacg ttcgtagaat tagaatgttt ctgaaaaaga aaagaggaaa
    37621 tcaaaatgaa gaaaacatgg aaagtgtttt taacgcttgt aacagctctt gtagctgttg
    37681 tgcttgtggc ctgtggtcaa ggaactgctt ctaaagacaa caaagaggca gaacttaaga
    37741 aggttgactt tatcctagac tggacaccaa ataccaacca cacagggctt tatgttgcca
    37801 aggaaaaagg ttatttcaaa gaagctggag tggatgttga tttgaaattg ccaccagaag
    37861 aaagttcttc tgacttggtt atcaacggaa aggcaccatt tgcagtgtat ttccaagact
    37921 acatggctaa gaaattggaa aaaggagcag gaatcactgc cgttgcagct attgttgaac
    37981 acaatacatc aggaatcatc tctcgtaaat ctgataatgt aagcagtcca aaagacttgg
    38041 ttggtaagaa atatgggaca tggaatgacc caactgaact tgctatgttg aaaaccttgg
    38101 tagaatctca aggtggagac tttgagaagg ttgaaaaagt accaaataac gactcaaact
    38161 caatcacacc gattgccaat ggcgtctttg atactgcttg gatttactac ggttgggatg
    38221 gtatccttgc taaatctcaa ggtgtagatg ctaacttcat gtacttgaaa gactatgtca
    38281 aggagtttga ctactattca ccagttatca tcgcaaacaa cgactatctg aaagataaca
    38341 aagaagaagc tcgcaaagtc atccaagcca tcaaaaaagg ctaccaatat gctatggaac
    38401 atccagaaga agctgcagat attctcatca agaatgcacc tgaactcaag gaaaaacgtg
    38461 actttgtcat cgaatctcaa aaatacttgt caaaagaata cgcaagcgac aaggaaaaat
    38521 ggggtcaatt tgacgcagct cgctggaatg ctttctacaa atgggataaa gaaaatggta
    38581 tccttaaaga agacttgaca gacaaaggct tcaccaatga atttgtgaaa taatgacaga
    38641 aattagacta gagcacgtca gttatgccta tggtcaggag aggattttag aggatatcaa
    38701 cctacaggtg acttcaggcg aagtggtttc catcctaggc ccaagtggtg ttggaaagac
    38761 caccctcttt aatctaatcg ctgggatttt agaagttcag tcagggagaa ttgtccttga
    38821 tggtgaagaa aatccccagg ggcgcgtgag ttatatgttg caaaaggatc tgctcttgga
    38881 gcacaagacg gtgcttggaa atatcattct gcccctcttg attcaaaagg tggataaggc
    38941 agaagctatt tcccgagcgg ataaaattct tgcgaccttc cagctgacag ctgtaagaga
    39001 caagtatcct catgaactta gcggtgggat gcgccagcgt gtagccttac tccggaccta
    39061 cctttttggg cacaagctct ttctcttaga tgaggccttt agcgccttgg atgagatgac
    39121 aaagatggaa ctccacgctt ggtatcttga gattcacaaa cagttgcagc taacaactct
    39181 gatcatcacg catagtattg aggaggccct caatctcagc gaccgcatct atatcttgaa
    39241 aaatcgccct gggcagattg tttcagaaat taaactagat tggtctgaag atgaggacaa
    39301 ggaagtccaa aagattgcct acaaacgtca aatcttggca gaattaggct tagaataagt
    39361 agaaaaatag ggagttggtg aagattatcc tttaccagcg ccctttttct tttaaaaatg
    39421 agaaaatttc ggtataatag tcaaacaagg tcaaggttta aagagagagg tgggtttgtt
    39481 atgagattta aaaatacatc ggatcatatt gaggcctaca tcaaggcgat tttagatcaa
    39541 tctggtatcg tggagttgca acggagtcag ttggcagata cctttcaggt tgttcctagt
    39601 cagattaact acgtgatcaa gacacgcttt acggaaagta gaggctactt ggttgaaagt
    39661 aagcgtggtg gcggaggcta cattcgtata ggacggattg agttttctag tcatcatgaa
    39721 atgctccggg atctgcttta ctcgattggt gagcgagtca gtcaagaaat ttatgaggat
    39781 attctccagc ttttggttga gcaggaattg atgaccaagc aggagatgaa tttgctagaa
    39841 tcagtagctt tggatcgcgt tttaggagaa gaagctccag ttgttcgagc aaacatgcta
    39901 cgtcaggtca tacaagaggt agatagaaaa gggaagtaag atgaactatt caaaagcatt
    39961 gaatgaatgt atcgaaagtg cctacatggt tgctggacat tttggagctc gttatctaga
    40021 gtcgtggcac ttgttgattg ccatgtctaa tcacagttat agtgtagcag gggcaacttt
    40081 aaatgattat ccgtatgaga tggaccgttt agaagaggtg gctttggaac tgactgaaac
    40141 ggactatagc caggatgaaa cctttacgga attgccgttc tcccgtcgtt tgcaggttct
    40201 ttttgatgaa gcagagtatg tagcgtcagt ggtccatgct aaggtactag ggacagagca
    40261 cgtcctctat gcgattttgc atgatggcaa tgccttggcg actcgtatct tggagagggc
    40321 tggtttttct tatgaagaca agaaagatca ggtcaagatt gctgcccttc gtcgaaattt
    40381 agaagaacgt gcaggctgga ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac
    40441 agtagctgac aagcaaaatt ctatggccaa tatgatgggc atgccgcaga ctcctagtgg
    40501 tggtctcgag gactatacgc atgatttgac agagcaagcg cgttctggca agttagaacc
    40561 agtcatcggt cgggacaagg aaatctcacg tatgattcaa atcttgagcc gtaagactaa
    40621 gaacaaccct gtcttggttg gggatgctgg tgtcgggaaa acagctctgg cccttggtct
    40681 tgcccagcgt attgctagtg gtgacgtgcc tgcggaaatg gctaagatgc gcgtgttaga
    40741 acttgatttg atgaatgtcg ttgcagggac acgcttccgt ggtgactttg aagaacgcat
    40801 gaataatatc atcaaggata ttgaagaaga tggccaagtc atcctcttta tcgatgaact
    40861 ccacaccatc atgggttctg gtagcgggat tgattcgact ctggatgcgg ccaatatctt
    40921 gaaaccagcc ttggcgcgtg gaactttgag aacggttggt gccactactc aggaagaata
    40981 tcaaaaacat atcgaaaaag atgcggcact ttctcgtcgt ttcgctaaag tgacgattga
    41041 agaaccaagt gtggcagata gtatgactat tttacaaggt ttgaaggcga cttatgagaa
    41101 acatcaccgt gtacaaatca cagatgaagc ggttgaaaca gcggttaaga tggctcatcg
    41161 ttatttaacc agtcgtcact tgccagactc tgctatcgac ctcttggacg aagcagcagc
    41221 aacagtgcaa aataaggcaa agcatgtaaa agcagacgat tcagatttga gtccagctga
    41281 caaggccctg atggatggca agtggaaaca ggcagcccag ctaatcgcaa aagaagagga
    41341 agtacctgtc tacaaagact tggtgacaga gtctgatatt ttgaccacct tgagtcgctt
    41401 gtcaggaatc ccagttcaaa agctgactca gactgacgct aagaaatatc taaatcttga
    41461 agcagaactc cataaacggg ttatcggtca agatcaagct gtttcaagta ttagtcgtgc
    41521 gattcgccgt aatcagtcag gaattcgcag tcacaagcgt ccgatcggtt cctttatgtt
    41581 cctaggaccc acaggtgtcg gtaagaccga gttggccaag gctttggcag aagttctctt
    41641 tgatgacgaa tcagccctta tccgctttga tatgagtgag tatatggaga aattcgcagc
    41701 cagccgtcta aatggagctc ctccaggcta tgtgggttac gaagaaggtg gggagttgac
    41761 agagaaggtt cgcaataaac cctattccgt tctcctcttt gatgaggtag agaaggctca
    41821 cccagatatc tttaatgttc tcttgcaggt tctggatgac ggtgtcttga cagatagcaa
    41881 gggacgcaag gtcgattttt caaataccat tatcattatg acatcgaacc taggtgcgac
    41941 tgcccttcgt gatgataaga ctgttggttt tggggctaag gatattcgtt ttgaccagga
    42001 aaatatggaa aaacgcatgt ttgaagaact gaaaaaagct tatagaccgg aattcatcaa
    42061 ccgtattgat gagaaggtgg tcttccatag cctatctagt gatcatatgc aggaagtggt
    42121 gaagattatg gtcaagcctt tagtggcaag tttggctgaa aaaggcattg acttgaaatt
    42181 acaagcttca gctctgaaat tgttagcaaa tcaaggatat gacccagaga tgggagctcg
    42241 cccacttcgc agaaccctgc aaacagaagt ggaggacaag ttggcagaac ttcttctcaa
    42301 gggagattta gtggcaggca gcacacttaa gattggtgtc aaagcaggcc agttaaaatt
    42361 tgatattgca taaaagaata aaagtaccag catctgacca taagtcacag tggagtgaaa
    42421 ctcaatgaaa atcaaagagc aaactaggca gctagccgca ggttgctcaa aacactgttt
    42481 tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat aagctgcaag
    42541 atgaatgatt ttcttgtatt gacgttgttg ttgacaaaaa gtagcggata aatgaaatcc
    42601 attctattat catagatgat aggctggtag gaaattttca aatagcatac aggaaataga
    42661 tgtatggagt tctggtagta gaaagggaga gagatgaaca ttttagttgc agatgacgag
    42721 gaaatgatta gagaaggaat tgcagcattt ctgacagaag agggttatca tgtcattatg
    42781 gctaaggatg gacaagaggt cttggaaaaa tttcaagatc tccctatcca tctcatggta
    42841 ctggatttaa tgatgcctag gaagagtggt tttgaagtgt taaaagaaat caatcaaaag
    42901 cacgatattc ctgtcatcgt cttgagtgct ctgggagatg aaattactca gtcacaggta
    42961 tttgatctct atgctgatga tcatgtgaca aaaccttttt ctttggtact gcttgtcaag
    43021 cgtattaagg cgcttatcag acgttactac gtcatagagg atatttggcg atatcaggat
    43081 gtaacagtgg attttacctc ttacaaagca cattataaaa atgaagaaat tgatctcaaa
    43141 ccaaaggaat tactggtact aaagtgtttg attcagcata aaaatcaagt tttaagtaga
    43201 gagcagatat tggaagaaat ttcaaaagat gtagctgatt taccttgtga tagggtcgtt
    43261 gatgtctata ttcgtactct tcgcaaaaaa ttagctttag attgtatcgt gactgtgaaa
    43321 aatgttgggt ataagattag tttatgataa aaaatcctaa attattaacc aagtcctttt
    43381 taagaagttt tgcaattcta ggtggtgttg gtctagtcat tcatatagct atttatttga
    43441 cctttccttt ttattatatt caactggagg gggaaaagtt taatgagagc gcaagagtgt
    43501 ttacggagta tttaaagact aagacatctg atgaaattcc aagcttactc cagtcttatt
    43561 caaagtcctt gaccatatct gctcacctta aaagagatat tgtagataag cggctccctc
    43621 ttgtgcatga cttggatatt aaagatggaa agctatcaaa ttatatcgtg atgttagata
    43681 tgtctgttag tacagcagat ggtaaacagg taacagtgca atttgttcac ggggtggatg
    43741 tctacaaaga agcaaagaat attttgcttt tgtatctccc atatacattt ttggttacaa
    43801 ttgctttttc ctttgttttt tcttattttt atactaaacg cttgctcaat cctctttttt
    43861 acatttcaga agtgactagt aaaatgcaag atttggatga caatattcgt tttgatgaaa
    43921 gtaggaaaga tgaagttggt gaagttggaa aacagattaa tggtatgtat gagcacttgt
    43981 tgaaggttat ttatgagttg gaaagtcgta atgagcaaat tgtaaaattg caaaatcaaa
    44041 aggtttcctt tgtccgcgga gcatcacatg agttgaaaac ccctttagcc agtcttagaa
    44101 ttatcctaga gaatatgcag cataatattg gagattacaa agatcatcca aaatatattg
    44161 caaagagtat aaataagatt gaccagatga gccacttatt ggaagaagta ctggagtctt
    44221 ctaaattcca agagtggaca gagtgtcgtg agactttgac tgttaagcca gttttagtag
    44281 atattttatc acgttatcaa gaattagctc attcaatagg tgttacaatt gaaaatcaat
    44341 tgacagatgc taccagagtc gtcatgagtc ttagggcatt ggataaggtt ttgacaaacc
    44401 tgattagtaa tgcaattaaa tattcagata aaaatgggcg cgtaatcata tccgagcaag
    44461 atggctatct ctctatcaaa aatacatgtg cgcctctaag tgaccaagaa ctagaacatt
    44521 tatttgatat attttatcat tctcaaatcg tgacagataa ggatgaaagt tccggtttgg
    44581 gtctttacat tgtgaataat attttagaaa gctatcaaat ggattatagt tttctccctt
    44641 atgaacacgg tatggaattt aagattagct tgtagacaga ttagtttttt attaaagttc
    44701 atatagggtt aacataagtg tgttattctt tgtgtagata aaagaaagga tactaatatg
    44761 gtattagcga ttattttagt aacattcttt attcgattga tttttttaaa gcgttcgata
    44821 gagaatgaga aacgaatcct tagcaatggc gggaaagaat ttggagttga gaatacaaaa
    44881 cgattaacta tggctcatat tgttttttat ctctcttgct tggttgaggc aatggtgcac
    44941 aagacaattt ttgatggcat gggcatggtt ggtttagtct tgcttatttt ttctatgctg
    45001 atgttgatgt tggtgattca cttgttggga gatatttgga cagtgaagct tatgcttgtc
    45061 aataatcaca aatatgtaga tcatatcttg tttaggacag taaaacaccc taattacttt
    45121 ttaaatattt tacctgagtt gattggcttg accttgttga gtcatgccta tatgactttt
    45181 gttttagttt ttccagttta tgcagttatt ttgtatcgac gaatagctga agaggaaaag
    45241 ctattacatg aagttataat cccaaatgga agcataaaga gataaataca aaattcgact
    45301 catatacagt tcatattgaa gtgatatagt aaggttaaag aaaaaatata gaaggaaata
    45361 aacatgtttg catcaaaaag cgaaagaaaa gtacattatt caattcgtaa atttagtatt
    45421 ggagtagcta gtgtagtagt tgccagcttg ttcttaggag gagtagtcca tgcagaaggg
    45481 gttaggagta agaataacct cacggttaca tctagtgggc aagatatatc gaagaagtat
    45541 gctgatgaag tcgagtcgca tctacaaagt atattgaagg atgtcaataa aaatttgaaa
    45601 aaagttcaac atacccaaaa tgtcgacttc aacaaaaagt tgagcagaat taaaacgaag
    45661 tatttgtatg gattaaaaga gaagtcggaa gctgagttga cgttaaaaac aaaagaaaca
    45721 aaagaagagt taaccgcagc ttttgagcag tttaaaaaag atacattgaa atcaggaaaa
    45781 aaggtagcag aagctgagaa aaaagccaaa gctcaaaaag aagaagatcg ccgtaactac
    45841 ccaaccaata cttacaaaac aatcgaactg gaaattgcgg aagcagaagt aggggtcgcc
    45901 aaggcagagc ttgagcttga gtttgcacaa gctcaagttc aaatacctca agatactgag
    45961 aaaattaatg ctgctaaatc taaagtagaa gctgctaaaa gtaatgttaa aaaactagaa
    46021 aaaattaaat cagatattga aaaaacgtat ttgtataaat tagataactc aaccaaagaa
    46081 acgccaaaac ctagagtgcg aagaaattct ccggaaataa aagctaaggg cagagtcaaa
    46141 aattatgaag aggctaatat tgaactttct aaatatatga ctgatttgta taaattagat
    46201 aactcaacca aagaaacgcc aaaatctaga gtgcgaagaa attctccgca agtaggcgat
    46261 tcgagagaac ttaaggaaac gatagacaaa gcgaaagaaa ctctgtctac ctatatggta
    46321 actcgtttaa cgaagctgga tccatctgtt ttttggtttg cagatcttct tatggatgct
    46381 aagaaggttg tggaagaata caagacaaaa ttagaggatg cttcagataa aaaatcggta
    46441 gaagacttgc gaaaggaagc agaaggaaaa atagagtctc ttatcgtgac tcaccaaaat
    46501 agagaaaaag aaaaccaacc agcaccccaa ccaggaggac aagcaggtgg ttcaatggtt
    46561 gtaccaccgg tgacgcaaac acctccatca acttcccaaa gtccaggaca aaaggcgacc
    46621 gaagctgaaa agaaaaagtt acaagacttg attcgtcaat tccaagaagc cttgaacaaa
    46681 ctagacgatg aaacaaagac tgttccagat ggggctaaac tcacaggaga agctggaaaa
    46741 gcctataatg agactagaac ttatgcgaaa gaagttgttg acaaaagcaa gaagcttcta
    46801 tcacagacag cagtgacaat ggatgaattg gcaatgcaat taaccaaatt gaacgatgcc
    46861 atgtctaaat tgaaagaagc taaagcgaaa ttggtaccag aggttaaacc acagccggaa
    46921 aacccagagc caaaaccaca accagagggt gagaaaccaa gcgtaccaga tattaatcag
    46981 gagaaagaaa aagctaaact tgctatagca acatacatga gcaagatttt agatgatata
    47041 aagaaacatc atctgaagaa agaaaaacat catcagattg ttgctcttat taaggacctt
    47101 gataaactta aaaagcaagc actttctgaa attgataatg taaataccaa agtagaaatt
    47161 gagaatacag tccacaaggt atttgcagac atggatacgg ttgttactaa attccaaaaa
    47221 ggcttaattc agaacacacc gcaggttcca gaagcaccaa agagcccaga ggtaccaaag
    47281 gtttcagata caccaaaggc tccggacaca ccgcaggttc cagaagcacc aaagagccca
    47341 gaggtaccaa aggttccaga agcaccaaag gctccagaca caccgcaagt tccggaagca
    47401 ccaaagagcc cagaggtacc aaaggttcca gatacaccaa aggctccgga cacaccgcaa
    47461 gttccagaag caccaaagag cccagaggta ccaaaggttc cagatacacc aaaggctccg
    47521 gacacaccgc aggttccaga agcaccaaag gctccagaca caccgcaaat tccggaagca
    47581 ccagctccag aaactccggc tccagctcca gaagctccaa aaacaggctg gaaacaagaa
    47641 aacggtatgt ggtacttcta caatactgat ggttcaatgg caacaggctg gctagaatac
    47701 aatggctcat ggtactatct caacgctaat ggtgctatgg caacaggttg gctagaatac
    47761 aatggttcat ggtactacct caatactaat ggtgctatgg agacaggttg gctagaatac
    47821 aatggttcat ggtactacct caatactaat ggtgctatgg agacaggttg gctagaatac
    47881 aatggttcat ggtactacct aaatgctaac ggttcgatgg caacaggttg gctgaaagat
    47941 ggagatacat ggtactatct tgaagcatca ggggctatga aagaaagcca atggttcaaa
    48001 gtatcagaca aatggtacta tgtcaatggc tcaggtgccc ttgcagtcaa cacaactgta
    48061 ggtggctata gagtcaatgc caatggtaaa tgggtaaact aaacctaatg taactcgtta
    48121 atgctggctt cctgtaagaa ctctttaaag tattccctac aaataccata tcctttcagt
    48181 agatactata cccttgtagg aagtttagat taaaaaataa ctctgtaatc tctagccgga
    48241 tttatggcgc tagagactac ggagtttttt tgatgaggaa agaatggcgg cactcaagag
    48301 actctttaag agagttacgg gttttaaact attaagcctt ctccaattgc aagagagctt
    48361 caatctctgc cagggtgcta gcttgtgaaa tggctccacg gagtttggca gcgccagatg
    48421 ttccacggag atagtgagga gcgaggccgc ggaattcacg aacggcgacg ttttctcctt
    48481 tgaggttaat caatcgtttc aagtgttcgt aggcgatctt catcttgtct tcaaaggtca
    48541 aatcaggtag gatttctcct gtttcaaagt aatggttgat ttggttgaag aggtaaggat
    48601 ttcccatggc agctcggcca atcatgactg cgtcagcacc aacttcttcg atgcgttgct
    48661 tggcttcttg gacagtacgg atatcaccgt tggcgatgaa tggaatcttg gttagagctt
    48721 gggcaacctt gtaaagggtc tcaaggtctg cgtggccagt atacatttgt tcacgggtac
    48781 ggccatgcat ggcgagggca gaaacacctg cagcttcagc agcgagggca ttttctactg
    48841 ccagagatgg gtccgcccat ccggtacgca ttttgacagt aagggggata tcaaggacag
    48901 actgaacctt gttgatgata gagtagatct tgtcaggatc cttgagccac atagctccag
    48961 cttcgttctt cacgattttg ttgacagggc agcccatgtt gatatcgacg atatcggtct
    49021 tggtgttttc ttggatgaat tctgctgcgc gtgctaggct gtcttcatcg ctaccaaaaa
    49081 gttggataga gacagggttt tcgccctcat cgatatgaag catgtgcagg gttttttcgt
    49141 tgttgtattg gattcctttg tcagagacca tttccattac aacgagtcca gctccgagct
    49201 cttttgcgat ggtacgaaag gctgagttgg tcacgccagc cataggcgct aaaacggtac
    49261 gattgggaat ctcaacattg ccaatcataa aaggtgtatt aagatttgtc acgaatgagt
    49321 tcctccaggt ccttttcatc aaagttgtaa gtagtttggc agaattgaca agtgatttct
    49381 gccccgtggt cttcttcttt catttcctgt aagtctgagc ttggaaggct ggcaagagcg
    49441 ttcataaagc gttcatggct acagtcacat tggaaacgga tttcttcttc agaaagacgc
    49501 ttgtaggctt cgtccccgta gatagccttg aggagggctt cgatatggtc gtcgctttcg
    49561 agaagagtag agatagctgg catttcttgg atgcgttttt caaagcgagc aatctcttct
    49621 ttcttggctc ctggcaagac ttgaactagg aaaccacctg caaccttgac cttgtcttcc
    49681 tcgtccaaaa ggacattgag gccgaccgct gaaggcgttt gttggctttc agtaaggtaa
    49741 aaggcaaggt cttcaccgat ttctccggag atgaggggag ttatagagtt gtaaggattt
    49801 ccagtaccgt agtctgtgat aacgaggaat tgaccatttc caacaaaagg tccgactagg
    49861 acttcaccag tcgcagtctt tttgatgtca acaccaggat tttgaacgta gcctttgacg
    49921 ttccccttgg tatcagcgac ggtgataata gcacctagag agctagatcc caacacctta
    49981 actgtaagtt tggtatttcc tttttcattg gctgcgagaa tctggctagc gataagagtt
    50041 cgaccaagcg ctacagttga gctagcttgg gtttggtgtt tttcttgagc agtgcggacg
    50101 gtttccgtgc tgtcaaggac aaaagcacga aaggctccgc tttctgatat agttttaata
    50161 attttattca tagctactat tttagcataa aaatgcccag agggggagcc gtgtgtttac
    50221 tgattttcag gataatggac caggaaatca gcatgaaaat aaaaagagaa acagattatt
    50281 tcagcatttg taagatttat gctatgctta aggtagaaaa tgaaaggggt aacaaatgta
    50341 tttaggagat ttgatggaga aagctgagtg tggtcaattt tcaatccttt cctttctatt
    50401 acaagagtct cagacgaccg tcaaggctgt aatggaagaa acaggatttt caaaagcaac
    50461 cctaaccaaa tatgtcaccc tgctcaatga caaggctttg gatagtggct tagagctgac
    50521 tattcactca gaaaatgaaa atttgcgtct gtctatcggt gcagctacca aggggagaga
    50581 tattcggagc ttatttttgg agagtgctgt taaataccag attttggttt atcttctcta
    50641 ccaccaacag tttttagccc atcagctggc tcaagaattg gtgattagcg aggctacgct
    50701 tggtcgtcac ttggctggtt taaatcagat tctgtcagaa tttgatttat ccatccaaaa
    50761 tggacgttgg cgaggtccag agcatcagat tcgctatttc tatttctgtc ttttccgaaa
    50821 ggtctggtcg agtcaggaat gggaaggtca catgcagaaa ccagagagaa aacaggagat
    50881 tgccaattta gaggaaatct gcggtgcaag tttgtctgtg gggcagaaat tggacttggt
    50941 tctctgggct cacatcagtc aacaacgtct tcgggtcaat gcttgtcagt ttcaagtcat
    51001 agaagagaaa atgcgagggt attttgacaa tatcttttat cttcgtttgc tgagaaaggt
    51061 tccgtccttt tttgctgggc aacatattcc actaggagtt gaggatggtg agatgatgat
    51121 attcttctct tttctcctat ctcatcgcat tcttcctctt catactatgg agtatattct
    51181 tggttttgga gggcagttgg cagatttact gacgcaattg attcaagaaa tgaagaagga
    51241 ggaactattg ggggattata cagaggacca tgtcacctat gaactcagtc agctttgtgc
    51301 tcaagtctat ctctataagg gctatatttt acaggatcgc tacaagtacc agttagagaa
    51361 tcgtcatcca tatttactga tggaacatga ttttaaagag acagcagagg agatttttca
    51421 tgctctacct acttttcaac aggggacaga tttagataag aagattctct gggaatggct
    51481 ccagttaatc gaatatatgg ctgaaaacgg tggccagcat atgcggattg gtctggattt
    51541 gacatctggt tttcttgtct tttcaaggat ggcagccatt ttgaaacggt atttggaata
    51601 caatcgtttt attaccattg aagcttatga ccctagtcgg cattatgatt tgctggttac
    51661 caataacccg attcataaga aggaacagac accagtctat tatttaaaaa atgacttgga
    51721 tatggaggat ttggtagcga ttcgccagtt attattcact taaaaggctt ggttaatcca
    51781 ggtctttttt gtgaaattca cacaatctcc tcacattttt ttaaaaatta aaaaaagttg
    51841 ataaacaaga aagcgcttta ttttgtatac tagtaagtgt aaagaggaaa cacctcaaga
    51901 tctttatcag gaggacagta catgtcacaa gaaaaataca tcatggccat tgaccaggga
    51961 actacaagtt ctcgtgccat cattttcaac aaaaaagggg aaaaggttag ctcgagtcaa
    52021 aaagagttta cccagatttt ccctcaggca ggttgggttg agcacaatgc caatgaaatt
    52081 tggaactctg ttcagtcagt tattgcgggt gctttcatcg aaagtggtgt caagccaaat
    52141 caaatcgagg caatcgggat taccaaccaa cgtgaaacaa cggttgtctg ggataagaaa
    52201 acaggacttc ctatctacaa tgctatcgtt tggcagtcac gccagacagc acctttggct
    52261 gagcaactaa aaagccaagg ttatgtggaa aaattccatg aaaagactgg tttgattatt
    52321 gatgcttact tctctgctac caaggttcgt tggattttgg atcatgtaga aggtgctcaa
    52381 gagcgagcag aaaaagggga attgctcttt ggtactatcg atacttggtt ggtttggaaa
    52441 ttgactgacg gtgcggctca cgtgactgac tactcaaatg cagctcgtac catgctttat
    52501 aacattaaag aactcaaatg ggatgatgag attttggaaa tccttaacat tccgaaggct
    52561 atacttccag aagttcgttc taactccgaa atctacggca agacagctcc attccatttc
    52621 tacggtggag aggtgccaat ctcaggtatg gctggggacc aacaagcagc cctctttgga
    52681 cagttggctt ttgagccagg tatggttaag aatacttatg gaacaggctc tttcatcatc
    52741 atgaatactg gggaagagat gcagttgtct gaaaacaacc tcttgacaac cattggttac
    52801 ggaatcaacg gtaaggttta ttatgccttg gaaggttcta tcttcatcgc aggaagtgct
    52861 attcagtggc ttcgtgacgg tcttcgcatg gttgaaaatt caccagaatc tgaaaaatac
    52921 gctcgtgatt ctcacaacaa cgatgaagtt tatgtcgttc cagcctttac aggtctaggc
    52981 gctccatact ggaaccaaaa tgctcgtggt tccgtctttg gtttgactcg tggaacaagc
    53041 aaagaagact ttatcaaggc gactttgcaa tctattgctt atcaagtgcg tgatatcatc
    53101 gacaccatgc aagtggatac tcagaccgcc attcaagtac tgaaggtgga tggtggtgca
    53161 gccatgaaca acttcctcat gcagttccag gcggatattt taggcattga cattgcacgt
    53221 gctaaaaacc tggaaacaac agctctagga gcggccttcc tagcaggttt gtcagtaggg
    53281 tactggaaag acttggacga gttgaaactc ttgaacgaga caggagaact ctttgagcca
    53341 tctatgaacg aatctcgcaa ggaacaactc tacaagggct ggaagaaggc tgtgaaagca
    53401 actcaagtct ttgcggaagt agacgactaa tactggcaga ataaagcgat ttatttagaa
    53461 agtgtgtaaa tatggaattt tcaaagaaaa cacgtgaatt gtcaattaaa aaaatgcagg
    53521 aacgtaccct ggacctcttg attatcggtg gaggaatcac aggagctggt gtagccttgc
    53581 aggcggcagc tagcggtctt gagactggtt tgattgaaat gcaagacttt gcagaaggaa
    53641 catctagtcg ttcaacaaaa ttggttcacg gaggacttcg ttacctcaaa caatttgacg
    53701 tagaagtggt ctcagatacg gtttctgaac gtgcagtggt tcaacaaatc gctccacaca
    53761 ttccaaaatc agatccaatg ctcttaccag tttacgatga agatggagca acctttagcc
    53821 tcttccgtct taaagtagcc atggacttgt acgacctttt agcaggtgtg agcaacacgt
    53881 cagctgcgaa caaggttttg agcaaggatc aagtcttgga acgccagcca aacttgaaga
    53941 aggaaggctt ggtaggaggt ggagtgtatc ttgacttccg taacaacgat gcgcgtctcg
    54001 tgattgaaaa catcaaacgt gccaaccaag acggtgccct cattgccaac cacgtgaagg
    54061 cagaaggctt cctctttgac gaaagtggca agattacagg tgttgtagct cgtgatctct
    54121 tgacagacca agtatttgaa atcaaggccc gtctggttat taatacaaca ggtccttgga
    54181 gtgataaagt acgtaatttg tctaataagg gaacgcaatt ctcacaaatg cgcccaacta
    54241 agggagttca cttggtagtg gattcaagca aaatcaaggt ttcacagcca gtttacttcg
    54301 acacaggttt gggtgacggt cgtatggtct ttgttctccc acgtgaaaac aagacttact
    54361 ttggtacaac tgatacagac tacacaggtg atttggagca tccaaaagta actcaagaag
    54421 atgtagatta tctacttggc attgtcaaca accgctttcc agaatccaac atcaccattg
    54481 atgatatcga aagcagctgg gcaggtcttc gtccattgat tgcagggaac agtgcctctg
    54541 actataatgg tggaaataac ggtaccatca gtgatgaaag ctttgacaac ttgattgcga
    54601 ctgttgaatc ttatctctcc aaagaaaaaa cacgtgaaga tgttgagtct gctgtcagca
    54661 agcttgaaag tagcacatct gagaaatatt tggatccatc tgcagtttct cgtgggtcta
    54721 gcttggaccg tgatgacaat ggtcttttga ctcttgctgg cggtaaaatc acagactacc
    54781 gtaagatggc tgaaggagct atggagcgcg tggttgacat cctcaaagca gaatttgacc
    54841 gtagctttaa attgatcaat tctaaaactt accctgtttc aggtggagaa ttgaacccag
    54901 caaatgtgga ttcagaaatc gaagcctttg cgcaacttgg agtatcacgt ggtttggata
    54961 gcaaggaagc tcactatctg gcaaatcttt acggttcaaa tgcaccgaaa gtctttgcac
    55021 ttgctcacag cttggaacaa gcgccaggac tcagcttggc agataccttg tcccttcact
    55081 atgcaatgcg caacgagttg gctcttagcc cagttgactt ccttcttcgt cgtaccaacc
    55141 atatgctctt tatgcgtgat agcttggata gcatcgttga gccagttttg gatgaaatgg
    55201 gacgattcta tgactggaca gaagaagaaa aagcaactta ccgtgctgat gtcgaagcag
    55261 ctctcgctaa caacgattta gcagaattaa aaaattaaga aaaaataaaa gaggtggagg
    55321 gcagcattcc ttgtcgcccg tcccttcttt ttaatggaga cagaaagatg atgaatgaat
    55381 tatttggaga atttctaggg actttaatcc tgattcttct aggaaatggt gttgttgcag
    55441 gtgtggttct tcctaaaacc aagagcaata gctcaggttg gattgtgatt actatgggtt
    55501 gggggattgc agttgcggtt gcagtctttg tatctggcaa gctcagtcca gctcatttaa
    55561 atccagctgt gacagttggt gtagctttaa aaggtgactt gccttgggct tccgttttgc
    55621 cttatatctt agcccagttc gcaggggcca tgctgggtca gattttggtt tggttgcaat
    55681 tcaaacctca ctatgaggca gaagaaaatg caggcaatat cctggcaacc ttcagtactg
    55741 gaccagccat caaggatact gtatcaaact tgattagcga aatccttgga acctttgttt
    55801 tggtgttgac aatctttgct ttgggtcttt acgattttca ggcaggtatc ggaacctttg
    55861 cagtgggaac tttgattgtc ggtatcggtc tatcactagg tgggacaaca ggttatgcct
    55921 tgaacccagc tcgtgacctt ggacctcgta tcatgcacag catcttgcca attccaaaca
    55981 agggagacgg agactggtct tacgcttgga ttcctgttgt aggccctgtt atcggagcag
    56041 ccttggcagt gcttgtattc tcacttttct agtttatact cttcgaaaat caaattcaaa
    56101 ccacgtcagc gtcgccttac cgtactcaag tacagcttgc ggctagcttc ctagtttgct
    56161 ctttgatttt cattgagtat tagaaaacaa ttatgttgat agagcttggg caagagccca
    56221 atttcagcaa aaaatgaagt aaatcttctc ataataaaac gcatcatatc aagcacgaaa
    56281 attccacgag gtcaactaca gtcagaaagc tgaacaacaa gccaaaacgc ccaaaaaagg
    56341 cggcaaaaag caagcacctg caagcaacgt gccgaaatgg tcaaatcctg attatgtcaa
    56401 cgaattagac ccaaaaatcg ttgatatgct agtagaattt cacaagtcac aaggcacttt
    56461 ggaaactccc gaggcgcaag cagaaatcgc ccaaaaacgt gaagaaatcg agcaaaggag
    56521 agctgagctt gagggtaaaa aacaagagct tttgaaccgc ttgaacaaat agagtttcgc
    56581 aagtattatg cttacaaatt acttgagcaa ttaactaaaa tataaactct gcctagatat
    56641 aaaggcaggg tttatatttt agaaattcac gtaggttgtt acggttttta catacccagt
    56701 atagtttgag tttctatagt attcagtgat aaacttccat tttctttgag caacatggat
    56761 ataagtactt gttatgtagt atggatatgg gctttgtgaa tccaagtaag actgataagc
    56821 ttgtatacca aaatatgctc caccaattat tgcaccccat ggacccccca ataaagcacc
    56881 tatcctacca atcatataac tgattccagc accagtcatg aagttagcga atgtgttagc
    56941 ttgtttattc ccatgtattg tgttgacgta attccaaaca ttaggatcgt atgatctaaa
    57001 agatatattt aggtcgattt cattcttttg ataagccata taaaatgccc cattgatata
    57061 gacgccgtca gcacgtcgtt caatagtgtc tacacttcca tctggattga caacctcaag
    57121 aacttcatcg cttaaaatat ttacttgcgt atctccgaac cgcactgatg agccattctc
    57181 aaactgagcc tcaccagata caactttaga gtttgccgat aagctatcat cagcaaaaac
    57241 aacaagcgac ggggaaatgc tagacataca gaaaacagac ataactagca aacacatgca
    57301 tttaaacatc ttagacataa cggaaactct tttgtatttt tgattttttt caacttttat
    57361 tatacaataa aaccaaataa aaagaaagcg gtaacaatat gcttaatgcg aaaatttttt
    57421 atatattttt atgtttgatc gttatcgaaa ctacaggctt gttgttgttg aaaagaggtc
    57481 tcgaaatggg ttatttagac acagaagcta ttatcctcgc agttttttca tttgcttttt
    57541 acaacctatg ttcattcgct tgggtctgct ctacaataaa aaacaataaa aaataaa
//
LOCUS       DAVKUR010000006        56923 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKUR010000006 DAVKUR010000000
VERSION     DAVKUR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.006"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(99..632)
                     /gene="queF"
                     /locus_tag="VW749_000442"
     CDS             complement(99..632)
                     /gene="queF"
                     /locus_tag="VW749_000442"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0174538.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VW749_000443"
     CDS             complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VW749_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0174539.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(1270..1491)
                     /locus_tag="VW749_000444"
     CDS             complement(1270..1491)
                     /locus_tag="VW749_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0174540.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(1590..1970)
                     /locus_tag="VW749_000445"
     CDS             complement(1590..1970)
                     /locus_tag="VW749_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0174541.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(2115..3068)
                     /locus_tag="VW749_000446"
     CDS             complement(2115..3068)
                     /locus_tag="VW749_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0174542.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VW749_000447"
                     /pseudo
     CDS             complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VW749_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            4483..5043
                     /locus_tag="VW749_000448"
     CDS             4483..5043
                     /locus_tag="VW749_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0174543.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            5100..6008
                     /locus_tag="VW749_000449"
     CDS             5100..6008
                     /locus_tag="VW749_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0174544.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5960..6550
                     /locus_tag="VW749_000450"
     CDS             5960..6550
                     /locus_tag="VW749_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0174545.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            6553..7659
                     /gene="yqeH"
                     /locus_tag="VW749_000451"
     CDS             6553..7659
                     /gene="yqeH"
                     /locus_tag="VW749_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0174546.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7873..8184
                     /gene="yhbY"
                     /locus_tag="VW749_000452"
     CDS             7873..8184
                     /gene="yhbY"
                     /locus_tag="VW749_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0174547.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            8236..8865
                     /locus_tag="VW749_000453"
     CDS             8236..8865
                     /locus_tag="VW749_000453"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0174548.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVEYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8865..9458
                     /gene="yqeK"
                     /locus_tag="VW749_000454"
     CDS             8865..9458
                     /gene="yqeK"
                     /locus_tag="VW749_000454"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0174549.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            9459..9959
                     /locus_tag="VW749_000455"
     CDS             9459..9959
                     /locus_tag="VW749_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0174550.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            9972..10325
                     /gene="rsfS"
                     /locus_tag="VW749_000456"
     CDS             9972..10325
                     /gene="rsfS"
                     /locus_tag="VW749_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0174551.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            10428..11174
                     /locus_tag="VW749_000457"
     CDS             10428..11174
                     /locus_tag="VW749_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0174552.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            11184..12281
                     /locus_tag="VW749_000458"
     CDS             11184..12281
                     /locus_tag="VW749_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0174553.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTARSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            12519..12773
                     /locus_tag="VW749_000459"
     CDS             12519..12773
                     /locus_tag="VW749_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0174554.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            12777..13031
                     /locus_tag="VW749_000460"
     CDS             12777..13031
                     /locus_tag="VW749_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV0174555.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            13222..14835
                     /locus_tag="VW749_000461"
     CDS             13222..14835
                     /locus_tag="VW749_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0174556.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            14965..15591
                     /gene="gmk"
                     /locus_tag="VW749_000462"
     CDS             14965..15591
                     /gene="gmk"
                     /locus_tag="VW749_000462"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0174557.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            15616..15930
                     /locus_tag="VW749_000463"
     CDS             15616..15930
                     /locus_tag="VW749_000463"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0174558.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            15996..18392
                     /locus_tag="VW749_000464"
     CDS             15996..18392
                     /locus_tag="VW749_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0174559.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQVRILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTRNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            18405..19340
                     /locus_tag="VW749_000465"
     CDS             18405..19340
                     /locus_tag="VW749_000465"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0174560.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPNRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            19333..20646
                     /gene="rsmB"
                     /locus_tag="VW749_000466"
     CDS             19333..20646
                     /gene="rsmB"
                     /locus_tag="VW749_000466"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0174561.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            20661..21401
                     /locus_tag="VW749_000467"
     CDS             20661..21401
                     /locus_tag="VW749_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0174562.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            21398..23377
                     /gene="pknB"
                     /locus_tag="VW749_000468"
     CDS             21398..23377
                     /gene="pknB"
                     /locus_tag="VW749_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0174563.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            23492..24250
                     /locus_tag="VW749_000469"
     CDS             23492..24250
                     /locus_tag="VW749_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0174564.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            24252..24701
                     /locus_tag="VW749_000470"
     CDS             24252..24701
                     /locus_tag="VW749_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0174565.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            24763..25389
                     /locus_tag="VW749_000471"
                     /pseudo
     CDS             24763..25389
                     /locus_tag="VW749_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            25457..25705
                     /locus_tag="VW749_000472"
     CDS             25457..25705
                     /locus_tag="VW749_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174566.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            25836..27008
                     /locus_tag="VW749_000473"
     CDS             25836..27008
                     /locus_tag="VW749_000473"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0174567.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            27008..28282
                     /locus_tag="VW749_000474"
     CDS             27008..28282
                     /locus_tag="VW749_000474"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0174568.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQDDPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(28318..29283)
                     /locus_tag="VW749_000475"
     CDS             complement(28318..29283)
                     /locus_tag="VW749_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0174569.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVTTTGYFLPVTLLPGKSI"
     gene            complement(29264..30718)
                     /locus_tag="VW749_000476"
     CDS             complement(29264..30718)
                     /locus_tag="VW749_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0174570.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31094..32977
                     /locus_tag="VW749_000477"
     CDS             31094..32977
                     /locus_tag="VW749_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0174571.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            33126..34013
                     /locus_tag="VW749_000478"
     CDS             33126..34013
                     /locus_tag="VW749_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0174572.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(34056..34673)
                     /locus_tag="VW749_000479"
     CDS             complement(34056..34673)
                     /locus_tag="VW749_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0174573.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(35088..35276)
                     /locus_tag="VW749_000480"
                     /pseudo
     CDS             complement(35088..35276)
                     /locus_tag="VW749_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(35786..35866)
                     /locus_tag="VW749_000481"
                     /pseudo
     CDS             complement(35786..35866)
                     /locus_tag="VW749_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            35982..36875
                     /locus_tag="VW749_000482"
     CDS             35982..36875
                     /locus_tag="VW749_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174574.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            36872..38071
                     /locus_tag="VW749_000483"
     CDS             36872..38071
                     /locus_tag="VW749_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174575.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(38424..39191)
                     /locus_tag="VW749_000484"
     CDS             complement(38424..39191)
                     /locus_tag="VW749_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174576.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(39208..39903)
                     /locus_tag="VW749_000485"
     CDS             complement(39208..39903)
                     /locus_tag="VW749_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174577.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(39908..40273)
                     /locus_tag="VW749_000486"
     CDS             complement(39908..40273)
                     /locus_tag="VW749_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0174578.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            40413..40886
                     /gene="nrdR"
                     /locus_tag="VW749_000487"
     CDS             40413..40886
                     /gene="nrdR"
                     /locus_tag="VW749_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0174579.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            40887..42056
                     /locus_tag="VW749_000488"
     CDS             40887..42056
                     /locus_tag="VW749_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0174580.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            42057..42953
                     /gene="dnaI"
                     /locus_tag="VW749_000489"
     CDS             42057..42953
                     /gene="dnaI"
                     /locus_tag="VW749_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0174581.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            42950..43663
                     /locus_tag="VW749_000490"
     CDS             42950..43663
                     /locus_tag="VW749_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0174582.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAKMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            43677..44987
                     /gene="der"
                     /locus_tag="VW749_000491"
     CDS             43677..44987
                     /gene="der"
                     /locus_tag="VW749_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0174583.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            45078..45413
                     /locus_tag="VW749_000492"
     CDS             45078..45413
                     /locus_tag="VW749_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174584.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            45553..45888
                     /locus_tag="VW749_000493"
     CDS             45553..45888
                     /locus_tag="VW749_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174585.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            46073..46864
                     /locus_tag="VW749_000494"
     CDS             46073..46864
                     /locus_tag="VW749_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174586.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILHVVPYMVLKKYEDNV"
     gene            46857..47498
                     /locus_tag="VW749_000495"
     CDS             46857..47498
                     /locus_tag="VW749_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174587.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            47502..48152
                     /locus_tag="VW749_000496"
     CDS             47502..48152
                     /locus_tag="VW749_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0174588.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            48163..48450
                     /locus_tag="VW749_000497"
     CDS             48163..48450
                     /locus_tag="VW749_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174589.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            48596..51109
                     /gene="secA"
                     /locus_tag="VW749_000498"
     CDS             48596..51109
                     /gene="secA"
                     /locus_tag="VW749_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0174590.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            51190..52221
                     /locus_tag="VW749_000499"
     CDS             51190..52221
                     /locus_tag="VW749_000499"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0174591.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            52223..53254
                     /locus_tag="VW749_000500"
     CDS             52223..53254
                     /locus_tag="VW749_000500"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0174592.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            53293..53661
                     /locus_tag="VW749_000501"
     CDS             53293..53661
                     /locus_tag="VW749_000501"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0174593.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            53651..54754
                     /locus_tag="VW749_000502"
     CDS             53651..54754
                     /locus_tag="VW749_000502"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0174594.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            54773..56788
                     /gene="recG"
                     /locus_tag="VW749_000503"
     CDS             54773..56788
                     /gene="recG"
                     /locus_tag="VW749_000503"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0174595.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
BASE COUNT        16827 a        10959 c        12989 g        16148 t
ORIGIN      
        1 agctgacttc gtcagtttta tctacaacct caaacactgc tttgagtaac ctgcggctaa
       61 cttcctagtt tgctctttga ttttcattga gtatgacttt agcggttgtc aattttctct
      121 ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc cctcatactt agttccttgc
      181 ttaccgtagt tatagtaggg gtcgattgaa atgccaccgc gcggagtgaa ttttccccag
      241 acttctaaat agcgagggtc tagcaagttg accaagtctt tcccgatggt gttgatacag
      301 ttttcgtgga aatctccgtg gtttcggtag ctaaatagat atagtttgag ggattttgac
      361 tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg tcgcaaagtc tggctgagca
      421 gtgatttgtc ccagcagaga catatcgagg atatggtgac gaatgccctg ttccttagcg
      481 atttctctag taatttgaat ttcgaggtga tgacgttggc cgtaggcaaa ggtgacagct
      541 tcgactgttt catagtgttg catggtccag aaaaggcagg tttttgaatc ttgaccacca
      601 ctaaagacga ccaaggctga ttgacgtttc atagtactcc ttccaaaatg ggaaatgttc
      661 agagcacgta aaaagctccc attagggagc taaaaaatac caaatcgagg ttttttttag
      721 cgatggcata tcccaaatat cgtaatattc tatttatata gtaaaatgaa ataagaacag
      781 gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agagatgtac
      841 tattctagtt tcaatctact atagtctagc atatcttttg aaaaatggca aagggcaaga
      901 aaaaagagac caaagaaagt acttggtctc tcgtttgatt agctcaattc agcaatgatg
      961 gccttgattt gttctgctgt gtgaacacct gcaacttgtt tgacaacttg gccgtctttt
     1021 ttgaagagaa gagttggaat agacatgatt ccaaaagcac gagctgtgtt tggattttca
     1081 tcaacgtcca ttttaacgat tttcaagaca tcttctgaaa gttcttcaga caatttgtcc
     1141 aagattggac cttgcatacg acatggacca caccaagttg cccagaagtc tactaagacc
     1201 aaaccgtctt ttgtttcttg ttcgaatgtt gcatctgtaa ttgcttttgc cattgtattt
     1261 ctcctttttt tagttatatt ggcttaaatc ttgtttcatg agatagaaga agatatctcc
     1321 ataagtccca tggtagtcca aattatgacc cttgtaagtt aatttttgga cagggtagta
     1381 gtctgcgacg ccgataaggc aagcttgttg cgaacgttca aagtcttcat aagactcgaa
     1441 agtcacagtt ctttcgttct tgctggcatc tatataggta atttcaatca tgtttaaaac
     1501 tcctttgttt aatgctaact ttattttact ccttataaaa gagaatgtca agaaaaatga
     1561 ttgcgcacgc aacttttttt aaaatcatct taaatcaaga aatccaaacc tgcttccaag
     1621 ctttcttcga cagtcttttg tagcgaggcc agtgtctttt gcccatcatt tgtcaggcag
     1681 ataaaactag agcgtctatc ttgatggcaa cacatgcgac tgagtagacc gcaattttta
     1741 gcttccaagc gagccaccat cctagaaact gcgctcgggc tcagatgaag cttatctggc
     1801 aggtcaatct ggcgtagaga tttttcttca gccaagtcca gatagtagag caggtagaac
     1861 tctttcaagg tcagactttg ctcgctctgt tgggcaatgg tctcttccaa gagactttca
     1921 atttctttct gacgccgatt gaagtcaaac catttttcca aataggtcat agtgtctcct
     1981 ttctttttag agtcataatt atagaagaaa gtccattaac gggcagtctt tgcgtcataa
     2041 gatgattgcg catgcaataa ttatactact tttcaagaat gctggcaagc tctgtttttt
     2101 agtggttttc ttttttactg tctatatttt tggtaaaaat caacttttac ttggatgaag
     2161 gttttggctt cacgtaggag ttgaagaaga gtggcgcggg tttcaaactc ttctcttgtc
     2221 ttgggcagac tgcggttccg gaagacttcc agataacgtt caatttcatc tagcaaatca
     2281 gaagcaggat tggtctggct cagttgacct gcaatttttg aaaagagttg cgctaagatc
     2341 aggctttcac tggcggcaag gtgacaagtg ttaatctgtt gggccatgtt tctcaggata
     2401 cgactttgtc gttgtctcat ctcaaagtag tggatatggt agtcggtctg gtgaaagagg
     2461 tggtcagagt gatccaaata gaccagtctg agggcttctt tcaaaagcgt gtctaattct
     2521 gctaccagct gtgctcggtt gcgtccgtct cctctggata aatagtattt gaagcgctgg
     2581 aggatatctt ttaacttttc ttccaccagc gtgtggtagt gctggatttc ctcttctcgt
     2641 gaaggcatat agagattaac aagcaaggca aatcctgtac caatagcaaa gagaaggaat
     2701 tcgttgacta ggaggtctgg agaggttgac tcttgaacca agagatggct aaccaaaacc
     2761 gtgcttggtg tgatgccaat ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc
     2821 agatagaggc cgagactcca gatatgaaat ccgctcaagt gaaaagctag aacgccgata
     2881 gccagagcta gaagcataga aaaaagacga ttgcgagcca gttttaaagt acttctacgc
     2941 gtatcagata ggctcaagag agcgataatt ccagccgaaa ctgctgacga aagattgaga
     3001 aaataagcaa gcaggcaggc aagacaggta gctaagatga gcttggtcgt acgttggcta
     3061 atagacataa gaatttccta ataagttaga ataaaagcgt aaaagacaag acatgagcag
     3121 gcttgccttg atgagttatt ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag
     3181 gacatctgta gaagagttaa gggctgtttc acatgagtct tggatgacac caatcacaaa
     3241 accaacccca acaatttgta tggcaatatc gttagaaata ccgaaaaggc tacaagcaac
     3301 tgggataaga aggagggaac ctccggcaat acctgaagca tcacaggctg agatagctgc
     3361 taccacactg aggacaaagg ctgtggcaaa gtcaacagga attccaagag tgttaactgt
     3421 aacaagggtc aaaacgttaa tggtaatcgc tactccagcc atattgatag tagaaccgag
     3481 tgggatagaa acagaatagg tatctgggtt gagtccaagg tcatggcaga gtttcatgtt
     3541 gacaggaatg ttagtcgcag aactacgagt gaaaaaggct gtcacaccgc tgacacggag
     3601 gcagttccaa actagagggt aaggattgcg tctcataaag aagaaggcaa tcaaagggtt
     3661 gaccacaggg gcaacaaaaa gcatagtcgt tactaataga accaataaaa taccgtagtt
     3721 ggcaaggctt ccgactccct tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa
     3781 tggagccaga ttgatgatcc attcgacaat tttagaagtc acgtcagcga tagtttttag
     3841 caattcttta ctatttttac tggcttctct catagcgatt ccaaaaatga ctgcccaaga
     3901 taagattcta atatagttag cagtaagcag ggcgttgact gggttgtcaa ccagtttgag
     3961 caagaggttg ctgaggacct gcccaatccc atctggtggt gcaatttcag tattggcact
     4021 atttagggta atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc
     4081 gaaagtccct atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc
     4141 ttttgatgtt ggaaagggca ttggcaacga gggcaaagac taggatagga gcaacagctt
     4201 ttagacctcc aacgaataaa tccccgagta gcccaatccc tgagagatta ggaagggtca
     4261 gtcctaggat tccccacaaa gcataccaat caagatacgc ttgacaaggc ttgccttatt
     4321 ccaagcatga atgattcttt tcataataat ctcctttttg tgtagtgatt atgattatag
     4381 tataaatgat agacaaaatc aagaattttc tgtctatttt ttgaatattt atggagaatg
     4441 agactgatga aaatatggta taatgaaata aaggagtttt atatgcaaaa atttattcag
     4501 gcttatattg aaaagctaga tgtgacaacc attatcgaga atattctaac caaggtcatt
     4561 tctcttttac tgcttttgat tgtattttat attgctaaaa aaatgcttca taccatggtg
     4621 cagagaattg tcaaaccttc tctaaaaatg tctcgtcatg atgtcggacg ccaaaaaacc
     4681 atctcacgtt tactagaaaa tgtgtttaat tatacgctat atttcttttt actctactgc
     4741 attttgtcga ttttaggttt gccagtttct agtttgctgg ctggagctgg tattgctggg
     4801 gtagcgattg gtatgggagc ccaaggcttt ctgtctgatg tcatcaatgg ctttttcatc
     4861 ctctttgaac gtcaactgga tgtgggagat gaggtcgttc tgacaaatgg accgattact
     4921 gtatcgggta aggttgtcag tgtgggaatt cgtacgacac agcttcgtag cgaggagcaa
     4981 gcccttcact ttgtccctaa ccgaaatatc acagttgtta gcaatttctc acgcacagac
     5041 tagacctgtt attttaagta atttgtggta caatagaggg agtttaataa ggagaaaaga
     5101 tggttttaga aaagcagttg ggcaatggtt gtacctggat agacctagac ctaggaaagt
     5161 tgaataaact agaagacctt tctgaaattt acggtttgga caaggaaacc attgaatacg
     5221 cactggatag aaacgagcgc gcccacatgg attaccaccg tgaaagtggg acggttacct
     5281 ttatctataa tgtcctagac gtaaaaaagg acaaggccta ctatgagact tttcccatga
     5341 cctttattgt cgagcatcgt cgcctgatta ccattagtaa taccaagaac gcctatgtca
     5401 ttgaacagat gactcgttat ctggagagcc atgacacgct ttcgatttat aagtttctct
     5461 ttgccagtct ggaaattatc agcaatgcct actatcctgt cattgagcag atggacaaga
     5521 gtagggatga ggtcaatgac ctcttgcgcc agcgaactac caagaaaaac ctctttgccc
     5581 tgtctgattt ggagactggt atggtttatc tgacggcagc tgccaaacaa aatcggattt
     5641 tgttagagca tattcaaggt catgccttgt atcgtagttt tgatgagatt gagagagaac
     5701 agtttgatga tgccatgatt gaggctcatc agctggtatc catgacagac ctaatctctc
     5761 agattttaca gcagctttca gcctcttaca acaatattct aaacaataat ctgaatgaca
     5821 atttgacaac cttgactatc atttcagtct tgctagctgt tttggcagtc gtgacaggct
     5881 ttttcggaat gaatgttccc ttacctttaa cagatgagcc ccatgcttgg ctctatatca
     5941 gtttggctag tgcaggtttg tggattgttt tatccttgtt actaaggaaa attgcgaaaa
     6001 aaagttaaga aaaggagcca gaatggcgat tgaaaattat ataccagatt ttgctgtgga
     6061 agcagtctat gatctgacag tcccaagcct gcaggcgcag ggaatcaagg ctgttttggt
     6121 cgatttggat aataccctca ttgcttggaa caaccctgat ggaacgccag agatgaagca
     6181 atggctacat gaccttcggg acgcgggtat tggcattatc gtagtgtcaa ataacaccaa
     6241 aaaacgcgtt caacgagcag ttgagaaatt tgggattgat tacgtttact gggccttgaa
     6301 gcccttcaca tttggtattg accgtgctat gaaggaattc cactatgaca aaaaggaagt
     6361 ggtcatggtt ggcgaccagc tcatgacaga tatacgagca gcccaccgtg cagggattcg
     6421 gtcaatttta gtcaaaccct tggtccaaca tgactcaatc aaaacgcaga ttaaccgaac
     6481 tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac ggaccgatta catataaaaa
     6541 aggaatttaa ctatggaaga aattctctgt attggttgtg gagcaaccat tcagacgaca
     6601 gataaagctg gtcttggttt taccccccag tcggcacttg aaaaaggttt ggagactggc
     6661 gaagtctatt gccaacgctg tttccgtctc cgccactaca atgaaatcac agatgtccag
     6721 ttgacgaacg atgatttcct caagctcttg cacgaggtgg gagacagtga tgccttagtg
     6781 gtcaatgtca ttgatatctt tgattttaat ggatctgtca tcccaggttt accacgtttc
     6841 gtctcgggca atgatgtcct cttggtagga aataaaaaag atatccttcc taagtcagtt
     6901 aagtctggta agattagcca gtggctcatg aaacgtgccc atgaagaagg tcttcgtcca
     6961 gtcgatgtgg tcctaacttc agcacaaaat aaacatgcca ttaaggaagt cattgacaag
     7021 attgaacact accgtaaggg ccgcgatgtc tatgtggtcg gtgtgaccaa cgttggaaaa
     7081 tcaactctaa tcaatgctat tatccaagaa atcacgggtg atcagaatgt catcactact
     7141 tcacgcttcc caggtacaac cttggacaaa atagagattc cgcttgacga cggatcttat
     7201 atttacgata cgccgggaat tatccaccgc caccagatgg ctcactactt gacggccaaa
     7261 aacctcaagt atgtcagtcc taaaaaggaa atcaagccta agacctatca gcttaatcct
     7321 gagcaaaccc tatttttagg tggtttggga cgctttgact ttatagcagg agaaaagcaa
     7381 ggatttactg ctttctttga taatgaactc aaactccatc gtagcaagct tgaaggagct
     7441 agtgctttct acgataagca cctgggaact cttctgacac caccaaatag caaggaaaaa
     7501 gaagatttcc caaggctagt ccagcatgtc tttaccatta aagataagac agacctagtc
     7561 atctcaggcc taggctggat tcgtgtaaca ggcatagcaa aagtcgccgt ctgggcacca
     7621 gaaggcgtcg ccgtcgtcac acgaaaagca attatttaaa acaaaatcgc tgagcgaaca
     7681 aagtgagctc atatagcgat agttattgcc gtggtgtgat tgccaatctg tagattggca
     7741 aggggcacaa ttgagaccaa ggctcaattg tgaggtcagg aaatccattt ttcaaagatg
     7801 aaatctttgg aaaattagtt ccgaccgtcc ctcaccacct aaaataacta tccaaaaaca
     7861 aggaagaaaa ttatgtcatt aacatcaaaa caacgtgcct tcctcaacag ccaggcacac
     7921 accctcaaac ctatcatcca aatcgggaaa aatggactca acgaccaaat caaaaccagc
     7981 gtccgtcaag ctcttgatgc gcgtgaatta atcaaggtta ctctcttaca aaacacagat
     8041 gaaaacatcc acgaagtagc tgaaattttg gaagaagaaa tcggtgtgga tacagtccaa
     8101 aaaataggac gcatcttgat tttgtttaaa caatctagca agaaagaaaa tcgcaagatt
     8161 tctaagaaag tcaaagaaat ctaagaccga aactccaaat aactgttttt atagagaaat
     8221 aaaggggact agcctatgac aatcgaacta ttgactccct ttaccaaggt agagttggag
     8281 ccagaaatca aggagaaaaa acgcaaacaa gttgggattt taggggggaa ttttaaccct
     8341 gttcacaatg cccatctcat tgttgcggat caagtacggc aacagttggg actggatcaa
     8401 gttcttctca tgcctgaata ccaacctcct cacgttgata aaaaggaaac catccctgaa
     8461 caccatcgtc tcaagatgct tgagttggca attgagggaa ttgacggcct agtcattgaa
     8521 accattgagt tggagcgcaa gggtatttcc tacacctacg acaccatgaa gattttgaca
     8581 gagaagaatc cagatacgga ttattacttt atcatcggtg ccgacatggt tgagtatctg
     8641 cctaagtggt accgaattga tgaactggtt gacatggttc agtttgtggg ggttcagcgt
     8701 ccacgctaca aggtagggac ttcctatcca gttatctggg tggacgtacc gctcatggat
     8761 atctcgtcca gcatggtgcg ggacttcctt gcccaaggtc ggaaacccaa ctttctccta
     8821 cctcagccag tgctagacta catcgagaag gaggggctct actgatgtcc tatcaagact
     8881 atatcaactg ctcccgtgag gccttgttgg aaaaaatggc agagcttcta cctgagaaac
     8941 gtctaaccca ttgtctaggt gtggagcgtg ccgctatgga attagctcag cgctttggtg
     9001 tagatgttgg gaaagcaagt ctagcaggtc ttcttcatga ctatgctaaa aagttgtcaa
     9061 atcaggaatt tctagccttg attgaccgtt accagctaga ccctgacctc aaaaactggg
     9121 gcaataatgt ctggcatggt atggtcggaa tttacaaaat tcaggaagat ttggatttgc
     9181 atgattctga aattctgcga gccattgaaa ttcatacagt cggagctggt caaatgacag
     9241 acctagataa ggtcatctac gtcgcagact atatcgagca caatcgagcc tttcctggag
     9301 tagatgtggc gcgtgagatt gcaagtctat cgctcaataa ggcggtggcc tacgaaacag
     9361 ctcgtaccgt ggagtatcta gctcatcagg gattccccat ctatccccaa acccttgaaa
     9421 cctataacgc ctttgtgcac tatttgaaag aggactaaat gaagacggct tttataatca
     9481 ttgatgttca gaatgtttta gtagaaactg ggttccagac aaaaagtcta ttggaaaaaa
     9541 tttcttattt acaaaaccag gctagaagca agaatattga aattatctat gttcaacata
     9601 ttgagaattc tgaagctcaa acatcagaag attggcagtt atctgcgctt ttaaatcgaa
     9661 aacctgctga aaaggtcttt cagaagaagt ataacagtat tttcaaagaa actggcttaa
     9721 aagaatactt ggataaacag gggattgaaa aattagtttt atgtggtatg cagacagaat
     9781 attgtgtgga tacctctgtc aaggttgcct ttgaatatgg ctatcagctt attgttccag
     9841 aaggtgctgt cacaaccttt gatggggatg acattccagc agaaacgatt aatgaatttt
     9901 atgaggacat ttgggaggag cactttgcag atgtcctaga ttacaaacat attttctaaa
     9961 aagaggatta aatgaacgaa aaagaattac tagaactagt cgtgaaagcg gctgatgaga
    10021 aacgtgcgga ggatatcctc gcacttgatg tacaagattt gactagtgtg acggactact
    10081 ttgtcatcac tagctcaatg aatagccgtc agttggacgc tatcgcagct aatatccgtg
    10141 aaaaagtagc tcaagcgggc tttaaaggta gccatgtcga aggcgatgca gctggaggct
    10201 gggtcttact ggacctcggt gctgttgtcg tgcatatctt ttcagaagaa atgcgtgccc
    10261 attataatct agagaagcta tggcatgagg cgaattcagt agatatttca gaagctcttg
    10321 cttagaagat gaactcagtt gtagtcaact gggtttcttt gcttatttta gaaaaattga
    10381 tagaaaggta aagggctagt ggtgtttacc atggagctct tagtatcatg attatggcga
    10441 cttatgaaac ctttgcggcg gtctatgatg cggtcatgga cgatagttta tacgacaaat
    10501 ggacgaattt ttctctgcgt catttgccta agaccaagga gaaaaagaaa ctcttggaac
    10561 tggcttgtgg gacaggaatt caatcagtgc gcttctctca ggctggtttt gatgtgactg
    10621 gacttgactt gagtgcggat atgttgaaga ttgcggagaa gagagcaact tcagccaagc
    10681 aaaagattgc ttttatagaa ggtaacatgc tgaatttgtc caaggcaggg aaatacgatt
    10741 ttgtcacgtg ttattcggac tctatctgct atatgcagga tgaggtggaa gtaggggacg
    10801 tctttaagga cgtgtacaat gcgctgaatg aagagggagt tttcatcttt gacgtgcact
    10861 cgacctacca gacagatgaa gtattccctg gctattccta ccatgaaaat gcggaagatt
    10921 ttgccatgct ttgggataca tatgaggacg aagctcctca ctccatcgtg catgagctga
    10981 ctttctttat caaggaggct gacggttcct ttagtcgcca cgatgaagta catgaggaga
    11041 ggacctatga gatcttgacc tatgatatct tactggaaca ggctggattc aagtccttca
    11101 aactctatgc agactttgag gataaggaac caacagaaac tagcacccgt tggttttttg
    11161 tggcgcagaa gtaggagatt agcatgacca tcacaggtat tatcgcggag ttcaatcctt
    11221 ttcataatgg ccataaatac ctgctggatc aggcagaggg actgaaaatt gttgccatgt
    11281 cagggaattt catgcagcgt ggagagcctg ctattgtgga taagtggaca agggcccaga
    11341 tggcgctgga aaatggcgca gacttggtag tggaattgcc ctttttagtc agtgttcagg
    11401 cagctgattt ctttggtcaa ggagctgtga atatcttgga tcgcttgggc attgatagtc
    11461 tagtttttgg gacagaggaa gttcgagatt atcagaaaat cgctgactta tacacagaga
    11521 aaggtgctga gatggagaaa tttgtggaaa atctgcctga ttccctttcc tatccccaga
    11581 aaacccaagc tatgtggaag gaatttgctg gtcttgattt ttcaggtaat acccccaatc
    11641 atgttcttgc tctggcctat gccaaggcgg ttgcaggacg aaatatcaag ctgcatccga
    11701 ttcagcgtca gggggcaggt taccattctg tgaataaaga tgtggacttt gcctcggcga
    11761 cagccctccg tcaacatcag aaggaccaag atttcttaga acgctttatg ccttctgttg
    11821 ccctatttga gcaggccagt aaggtgatct gggaagacta ttttcccttg ctccgctatc
    11881 aaatcttgtc aaatcccgac ctaaccacca tctatcaggt caatcaagaa atggctgtgc
    11941 gcattaaaga agctattaaa acagcccggt ctgtggaaga attggtcgag ttagtgacta
    12001 ccaaacgtta caccaaggcg cgtgtcagac gcctattgac ctatattttg atgcaggcta
    12061 gagaaaatgt cttgccagaa gtcattcatg tccttggatt tactgaaaaa ggtaggcaac
    12121 atctcaagtc tttgaaaggt caggtcagtc tagtcagccg aattggcaaa gaaccttggg
    12181 atgctatgac ccaaaaagca gaccagattt accaactagg aaatccaagt atagcagacc
    12241 agaattttgg aagagtgccg attagaatag aaacaaacta agtctaccga aaggtaggct
    12301 ttttgagatt ttttacgaat aatactcttc gaaaatcaaa ttcaaatcgc gtcaacgtcg
    12361 ccttgccgta ctcaagtaca gcctgcggct agtttcctag tttgctcttt gattttcatt
    12421 gagtataaat agatagaaaa gaaaatcttg tacaagttcc tgacaatttc tttcttttcg
    12481 tgtataatag tggaaaagag ctaaaacgag gtatggttat ggaagcagtc ctttactcaa
    12541 cattccgaaa tcatttaaag gactacatga agaaggtaaa tgatgaattt gagcctttga
    12601 cggtggtcaa taaaaatcca gatgaggaca ttgtagtcct ttcaaagagt gagtgggata
    12661 gtatccaaga aaccctgaga attgctcaaa ataaggaact ttctgataag gttttgcgag
    12721 gaatggctca agttcgtgct ggaagtactc aggtccatgt tattgaggag taagaaatgc
    12781 tgctcaagtt tacagaagat gcctgggcag attattgcta ctggcaaaat caggataaga
    12841 aaacgttaaa aagaatcaat aaactaatca aggatattca acgtgatccc tttacaggaa
    12901 taggtaaacc agaaccactc aaatatgatt accaaggagc ctggtcacgg cgtattgatg
    12961 cagaaaatcg cttgatttat atgatggatg gagatagcgt ggctttcttg tcctttaaag
    13021 atcattacta agtctattga aaggtaggct ttttctcaag tctctactaa actactattt
    13081 ctaaacaaca agtttatttt tgcaaatgtg ttccaaattc cccaaaacat attctatttt
    13141 aggtttgtga aaatcacttt tttatggtag aatgtaaaag aatgtatgtc attcggaata
    13201 acaataaaat gaggtaaaaa catggaaatc atgtcgcttg cgattgctgt ttttgccgtc
    13261 atcattggtt tagtcattgg atatgtcagc atctcagcta agatgaaatc atctcaggaa
    13321 gctgcagagt tgatgctttt aaatgctgaa caagaagcaa ctaatttacg tggacaagct
    13381 gagcgtgaag cggatttact tgttaatgaa gccaaacgtg aaagcaagtc tcttaaaaaa
    13441 gaagcactat tggaggccaa agaagaagcc agaaaatacc gtgaagaagt ggacgctgaa
    13501 ttcaaatcag aacgtcaaga actcaaacaa atcgaaagtc gtttgacaga gagagctact
    13561 agccttgacc gtaaggacga caatttgacg agtaaagaac aaacacttga acaaaaagaa
    13621 caaagtattt ctgatagagc gaaaaacctt gatgcgcgtg aagagcaatt agaggaagtc
    13681 gaaagacaaa aagaagcaga actagagcgt attggtgctc tgtctcaggc agaagcacga
    13741 gatattatct tggctcagac agaggaaaac ttgaccaggg agattgccag tcgcattcgc
    13801 gaagctgagc aagaggtcaa ggaacgttct gacaaaatgg ccaaggacat cttggttcaa
    13861 gctatgcaac gtatcgctgg tgaatatgta gcggagtcaa caaactcaac ggttcatctg
    13921 ccagacgata ctatgaaggg acgcattatt ggtcgtgaag gtcgtaacat tcgtaccttt
    13981 gaaagtttga caggggtcga tgtgattatc gacgatacac cagaagtggt gaccttgtca
    14041 ggatttgatc cgattcgtcg tgagattgcc cgtatgacta tggaaatgtt gctcaaagat
    14101 ggtcgtatac atccagctcg tatcgaagag ttggttgaga aaaaccgtca agagattgac
    14161 aataagattc gtgaatacgg tgaggctgct gcctatgaaa ttggtgcgcc aaaccttcat
    14221 ccagacttga tgaagattat gggacgtttg cagttccgta cttcatatgg acaaaatgtt
    14281 ttgcgccatt cgattgaggt tgctaagttg gctggtatca tggcgagcga acttggtgaa
    14341 aatgcggctc ttgcccgtcg tgctggattc cttcacgata tcgggaaagc cattgaccat
    14401 gaggttgaag gtagccacgt tgaaatcggt atggaattgg cccgtaagta caaggaaccc
    14461 ccagttgtgg tgaatacgat tgctagtcac cacggagatg ttgaagctga gagcgtgata
    14521 gcagttatcg tcgctgcagc agatgccttg agcgcagccc gtccaggtgc tcgtagtgag
    14581 tctcttgaaa gctacatcaa gcgtctccat gatttggaag aaattgctaa cggctttgaa
    14641 ggagtgcaaa ctagctttgc ccttcaagca ggacgtgaaa ttcgtatcat ggtcaatcca
    14701 ggaaaaatca aggacgacaa agtcacaatc ttggctcaca aagttcgtaa gaaaattgaa
    14761 aacaatctcg attatccagg aaatatcaag gtaaccgtga ttcgcgagct tcgtgcagta
    14821 gattatgcta aataaataag aaagagcagt tgaaaaatta ctgctttttt gttacactag
    14881 atagaaagac tgtaaaggat aatctggctt tttgccatta ttctagagaa atgttatttc
    14941 acagattgac taaaaggaga cacaatggca gaccgaggct tactaatcgt tttttctggt
    15001 ccttcagggg ttggaaaagg aacggttaga agagagattt ttgagagttc tgaaaaccaa
    15061 tttcaatact ctgtatcgat gacgacacgc gcacaacgtc ctggagaagt ggacggtgtc
    15121 gactatttct tccgtactcg tgaagaattt gaagagctga ttcgtcaagg acagatgttg
    15181 gaatacgcag aatatgtcgg taactactat ggaactcctc tgacctatgt caatgaaacc
    15241 ttggacaagg gaatcgatgt tttccttgaa attgaagttc agggtgctct tcaggtcaag
    15301 aaaaaggttc cagatgctgt ctttatcttc ctgacaccac cagatttgga tgaattgcaa
    15361 gatcgcttgg taggtcgtgg aacagatagt gcagaagtga ttgcccaacg aatcgaaaag
    15421 gccaaggaag aaattgccct catgcgtgag tatgattatg ccattgtcaa cgatcaggtg
    15481 cccctagctg ctgaacgtgt caaatgtgta attgaagcag aacacttctg tgtggatcgt
    15541 gtcattggtc actatcagga gatgttacca aaatctccaa ctacccgata aaatttagaa
    15601 aataggtaca agcaaatgat gttaaaaccc tctattgata ccttgctcga caaggttcct
    15661 tcaaaatatt cactcgtaat cttggaagca aaacgtgccc acgaattgga agcaggtgcc
    15721 ccagcaactc aaggtttcaa gtctgaaaaa tcaactcttc gcgctttaga agaaatcgaa
    15781 tcaggaaacg ttacaattca cccagatcca gaaggaaaac gcgaagcagt gcgtcgccgt
    15841 atcgaagaag aaaaacgccg caaagaagaa gaagaaaaga aaatcaaaga gcaaattgct
    15901 aaagaaaaag aagatggtga aaaaatttaa ggttgggggg actcaatctt attttttcta
    15961 ttgcaagaat gtactgacaa ggaggaggtg agaagatggc cctagctaag attatcgtag
    16021 atgtgccctt gatgcagacg gaccagccct atagttacag gattccggag gaatttgagg
    16081 gaatgctgga agttgggatg cgggttcatg tgccttttgg taagggtaat cgcctgattc
    16141 aagggattgt tcttggtttg gagtcccaat cagatggaga agagatggag caagatttaa
    16201 aagatattgc agaggtgctg gatttttctc ctgttctcac gccagaacaa ctctggctgg
    16261 ctgaggagtt acgcaaatct gtcttctcct acaaaatttc tatcctcaag gccatgcttc
    16321 caggatttct gaattctagc tatgacaaga ttctctatcc tctggaaggc ttgagtcagg
    16381 aagaacgagt gcgcctgttt ggttcagaag attcgctagc cttttcttca ctagaccttg
    16441 ccaagcaagc tgaaatgatg cgtttgacta gaaaaggcct gcttggtctg gaatatcagg
    16501 cagtcgatca aaagaaggtc aagacccagt cttggtatga ggttgaccat gctcaattag
    16561 aaggtgttga gatttctaca cgtgccaaga aaaagttgga actgagagat tatctgctgt
    16621 ctcatccaga gagcgcttcc ttggctagct tgttagagtc ctactcgcga gagcaagtca
    16681 acttctttgt ggatcaaggt gctgttacca tagtccaaaa ggaagttcaa cgctcggctg
    16741 cttattttga aggaattgaa gcaagtagac ctttggagtt aaatccagaa caaagacagg
    16801 cgcgtgatgc ggttgtgagt tctattggca gttctcaacc tccctttcta cttcaaggga
    16861 ttacaggaag tgggaagacc gaggtttact tgcagattat ccaaggtgcc ctggataagg
    16921 gcaagacagc tattttgctg gtacctgaga tttccttgac tcctcagatg accgagcgtt
    16981 ttatagcacg ttttggggac aaggtagcca ttcttcactc aggattatcc aatggtgaaa
    17041 agtatgatga atggcgcaag gtggagcgtg gcgatgccca agttgttgtt ggtgccagat
    17101 ctgctatctt tgctcctctg aaaaatctgg gtgtcatgat tattgatgaa gagcatgaag
    17161 cggcttataa gcaggacagc aatccccgtt accatgccag agaggtagct attttacggg
    17221 ctcagtataa tcaagcaact ctggtacttg gatctgcaac gccgagctta gagagccggg
    17281 cacgtgctgg caaaggcgtc tatcaacact tacgtctaac ccaacgtgcc aatcctttgg
    17341 ctacaatccc tgaggttcaa gtgattgact ttcgagacta tatcggacaa aatgagacgt
    17401 caaactttac gcctcctttg ctagaggcta tccaagaccg tctggttaaa aaagagcagg
    17461 tggttctcat gctcaatcgc cgtggttatt ctagctttgt catgtgtcgg gagtgtggga
    17521 cggtggatac ttgtcccaac tgcgatattt ctctgacctt gcatatggat accaagacta
    17581 tgaactgcca ttattgtggt ttctcgaagg atattcctca ggtctgtcct aactgtaaga
    17641 gccacagtat tcgttactat gggacgggaa ctcagaaggc ttatgatgag ctagcagaac
    17701 tctttcccca agttcgcatt ttgaggatgg atgtggatac gactcgaaag aaaggcagtc
    17761 accaagcctt gcttgaccag tttgggcgag gggaagcgga tattttactt ggtactcaga
    17821 tgattgcaaa gggtttggat tttcccaatg ttaccctagt aggagttcta aatgcggata
    17881 cggccttgaa tctgcctgat ttccgttctt ctgagagaac cttccagctc ttgactcagg
    17941 tggcaggtcg agcaggtcgg gctgaaaaag caggtcaagt cttgatacag tcctacaatt
    18001 cgcagcacta tgctattcga tttgccaagg atcaagatta cgaaggcttt tatgcctatg
    18061 aaatgggaat cagacgacaa ctcggctatc caccttacta tttcacgatt ggtattaccc
    18121 tttctcacaa gaaagaagaa gaggttttca aacgtgccta tgaagtcatg aacattttgc
    18181 ggtcaggctt gtcagagacc agtcccattc tggggccaac gccaaaaccg attgcccgta
    18241 cccgcaacct ctatcattac cagattttaa ttaaataccg tttagaagat gagctggggc
    18301 cgaccctcaa ccaggtcttg gccttgactc aagaacggga aaatagtgag ctccgtctca
    18361 gcattgacca tgagccgcag caatttttat aagaaggaga agatatgaca aaactaatct
    18421 ttatggggac ccccgacttt tcagcaacag tcttaaaagg acttttgaca gatgaccgtt
    18481 acgaaattct agccgttgtg acccagccaa accgtgctgt tggtcgtaaa aaagttatcc
    18541 aagaaacccc agtcaagcag gctgccaagg aagcaggact atctatctac caacctgaaa
    18601 aattatctgg aagtccagag atggaagatc ttatgaagct aggagcagat ggaattgtga
    18661 ctgctgcttt tgggcagttt ctcccaagca aactccttga tagcatggac tttgctgtca
    18721 acgttcatgc ctccctcctt cctagacacc gtggtggtgc gcctatccat tatgccttga
    18781 ttcaagggga tgaggaagct ggtgtgacca tcatggaaat ggttaaggaa atggatgcag
    18841 gagatatgat ttctcgtcgc agcattccga tcacagatga ggacaatgtt ggcaccttgt
    18901 ttgaaaaatt ggcgctagtt ggtcgtgatt tgcttttgga cactctgcct gcctatattg
    18961 ctggtgatat caaacctgaa ccgcaggata cgagtcaggt taccttctct ccaaatataa
    19021 agccagagga agaaaaactg gactggaaca aaaccaatcg tcaactcttt aaccaaattc
    19081 gtggaatgaa cccctggcct gttgcccata ctttccttaa gggcgaccgc tttaagattt
    19141 atgaagccct accagtagaa ggtcagggaa atccaggtga gattctctct atctgcaaga
    19201 aagaattgat tgtcgcaacg gctgaagggg ctctatccct caaacaagtg cagccagctg
    19261 gtaagcctaa gatggacatt gcttccttcc tcaacggagt tggacgtaca ttgactgtag
    19321 gagaacgatt tggtgactaa agtagaaacg gctagaagtt tagctctagc agtgctagag
    19381 gatgtttttg tgaatcaagc atattcaaat attgccttaa ataaacacct caaggggagt
    19441 cagctctctg cagcagacaa gggcttagtg accgagctag tctatggaac ggtagccctt
    19501 aaactgactc tggaatggta cctatcccac tttatcgaag acagagacca gttagacagc
    19561 tggctctatg tccttcttct catgagtgcc taccaactcc gctatttgga caagattcca
    19621 gatcatgctg tggtcaatga agcagtggaa ttggccaaac tccgtaaaaa aggcagtgaa
    19681 aaattggtca acgctgtcct tcgccgtatc ttgcgtgaag gctggccaga tattgctagc
    19741 atcaagcgaa aaaacaagcg tgactccatt gcctattctc tcccagtttg gctagttgcc
    19801 aaactcaagg aagaatacgg agaggagaga gcaaaagcca tctttgaaag cctgttagtg
    19861 cgaaacaaag ccagtattcg tgtaacagac ctaagtcgaa aagaggaaat ccaagccttg
    19921 ttggaggcga ataattccct tttagcaacc actggtctgg ttaaggagca ggggcatttt
    19981 gcagggcata atttgtttgc gaatggagcc attaccatcc aagatgagtc cagtcagctg
    20041 gttgctccga cgcttgattt acaaggtgat gagcgagtgc ttgatgcctg tgcggctcca
    20101 ggtgggaaaa cagcccatat agcctcttat cttacgacag gtcaggttac tgctctggac
    20161 ttgtacgacc acaagttgga tttaattcaa gaaaatgccc aacgtctggg agttgcagat
    20221 cgggttcaaa ctcaaaaatt ggatgccaga aaggtgcatg agttttttga ccaggattcc
    20281 tttgataaga ttttggtgga tgctccttgt tcaggaatcg gtcttttgcg ccgaaaacca
    20341 gatatcaaat acaataaaga aacggcagat ttcgcgtcct tgcaggaaat tcagttagaa
    20401 atattaggta gtgtttgtca aatactaggc aaaggtggta taataactta tagcacctgc
    20461 actatcgtct cagaggagaa ttttcaagtc gttaaggcct ttttagagag tcatcccgag
    20521 ttcgagcagg taaaactaga acatgaatgt aaggatatca tgaaagacgg ctgtatcctc
    20581 attacacctg aattgtatgg aagtgatgga ttcttcatca gtcaatttcg caagatatcg
    20641 gattaggaag gaactgacac atggaaattt cattattaac agatgttggt cagaaacgaa
    20701 caaataacca agactatgtc aaccactatg tcaatagagc tggacgtacc atgattattt
    20761 tagctgatgg gatgggaggt catcgcgcag ggaatatcgc tagtgaaatg gcggtcacag
    20821 acctgggtgt agcttgggtt gatacccaga tcgatacagt caatgaagtg cgtgaatggt
    20881 tcgcccatta cctagaaatt gaaaatcaaa agattcacca gcttggtcag gatgaagctt
    20941 acagaggcat gggaactact ttggaagtcc ttgctattat tgataatcag gctatctatg
    21001 ctcatattgg tgattcgcgt atcggcttga ttcgtggaga agaataccat cagttgacga
    21061 gtgatcattc tttggttaat gaattgctca aggctggtca attgacacca gaagaggcag
    21121 aagctcatcc gcaaaaaaat attatcaccc agtctattgg gcaaaaagat gaaattcagc
    21181 ctgattttgg gacagttatc cttgagtcag gtgactatct cttgctcaat agtgacggct
    21241 tgaccaacat gatttcaggc agtgagattc gtgatattgt aaccagtgat attcctttag
    21301 cagataaaac ggagacactt gttcgttttg ctaacaatgc aggaggttta gacaacatta
    21361 cggttgccct tgtttctatg aacgaggagg atgaagaatg atccaaatcg gcaagatttt
    21421 tgccggacgc tatcggattg tcaaacagat tggtcgagga ggcatggcgg atgtctacct
    21481 agccaaagac ttaatcttag atggggaaga agtggcagtg aaggttctga ggaccaacta
    21541 ccagacggac ccgatagctg tagctcgttt tcagcgtgaa gcgagagcta tggcagatct
    21601 agaccatcct catatcgttc ggataacaga tattggtgag gaagacggtc aacagtatct
    21661 tgcaatggag tatgttgctg gactagacct caaacgctat atcaaggaac attatcctct
    21721 ttctaatgaa gaagcagtcc gtatcatggg acaaattctc ttggctatgc gcttggccca
    21781 tactcgagga attgttcaca gggacttgaa acctcaaaat atccttttga caccagatgg
    21841 gacggccaag gtcacagact ttgggattgc tgtagccttt gcagagacaa gtctgaccca
    21901 gactaactcg atgttgggct cagttcatta cttgtcacca gagcaggcgc gtggttcgaa
    21961 ggcgactgtg cagagtgata tctatgccat ggggattatt ttctatgaga tgttgacagg
    22021 ccatatccct tatgacgggg atagcgcggt gaccattgcc ctccagcatt tccagaaacc
    22081 cctgccgtcc gttattgcag aaaatccatc tgtacctcag gctttagaaa atgttattat
    22141 caaggcaact gctaaaaagt tgaccaatcg ctaccgctcg gtttcagaga tgtatgtgga
    22201 cttgtctagt agcttgtcct acaatcgtag aaatgaaagt aagttaatct ttgatgaaac
    22261 gagcaaggca gataccaaga ccttgccgaa ggtttctcag agtaccttga catctattcc
    22321 taaggttcaa gcgcagacag aacacaaatc aatcaaaaac ccaagccagg ctgtgacaga
    22381 ggaaacttac caaccacaag caccgaaaaa acatagattt aagatgcgtt acctgatttt
    22441 gttggccagc cttgtattgg tggcagcttc tcttatttgg atactatcca gaactcctgc
    22501 aaccattgcc attccagatg tggcaggtca gacagttgca gaggccaagg caacgctcaa
    22561 aaaagccaat tttgagattg gtgaggagaa gacagaggct agtgaaaagg tggaagaagg
    22621 gcggattatc cgtacagatc ctggcgctgg aactggtcga aaagaaggaa cgaaaatcaa
    22681 tttggttgtc tcatcaggca aacaatcctt ccaaattagt aattatgtcg gccggaaatc
    22741 ttctgatgtt atcgcggaat taaaagagaa aaaagttcca gataatttga ttaaaattga
    22801 ggaagaagag tcgaatgaga gtgaggctgg aacggtcctg aagcaaagtc taccagaagg
    22861 tacgacctat gacttgagca aggcaactca aattgttttg acagtagcta aaaaagctac
    22921 gacgattcaa ttagggaact atattggacg gaactctaca gaagtaatct cagaactcaa
    22981 gcagaagaag gttcctgaga atttgattaa gatagaggaa gaagagtcca gcgaaagcga
    23041 accaggaacg attatgaaac aaagtccagg tgccggaacg acttatgatg tgagtaaacc
    23101 tactcaaatt gtcttgacag tagctaaaaa agttacaagt gttgccatgc cgagttacat
    23161 tggttccagc ttggagttta ctaagaacaa tttgattcaa attgttggga ttaaggaagc
    23221 taatatagaa gttgtagaag tgacgacagc gcctgcaggt agtgtagaag gcatggttgt
    23281 tgaacaaagt cctagagcag gtgaaaaggt agacctaaat aagactagag tcaagatttc
    23341 aatctacaaa cctaaaacaa cttcagctac tccttaaaag cagatggata atcaaaatga
    23401 gtaatcaatc tttgtcatga tttcatggca aagatttttt ttgagtccag atttgtgata
    23461 gaatagaggg agttgataaa aggaggaaag catggaagaa tcaaaagaat taaatgccgt
    23521 cattgatgtg attatgctag cggggactat tctccttaaa agtggctcag aaatccatcg
    23581 tgtagaagat accatgattc gaatcgcgca ttcgcagggg attgtggatt gcaatgtcct
    23641 tgccatgcct gccgctatct ttttctctat tgaaaatacc aatatttcgc gcatgaagcg
    23701 cgtgacctcc tcttcttata acatcgaaaa agtctgcgat gtgaaccaga tttctcgtca
    23761 gctagttggg gggcagattg acttagaaac agcctttaag caattgacgg ccttgcaagc
    23821 tcaacccctt ccctatacta agttgcaggt aactctggct gcgaccttta gtgctccttt
    23881 cttttcagtt atgtttagcg gaaatatcta cgacgcactt ggtgcaggag tggcgacctt
    23941 atttggtttt gccttttccc tctatgtgga aaaatttatc cgaattccct ttgtgacagc
    24001 ctttgctgga gcctttgtct ttgggataat tgcccagttt tgggctcgct acacaggttt
    24061 tccttcaacg gcagatttga ttatagctgg tgcggtcatg ccgtttgtac caggtattgc
    24121 cttgaccaat gcggtccgtg atattatgac caaccacata aactctggta tgagtaagat
    24181 gtttgaatcc ctgctcatta ccctcgcttt aggggcagga acttctgtcg ccttggtatt
    24241 gatgaactaa tatgacacta acaacctttt tattacaagc agtagcaagt tttcttgcca
    24301 ttatcacttt tttaatcgta ctcaatgtgc aacggtctat gctcttacct ggagggattt
    24361 tgggcatgac tgtctggcta atctatctct tgctcaagga accgaccaat gtcattgtag
    24421 ctaccttcat tgcagccatt attggttctt gtgtcagcca gattttaagt attctttata
    24481 agacacctgc tgtggtcttt atcttggcca ttttggcacc gctggttcca ggttatctct
    24541 cctaccgaac aactgccttt tttgtgacag gggactataa taaagcactg gcaagtgcga
    24601 ccttggttgt catgttggct ttggtaatct ctattggaat ggctagcgga acagtgattc
    24661 tcagactgta tcattatata aaaacacatc gagtatcgta gactttacag aaataaaaga
    24721 attttctgaa aaatgagata aataaattaa caacgctttc tatatgtgcg agaataccgc
    24781 acttatgaag aaattgcgac tgattttggt atccacgaaa gcaacttact ccgtcggagc
    24841 caatgggttg aagtaactct tgttcaaagg tggtgttacg atttcaagaa ctcctctcag
    24901 ttctgaagac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaaa
    24961 caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
    25021 acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca tgatatgaag
    25081 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
    25141 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    25201 aagctgctaa cagttgaaga taaagcctat aaccatgcgc tatctaagga gagaagcaag
    25261 gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
    25321 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    25381 ggattctagt tttgcaggaa gtctactact ttccttattg tctgtaaatc tactgacctt
    25441 gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg gatggcaaga
    25501 gcatcaattg attgctgaga aggttagtaa aacacttgat aagacatttg ataaggatgt
    25561 cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg gaaggactta
    25621 ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata aagctactta
    25681 tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata agaggcttga
    25741 tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa tagtatagaa
    25801 cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt gataagattg
    25861 gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg aggggaattg
    25921 accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg cccctaactg
    25981 aggatatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag caagaaagac
    26041 aagaagttga catggtcatt gtggcgaccg agtcaggaat tgaccagagt aaggctgcgg
    26101 ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc gagattaaag
    26161 aagcctgcta tggggcgact gctgccctcc attatgccaa attgcatgtg gaaaattctc
    26221 cggagtccaa ggtcttggtc attgcaagtg atattgccaa atacggtatt gaaactccgg
    26281 gagaacccac tcagggtgcc ggaagtgtgg ctatgttgat tacacaaaat ccacgcatga
    26341 tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc tggcgaccaa
    26401 attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac ttggatagtt
    26461 tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactttggat gattttgcgg
    26521 ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg
    26581 ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac cagtctattc
    26641 tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga cttttgtctc
    26701 tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgccctttat agttacggaa
    26761 gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa gcttatttgg
    26821 ataaagaccg cttgaacaag ctcaaccaac gaactgtctt atccgttgca gactatgaaa
    26881 aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt gctggctatg
    26941 aaaatcaaga ttttgccttg gttgaaattc tcgaccacca acgccgttat agcaaggttg
    27001 aaaaataatg aagataagtt ggaatgggtt ttctaaaaaa tcataccaag agcgcctcga
    27061 gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg agaaggatga
    27121 acagatgagt gtgactgtgg cagaccagct gagtgagaat gtagtgggaa ctttttctct
    27181 gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg ttccctatgt
    27241 gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc
    27301 aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag ccctttatca
    27361 agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg agctcttgga
    27421 gcttgccaat caagcctatc cttctatcgt taaacgtggg ggtggggcgc gtgacctgca
    27481 tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg tcgataccca
    27541 ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac cagtcttaga
    27601 agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga ccgattctct
    27661 ggtgactgca agctgtcgca tggcctttcg ctacttgagc cgccaaaagg atcaaggacg
    27721 agagattgcg gagaaaattg cgttggctag tcagtttgcg caggatgatc cttaccgagc
    27781 tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg ccactggtaa
    27841 tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg gacgctatca
    27901 aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg agatgaccct
    27961 gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg tagctctcag
    28021 tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg tgtctatcgg
    28081 tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc agcaaggcca
    28141 catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat ctgaagttgc
    28201 tcccctagtc gagcagctta tcgcagataa aacctttaac ctagagacag cccagcgcta
    28261 tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt cttgtgttta
    28321 aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg tgacttcctt
    28381 gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt ccaaaggttg
    28441 cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat catagccgat
    28501 gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa tgaccagaat
    28561 agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca agatattctt
    28621 gatttccatt tcttttctga cgggagaaaa gtcactggaa acattgataa taggagcttt
    28681 tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg aattgtcatt
    28741 ccctgtaatc atgatgatag actgggcacc tgtcttgacc aaggtttggg cagcaagaac
    28801 cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt ttcggtcaaa
    28861 ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt gactaccaga
    28921 aatgatgccg tccacctgat tggcttccaa catttcgatg tattcacgtt ccttctcaga
    28981 atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt ggtgttccaa
    29041 tttatcaatc aattctgcat agaaaacatt ggaaatattg gggaaaatca agccgattaa
    29101 cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc ccaattctcg
    29161 catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt tattgataac
    29221 ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta gttttgcgac
    29281 cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg ataccatttt
    29341 ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg atgaaaattt
    29401 caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg atagggcaag
    29461 aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga tccactgtca
    29521 cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta tcagcaagta
    29581 agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa gtgttcttgg
    29641 tttgggaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata gcagcgactg
    29701 gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag aaggttcctt
    29761 ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag ctaactgcta
    29821 gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa ccgtaatcca
    29881 tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag gaagccccaa
    29941 tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc aatccttgtg
    30001 gacagtagag aaggacaggt tgttcctcta caaagaccag attaggacat tccatcatgt
    30061 aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt gtgtagtcgt
    30121 tattgacagc cttgtagaga cgaacgaaac cttttttctc caagtcctgt ccaccgacga
    30181 cagcatagta ttgaccttta aagttaaaaa tttgtggatc gcggaagtgg tcagtagagt
    30241 ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc ttgtccatca
    30301 aagcaccgat ctggtatggg tgacggatcc agttttcatc gcgaacattt cctgtataaa
    30361 ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg tggctatcta
    30421 atggagtatc tggtaaaact ttgattccag tttctttaaa gtgaaccaaa tcatcacttt
    30481 ctagctgtgc ccaagatttt aaaccgtggg ctgcaccaaa aggaaaattc tggtaaaaga
    30541 ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt cctgtttttg
    30601 gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt atatgttgaa
    30661 tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc cattccattc
    30721 attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa atgcaagcct
    30781 tttatgttaa aaaagaggaa aaactgtcaa aggattatca taaaataaat acaggaaatc
    30841 aatcaaattt ttacgaaaat gtgaaagata atgaaataaa agacttttta accaaggttt
    30901 caaacttatt tttcaaggaa ttcctgatga aacagtcaaa aacaatcaat ctaaagcttg
    30961 cccactaagt ggatagaata tttttctgca aaacgcttga catattttta aaacatgata
    31021 aaataatagt cgtaagggcg aataaaatcg ctttcaaaca agaacaaaat gttatataag
    31081 gagatttttg caaatgaaca atcaggaaat tgcaaaaaaa gtcatcgatg ccttgggcgg
    31141 acgtgaaaat gtcaatagtg ttgcccactg tgcgactcgt ctacgtgtca tggtcaaaga
    31201 tgaagagaaa atcaataaag aagtgattga gaacttggaa aaagttcaag gtgctttctt
    31261 taactcaggg caataccaaa ttatctttgg tacaggtaca gttaacaaaa tgtacgatga
    31321 agttgttgta cttggcttac caacatcatc taaggatgac atgaaagcag aagttgctaa
    31381 acaagggaac tggttccaac gtgctatccg tacttttggt gatgttttcg ttccaatcat
    31441 cccagttatc gtagcgacag gtctcttcat gggtgtgcgt ggtcttttca acgctcttga
    31501 aatgccactt ccaggtgact ttgcaactta cacacaaatc ttgacagata cagccttcat
    31561 catcttgcca ggtttggttg tgtggtcaac cttccgtgta tttggtggaa atcctgccgt
    31621 tggtatcgtt cttggtatga tgcttgtctc tggctcactt ccaaacgctt gggcagttgc
    31681 tcaaggtggt gaagtaacag cgatgaactt ctttggtttc atccctgttg ttggtttgca
    31741 aggttccgtt cttccagcct tcatcatcgg ggttgtcgga gctaaatttg aaaaagctgt
    31801 ccgcaaggtt gttccagatg tcattgacct cttggtaaca ccattcgtga cacttttggt
    31861 catgtctatc cttggactct ttatcattgg accagttttc cacgttgttg aaaactacat
    31921 ccttattgct acaaaagcga ttcttagcat gccatttggc cttggtggtt tcttgattgg
    31981 tggggttcac caattgatcg tcgtgtcagg tgtgcaccac atcttcaact tgcttgaagt
    32041 gcaattactt gctgctgacc atgctaaccc attcaacgct atcatcacag ctgctatgac
    32101 agctcaaggt gctgctactg ttgcggttgg tgttaaaaca aaaaatccaa aactgaaaac
    32161 acttgctttc ccggctgctc tttctgcctt cctaggtatt acagagcctg ctatcttcgg
    32221 ggtgaacttg cgcttccgta aaccattctt cctttcattg attgctggtg caatcggtgg
    32281 tggattggct tctatccttg gacttgctgg tactggtaat ggtatcacca tcatccctgg
    32341 tacaatgctt tatgttggta acggacaact tccacaatac cttcttatgg tagctgtatc
    32401 atttgccctt ggttttgctc ttacttacat gtttggttac gaagatgaag tagacgcaac
    32461 tgcagctgca aaacaagctg aagtggctga agaaaaagaa gaagttgcgc cagcagctct
    32521 tcaaaatgaa acacttgtaa ctcctatcgt cggtgatgtt gtcgctcttg ctgatgtcaa
    32581 tgacccagtc ttctcaagtg gagctatggg acaaggtatc gctgtgaaac caagccaagg
    32641 cgtggtctat gcaccagctg atgctgaagt ttcaattgcc tttccaacag ggcacgcttt
    32701 tggtttgaaa acaagaaatg gtgctgaagt tttgattcat gttggtattg atactgtatc
    32761 tatgaacggt gacggttttg aaacaaaagt tgctcaaggt gataaggtga aagttggcga
    32821 tgttcttgga acatttgact caaacaaaat cgctgcagct ggacttgatg atacaacaat
    32881 ggttatcgtt acaaatacag gtgactacgc ttcagtagct ccagtcgcaa caggttcagt
    32941 tgctaagggg gatgctgtga tcgaagtgaa aatctaatca atcctctcta atgtgaaaac
    33001 gaacaaatga catatttgtt cgtttttatt agatagtaag atttacagag gaaaatctaa
    33061 aaaatagaga catttagact ttcgaagtat gctataataa agaaaataaa aacaagaggt
    33121 ttatcatgac aaaattatat ggaagcttgg aagcgggcgg tacaaagttt gtctgtgctg
    33181 tcggtgatga aaactttaac gttgtagaaa aaacacaatt tccaacaaca actccaatcg
    33241 aaacaatcga taaaaccatt gagttcttct caaaattcga taaccttgct ggtcttgcag
    33301 ttggttcatt tgggccgatt gatattgaca aaaactcaaa aacttatggc tttatcacga
    33361 cgactccaaa accaaactgg gcaaatgtgg acttgcttgg tgcccttcgt cgcgccctaa
    33421 atgtgccaat gtacttcaca acagacgtaa acagctctgc ttacggtgaa gtggttgccc
    33481 gtaacaatgc tggtggtcgt atcgaaaact tggtttacta cacaatcggt acaggtatcg
    33541 gtgcaggtgt catccaacgt ggtgagttta tcggtggtgt gggtcaccct gaaatgggtc
    33601 attattatgt tgctagacac ccaatggata ttgaaaaaga gtttaagggt gtttgtcctt
    33661 tccataaggg atgtctagaa ggttatgcag ctggtccaag tttggaagct cgtacaggtg
    33721 tacgtgggga aactattgaa ctcaacaacc ctgtttggga tgttcaagcc tactatatcg
    33781 ctcaagctgc ggttaatgcg acagtgactt tccgcccaga cgtgattgtc tttggtggag
    33841 gggtcatggc tcaacaacat atgctggacc gtgtccgtga gaaatttaca tctcttctta
    33901 atggttacct accagtacca gatgtgcgtg actatatcgt gacgccagca gtcgcaggaa
    33961 atggttctgc cacacttggg aactttgttc ttgcaaaaga agtttcaaaa taaagcacaa
    34021 aatccgcttg ggaaaccaaa cggatttttt acgtgtcaaa gcatttgcca gaaaaagtca
    34081 ataatatagg tcagaccgta ggtataaacc acgagggtaa agggtttggt cagaatgatg
    34141 atggtcatgt agcgcttgaa actcatcttg gtcagggcag ccagcataca gagaaagtca
    34201 gctgggctaa tgggccaaat catcataaaa ataaagaagc ggtcaaaacg attgccctta
    34261 tctagccagc cgatgtactt gtcgtaggtg cgcttgctga cgacagactg gacaaaggca
    34321 gctccgtata ggcgcactag ataaaagata atggcacagc caatcacgat gccgatatag
    34381 ttgtagatag tcccgatgat gtgcccgtag ataaagaccc cagccaccga ggtcaaggcc
    34441 cctggaatga tagggacgac agtctgtaaa atctgtaaaa agataaagag aggtggaccc
    34501 cagatgcctg cctgctggat aaaggcagag agggtttcct tggattgtaa aatcccagcc
    34561 tgataagccc aaatacagaa aatcaaactc ccaaccccac cgacaatcga tgagatattg
    34621 ataactcgct gcagaagggg agaaacagct ttcatttgtt tatcctgtga catgtaaact
    34681 cctcatagat agtatatttc tactatacca tattttggag gagaaagggg gaatgagtct
    34741 tttttgataa ggaatagaaa gtaaatagcc cttcgagact tagaataggt ctgtcaacta
    34801 aaggttatat gcattctagg tttcgaataa tcgcaattcc ataaatttaa aagtattcta
    34861 agtttcgaat agcttatctg ggataatttt gaggcattcg cgctttcgaa tagtcatttt
    34921 ccctaaagtt tatatgtatt ctgaagctag aaagactaaa atataaaagt agtaagagtc
    34981 tctctctgat ggacgtaatt tatggctagt atgaatcctt tgaattgtta gttaatttta
    35041 atattaatca gttctgaaat aattactaaa tatagttaga tggtgagtta attattgcta
    35101 aatttcaagt tcaagttagt catccagaag tcttctctgg gggacttgta gttcaagcat
    35161 tttttaggat agttgttaat ccacttttcg ataaatgcga cttcctttgt agttgttttc
    35221 ttagttccct gaggtaacca tctatgaatg agcctgttgt gattttcatt agatcctata
    35281 gtgatgtgca taatagatat agcagattga aactagaata gtatacatct acttctaaaa
    35341 cattgttaga aatcaatttg actgtcctga tcaatttgtc ctgtttttat ttcattttac
    35401 tatataatcc ttagaaaaca tatcggacaa gcggttgaat tccgttccgt ccattagtag
    35461 ataaaggatt actccttctt gaaatgacag atgaacttgt ttcttataaa aatgttgtct
    35521 gaaactatta gcctttttcc agaagtttta gaggaagaaa actttacgag gaaaaaggag
    35581 ttactcaaat aacaattcag gattaaaaat agacagttga ggagcggaag gtataaatta
    35641 agtttgctac tgtataatgg atttatcact aatactcttc gaaaatctct tcaaaccacg
    35701 tcagcttcgc cttgccgtag atatagttac tgacttcgtc agttctatcc acaacctcaa
    35761 aacagtgttt tgagctgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc
    35821 agcctacggc tagcttccta gtttgctctt tgcttttcat tgagtataaa agtgctccag
    35881 gccatatttt acacagcaat agtcttctaa aaatggacaa aaacattgta aaggctatca
    35941 aaaaggagta taatgagtgc aagaaatttc ggaggtgaaa gatgctagaa gtaagaagtc
    36001 tagagaaaag ttttggctcc aagcaagttt tgtttggtat tgactttcaa gcgcgaccag
    36061 gtcgtatttt gggactagtc ggaaaaaatg gtgctggaaa aacaacgatt ttccatagta
    36121 ttttgaaatt cctagaatat cagggagaaa tcggtctgga tggtcaggat attcgtcagg
    36181 agacctatgc tcggattggt tatctgcctg aagaacgcag tctcatgcct aaattgacag
    36241 ttcttgaaca agttcgctac ttggcgactc taaaaggcat ggatgccaaa gaagtcaaag
    36301 aaaaactccc tcaatggatg aagaggttgg aagtgaaagg aaagctgaca gataaaatca
    36361 agagtctgtc aaaaggaaat cagcagaaga ttcagctcat tattactctg attcatgaac
    36421 cagacctgat tatcttggat gagcctttta gtggattgga cccagttaat acagaattgc
    36481 tcaaacaagt catttttcag gaaaaagagc gcggagcaac cattatcttt tctgaccatg
    36541 tcatgaccaa tgttgaggaa ctttgtgacg atattctgat gatccgagat ggccgtgtgg
    36601 tcttgcacgg accagttcag gatgtccgca atcaatacgg gaaaacgcgt ctctttgttt
    36661 caagtgaacg aagcaaggaa gaattggaaa atcttcctca tgtcaaacag gtgagcttga
    36721 ccaaacaagg cagttggaaa ttgattttgg aggatgagag cgctggaagg gaactcttcc
    36781 caatcttgac tcaaggtcaa tatatcgcaa catttgacca acaagcgcca actatcgatg
    36841 aaatctttaa actagaatca ggagtggaag tatgagaaat atgtgggttg taatcaagga
    36901 aacctatctt cgacatgtcg agtcatggag tttcttcttt atggtgattt cgccgttcct
    36961 ctttttagga atctctgtag gaattgggca tctccaaggt tcttctatgg ctaaaaataa
    37021 taaagtggca gtagtgacaa cagtgccatc tgtagcagaa ggactgaaga atgtaaatgg
    37081 tgttaacttc gactataaag acgaagcaag tgccaaagaa gcaattaaag aagaaaaatt
    37141 aaaaggttat ttgaccattg atcaagaaga tagtgttcta aaggcagttt atcatggcga
    37201 aacatcgctt gaaaatggaa ttaaatttga ggttacaggt acactcaatg aactgcaaaa
    37261 tcagcttaat cgttcaactg cttccttgtc tcaagagcag gaaaaacgct tagagcagac
    37321 aattcaattc acagaaaaga ttgatgaagc caaggaaaat aaaaagttta ttcaaacaat
    37381 tgcagcaggt gccttaggat tctttcttta tatgattctg attacctatg cgggtgtaac
    37441 agctcaggaa gttgccagtg aaaaaggcac caaaattatg gaagtcgttt tttctagcat
    37501 aagggcaagt cactatttct atgcgcggat gatggctctg tttctagtga ttttaacgca
    37561 tattgggatc tatgttgtag gtggtctggc tgccgttttg ctctttaaag atttgccatt
    37621 cttggctcag tctggtattt tggatcactt gggagatgct atctcactga ataccttgct
    37681 ctttattttg atcagtcttt tcatgtacgt agtcttggca gcattcctag gatctatggt
    37741 ttctcgtcct gaggactcag ggaaagcctt gtcgcctttg atgattttga ttatgggtgg
    37801 tttttttgga gtgacagctc taggtgcagc tggtgacaat ctcctcttga agattggttc
    37861 ttatattccc tttatttcga ccttctttat gccgtttcga acgattaatg gctatgcggg
    37921 gggagcagaa gcatggattt cacttgctat tacagtgatt tttgcggtgg tagcaacagg
    37981 atttatcgga cgcatgtatg ctagtctcgt tcttcaaacg gatgatttag ggatttggaa
    38041 aacctttaaa cgtgccttat cttataaata gaagagcctt gcgaaagcga ggtttttaaa
    38101 gatgaaaagg atggaatcac gaacctaatt atgtacacat tatgtaaaca ggttgcttga
    38161 aaactcaatt gtatagtgaa ctgaatctgg aataggataa tattacttct aaaacattct
    38221 tataaattga tttgaattcc aaaatcccat cgttccgttc ttatttcatt ttgcgatata
    38281 gtgaaaggaa ataagtcagc tcacaaaaaa cgcataatat caaggatttt taacacttga
    38341 tactatgcgt tttctaattt taaagacttt ttgcctggtc tcttttgttc tatgagtatg
    38401 ttacatatct aggtaaaaat tatttaaagc aaattaacct tatttctcaa gatgtagtag
    38461 gttccgagat aaaagatagc tatgaatatg agttctttaa caatggctat acctgctccc
    38521 atatagaaat ggtcattgag tcctaccagt gaattgacat agaaattaga actaagattg
    38581 aagaaaagtt caataaatcc aatgacgatt tggataccaa tgtaggctgc aacagcgagt
    38641 gctgtacggt attcattgaa aagctgtcca atggaaatag ccaggtagat gcagaggatt
    38701 cctgaaatgg tatttagtag gaaggatata cctgtaagaa agatctgagg gagatgtgtt
    38761 tctacaaatg taatcacata agaaagagga atccattctg gagctgttaa agccagaata
    38821 ataacagcac ttagagccaa tacagcggtg ctaatcaatg accagataaa ggcaccgatt
    38881 agtttggctg tgatgatatg gtgttcagaa actggcaagg tcaaagtcag atagccttgt
    38941 cggtcgtaga cactaccttt gaagcgttta ataatcaaga aaatggttga aatcgcaagt
    39001 gtaagcatca agccaccaaa gactgtagct agaaaaagta gcatagtagc ctgactttct
    39061 tggtaaggta gatttttaaa gccttgtgtc tgtattccga tgagggcaga aaggactagc
    39121 acggctgcgt agagggctaa ataccacttg ttaacatttt taaattcgta gtgaactaaa
    39181 ttccaaaaca taaataatct cctttgctta ggccttaaat tcctgacgga agagttggtc
    39241 aatggattca cctgactcgt agcgaatatc atctacattt ccttgacgga cgacttttcc
    39301 gtcttttagg aagacaattt catccaagat tggctcgata tcagaaatca agtgggtaga
    39361 aatcaaaacg gtagaagttg gtgagtagtt gttgataatg gtattgagga tataagcacg
    39421 ggctgctgga tccaccccac caatgggttc atccaaaaca tagagacgag catcacggct
    39481 cataaccaaa atcagttgaa ccttttcttt gtttcctttt gatagtttct tgagacgact
    39541 attttcatca atgcccaggt ctgcaagtag atgatgagcg cgttcaagat tgaaatcttt
    39601 atagaaggtc ttgaagtagg ttagggcttc tttgaccttc atttgctcat tgagataggt
    39661 cgtatcaggc aaataagcta caacggcctt ggttgctggg cttgggtcca tgtcgttgat
    39721 gaggacacgt ccttgatctg gttgtaagag gccattaatt agtttaatca gggttgtttt
    39781 tcctgagccg tttggcccaa gaaggccgac aatttttcca gctggaatgt caagagaaac
    39841 attttcaagg gctggtgttg ctccatatga tttggataca ttttcaaata ctagtaatga
    39901 cataggctta aactccttta atataatcac tgactacgcc tggtagttct tctttttcat
    39961 agccaaaatg gatcatggag gaaacgaagt gttccaattc ttcttctgat aattgtttgc
    40021 gtgactgagc gattagctcc ttatccttag tcacaaatcg tccagttgtt cgcttgctgt
    40081 agacaaatcc ttctcgttca aggtctgata aggctctttg gatggtattg ggattgacac
    40141 cagcctcgct agctagctcc ctcacggttg gaagttgttg attgggttcc agtgtatggg
    40201 aaacaatctg aagcttgatt ttctccataa tctgtaaata gatgggtttt ttgttgtcaa
    40261 atgtccagga catcttagtc tcctttctct tatccttttg tcttaactaa ataatacaac
    40321 aaaacaaaaa acttgtcaag caaaaagaag aattgttttg ggaatcgctt aaaaaatggt
    40381 ataatgaaaa gaaaacgata aggagggaaa ggatgcgttg tccaaaatgt ggggctacca
    40441 agtcaagtgt tatcgatagt cgccaagcag aagaagggaa caccattcgt agaagacgtg
    40501 agtgcgacga atgccaacac cgttttacaa cctacgaacg agtagaagaa agaaccttag
    40561 tggttgttaa aaaagatggt acacgggaac aattctccag agataaaatc tttaatggga
    40621 ttatccgctc agcccagaaa cgtcctgtgt caagtgatga aatcaacatg gtagtcaatc
    40681 gtatcgaaca gaaactccgt ggtcgaaatg aaaatgaaat tcaaagtgag gacattggtt
    40741 cactcgtcat ggaggagttg gctgaattgg acgagattac ctatgtacgt tttgctagtg
    40801 tctatcgtag ttttaaggat gtcagtgagt tagagagctt gctccaacaa atcacccagt
    40861 cctctaaaaa gaaaaaggaa agataaatga agccaattga ccgtttttct tatctaaaga
    40921 ataatcgggt gtcgcaagat acctcatctc tggtacagtg ctacctcccg attatcggtc
    40981 aggaggcact gagcctttat ctttatacaa tcagtttttg ggataatggt agaaaggaat
    41041 atcttttttc aagtatcctc aatcatctca actttgggat ggatagactg ataaaatcat
    41101 tgaaaatctt atctgctttt aatctcttga ccctctatca aaagggggat gtttatcagc
    41161 tagccctcca tgctcctcta tctagtcaag acttcttgga gcatcctgtt tatcgcagac
    41221 tcttagagaa aaagattggc gactctgctg tggaggattt gaaagttgaa agtgctgatg
    41281 gtgaagaaat acctgtctca ctcaatcaag tctttccaga attggcagaa ctaggcagtc
    41341 aagaagacct tggtctcaag aagaaagtgg ccaatgattt tgacttggaa cattttcgcc
    41401 agctgatggc tcgagatgga cttcgttttg cggatgagca gtccgatgtc ttaaacctct
    41461 ttgctattgc cgaggagaag aaatggactt ggtttgaaac ctatcaattg gccaagtcaa
    41521 cagctgtttc tcaggttatt tcaaccaaac gcatgcgtga aaaaattgct caaaaaccag
    41581 tttcctctga ctttaatcct aaggaagcaa ccattatcaa ggaagctaaa agtaagactg
    41641 ccctgcagtt cttagcagaa atcaagcaaa cacgcaaggg gaccattacc caaacagaaa
    41701 gagaactttt gcaacagatg gctggcttgg gcttgctgga cgaagtcatc aatatcattc
    41761 tcttgttgac ctttaataag gtggattcgg caaacatcaa tgagaaatat gccatgaagg
    41821 tggctaatga ctatgcctat caaaagatac attcagcaga agaggccgtt ttacgaattc
    41881 gtgagcgagg gcagaaaaca aaaacacaaa aacagaatca gactgcccca gcaaaaacca
    41941 atattcctaa atggagtaac ccagattata agaatgaaac cagcgaggaa actcgtctgg
    42001 aactagaacg taagaaacaa gaactattag ctcgattaga aaaaggagga gattagatgg
    42061 aaagtgtcgg agacgtactc aaacgtcaac ccagccgttt ttattatcaa gatttggtcc
    42121 agaaaatcat gaaggaccct gatgttgcgg cttttatcca gcaagaatcc ttgactccag
    42181 aggaattaaa tcgcagtatc tccaagttta atcagtacat caccgagcgt gacaagtttc
    42241 tccgtgggga tacggattat attgccaaag gctacaagcc gattttggtt aagaatcatg
    42301 gctatgcaga tgtttcatat gaagaaactc ctgagctaat cgcggctgaa aaagaagcgg
    42361 ctattaagaa tcgtctcaag ctaatcaatc taccagccag tctcaaaaaa gctagtttgg
    42421 ctcaagttga tttggatgat ttgggacgct tgccagtttt tgaaaaacta ttagcctttg
    42481 tggagcaata tccagctatt cgaaaaggtc tttacttata tggagacttt ggtgtgggta
    42541 aaagtttcat ggtggcggcc ttagctcatg atttatcaga aaaacgtggt gtttcatcaa
    42601 ctctcctcca ctatcctagc tttgtcattg atgtcaaaaa tgctatcagt gatggcaatg
    42661 ttaagacctt ggtggatgag attaagctgt ctgaggtcct gattttagat gatattggcg
    42721 ccgagcaatc aaccgcttgg gtgcgtgacg aaatcctgca ggtcattctc caatatcgga
    42781 tgcaggaaaa tttaccgacc tttttcacat ccaacttcaa ctttgaagat ttggagaagc
    42841 attttgcgaa agtgaaacat ggaaatgacg aaacctggga agccagacgg gtcatggaac
    42901 gcatccgtta tttggctgag gagactcgtt tagaaggagt aaaccgtcga tgacagaaac
    42961 cattaaattg atgaaggctc atacttcagt gcgcaggttt aaagagcaag aaattcccca
    43021 agtagactta aatgagattt tgacagcagc caagatggca tcatcttgga agaatttcca
    43081 atcctactct gtgattgtgg tacgaagtca agagaagaaa gatgccttgt atgaattggt
    43141 acctcaagaa gccattcgcc agtctgctgt tttccttctc tttgtcggag atttgaaccg
    43201 agcagaaaag ggagcccgac ttcataccga caccttccaa ccccaaggtg tggaaggtct
    43261 cttgattagt tcggtcgatg cagctcttgc tggacaaaac gccttgttgg cagctgaaag
    43321 cttgggctat ggtggtgtga ttatcggttt ggttcgatac aagtctgaag aagtggcaga
    43381 gctctttaac ctacctgact acacctattc tgtctttggg atggcactgg gtgtgccaaa
    43441 tcaacatcat gatatgaaac cgagactgcc actagagaat gttgtctttg aggaagaata
    43501 ccaagaacag tcaactgagg caatccaagc ttatgaccgt gttcaggctg actatgctgg
    43561 ggcgcgtgcg accacaagct ggagtcagcg cctagcagaa cagtttggtc aagctgaacc
    43621 aagctcaact agaaaaaatc ttgaacagaa gaaattattg tagaaagtga gaaattatgg
    43681 ccctaccaac tattgccatt gtaggacgtc ccaatgttgg gaaatcaacc ctatttaatc
    43741 ggatcgctgg tgagcgaatc tccattgtag aagatgtcga aggagtgaca cgtgaccgta
    43801 tttatgcaac gggtgagtgg ctcaatcgtt cttttagcat gattgataca ggaggaattg
    43861 atgatgtcga tgctcctttc atggaacaaa tcaagcacca ggcagaaatt gccatggaag
    43921 aagcagatgt tatcgtcttt gtcgtgtccg gtaaggaagg aattaccgat gcagacgaat
    43981 acgtagcccg taagctttat aagacccaca aaccagttat cctcgcagtc aacaaggtgg
    44041 acaaccctga gatgagaaat gatatctatg atttctatgc tctcggtttg ggtgaaccat
    44101 tgcctatctc atctgtccat ggaatcggta caggggatgt gctagatgcg atcgtagaaa
    44161 atcttccaaa tgaatatgag gaagaaaatc cagatgtcat taagtttagc ttgattggtc
    44221 gtcctaacgt tggaaaatca agcttgatca atgctatctt gggagaagac cgtgttattg
    44281 ctagtcctgt tgctggaaca actcgtgatg ccattgatac ccactttaca gatacagatg
    44341 gtcaagagtt taccatgatt gatacggctg gtatgcgtaa gtctggtaag gtttatgaaa
    44401 atactgagaa atactctgtt atgcgtgcca tgcgtgctat tgaccgttca gatgtggtct
    44461 tgatggtcat caatgcggaa gaaggcattc gtgagtacga caagcgtatc gcaggatttg
    44521 cccatgaagc tggtaaaggg atgattatcg tggtcaacaa gtgggatacg cttgaaaaag
    44581 ataaccacac tatgaaaaac tgggaagaag atatccgtga gcagttccaa tacctgcctt
    44641 acgcaccgat tatctttgta tcagctttaa ccaagcaacg tctccacaaa cttcctgaga
    44701 tgattaagca aatcagcgaa agtcaaaata cacgtattcc atcagctgtc ttgaacgatg
    44761 tcatcatgga tgccattgcc atcaacccaa caccgacaga caaaggaaaa cgtctcaaga
    44821 ttttctatgc gacccaagtg gcaaccaaac caccaacctt tgtcatcttt gtcaatgaag
    44881 aagaactcat gcacttttct tacctgcgtt tcttggaaaa tcaaatccgc aaggcctttg
    44941 tttttgaggg aacaccgatt catctcatcg caagaaaacg caaataaaaa agtagaatct
    45001 ggaatgacag ttccggattt ttttgatata ataaaataat agaaaacgct atcaaaagaa
    45061 ggagggtgat gtcggtgatg gaacatttgt ttaaattctt acttttagca ccgtactttt
    45121 attttgataa ctggattgag aaggccaaca gaaatagtaa gttttttcca attttttatt
    45181 atttttactg gttttacatc cccttctatt ctctttttag ccttgcttgg acagttgttt
    45241 cagttctgtt tttcaatacc gtcttgagaa atgtgacaga tatcaagtta tggggcattt
    45301 ggtttctttt tattctgcta gctattggta tgaattggtt aacttattcc tgtttcaaag
    45361 aaatgtttcg cttgagacag gaactaggga agtctaaggg tggaaggcat tgatttatat
    45421 cggtttctat ttgtaggagg tggcttatgg tacctctaaa atcatttatt acacgctatt
    45481 ccaaggttta tattggtaat aacatttaat agaacgaaac taaagaaaac aatttaaaag
    45541 aggaggtttg tgatggaata cttgtttaaa atgataatct tattaccctg tttttacttt
    45601 ttcagctgga ttgaaaaggc aaacagagat agtaagattt tcccaatttt ttactatttt
    45661 tactggattt acatcaccct ctatgctctt tttagccttg cttggacagt tttttcagtt
    45721 ctgtttttca atatcgtctt gagaaatttg acagatatca agttatgggg tatttggcta
    45781 ttattactac ttatcgcttt tgctagtgac tggttagact atatctgttt caaaaaaatg
    45841 cttgacttga gacgggaact agggaagtct aaaggcggaa ggcattgatt tatactcttc
    45901 gaaaatctct tcaaaccacg tcaacgtcgc cttggattat atatgtaact gacttcgtca
    45961 gtcttatcta caacctcaaa gcagtgcttt gagcaacttg cggctagttt cctagtttgc
    46021 tctttgattt tcattgagta ttatattact ttctatttgt aggaggtggc ttatgaagat
    46081 tcctctctta actttggcaa ggcataaatt tgtttatgtc ttgcttactt tgctttttct
    46141 tgctttggtt tatcgtgatg ttttgatgac ttatttcttt tttgatattc atgcgcccga
    46201 tctagctaaa ttcgatggac aagcaattaa aaatgactta ttaaaatcag cattagattt
    46261 tcgtattctc cagttcaatc taggttttta tcaatcattt attattccaa tcatcattgt
    46321 tttgctaggt tttcaatata ttgagctgaa aaataaagtt ttacgattga gtattggaag
    46381 agaagtgagc tatcaagggt taaaaagaaa gttgactttg caagttgcaa gtatcccttg
    46441 tttgatatat ttagtgactg tgctgataat tgcaattata acctatttct ttgggacttt
    46501 ttctcctctt gaatggaatt ctctattttc tgatgggagt ggtttacaaa gactcctaga
    46561 tggagagata aaaagctatt tgttctttac ttgtgtccta ctaatcggta ttttcatcaa
    46621 tgcaatctat tttttacaaa tagttgatta tgtggggaat gtgactcgtt cggcaatcac
    46681 ctatttgatg tttctttggc ttggttctat gctgctctat agtgccttgc cttactatat
    46741 ggttcctatg acgagtttga tgcaagctag ctatggggat gtaagtttga tgaaactctt
    46801 tactccttat atccttcatg ttgtccctta tatggtactt aaaaaatatg aagataatgt
    46861 ttaagaattt taacaatatt tggctaaaga gaaagatcgt tttactactt cgtatagttc
    46921 tgatgatgat tttgataaac tatctattgt caacagcggt tcaaaagcag gatgctgtta
    46981 tctttttcaa gagagaattg atttcaattt tttcctataa tgactattct gaagcgaatt
    47041 tagaaatccc caaactcttg ttaaaccttt cgcttttcat ggtaggatgg ctctctgtca
    47101 ttttacttga aagtgatttg gcagaccatt accatcactt gattcgctat caatcaagct
    47161 cctttttcga ttatacaagg aaacgattgg ttgtcatttc taaatttttt actcaagatt
    47221 tgtttgtctg gtttcttggt ttacttccgc taggaattca tttcaaaaca gtcgcacttt
    47281 tctttttact tgctcagtta atgatgttgt acttactact gtcttatctg atagcactga
    47341 ttagtgcggg cgctggtttt tctttttttc tctatttttt ggcatttgtg ggacaagaat
    47401 ggatgatgga tcatattgta acagtgtatt tagtactctt aagcttatta gttatgttga
    47461 ttgttagtcg cttggaagag aaatttaaga aaggataaac gatgagactt gaaattataa
    47521 atggacagaa aatttatggg aaaagaccta ttttaaatca gttgaatttg gtgtttcaat
    47581 caggaaaaat ttatggactt aaaggtgata atggatctgg caagacggtt cttttaaaga
    47641 tacttgctgg ttatattaag cttgacaaag gaaaagttct tcaagatggt aaagtttacg
    47701 gggtaaaaaa tcattatatt caggatgcag gaattttaat tgaaaaagtc gagtttttat
    47761 ctcatttatc cctgagagaa aatttggaac tgttaaggta tttttcatct aaagttacgg
    47821 aaaaaagaat tgcctattgg attcaatact atgatttaca ggaatttgaa gacgttgaat
    47881 accgtcattt atccttggga acaaagcaaa aaatggcctt gattcaagcc tttatttcct
    47941 ctccttctat actctttctc gatgaaccta tgaatgcttt ggatgagaag agtgtgaggt
    48001 taaccaaaca ggtcatttta tcttacctga aaaaagaaaa tggtctggtt atcctgacgt
    48061 cgcacatatc ggaagatatt tcagaccttt gtacagatgt attagttgtc gaaaatggac
    48121 atatacaata tgtaaaggat atacaatcct aggagatggc ttatggcaca tctaaaatca
    48181 tttattacac gctattccaa ggtttatatt ggtttagttc tgctgatctg gctgtctttc
    48241 ttctttatcc cttgggatag agcgattctg ggggtaagga ttgacatctt catcatgcag
    48301 aaaatcttgc tagcttttgg aattctgtcc attctcatgg ccttgctgtc caagaaagtc
    48361 agtctctttg tttttggact gatttgctgt ctttctcttt ggattaactt atttatcaca
    48421 tttgccattt tgccgatttt tggcaattaa acagtcataa aagtcggaga ggttagcttg
    48481 aaaactaacc tctttttcct tttcaaaatg gggattcttc cttgaaaata atcagtaatt
    48541 gtgctaaaat taaaggaaca ttctaaaata ttcggaattt aaagtaagga aaaacatggc
    48601 taatatttta aaaacaatta tcgaaaatga taaaggagaa atccgtcgtc tggaaaagat
    48661 ggctgacaag gttttcaaat acgaagacca aatggctact ttgactgacg accaactaaa
    48721 agcaaaaaca gttgaattta aggaacgtta tcaaaatgga gaatcactgg attcattgct
    48781 ttacgaagca tttgcggttg tccgtgaagg tgccaaacgt gtcctaggtc tcttccctta
    48841 taaggttcag gtcatggggg ggattgttct tcaccatggt gacgtgccag agatgcgtac
    48901 aggggaaggg aaaaccttga ctgcgaccat gccggtatac ctcaatgccc tttcaggtaa
    48961 aggggttcac gtagttacgg ttaatgaata cctgtcagaa cgtgacgcga ctgagatggg
    49021 tgaattgtac tcttggcttg gtttgtcagt agggattaac ttggctacca aatctccaat
    49081 ggagaaaaaa gaagcctatg agtgtgatat tacttactca actaactcag aaatcggatt
    49141 tgactacctt cgtgacaaca tggtcgttcg cgccgaaaac atggtacaac gtccgcttaa
    49201 ctatgccttg gtcgatgagg ttgactctat cttgattgac gaggctcgta cacctttgat
    49261 tgtatcaggt gccaatgcgg ttgaaaccag tcagttgtat cacatggcag accactatgt
    49321 aaaatctttg aacaaagatg actacatcat cgatgtgcag tctaagacta ttggtttgtc
    49381 tgattcaggg attgacaggg ctgaaagcta cttcaaactt gaaaacctct atgacatcga
    49441 aaacgtggct ttgactcact ttatcgataa cgcccttcgt gccaactaca tcatgcttct
    49501 cgatattgac tatgtggtga gcgaagagca agaaatcttg attgtcgacc aatttacagg
    49561 tcgtaccatg gaaggtcgtc gttattctga tggattgcac caagctattg aagccaaaga
    49621 aggtgtgcca atccaggatg aaaccaagac atctgcctca atcacgtacc aaaacctttt
    49681 ccgtatgtac aagaaattgt ctggtatgac gggtacaggt aagactgagg aagaagaatt
    49741 ccgtgaaatc tacaacattc gtgttattcc aatcccaaca aaccgtcctg ttcaacgtat
    49801 tgaccactca gaccttcttt atgcaagtat cgaatctaag tttaaagcgg ttgtcgaaga
    49861 cgttaaggct cgttaccaaa agggtcaacc tgtcttggtt ggtacagtgg cggttgaaac
    49921 tagtgactac atttctaaga aattggttgc agctggtgtt cctcacgaag tcttgaatgc
    49981 caaaaaccac tatagagaag cccaaatcat catgaatgct ggtcaacgtg gtgccgttac
    50041 catcgcaacc aacatggcgg gtcgtggtac cgacatcaag cttggtgaag gtgttcgtga
    50101 acttggagga ctttgtgtta ttggtacaga acgtcatgaa agtcgtcgta tcgataacca
    50161 gcttcgtgga cgttcaggtc gtcaaggaga tccaggtgag tcacaattct acctatctct
    50221 tgaagatgat ttgatgaaac gttttggttc tgaacgcttg aagggaatct ttgaacgttt
    50281 gaacatgtct gaagaggcga ttgagtctcg catgttgacg cgtcaggttg aagcagctca
    50341 gaaacgtgtc gaaggaaata actacgatac ccgtaaacaa gtccttcaat acgatgatgt
    50401 catgcgtgaa caacgtgaga ttatctatgc tcaacgttac gatgtcatca ctgcagatcg
    50461 tgacttggca cctgaaattc aggctatgat caaacgcacg attgaacgtg tcgttgatgg
    50521 tcatgcgcgt gccaaacaag atgaaaaact agaggcaatt ttgaactttg ctaagtacaa
    50581 cttgcttcct gaagattcta ttacgatgga agacttgtca ggcttgtctg ataaggccat
    50641 caaggaagag cttttccaac gtgccttgaa ggtttacgat agtcaggttt caaaactacg
    50701 cgatgaagaa gcagttaaag aattccaaaa agttttgatt ctacgagtgg tggataacaa
    50761 gtggacagat catatcgatg cccttgatca attgcgtaac gcggttggac ttcgtggcta
    50821 tgctcagaac aaccctgttg ttgagtatca ggcagaaggt ttccgtatgt ttaatgatat
    50881 gattggttcg attgagtttg atgtgacacg cttgatgatg aaagcacaaa ttcatgaaca
    50941 agaaagacca caggcagaac gtcatatcag tacaacagcg actcgcaata tcgctgctca
    51001 ccaagcaagt atgccagaag atttggattt gagccagatt ggacgcaatg aactttgccc
    51061 atgtggttct ggtaagaaat ttaaaaactg tcacggtaaa agacaataaa atgagatagt
    51121 ttagaggcgg atatcttgtg aaaagtaaat ttttactggg tatccgtttg ctttataagg
    51181 agatgagtta tggtatttac agcaaaaagc tctaaaataa atatagaaga agttcgtgcc
    51241 ttgtcaaaat tagaaggtca ggctttggag aggaaatcac agcgcgatca agagctagaa
    51301 gccattatac gtggagaaga tcagcgaatt ctcttggtaa tcgggccatg ctcatctgac
    51361 aacgaagaag ctgtccttga atacgctaag cgtttggcag tcctacaaga agaagtggca
    51421 gatcgtatct ttatggttat gcgtgtttat actgccaaac cccgtaccaa cggagatggc
    51481 tataagggct tgattcacca gcctaacgcg acagaagcgc ctagtcttat caatggaatc
    51541 aaagccgttc gccatcttca ctatcgtgtc atcacagaaa cagggatgac aactgctgat
    51601 gaaatgcttt atcctgaaaa ccttccgctt gtagatgatt tgatttctta catggcagtt
    51661 ggtgcccgtt cagttgaaga ccagcaacac cgctttgtgg caagtggggc aggattttct
    51721 actggtttta aaaatccaac ctctggaaat ctcaatgtca tgtttaatgg gatttatgct
    51781 gctcaaaaca aacaaagttt ccttttctta ggaaaagaag tagaaacaac tgggaacccg
    51841 ctttcacacg ctattcttcg tggtgctctt aatgagtatg gaaaaaatat tcccaactac
    51901 tattatgaca atttaattga taccattgcc caatatgaga aaatgggctt ggaaaatcct
    51961 tttatcatca ttgataccaa tcatgacaat tctggtaagc agtatattga acagatccga
    52021 attgtccgcc agaccttgat taaccgtgct tggaatgaaa aaattaagca gttcgttcgt
    52081 ggttttatga ttgagtctta tctggaagat ggtcgacaaa atgagccaga agtatttggc
    52141 aagtctatca cagacccttg cctgggttgg gataacacag aagctcttgt cagagaaatt
    52201 tacaaaacgt taggagaata agatggcatt tattgaaaaa ggtcaagaaa tcgatatgga
    52261 agtcatcaag gctgaaaccc aattgtctgc ggaagccttg agactcaagg aaagccgtga
    52321 cagggaattg gcagatatta tttcagggga agatgaccgt attctcttgg tgattggtcc
    52381 ttgctcttct gataatgaag aggcggtctt ggaatatgct cgccgtttat ccgccttgca
    52441 aaagaaggta gcggacaaga ttttcatggt catgcgcgtg tatactgcta agcctcgtac
    52501 caatggagac ggctataaag gattggttca ccagccagat acttctaagg ctccaagcct
    52561 gattaacggt ttgcaggctg tgcgccagtt gcattaccgc gtgattacag agactggttt
    52621 gacaacggca gatgagatgc tttatccgtc aaatctgatc ttggtggatg acttggtcag
    52681 ctaccatgcc gttggagctc gttctgtgga agaccaagag caccgctttg tggcttctgg
    52741 gattgatgca ccagtaggga tgaaaaatcc aacctcagga aatttgggtg ttatgtttaa
    52801 cgccatctat gctgctcaaa acaagcaaac cttcctttat catgggcagg aagttgagac
    52861 atcaggtaat cctttggccc atgttatcct ccgtggagca gtcaacgagt atggcaatta
    52921 tatgccgaat tactactatg aaaacctact ccaagccatt gaacgctatg aaaccatggg
    52981 acttgaaaat ccttttatcc tcattgacac caaccatgat aactcaggca agcaatatat
    53041 ggagcagatt cgaattgttc gccagacctt gcagaatcgt gattggaatg agaaaattaa
    53101 aaagacggtt cgaggattta tgattgaatc ttacctagca gatggtcgtc aaaaccaacc
    53161 agagatcttt ggttgctcta ttactgaccc ttgcctaggt tgggaaaata cagaggcctt
    53221 ggtagaagag atttatgtta ccttgacaaa ataagtgaaa aggatggagt tggggaatct
    53281 caactccttt tgatgagaat gatagttgga cacggaattg acatcgaaga attggcttcg
    53341 atagaaagcg cagttacacg acatgaagga tttgctaagc gtgtactgac cgctcaggaa
    53401 atggagcgct tcaccagtct caaaggacgc aggcaaatag aatatttagc tggtcgctgg
    53461 tcggctaagg aggccttttc caaggctatg ggaacgggca ttagcaagct cggttttcag
    53521 gatttggaag tattgaacaa tgaacgtggg gcgccttatt ttagtcaggc accattttca
    53581 ggaaagattt ggctgtctat cagccacacc gatcagtttg tgacagccag tgtcattttg
    53641 gaggaaaatc atgaaagcta gtccacatag accaaccaag gctctgattc atctgggagc
    53701 tattcgacaa aatattcagc aaatgggggc tcatatccct caaggaacgc tcaagttggc
    53761 tgtggttaag gccaatgctt atggtcatgg agctgttgcc gttgccaagg caattcaaga
    53821 tgatgttgat ggcttttgcg tttccaatat cgatgaagcc attgaactca gacaagctgg
    53881 actcagcaag ccaatcctca ttttaggagt ttctgaaatc gaagctgttg ctctagctaa
    53941 agaatatgac ttcaccttga cagtggctgg actggagtgg attcaagcac tcttagataa
    54001 ggaagtggac ctaactggat tgacagtcca cctcaagatt gattcaggga tgggacggat
    54061 tggttttaga gaggcaagtg aggttgagca ggctcaagat ttgctccaac aacacggtgt
    54121 tcgtgttgaa ggaatcttta cccactttgc tactgctgat gaggaatcag atgactattt
    54181 taatgcccag ttagaacggt ttaaaactat tttagctagt atgaaggaag ttccagagct
    54241 ggttcatgct agcaattctg caacgactct ttggcatgta gagactattt tcaatgcggt
    54301 tcgtatggga gatgccatgt atggtctcaa tccaagtgga gcggtcttgg ctttgcctta
    54361 tgatttgata ccggccttga ccttggagtc tgctctggtt catatcaaga cagttccagc
    54421 tggtgcttgc atgggctatg gagcaactta tcaaacggat agcgagcaag tcatcgcgac
    54481 cgtgccaatc gggtatgcag atggatggac aagagacatg caaaatttct ctgtcttggt
    54541 agatggccaa gcttgcccaa ttgtcggcag ggtttcgatg gaccaaatca ctattcgatt
    54601 gcctaagcct tacccactcg gaaccaaggt aaccttgatt ggctccaatg gggataagga
    54661 aatcactgca actcaggtag cgacctaccg cgtaaccatt aactatgagg tggtttgcct
    54721 cctcagcgac cgtattccga gagaatatta ttagaaaaga aaggagtgga gcatgaatct
    54781 acatcaaccc ttgcatgtct tgcctggtgt gggaccaaag tcagcagaaa aatacgccaa
    54841 actaggaatt gaaaacttgc aagatctctt gctctacttt cctttccgtt atgaagactt
    54901 caaaaccaag caggtgctgg aactagaaga cggtgagaag gcagttcttt ctggtcaggt
    54961 agtgactcct gctagtgtcc agtattatgg tttcaagcgc aatcgcctgc gttttagtct
    55021 caagcaggga gaggtcgttt ttgcggtgaa tttctttaac cagccctatc tggctgataa
    55081 aatagagttg ggagcaaccc ttgctgtctt tggaaaatgg gaccgcgcta aggctagtct
    55141 gactgggatg aaggttctgg ctcaggtaga agatgacctc cagcctgtct atcgtctggc
    55201 tcagggaatc agtcaggcca gtctggtcaa ggtcatcaag acggcttttg atcagggact
    55261 ggacctcttg atagaagaaa atctgcccca gtctttacta gacaaataca aactcatgtc
    55321 ccgttgtcag gcagtccgag ctatgcattt tccaaaggat ttggcagaat acaagcaggc
    55381 tcttcgccgt atcaagtttg aggaactctt ttatttccaa atgcagttgc agatgctcaa
    55441 gtctgaaaat agagttcagg gaagtggtct ggttctgaat tggtctcagg aaaaagtgac
    55501 agcagttaaa gcaagtcttc cttttgccct gacccaagct caggaaaaga gtttgcagga
    55561 aattttaact gatatgaagt ccgaccacta catgaatcgt ctcctacaag gagatgtggg
    55621 gagcggaaaa acggtagtcg ctggcttggc catgtttgcg gcagtgacag caggttatca
    55681 ggctgcccta atggtaccaa cagaaatcct cgcagagcaa cactttgaga gtttacagaa
    55741 cctttttccc aatttgaaac tggctctctt gacaggttcc ttgaaagctg cagaaaagag
    55801 agaggtcttg gagaccattg ccaagggtga ggctgatttg attataggaa ctcacgctct
    55861 gatacaagat ggggtggagt atgctcgtct tggtttgatt attatcgatg agcagcaccg
    55921 ttttggtgtg gggcaaaggc gtattttacg ggaaaaaggc gacaatccag atgtcctcat
    55981 gatgacggcg actcccattc cacggacgct tgccatcaca gcctttggag atatggatgt
    56041 ttccattatc gaccagatgc cagcaggtcg gaagcctatt gtgacgcgct ggatcaaaca
    56101 tgagcaacta cctcaggtct tgacttggtt agagggggaa attcaaaaag gttcccaagc
    56161 ctatgtcatc tctcctttga ttgaagaatc agaagctcta gatttgaaaa atgccattgc
    56221 cttatcagag gagttgacga ctcattttgc aggcaaggca gaggtggctc ttctacatgg
    56281 taggatgaag agtgacgaaa aagaccagat catgcaggat ttcaaggaga gaaagacgga
    56341 tattctggtt tcgacgacgg ttattgaggt tggggtcaat gttcccaatg cgactgtcat
    56401 gattatcatg gatgccgatc gcttcggtct cagtcaactt caccagctta gaggtcgtgt
    56461 cggtcggggg gacaagcagt cctacgctgt tctcgttgcc aatcccaaga cggattctgg
    56521 gaaagaccgc atgcgcatca tgacagaaac gaccaatgga tttgtccttg cggaggaaga
    56581 tttgaaaatg cgtggttctg gtgagatttt tggaaccaga cagtcaggac ttccagagtt
    56641 ccaagtggct gatattatcg aagattttcc gattttagaa gaagcaagaa aggttgctag
    56701 ctacattagt tctatagaaa cttggcaaga agatccagag tggcgcatga ttgcccttca
    56761 tctggaaaag aaagaacatc tggattaagc tttctctaag gaaaacttaa gctagttttt
    56821 agatttggct cttatactaa agtcatcaaa aagaaacgag gactctcata tgacagtaac
    56881 gattaaagta aattaccaaa ccactttcca aaagaaggaa gca
//
LOCUS       DAVKUR010000007        51320 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKUR010000007 DAVKUR010000000
VERSION     DAVKUR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.007"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            176..652
                     /locus_tag="VW749_000504"
     CDS             176..652
                     /locus_tag="VW749_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0174596.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            690..995
                     /locus_tag="VW749_000505"
     CDS             690..995
                     /locus_tag="VW749_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0174597.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            1043..2518
                     /locus_tag="VW749_000506"
     CDS             1043..2518
                     /locus_tag="VW749_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0174598.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNTAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2541..2618
                     /locus_tag="VW749_000507"
                     /pseudo
     CDS             2541..2618
                     /locus_tag="VW749_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2868..9569
                     /locus_tag="VW749_000508"
     CDS             2868..9569
                     /locus_tag="VW749_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0174599.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNIVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLID
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVTQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPSTGSAASQAAVAAGLTLLGLSAGLVVTKGKKED"
     gene            complement(9817..10673)
                     /locus_tag="VW749_000509"
                     /pseudo
     CDS             complement(9817..10673)
                     /locus_tag="VW749_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10883..11242)
                     /locus_tag="VW749_000510"
     CDS             complement(10883..11242)
                     /locus_tag="VW749_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0174600.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            11265..11843
                     /locus_tag="VW749_000511"
     CDS             11265..11843
                     /locus_tag="VW749_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEV0174601.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVMKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVVRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            11844..12290
                     /locus_tag="VW749_000512"
     CDS             11844..12290
                     /locus_tag="VW749_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEV0174602.1"
                     /translation="METVKRLRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTNNDI
                     QGIKLHLLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAP
                     RDMLLGLMWSLNKWEALNSIEMEMRRRGSVQGCKAVKQEFENEKTT"
     gene            12274..12831
                     /locus_tag="VW749_000513"
     CDS             12274..12831
                     /locus_tag="VW749_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0174603.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12824..13078
                     /locus_tag="VW749_000514"
     CDS             12824..13078
                     /locus_tag="VW749_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174604.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            13090..15144
                     /locus_tag="VW749_000515"
     CDS             13090..15144
                     /locus_tag="VW749_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0174605.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            15323..16183
                     /locus_tag="VW749_000516"
     CDS             15323..16183
                     /locus_tag="VW749_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0174606.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILIMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            16394..17104
                     /gene="ccdA2"
                     /locus_tag="VW749_000517"
     CDS             16394..17104
                     /gene="ccdA2"
                     /locus_tag="VW749_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0174607.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            17124..17690
                     /locus_tag="VW749_000518"
     CDS             17124..17690
                     /locus_tag="VW749_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0174608.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17701..18813
                     /gene="msrB"
                     /locus_tag="VW749_000519"
     CDS             17701..18813
                     /gene="msrB"
                     /locus_tag="VW749_000519"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0174609.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            19171..19908
                     /locus_tag="VW749_000520"
     CDS             19171..19908
                     /locus_tag="VW749_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0174610.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            19905..21596
                     /locus_tag="VW749_000521"
     CDS             19905..21596
                     /locus_tag="VW749_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0174611.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            21712..22275
                     /locus_tag="VW749_000522"
     CDS             21712..22275
                     /locus_tag="VW749_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0174612.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            22297..28239
                     /locus_tag="VW749_000523"
     CDS             22297..28239
                     /locus_tag="VW749_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0174613.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEDTQPEVVETKDEAANQP
                     VEEPKVETPAVEKQTEPTEEPKVEQVGEPVEPREDEKAPVSPEKQPEAPEEEKTAEET
                     PKQEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASE
                     PVKQPEVNSETKAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQLKIAQGK
                     TETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVDKTALGSA
                     IDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELS
                     EKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVKDFVLTEENLKT
                     NHLTALFEKLDYYKEYTLSTDMVYNRGNDDETESISEELIQLNLKKLELKDIQTVSLM
                     KFENGQESQVTHLSDKPTDLSKLYLKVTSSTSKDAVLAVSSIEEEIVENKKIFKIHAD
                     TPELVVRKKDGSLSKGFDYYMERVIPHDGDIYYDFKDLISAMTSNPTGTFILGRDISS
                     RNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIFDLEYPLFDTIKSGVVKDIDFKHVNM
                     VFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEGRDHVAGLVNNLEGNSEIENISFT
                     GKIKSKGGNSITAGIAGRNILSRVKRAYVNANIEVLGSTNSSMLVAVNGTTLNASGGW
                     GAWGRLTESVAKGTLEIKRSGQAGGVTATVWPYGAIDKVVSYAKVTKGKELFGSDGDL
                     NNNWFMQKINNIFGVQGISSGDSGNDSKFKRISEEEAKQKVASYNITAPNLMSDSSLL
                     VDRLNESWKNTDQFESIQDYQSQNQLIYQNLTKFTPYYNKEFIVHEGNALTPEQEILK
                     TKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQKRYKVTSTGKFSITNLPEYQVEDL
                     NVVYTSEHIVHPLDSSLINNLVEELKKVELYTESTYQVLGIDKDNANKLNRTKRLFLD
                     ESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAALRQKIMDNKTAILLALTYINRYY
                     DVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGSSGENRLKGSENAETFKQLFASET
                     KQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQFEERPSLVEEIKDAKYRVYDNLT
                     APYYQGYILPLLTLKNTHLAILSNYSTMTFVSREKRPNWKNEDFDKWVKYVATAHRNH
                     VDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEWVDQNAVDRKGRDYAPAREFFNLV
                     GGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYGISVFTHELTHVNDTWIYLGGYGR
                     RENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFERKNDGDLIYNASPTQFENRKELDS
                     YMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKVEPKVVSQTAQYDTVRQLTAEEKE
                     KLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSYIAIDYMTGIYGGGKNSVGSPGAL
                     MFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEGHAGLSDNFIISKISKGEFLTMEA
                     FKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQEGFKQAVERDLKKNQLDERETRN
                     FKFQVFRQLLQQTDSFKTSIFR"
     gene            28300..30021
                     /gene="pabB"
                     /locus_tag="VW749_000524"
     CDS             28300..30021
                     /gene="pabB"
                     /locus_tag="VW749_000524"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0174614.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            30022..30639
                     /locus_tag="VW749_000525"
     CDS             30022..30639
                     /locus_tag="VW749_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0174615.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGRKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            30689..31567
                     /locus_tag="VW749_000526"
     CDS             30689..31567
                     /locus_tag="VW749_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0174616.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEREPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYARNAWQGN
                     YYLKSDGKMAKGEWVYDATYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGG
                     RYYVGADGVWKEGQASTVSSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFD
                     KFSNDAAQYAIDHLDD"
     gene            31694..32653
                     /locus_tag="VW749_000527"
     CDS             31694..32653
                     /locus_tag="VW749_000527"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0174617.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            32750..33589
                     /locus_tag="VW749_000528"
     CDS             32750..33589
                     /locus_tag="VW749_000528"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0174618.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(33637..33807)
                     /locus_tag="VW749_000529"
     CDS             complement(33637..33807)
                     /locus_tag="VW749_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0174619.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33928..34812
                     /gene="miaA"
                     /locus_tag="VW749_000530"
     CDS             33928..34812
                     /gene="miaA"
                     /locus_tag="VW749_000530"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0174620.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            34805..36043
                     /gene="hflX"
                     /locus_tag="VW749_000531"
     CDS             34805..36043
                     /gene="hflX"
                     /locus_tag="VW749_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0174621.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            36036..36659
                     /locus_tag="VW749_000532"
     CDS             36036..36659
                     /locus_tag="VW749_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0174622.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            36674..37603
                     /locus_tag="VW749_000533"
     CDS             36674..37603
                     /locus_tag="VW749_000533"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0174623.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            37624..38379
                     /locus_tag="VW749_000534"
     CDS             37624..38379
                     /locus_tag="VW749_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0174624.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(38433..39341)
                     /locus_tag="VW749_000535"
     CDS             complement(38433..39341)
                     /locus_tag="VW749_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0174625.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            39405..39674
                     /locus_tag="VW749_000536"
     CDS             39405..39674
                     /locus_tag="VW749_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0174626.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39674..40054
                     /locus_tag="VW749_000537"
     CDS             39674..40054
                     /locus_tag="VW749_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0174627.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            40172..40369
                     /locus_tag="VW749_000538"
     CDS             40172..40369
                     /locus_tag="VW749_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174628.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
     gene            complement(40409..41134)
                     /locus_tag="VW749_000539"
     CDS             complement(40409..41134)
                     /locus_tag="VW749_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0174629.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            41296..43137
                     /gene="typA"
                     /locus_tag="VW749_000540"
     CDS             41296..43137
                     /gene="typA"
                     /locus_tag="VW749_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0174630.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            43157..43411
                     /locus_tag="VW749_000541"
     CDS             43157..43411
                     /locus_tag="VW749_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0174631.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            43775..44074
                     /locus_tag="VW749_000542"
                     /pseudo
     CDS             43775..44074
                     /locus_tag="VW749_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            44145..46166
                     /locus_tag="VW749_000543"
     CDS             44145..46166
                     /locus_tag="VW749_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0174632.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            46168..46809
                     /locus_tag="VW749_000544"
     CDS             46168..46809
                     /locus_tag="VW749_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174633.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            46913..48265
                     /locus_tag="VW749_000545"
     CDS             46913..48265
                     /locus_tag="VW749_000545"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0174634.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            48269..49327
                     /locus_tag="VW749_000546"
     CDS             48269..49327
                     /locus_tag="VW749_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0174635.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            49337..50557
                     /gene="divIB"
                     /locus_tag="VW749_000547"
     CDS             49337..50557
                     /gene="divIB"
                     /locus_tag="VW749_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0174636.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
BASE COUNT        15771 a         9366 c        11402 g        14781 t
ORIGIN      
        1 ttagaacaga aaaaatactt ggagtatttg tttgtgtgtt tatttttata taacaaacta
       61 taaacaaaac aaaaatataa aaaaagagac aaaaaaagaa cagaaagcaa ttgacaacgg
      121 tttcatatag tgttatactt atggcataaa gttaatggaa agaagggaaa aacttatggt
      181 attagattat ttctttgaca aaaaccttgt gttttgctta gaagcggata atcaagaaca
      241 actctttgat caggttgcaa ctttattgga agaacgagaa attgtcactc caacttatcg
      301 tgaagccttg atcacgcgtg aaaagtcatt tccaactggt ttagatatgg aatttctagg
      361 aaaggacttg ccaaatgtag cgattcctca tacagatatt gttcataatc tagctgagaa
      421 agtggtggtt gttcgattag aaaaaccagt aacttttcac aatatgatag ctcctgataa
      481 ggaagtagaa gtatccctac tcttctttat tattaacaat tcaagttcaa gtcaaacaaa
      541 tattctggct cagttgatgg actttttcac aggaaatgga catcttgaag acctatcaaa
      601 aatttccgaa ccagaaaaac tttatgctta cattgctgaa gcaaccgctt aatcttgtct
      661 attaaaaaat aaaatcggag gaaatccaaa tgattaaaat tcttgctgcc tgcggtgcag
      721 gtgttaactc aagtcaccaa attaaaagtg ctctagaaga agaactttca aaccgtggtt
      781 atgatgttca ctgtgatgca gtcatggtga aagatgtaaa cgaagacctt atgaaaggtt
      841 acgatatctt tacaccaatc gctgcaacag accttggttt tgaaccaggt atcccagtta
      901 tcgaagctgg gccaatctta ttccgtatcc cagcaatgag cgctccagta tttgacaata
      961 ttgaagcagc tattaaagaa cacggattaa gctaattcta atttgttaac attcatataa
     1021 cataaaaaag ggaggaactg ttatggatgc aatctttgac ctaatcggaa aggttttcaa
     1081 tcccatttta gaaatgggtg gacctgtcat catgttaatc attttgacag tattggcttt
     1141 actttttgga gtgaaattct ccaaagcgct tgaaggtggt atcaaacttg ccatcgctct
     1201 tacaggtatc ggtgctatca tcggtatgct aaacactgct ttctcagcat cactagcaaa
     1261 attcgttgaa aacactggta tccaattgag tattaccgac gttggttggg caccacttgc
     1321 tacaatcact tggggttctg cttggacact atacttcttg ctcatcatgt tgattgtcaa
     1381 catagtgatg ctagctatga agaaaacaga tacacttgat gtcgatatct ttgatatctg
     1441 gcacttgtct atcacaggtc tcttgattaa atggtatgct gataacaatg gtgtgagtca
     1501 aggggtttca ctctttattg ctacagcagc tatcgtcctt gtcggtgtgt tgaaaattat
     1561 caactctgac ttgatgaaac ctacatttga tgaccttctt aacgccccaa gttcatcacc
     1621 aatgacatca actcacatga actacatgat gaacccagtt atcatggttt tggataagat
     1681 ttttgaaaaa ttcttcccag gccttgataa atatgacttt gatgctgcta aattgaacaa
     1741 gaaaatcggt ttctggggat ctaaattctt catcggtttc atccttggta tcgttatcgg
     1801 tattatggga actccacatc caattgcagg tgttgcagat gcagataaat ggcgtcttgt
     1861 tatcaaagga tggttgtctc ttggtttgac tgccggtgta tctttggaac tcttctcact
     1921 tatcggttca tggttcatcg cagccgtaga accactatca caaggtatta caaacgttgc
     1981 tactaaacgt cttcaaggac gtaaattcaa tatcggtctt gactggccat tcatcgctgg
     2041 tcgtgctgaa atctgggctt gtgccaacgt acttgcacca atcatgttga ttgaagcagt
     2101 gcttctttca aaagttggaa atggtatctt gccacttgca ggtatcatcg ctatgggtgt
     2161 tactccagct ctcttggttg taactcgtgg taaattgctc cgtatgatta tcttcggaac
     2221 actcttgttg ccactcttcc ttctttcagg tacacttatt gcaccatttg caacagaact
     2281 tgctaaaggt gtaggtgcct tcccagaagg tgtgagccaa actcaattga ttactcactc
     2341 tactcttgaa ggaccaatcg aaaaacttct tggttggaca attggtaaca ctacaactgg
     2401 tgatatcaaa gcaatccttg gtgcagtagt cttccttgta ttctatatcg gtatctttgc
     2461 ttggtacaga aaacaaatga tcaaacgtaa cgaagagtac gcagcaaaag caaaataatg
     2521 cgctcctata aaatataaac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
     2581 gttgctcaaa acacagtttt gaggttgtag ataagactga cgaagtcagc tcaaaacatg
     2641 gttttgaggt tgtagatgaa actgacgaag tcagctcaaa acatggtttt gaggttgtag
     2701 atgaaactga cgaagtcagt aatcatatct acggcaaggc gacactgacg aagtttgaat
     2761 tggattttcg cagagtgtaa attgttgaaa ctaggttgtc ataccatgta taccacttgg
     2821 gctttggtag tagctaactg cactaaatat aatataagga gggttttatg gggaaaggcc
     2881 attggaatcg gaaaagagtt tatagcattc gtaagtttgc tgtgggagct tgctcagtaa
     2941 tgattgggac ttgtgcagtt ttattaggag gaaatatagc tggagaatct gtagtttatg
     3001 cggatgaaac acttattact catactgctg agaaacctaa agaggaaaaa atgatagtag
     3061 aagaaaaggc tgataaagct ttggaaacta aaaatatagt tgaaaggaca gaacaaagtg
     3121 aacctagttc aactgaggct attgcatctg agaagaaaga agatgaagcc gtaactccaa
     3181 aagaggaaaa agtgtctgct aaaccggaag aaaaagctcc aaggatagaa tcacaagctt
     3241 caaatcaaga aaaaccgctc aaggaagatg ctaaagctgt aacaaatgaa gaagtgaatc
     3301 aaatgattga agacaggaaa gtggatttta atcaaaattg gtactttaaa ctcaatgcaa
     3361 attctaagga agccattaaa cctgatgcag acgtatctac gtggaaaaaa ttagatttac
     3421 cgtatgactg gagtatcttt aacgatttcg atcatgaatc tcctgcacaa aatgaaggtg
     3481 gacagctcaa cggtggggaa gcttggtatc gcaagacttt caaactagat gaaaaagacc
     3541 tcaagaaaaa tgttcgcctt acttttgatg gcgtctacat ggattctcaa gtttatgtca
     3601 atggtcagtt agtggggcat tatccaaatg gttataacca gttctcatat gatatcacca
     3661 aataccttca aaaagatggt cgtgagaatg tgattgctgt ccatgcagtc aacaaacagc
     3721 caagtagccg ttggtattca ggaagtggta tctatcgtga tgtgacttta caagtgacag
     3781 ataaggtgca tgttgagaaa aatgggacaa ctattttaac accaaaactt gaagaacaac
     3841 aacatggcaa ggttgaaact catgtgacca gcaaaatcgt caatacggac gacaaagacc
     3901 atgaacttgt agccgaatat caaatcgttg aacgaggtgg tcatgctgta acaggcttag
     3961 ttcgtacagc gagtcgtacc ttaaaagcac atgaatcaac aagcctagat gcgattttag
     4021 aagttgaaag accaaaactc tggactgttt taaatgacaa acctgccttg tacgaattga
     4081 ttacgcgtgt ttaccgtgac ggtcaattgg ttgatgctaa gaaggatttg tttggttacc
     4141 gttactatca ctggactcca aatgaaggtt tctctttgaa tggtgaacgt attaaattcc
     4201 atggagtatc cttgcaccac gaccatgggg cgcttggagc agaagaaaac tataaagcag
     4261 aatatcgccg tctcaaacaa atgaaggaga tgggagttaa ctccatccgt acaacccaca
     4321 accctgctag tgagcaaacc ttgcaaatcg cagcagaact aggtttactc gttcaggaag
     4381 aggcctttga tacgtggtat ggtggcaaga aaccttatga ctatggacgt ttctttgaaa
     4441 aagatgccac tcacccagaa gctcgaaaag gtgaaaaatg gtctgatttt gacctacgta
     4501 ccatggtcga aagaggcaaa aacaaccctg ctatcttcat gtggtcaatt ggtaatgaaa
     4561 taggtgaagc taatggtgat gcccactctt tagcaactgt taaacgtttg gttaaggtta
     4621 tcaaggatgt tgataagact cgctatgtta ccatgggagc agataaattc cgtttcggta
     4681 atggtagcgg agggcatgag aaaattgctg atgaactcga tgctgttgga tttaactatt
     4741 ctgaagataa ttacaaagcc cttagagcta agcatccaaa atggttgatt tatggatcag
     4801 aaacatcttc agctacccgt acacgtggaa gttactatcg ccctgaacgt gaattgaaac
     4861 atagcaatgg acctgagcgt aattatgaac agtcagatta tggaaatgat cgtgtgggtt
     4921 gggggaaaac agcaaccgct tcatggactt ttgaccgtga caacgctggc tatgctggac
     4981 agtttatctg gacaggtacg gactatattg gtgaacctac accatggcac aaccaaaatc
     5041 aaactcctgt taagagctct tactttggta tcgtagatac agccggcatt ccaaaacatg
     5101 acttctatct ctaccaaagc caatgggttt ctgttaagaa gaaaccgatg gtacaccttc
     5161 ttcctcactg gaactgggaa aacaaagaat tagcatccaa agtagctgac tcagaaggta
     5221 agattccagt tcgtgcttat tcgaatgctt ctagtgtaga attgttcttg aatggaaaat
     5281 ctcttggtct taagactttc aataaaaaac aaaccagcga tgggcggact taccaagaag
     5341 gtgcaaatgc taatgaactt tatcttgaat ggaaagttgc ctatcaacca ggtaccttgg
     5401 aagcaattgc tcgtgatgaa tctggcaagg aaattgctcg agataagatt acgactgctg
     5461 gtaagccagc ggcagttcgt cttattaagg aagaccatgc gattgcagca gatggaaaag
     5521 acttgactta catctactat gaaattgttg acagccaggg gaatgtggtt ccaactgcta
     5581 ataatctggt tcgcttccaa ttgcatggcc aaggtcaact ggtcggtgta gataacggag
     5641 aacaagccag ccgtgaacgc tataaggcgc aagcagatgg ttcttggatt cgtaaagcat
     5701 ttaatggtaa aggtgttgcc attgtcaaat caactgaaca agcagggaaa ttcaccctga
     5761 ctgcccactc tgatctcttg aaatcgaacc aagtcactgt ctttactggt aagaaagaag
     5821 gacaagagaa gactgttttg gggacagaag tgccaaaagt acagaccatt attggagagg
     5881 cacctgaaat gcctaccact gttccgtttg tatacagtga tggtagccgt gcagaacgtc
     5941 ctgtaacctg gtcttcagta gatgtgagca agcctggtat tgtaacggtg aaaggtatgg
     6001 ctgacggacg agaagtagaa gctcgtgtag aagtgattgc tcttaaatca gagctaccag
     6061 ttgtgaaacg tattgctcca aatactgact tgaattctgt agacaaatct gtttcctatg
     6121 ttttgattga tggaagtgtt gaagagtatg aagtggacaa gtgggagatt gccgaagaag
     6181 ataaagctaa gttagcaatt ccaggttctc gtattcaagc gaccggttat ttagaaggtc
     6241 aaccaattca tgcaaccctt gtggtagaag aaggcaatcc tgcggcacct gcagtaccaa
     6301 ctgtaacggt tggtggtgag gcagtaacag gtcttactag tcaaaaacca atgcaatacc
     6361 gcactcttgc ttatggagct aagttgccag aagtcacagc aagtgctaaa aatgcagctg
     6421 ttacagttct tcaagcaagc gcagcaaacg gcatgcgtgc gagcatcttt attcagccta
     6481 aagatggtgg ccctcttcaa acctatgcaa ttcaattcct tgaagaagcg ccaaaaattg
     6541 ctcacttgag cttgcaagtg gaaaaagctg acagtctcaa agaagaccaa actgtcaaat
     6601 tgtcggttcg agctcactat caagatggaa cgcaagctgt attaccagct gataaagtaa
     6661 ccttctctac aagtggtgaa ggggaagtcg caattcgtaa aggaatgctt gagttgcata
     6721 agccaggagc agtcactctg aacgctgaat atgagggagc taaagaccaa gttgaactca
     6781 ctatccaagc caatactgag aagaagattg cgcaatccat ccgtcctgta aatgtagtga
     6841 cagatttgca tcaggaacca agtcttccag caacagtaac agttgagtat gacaaaggtt
     6901 tccctaaaac tcataaagtc acttggcaag ctattccgaa agaaaaacta gactcctatc
     6961 aaacatttga agtactaggt aaagttgaag gaattgacct tgaagcgcgt gcaaaagtct
     7021 ctgtagaagg tatcgtttca gttgaagaag tcagtgtgac aactccaatc gcagaagcac
     7081 cacaattacc agaaagtgtt cggacatatg attcaaatgg tcacgtttca tcagctaagg
     7141 ttgcatggga tgcgattcgt ccagagcaat acgctaagga aggtgtcttt acagttaatg
     7201 gtcgcttaga aggtacgcaa ttaacaacta aacttcatgt tcgcgtatct gctcaaactg
     7261 agcaaggtgc aaacatttct gaccaatgga ccggttcaga attgccactt gcctttgctt
     7321 cagactcaaa tccaagcgac ccagtttcaa atgttaatga caagctcatt tcctacaata
     7381 accaaccagc caatcgttgg acaaactgga atcgtactaa tccagaagct tcagtcggtg
     7441 ttctgtttgg agattcaggt atcttgagca aacgctccgt tgataatcta agtgtcggat
     7501 tccatgaaga ccatggagtt ggtgtaccga agtcttatgt gattgagtat tatgttggta
     7561 agactgtccc aacagctcct aaaaacccta gttttgttgg taatgaggac catgtcttta
     7621 atgattctgc caactggaaa ccagttacta atctaaaagc ccctgctcaa ctcaaggctg
     7681 gagaaatgaa ccactttagc tttgataaag ttgaaaccta tgctgttcgt attcgcatgg
     7741 ttaaagcaga taacaagcgt ggaacgtcta tcacagaggt acaaatcttt gcgaaacaag
     7801 ttgcggcagc caagcaagga caaacaagaa tccaagttga cggcaaagac ttagcaaact
     7861 tcaaccctga tttgacagac tactaccttg agtctgtaga tggaaaagtt ccggcagtca
     7921 cagcaagtgt tagcaacaat ggtctcgcta ccgtcgttcc aagcgttcgt gaaggtgagc
     7981 cagttcgtgt catcgcgaaa gctgaaaatg gcgacatctt aggagaatac cgtctgcact
     8041 tcactaagga taagagctta ctttctcata aaccagttgc tgcggttaaa caagctcgct
     8101 tgctacaagt aggtcaagca cttgaattgc cgactaaggt tccagtttac ttcacaggta
     8161 aagacggcta cgaaacaaaa gacctgacag ttgaatggga agaagttcca gcggaaaatc
     8221 tgacaaaagc aggtcaattt actgttcgag gccgtgtcct tggtagtaac cttgttgctg
     8281 agatcactgt acgagtgaca gacaaacttg gtgagactct ttcagataac cctaactatg
     8341 atgaaaacag taaccaggcc tttgcttcag caaccaatga tattgacaaa aactctcatg
     8401 accgcgttga ctatctcaat gacggagatc attcagaaaa tcgtcgttgg acaaactggt
     8461 caccaacacc atcttctaat ccagaagtat cagcgggtgt gattttccgt gaaaatggta
     8521 agattgtaga acggactgtt acacaaggaa aagttcagtt ctttgcagat agtggtacgg
     8581 atgcaccatc taaactcgtt ttagaacgct atgtcggtcc agagtttgaa gtgccaacct
     8641 actattcaaa ctaccaagcc tacgacgcag accatccatt caacaatcca gaaaattggg
     8701 aagctgttcc ttatcgtgcg gataaagaca ttgcagctgg tgatgaaatc aacgtaacat
     8761 ttaaagctat caaagccaaa gctatgagat ggcgtatgga gcgtaaagca gataagagcg
     8821 gtgttgcgat gattgagatg accttccttg caccaagtga attgcctcaa gaaagcactc
     8881 aatcaaagat tcttgtagat ggaaaagaac ttgctgattt cgctgaaaat cgtcaagact
     8941 atcaaattac ctataaaggt caacggccaa aagtctcagt tgaagaaaac aatcaagtag
     9001 cttcaactgt ggtagatagt ggagaagata gctttccagt acttgttcgc ctcgtttcag
     9061 aaagtggaaa acaagtcaag gaataccgta tccacttgac taaggaaaaa ccagtttctg
     9121 agaagacagt tgctgctgta caagaagatc ttccaaaaat cgaatttgtt gaaaaagatt
     9181 tggcatacaa gacagttgag aaaaaagatt caacactgta tctaggtgaa actcgtgtag
     9241 aacaagaagg aaaagttgga aaagaacgta tctttacagc gattaatcct gatggaagta
     9301 aggaagaaaa actccgtgaa gtggtagaag ttccgacaga ccgcatcgtc ttggttggaa
     9361 ccaaaccagt agctcaagaa gctaaaaaac cacaagtgtc agaaaaagca gatacaaaac
     9421 caattgattc aagtgaagct agtcaaacta ataaagccca gttaccaagt acaggtagtg
     9481 cggcaagcca agcagcagta gcagcaggtt taactcttct aggtttgagt gcaggattag
     9541 tagttactaa aggtaaaaaa gaagactaga aattttgata ccttctttat cattaaagac
     9601 caaagaaaaa ctcttgtcct aaatagaaga taaagagcct gagacaaaat agttctcaac
     9661 cacaaaaaag ctagatattt ccaattgtgg aactctagct ttttaatttt gagtcattct
     9721 cttattgtat agtagattga aactagaata gtacactttt acttctaaaa cattgttaga
     9781 aatcgatttg attgtcctta tcgatttgtc ctgttcttat ttcattttac tatattttag
     9841 gaggttattg gccataagta ccaatcccat gtcaattctc acttgacgct tccctctcag
     9901 attacatctc ttgtaaccca aagaagcctt tatctgccca aagacaggtt ccacatcaat
     9961 cttgcgttga gcgaaaatct gtctaccttg gggagataaa agcgcctgac attctttagc
    10021 tttcaagttt tgatagcgtt cgttcatata cagtcccttt tgaggggctg attcaggttc
    10081 gtcggcgtag taaaccttga tttcttgttg aaagtctgtc tgtgttttct gatatttggt
    10141 atggtgaaaa cgataatacc agccatcagg atgtgtgtag ctatcctcct tgtcattata
    10201 gtgccaattc gctaagtttt tagctgactc tttataccct ctcttttgtt tcttatcaaa
    10261 catggcatat ttaatcagaa ggggagtgat ttcttcttga aaatagacct gtatctgttc
    10321 ttgaagtttg gcggagaatt tctctgtcgt tttcttccac acaaaactat acttgttggc
    10381 attggcttca atcttagttc tgtcaataaa caaacaatct aaggtcacta actcttccat
    10441 ttttcaattt ttcgaccaga gaaaatccct tgtgaatagg caaatagaag agtagataca
    10501 agcattttag ggtgataaga cgggcgatca aaggcatgat aggaggtgta gaagtgacgt
    10561 tcctccaagg tattcaccac tttttcaata gtaaaaacga gatgatcttg tggtaagaag
    10621 gaactgattt ctagtggtaa agttgtttga tttgtgttat agtgaatatg catgggatag
    10681 cctttctaaa tggtttattg ggcaattcta ttttaccaag actatcgtaa ccatgcaaaa
    10741 aagcaacggc aaatccgttg cctttttgga tataagagac tattgtccca gactcttttc
    10801 tttgtataaa attgtatagt gttattgtct atactatttt gtagagaaag caaaaatccc
    10861 tagaaaatgc ttagggattc gactatttca ttaagaacaa ttcaacaatc atttctatat
    10921 acatgataag ggttaataag aatcctgcac gccagaagaa tttgataaat ttaggatagt
    10981 aaaagctgcg ttttttcaaa aggaagaaaa agacgagaat aatggctagg atcgagaggg
    11041 ctagccccag tctagggagg aaattatggg taaaggtttt agctgtaatc aagtaatact
    11101 caaataccaa gactggaaaa gccaaatccg caaagtttcg tcctagtttt tttaatctaa
    11161 aaagtttggt taggataatg cagacgacta aggtcagtat caataataaa atagatgcta
    11221 atttcattaa aatcataccc atattgtatc ataaaaaaag gctaatggaa acgagaaaca
    11281 gaggaattta taggaaagtc aggcttttga gattgtgggt gatttttgtt ataatgaaag
    11341 tcatgaaatc ttataatacc ttgaatgatt attatcgaaa actctttgga gaaaagactt
    11401 ttaaagtccc tattgatgcg ggatttgact gtcccaatcg tgatggaact gtggctcatg
    11461 gaggctgtac tttttgtacg gtttcaggtt ctggagatgc tattgtagcc ccagatgcgc
    11521 ctatccgtga gcaattttat aaggaaattg actttatgca ccgtaagtgg ccggatgttc
    11581 agaagtatct ggtttatttt caaaatttta ccaacaccca tgaaaaggtg gaagttgttc
    11641 gagagcgtta tgaacaggct atcaatgagc caggtgtggt aggtatcaat attggaacgc
    11701 gcccagactg tttaccagac gaaaccatcg aatatttggc tgagttatcg gagtgcatgc
    11761 atgtgacggt tgaattgggc ttgcaaacta cttatgaagc aacctctgac ctgattaacc
    11821 gtgcgcattc ttatgaattg taggtggaaa cggtcaagcg tttgagaaag tatccaaaaa
    11881 ttgagattgt ttcccatttg atcaatggtt tgcctggtga aacccatgag atgatggttg
    11941 aaaatgtccg ccgttgtgtc acgaataacg atattcaagg gattaaactg catttgctcc
    12001 atcttatgac aaatactcgt atgcaacgag attaccatga gggacgttta caattgatga
    12061 gtcaggacga atatgtcagg gtcatctgtg accaactgga aatcattccc aaacatatcg
    12121 tcatccatcg aattacagga gatgcgccta gggatatgct gcttgggctt atgtggagcc
    12181 tcaataaatg ggaagctctc aacagcattg agatggagat gcgacgtcgt ggaagtgttc
    12241 aaggatgcaa ggctgtaaaa caggagtttg aaaatgaaaa gaccacttga gatggcacat
    12301 gattttttgg ctgaggtcgt gacaaaagag gatgtcgtag tggatgcgac tatgggaaat
    12361 ggtcatgaca cgcttttttt agccaagcta gccaagcaag tctatgcctt tgatattcag
    12421 aagcaagcct tggaaaagac ccaagagcgt ttgcatcagg ctggcttgac aaatgcccag
    12481 ttaatcttgc aaggccatga gacactggac cagtttgtga caaaagctaa ggcagggatt
    12541 tttaatttgg gctatttgcc gtcagctgat aagtctgtca tcacccgacc gcagacaacg
    12601 attgaggcat tagaaaagct atgtggctta cttgtcaaag gtggacgaat tgctattatg
    12661 atttactatg gtcatgaagg aggcgacctc gagagagatg ctgtcttgga ttttgtgatc
    12721 cagttgaacc aacaagagta cacagctgcc atttaccgaa ctttaaacca agtcaacaac
    12781 ccgccgtttt tagtgatgat tgaaaaatta gagagataca gacatggata aacaatacct
    12841 acacgaaaag ctggatgcca tgcgccagaa ttttgttgaa tcaacccacc acgaacgagc
    12901 ggtgggcgtg ctagaccaag cgcatatgag caaaaaaatg cttaaaatca agaaaaaatt
    12961 agttgctctt gaaatggaac ggtgccagag aaaaattgag cacaaagact gttccaagat
    13021 tgaccaaaaa atcaaagagc agaaggagat atttgaatcc tgttgtaaaa aagattaagg
    13081 aggacgtgcg tggaattact gatttacctc atcctatttt tactggtttt gattgtctca
    13141 agtacaacca ataagctcct gccctttttg cctctccctt tggtgcagat tcttttggga
    13201 attgtgattg gtctcttttt acccaatact gactttcacc ttaatacgga gttgtttttg
    13261 gcactggtta tcggaccctt gcttttccga gaggctgaag aagcagatgt tacggctatt
    13321 ttaaaacact ggcgaatcat tgtttatctc atatttccag tgatttttat ctcgaccctg
    13381 agtttgggtg gcttggccca tcttctttgg ttcagccttc ccttggcagc ttgcttggct
    13441 gttggtgcag cccttggtcc tacggacttg gtggcctttg cctctctttc ggagcgtttt
    13501 agctttccta agcgcgtgtc caatattctt aagggcgaag gactcttgaa tgatgcttct
    13561 ggtttggtgg cttttcaggt agctttgaca gcttggacaa ctggagcttt ttctctgggg
    13621 caagctagca gttcgctcat cttttcaatc ctaggcggtt ttttaattgg atttttaaca
    13681 gccatgacca accgcttcct ccataccttc ttgctaagtg tgcgcgcaac ggatattgcc
    13741 agtgaacttt tattagaatt gagtttgcct ctagtgacct tctttctggc agaagaagtc
    13801 catgtttcag ggattattgc cgtcgtagtt gctggaattt taaaggcaag tcgcttcaag
    13861 aaaatcacgc tcctcgaagc ccaagtggat acggtgaccg agacggtctg gcatacagtg
    13921 acctttatgc tcaacggttc tgtctttgtg attttaggga tggagttgga aatgatagca
    13981 gaacctatct tgaccaatcc aatctataat cctctacttt tattgctatc tctcatcgcc
    14041 cttacctttg tcctctttgt cattcgtttt attatgatct atggctatta tgcctataga
    14101 acccgacgcc tcaagaaaaa gctaaataag tatatgaagg acatgtttct cttgaccttt
    14161 tcaggtgtta agggaacggt gtcgattgct acgattctct tgataccaag taatctagaa
    14221 caggagtatc ctctcttgct tttccttgtt gcaggtgtga cgcttgtcag ctttttaaca
    14281 ggtctcttgg tcttgcctca tctttctgat gaagaggaag aaagcaagga ttatctcatg
    14341 catatcgcca ttttgaatga agtaacgcta gagttggaaa aagagttgga agacaccaga
    14401 aataaacttc ccctctatgc ggctattgac aattatcatg gacgtattga aaatctcatt
    14461 ttaagccaag aaaaccagga tgatcaagaa gattgggctg ctttgaaact cttgattctt
    14521 agtattgaaa gtgatggttt ggagcaggcc tatgaagagg ggaacattag caatcgtgct
    14581 taccgagttt accaacgtta tctgaaaaat atagaacaag gaatcaatcg taaacttgcc
    14641 tcaagactga cctattattt ccttgtttct ttgcggattt tacgttttct ccttcatgaa
    14701 gtttttactc tcggaaagac cttccgtagc tggaagaaca aggagcaaag ccgtctccgt
    14761 gctcttgatt atgaccaaat tgcagagctc tatcttgcca atacagagat gattattgaa
    14821 agtttggaaa acctgaaggg agtctacaga cgctctttga ttagttttat gcaggagtct
    14881 cgtcttcgag aaacagctat tatcagcagt ggtgcctttg tcgaacgggt tatcaatcgt
    14941 gtcaaaccca acaatatcga tgaaatgctg agaggctatt atctggagcg caagttgatt
    15001 ttcgaatacg aagaaaaacg attgattacg actaagtatg ccaagaaatt acgacaaaat
    15061 gtaaataact tagagaacta ttccttgaag gaagctgcca ataccctacc gtatgatatg
    15121 gtggaattgg taagaagaaa ttagttaata ctcttcgaaa atctcttcaa accacgtcag
    15181 cgtcgcctta ccgtatgtat gtgactgact tcgtcagtct tatctacaac ctcaaaacag
    15241 tgttttgagc agcttgcggc tagctttcta gtttgctctt tgattttcat tgagtataag
    15301 attataaatg aaggagtatg acatgaaaaa gtggtggaaa gagctgatag acaaaccttt
    15361 attaaaagct tttttgcatt attatcaagc atcagatagt gagttgacca gtgtcgcagt
    15421 agcctactat tggttgattt cgattttccc cctgcttttg gtggtggtca atatcctccc
    15481 ctattttcag attcctgtgg gagaattttt gggctttatg aaagacgtcc tgcccccaag
    15541 cctctatgaa ggtgtggaaa aaatagccag agaagtcttg acgcaacctt caacaggttt
    15601 attgagtttt tctgttttat cggcgttatg gagtttttca aaatctatga atttcttgca
    15661 aaaagctttt aacaaggctt atggcgtcga aaagagtcgt ggacttattt cccatcagat
    15721 gctaagtctc ctagtcagtt ttggcttgca gctcctcttt gcgtttgcct tgtttttgat
    15781 cttatttggt cagatgattt tggctttact tgctcattat tggacaaaag atggcattat
    15841 ctatcaggct ttacaagggt tggcaggtcc tctgatttac gccctcctct ttgctatctt
    15901 gatcatgctt tattattttc ttcccaatct atctaacagg aaaattagct ataccctacc
    15961 aggcagtgcc tttgttctct tagtgatttt aggtttacta actctgttct ctagttatct
    16021 caattactat gtccatcatt tggtggatgt ccgaatttta ggttccgttc ttcttgttgt
    16081 tatgatgttt tggtttatct tgattgctaa aattgttatc ctaggcgcgg tgatcaatgc
    16141 cagtatgcag agtttgaaag atccggtctt taaaaaagac taactattta tccattacaa
    16201 aagcgcatag tatcaagatt ctataaagcc ttgatactat gcgcttttgt gctttgacag
    16261 ttttttgtat agtttttgtc caagatttct aaatcatctg attaaattcc tattttcccc
    16321 tatcattgtc cctgtttttt cgaaaatgga aggagtataa taaatctatc aataaaatga
    16381 taggaggaac tttatgggtc atattttctt ttttctaagt gtctttttgg cagggattct
    16441 atccttcttt tctccttgta tcttaccttt gttaccggtc tatacaggag tgttactaga
    16501 tgataaggat ggtgctcagg cttctagcgg caaattttca atctcagtta ctagtttatt
    16561 acgaactctg gcctttatag caggaatttc ctttatattt attttgttgg gctatggagc
    16621 tggtttttta ggcgatttgc tttatgcttc ttggttccaa tatcttactg gggcaattat
    16681 tatccttctt ggtttgcacc aaatggagat tctacacttt aaggggcttt ataaggaaaa
    16741 gaggctacaa ctgcaaggac aggggcaaaa tggtaagggc tatagtcagg catttttatt
    16801 gggcttgacc tttagttttg cttggacgcc ttgcgtgggg ccggttctgg ggtctgtttt
    16861 ggccttggcg gcttcaggtg gttcaggagc ttggcaggga gctggtctca tgttggtgta
    16921 tacgctgggc ttggcgctac cattcttgct tctagctctg acctctagtt atgttttgaa
    16981 acatttccga aaacttcatc cctatctcgg aatcctcaaa aaagtgggtg gttttctcat
    17041 tattgtgatg ggattcttgg ttctgtttgg aaatgcttca attttaagtc aattatttga
    17101 ataaaatgga aaggaatatc aatatgaaaa aatggcaaac atgtgttctt ggagcaggtt
    17161 cgctcctttg tttgacggct tgttcaggca agtccgtgac tagtgaacac caaacgaaag
    17221 atgaaatgaa gacggagcag acagctagta aaacaagcgc agctaaaggg aaagaggtgg
    17281 ctgattttga attgatggga gtagatggca agacctaccg tttatctgat tacaagggca
    17341 agaaagtcta tctcaaattc tgggcttctt ggtgttctat ctgtctggct agtcttccag
    17401 atacggatga aattgctaaa gaagctggtg atgactatgt ggtcttgaca gtagtgtcac
    17461 caggacataa gggagagcaa tctgaagcgg actttaagaa ttggtataag ggattggatt
    17521 ataaaaatct cccagttcta gttgacccat caggcaaact tttggaaact tatggtgtcc
    17581 gttcttaccc aacccaagcc tttatagaca aagaaggcaa gctggtcaaa acacatccag
    17641 gattcatgga aaaagatgca attttgcaaa ctttgaagga attagcctag gaggcgtctt
    17701 atgaatgata agttaaaaat cttcttgttg ctaggagtat tttttctagc cataaccggt
    17761 ttctatgttc tattgatacg aaatgcaggg cagacagatg cctcgcaaat tgaaaaggcg
    17821 gcagttagcc aaggaggaaa agcagtgaaa aaaacagaaa ttagtaaaga cgcagacttg
    17881 cacgaaattt atctagctgg aggttgtttc tggggagtgg aggaatattt ctcacgcgtt
    17941 cccggggtga cggatgccgt ttcaggctat gcaaatggta gaggagaaac aaccaagtac
    18001 gaattgatta accaaacagg tcatgcagaa accgtccatg tcacctatga tgccaagcaa
    18061 atttctctca aggaaatcct gcttcactat ttccgcatta tcaatccaac cagcaaaaat
    18121 aaacaaggaa atgatgtggg gacccagtac cgtactggtg tttattacac agatgacaag
    18181 gatttggaag tgattaacca agtctttgat gaggtggcta agaaatacga tcaacctcta
    18241 gcagttgaaa aggaaaactt gaagaatttt gtggtggctg aggattacca tcaagactat
    18301 ctcaagaaaa atccaaatgg ctactgccat atcaatgtta atcaggcggc ctatcctgtc
    18361 attgatgcca gcaaatatcc aaaaccaagt gatgaggaat tgaaaaagac cctgtcacct
    18421 gaggagtatg cagttaccca ggaaaatcaa acagaacgag ctttctcaaa ccgttactgg
    18481 gataaatttg aatccggtat ctatgtggat atagcaactg gagaacctct cttttcatca
    18541 aaggacaagt ttgagtctgg ttgtggctgg cctagtttta cccaacccat cagtccagat
    18601 gttgtcacct acaaggaaga taagtcctac aatatgacgc gtatggaagt gcggagccga
    18661 gtaggagatt ctcaccttgg ccatgtcttt acggatggtc cacaggacaa gggcggctta
    18721 cgttactgta tcaatagcct ctctatccgc tttattccca aagaccaaat ggaagaaaaa
    18781 ggctacgctt atttactaga ttatgttgat taatactctt cgaaaatctc ttcaaaccac
    18841 gtcagcgtcg ccttaccgta tgtagggtta ctgacttcgt cagttttatc tacagcctca
    18901 aagctatact ttgagctgac ttcgtcagtt ttatctacag cctcaaagct atactttgag
    18961 ctgacttcgt cagttttatc tacaacctca aagctatact ttgagctgac ttcgtcagtt
    19021 ttatctacaa cctcaaagcg gtactttgag aaacctgtgg ctatcttcct agtttacttt
    19081 ttgattttta ttgagtataa gaggtctttc ctaagcagtt agaggagaat tttgctatac
    19141 tgatactagt aagtggtaaa ggagcagatc atgacctaca caatcttaat cgtagaagat
    19201 gaatatctgg taagacaagg tttgactaaa ctggtcaatg tagcagccta cgatatggaa
    19261 atcatcggtc aggctgaaaa tggaaggcag gcttgggaat tgatccaaaa gcaggtgcca
    19321 gatatcattt taaccgatat caacatgcct catctaaatg gcatccagtt ggccagtctg
    19381 gtacgagaaa cctatcctca ggttcatttg gtctttttaa caggttacga tgattttgat
    19441 tatgccttgt ctgctgtcaa actaggtgtg gacgactacc tgctcaaacc cttttctcgt
    19501 caggatattg aggaaatgtt ggggaaaatc aaacaaaaac tagacaagga agagaaagaa
    19561 gagcagttac aagatttatt gactaatagg tttgaaggaa acatggccca gaaaatccag
    19621 tctcatctgg ctgatagcca atttagttta aagtctttag ccagtgactt aggttttagt
    19681 ccgacctatc tgagttcctt gattaagaaa gagttgggct tgccttttca ggattatctg
    19741 gtgagagaac gtgttaaaca agccaagctc ttgcttttaa ctacagatct gaagatttat
    19801 gagatcgcag agaaggttgg ttttgaagat atgaactatt ttacccaacg ttttaagcag
    19861 attgcaggtg tgacacctcg tcagtttaag aagggagaag accgatgaag cgttcttctc
    19921 ttttagttag aatggttatt tccatctttc tggtctttct cattctccta gctctggttg
    19981 gaactttcta ctatcaatca agttcttcag ccattgaggc caccattgag ggcaacagcc
    20041 aaacgaccat cagccagact agccacttta ttcagtctta tatcaaaaaa ctagaaacca
    20101 cctcgactgg tttgacccag cagacggatg ttctggccta tgctgagaat cccagtcaag
    20161 acaaggtcga gggaatccga gatttgtttt tgaccatctt gaagtcagat aaggacttga
    20221 aaactgttgt gctggtgacc aaatctggtc aggtcatttc tacagatgac agtgtgcaga
    20281 tgaaaacttc ctctgatatg atggctgagg attggtacca aaaggctatt catcagggag
    20341 ctatgcctgt tttgactcca gctcgtaaat cagatagtca gtgggtcatt tctgtcactc
    20401 aagaacttgt tgatgcaaag ggagccaatc ttggtgtgct tcgtttggat atttcttatg
    20461 aaactctgga agcctatctc aatcaactcc agttggggca gcagggcttt gccttcatta
    20521 tcaatgaaaa ccatgaattt gtctaccatc ctcaacacac agtttatagt tcgtctagca
    20581 aaatggaggc tatgaaaccc tacatcgaga caggtcaggg ttatactcct ggtcacaaat
    20641 cctacgtcag tcaagagaag attgcaggaa ctgattggac ggtacttggc gtgtcatcat
    20701 tggaaaagtt agaccaggtt cggagtcagc tcttgtggac cttgcttggg gccagtgtca
    20761 catctcttct tgtctgtctc tgcttagtgt ggttcagtct taaacgctgg attgctcctt
    20821 tgaaggattt gagagaaacc atgttggaaa ttgcttctgg tgctcaaaat cttcgtgcca
    20881 aggaagttgg tgcctatgaa ctgagagaag taactcgcca atttaatgcc atgttggatc
    20941 agattgatca gttgatggta gctattcgta gccaggaaga aacgacccgt cagtaccaac
    21001 ttcaagccct ttcgagccag attaatccac atttcctcta taacactttg gacaccatca
    21061 tctggatggc tgaatttcat gatagtcagc gagtggtgca ggtgaccaag tccttggcaa
    21121 cctatttccg cttggcgctc aatcaaggca aggacttgat ttgtctctct gacgaaatca
    21181 atcatgtccg ccagtatctc tttatccaga aacaacgcta tggagataag ctggaatacg
    21241 aaattaatga aaatgttgcc tttgataatt tagtcttacc caagctggtc ctacaacccc
    21301 ttgtagaaaa tgctctttac catggcatta aggaaaagga aggtcagggc catattaaac
    21361 tttctgtcca gaaacaggat tcgggattgg tcatccgtat tgaggatgat ggcgttggct
    21421 tccaagatgc tggtgatagt agtcaaagtc aactcaaacg tgggggagtt ggtcttcaaa
    21481 atgtcgatca acggctcaaa cttcattttg gagccaatta ccagatgaag attgattcta
    21541 gaccccaaaa agggacgaaa gttgaaatat atataaatag aatagaaact agctaactcc
    21601 cagtcaattc tgggagtttt atgcgtaatt gggcaaactt tataggttgt ctatcttgct
    21661 aaaaacaaga aaaaacggta tgatagaaga gtgacaacag aggtaacaga gatgaacgag
    21721 acacagattc aaagagaaac acgtcaggta gtggaagatg ttttagaaaa gaccaatttg
    21781 aagcaggggg tcctttttgt tttaggtcta tcttctagtg aggtgctagg tggtcagatt
    21841 gggaaagaat ccagtcaaga gattggtgag ctgatagtgg agactatctt gggtattcta
    21901 ggtagtagag gtatccattt agcagttcaa ggttgtgagc atgtcaatcg ggctctcgtt
    21961 gttgaacgtc aggtggcaga gcagtttgat ctggaaattg tcagtgtcca tcctactctt
    22021 catgcaggag gttcggggca gttggcagcc tttaagttta tgcaggatcc agttgaggtt
    22081 gaatttatca aggctcatgc tggattggat atcggagaca ctgcaattgg catgcatgtc
    22141 aagcatgttc aggttccgat tcgccctatt ttgagagaga ttggtcatgc ccatgtaacg
    22201 gcactggcta gtcgtccaaa attaatcgga ggtgcgcgtg cgcactatcc gcaagacgct
    22261 attagaaagt cttgagaatg aataaaggag ataaaagtgt ttaaaaaaga ccgtttttca
    22321 attcgtaaga ttaagggagt tgtaggctct gtatttcttg gaagcctttt gatggctcct
    22381 tctgtagtgg acgcagccac ctatcactat gtaaataaag agattatttc acaagaagct
    22441 aaagatttaa ttcagacagg aaagcctgac aggaatgaag ttgtatatgg tttggtgtat
    22501 caaaaagatc agttgcctca aacagggaca gaagcatctg ttttgacagc ttttggtttg
    22561 ctgactgttg ggagcttgct tttaatctac aagagaaaga aaattgctag cgtctttcta
    22621 gttggagcta tgggattggt agttcttcct agtgcagagg ctgtagaccc agttgcgacc
    22681 ctagcgctgg ctagtcgaga gggtgttgtt gaaatggatg gctatcgcta tgttggttat
    22741 ctatcaggtg acatcctcaa aacgcttggc ttggacactg ttttagaaga aacctcagca
    22801 aaacctggag aggtgactgt agtcgaagtt gagactcctc aatcaacaac aaatcaggag
    22861 caagctagga cagaaaacca agtagtagag acagaggaag ctccaaaaga agaagcacct
    22921 aaaacagaag aaagtccaaa ggaagaacca aaatcggagg taaaacctac tgacgacacc
    22981 cttcctaaag tagaagaggg gaaagaagat tcagcagaac cagctccagt tgaagaagta
    23041 ggtggagaag ttgagtcaaa atcagaggaa aaagtagcag ttaagccaga aagtcaacca
    23101 tcagacaaac cagctgagga atcaaaagtt gaacaagcag gtgaaccagt cgcgccaaga
    23161 gaagacgaaa aggcaccagt cgagccagaa aagcaaccag aagctcctga agaagagaag
    23221 gctgtagagg aaacaccgaa acaagaagat acacagccag aagtagtaga aacaaaagat
    23281 gaggctgcta atcaacctgt tgaagaacca aaagttgaaa cgcctgctgt agaaaaacaa
    23341 acggaaccaa cagaggaacc aaaagttgaa caagtaggtg aaccagtcga gccaagagaa
    23401 gacgaaaagg caccagtctc tccagaaaag caaccagaag ctcctgaaga agagaagact
    23461 gcggaagaaa caccgaaaca agaagataaa ataaagggta ttggtactaa agaaccagtt
    23521 gataaaagtg agttaaataa tcaaattgat aaagctagtt cagtttctcc tactgattat
    23581 tctacagcaa gttacaatgc tcttggacct gttttagaaa ctgcaaaagg tgtctatgct
    23641 tcagagcctg taaaacagcc tgaggtaaat agcgagacaa aagctgaaaa agttgcagct
    23701 aatacagatg ctaaacaaag tgaagtaaat tctgagactg caagtcttaa aacagcaatt
    23761 tctggattaa atacagataa agttgaactc gaaaatcaac ttaagattgc acagggaaaa
    23821 actgaaactg atttcagcat ggaatcttgg acggttttga gtacagctaa aaataaagct
    23881 caggaagtaa aagataacgg aacagcgacc caagaacaaa taaacgaagc agagaaaagt
    23941 ttgaaaacag cccttgctga cttatctgtt gacaaaacag ctttgggaag cgctatcgat
    24001 acagctacca agaaaaataa agagaactat acaaatcaaa catgggcaga gttagaaaca
    24061 gttcttacag cagcaaaatc tgtaaacact aacgagtcta aacaaagtga agttaatgaa
    24121 gctgttgaaa aattaactgc aactattgaa aaattggttg aattgtctga aaagccacgt
    24181 ttgactctat ctattgaaaa gagagacata gatcgaaaag ttacggtcac gtatactttg
    24241 gaaaatccag caaatactca aataaaatca ataactgcaa ctctgaaaaa aggagaggaa
    24301 gttgttaagg attttgtttt aacagaagaa aatcttaaaa ctaatcattt aactgctttg
    24361 tttgaaaagc tagattacta caaagaatac actctatcta cggatatggt atataacaga
    24421 ggaaatgatg atgagacgga gagtatttca gaagaactaa ttcagctgaa tcttaagaaa
    24481 ctagaattga aagatatcca gacagtctct ctgatgaaat ttgaaaatgg tcaagaaagt
    24541 caggttacac acttgtctga taaaccgacc gatttgagta aattatactt aaaagttaca
    24601 tcatcaacgt ctaaggatgc tgtgttagcc gttagctcta tagaagaaga gattgttgaa
    24661 aataaaaaaa tctttaaaat tcatgcagat acaccagaat tagtagttcg taagaaagat
    24721 ggcagtcttt ctaagggatt tgactattac atggagagag ttatccctca tgatggtgat
    24781 atttattatg attttaaaga cttgatttca gctatgacat ctaatcctac aggtacgttt
    24841 attttaggga gagatatttc ctcgcgtaat gtaaaaccgg atggaaatgg aaaatcttat
    24901 atcaaaggtg aatttaaagg aaaactactt ggtacaaatg ataatgttag acactcgatc
    24961 tttgacttag aatatccatt gtttgatact ataaaatcag gagtcgtgaa agatattgat
    25021 ttcaagcatg tcaatatggt attcccagat agcaatcaag gagataacgt agcaacaatt
    25081 gcaagagtaa tcaaagataa gacaaaaatt gagaatgtta atgttgaagg ttatctcgag
    25141 ggtcgagatc atgtagctgg tttagttaat aatcttgaag gtaattccga aattgaaaat
    25201 atatccttta caggaaagat taagtctaaa ggtggtaatt ctattacagc aggtattgca
    25261 ggtagaaata tcttatctcg tgttaaacgt gcctatgtaa atgcaaatat tgaagtcctt
    25321 ggttcaacga attcgagtat gcttgttgca gtaaatggta caacattgaa tgctagtgga
    25381 ggttggggag cctggggaag acttactgag tccgttgcta aagggacgtt agaaattaaa
    25441 cgcagtggac aagctggtgg agttactgca acagtctggc cttatggagc aattgataag
    25501 gttgtcagct atgcaaaagt taccaaagga aaagaattat ttgggtcaga tggtgattta
    25561 aataataatt ggtttatgca aaaaattaat aatatttttg gtgttcaagg tatcagctca
    25621 ggtgactcag ggaatgattc taagtttaag cgtatttccg aggaagaagc aaagcaaaag
    25681 gttgcctctt ataatattac agctcccaac ttgatgagcg actcaagtct tttggtagac
    25741 agactcaatg aaagttggaa aaatactgat caatttgaaa gtatacagga ttatcaatcc
    25801 caaaaccaat taatttacca gaacttgact aaatttactc cttattacaa taaagaattt
    25861 attgttcatg aaggaaatgc tctcactcct gaacaggaaa tattgaagac taagaaaatc
    25921 aaatcgattg tagggttgaa aggaacagag ttcgttgtag atggcagtga tattgatact
    25981 atcatgcttc attttgagga tggtagtcag aagcgatata aggtaacctc tactggtaag
    26041 ttttcgataa ctaatttacc ggaatatcag gttgaagatt taaatgtggt gtatacatca
    26101 gaacatatag tacatccact agattcgtca ctgataaata accttgttga agaattgaaa
    26161 aaagtagaat tgtatacaga gtctacttac caagttctag gtattgataa agataatgct
    26221 aacaaattga atagaactaa gagattattc ttagatgagt cattagatgc tgttaaaaca
    26281 caattgccta cctttgtaaa aacaatgttt gaaaatgagt ggttgcacat caatggagaa
    26341 tctagtggag ctgtcgctgc tttacgacaa aaaatcatgg ataataagac ggctatattg
    26401 cttgctttga cttatatcaa tcgttattat gatgttaaat tctcagacta taatattaaa
    26461 aaactgatgc tctttaaacc aactttccat ggtgaaaaga ttgatctatt agatcgatta
    26521 atccgactag gatcatctgg agaaaataga ttaaaaggtt cagaaaatgc agaaacgttc
    26581 aagcagttat ttgctagcga aacgaagcag aaggatttgg tgacttattt agactacaat
    26641 cgctctttgt tgactaatta tcaaacaaca ggggaatggt ttaaagaaac gactaaggat
    26701 tatattcaat ttgaggaacg tccatcctta gtagaggaga ttaaagatgc caaatatcga
    26761 gtttacgata atttaaccgc accgtattat caaggatata tcctacctct cttaacgttg
    26821 aagaatactc atttagcaat tttatcgaac tatagtacta tgacatttgt cagccgtgaa
    26881 aaacgcccta attggaaaaa tgaagatttt gataagtggg tgaaatatgt agcaactgct
    26941 catagaaacc atgttgatac ttggtataag attttacctg ataatatcaa aggtaaaatg
    27001 gttaaagaga atgttactgc tgtttgggaa ggattgagca tcccaggaag tgaatgggta
    27061 gaccagaatg ctgtagatag aaaaggaaga gattacgccc cagctcgaga attctttaat
    27121 cttgtaggtg gtcctatggg aggttggtat gcttaccatg gttatggtgc gcatgctgga
    27181 ggaagaaatc gggttaatta tgaggtgttt gatgtattaa gtgagtatgg tatatcggtc
    27241 tttactcatg aattgactca cgttaatgat acttggattt acttaggagg gtatggtaga
    27301 cgtgaaaata tgggacctga agcttatgct cagggattat tccagtctcc tgttccaggt
    27361 cagccgggtt ggggggcgct tggtctcaat atggcatttg aaagaaaaaa tgatggtgat
    27421 ctaatttata atgcctcccc aactcaattt gaaaatagga aagagttaga tagttatatg
    27481 aaaaattata acgatactct catgatggtg gactacttgg aaggagatgc agttatctct
    27541 aaaggtaaag aagctattac taaatggttt aaaaaagttg aacctaaggt tgttagtcaa
    27601 acagctcagt atgatacggt tcgtcagttg actgctgaag agaaagaaaa actttctgtt
    27661 tctagtgttg atgatttagt tgatcaagga ttaatgtcag acagagctgt aggaaataat
    27721 acctataatc cagctgattt tgaaacaagt tatattgcga tagattatat gactggtatt
    27781 tatggtggag gaaagaatag tgtaggttca ccaggtgcct tgatgtttaa acataatact
    27841 ttccgtatgt ggggctacta tggttttgaa gaaggtgttc taggatatgc ttctaataaa
    27901 tttaagcaag catctagaga tgaaggtcat gctggactta gtgataactt tattatttct
    27961 aagatttcca aaggggaatt tttaactatg gaagcattta aaaagggata ttttaagaaa
    28021 gtagtagaag agttaaaaac taaaggtatt cgtcctgtta ctatcaatca aaaaacatat
    28081 agcacctttg aagaattgca agaaggattt aagcaggctg ttgaaagaga tttgaagaaa
    28141 aatcagttag atgagaggga aacaagaaac ttcaaattcc aagttttcag acaacttctt
    28201 caacaaacag atagctttaa aacttctatc tttagataat cgaaatctct catctgcttt
    28261 gcggatgagg gttttcttat tttatgctat acttaaggta tgcatagaaa aacagtgatt
    28321 gattttagga ctttagggga gagatatacc tttacccagc ctattaaaga gttgaaaacg
    28381 agaaatgtag aagaagtggc agatttgctg gcacaagtgg aaagctacca agagcaaggt
    28441 tattatgtgg tggggtatgt cagctacgag gctgcacctg cttttgagga aaaattagca
    28501 gttcacaagg atcccctact gggagagtac ctgctttatt ttactgttca tgatagcgta
    28561 gaaacttccc ctattcctct gacttatgag gatattgatt tgccctcaaa ttggcaggaa
    28621 gtaacgtctg cagcagacta tgaaaaggcc attgcccaga tacaccatca cttgaggcag
    28681 ggagacacct atcaggtcaa ctacaccgtc caactcaagc aaaagttaag tgccaatcct
    28741 tttgccatct acaatcgtat ggtggtagag caggaggcgg gctacaatgc ctatgtggaa
    28801 catgacgaga tggcagtgat ttccatgagc ccagagctct tttttgagca aaatgatcgc
    28861 gagttgacaa cacgaccaat gaaggggacg actcagcgtg gggtaactga ccaagaagat
    28921 cttgaacagg ccagttggtt ggaacaggat cccaaaaatc gctctgaaaa tatgatgatt
    28981 gtggacctct tgcgcaatga tatgaaccgt atttctgaag ttgggagcga gcacgtggag
    29041 cgtctgtgcc aggtagagca gtattcaact gtttggcaga tgacttcgac catcaagagt
    29101 cagttgcgag aggatgtgga ccttgttgaa atcttccgct cactctttcc ttgtggttcc
    29161 ataacgggtg caccgaaaat tgcgacaatg gagattatca agaacttgga gcctcaaccg
    29221 cgtggagtct actgtggaac gattggtctc ttgcttccaa atggacgacg gatttttaat
    29281 gtggccattc gtaccattca acttcacaaa ggtcaagcca tttatggagt tggcggaggg
    29341 attacttggg atagcacatg ggaatctgaa taccgagagg ttcatcaaaa ggcagcagtt
    29401 ctttatcgta aacaagctcg cttccaactg attacgacag gggaaatcag ccagaagaac
    29461 ctgctgtttg aagatcaaca tctggaaaga ctgagaaaag ctagtcgtta ttttgccttt
    29521 ccttttgatg cagaagactt gggacacaag attgaggaag agtgtcagga ttgtgaagct
    29581 aatcaagatt accgcttgcg aatcagcctt agcaaatctg gagagataga agtcaatcgt
    29641 caagtattaa cccctctcag tacaagcttt tgtcaggccc aagtctgcct tcaggaagct
    29701 gctttgaatc aatcctttac ctactttaaa accactcacc gaccgcattt gagcctagga
    29761 gaacaagaga agatttacca caataagtca ggagaactgc ttgaaacctc tataggaaat
    29821 ttggttctga aaatcgctgg aaaactctac acaccgccta tccgacttgg aatcttgcca
    29881 ggaatttacc gtcagcattt gctagaaaca ggacaggtag aagagaaagt cttgaccttg
    29941 gcagatttaa cccaagcaga agctatttac ggctgtaatg cagtgagagg cttgtatgaa
    30001 ctaagccttg aggagaacta gatgaaattg atatttttgc atgggttagg gcagtcagca
    30061 gagtcttgga aagaagttcg gaatctactg acagattatc cttctgaggc tatcgagtta
    30121 tttccttctg gagttagtaa ctatcaacaa gctaaagagc gagtttatca gcacctagct
    30181 caagagacag aaccttttgt tttgattgga ttgtccttag gtgctgccct gacactagaa
    30241 ctttccagtt acgatttacc aaatcttcga gctttgattc tgtcaggatg cccgcttaaa
    30301 ttagcaggga atatcctatt ttatcttcag ttgctgattt ttaaactact tcccaaaaga
    30361 gtatttgaaa aacagggagc agacaagact cttatggtcg gagtttctga ggaattgaag
    30421 acacttgatt taacggatat agcagggact tgctcctatc caaccttact aatttgtggc
    30481 cgcaaagata aaccgaatct tagttttatg aaagctctcc atagactgtt aacagattcg
    30541 cagtttcaga tcattcctga tggccctcat gtcttgaata aggcaaaacc aaaggagttt
    30601 gtagaaaaga ccagaagttt ccttgaattg ctgaaataag tttgataaaa taatattgaa
    30661 atcgatatca taattatggg agaaagaaat gaataaacgt ctatttttaa aaatgagtct
    30721 ggtgacgttg ccaattttag ccttgttttc acaaccagtt ttggcggaag aaaacatcca
    30781 tttttcgagc tgtaaggaag cttgggcgaa tggctattcg gatattcacg agagagaacc
    30841 tggttattct gccaagttag accgtgatca tgatggtgtg gcttgcgaat tgaaaaatgc
    30901 tcctaagggt gcttttaaag caaaacagtc aacggctatt caaatcaaca caagttcagc
    30961 aacaacaagt ggttgggtta agcaggacgg cgcttggtac tactttgatg gaaatggaaa
    31021 tctagtgaaa aatgcatggc agggaagcta ttacctgaaa gctgatggta aaatggcaca
    31081 gagtgaatgg atttatgact cttcttatca agcttggtat tacttgaaat cagatggttc
    31141 atatgctcgc aatgcatggc aaggaaacta ctatttgaaa tcagatggta aaatggctaa
    31201 aggtgaatgg gtttatgatg ccacctatca agcttggtat tatttgacat cagatggttc
    31261 ttatgcttac agtacatggc aaggaaatta ctatctaaaa tcggatggta aaatggctgt
    31321 caatgaatgg gttgatggtg gacgttatta tgttggcgct gacggagttt ggaaggaagg
    31381 tcaagcaagt acagtttctt ctagtaatga tagcaatagt gaatattctg ctgctttagg
    31441 aaaggcaaaa agttataatt cgttattcca catgtcaaaa aaacgtatgt atagacaatt
    31501 aacttctgat tttgataaat tttcaaatga tgcagctcaa tatgccattg atcatttaga
    31561 tgattaacag atactggtag gcgaaaaaat tccttataat tcatttacgc aaacctttgc
    31621 ataagtgaat ggattttgat atactagtac tgtaagcatt ttcaattact acacaatgaa
    31681 aaaggagaat atgatgagtc aaaagattat tgggattgac cttggtggaa cttctatcaa
    31741 atttgcaatc ttaacaacag caggagaaat ccaaggaaaa tggtcaatca agaccaacat
    31801 tttggatgag ggaagtcata tcgttgatga tatgattgag tctattcaac atcgtttgga
    31861 cttgcttgga ttggcagcag cggacttcca aggcattgga atgggatcac caggtgtggt
    31921 tgaccgtgac aaagggactg ttatcggtgc ctacaacttg aactggaaaa cccttcaacc
    31981 aatcaaacaa aagattgaaa aagctttggg cattccattt ttcatcgata atgatgccaa
    32041 cgtagcagct cttggtgagc gctggatggg tgctggagat aaccaaccag acgttgtctt
    32101 tatgacactc ggtactggtg ttggtggtgg tattgtcgca gaaggcaaat tgcttcatgg
    32161 tgttgctggt gcagcaggtg aacttggtca tatcactgtt gactttgacc aaccaatctc
    32221 atgtacttgt ggtaaaaaag gctgccttga gacagttgct tcagcaacag ggattgtcaa
    32281 cttgactcgt cgctatgccg atgaatacga aggcgatgca gccttgaaac gcttgattga
    32341 taacggagaa gaagtaactg ctaagactgt ctttgatctc gcaaaagaag gagacgacct
    32401 tgctttgatt gtttatcgta acttctcacg ttacttggga atcgcttgtg ctaacattgg
    32461 ttcaatccta aacccatcaa caatcgtcat cggtggtggt gtgtcagctg cgggagaatt
    32521 ccttctacaa ggtgttcaaa aagtttacga tgaaaatagt ttcccacaag tacgcacatc
    32581 tactaaatta gctcttgcaa ctctaggaaa tgacgctgga gttatcggag cagcatcact
    32641 tgtattgcaa taagataatg agagaggaaa atgctaacct agagttagta atgttcctct
    32701 tttatttttt atgctatact agttaggaca atgaatgagg tgagagtaaa tgacaaaagc
    32761 agatacgatt tttaaagaga atattgaacg cattctaaag gaaggtgttt tctcagagca
    32821 ggctcgtcct aagtacaagg atgggactgt tgctaattcc aagtatgtaa ctggtgcctt
    32881 ttccgagtac gacttatcta aaggagaatt tcctatcaca accttgcgtc ccattgccat
    32941 caaatccgcc atcaaagaag ttctctggat ttaccaagac cagtcaaata gcttagaagt
    33001 gcttaatgac aagtacaatg ttcactactg gaatgactgg gaagttggag acacgggaac
    33061 cattggtgag cgctatggtg ccgttgttaa gaaacacgac attatcaata agcttctcaa
    33121 acagttggaa accaatcctt ggaaccgccg caatattatt tcgctctggg attaccaagc
    33181 tttcgaagaa acagatgggc tgctcccgtg cgcctttcag accatgtttg atgtccgccg
    33241 tatagatgga gaaatctatc tggatgcgac cttgacccag cgctcgaatg atatgctggt
    33301 ggcccaccac atcaacgcta tgcagtatgt ggctttgcag atgatgattg ccaaacattt
    33361 tggctggaag gttgggaagt tcttctactt catcaacaac ctccatatct atgataatca
    33421 atttgaacaa gctcaggaat tgctccgtcg ggagccgtca aactgccaac cacgcttggt
    33481 tttaaatgtt cctgatggga ctaatttctt tgatatcaaa gcagaagatt ttgagttggt
    33541 ggattatgac cctgttaagc cacagttgaa gtttgaccta gctatttaaa agaatagaaa
    33601 aaagaagttg agaataatcc caacttcttt tgtttcttaa cgtgatacgc ggcgacgagc
    33661 tgctttttta cggttttctt cgatgaaagc tgctttttgc tcttctggtt cgattacttt
    33721 ctttttaaat gcgtatactg cacctgcaac ggcagcgaca gttcctgcga cacctgttac
    33781 aagaccttta gcgaatcctt tagccatgag tcttcctcct ttatattctc aatcagccag
    33841 cctcctcaag aggtcacatt tttctgactg acctttttgt gttataataa tagtaacgaa
    33901 aaaatgggaa tttttcaagg aaaaaagatg aaaacaaaaa taattgtgat tgttggaccg
    33961 actgctgttg gaaagacggc tctagctatt gaagttgcaa agcgttttaa tggcgaagtg
    34021 gttagtggag atagccagca agtctatcga ggacttgata ttgggacggc caaggctagt
    34081 ccagaagagc aggcagctgt tcctcatcat ttaatcgatg ttagagagat aaccgagtct
    34141 tactcggctt ttgattttgt ttcagaagct aagatgacta ttgagggtat tcacaaccgt
    34201 ggcaagctag ccattatcgc cggtgggact ggactttata tccagagctt gctagaaggt
    34261 taccacctag gtggggagac tcctcatgag gagattttag cttatcgagc tagtttggag
    34321 ccatattcag atgaggaatt agcccatttg gtggatcaag caggccttga gattccccag
    34381 tttaatcgtc gtcgtgctat gcgtgcctta gaaattgccc attttggtca ggatttggaa
    34441 aatcaagaga ccttgtatga accgctgatt atctgcttgg atgatgaacg tagtcaactt
    34501 tatgagcgta tcaaccaccg agtggatttg atgtttgagg ctgggctttt ggatgaggcc
    34561 aagtggctgt ttgaccattc ccctaatgta caggctgcta aaggaattgg ctataaggaa
    34621 ctctttcctt atttccgtgg agagcagacc ttggaggaag ctagtgagag tctcaaacag
    34681 gcgacccgtc gttttgccaa gcgtcagctg acctggttcc gtaatcgcat gcaggtcacc
    34741 ttttatcaga ttggagaatc tggtgtacaa gaccgcattt taagccagat agaggagttt
    34801 ttagatgatt gaaacggaga aaaaagagga gcgagtcctg ctgattggtg tggaattgca
    34861 gggtatggac agttttgacc tctccatgga agaattggct agtttagcga aaacggcagg
    34921 ggcagtcgtt gtagatagct acagacaaaa acgtgaaaaa tatgattcca agaccttcgt
    34981 cggctctggt aagttggaag agattgcgct tatggtggat gcagaagaaa tcactactgt
    35041 catcgtcaac aaccgtctga ccccaaggca gaatgtcaat ctagaggaag ttctcggtgt
    35101 taaggtcatt gaccgtatgc agttgatttt ggatatcttt gccatgcggg ctcgaagcca
    35161 tgaagggaag ctccaagtcc acctagccca actcaaatac cttttgcctc gcttggttgg
    35221 tcaggggatt atgctcagcc gtcaggcagg gggaattggt tcccgtggtc ctggtgaaag
    35281 ccagctggag ctgaaccgtc gtagcgttcg caatcaaatc acggatattg agcgccagct
    35341 caaggtggtt gagaaaaatc gggcgactgt cagagaaaaa cgtttggagt ctagcacttt
    35401 taagattggt ttgattggtt atactaatgc tgggaaatca actatcatga acatcttgac
    35461 cagtaagacc cagtatgaag cagatgagct ctttgcgact ctggatgcga caaccaagag
    35521 tattcatctg ggaggcaatc tccaagtaac tttgacagat accgttggct ttatccaaga
    35581 tttgccgaca gagttggtgt ccagtttcaa gtcaaccttg gaagaaagca agcatgtgga
    35641 ccttctggtt catgttatcg atgctagcaa tccttaccac gaggagcatg aaaaaacggt
    35701 tctctccatc atgaaagacc tggacatgga agatattcct cacttgacgc tttataataa
    35761 agcggatttg gtggaggatt tcacgcctac ccaaacgcca tataccctca tttctgccaa
    35821 gtctgaggac agtcgtgaaa acttgcaagc attattgcta gataagatta aggaaatttt
    35881 tgaagcattt accctgcgag tgcctttttc aaagtcctac aagattcatg atttagagag
    35941 tgttgcaatt ctggaagaac gtgattatca ggaagacggc gaagtgatta caggctacat
    36001 ttccgagaaa aataaatgga ggttagaaga attttatgac tgatattaaa actttggctc
    36061 taaagtatgg aggttataca agtctggaca aggtctatct ggatcagctt ctagctggta
    36121 aaacagagca ggagcagtta acacttatta cacctccgcc aagtgttgtt aatgcctact
    36181 ttgcagaact ctatcagaaa aaaagtcctc aggctgcgac ggattatttt gcagaactca
    36241 gtcaggaact gaatctttac aatactgagc caagtttcac cctagaaaat aagcctttta
    36301 ttcggcttaa tctgtctggt aaatcctttg gtttttgtta tgagagtgac ggctttggtc
    36361 ggattttctc tgaaaatgag gagaaaatct cggatgactt gctctttgaa attgcgcaaa
    36421 ttttctccca tcaattagtc tttgaagagt ctggtaagat ttacatgaag cctgtcaagg
    36481 acgaggaagt tgtcagccta gaaagtctca cagctttgac tgatttggaa agattggctg
    36541 atggtcgaaa acgtctcaaa ggctacagcc aagaggattt attgcaagaa gctgctgctt
    36601 tttctggcaa acgctatttc cgatcggaaa accgcacagc catgttatat attgattaat
    36661 tagaaagtat cgaatggata ttcaattttt aggaacgggg gctggtcagc cctctaaagc
    36721 ccgcaacgtt tcaagtctcg ccctgaaact tttggacgag attaacgaag tttggctctt
    36781 tgactgtgga gaaggtacgc aaaatcgcat tctggaaacc acaattcgac cacgtaaggt
    36841 cagcaaaatc tttattactc atctgcatgg agaccacatt tttggtttgc caggtttcct
    36901 ttctagccgt gcctttcagg ccaatgaaga gcagacagat ttggaaatct acggacctca
    36961 aggaatcaag tcatttgtct taaccagcct tcgtgtgtca ggttctcgtc tgccctaccg
    37021 cattcatttc catgagtttg accaagattc tctgggtaaa attcttgaaa ccgataaatt
    37081 cactgtgtat gcagaggagc tggaccacac tattttctgt gttggctatc gtgtcatgca
    37141 aaaggatcta gaagggacgc tggatgctga aaaactcaag gctgctggtg ttccgttcgg
    37201 cccgcttttt ggtaaaatca aaaacggcca ggatcttgtt ttggaagacg gaactgaaat
    37261 caaggcagca gactatatct cagcgccacg tccaggtaag attatcacta ttttaggaga
    37321 cactcgaaaa acggatgcca gtgtgcgtct ggctgtcaat gcagatgtcc tagttcatga
    37381 gtccacttat ggcaagggtg atgaaaaaat tgctcgtaac catggtcact caactaatat
    37441 gcaagctgca caagtagcgg tagaagcagg tgccaaacgc ctcctactca accatatcag
    37501 tgcccgtttc ctctcaaaag atataagcaa actcaagaag gacgctgcca caatttttga
    37561 aaatgtccat gtggtcaaag acttggaaga agtggaaatc tagcagtcac agaaaggata
    37621 agtatgccta ctattctcat taccggagct agcggtggtc tagctcaaga aatggtcaaa
    37681 ctcctgccca atgaccaact catcttgctt ggtagaaata aggaaaaatt agcccaactc
    37741 tacggaaatt attcccatgc agaattgatt gaaattgata ttaccgacga ttcagcccta
    37801 gaagctctgg taactgatct ttatctccgc tatggcaaga ttgatgtctt gattaacaac
    37861 gctggttacg ggatttttga gggatttgac cagattgctg ataaagatat tcaccagatg
    37921 tttgaggtca atacctttgc cctgatgaat ctgtctcgtc accttgcggc tcgtatgaag
    37981 gaaagcagca aagggcatat catcaacatc gtcagcatgg caggtctaat agctactggc
    38041 aagtctagtc tttactcagc gaccaagttt gcggctattg gtttttcaaa tgctctgcga
    38101 ctcgaactta tgccctatgg agtctatgtg acaacagtca atccaggacc aatccgtaca
    38161 ggatttttcg accaagccga cccagatgga acttatctta aatcggttga ccgcttcctg
    38221 ctagaaccag atgcagtggc taaaaagatt gtcaagatta taggaaaaaa caaacgagaa
    38281 ctcaatctcc cgattttgtt gaacctagct cataagtttt ataccctctt tcctaagcta
    38341 gctgataagt tggcagggga aacttttaat tataagtaaa aagaaccaat gtgcaggttg
    38401 ttgctagcct acatattggt tcttatcatt tctcaactat caaactgaac ttcttctagg
    38461 aggtagtcta taaagcgttc gcccatctta gataggctgg ttttctcatg ctggatatag
    38521 accagctcaa tcgggtcatc aatatccagt gggatagaaa cgatattgtc tccgtttagg
    38581 ttgctgttca aaatccctgt cgcaatggta taaccatcca aaccaatcaa gagattaaag
    38641 agggtggcac ggtcactgac cacaatggat ttcttgtggt gttcttgaga aagaatctct
    38701 tctgaaaagt agaaggagtt gtgcgtccct tggtcatagc tgaggtaagg gaaattctcc
    38761 aaatcagaca gtttcacctt gtctttcttt gccagagggt tggtcttgct gacaaagata
    38821 tgtggttgcg ctgtgaagag atggtgggct agcaggtgat tgtcatccag catcttggtt
    38881 aaaacatcac ggttgtaact gtttaagaag aggaccccga cctcactgcg gaagttcttg
    38941 acgtcgtcga taatctccca agtccgagtt tcacgaagga agagttcgta tttctccata
    39001 tcgcttttct tgagcaaaga gacaaaggca ttgaccacaa aggcatagtg ttgagacgaa
    39061 acgctaaata gttcgcggtg ggcgacagga tttttatagc gttcctccag aagctgggtc
    39121 tgctcgacaa cctgacgggc ataggagaga aactccatcc catcacgggt caaggtgatt
    39181 cccttgggat tgcggataaa gatctcaatg cccatttcat tttccaaatc tcgcactgca
    39241 ttggagagac ttggctgagt gataaagagt tgcttggctg cctcattcat ggagccagtt
    39301 tcgacgattt tgataatata atgtaattgt tgaattctca tgtttttatt gtaccatact
    39361 tgccttagaa tcgctaaaga agatgggaaa ataaggagca ttgtgtgagt ctcttcttga
    39421 aaaaaacaca aaattttgct agaatgagtc ttatgaaaac attctatgat gtgcagcaat
    39481 tcctcaaacg atttggtatt attgtttaca tgggaaaacg cttatatgat attgaactga
    39541 tgaagttgga actatctcgg atttacgatg cagggttgat ggataaatta gactatctag
    39601 aggcagaagc agttcttcgc agagagcaca aggtagaatt ggattatatt gagaaaaatg
    39661 gagaaaagaa ctaatggtta cttggatttt gtgggcactt atactagcaa tgttggcgtg
    39721 gatgggcttt aactatcttc gtattcgccg tgcggctaaa attgtggaca atgaggagtt
    39781 tgaagccttg attcgtacgg gtcaattgat tgatttgcgc gacccagcag aattccacag
    39841 aaaacatatc cttggtgcac gcaatattcc ttcaagtcag ttgaaaacta gtcttgcagc
    39901 ccttcgtaaa gataaacctg tccttctcta cgaaaaccaa cgtgcgcaac gagttacaaa
    39961 tgcagctctt tacttgaaaa aacaaggttt ttctgagatt tatatccttt cttatggctt
    40021 ggattcttgg aaagggaaag tgaagactag ctaaccttat ttccaaatta gttgaatgat
    40081 aggatgaagc tattgtttta tagtataatt aatttgtata aaatttaagg agttcttaga
    40141 acatgaaaga aaagaagaaa atccactttt tgtgggtatc ttgtcgatta ttcttggttt
    40201 gttatttcca attgtaggcc tgattttggg tatcatagga ttggtcttgg ctatttcata
    40261 ccaaaaagag tcacaattag actataaaat agaaaagatt cttaatatct taggaattgt
    40321 gatttctgta gttaactgga ttgtagcaat cgccttaatt tttcggtaaa taaaagaaaa
    40381 aagctttagt tttaaagctt tttttatttt atcgactcat ctctaaatag tttttaatga
    40441 tttgtaactc tttttggttc aaagggcggt agttaccttc tgctaaatct gggttcaatg
    40501 tgaagtcccc aaattggatt ctcttgaggc tagtcacctt aacaccaacc gagaggaaca
    40561 ttttcttgat ttgatgaaat tttccttctg aaatggtgat agaggcttga ctgatggagg
    40621 gacttgcaga tagaatctct agttttgcgg gtttacagac agtaccatct aaaaagacaa
    40681 ttcccttttg aaaggcttgg atatggtcag gtgttagaag tccattaacc tcaacttgat
    40741 aagtcttatc gacatgatat tggggatgga ggagttggaa gcccaaggga ccgttatcgg
    40801 tcaagagaag gagtcctgtt gtatctcggt ccagtcggcc gacggcatag agcttgtcag
    40861 actggatgtc agatggaagc aggtccatga cggtcggaag ttccttgtct ttgttggctg
    40921 taacgacacc agcaggttta tgaagcataa gataggtgtg ttcatagcct tgaatgattc
    40981 gatcctgaaa aaggagttct tgtagtcctg tatcgatatt ttgagctagg gagcgggctg
    41041 ggcaaccatc gactagaatt tcccctctga ggagtgcttg tttcatggcc tttcggctga
    41101 ttttttcttg agctaataaa ttatctaaac gcatactgtg cctatcttat cataagtcgc
    41161 ttgctttgaa aaggcttgac gtgaaaagaa aagcggagtg aaaacattta cacttgcttg
    41221 agttatgtta tttatttgaa attatggtat aatcgttcag ttagaaaata aattttgaat
    41281 attatagagg aaatcatgac aaaattaaga gaagatatcc gtaacattgc gattatcgcc
    41341 cacgttgacc acggtaaaac aaccctcgtt gacgaattat tgaaacaatc agaaacgctt
    41401 gatgcacgta ctgaattggc agagcgtgct atggactcaa acgatatcga aaaagagcgt
    41461 gggattacca tccttgctaa aaatactgcc gttgcttaca acggaactcg tatcaacatt
    41521 atggacacac caggacacgc ggactttggt ggagaagttg agcgtatcat gaaaatggtt
    41581 gacggtgttg tcttggtcgt agatgcctat gaaggaacca tgccacaaac tcgtttcgta
    41641 ttgaaaaaag ccttggaaca agaccttgtc ccaatcgtgg ttgttaacaa aatcgataag
    41701 ccatcagctc gtccagtaga agtagtggat gaagtcttgg aacttttcat cgagcttggt
    41761 gcagatgacg accagcttga tttcccagtg gtttatgctt cagcgatcaa cggaacttct
    41821 tcattgtcag atgatccagc tgaccaagaa gcgactatgg caccaatctt tgacacgatt
    41881 atcgaccata tcccagctcc agtagataac tcagatgagc ctttgcagtt ccaagtgtcg
    41941 cttttggact acaatgactt cgttggacgt atcggtatcg gtcgtgtctt ccgtggtaca
    42001 gttaaggttg gggaccaagt taccctttct aaacttgacg gtacaactaa aaacttccgt
    42061 gttacaaaac tcttcggttt ctttggtttg gaacgtcgtg aaatccaaga agccaaagcg
    42121 ggtgacttga ttgccgtttc aggtatggaa gacatctttg tcggtgaaac catcactccg
    42181 acagatgcag tagaagctct tccaatccta cacatcgatg agccaactct tcaaatgact
    42241 ttcttggtca acaactcacc atttgctggt aaagaaggta aatgggtaac ctctcgtaag
    42301 gtggaagaac gcttgcaggc agaattgcaa acagacgttt cccttcgtgt tgacccaact
    42361 gattcaccag ataaatggac tgtttcagga cgtggagaat tgcacttgtc aatccttatc
    42421 gaaacaatgc gtcgtgaggg ctatgaactt caagtatctc gtccagaagt tatcgtaaaa
    42481 gaaatcgacg gtgttaaatg tgaaccattt gaacgtgtac aaatcgacac tccagaagaa
    42541 taccaagggt ctgttatcca aagcctttct gaacgtaaag gtgaaatgtt ggatatgatt
    42601 tcaactggta atggtcaaac tcgtttggtc ttccttgttc cagcgcgtgg tttgattgga
    42661 tactcaactg agttcttgtc aatgactcgt ggttacggta tcatgaacca taccttcgac
    42721 caatacttgc cattgattcc aggggaaatt ggtggacgtc accgtggtgc ccttgtttct
    42781 atcgatgctg gtaaggctac aacttactca atcatgtcta tcgaagaacg tggtacgatc
    42841 tttgtcaacc caggtactga ggtttatgaa ggaatgatca tcggtgaaaa ctctcgtgaa
    42901 aatgacttga cagttaacat cacgaaggca aaacaaatga ccaacgttcg ttcagctact
    42961 aaggaccaaa cagctgttat caagacgcct cgtatcttga cacttgaaga gtctcttgag
    43021 ttcttgaacg acgatgagta catggaagta acgcctgagt ctatccgttt gcgtaaacaa
    43081 atccttaaca aagcagagcg tgagaaagct aacaagaaga aaaaatcagc tgaataagag
    43141 ctagaaagag agaaagatgg tctatttagt cctaggaatt ttactgctcc tactctatgt
    43201 atttgcgaca ccagaaagca ttaaagggac tgtcaatatc gtcgctatgg tatgtatttt
    43261 agtggcactc ttgattttat tggttctatc ttttctgaaa atttttcaat taccaacaga
    43321 aatattccta gcaatagcca tgttgatcct agcttacttt agtgttagag acatcacact
    43381 catgccagtc aaaaaaagta aaagaagata aaaaagagag tttcggctct ctttttgcta
    43441 ggaattttac aatagtttga attgcttttt agttaacacc atctctttta cttgtatagt
    43501 atgaatggga aaaacttgaa taaaattcgt taatggcatc tattttatat ttggttagta
    43561 ctggttgcat attattttga aataaaacta ctatataata ttattcatag agataatata
    43621 gtaaaacatc taaaaaattc gattttttcc ttgacaacaa ataataaaaa tgttattctt
    43681 atcacataag aaagcgattt caacaaaaga gagaggagga tttattttgt tgcattgttg
    43741 ctcaaggtgt gatttttttg aaagaaaaaa taaaatgaaa acgaaaaaac atagattact
    43801 tgctctagct cttatttcaa attttacatt attgggagct gcatcagctg ctgtacaata
    43861 tccagatgga ggagtatgga catatggaga aggttcagga ggtggttagg ctttttcaaa
    43921 ttactatcat ggtaaaaaat atcattattc atccatcgtg agcagatggg atggtcattc
    43981 tgataaagga gaagctcctg ctggaaaaac ctcctatgca tggatttgga ctaaatgggg
    44041 agaacaagta gcattttact gtgattatga ctaatcgttc attgatttaa atcgttcccc
    44101 ttgtaagaaa ttacaggggg aattttgttt acaaggagtc tactatgaag aaactattca
    44161 tattattatc aacttttttt ctcagcttct tccttgcttg gattattgtc ttacgtgcgc
    44221 cacaatattt atatgcaagc tatgattccg tttctttact tcgtgtcaaa aaagatactc
    44281 aggaaccgac gcgtgaggta tttgaacagg aattggagaa ttttgcaaac tcagaacaga
    44341 gtttaatagc tagaagaatt gtagagccga gtaaggatgg gacgactcac tttacttatg
    44401 caacttatgg tcagggaact ttaccaaaag aattccaaga agctagccaa gaaagtcgtg
    44461 aacgtagtga tccgctaaat agttatctcc ttttgtcagg ctccttgacg aaagaaaagc
    44521 ttgccgataa attaggagat ttgggttata aagcaagtgc tgaccgaaag ataccgccct
    44581 attttcttgc ttttcgaata ttactaaatc cccttatttt aattagttta gcaatatttg
    44641 gtttatcttt ctttgcttta gtgattatca ctcggattaa ggaaatgaga gcagcaggta
    44701 taaaactctt ttctggtcag actctcttat ccatcatggg gcattcttta tctactgata
    44761 tcaaatggct ccttctatca gccctccttt ccttcctagg tgggggagtc gttcttttta
    44821 gtcaaggttt gttttatcct atcttgttag ccacctatgg ttttgggatt agtttctatc
    44881 tgttgttttt attggcgatt tcaattttac taatgcttct ttatctaatg agtttgaatt
    44941 acaaagcatt agttcccgtt attaagggga gattacccct taaacgcctg atgattttaa
    45001 ccctattgtg tcagttggtt gctgtcttta cagtaggata cgctgttaag acaggtttga
    45061 cgtcttacca acgattgaaa gaacttgaaa tttcaaaaca agcatggcag gatagagcag
    45121 actattatca aatttctttt ggcttaggtg atagaggaaa agatacagaa aatcagagca
    45181 agtggtatgc ctttgccaag gaagcaatcg aagaagaaca agctctttat gtaaaggata
    45241 atctgctcca ttttgccaat ccacaaggaa aaaatgaaca gggagagaca ctggatacct
    45301 atagtccaga tgctaatacg ctctatgtta gtcccagtta tttggacaag gaaaaggtcg
    45361 tggtagatgc tgagaccaaa cagaagttag cccatctcca aaaaggtgag tttatcctct
    45421 tgctcccaga acatttgcgc tctcgagaag cagaacttaa gaaagttttt gaagaaagat
    45481 tgagttatta tggaaaatct ggtgaggagg caagtgctcc tttggattat gagatgaaag
    45541 cgcacgttag ttatctttca atgggagaaa agcggtttgt ttataataac ggtgagaatc
    45601 ccgtatccac tcagtatttg attgatccga ttttagttgt attcacgccg acttctacag
    45661 gtgatagttt tatatcctta tctagttggt ctatcaatgc tggaaaacaa ctctttatca
    45721 aaggatatga gagtgggcta gaactcttga agaaagctgg aatttatgag caagtatcct
    45781 atcttaaaga aggaagaagt gtttatctaa ctcgttataa tgaagttcaa actgaaacag
    45841 caactttaat cttaggagct attgtgggga tagctagttc cttgttacta ttttattctg
    45901 tcaatcttct atatttcgag caattccgcc gagatatttt gattaaacga atttcaggtt
    45961 tacgattttt tgaaacacat gctcagtata tggttagtca atttgccagt tttgtatttg
    46021 gtgctagtct ctttatttta agcagtcgag acttggtgat tggcttgctc actttattag
    46081 tctttctagc tagtgcagtt ctgacgcttt accgtcaagc gcagaaagaa tctcgtgttt
    46141 ctatgacaat tatgaaagga aaataggatg attgaactaa agaatatatc taaaaaattt
    46201 ggaagccgtc agctattttc agatacaaat cttcattttg aaggtgggaa aatttatgcc
    46261 ttaatcggta caagtggctg tggtaagaca acactcttga atatgattgg acgattagag
    46321 ccatatgaca aagggcaaat catctatgat ggcacttctc ttaaggacat caagccttct
    46381 gttttcttta gagattactt gggatactta tttcaagatt ttggcttaat tgaaagccaa
    46441 accgtcaaag agaatctcaa tctgggttta gttggtaaaa agttgaagga aaaagagaaa
    46501 atctctttga tgaaacaagc tctaaaccgt gtaaacctct cttatttgga tttgaagcaa
    46561 cctatatttg agttatcagg aggagaagca caacgtgttg cattagcgaa gataatttta
    46621 aaggatccgc ctttgattct tgcagatgaa ccaaccgctt ccttagaccc caaaaactct
    46681 gaggaattac tttccatcct agaatcttta aaaaatccga atcggaccat tattattgcg
    46741 acccacaatc ctctgatttg ggagcaagtg gatcaggtca ttcgagttac cgatttatca
    46801 catagataat atggtaagat tcagttagaa gaaagagtca caaacacact ttgtggcttt
    46861 tttatttcca taaaaatggt aaaatagtag gagtagaaat ggagttcgag acatgaaagt
    46921 aatagatcaa tttaaaaata agaaagttct tgttttaggt ttggccaagt ctggtgaatc
    46981 tgcagctcgt ttgttggata agctaggcgc catagtgaca gtaaatgacg ggaaaccatt
    47041 cgaggacaat ccagctgccc aaagtttgct ggaagaaggg atcaaggtca ttacaggtgg
    47101 ccatcctttg gaactcttgg atgaagagtt tgcccttatg gtgaaaaatc caggtatccc
    47161 ctacaacaat cccatgattg aaaaggcttt ggccaaggga attccagtct tgactgaggt
    47221 ggaattggct tatttgattt cagaagcacc gattattggt atcacaggat cgaacggtaa
    47281 gacaaccaca acgactatga ttggggaagt tttgactgct gctgggcaac atggtctttt
    47341 atcagggaat atcggctatc cagctagtca agtggcccaa actgcgtcgg acaaggacac
    47401 gcttgttatg gaactttctt ctttccaact catgggtgtt caagaatttc atccagagat
    47461 tgcggttatt actaacctta tgccaactca tatcgattat catggattat ttgaggaata
    47521 tgtagcagcc aagtggaata tccagaacaa gatgacagca gctgatttcc ttgtcttgaa
    47581 ctttaatcaa gacttggcaa aagacttgac ttccaagaca gaagccactg ttgtaccatt
    47641 ttcaacactt gaaaaggttg atggagctta tctggaagat ggtcaactct acttccgtgg
    47701 tgaagtagtc atggcagcga atgaaatcgg tgttccaggt agccacaatg tggaaaatgc
    47761 ccttgcgact attgctgtag ccaagcttcg tggtgtggac aatcaaacca tcaaggaaac
    47821 tctttcagcc ttcggtggtg tcaaacaccg tctccagttt gtggatgaca tcaagggtgt
    47881 taaattctat aacgacagta aatcaactaa tatcttggct actcaaaaag ccttgtcagg
    47941 atttgacaac agcaaggtcg tcttgattgc aggtggtttg gaccgtggca atgagtttga
    48001 cgaattggtg ccagatatta ctggactcaa gaagatggtc atcctgggtc aatctgcaga
    48061 acgtgtcaaa cgggcagcag acaaggctgg tgtcgcttat gtggaggcga cagatattgc
    48121 agatgcgacc cgcaaggcct atgagcttgc gactcaagga gatgtggttc ttcttagtcc
    48181 tgccaatgcc agctgggata tgtatgctaa ctttgaagta cgtggcgacc tctttatcga
    48241 cacagtagcg gagttaaaag aataaaatat gaaaaaaatt gtctttacag gtggggggac
    48301 ggttggacac gttaccctca atcttttgtt aatgcccaag ttcatcgaag atggttggga
    48361 agtccactat atcggggaca agcgtggtat cgaacaccaa gaaatcctta agtcaggttt
    48421 ggatgtcact ttccactcca ttgcgactgg gaaattgcgt cgctatttct cttggcaaaa
    48481 tatgctggac gtcttcaaag ttggctgggg aatcgtccaa tcgctcttta tcatgttgcg
    48541 acttcgtcca cagacccttt tttcaaaggg gggctttgtc tcagtaccgc ctgttatcgc
    48601 tgcgcgtgtg tcaggagtgc ctgtctttat tcacgaatct gacctgtcta tgggcttggc
    48661 caataaaatc gcctataaat ttgcgactaa gatgtattca acctttgaac aagcttcgag
    48721 tttggctaag gttgagcatg tgggagcagt gaccaaggtt tcagatcaaa aaaatccaga
    48781 accagatgaa ttggtggata ttcaaagcca ctttaatcat aaattgccga ctgtattgtt
    48841 tgttggcggt tctgcaggtg ctcgtgtctt taaccaattg gtgacagacc ataaaaaaga
    48901 actaacagag cgctacaata ttatcaatct aactggagat tctagcctga atgagttgag
    48961 ccaaaatctt tttcgtgttg actatgtgac cgatctctat caacccttga tggaattggc
    49021 tgatattgtt gtgacacgtg gtggtgccaa tacgattttt gagctcttgg cgatagcaaa
    49081 attgcatgtc attgtgccgc ttggtcgtga agctagtcgt ggtgaccaga ttgaaaatgc
    49141 agcttacttt gttaagaaag gctatgcaga agaccttcaa gaaagcgatt tgaccttgga
    49201 tagtttggaa gagaagcttt ctcacttact aagtcacaag gaagattacc aagctaagat
    49261 gaaagcttct aaggaattga aatctctagc agatttttat caattgttga aaaaagattt
    49321 atcataagga aagtaaatgt caaaagataa gaaaaatgag gacaaagaaa ccctcgaaga
    49381 attgaaagag ttatcagaat ggcagaaacg aaaccaagaa tatctaaaaa agaaggctga
    49441 agaagaggcg gctctagctg aggagaagga aaaggaaaga caagctcgaa tgggagaaga
    49501 atctgagaag tcagaggata aacaggacca ggagagtgaa acagaccaga aagattcaga
    49561 atcagctaag gaagagtctg aagaaaaagt agcatcctca gaggctgaca aagagaaaga
    49621 agagaaagaa gaaccagagt ctaaagagaa ggaggaacag gataaaaagc ttgctaaaaa
    49681 ggctacaaag gaaaaaccag ccaaagcaaa gattcctggt atccatatct tgcgagcctt
    49741 cacgatttta tttccaagtc tgcttttatt gattgtctct gcctacttgc tcagtcctta
    49801 tgcgaccatg aaagatattc gtgttgaggg aacggtgcaa actacagctg atgatattcg
    49861 acaggcttca ggcattcagg attcggatta tacgattaac cttctgctag acaaggcaaa
    49921 atatgaaaag cagattaagt ctaactattg ggttgaatca gctcaacttg tctatcaatt
    49981 tccaactaag ttcactatta aggtcaagga atatgatatt gtggcctact atatttctgg
    50041 tgaaaatcat tatcctattc tttccagtgg tcagcttgag actagttctg tgagtctgaa
    50101 cagtttacca gaaacttatt tatcagttct ctttaatgat agtgaacaaa tcaaggtttt
    50161 tgtctcagaa cttgctcaaa ttagcccaga actcaaggcg gctatccaaa aggtggaatt
    50221 agccccaagc aaggtgacat ccgatttaat tcgattgacc atgaatgatt cggacgaagt
    50281 cttggttcct ctatctgaaa tgagtaagaa actgccatat tacagtaaga ttaagccaca
    50341 attgtcagaa ccgagtgtga ttgacatgga agctggagtc tacagctaca ctgtagcgga
    50401 taaattgatt atggaagcag aagaaaaagc taaaaaagag gccgaagaag ctgagaaaag
    50461 gcaggaagag gaacgtaaac gtttagaaga agaacagaaa aaacaagagg aagagagcaa
    50521 tcgaaaccaa acgacccagc gctcatcgcg tcgctaggtt ttaccttttc tcctatagct
    50581 ctttagttgc catgttttta cgtttaatat ttgacatctg tttttcttta tgttacattt
    50641 gcaatgtaat cgattacaaa aaaatttttt atgaagaagg taacacatat gtcagatgaa
    50701 gtattcttat ttgaagaaat tgaagaaatc gtagccccta cagatggtga attttggggg
    50761 ggagttttac ttggaactgg ggtagttctc ttaattggag tagcctgttg ttaaaaagat
    50821 agggagtgat aatcatgcaa gataactttt tatttgagga aattgaagaa atttcagtac
    50881 cagttagtga tttttcagct ggacttgcaa caggtatcgg atttggttta gcaatccttg
    50941 ctcttgctgg ttgttgaagt ttgttcactt actaatatca agctttttca atttagacag
    51001 tcatttgaat tttccgtatt agtcttgcag caagagatta atagaattag tcattatttt
    51061 attgattgcg gactgaggga ctagagtatg ttttacttag cccctctttt atttattaaa
    51121 ggttaggttt gttatgagaa ttgttgataa gattaagata ttacctactc cttatgaggg
    51181 acagtatcat ctatatatac catccagtaa gaaacatgta ttagttggga aacaggaaaa
    51241 aaatggttag agcaactaat aggtcaagaa tttaccatat cggacttatt agtgttagta
    51301 gggaagaaat attatttaag
//
LOCUS       DAVKUR010000008        48823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKUR010000008 DAVKUR010000000
VERSION     DAVKUR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.008"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VW749_000548"
     CDS             complement(<1..137)
                     /locus_tag="VW749_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0174637.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            314..1759
                     /gene="cps4A"
                     /locus_tag="VW749_000549"
     CDS             314..1759
                     /gene="cps4A"
                     /locus_tag="VW749_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0174638.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVITALVLLVALLGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAVYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1761..2492
                     /locus_tag="VW749_000550"
     CDS             1761..2492
                     /locus_tag="VW749_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0174639.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKVKELFVDNPRKIIMDQLI"
     gene            2501..3193
                     /gene="cpsC"
                     /locus_tag="VW749_000551"
     CDS             2501..3193
                     /gene="cpsC"
                     /locus_tag="VW749_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0174640.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSMTRIYVVNRNQGEKSGLTNQDLQAGSSLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLHMT
                     LLGIVPNLNKLK"
     gene            3203..3892
                     /gene="cpsD"
                     /locus_tag="VW749_000552"
     CDS             3203..3892
                     /gene="cpsD"
                     /locus_tag="VW749_000552"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEV0174641.1"
                     /translation="MPTLEIAQKKLEFVKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PEEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKKII"
     gene            3903..5270
                     /locus_tag="VW749_000553"
     CDS             3903..5270
                     /locus_tag="VW749_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0174642.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYVQYTSE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5274..6017
                     /locus_tag="VW749_000554"
     CDS             5274..6017
                     /locus_tag="VW749_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV0174643.1"
                     /translation="MRDRIQLLGVTIDLLTMNETIDIVEQYVLEKRPLHLMGVNADKI
                     NQCHTDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEVLQDMLKVFKRDYPNLIVIGHRNGYFSEEDEQAIQEDIREKNPDFVF
                     IGITSPKKEYIIQKFMDSGVNSVFMGVGGSFDVLSGHIQRAPLWMQKSNLEWLFRVAN
                     EPKRLFKRYFVGNISFIGRVLKAKRGVKY"
     gene            6014..6838
                     /locus_tag="VW749_000555"
     CDS             6014..6838
                     /locus_tag="VW749_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV0174644.1"
                     /translation="MNQTEMIRLIQKVELDAIKEFKKICEENDIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREAYDKLPSVFKDRIIAGKYQVLTYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSVLRKIYFGKVYWYRFLASLGTTYVGDH
                     VDMHSTKQKLIIGFFKKLGFAKLFPQNSVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDTFFKVPTEYDRYLKRLYGENYLYEEPSDDEKKSHLGGH"
     gene            6840..7718
                     /locus_tag="VW749_000556"
     CDS             6840..7718
                     /locus_tag="VW749_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0174645.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNYNAKQIVIIDNFSNNGTG
                     EKLQELYESDLEIDVLINHENAGFARGNNVAYQFAKEKYNPDFMVIMNNDIEIETENF
                     EKIVTDIYREEKFHLLGPDIFSTTYQLHQNPKRLTHYTYGEVKALNEKFKKGSQVSLA
                     LKIKCWLKASKVLRTAIYQNRRKKGSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIRVLHHQNVATNQVYTNLLEKTLFSNKCNF
                     KSTSYFLKLMKENEDV"
     gene            7719..9056
                     /locus_tag="VW749_000557"
     CDS             7719..9056
                     /locus_tag="VW749_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV0174646.1"
                     /translation="MSYLFLLCLTLFLLTIFYFFAFIQDLIAPPVVMSVMFLISSVFA
                     LVNSKNWNIEYSGIAYILIISGIIIFSLPLMALKSPNFNTEVKIADRLIDIQFWKIAL
                     TIIIDLFILYLYRKEIYNLVLSNGYTGSNIQWFFRNATSYEGELTVRTFIRVLIRVID
                     VSAYIFGYTFINNFLIYRHKRPKDILLLVPLLIFISKTLISGGRQDIIKILIAYVIMM
                     YIQQKRKVGWNRVISHKYIHLGFVGLIAGIPAFYYSLFLAGRSTTRTLFESVSTYLGG
                     SIQHFNQYIENPLDPGEVFGSETLVPILNILGEMGLVNYRSTIHLEFRTLGVTVGNVY
                     TFFRRPLHDFGLVGMYVFVFAVGAFFAIYYLVLRKKQVGFNLDIHTIIYSYVFYWIFL
                     SSIEQYSFTMISLYTLVFIVLVYFMAIFYWCTDFKRGKLIFKISDSSIKLKEE"
     gene            9079..10500
                     /locus_tag="VW749_000558"
     CDS             9079..10500
                     /locus_tag="VW749_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174647.1"
                     /translation="MNTKIKNIITSFSYVISSNLLIVLTSSLVVLIFPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYTNLDRKQFYSQMILFSSFLMLISLVLF
                     TLNLITVRDENARYIYNMAIISMIVTNLRTLYVYILQMTNRLKDSSVILISDRVLYVL
                     LLFMFIVFGWHEYKVMIWADILGRTFSLMLSFWICKDIVFQPLSKFILDFKESLDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVIFP
                     LIKRTKTENLPKIYSNLRNALMLVMFAILLFYYPLKFILDIWLPAYKDALVFMALIFP
                     MSVYEGKMALVINTYLKAMRMEKDILKINALVMLTSMVVTLVTTLLLNNLGLTVVSIV
                     ILLALRSIIAELILSKKLKISVKQDIALELLMTIIFISSSWYLSIWIAVIIYLLAYTL
                     YLYLKHKDIRMYIEYFKNHKKIS"
     gene            10564..11652
                     /gene="wecB"
                     /locus_tag="VW749_000559"
     CDS             10564..11652
                     /gene="wecB"
                     /locus_tag="VW749_000559"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV0174648.1"
                     /translation="MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMV
                     SPVLDLFGVQPDYDLEIMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKE
                     GRNNIYVTGNTVIDALTTTVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYDDVKVIYPIHKNPLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPE
                     EYKKMSQASNPYGNGDASKQIVRILRGI"
     gene            11691..12560
                     /gene="rfbA"
                     /locus_tag="VW749_000560"
     CDS             11691..12560
                     /gene="rfbA"
                     /locus_tag="VW749_000560"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0174649.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12561..13157
                     /locus_tag="VW749_000561"
     CDS             12561..13157
                     /locus_tag="VW749_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0174650.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            13167..14216
                     /gene="rfbB"
                     /locus_tag="VW749_000562"
     CDS             13167..14216
                     /gene="rfbB"
                     /locus_tag="VW749_000562"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0174651.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14282..15133
                     /gene="rfbD"
                     /locus_tag="VW749_000563"
     CDS             14282..15133
                     /gene="rfbD"
                     /locus_tag="VW749_000563"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0174652.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15209..15643
                     /locus_tag="VW749_000564"
     CDS             15209..15643
                     /locus_tag="VW749_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174653.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAENQVITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            15716..15973
                     /locus_tag="VW749_000565"
     CDS             15716..15973
                     /locus_tag="VW749_000565"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174654.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLMEDFFA"
     gene            16019..16165
                     /locus_tag="VW749_000566"
     CDS             16019..16165
                     /locus_tag="VW749_000566"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174655.1"
                     /translation="MEYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQW
                     TLLA"
     gene            16236..16394
                     /locus_tag="VW749_000567"
     CDS             16236..16394
                     /locus_tag="VW749_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0174656.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            16593..18575
                     /locus_tag="VW749_000568"
     CDS             16593..18575
                     /locus_tag="VW749_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0174657.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDGYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVMAPVNEEFLNSKGDDFAKATDPNSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            18875..24193
                     /locus_tag="VW749_000569"
     CDS             18875..24193
                     /locus_tag="VW749_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0174658.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVFYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMMEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(24360..26519)
                     /locus_tag="VW749_000570"
     CDS             complement(24360..26519)
                     /locus_tag="VW749_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0174659.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VW749_000571"
     CDS             complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VW749_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0174660.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            27178..27705
                     /locus_tag="VW749_000572"
     CDS             27178..27705
                     /locus_tag="VW749_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0174661.1"
                     /translation="MATALVLGYSTFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            27775..28104
                     /gene="gpsB"
                     /locus_tag="VW749_000573"
     CDS             27775..28104
                     /gene="gpsB"
                     /locus_tag="VW749_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0174662.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            28125..28505
                     /gene="rnpB"
                     /locus_tag="VW749_000574"
     ncRNA           28125..28505
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VW749_000574"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            28590..29747
                     /locus_tag="VW749_000575"
     CDS             28590..29747
                     /locus_tag="VW749_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0174663.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFDEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            29760..31154
                     /gene="mapZ"
                     /locus_tag="VW749_000576"
     CDS             29760..31154
                     /gene="mapZ"
                     /locus_tag="VW749_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0174664.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            31230..32654
                     /gene="gndA"
                     /locus_tag="VW749_000577"
     CDS             31230..32654
                     /gene="gndA"
                     /locus_tag="VW749_000577"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0174665.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            32666..33355
                     /locus_tag="VW749_000578"
     CDS             32666..33355
                     /locus_tag="VW749_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0174666.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            33453..34415
                     /gene="cbpC"
                     /locus_tag="VW749_000579"
     CDS             33453..34415
                     /gene="cbpC"
                     /locus_tag="VW749_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0174667.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            34434..35432
                     /gene="cbpJ"
                     /locus_tag="VW749_000580"
     CDS             34434..35432
                     /gene="cbpJ"
                     /locus_tag="VW749_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0174668.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(35550..36782)
                     /locus_tag="VW749_000581"
     CDS             complement(35550..36782)
                     /locus_tag="VW749_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0174669.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(36941..37411)
                     /locus_tag="VW749_000582"
     CDS             complement(36941..37411)
                     /locus_tag="VW749_000582"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174670.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(37311..37649)
                     /locus_tag="VW749_000583"
     CDS             complement(37311..37649)
                     /locus_tag="VW749_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV0174671.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            38312..38590
                     /locus_tag="VW749_000584"
     CDS             38312..38590
                     /locus_tag="VW749_000584"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174672.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
     gene            38765..39643
                     /gene="mvk"
                     /locus_tag="VW749_000585"
     CDS             38765..39643
                     /gene="mvk"
                     /locus_tag="VW749_000585"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0174673.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            39625..40578
                     /gene="mvaD"
                     /locus_tag="VW749_000586"
     CDS             39625..40578
                     /gene="mvaD"
                     /locus_tag="VW749_000586"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0174674.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            40565..41572
                     /locus_tag="VW749_000587"
     CDS             40565..41572
                     /locus_tag="VW749_000587"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0174675.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            41556..42566
                     /locus_tag="VW749_000588"
     CDS             41556..42566
                     /locus_tag="VW749_000588"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0174676.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            42644..43342
                     /locus_tag="VW749_000589"
     CDS             42644..43342
                     /locus_tag="VW749_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0174677.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            43339..44334
                     /locus_tag="VW749_000590"
     CDS             43339..44334
                     /locus_tag="VW749_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0174678.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            44348..44980
                     /locus_tag="VW749_000591"
     CDS             44348..44980
                     /locus_tag="VW749_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0174679.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            44981..45223
                     /locus_tag="VW749_000592"
     CDS             44981..45223
                     /locus_tag="VW749_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0174680.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            45148..45459
                     /locus_tag="VW749_000593"
     CDS             45148..45459
                     /locus_tag="VW749_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0174681.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLT
                     S"
     gene            45484..45750
                     /locus_tag="VW749_000594"
                     /pseudo
     CDS             45484..45750
                     /locus_tag="VW749_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            45900..46139
                     /locus_tag="VW749_000595"
     CDS             45900..46139
                     /locus_tag="VW749_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174682.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            46220..47041
                     /gene="cbpG"
                     /locus_tag="VW749_000596"
     CDS             46220..47041
                     /gene="cbpG"
                     /locus_tag="VW749_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0174683.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            47060..48082
                     /gene="cbpF"
                     /locus_tag="VW749_000597"
                     /pseudo
     CDS             47060..48082
                     /gene="cbpF"
                     /locus_tag="VW749_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(48210..48823)
                     /locus_tag="VW749_000598"
                     /pseudo
     CDS             complement(48210..48823)
                     /locus_tag="VW749_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        15229 a         8301 c        10713 g        14580 t
ORIGIN      
        1 tttcctttct gttgataggc tagtagcaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatta aagatgcaga
      241 tagtaaaaaa aatgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaaggt
      301 ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag tgaagcgaag
      361 tgttaatatc gttttgctga ctatttattt attgttagtt tgttttttat tgttcttaat
      421 ctttaagtac aatatccttg cttttagata tcttaaccta gtgataactg cgttagtcct
      481 actagttgcc ttgctagggc tactcttgat tatctataaa aaagctgaaa agtttactat
      541 ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt
      601 tgttggactg actaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt
      661 cgctgtttta gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc
      721 gactgggact gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa
      781 taccgatttg acggtcaacc agagttcgtc ttacttggca gtttacaaga gtttgattgc
      841 aggggagact aaggccattg tcctaaatag tgtctttgaa aacatcatcg agtcagagta
      901 tccagactac gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga
      961 agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta
     1021 tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga
     1081 taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa tcgcagatgg
     1141 tggaaataat caaaaagata aattaaccca tgcaggcatt tatggagttg attcgtccat
     1201 tcacacctta gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac
     1261 ttctttcttg aaaatgattg acttattggg aggggtagat gttcataatg atcaagagtt
     1321 ttcagctcta catgggaagt tccatttccc agtagggaat gtccacctag actctgagca
     1381 ggctctaggt tttgtacgtg aacgctactc actagccgat ggagaccgtg atcgtggtcg
     1441 caaccaacaa aaggtcattg tagcaattat tcagaagtta acttctacag aggttttgaa
     1501 aaactatagt agtattcttc aaggattgca ggattctctt caaacaaata tgccgattga
     1561 gactatgata gatttagtga atactcagtt ggaaagtggg gggaattata aagtaaattc
     1621 tcaagattta aaagggacag gtcggatgga tcttccttct tatgcaatgc cagacagtaa
     1681 cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga
     1741 tgtgatggag ggtagatgaa atgatagaca tccattcgca tatcgttttt gatgtagatg
     1801 acggtcccaa gtcaagagag gaaagcaagg ctctcttggc agaatcctac aggcaggggg
     1861 tgcgaaccat tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga
     1921 agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtggca gatgatttag
     1981 tcattgctta tggcgcagag atatactata ctctggatgc tctagaaaag ctagaaaaaa
     2041 aagaaattcc tacccttaat gatagtcgtt atgccttgat tgagtttagc atgcatactt
     2101 cctatcgtca gattcatacg ggattgagca atattttgat gttgggaatc acgccagtaa
     2161 ttgctcatat tgaacgttat gatgctttag agaataacga aaaacgtgtt cgtgaactga
     2221 ttgatatggg gtgctatact cagataaata gttatcatgt ttcaaaacct aagttctttg
     2281 gtgaaaaata taaattcatg aaaaagagag ctcggtattt tttggaacgt gatttagttc
     2341 atgtagttgc aagtgacatg cacaatttag acagtagacc tccatatatg caacaggcat
     2401 atgatatcat tgctaagaaa tatggagcga aaaaagtaaa agaacttttt gtagataatc
     2461 ccagaaaaat tataatggat caattaattt aggagaaaat atgaaggaac aaaacacttt
     2521 ggaaatcgat gtattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt
     2581 agtggcaatt ataacttctt cagttgcttt tgcctacagt acttttgtta tcaaacctga
     2641 gtttactagt atgactcgga tttatgtagt taaccgtaat cagggagaga agtctggttt
     2701 aaccaatcaa gacttgcagg caggatcatc cttggttaaa gactatcgtg aaattatcct
     2761 atcgcaggat gttttggagg aagttgtttc tgatttgaaa ctagatttga cgccaaaaga
     2821 tttggctaat aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt
     2881 tagtgatcga gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc
     2941 tcaaaaaatt atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc
     3001 ggcgacatca ccgtcttcgc caaatattaa acgcagtaca ctaattggtt ttttggcagg
     3061 agtgattgga actagtgtta tagttcttat tcttgaactt ttggacactc gtgtgaaacg
     3121 tccgaaagat atcgaagata cactgcatat gacacttttg ggaattgtac caaacttgaa
     3181 taagttgaaa taggagagag gaatgccgac attagaaata gcacaaaaaa aactggagtt
     3241 cgttaagaag gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga
     3301 taaactaaaa gtaatttccg ttacttctgt taaccctgag gaaggaaaaa caactacttc
     3361 cgtaaatata gcaaggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga
     3421 tactcgaaat tcagttatgt caggattttt taaatctcgt gaaaaaatta cagggctaac
     3481 ggaattttta tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa
     3541 tttatttgta gttcaatcgg gcactgtatc accaaaccct acagccttgt tacaaagtaa
     3601 aaattttaat gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac
     3661 agcacctatt ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat
     3721 cttggtaaca gcaacaggtg aggtgaataa acgtgatgtc caaaaagcga aacaacaatt
     3781 agaacaaaca gggaaactgt tcctaggagt tgttttgaat aaattagata tctcggttga
     3841 taagtatgga gtttacggtt tctatggaaa ttatggtaaa aaaataattt aggaaagatt
     3901 ctatggatga aaaaggattg aaaatttttt tggcagtatt acagagtatt attgtcattt
     3961 tattggttta ttttcttagc tttgttagag agacagaact tgaacgttct tcgatggtta
     4021 tactatacct tctccacttt tttgtattct attttagttc ctatggtaac aattttttta
     4081 aaagagggta cctagttgag tttaatagta ccataagata tatttttttc tttgcaatag
     4141 ctataagtgt attaaacttt tttatagcgg aacggtttag tatctctaga agaggaatgg
     4201 tatacttctt aactttagaa ggaatatcct tatacttgtt aaatttctta gtaaagaaat
     4261 attggaagca tgtgtttttt aatctaaaaa atagcaagaa aattttactg ttaacagtaa
     4321 cgaaaaatat ggaaaaagtt cttgataaat tgctagaatc tgatgaactt tcatggaaat
     4381 tggtagcagt aagtgttttg gataaatctg attttcaaca tgataaaata cctgtaattg
     4441 aaaaggaaaa aattattgaa tttgcaacgc atgaagttgt ggatgaggtg tttgtcaatc
     4501 ttccaggaga gagctacgat attggagaaa ttatctctag gtttgagaca atggggatag
     4561 atgtaactgt aaatcttaaa gcatttgata agaatttggg tcgcaataaa caaattcatg
     4621 agatggtagg attgaatgta gtcactttct ctacaaattt ttataaaact agtcatgtaa
     4681 ttgctaagcg gattattgat atcatgggtg cattggtagg gctgatacta tgtggtttag
     4741 tcagtattgt attggttcct ttgattcgaa aggatggggg ctctgctatt tttgctcaga
     4801 cgcgtatagg aaaaaatggt cgtcagttca ctttttataa gtttcgctct atgtgtgtag
     4861 atgccgaggc gaaaaaaaga gaactcatgg aacaaaatac catgcagggt ggaatgttta
     4921 aggtggacga tgatcctcgt atcacgaaaa ttggtcgttt tatacggaag actagcttgg
     4981 acgagttacc acagttttat aatgttctaa agggagatat gagtttggtt ggcacacggc
     5041 cacctacagt ggacgagtat gttcagtata cttcagaaca gaaacgtcga ctcagcttta
     5101 aacctggtat tacaggttta tggcaggtta gcggccgtag taaaataacc gattttgacg
     5161 atgttgtaaa attagatgtg gcttatattg ataattggac aatctggaaa gatattgaaa
     5221 ttttgcttaa aactgttaaa gttgtattta tgagagatgg agcgaagtga ggaatgaggg
     5281 atagaatcca acttttaggt gtaacaattg atttgcttac gatgaatgaa acgatagata
     5341 ttgtagaaca atatgtatta gaaaaaagac cactacactt gatgggggtg aatgctgata
     5401 aaattaatca gtgtcataca gatgagaaaa tcaaaaaaat cgttaatgag tcaggaatca
     5461 ttaatgcgga tggagcatca gttgttcttg caagtaagtt tttaggaacg cctgttcctg
     5521 aacgagtagc gggtattgat ttgatgcaat gtcttttaga gttgtcaaat aaaaaaggat
     5581 attcagttta cttttttgga gcaaaagaag aagttttgca agatatgctc aaagtattta
     5641 agagagatta tccaaatttg atagttattg gacacagaaa tggctatttt tctgaagagg
     5701 atgaacaagc tattcaagaa gatattcgtg aaaagaaccc tgattttgtg tttattggaa
     5761 ttacgtctcc taaaaaagaa tatattattc aaaaatttat ggatagtggc gtcaattcgg
     5821 tatttatggg agttggcggt agttttgatg tcttgtctgg tcatatccaa cgagcacctc
     5881 tatggatgca aaagtcaaat ttagagtggt tattccgtgt agctaatgag cctaaacgtc
     5941 tctttaaacg ttattttgta gggaatattt cattcatagg aagagtttta aaagcaaaaa
     6001 gaggtgtaaa atattgaacc agacagagat gattcgctta attcaaaaag ttgaattaga
     6061 tgctataaaa gagtttaaaa aaatctgtga agagaatgat atagattttt tcctccgcgg
     6121 tggtagtgta cttggtgcgg tcaaatacga cggctttatt ccatgggatg atgatatgga
     6181 tatcgctgtc cctcgtgaag catacgacaa acttccaagt gttttcaaag atagaattat
     6241 cgctgggaaa tatcaggttc ttacttatca atactgtgat acgttgcatt gctactttcc
     6301 tcgactattc cttttagaag atgaaagaaa acgtttgggc ttgccacgaa ataccaatct
     6361 aggattgcat ttgattgata tcattccttt agatggagca ccaaatcatt cggttttaag
     6421 aaagatttac tttggcaaag tatactggta tcgtttttta gcaagtttag gaacaactta
     6481 tgttggcgac catgtggata tgcattccac taagcaaaaa ctaattattg gtttctttaa
     6541 aaaactagga tttgcaaaac tatttcctca aaattctgta tacagacgct tggataatct
     6601 ctataaaaag tatgattgga aaaagcagaa gtatgcgggg actatcaatg cttctttatt
     6661 tgctaaagaa gttatgccag tagagatttg gggagaagga gtagagaagc cttttgagga
     6721 tactttcttt aaagttccaa cggagtatga tcgctacctg aaaagacttt acggagaaaa
     6781 ctatctttac gaagagccta gtgatgatga aaagaaatcg catttaggag gacactaatt
     6841 tgttttgtta tattattttg cattacaaag tcttagaaga aactatttct tgtgttaaat
     6901 ctataaaaga aggcaattat aatgcaaagc aaatcgttat tattgataat ttttctaata
     6961 atggtactgg tgaaaaacta caagagcttt atgaatcaga tttagaaatt gatgttttga
     7021 ttaaccatga aaatgctggt tttgctcgtg gaaataatgt ggcttatcaa tttgctaagg
     7081 aaaagtataa ccccgatttc atggttatca tgaataacga tattgagata gaaacagaaa
     7141 attttgaaaa aattgtgaca gatatctatc gtgaggaaaa attccatttg ctcgggccag
     7201 atatcttctc gactacttac caacttcacc aaaacccaaa acggttgaca cattatactt
     7261 atggagaagt taaagctcta aatgaaaaat ttaaaaaagg gagccaagtt agtctagctt
     7321 taaaaatcaa atgttggttg aaagctagta aagttcttcg aacagcaatc tatcaaaata
     7381 gacgtaaaaa aggatcagta gactatagaa aacaggtaga aaacccaatt cttcatggtt
     7441 cttttattgt atattcgaga gattttatcg aaaaagagga gtatgctttt aaccctaaca
     7501 ccttcttcta ctatgaaaca gagatattag attatgaagc tgaattaaaa ggatacaaga
     7561 gaatttatac acctaaaatt agagttttgc accatcaaaa tgttgcaact aatcaagttt
     7621 acacgaactt gttagaaaaa accttgtttt caaataaatg caactttaaa tccaccagtt
     7681 attttttgaa gttgatgaaa gaaaacgagg atgtttaaat gagttattta tttttacttt
     7741 gccttacatt attcttattg actatattct atttctttgc ttttattcaa gatttaattg
     7801 ctcctccagt agttatgtct gtaatgtttc taattagttc agtatttgca ctggttaatt
     7861 caaaaaactg gaatattgaa tatagtggaa tagcctatat tctcataatt agtggtatta
     7921 ttatattttc gcttccttta atggcattaa aatcacctaa ttttaatact gaggttaaga
     7981 ttgctgatcg attaattgat atccaatttt ggaaaattgc tctaactatt ataattgatc
     8041 tctttatttt gtatctttac aggaaggaaa tatataacct tgttcttagt aatggatata
     8101 cggggtcaaa tattcagtgg ttttttagaa atgcaacgag ttatgaaggt gaattgacag
     8161 tgcgaacttt tattcgagtt ctcattcgtg ttattgacgt atctgcttat atttttggat
     8221 atacttttat taataatttt cttatctatc gccataaacg ccctaaagac atattacttt
     8281 tagtaccttt attaatattt atttcaaaaa ctttaatatc aggaggccgg caagatatta
     8341 ttaaaattct gattgcctat gtaatcatga tgtatatcca acaaaaacgg aaagttggat
     8401 ggaatagagt catatctcat aaatatattc accttggatt tgttggttta atagcaggta
     8461 ttccagcatt ttactactct ttgtttttag ccggtcgttc aacgactagg acgctatttg
     8521 agagtgtttc gacctatcta ggaggctcaa ttcagcattt taatcagtat attgaaaatc
     8581 cattagatcc tggtgaagtt tttggcagtg aaacattggt gcctatatta aatatattag
     8641 gggaaatggg cctagttaat tatcgtagta caattcattt agaatttcgg acactaggag
     8701 ttactgtagg aaatgtttat acttttttta gaagaccctt gcatgatttt ggtctagttg
     8761 gtatgtatgt gtttgtcttt gctgtaggtg ctttttttgc tatttattat ttagttctga
     8821 gaaagaaaca ggttggtttt aatttggata ttcataccat tatttattct tatgtctttt
     8881 attggatttt tttatcatca atcgagcaat actcgttcac aatgattagt ctatatacac
     8941 ttgtatttat tgtgttggtt tactttatgg ctatctttta ctggtgtaca gattttaaaa
     9001 gaggaaaact gatttttaaa atttctgact caagtatcaa attaaaagaa gaataacaga
     9061 atgtatagga gagggtagat gaatactaaa attaaaaata taataactag tttttcttat
     9121 gttatttctt caaatctgct catagtttta acctcatcac tagttgtttt gatttttcct
     9181 aaaataatgg gggtaactga gtacagttac tggcaacttt atatttttta tctgacctat
     9241 atcggttttt tccacttggg ttggattgat gggatttatc tcaaatatgg tggcttagaa
     9301 tatacaaatt tagatagaaa acagttttat tctcagatga ttctattttc tagtttctta
     9361 atgctaatct cgctggtatt atttactttg aacctaataa ctgtaaggga tgaaaacgca
     9421 agatatattt ataatatggc tatcattagc atgatagtca caaacttaag aacactctat
     9481 gtttatatct tgcagatgac aaatcgcttg aaggatagtt cagtcattct aattagtgat
     9541 cgcgttttat atgtactcct tttattcatg tttattgtat ttggatggca tgagtacaag
     9601 gtcatgattt gggctgatat tctaggtcga acattttctc tcatgctttc cttctggatt
     9661 tgtaaagata ttgtgtttca gcctttgtca aaatttatct tagatttcaa ggagtccctt
     9721 gataatatcc gtgttggaat caatttaatg ctatctaaca ttgcgagtag catgattata
     9781 ggcattgttc gtatgggaat tcaatggaat tggaatattg aaacattcgg gaaagtgtca
     9841 ttaactttga gtatatctaa tttattaatg acttttatta atgccattgg attagttatc
     9901 tttcctttga taaagcgaac aaagactgag aatttaccta aaatttattc taatttaaga
     9961 aatgctttga tgttggttat gttcgcaatc ttgctcttct actatccttt aaaatttatt
    10021 cttgatattt ggcttcctgc ttataaggat gccttagttt tcatggccct aatttttcct
    10081 atgtcagttt atgaagggaa aatggctttg gtgataaata catatttaaa agcaatgaga
    10141 atggaaaaag acattctcaa aattaatgct ttggttatgt taactagtat ggtagtgaca
    10201 ttagtgacta ctctactact aaataatttg gggctgacag ttgtatctat agttatttta
    10261 cttgctttaa gaagtataat agctgaatta attttatcca aaaaactgaa gatatcagtc
    10321 aagcaagaca ttgctttaga gttacttatg acgattatat ttatttcttc aagttggtat
    10381 ctctctattt ggattgcagt aataatttat ttattggcgt atactttata tttgtattta
    10441 aagcacaaag atatcagaat gtatatagaa tactttaaaa atcataaaaa aatatcataa
    10501 aaattatata tcaatgaaat ggtagattac atttctacct ttttatccat ttaggaggaa
    10561 acgatgaaaa agataatgct agttttcggt acacgtccag aagcaataaa aatgtgttca
    10621 ttagtcaatg agttgagaaa acaggaagat atgaaaacag ttgtttgtgt aactggtcaa
    10681 cacaaggaga tggttagccc tgttttagat ttatttggag ttcaaccaga ctatgattta
    10741 gaaattatga aggctaatca aaacttgttc tctataacaa taagtatttt agaaaaaata
    10801 aaacctgtgt tagaaaaaga acaaccagat attgttttgg ttcacggtga tactactacg
    10861 acatatgcag cagctttagc ggcattttat ctaggaatta aagttggtca tgttgaagct
    10921 ggattacgaa cttacaacct gcaaagtcct ttcccagaag agttcaacag acaatcgact
    10981 tctattattg caaattatca ttttgctcct acagaattag ctaaagaaaa tctaataaaa
    11041 gagggtagaa ataatatcta tgttactgga aatacagtga ttgatgcact tacaactaca
    11101 gtacaaaagg attatacaca ccccgatcta gatttaaacg atggaaatcg cctcatctta
    11161 ttgactgctc atagacgcga aaatctcgga gaacctatga gacatatgtt tagagctgtt
    11221 aaacgagttt taaatgaata tgacgatgtt aaagtaattt atccaattca taaaaatcca
    11281 ttggtacggg aaacagctac agaaattttt ggagatacag aacgtattca gatcattgaa
    11341 cctttagatg ttcttgattt tcacaacttt atgaatcata gttatatgat tctaactgac
    11401 tcaggagggg ttcaagaaga ggcaccttcg ttaggaaagc ctgtattggt catgcgagat
    11461 acgacagaaa gacctgaagg agtagctgct ggaacgttga aattggttgg gactgatgag
    11521 gagactattt atcaaaactt taagatgctt ttagacgatc ccgaagaata taaaaaaatg
    11581 agtcaagcta gtaatcctta tggaaatggt gatgctagta aacagattgt tcgaatttta
    11641 cgtggaattt gagtgtgttc agataaagta atatagaaag gtaccctact atgaaaggta
    11701 ttattctagc aggtggttcg gggacacgtt tatatccttt gactcgcgct gcatcaaaac
    11761 aacttatgcc ggtttatgat aaaccgatga tttactaccc actttcaaca ttgatgttgg
    11821 ctgggattag ggatattttg attatttcca ctccacagga tttacatcga ttccaagagc
    11881 ttcttcaaga cggatctgag tttgggctca aactttctta tgcagagcaa ccaagtccag
    11941 atggtttggc acaagccttt atcattgggg aagagtttat ttctgatgat agcgttgcgc
    12001 tgatcttagg tgacaatatc tatcacggtt ctgggctttc caagatgcta caaaaggcag
    12061 cgagtaagga gtcgggagca actgtttttg gctaccatgt caaggatcca gagcgctttg
    12121 gtgtggttga gtttgatcag gatatgaagg ctatttctat tgaagaaaag ccagagcaac
    12181 ctcgttcaaa ctatgcagtt acaggtctct atttctatga taatgatgta gtagagattg
    12241 ccaagagtat taaaccaagt cctcgtggtg aactggaaat tacagatgta aacaaggctt
    12301 acctagatcg tggtgatttg tctgttgagc ttatgggacg tggctttgct tggctggata
    12361 ctggaactca tgaaagttta ctagaggctt cacagtacat cgaaacagtg caacggatgc
    12421 aaaatgttca ggtagcaaac ttagaagaaa ttgcttaccg tatgggctat atcagtcgag
    12481 aagatgtatt ggccttagcc caaccactta agaaaaatga atacggacag tatctgctcc
    12541 gtttgattgg agaagcatag atgacagata attttttcgg taagacgctt gcggcacgca
    12601 aggttgaagc tattccaggc atgttggagt ttgatatccc cgttcatgga gataaccgtg
    12661 gctggtttaa agaaaatttc caaaaggaaa aaatgcttcc acttggattt ccagagtctt
    12721 tctttgcaga aggaaaattg caaaacaatg tatccttctc acgtaaaaat gtccttcgag
    12781 gtctccacgc agagccttgg gataagtaca tctctgtagc agatggaggg aaagttctgg
    12841 gttcttgggt tgatctacgc gagggtgaaa cctttgggaa tacctatcag acagtgattg
    12901 atgcgagtaa gggaatcttt gttcctcgag gcgtagctaa tggctttcaa gttttatcag
    12961 atacagtgtc atatagctat ctggtcaatg attactgggc tcttgaactc aaacccaagt
    13021 atgcctttgt gaactacgct gatccaagcc ttggtattga atgggaaaat attgcagaag
    13081 cagaggtttc agaagcagac aaacatcatc cactacttaa ggatgtaaaa cctttgaaaa
    13141 aagaagattt ggaataagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg
    13201 gagctggctt tatcggttct aactttgtcc attatgttta cgagaacttt ccagatgttc
    13261 atgtgacagt cctagataag ttgacttatg ctggaaaccg cgcgaatatt gaggaaattt
    13321 taggtaatcg tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt
    13381 tggctgctca agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc
    13441 tcaatgatcc atcgccattt attcatacta acttcatcgg aacctatact cttttagaag
    13501 ctgctcgtaa gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc
    13561 tccctttacg cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg
    13621 aaacaaaata caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg
    13681 tcaaagcctg ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact
    13741 acggtcctta tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg
    13801 gtatcaagcc aaaactttac ggtgaaggta agaacgttcg tgattggatt cataccaatg
    13861 accattcttc aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga
    13921 ttggggctga tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg
    13981 gacaagctgc ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg
    14041 cgattgatgc tagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg
    14101 aagctgggct caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag
    14161 agaaagaagc tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaag
    14221 caggaaatag ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga
    14281 gatgatttta attacagggg caaatggcca attaggaacg gaacttcgct atttattgga
    14341 tgaacgtaat gaagaatacg tggcagtaga tgtggctgag atggacatta ccgatgcaga
    14401 aatggttgag aaagtttttg aagaggtgaa accgacttta gtctaccact gtgcagccta
    14461 caccgctgtt gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac
    14521 ggggacaaaa aatgtcgcaa gagcatctga aaagcatggt gcaactctag tttatatttc
    14581 tacggactat gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg
    14641 accagatcca cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa
    14701 gcatgtgtct aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa
    14761 cttcgttttt accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga
    14821 ccagtacggt cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga
    14881 aaatcgtaag gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg
    14941 gtatgatttt gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc
    15001 cagtcaattt ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc
    15061 caaagctact ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca
    15121 agaagtgaga taagtagtag aatgattttc tagtctaata aaagaggcag ataatgaact
    15181 ccaaaggagc ttaagatgta cgattatctt gttgttggtg ctggtctctt tggcgcatag
    15241 ctttggctca gtttctatta tcgctcacac catccatcag aagtttaatc tgaaggtacc
    15301 caattatcgc caagaagaag attgggctag gatgggttta ccaatcacac gtaaggaaat
    15361 ctctaattgg catatcaagg caagtcaata ctatttagag tccctttata accttttacg
    15421 agaaaagttg ttagaacaac ctcttcttca tgcggatgaa acctcttatc gggtcttaga
    15481 aagtgatagt cagctgacct actattggac ctttttgtct gggaaagctg agaatcaagt
    15541 aatcacgctt taccaccatg atcagtgtcg gagtggttcg gtagtgcaag aattcctagg
    15601 agattattct ggctatgtgc attgtgatat gttgcggcag taacttagga ctttagtcct
    15661 ctagttctgt ctatgcgata gcagtccaag gtttaggagc aaggcgacgc taagcttggt
    15721 aaactgcgaa ccgctagaag cttatcgtca actggaagaa gctgaacttg ttggatgttg
    15781 ggcgcatgtg agaaggaaat tttttgaagt gccccccaag caagcagata aatcatcctt
    15841 aggagctaaa ggtttagctt attgtgatca gttattttcc ttggaaagag actgggaggc
    15901 tttgccagct gatgaacgac tacagaaacg tcaagaacat ctccaacccc taatggaaga
    15961 cttctttgct tagtgccgtc gtcagtcagt tttatcgggt tcaaaactag gaagggcaat
    16021 tgaatacagc ctcaagtatg aagaaacctt taagaccatt ttaaaagacg gacatctggt
    16081 cctttccaat aatctagctg aacgcgccat taaatcattg gttatgggac ggagtaaaag
    16141 agtccagtgg actcttttag cctaagctaa attttaaaaa gcgagggtgg ttattttctc
    16201 aaagttttga aggagctaaa gcaagagcta ttattatgag cttattggaa acagctaaac
    16261 gtcatcaact aaatagtgag aaatatctat cctatcttct agaatgtctt ccaaacgagg
    16321 aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa gttgtacaag
    16381 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact aatctggaga
    16441 tttttcaata gacctcgtta ttgggcggtt acgatattca tattttttgc aaagatgttg
    16501 tttgaaaaat aattttcaaa aattctgaaa attctgttga catctttctg aaaagagtct
    16561 ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta cttgcccttg
    16621 cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca
    16681 ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt
    16741 tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag
    16801 aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg
    16861 atggattgac ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg
    16921 aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata
    16981 aaaaatcaga tgctctttac cttgttcaag aatcaatcaa aggattggat ggctatgtaa
    17041 aaggggaaat caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc
    17101 agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaacaatg ggagtaatgg
    17161 ctccagttaa tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc
    17221 caaatagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg
    17281 ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta
    17341 aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta
    17401 gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta
    17461 tgaaggacaa tattgtctat actcaacaag actctattac gtatttagtt ggtacaaata
    17521 ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag gcatcgacta
    17581 aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggtttt gatcgtacag
    17641 cctatgcctc tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg
    17701 ttccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat
    17761 tggttactta tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt
    17821 acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta caagcagaag
    17881 gtgtgacttt cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc
    17941 agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat aatgtcatta
    18001 ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg
    18061 ctgctggcga agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc
    18121 catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag
    18181 ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa
    18241 aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat gataaatacg
    18301 ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag
    18361 ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata
    18421 aaggtacaag tgaaccaatc ttatataaat acttggaact tcaagacaag gcagtcactg
    18481 tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa
    18541 aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt
    18601 tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta
    18661 ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta
    18721 cttgtttcct attgctttct cagttattat ttgttatatt aaaagtataa ttatttttat
    18781 ttatcagggt taagcattgc attttcagag gaaggagtat tttttaaaaa ggaaatgtaa
    18841 acgcttgctc aaaaatgaaa ggatttagaa gtttatgaat aaaggattat ttgaaaaacg
    18901 ttgtaaatat agtattcgga aattttcatt aggtgttgct tctgttatga ttggagctgc
    18961 attctttggg acaagtccgg ttcttgcaga tagcgtgcag tctggttcca cggcgaactt
    19021 accagctgat ttagctactg ctcttgcaac agcaaaagag aatgatgggc gtgattttga
    19081 agcgcctaag gtgggagaag accaaggttc tccagaagtt acagatggac ctaagacaga
    19141 agaagaacta ttagcacttg aaaaagaaaa accggctgaa gaaaaaccaa aagaggataa
    19201 acctgcagct gctaaacctg aaacccctaa gacggtaacc cctaagacgg taactcctga
    19261 atggcaaacg gtagagaaaa aagaacaaca gggaacagtc actatccgag aagaaaaagg
    19321 tgtccgctac aaccaactat cctcaactgc tcaaaatgat aacgcaggca aaccagccct
    19381 gtttgaaaag aagggcttga ccgttgatgc caatggaaat gcaactgttg atttaacctt
    19441 caaagaagat tctgaaaagg gcaaatcacg ctttggtgtc ttcttgaaat ttaaagatac
    19501 caataataat gtttttgtcg gttatgacaa ggatggctgg ttctgggaat acaaaactcc
    19561 aggtaatagc acatggtata aaggcaaccg tgttgctgct cctgaaacag gatcaataaa
    19621 ccgtctttct atcactctca agtcagacgg tcagctaaat gccagcaata acgatgtcaa
    19681 tctctttgac acagtgactc taccagctgc ggtcaatgac catcttaaaa atgagaagaa
    19741 gattcttctc aaggcgggct cttatgacga tgagcgaaca gttgttagcg ttaaaacgga
    19801 taaccaagag ggggtaaaaa cagaggatac ccctgctgaa aaagaaacag gtcctgaagt
    19861 tgatgatagc aaggtgactt atgacacgat tcagtctaag gtcctcaaag cagtgattga
    19921 ccaagccttc cctcgtgtca aggaatacac cttgaatgga catactttgc caggacaggt
    19981 gcaacagttc aaccaagtct ttatcaataa ccaccgaatc acccctgaag tcacttataa
    20041 gaaaatcaat gagacaacag cagagtactt gatgaagctt cgcgatgatg ctcacttaat
    20101 caatgcggaa atgacagtac gcttgcaagt tgtggacaat caattgcact ttgatgtgac
    20161 caagattgtc aaccacaatc aagtcactcc aggtcaaaag atcgatgacg aaagaaaact
    20221 actttcttct attagtttcc tcggcaatgc tttagtctct gtttctagtg atcaaactgg
    20281 tgctaagttt gatggggcaa ccatgtcaaa caatacacat gtcagcggag atgatcatat
    20341 cgatgtaacc aatccaatga aggatttggc taagggttac atgtatggat ttgtttctac
    20401 agataagctt gctgctggtg tttggagtaa ctctcaaaac agctatggtg gtggttcgaa
    20461 tgactggact cgtttgacag cttataaaga aacagtcgga aatgccaact atgtaggaat
    20521 ccacagctct gaatggcaat gggaaaaagc ttataagggc attgttttcc cagaatacac
    20581 gaaggaactt ccaagtgcta aggttgttat cactgaagat gccaatgcag acaagaaagt
    20641 tgattggcag gatggtgcca ttgcttatcg tagcattatg aacaaccctc aaggttggga
    20701 aaaagttaag gatatcacag cttaccgtat cgcgatgaac tttggttctc aagcacaaaa
    20761 tccattcctt atgaccttgg atggtatcaa gaaaatcaat ctccacacag atggtcttgg
    20821 gcaaggtgtt ctccttaaag gatatggtag tgaaggtcat gactctggtc acttgaacta
    20881 tgctgatatt ggtaagcgta tcggtggtgt cgaagacttc aagaccctaa ttgagaaggc
    20941 taagaaatat ggagctcatc taggtatcca tgttaacgct tcagaaactt atcctgagtc
    21001 taaatatttc aatgaaaaaa ttctccgtaa gaatccagat ggaagctata gctatggttg
    21061 gaactggcta gatcaaggta tcaacattga tgctgcctat gacctagctc atggtcgttt
    21121 ggcacgttgg gaagatttga agaaaaaact tggtgacggt ctcgacttta tctatgtgga
    21181 cgtttggggt aatggtcaat caggtgataa cggtgcctgg gctacccacg ttcttgctaa
    21241 agaaattaac aaacaaggct ggcgctttgc gatcgagtgg ggccatggtg gtgagtacga
    21301 ctctaccttc catcactggg cagctgactt gacctacggt ggctacacca ataaaggtat
    21361 caacagtgcc atcacccgct ttatccgtaa ccaccaaaaa gatgcttggg taggggacta
    21421 cagaagttat ggtggtgcag ccaactatcc actgctaggt ggctacagca tgaaagactt
    21481 tgaaggctgg caaggaagaa gtgactacaa tggctatgta actaacttat ttgcccatga
    21541 cgtcatgacc aagtacttcc aacacttcac tgtaagtaaa tgggaaaatg gtacaccggt
    21601 gactatgacc gataacggta gcacctataa atggactcca gaaatgcgag tggaattggt
    21661 agatgctaac aataataaag tagttgtaac tcgtaagtca aatgatgtca atagtccaca
    21721 atatcgcaaa cgtacagtaa cgctcaacgg acgtgtcatc caagatggtt cagcttactt
    21781 gactccttgg aactgggatg caaatggtaa gaaactttct actgataagg aaaagatgta
    21841 ctacttcaat acgcaggccg gtgcaacaac ttggaccctt ccaagtgatt gggcaaagag
    21901 caaggtttac ctttacaagc taactgacca aggtaagaca gaagagcaag aactaactgt
    21961 aaaagatggt aaaattaccc tagatcttct agcaaatcaa ccatacgttt tctatcgttc
    22021 gaaacaaacc aatcctgaaa tgtcatggag tgaaggcatg cacatctatg atcaaggatt
    22081 taatagcggt accttgaaac actggaccat ttcaggcgat gcttctaagg cagaaattgt
    22141 caagtctcaa ggggcaaacg atatgcttcg tattcaagga aacaaagaaa aagttagtct
    22201 cactcagaaa ttaactggtt tgaaaccaaa taccaagtat gccgtttatg tcggtgtcga
    22261 taaccgtagt aatgccaagg cgagcatcac tgtaaacact ggtgaaaaag aagtgactac
    22321 ttataccaat aagtctctcg ctctcaacta tgttaaggcc tacgcccaca atacacgtcg
    22381 tgacaatgct acagttgaca atacaagtta cttccaaaac atgtacgcct tctttacaac
    22441 tggatcggac gtatcaaatg ttactcttac tttaagtcgc gaagctggtg atcaagcaac
    22501 ttactttgat gaaattcgta cctttgaaaa caattcaagc atgtacggag aaaaccatga
    22561 tacaggtaaa ggcaccttca aacaagactt tgaaaatgtt gctcagggta tcttcccatt
    22621 cgtagtgggt ggtgtcgaag gtgttgaaga caaccgcact cacttgtctg aaaagcatga
    22681 tccatataca caacgtggtt ggaacggtaa gaaagttgat gatgttatcg atggaaattg
    22741 gtcactcaag accaatggac tggttagccg tcgtaacttg gtttaccaaa ccatcccaca
    22801 aaacttccgc tttgaagctg gtaagaccta ccgtgtaacc tttgaatacg aagcaggttc
    22861 agataatacc tatgcttttg tagtcggtaa gggagaattc cagtcaggtc gtcgtggcac
    22921 tcaagcaagc aacttagaaa tgcatgaatt gccaaatact tggacagatt ccaagaaagc
    22981 caagaaggca accttcctcg tgacaggtgc agaaacagga gatacttggg taggtatcta
    23041 ctcaactgga aatgcaagta atactcgtgg tgattctggt ggaaatgcca acttccgtgg
    23101 ttataacgac ttcatgatgg ataatcttca aatcgaagaa attaccctaa caggtaagat
    23161 gttgacagaa aatgctctga agaactactt gccaacggtt gccatgacta actacaccaa
    23221 agagtctatg gatgctttga aagaggcggt ctttaacctc agtcaggccg atgatgatat
    23281 cagtgtggaa gaagcgcgtg cagagattgc caagattgaa gctttgaaga atgctttggt
    23341 tcagaagaaa acggctttgg tagcagatga ctttgcaagt cttacagctc ctgctcaggc
    23401 tcaagaaggt cttgcaaatg cctttgatgg caatgtgtct agtctatggc atacatcatg
    23461 gggcggagga gatgtaggca agcctgcaac catggtcttg aaagaaccaa ctgaaatcac
    23521 tggacttcgt tatgttccac gtggatcagg ttcaaatggt aacttgcgag atgtgaaact
    23581 tgttgtgaca gatgagtctg gcaaggagca tacctttact gcaactgatt ggccaaataa
    23641 caacaaacca aaagatattg actttggtaa gacaatcaag gctaagaaaa ttgtccttac
    23701 tggtaccaag acatacggag atggtggaga taaataccaa tctgcagcgg aacttatctt
    23761 tactcgtcca caggtagcag aaacacctct tgacttgtca ggctatgaag cagctttggt
    23821 taaggctcag aaattaacag acaaagacaa tcaagaggaa gtagctagcg ttcaggcaag
    23881 catgaaatat gcgacggata accatctctt gacggaaaga atgatggaat actttgcaga
    23941 ttatctcaac caattaaaag attctgctac gaaaccagat gctccaactg tagagaaacc
    24001 tgagtttaaa cttagatctt tagcttccga gcaaggtaag acgccagatt ataagcaaga
    24061 aatagctaga ccagaaacac ctgaacaaat cttgccagca acaggtgaga gtcaatctga
    24121 cacagccctc ttcctagcaa gtgttagcct agccctatct gctctctttg tagtaaaaac
    24181 gaagaaagac tagtatttag taaaacctct taacaagatt acggaagcag tctctatctt
    24241 ttccaatgag gtttatagta cagaaaaagc ctgagaagat atcttctcag gcttttgtta
    24301 agcacataaa tacaatagtg ctatgaaaaa atcacccaga aaaatctgga tgataaatgt
    24361 tatggttgtg ctggttgagg attctgattt tgttgatcag gggttgtatt tgattgttgc
    24421 gtattattgt taggattggt agtcgtacta ttatttgtgc ttggagtggt tgagctagac
    24481 tgtgaagttg aactatctga tgatgagctt gaactttcag ttgatggggg ttgttgtgga
    24541 gcaggtgagc tccacgtaga acgagcacca tttttaaata cgaattctcc atttctgtag
    24601 agcccctctg gtatattcca atcctctgga ttgcttcctt cagacaggta ggtcatcata
    24661 gagcggtaaa ctttggcagc gaccgtaagg ccattgccta caagtggtgt cagacggtta
    24721 gaatagcctg tccatacagc cattgaatat ttacgcgtat agccagcaaa tagttcatca
    24781 ggtgctacaa attgagaggt cttgatgtgg ttttcaattt cctcgtctgt atagttagag
    24841 gttcctgttt taccagcctg agggagccaa gcaagatagg catttcgtcc agttccataa
    24901 ctcaagactg ttttcatcat gtcggtcatc atataggctg tcgtttcctt catggcacga
    24961 gttccgacat tagagaactc tttttcactc ccatcactaa agacgacttt atggatatac
    25021 attggtttat agtaagttcc accatttgca aaggcagcgt aagcagcagc catcttttca
    25081 ctacttgctc catatttttt gtctgattcg gttgtgttac ttgaaatggc atttgagtag
    25141 tgaatacttg ggtagtcgat tccgagacca tttaggaaag tcttggcgcg gttgagtccg
    25201 accttgttta gagtttccac ggctgggacg tttcgcgatt gttgcagggc gtattgcaag
    25261 gtgatgttgc caaagtagcc cctatcccag ttataaacag gggtatttgt cccagggtag
    25321 ttatagggct catcgtgaac gatagtagca gttgaatcgt agacaccgta ctccaaggca
    25381 ggagcatagt ctgtgatcgg tttcatagtt gatccccagt cgcggtttgt ttctactgct
    25441 tggttaattc cgaaggaaac attacttgac tgatggcgtg ctcctagctg ggcaatgact
    25501 ttaccgttag aaacatcaac aatggtagaa gcgacttgca attcatcgtc tggataggca
    25561 acgtattcgt ctgtattgta aatatcccac agatgttttt gagcttcttg gtctacattt
    25621 gtgtagacat ccatcccagt tgtgagcagg ttatagcctg tttcttcttc cacttgattg
    25681 atgacttcct tgaggtaatt atccatgtaa gcagggtaat tacttgctga tttgagactt
    25741 tgtagtccat cagtaattgg tgtattgact gctttctcat actgttcagc agagatgtag
    25801 ccttgatttt tcatttcaga taagaccaag tttcggcggt cttgggctgc ttctggatgt
    25861 gaataggggt catattggtt tggtgcctga ggcattccag ccagcaaggc taactgaggt
    25921 aaacttaaat tattgaggtc tttaccatag tagttttgag ctgctgtctg cattccatag
    25981 ttcccattag acatgtagac cttatttata tagtaggtca agatttcttg cttggttgct
    26041 ttttgttcta actgaatcgc taaccaagct tcctgagcct tacgagaaat agtctggtcg
    26101 gaagtcgaag ttgaaaagta agtcaactta atcaactgtt gggtgagagt tgatccacct
    26161 tggagggaat tgctttgcag attgcgcaag aaagctccca ggatacggat ggtatcaatc
    26221 cccctgtggt cgaagaagcg atggtcttcg atagaaacga ttgccttaac caaatctgtg
    26281 ggaatatcat tagcttgggc attgacgcgg cgttcagaac ccaagtcagc aatgagttga
    26341 tttttattgt cgtagatttt actagaagtt gttgcaacta gtttactctc ggataggcta
    26401 ggagccttgc taacgtagta gaaaaaaact cctccgccta agacaatggc tgcgataacc
    26461 aagcttaaga agctaatgct cagatacttg attaggcgca gaatcgttgg tttgttcatc
    26521 ttgttttacc acctaataaa tgttctttga taacattgag ataaggaatt tgagggaagg
    26581 caccagcctt gatttcatat ccatattctc gaatatattc aagtggcatt gatttttgtc
    26641 ccttatcttg atgatagaag cgaatcaaat cgaatgccgg caataagtag gtttcttgct
    26701 gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg ggcaaggact tgttccatat
    26761 gctgaatctg atgtggatga aaatttttca tcggaatcgc acgtttttgt tttgtttcct
    26821 tgacttcaaa gtcgatgtaa tatccattat aaacgccaga atagtccgtc gttgaagctt
    26881 gtcgaaaata ggcttcaaca atcttggcac gacttcgttg tggatagtcc acttgtacga
    26941 tttgaatagg agttggtttc ttatgtataa cagccaagcc ctgagacaaa tagtagtcgt
    27001 tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt tgcgaaattt ttgggttgag
    27061 aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg atagttgacc ataattctcc
    27121 ttattggtac aataacatca ctttattata ccataatttg cacagaaagg gttaaaaatg
    27181 gctacagctt tggttttagg ctattctact tttgatttgg gtttattttc tgataaggat
    27241 cctcgtctta aattgattaa aaaagcgata cgtaaagatt tagaggctat ggcagcagat
    27301 ggggtgtctt ggcttgtgtt tacaggaagt ttgggttttg aatattgggt tttagaggtt
    27361 gctcaggaga tgaaaaccga atacggtttc cagttggcca ccatttttgc ttttgaaacc
    27421 catggggaaa attggaatga aggtaatcag atgaaactga gtcgctttaa gcaggtagac
    27481 tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc agttaagaga ttaccagcag
    27541 tttttgctgg aaaacacgac tagttcctat cttttttatg atgaagaaaa tgaaacaaaa
    27601 ctagcttatt tttaccaaaa gatgaaaaat caagaggact attttataaa gagattaaca
    27661 tttgatcaat taaatgaact tgctgaaaat ttttccgaaa attgaagctt tgaccttgat
    27721 ttttgtttgc ctttttttat ataataatac tagcaagcga gaatggagag agacatggca
    27781 agtattattt tttcagcgaa agatattttt gaacaagagt ttggacgtga agtccgtggc
    27841 tataataaag tagaagttga cgagttttta gacgatgtca tcaaggacta tgaaacctat
    27901 gctgccttgg tcaagtcact tcgtcaggaa attgcggatt tgaaggaaga attaactcgt
    27961 aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag cggcaattac aagttctatg
    28021 acgaattttg atattttgaa acgcctgaat agattggaaa aagaagtttt tggtaaacaa
    28081 attttagata actcagattt ttaagtagtt atttgagatg tgcaattttt ggataatcgc
    28141 gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc acaggctgtg atgcctgtag
    28201 tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa tcgttacggc agttgaaatg
    28261 gctaagtcct tggataggcc agagtaggct tgaaagtgcc acagtgacgg agtctttctg
    28321 gaaacagaga gagtggaacg cggtaaaccc ctcaagctag caacccaaat tttggtcggg
    28381 gcatggagta tgcggaaacg aacgtagtat tctgactgct atcagctaga gctgttagtg
    28441 gtagacagat gattatcgaa ggaagtggtc ctagtcactt ctggaacaaa acatggctta
    28501 tagaaaattg catataggtt ggggctgaga aattttctca acctcatttt ttaaagtgga
    28561 catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga atttaattta attgcaactg
    28621 tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg agagttgggc tacgattgtc
    28681 aggttgaaaa tggacgtgtt cgttttcaag gagacgtgag agctattatc gaaaccaacc
    28741 tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg aacgttccca gctaagactt
    28801 ttgaagagct atttcaggga gttttcgctt tagattggga aaattattta ccacttggag
    28861 ctcggttacc gatttcaaaa gctaaatgtg ttaagtccaa acttcacaat gagcccagtg
    28921 ttcaggctat ttctaagaaa gctgttgtca agaaattgca gaaacactat gctcgcccag
    28981 aaggggttcc tctgatggag aatggcccag agtttaagat tgaggtctct attctcaaag
    29041 atgtggcaac tgtcatgatt gatacgaccg ggtctagcct ctttaaacgt ggttatcgta
    29101 ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc agccatttta caactttcta
    29161 actggtatcc agacaagcct ttgattgatc cgacctgtgg ttcggggact ttctgtattg
    29221 aggcagttat gattgctaga aagatggcgc caggtcttcg tcgctctttt gcatttgatg
    29281 aatggaactg gatcagcgat cgcttgattc aagaagtgcg cacagaagcg gctaaaaaag
    29341 tagaacgtaa gcttgagttg gatatcatgg gctgtgatat tgatgctcgc atggtggaaa
    29401 ttgctaaggc caatgctcag gcagctggtg ttgcaggaga tattactttt aagcagatgc
    29461 gcgtgcagga tttacgttcc gataaaatca atggagtaat catttccaat ccgccttatg
    29521 gtgaacgttt gtcagatgat gcaggagtga ccaagctcta tgctgagatg gggcaagtat
    29581 ttgcaccgct gaaaacttgg agcaaattta tcctgactag tgatgaagct tttgaaagca
    29641 agtatggtag ccaagcagat aagaagcgta agttatacaa cggaaccttg aaagtggatc
    29701 tatatcaata ttttggtcag cgtgtcaaac ggcaagaggt aaaatagaaa gggatactca
    29761 tgagtaaaaa aagacgaaat cgtcataaaa aagaaggtca agaaccgcaa tttgattttg
    29821 atgaagcaaa agagctaaca gttggtcaag ctattcgtaa aaatgaagaa gtggaagcag
    29881 gagtcttgcc tgaggattcc attttggaca agtatgttaa gcaacacaga gatgaaattg
    29941 aggcggataa gtttgcgact cgtcaataca aaaaagagga gttcgttgaa actcagagtc
    30001 tggatgattt aattcaagag atgcgtgagg ctgtagagaa gtcagaagct tcttcggagg
    30061 aagttccatc ttctgaagac atcttactac ccttgcctct ggacgatgag gagcaaggct
    30121 tggatcctct attgctagat gatgaaaatc caacagaaat gactgaagaa gtggaagagg
    30181 agcaaaacct ttctcgtctg gatcaagagg actcagaaaa gaaaagtaaa aaaggcttta
    30241 ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt cagtgcttat tatgtctatc
    30301 gtcaagtggc tcgttcgacc aaggaaattg aaacttctca atcaactaca gccaatcaat
    30361 cggatgtgga tgattttaat acactttatg acgcctttta cacaaatagc aataaaacgg
    30421 ctttgaaaaa tagccagttt gataaactga gtcaactcaa gactttactt gataagctgg
    30481 aaggtagtcg tgaacatacg cttgccaaat ctaaatatga tagtctagta acgcaaatca
    30541 aggccattca agatgtcaat gcacaatttg aaaaaccagc tattgtggat ggtgtgttgg
    30601 ataccaatgc caaagccaaa tcggatgcta aatttacgga tattaaaact ggaaatacgg
    30661 agcttgataa agtgctagat aaggctatca gtcttggtaa gagccagcaa acaagtactt
    30721 ctagctcaag ttcaagtcaa actagcagct caagttcaag tcaagcaagt tcaaatacga
    30781 ctagtgagcc aaaaccaagt agttcaaatg agactagaag tagtcgcagt gaagtcaata
    30841 tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc cagtcgtgtt gcctataatc
    30901 agtctgctat tgatgatagt aataactctg cctgggattt tgcggatggt gttttggaac
    30961 aaattctagc aacttcacgt tcacgtggct atatcactgg agaccaatat atccttgaac
    31021 gtgtcaatat cgttaacggc aatggttatt acaacctcta taagccagat ggaacctatc
    31081 tctttaccct taactgtaag acaggctact ttgtcggaaa tggcgctggt catgcggatg
    31141 acttggacta ctaagcagtc gttacaaaat tctttctttt caaaagtaaa aatgataaaa
    31201 taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc taactttggt gtcgtaggta
    31261 tggccgtaat gggtcgtaac cttgccctta atattgaatc acgtggttac acagttgcta
    31321 tctacaaccg tagtaaagaa aaaacggaag atgtgattgc ttgccatcct gaaaagaatt
    31381 ttgtaccaag ctatgacgtt gaaagttttg taaactcaat cgaaaaacct cgtcgtatca
    31441 tgctgatggt tcaagctgga cctggtacag atgctactat ccaagccctt cttccacacc
    31501 ttgacaaagg tgatatcttg attgacggag gaaacacttt ctacaaagat accatccgtc
    31561 gtaatgaaga attggcaaac tcaggtatca actttatcgg tactggagtt tctggtggtg
    31621 aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg acaaaaagag gcctacgaat
    31681 tggtttcgga tgttcttgaa gaaatctcag ctaaagcacc agaagatggc aaaccatgtg
    31741 tgacttatat cggtcctgat ggagctggtc actatgtgaa aatggttcac aacggtatcg
    31801 agtacggtga tatgcaattg atcgcagaaa gctatgactt gatgcaacac ttgctaggcc
    31861 tttctgcaga ggatatggct gaaatcttta ctgagtggaa caagggtgaa ttggatagct
    31921 acttgatcga aatcacagct gatatcttga gccgtaaaga cgatgaagac caagatggac
    31981 caatcgtaga ctacatcctt gatgctgcag gtaacaaggg aactggtaaa tggacgagcc
    32041 aatcatctct tgaccttggt gtaccattgt cactgattac tgagtcagtg tttgcacgct
    32101 acatttcaac ttacaaagaa gaacgtgtac atgctagcaa ggtgcttcca aaaccagctg
    32161 ccttcaactt tgaaggagac aaggctgaat tgattgaaaa aatccgtcaa gccctttact
    32221 tctcaaaaat catttcatac gcacaaggat ttgctcaatt gcgtgtagcc tctaaagaaa
    32281 acaactggaa cttgccattt gcagatatcg catctatctg gcgtgatggc tgtatcatcc
    32341 gttctcgttt cttgcaaaag attacagatg cttacaaccg cgatgcagat cttgccaacc
    32401 ttcttttgga cgagtacttc ttggatgtta ctgctaagta tcaacaagca gtgcgtgata
    32461 tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac tttctcagca gctattactt
    32521 actttgatag ctaccgttca gctgaccttc cggctaactt gatccaagca caacgtgact
    32581 actttggtgc tcacacttac caacgtaaag acaaagaagg aaccttccac tactcttggt
    32641 atgacgaaaa ataagtaggt cagccatggg gaaacggatt ttattacttg agaaagaacg
    32701 aaatctagct cattttttaa gtttggaact ccagaaagag cagtatcggg ttgatctggt
    32761 agaggagggg caaaaagccc tttccatggc tcttcagaca gactatgatt tgattttatt
    32821 gaacgttaat ctgggagata tgatggctca ggattttgca gaaaaattga gtcgaactaa
    32881 acctgcctca gtcatcatga ttttagatca ttgggaagac ttgcaagaag agctggaagt
    32941 tgttcagcgt tttgcagttt catacatcta taagccagtc tttatcgaaa atctggtagc
    33001 gcgtatttcg gcgatcttcc gaggtcggga cttcattgat caacactgca gtctgatgaa
    33061 agttccaagg acctaccgca atcttaggat agatgttgaa catcacacgg tttatcgtgg
    33121 tgaagagatg attgctctga cccgccgtga gtatgacctt ttggcgacac ttatgggaag
    33181 caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt tggaagtatg aaagtgcgac
    33241 cgagacaaat atcgtagatg tctatatccg ctatctacgg agcaagcttg atgttaaagg
    33301 acaaaaaagc tacattaaaa ccgtgcgtgg tgttggttac accatgcaag aatagaaaag
    33361 cagttgcagt tgtgtaactg cttttttgag gagtttttat atattgacat gcagtcgtgt
    33421 ctttgctaca atcgttttag gaggatatat aaatgaaact tttgaaaaaa atgatgcaag
    33481 ttctactagc agtctttttc tttggtttgc tagctacaaa tacggtattt gcgaatacca
    33541 caggtggccg atttgttgat aaggataata gaaaatatta tgtaaaagat gatcataaag
    33601 caatctattg gcataaaata gacggtaaaa cttactattt tggtgatatt ggagagatgg
    33661 ttgtcggttg gcaatactta gaaattcctg gaacaggtta tcgtgatgat ttatttgata
    33721 atcgtccagt cttcgaaatt ggccttcagg agaagtggta ctattttgga caagatggtg
    33781 ctttgctaga acaaacagat aaacaagtac tagaggcaaa aacgtctgaa aatacaggaa
    33841 aagtatacgg tgaacaatat cctctatctg ctgaaaagag aacttattat tttgataata
    33901 attatgctgt aaagacaggc tggatttatg aagacggcaa ttggtattat ttaaataagc
    33961 taggaaattt tggtgatgat tcttacaatc cactaccaat tggtgaagtt gctaagggtt
    34021 ggactcaaga ttttcatgtt actattgaca ttgatagaag caaacctgct ccatggtact
    34081 acctccgttc ctcaggagca atggccactg gctggtatca ggaaggtacc acttggtatt
    34141 atttagacca gccaaatggc gatatgaaaa caggttggca aaaccttggg aacaaatggt
    34201 actatctccg ttcctcagga gctatggcaa ctggttggta tcaagatggt tcaacttggt
    34261 actatttaga tccttctaat ggagatatga aaataggttg gacaaaagta aatggaaaat
    34321 ggtattatct caattcaaat ggagcaatgg ttacaggtag tcaaactatc gatggtaaag
    34381 tttataactt cgcttcatct ggtgagtgga tttaatgttg gaggatatat aaaatgaagc
    34441 ttttgaaaaa aactatgcaa gctggactaa cagtaatttt ctttggtttg ctagctacga
    34501 atacagtatt tgcagataac tctgaaggat ggcagtttgt ccaagaaaac ggtagaacct
    34561 attacaaaaa gggggacctc aaagaaacct actggcgagt gattgatggt aagtactatt
    34621 attttgattc tctatctgga gagatggttg tcggctggca atatatcccg tttccatcta
    34681 aaggtagtac aattggtcct tacccaaatg gtatcagatt agaaggtttt ccaaagtcag
    34741 agtggtacta ctttgataaa aatggagtgc tacaagagtt tgttggttgg aaagaattag
    34801 agattaaaac tcaagacagt gttggaagaa agtatgggga aaaacgtgaa aattcagaag
    34861 ataaagaaga gaagcgttat tacacgaact attactttaa tcaaaatcat tctttagaga
    34921 caggttggct ttatgatcag tctaactggt attatctagc taaaacagaa attaatggag
    34981 aaaactatat tggtggtgaa agacgtgcag gttggataaa tgatgcttca gcttggtact
    35041 acctagatcc agcaactggt attatgcaaa caggttggca atatctaggt aataagtggt
    35101 actacctccg ttcctcagga gcaatggcca ctggctggta tcaggaaggt accacttggt
    35161 attatttaga ccacccaaat ggcgatatga aaacaggttg gcaaaacctt gggaacaaat
    35221 ggtactatct ccgttcatca ggagctatgg caactggttg gtatcaagat ggttcaactt
    35281 ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag gtcaatggca
    35341 actggtacta tgcttatagc tcaggtgctt tggcagtgaa tacgaccgta gatggctatt
    35401 ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat tatattagaa
    35461 cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg ggagattaaa
    35521 agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt gactaaccat
    35581 tgacaaaaga taagagcaat caaaataaga tacaaaaata tcaatgctaa ctgcaccgaa
    35641 acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag aatgtctact
    35701 gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatatgggc aaagacagct
    35761 gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact ggtcacgaaa
    35821 attacgatat aggcttgaca aaggatacta gttattagag ccaataggga aatctcacag
    35881 aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt catattgcca
    35941 aggatagctc cacaagacat gatgatggag agcagggcga agagttgccc aatgctcagt
    36001 tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac atccaagatg
    36061 gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaacct caggagcaca
    36121 gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt atgtgacatt
    36181 tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc caaaaaggca
    36241 atgacaaaag tcagagtgtt gataagggaa atagtttgaa tactcataac attgataagg
    36301 aatgcgccag ctagattggc gacaatgcgg acaaccctca tcagagactg cctgaacccc
    36361 atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat catgtaggca
    36421 gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat gactgaaatt
    36481 aatgaaaagg gcgacaagac gagaaatagt gtcaaaatag cgtagagcag gattttgatt
    36541 ttggcaatac agagtgcgtg tttgactcta ttttcttgaa aatctcctag aatcccgaga
    36601 aagagttgcg atagtagggg aactatctct gaaatggaaa tcagtaaaat cgctagcgga
    36661 gcgaaattgt actgagccac ataattgata atggcgaggt agaaaatact gtcgccgaat
    36721 gatgaaaaac agctgtttag cagcaactgt ctatatatgt tgtttgtcca aaataatttc
    36781 atacttttct ccttatgtct gcacatcgaa tgggaattta ttatttaata gacaccaata
    36841 taccccctgc ttcctattcc gaagtcaaac aaatctgctt taccactatc tccttgaaac
    36901 atcagtaaac cgtgatcatc tcgttcagaa catgctaaaa ttacctgttg gattttttca
    36961 tcagtaattt gttttgattg tagacagtgg tttgtagtaa gctagttatt ccgtggcaat
    37021 atcctgtcat catttttaga tgatggttaa aaacaaattc ttgatattta ctaataatat
    37081 ctttgtttcc gtcacaatcg tacatacaaa gatataagat tattccggaa attccttcgc
    37141 accaagaaag ttgtaaattt cctaaatttt cagtattaga agtaactttt tctaataatt
    37201 tttttaattc agcatggaat gtatggagat cattatagaa catagaaggt tctaagactt
    37261 tagaataggc aaataaagca tatgcaattc cacaatatcc atgagcaaag ctatagtcta
    37321 aaatgctttc tttggctgta tctctttgta ggaaataatg ataaatttcc ccatatacta
    37381 ttgtggatga aagttttaag agtattgtca ttggtaaatt gatagtattt tattaatgat
    37441 aataggacac cagattttcc caatgcaaag tctatttcct ctagagtatc ataattctct
    37501 attaatttct tagcggtgac gtttgctaat tgtagatagt attgattttt actgatagaa
    37561 aataaatgta ggagtaacca tagatagcct gcatcaccaa atagcagtga gtattgatat
    37621 tcatatgtat gtgtcgttct aattgtcact gccttcttga tgatagagag tattttagaa
    37681 tccagttctg gggggtacaa tttatttaga ggaaacagta gtccagctat tccgtgttgg
    37741 aatgataaat tacttacgaa atttctaaat tctgttgaag aagtgatcct tccttcagaa
    37801 tttacagttt tatctagtaa aaattgtaga acactattac attctgtttt gtaatcatat
    37861 ttatgttcct ctattttttt aattttgact aaattatttg tttgacttaa atttagtaga
    37921 cattgtaacc aaaatagttg ctcatctgtg agctgacctt gagtatgtga tagttctagt
    37981 aattgaatag gatcctttag gtagattcaa tcaatctata acacaacaac ataataacac
    38041 ttttaggata acttatcaaa tattatagta aaatgaaata ataacaggac aaatcgatca
    38101 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagtttca
    38161 atctactata gtatatattt ttacatcttg aattgtcaaa ttaagtgcat aagtttcccg
    38221 tagcatactt cataaggcgt tttccactta agaaattttc gtggtcgatt atttagaacc
    38281 tgtattcaca aaaaaatgtt aagctagagt tatgatacgc aaagcatatg atactgattt
    38341 aaacgatcaa gaatgggcga agattgaacc ctatttctcc aaacaccgca cctataaatg
    38401 gccgaaacga gtacttgtta atgagacttt gtacgtcact aaaacaggtt gtcaatggcg
    38461 catgctccct cacgactttc ctctttactt aatggtatgg agtttctttc gtcgttctat
    38521 gacgacaggt tggttccagg tcaatggcag atggtactac gcttatagcg ctcaggtgcc
    38581 ttggcagtga atacgaccgt agatggctat tctgtcaact ataatggcga atgggttcaa
    38641 taatgaaaga agcgattgtg aatggaaaca atcgcttttt ttgtgaaaat ataataaaat
    38701 agataggaaa gaattaatac ttgtatgaaa aataagacgt tttttcgtct agtaaaagga
    38761 aaaaatgaca aaaaaagttg gtgtcggtca ggcacatagt aagataattt taatagggga
    38821 acatgcggtc gtttacggtt atcctgccat ttccctgcct cttttggagg tggaggtgac
    38881 ctgtaaggta gttcctgcag agagtccttg gcgcctttat gaggaggata ccttgtccat
    38941 ggcggtttat gcctcactgg agtatttgaa tatcacagaa gcctgcattc gttgtgagat
    39001 tgactcggct atccctgaga aacgggggat gggttcgtca gcggctatca gcatagcggc
    39061 cattcgtgca gtatttgact actatcaggc tgatctgcct catgatgtac tagaaatctt
    39121 ggtcaatcga gctgaaatga ttgcccatat gaatcctagt ggtttggatg ctaagacctg
    39181 tcttagtgac caacctattc gctttatcaa gaacgtagga tttacagaac ttgagatgga
    39241 tttatccgcc tatttggtga ttgccgatac gggtgtttat ggtcatactc gtgaagccat
    39301 ccaagtggtt caaaataagg gcaaggatgc cctaccgttt ttgcatgcct tgggagaatt
    39361 aacccagcaa gcagaagttg cgatttcaca aaaagatgct gaaggactgg gacaaatcct
    39421 cagtcaagcg catttacatt taaaagaaat tggagtcagt agccctgagg cagacttttt
    39481 ggttgaaacg actcttagcc atggtgctct gggtgccaag atgagcggtg gtgggctagg
    39541 aggttgtatc atagccttgg taaccaattt gacacacgca caagaactag cagaaagatt
    39601 agaagagaaa ggagctgttc agacatggat agagagcctg taacagtacg ttcctacgca
    39661 aatattgcta ttatcaaata ttggggaaag aaaaaagaaa aagagatggt gcctgctact
    39721 agcagtattt ctctaacttt ggaaaatatg tatacagaga cgaccttgtc gcctttacca
    39781 gccaatgtaa cagctgacga attttacatc aatggtcagc tacaaaatga ggtcgagcat
    39841 gccaagatga gtaagattat tgaccgttat cgtccagctg gtgagggctt tgtccgtatc
    39901 gatactcaaa acaatatgcc tacggcagcg ggtctgtcct caagttctag tggtttgtcc
    39961 gccctggtca aggcttgtaa tgcttatttc aagcttggat tggatagaag tcagttggca
    40021 caggaagcca aatttgcctc aggttcttct tctcggagtt tttatggacc actaggagcc
    40081 tgggataagg atagtggaga aatttaccct gtagagacag acttgaaact agctatgatt
    40141 atgttggtgc tagaggacaa gaaaaaacca atctctagcc gtgacgggat gaaactttgt
    40201 gtggaaacct cgacgacttt cgacgactgg gttcgtcagt ctgagaagga ctatcaggat
    40261 atgctgattt atctcaagga aaatgatttt gccaagattg gagaattaac ggagaaaaat
    40321 gccctggcta tgcatgctac gacaaagact gctagtccag ccttttctta tctgacggat
    40381 gcctcttatg aggctatgga ctttgttcgc cagcttcgtg agaaaggaga ggcctgctac
    40441 tttaccatgg atgctggtcc caatgttaag gtcttctgtc aggagaaaga cttggagcat
    40501 ttatcagaaa ttttcggtca tcgttatcgc ttgattgtgt caaaaacaaa ggatttgagt
    40561 caagatgatt gctgttaaaa cttgcggaaa actctattgg gcaggtgaat atgctatttt
    40621 agagccaggg cagttagctt tgataaagga tattcccatc tatatgaggg ctgagattgc
    40681 tttttctgac agctaccgta tctattcaga tatgtttgat ttcgcagtgg acttaaggcc
    40741 taatcctgac tatagcttga ttcaagaaac gattgctttg atgggagact tcctcgctgt
    40801 tcgtggtcag aatttaagac ctttttctct agaaatctgt ggcaaaatgg aacgagaagg
    40861 gaaaaagttt ggtctaggtt ctagtggcag cgtcgttgtc ttggttgtca aggctttact
    40921 ggctctgtat gatgtttctg ttgatcagga gctcttgttc aagctgacta gcgctgtctt
    40981 gcttaagcga ggagacaatg gttccatggg cgaccttgcc tgtattgtgg cagaggattt
    41041 ggttctctac cagtcatttg atcgccagaa ggtggctgct tggttagaag aagaaaactt
    41101 ggcgacagtt ctggagcgtg attggggctt ttcaatttca caagtgaaac caactttaga
    41161 atgtgatttc ttagtgggat ggaccaagga agtggctgta tcgagtcaca tggtccagca
    41221 aatcaagcaa aatatcaatc aaaatttttt aagttcctca aaagaaacgg tggtttcttt
    41281 ggtcgaagcc ttggaacagg ggaaagccga aaaagttatc gagcaagtag aagtagccag
    41341 caagctttta gaaggcttga gtacagatat ttacacgcct ttgcttagac agttgaaaga
    41401 agccagtcaa gatttgcagg ccgttgccaa gagtagtggt gctggtggtg gtgactgtgg
    41461 catcgccctg agttttgatg cggaatcaac caaaacctta aaaaatcgtt gggccgatct
    41521 ggggattgag ctcttatatc aagaaaggat aggacatgac gacaaatcgt aaggacgagc
    41581 atatcctcta tgcccttgag cagaaaagtt cctataatag ctttgatgag gtggagctga
    41641 ttcattcttc cttgcctctt tacaatctgg atgaaatcga tctttcgaca gagtttgctg
    41701 gtcgaaagtg ggactttcct ttttatatca atgccatgac tggtggaagt aataagggaa
    41761 gagaaatcaa tcaaaagctg gctcaggtgg cggaatcctg tggtatttta tttgtaacgg
    41821 gttcttatag cgcagccctc aaaaatccaa cggatgattc tttttctgtc aagtctagtc
    41881 atcccaatct cctccttgga accaatattg gattggacaa acctgtcgag ttaggacttc
    41941 agactgtaga agagatgaat cctgttctat tgcaagtgca tgtcaatgtc atgcaggaat
    42001 tactcatgcc cgagggagaa aggaagttta gaagctggca atcgcatcta gcagattata
    42061 gcaagcaaat tcccgttcct attgtcctca aggaagtggg ctttggaatg gatgccaaga
    42121 caatcgaaag agcctatgaa ttcggtgttc gtacagtgga cctatcgggt cgtggtggca
    42181 ccagctttgc ctatatcgaa aaccgtcgta gtggccagcg tgattacctc aatcaatggg
    42241 gtcagtctac catgcaggcc cttctcaatg cccaagaatg gaaagataag gtcgaactct
    42301 tggttagtgg aggggttcgg aatccgctgg atatgattaa gtgcttggtt tttggtgcta
    42361 aggctgtggg attgtcacga accgttctgg aattggttga aacctacaca gttgaagaag
    42421 tgattggcat tgtccaaggc tggaaagcag atctacgctt gattatgtgt tcccttaact
    42481 gtgccaccat agcagatcta caaaaagtag actatcttct ttatggaaaa ttaaaagaag
    42541 caaaggatca gatgaaaaag gcgtaaccag cgcctttttt tccatcctca gactgaggtg
    42601 acttttttga attgtgataa aatagaaggg agaggatgaa cctatgagaa aatttaaaat
    42661 ctttttattt atcgaagcct gtcttctgac aggagctctg attttgatgg tatcagagca
    42721 tttttcgcgt tttctgctga tactattcct ctttttgctt ttgattcgct actacactgg
    42781 taaagaggga aataatcttc ttttagtagc ggcaaccatt ctcttctttt tcatcgttat
    42841 gctcaatcct tttgtgattc tagctatttt tgttgcggtt atctatagcc tctttcttct
    42901 ttacccgatg atgaaccagg aaaaagagca gaccaatttg gtttttgaag aggtcgtgac
    42961 ggttaagaag gagaaaaatc gttggtttgg aaatcttcat catttttcaa gctaccagac
    43021 ttgccaattc gatgatatca atctctttcg cttcatgggt aaggacacta ttcatctgga
    43081 gagggtcatc ttaaccaatc atgacaatgt cattatcctc agaaagatgg taggaacgac
    43141 caaaatcatc gtacctgtag atgtggaagt cagtctcagc gttaactgtc tctatgggga
    43201 tttgactttt ttcaaccagc ccaagcgagc cctccgcaat gaacactatc atcaagaaac
    43261 aaaagactat ctcaagagta acaagagtgt caagattttc ttgaccacta tgattggtga
    43321 tgtggaggtg gttagaggat gaaaaaacaa gcctatgtca ttattgctct cacctccttc
    43381 ctatttgtct tttttttctc ccacagcttg ctggaaatac ttgattttga ctggtctatc
    43441 tttttgcacg atgtcgaaaa aacagaaaaa tttgtctttt tattgttggt tttcagcatg
    43501 tccatgacct gtctcttagc cctgttttgg cgagggatcg aagagctttc tctaagaaaa
    43561 atgcaggcta atctcaagcg tttattggca gggcaagaag tagttcaggt tgtagatcaa
    43621 gatttggatg ccagtttcaa gtccttatca ggtaaactta accttttgac agaggctctt
    43681 caaaaagctg aaaatcatag ccttgctcag gaagaggaaa tcatcgagaa ggaacggaag
    43741 cgaattgctc gggatttgca cgatacagtc agtcaggagt tgtttgcggc ccacatgatt
    43801 ttatcgggta tcagtcagca ggctttgaaa ttggatagag aaaagatgca gacccagttg
    43861 cagagtgtca cagctatttt agaaacagcc cagaaggatt tgcgggtttt gctcttgcat
    43921 ttgcgaccag ttgaactgga gcagaagagc ttgatagaag ggattcaaat tctcttaaaa
    43981 gagcttgagg acaagagtga tcttagggtt agtctcaagc agaatatgac gaaattgcct
    44041 aagaaaatcg aggagcatat cttccgtatc ctgcaagagt tgattagcaa taccctccgc
    44101 catgcccagg catcttgcct agatgtctac ctctatcaga cagatgttga attgcaactg
    44161 aaggtggtgg acaatgggat tggtttccag ttagggagct tagacgactt gagttatgga
    44221 ctgcgaaata tcaaggagcg ggttgaagat atggcaggga cggttcagtt attaacagct
    44281 cccaagcaag ggctggcagt tgatatccgt attcccctgt tagataagga atgataaagg
    44341 agtaaagatg aaaattttac tagtagatga ccatgaaatg gtccgtttgg gtttgaaaag
    44401 ctactttgac ctccaagacg atgtagaagt tgtgggtgag gcgtccaacg ggtctcaagg
    44461 gattgacttg gccttggaac tgcgtccaga tgtcattgtc atggatattg tcatgcctga
    44521 gatgaatggg attgacgcga ccttagcaat ccttaaagaa tggcctgaag ccaagatttt
    44581 gattgtgacc tcttatttgg acaatgaaaa aatcatgcca gtcttagatg ctggtgccaa
    44641 aggctatatg ctcaagactt ctagtgcaga tgaattgctt catgccgtca gtaaggtagc
    44701 tgctggcgag ctggccattg agcaagaggt tagcaagaag gttgaatacc accgcaatca
    44761 tatggaactt catgaagaat tgactgcgcg tgagcgagat gttctccaac tcatcgccaa
    44821 gggctacgaa aatcagcgca tcgcagatga cctctttatc tctctcaaga cggtcaagac
    44881 ccacgtgtcc aatattcttg ccaaacttga agtcagcgat cgtacccagg cggctgtcta
    44941 tgcctttcag caccatttgg tggggcaaga ggagttttag atgagtttag cagatttact
    45001 tgaggagcta gaagcagcaa aagactctaa aaaagcaagg tccatggaag cctatatgcg
    45061 ccatcaattt tcttttctag gtattgcggt gcctgaaaga aataaactct ataaaaatat
    45121 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    45181 aaggagccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    45241 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    45301 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacaccc tgaactagaa
    45361 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    45421 caaaacagtg ttttgagcaa tctgcggcta acttcctagt ttgctctttg attttcattg
    45481 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    45541 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    45601 aaccaaacag aattttttat caataaagcc attggctgga ttctgcgaaa ctactccaaa
    45661 acgaatccaa cttgggtaac atgctttatt gatgaaaaca aggaaagaat ggctgaactt
    45721 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    45781 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    45841 ctatagtaga ttaagaaatt tagaatagta ggctataatt acattaggag gctacaataa
    45901 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    45961 gccagttatc gacagtatct gctttgagtg ttatttctag tacgggtgaa gaatatgagg
    46021 taagtgagac actagaaaaa ggtccaggat ctaatgattc ttcattatct gagatttcac
    46081 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    46141 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    46201 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    46261 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    46321 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    46381 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    46441 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    46501 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    46561 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    46621 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    46681 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    46741 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    46801 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    46861 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    46921 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    46981 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    47041 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaagtcg cactagccac
    47101 atttttcttc ggtttgctag ggaccagtac agtatttgca gatgattctg aaggatggca
    47161 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    47221 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    47281 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    47341 gatttctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    47401 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    47461 atatgatagc ccagcagaga aatgagtcta ttattttgaa gatcagcgta gttatcatac
    47521 tttaaaaact ggttggattt acgaagaggg tcattggtat tatttacaga aggatggtgg
    47581 ctttgattcg cgcatcaaca gattggcggt tggagagcta gcacgtggtt gggttaagga
    47641 ttcccctctt acctatgatg aagagaagct aaaagcagct ccatggtact atctagatcc
    47701 aacaactggc attatgcaaa ctggttggca atttctaggt aatagatggt actacctcca
    47761 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    47821 tgctgaaaat ggtgatatga gaactggctg gcaatacctt ggtaacaagt ggtactatct
    47881 ccgttcatca ggagctatgg caactggttg gtatcaggaa ggttcgactt ggtactatct
    47941 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    48001 tgcctatgat tcaggtgctt tagctgttaa taccacagta ggtggttact acttaaacta
    48061 taatggtgaa tgggttaagt aatgaaggct aattgtaaac tgtgatggat acttaacttt
    48121 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    48181 tactgccccc caaaagttag acaaataatt tatccaaagg atttagttct gtactgcaca
    48241 ggactaagtc cttttagttt taccttaatt ctcttgttgt tgtaataatc aatatagtct
    48301 ataatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    48361 tccgatttca gaatcccaaa gaaggactcc accatagtgc ttctctgtga atgcctgttc
    48421 caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg cgataatttc
    48481 actgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
    48541 aaattctgtc acatctgtgt agcacttttc cattgtttta gagccttcaa attggccttg
    48601 aatgagattc tctgccttct taccaacgtc tcctttattt tcgtttctgt cgcattttag
    48661 cttgtaaatt gagtactttc atcaagcctt gaactctttt atgatttacc agataaccac
    48721 gatttcttag ttctaaatga acccggcgat aagtataatt tcccttgtgt tcgataaaaa
    48781 tggattgaat ttcagcttta agctcttggt ccttatctgg ttt
//
LOCUS       DAVKUR010000009        47999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKUR010000009 DAVKUR010000000
VERSION     DAVKUR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.009"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(62..274)
                     /locus_tag="VW749_000599"
     CDS             complement(62..274)
                     /locus_tag="VW749_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174684.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            complement(617..913)
                     /locus_tag="VW749_000600"
     CDS             complement(617..913)
                     /locus_tag="VW749_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174685.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(897..3056)
                     /gene="pfbA"
                     /locus_tag="VW749_000601"
     CDS             complement(897..3056)
                     /gene="pfbA"
                     /locus_tag="VW749_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0174686.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKINNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4186..5412)
                     /locus_tag="VW749_000602"
     CDS             complement(4186..5412)
                     /locus_tag="VW749_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0174687.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFKNEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5455..6147)
                     /locus_tag="VW749_000603"
     CDS             complement(5455..6147)
                     /locus_tag="VW749_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0174688.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(6320..8071)
                     /locus_tag="VW749_000604"
     CDS             complement(6320..8071)
                     /locus_tag="VW749_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174689.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(8061..9806)
                     /locus_tag="VW749_000605"
     CDS             complement(8061..9806)
                     /locus_tag="VW749_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174690.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9934..10464)
                     /locus_tag="VW749_000606"
     CDS             complement(9934..10464)
                     /locus_tag="VW749_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0174691.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(10461..10917)
                     /locus_tag="VW749_000607"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VW749_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VW749_000608"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VW749_000608"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0174692.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..11988
                     /locus_tag="VW749_000609"
     CDS             11890..11988
                     /locus_tag="VW749_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0174693.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            12033..12272
                     /locus_tag="VW749_000610"
     CDS             12033..12272
                     /locus_tag="VW749_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0174694.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12655..12750
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13150..13731
                     /locus_tag="VW749_000611"
     CDS             13150..13731
                     /locus_tag="VW749_000611"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0174695.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13731..14993
                     /locus_tag="VW749_000612"
     CDS             13731..14993
                     /locus_tag="VW749_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0174696.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15043..15504)
                     /locus_tag="VW749_000613"
     CDS             complement(15043..15504)
                     /locus_tag="VW749_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0174697.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(15501..16265)
                     /locus_tag="VW749_000614"
     CDS             complement(15501..16265)
                     /locus_tag="VW749_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0174698.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYYPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(16446..16850)
                     /locus_tag="VW749_000615"
     CDS             complement(16446..16850)
                     /locus_tag="VW749_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0174699.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVIGQRSEERRVRI"
     gene            complement(16920..18401)
                     /locus_tag="VW749_000616"
     CDS             complement(16920..18401)
                     /locus_tag="VW749_000616"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0174700.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(18420..19598)
                     /locus_tag="VW749_000617"
     CDS             complement(18420..19598)
                     /locus_tag="VW749_000617"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0174701.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKETVGKHYEEVVGYAPSFYIAEVAGGTHVLD
                     "
     gene            19763..20770
                     /gene="galR"
                     /locus_tag="VW749_000618"
     CDS             19763..20770
                     /gene="galR"
                     /locus_tag="VW749_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0174702.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20816..21853)
                     /locus_tag="VW749_000619"
     CDS             complement(20816..21853)
                     /locus_tag="VW749_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0174703.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21854..22207)
                     /locus_tag="VW749_000620"
     CDS             complement(21854..22207)
                     /locus_tag="VW749_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0174704.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(22451..23341)
                     /locus_tag="VW749_000621"
     CDS             complement(22451..23341)
                     /locus_tag="VW749_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0174705.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            23474..24010
                     /locus_tag="VW749_000622"
     CDS             23474..24010
                     /locus_tag="VW749_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0174706.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FIGQEVVQFYLDLLIPKN"
     gene            complement(24176..24982)
                     /locus_tag="VW749_000623"
     CDS             complement(24176..24982)
                     /locus_tag="VW749_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0174707.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(25327..26847)
                     /locus_tag="VW749_000624"
     CDS             complement(25327..26847)
                     /locus_tag="VW749_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0174708.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDSIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26840..27568)
                     /locus_tag="VW749_000625"
     CDS             complement(26840..27568)
                     /locus_tag="VW749_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174709.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(27582..28346)
                     /locus_tag="VW749_000626"
     CDS             complement(27582..28346)
                     /locus_tag="VW749_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0174710.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGATYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(28350..28793)
                     /locus_tag="VW749_000627"
     CDS             complement(28350..28793)
                     /locus_tag="VW749_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0174711.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(29475..29771)
                     /locus_tag="VW749_000628"
     CDS             complement(29475..29771)
                     /locus_tag="VW749_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0174712.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29793..30857)
                     /gene="pepA"
                     /locus_tag="VW749_000629"
     CDS             complement(29793..30857)
                     /gene="pepA"
                     /locus_tag="VW749_000629"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0174713.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALLGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            31258..31959
                     /gene="galE"
                     /locus_tag="VW749_000630"
     CDS             31258..31959
                     /gene="galE"
                     /locus_tag="VW749_000630"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0174714.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            32382..33341
                     /locus_tag="VW749_000631"
     CDS             32382..33341
                     /locus_tag="VW749_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174715.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            33331..34287
                     /locus_tag="VW749_000632"
     CDS             33331..34287
                     /locus_tag="VW749_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0174716.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            34284..35036
                     /locus_tag="VW749_000633"
     CDS             34284..35036
                     /locus_tag="VW749_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0174717.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            35132..36097
                     /locus_tag="VW749_000634"
     CDS             35132..36097
                     /locus_tag="VW749_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0174718.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(36322..36564)
                     /gene="yidD"
                     /locus_tag="VW749_000635"
     CDS             complement(36322..36564)
                     /gene="yidD"
                     /locus_tag="VW749_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0174719.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(36564..37286)
                     /locus_tag="VW749_000636"
     CDS             complement(36564..37286)
                     /locus_tag="VW749_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0174720.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(37273..37842)
                     /locus_tag="VW749_000637"
     CDS             complement(37273..37842)
                     /locus_tag="VW749_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0174721.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37861..38589)
                     /locus_tag="VW749_000638"
     CDS             complement(37861..38589)
                     /locus_tag="VW749_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0174722.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(38589..39329)
                     /gene="xerD"
                     /locus_tag="VW749_000639"
     CDS             complement(38589..39329)
                     /gene="xerD"
                     /locus_tag="VW749_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0174723.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(39320..39781)
                     /locus_tag="VW749_000640"
     CDS             complement(39320..39781)
                     /locus_tag="VW749_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0174724.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39778..40299)
                     /locus_tag="VW749_000641"
     CDS             complement(39778..40299)
                     /locus_tag="VW749_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0174725.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(40275..41246)
                     /locus_tag="VW749_000642"
     CDS             complement(40275..41246)
                     /locus_tag="VW749_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0174726.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(41243..42037)
                     /gene="racE"
                     /locus_tag="VW749_000643"
     CDS             complement(41243..42037)
                     /gene="racE"
                     /locus_tag="VW749_000643"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0174727.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(42244..42492)
                     /locus_tag="VW749_000644"
     CDS             complement(42244..42492)
                     /locus_tag="VW749_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0174728.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42748..44373)
                     /gene="treC"
                     /locus_tag="VW749_000645"
     CDS             complement(42748..44373)
                     /gene="treC"
                     /locus_tag="VW749_000645"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0174729.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(44551..46518)
                     /gene="treP"
                     /locus_tag="VW749_000646"
     CDS             complement(44551..46518)
                     /gene="treP"
                     /locus_tag="VW749_000646"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0174730.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46703..47413
                     /gene="treR"
                     /locus_tag="VW749_000647"
     CDS             46703..47413
                     /gene="treR"
                     /locus_tag="VW749_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0174731.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            47568..>47999
                     /locus_tag="VW749_000648"
     CDS             47568..>47999
                     /locus_tag="VW749_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174732.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYYFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKIMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFE"
BASE COUNT        14100 a        10868 c         8926 g        14105 t
ORIGIN      
        1 acatttaggt acctcttctt aacaaagttc aatagtaaca attaatattt taaacaatat
       61 atcaaacatc aatgactaga atacttgcat catccttctt tccatagatt ggatcaatag
      121 cagaagaatt aaatctcatc ttaattaact cttcaaaagt tttattttga ttattttgat
      181 agaattcata aaagccatcg ctcattaaaa caatttgttc actagtaaca tctatttgat
      241 taataatagc atggtctaaa aatctctcat ccaacgaacc tatccagtac ccactcggtt
      301 gattagataa ttttctgatt ttttgtaaaa taattttttt atttaaaaca ctatttgtac
      361 caattgaatc ttttatctca tttttccctt tttcaaataa gttatctact ctatgatcag
      421 ttatttccat ttcgtttact aacatgacgc agtcacctag catcatatac tccaactttt
      481 tttctgaaag tttagcaaat ataaaagcaa atattggtaa gcgataatat agtatattga
      541 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
      601 ttgatttgtc ctattattat ttcattttac tatactctgt taattcatat gagtttaaac
      661 cgatttcatc tttaacctcg agtaaagcag tttcaaatat ttgtttaaga gtttttgatt
      721 ctttacaatt aaccgacaaa ctttctgata aaatatgtac aacttctgag actgaataac
      781 ctatctcctc tttagaatta tataaatctg tagctccacc aataatccaa aaatactgat
      841 tttgtgaacc tacaatatcc tcattttcta cggaacttcc ttgtatcgaa caaattttat
      901 ttatctttac cataatactt caaccctttt agtgtcaaaa gtaaaccaat tcctgtcact
      961 gttaagaata gttccataat cttgttcgaa ccagtctttg gtaatttttg ttttacatct
     1021 actatttctt tagatttatt aatatgattt tcagtttctc tgccatctcc aactatttta
     1081 tagtttactt cttctgtctt attatcttgt ttattgttga tcttgtcatt catttgtcta
     1141 ttatctttac ttgagttaaa ctctccgttc ttctggttac tatcaattac attatttgaa
     1201 ttagattgtt tttcctcttt gtttttttct ttttcgtttt tatcacttaa attatttgtt
     1261 acaattttgt aaagcccatt ctccgttaca atattgaaat taccatcgct atcacgtata
     1321 acaggttctt tcccatttgc attagatttg atgaatgata tatacttacc ggataaatta
     1381 taaaattggt tatttaaaac ggttatttta ccctttgaat cctcaataac aattccttct
     1441 ttaccaccga atatactatt ctctgagact actaaattat cactaactcg taataattca
     1501 atatttggtt gttctgtttc cttagaatta ttattaacta cattttttgt tacagtaata
     1561 tctgatactt ttcctaaata ttctgcacta tcttttgcaa ctcgtatcgc ttttgtttta
     1621 ggatcggcaa tattaaatat attttcggcg ataaccacct gtttatttaa atctaatagg
     1681 tctttagtgt ttttatagct ataagcattt actaaagctg ctccgctttc tcgataatgt
     1741 acactctctc ctttaacttt cttatcaaag cgatttcctt tgattaatac atcagtgaat
     1801 cctgtaaaac gtacacctga atacatcatg ttatcaaaat gattatttaa aattttaata
     1861 ttagaggggt tctgtgtcga caatgtttga tagtgtgtgc caattgctgt tactaattcc
     1921 ccagatttat cacttttgcc aaaataggaa ttttgaatag tcacattttc agattttttc
     1981 ccatcatcat tcaaggcata aggaaaacct tttctagtta atggttcaat ctgaatgctc
     2041 tccttactta tgatttgccc atccttcatc gttttgggta aggcttgccc aagaaaacga
     2101 gaattatcaa ctaatacatt tttcgaacct gcaatttgaa tagcatgccc ttgataacta
     2161 tccttgaatg ttacattttt tatagttacg ttatttgaat tcccaatagc aaatgcacct
     2221 gaagaattta taagtggtag attttttgct ttagttcctt cttcattcaa agcaccgttc
     2281 atatcaatcg taccaccaga ataactaata tcttctgttg ggccccattc tacttgcgca
     2341 ccatcatccg taaataaacc tgtcataaaa acaatggaag ggtgattctt aatatttata
     2401 ccatttagaa ttgtagcttt ctcattcaat tctaagtgtg tatgactttt taaaaaaaca
     2461 atttctttta ctaaataagt tccttcagga aaatatacat ttcctccacc tagcccttga
     2521 gctgcagcat ctattgcatc ttgaattgct tgtcgatcat catgaatccc atcacctacc
     2581 gcaccataat cttttacact taaagcagta tcttcaaatt cttttttgat aattctgtca
     2641 cttataacat cttccttata actcttattt tcattagtag atgttactgt agattcaact
     2701 gttctgttgt ctaattgtga attggaacga atagtaccat tagagctgat actattaaca
     2761 cttaacgaat tatctaaacc attagtggtt gaattagagg caatcatttc agcagaacga
     2821 ttctgattaa cagttggtga attatctaaa tcattagtaa ttgcattaga agactctttt
     2881 gtagccatcg gtgaagaact agtaacaact tcatccgata aaataccttg gcttcccaaa
     2941 attgaaattg ccaatagtac cgagcaagtc cctaccttta atttacgaat actgaatacc
     3001 tcattaggaa caaaatattt catcagaacc tccaattttt ttactatttt taacaattga
     3061 ttattacttt tcttaaaata gatagaatga caccgctgtc attatcttta tcatatattt
     3121 tccaaattga attgtcaagg aataacacaa gaaaatatta aaatttatac tcttcggaaa
     3181 tctcttcaaa ctaggtcagt gccgccttgc cctaagtcta ggttactgac ttggtcagtt
     3241 ctatagtaga cggaaactat aatagtacac ctctacttct aaaacattgt tagaaatcga
     3301 tttgactgtc ccgatcgatt tgtcctattc ttatttcatt ttactatatc tacaacctca
     3361 aagcagggtt ttgagctatc tatggccaac ttcctagttt gctctttagc cttccattca
     3421 aaagtgatgc tatctttctt agcttgaata taaaatatcc catttactat atttaaattt
     3481 gttgatatgt tgtaaattat aaatgaaaga acaaatacct tgtcatacaa gcattcgcca
     3541 gggatattta catgaatatc gctcatatgg cggattgaaa ctaaaacact acaatatatt
     3601 tcttaaatag accttctata aaagctagat ttaacctcga taaaaataga tgcagtgctt
     3661 ctaaaatact ggaatagggc atataggtaa tcgtagacaa gtgttttata gattgtctcg
     3721 cgggagatct aatgatgtat agcaagcatc actaaacata tagaatattt gtattattat
     3781 aagatcaata tgctataaat tctatcatgc aaaagaatga ctagaacatg aaagacaggc
     3841 acaaaacttt gaacaatatt ctgaaaacaa aaaaagacgc gagtttccac aatctcactc
     3901 atggaaactc acgtctttca aaaaataggg tgaattgaaa actagaacaa gacactagat
     3961 tttctaaatg atgtctagta aggattctaa atgctacacc aaattgctca catcttattt
     4021 caaaccacgg gactctcaca agaaaggaaa atcctataaa aattctctct ctgaggagaa
     4081 agaggcctca actacaggtg taaactatta tcaattgaaa acaacagttt ttacactcaa
     4141 ttagactttt tagggacagg atcactttcg cttgactgta gtttgtcatt tttttgataa
     4201 agttagcact ttttcagaaa ctgttttgaa agtctcaatg atatagtcta cttcttcatc
     4261 gcttaattta gtatgaagag ggagggtaat ttcattctta aagaaggcat aggccttagg
     4321 atagttcgtc atatcaaatc caagattctt ataggctgtc aagagaggaa gcggtttgta
     4381 gtgaacatta cttgcaattc ctgctttagc caattcttgg atgatgaggt tgcgttcttc
     4441 taggcttgct ccttctacac gggtgatgta gaggtggcgt gaagattcga cagtttcagt
     4501 cttgtgtgcc aaaggatgga tgcgagaacc tgcaaaacca ctatcatagc ggtccacaat
     4561 gtccttacgg cgttgcaaca aacttggata gcggtccaat tgtaccaaac caagtgaagc
     4621 catgatatcg gtcatgttgc acttataggc tggtgtaacg atatcgtatt cccatgaccc
     4681 cagttgcatc ttggcaagag catccttagt ttgcccgtga agggaaagga tttggaattc
     4741 cttgtacatc tcttcgtcat caatcactgg attggctttc caagtcgcac ttccaccttc
     4801 tgccgttgta aagttcttaa cggcatggaa tgagaaggaa gtaaagtcag cgatagaacc
     4861 agaaggttgt cctttataag tagatcccaa agcgtgggca ctatcagaga caatgacaat
     4921 acggttaaag gccttttgcc acttgcttga agcagtaaag aagtcacgtt ttttctccac
     4981 gacttggaac aaacggtcat aatcgcaaac aatccctgcg agctctactg ggataatcac
     5041 cttagttttc tcagtgatag cttgctcaag caggtcatag tccatctcaa acgtatctgc
     5101 ttggatatcc accatgacag gggttgctcc cacgtgcgta atgacactac atgaagctgt
     5161 ataggtcatg gctggaacga tgacttcatc accaggtccc acttccaaaa cgcgtaaaat
     5221 caactccaga gcggctgtcg cagagttgag acaaacagtc ttaggtgtct gtgtgtaaag
     5281 agacaagcgg cgctccagtt cttttgtttt aggacctgtt gtgatccaac cagaacgcag
     5341 ggtatccgct acttcagcaa tttctgcttc tgtgatatca ggcggtgaaa atggaatatt
     5401 gtaatttggc attgatttgc tccttttatc tgtactcatt ttcttatgac tactttattt
     5461 tagtacctca aacacggttt gaaacatgat tttgatgtcc ccaaagaaac taaactctcg
     5521 gagataggcg aggttatagc gcatcttttc aggaagaaca tgctccacat aggcctgatc
     5581 aactgacaga cctttctccg tcatttgact gatgatggtg tcctcatcct tgtagttgat
     5641 gctggctgga gaggtaattc ctgcttgcaa gagcaaggtt gccatcattt cagggctata
     5701 ctgctctgta taacgtggca cttcaggtcg tgtaccgaca aaggacatct cacctttaag
     5761 gacattgacc aactgaggca gttcgtccaa acggacacgt cggatgaaat ttccaacctt
     5821 ggtaatacgg ctatcgttag cagaagtcac cagacttcct tttttatccg catccgtcac
     5881 catggtacgg aacttccaaa tcttgaaccg acggttgtac tgggtcacac gctcttgctt
     5941 gtaaatcact ggccccttgc tatccaactt gatccaaatg ctcaagatga gaaagatggg
     6001 agaggttaga accagtaaga ccaaggccaa aaaccagtcc aagcaacgct tgaaaatcag
     6061 cgaacccttc cttttagaga caagatggta gtaagactca acctcgcttg atttcatttc
     6121 cacaggcaag tcttcccatt tcagcatact gttctccttt gtttttatta tactatttgt
     6181 caacattttt cattatacca caaaatggaa aaggcggtga aagaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat cggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagtcaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcga
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgct gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctga tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaaacgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctatcagggc aaagacacga cctgcagaaa
     7141 ccatagccgt ttgcagagtt gaaaagtttt gcgtcacctc aatcaagggg tcaaaaaggc
     7201 ggttgatgta ctggataaag gcatacatgg tcccgaccgt tatcccgata gaaaaaccac
     7261 ggtagccaaa gtaggccatc aagactgcat agcctagaag tttcagcaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc gtagaccaag tgttcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaagcctga ataatcctga
     7441 ttccctcgat attctctgcc agcttactat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctgg ataaaatccc cgaaaacata tcactgatag
     7681 tctcggtgtc atttgtcaaa cgagagacga tagagcctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccta catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cgtgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag tgataatggt tgtcttgtcc tttcgcgtct ccttgaggtt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tctaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcgaccgct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt tgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaaggt ctgtcagacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat tcccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacacg
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctgatgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gacccgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggc gtttttctaa cttgaaaaac
     9781 caccaaagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt ctttttcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttactgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacatctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg ataagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttct gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ccatttgaga gtcaagacca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatagact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcagagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat tcggttccct ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatata
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacaca tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cgcctacgat
    11341 cagttttcca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt taaatatgct gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aatactaacg tccagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt ctcttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 agttagaaaa aggcatattg tcaggtgtct aaaaacttga tagtatgcct tttatgatgg
    12361 aaaaatcttc taatactctt cgaaaatctc ttcaagccac gtcaacgtcg ccttaccgta
    12421 ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt tttgaggttg
    12481 tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag cttacaatga
    12541 agtttttgtt caccctctct tctttttgtt cgctttttaa accaaaacac taacaaaata
    12601 gttgatttct aaagttattt agtgtaaaat aaaaacattg gctcaagcct atttaaaatt
    12661 gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa
    12721 cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgt ctatttaggg
    12781 gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc cttaattagt
    12841 gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa tttcatccct
    12901 aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt ccccgaacta
    12961 ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg ataccactac
    13021 aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa tatatagtat
    13081 tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt ttagacttta
    13141 ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat cttgggtgat
    13201 aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt gatgcgagag
    13261 attggtaagg tttttgcgga aaaatttgct gctactggca ttaccaaggt cgtaaccatt
    13321 gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt tcccatgatt
    13381 ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc tcaagtctac
    13441 tcctttacca agcaggtgac cagcactgtt tctatcgctg gaaaattcct ctcaccagag
    13501 gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa aggcttgatt
    13561 caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat tgagaaatcc
    13621 ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgc
    13681 ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta atgcaaactc
    13741 aagaaaaaca ctcgcaagca gccgttctgg gcttgcagca cttactagcc atgtactcag
    13801 gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct gagcagttga
    13861 cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc caactccaac
    13921 tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc cagtcggtcg
    13981 ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt gcccttatcg
    14041 catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc aatctcttcc
    14101 catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc cctgtcgcta
    14161 ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg cttgcagcta
    14221 ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc aagtctatct
    14281 ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc ttggtggact
    14341 tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac tttgggatgc
    14401 caacctttga aatctcatct attgtcatga tgtgtatcat cgcaacggtg tctatggttg
    14461 agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc gacagcacgc
    14521 gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga atctttaaca
    14581 ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa
    14641 aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg cttcctaagt
    14701 ttggcgccct tgcccaaatc attccaagct ccgtcctcgg tggtgccatg ctggtaatgt
    14761 ttggttttgt atcaattcaa gggatgcaaa tcctcgcccg tgttgacttt gctaacaatg
    14821 aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta
    14881 atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga atcgtcgtag
    14941 ccagcctact cgctattgtc ctcaatgccg tattaaatca taaaaagaaa taagaaaaag
    15001 aggtgcgagc ctcttttttg ttgacaaaat aaaaacatct acctattcat atatgctagt
    15061 gtcatagtcc tgaaaatcat ctgcatcaag aacaatttca caactcttat acttttctct
    15121 tacaagtcgt tcggcttcat ctggattttc agcctctata cttactaaac gtgataaagt
    15181 ttctgtaatt tctactgtat actttttcag ttttagattg ctttccaata attcacctat
    15241 taacaataat ctatgatagg agctatgtag ccactctggc aatttatctc ctacttccca
    15301 cccatatttt tccttcatca aagctagttg tttttcgtca ccaaatttca tattttcaga
    15361 taaccatctc acacaatcgg gatctgataa ggtacagacg attaaactta ggttatcgta
    15421 acggctttca gtttcataat caggccagat gacttttaag aaatcataca cctcttctga
    15481 tgcaacaagt tgtttcgttt tcataatttc cgatactttc ctctaccttt aaattctatt
    15541 atttctttgt ctcttaatat ttgaagctgt tgcctaatct tttctttgat atgattgttc
    15601 ttaacaaaga tattttttag gtcactttca aaacgataca tatcttcaag ggtaaattct
    15661 gaaccctcta tcttatctat acaatttaga atttctattg tccaacctct tgatgacaga
    15721 gagctcttcc ttaaaaataa accttgctta aattcttttg taactttttc tggatctcta
    15781 acttgtccat cttgcacaag aaatatcctt cctttagaag gtacttgtga taaatcaatg
    15841 ttacaaccaa tccaacctgc tcgtctagca gttggtgcaa gtggttttct ttgaataatc
    15901 gatttcggtg taacaaattg cttcggaagg acaagaaagt tatttacctc aaaatttttt
    15961 gtgtaagtta aaaaaaagaa attaggatta ttatctgcct gcacacgctt catcatcgtt
    16021 gcataagcac catcattgat tgttgatgaa aaatttcctt ttttgctctt tagttcaaac
    16081 tcctcactac aatgattaca gtaaaaatct gctacaggcc gattattttc aaaatgattt
    16141 aagggattgt tcccacaatt agggtaataa gactgacgat aaacccaatc ctccgttaag
    16201 atacgtgcct tttggctatt acttttatag gtttctacta attctaaatt aaagtgtaat
    16261 tccatttaaa aattcctcac taatatgaga actcactcga tataagcaat taaaatctac
    16321 tataactagt ataccacata tatgtaccta ttacatttgt atttcatcac tctcttttat
    16381 atttccttct aacatatctc ataaattaaa aatgagtgag ataaatttat cccactcacc
    16441 tttctttata tccttacccg tctttcctca gacctttggc ctatgacaaa catggtaaag
    16501 gttgctttgc agacatttct gccctcttga ttggtgatat ccacatccat cacacaggtt
    16561 gtacggcctt gatggacaca ttctccttta atggtcaata catcgtcgag ttttcctgcc
    16621 ttaaggtagt tgatagagga ttggagtgtc accccatcaa gtcccagcga gataaccacc
    16681 aaaccactga tttggtcaca tagcgtgaat agatagccac catgggcatt gccatagtag
    16741 ttgagcgacg agttcactac tttggtcgtc accacaacgt gaccatctct cattttttca
    16801 atttcgtaat tttcaaaggc agatatagcg tcaaaatgaa agtctttcat cgtttcctcc
    16861 tgatatttca aacgacacta tgatactact ttttatagga ctgtgcaagg agaaagctcc
    16921 tagtctagta aaattccgac atgttccaca aagcgcataa aggctgtctg cccttgttct
    16981 gtctgcttgt agactcctgc atcctcaagt acacgcgcaa agatagcacc cacagagtcc
    17041 ttgacgattg caagggcttt ttctttatcc gttaggtctg gatgttggga tttgagttgg
    17101 tctgcccact cctgatgata atcggcaact gtaacagctt ctcctacaag atagctcgcg
    17161 acttgctcca cttcttcttt cagacgtggt ggcaagattg ccaagcccat gacctcaatc
    17221 aagccgatat tttccttctt gatatgttgg acatccttgt ggggatgata gataccatca
    17281 ggatactctg ctgaagtctg attgtctcgc aagaccaagt ccaactcaaa ctgtccatcg
    17341 cgtttgcggg caatgggtgt gatagtgtga tgcggtgtcc tgtctgtctc tgccaaaatc
    17401 tgcactgcag gatctgaata ctggcgccat tcctgcaaaa tcttatcagc caaattgatc
    17461 aaatcctctt tggaatccga agtcaaacgt aggacagaca tgggccactt gacaattcca
    17521 gccttgacct gctcaaaacc agcaaatcgg aaggcctttt gcaagggagc caattccata
    17581 ggaaatacgt gacggcctcc ctgataatga tcatgagtta gaatagagcc ccccacaatc
    17641 ggcaggtcgg cattagatcc agcaaaatat cctggaaact ggtctacgat agccaacaga
    17701 cgttcaaaac tctgacgact aatggccatg ggacgatgct ggccatctaa aaagatacaa
    17761 tgctcattaa agtaagcata gggcgaatac tggaaacccc attcctgacc aaccatttca
    17821 aaacggataa tacggtgatt gctacgagct gggtggttaa ctcgaccatg gtagccctca
    17881 ttctctagac aaagctgaca ctgaggataa ttactagctt gcaccaactt ggctgccaca
    17941 atctctttcg gatccttttc aggcttagag agattgatgg taatttcaag ttctccataa
    18001 tcagatggaa cacgataagc gatattttta gcaatggcct tgagtttgat gtagtcattt
    18061 ttctgactga gttgataaaa atcctctatc gcttgctcag gatagtggac ataggtttcc
    18121 cagaagtcac gattgacctg actcggacaa ggagtcacca agtccatcag ttcagtacca
    18181 aggatttcac gcgcagtctg actatcctca atcgtctcta atcgaacggc ttcctcaact
    18241 agctggtcct tgaggtcaat caatttatcc agattggtct caacttccaa aacaccttct
    18301 cccactcgtg ccaaaacacg attggtcagg tagattcgat ccatttcctc aaatgaactt
    18361 tcagaaatga catgtgttac aaatttatct actaaggtca ccatagagcc tccttttgac
    18421 tagtcaagga cgtgagtgcc acctgcaact tcagcgatat agaagcttgg agcgtatcca
    18481 actacttcct cgtagtgttt gcctacagtt tccttaaagg cctcaacagt atctttttga
    18541 accaaggcaa tggcacagcc accaaaacca gcccctgtca tacgagcacc gagaactcct
    18601 tcttgtgccc aagctgtgtg aacaagagta tccaattcca aaccagttac ttcataatca
    18661 tgctccagag aaacgtgtga cgcattcatc aaacgaccaa atgtttccaa atcacctgct
    18721 tgaagggctg cttgagcttt aagggtacgt tggttttcaa gcacagcatg gcgagcacgt
    18781 ttcaaacgat tttcatcttt aatcaaatag ctatattggt caacggccca ctcgtccaat
    18841 tcacccaggg tctgaatatc caaggcaact tgcaattctt ccactgcttt ttcacactca
    18901 gcacgacgtt cattgtattt agagtccgcc aattcacggc gtttgttggt gttcatgata
    18961 acaacgacat tgtccttcaa atcaagtggc accaaatcat actctaaggt gttggtatca
    19021 aggtaaatag cacgttgatc ggcccccata ccaatagcaa actggtccat gataccagag
    19081 ttgactccga taaagttgtt ttctgtttgt tttccgattt taaccaaatc gagacgctct
    19141 aattttaaat caaagagatg ctctgccacg actcctgtca agagctccaa ggatgctgaa
    19201 gaagacaagc cagcaccatt tgggatattc ccataaacat aaaaatcaaa acctttgtca
    19261 atcacgtgcc cagcttcttg caagaaatga aggacacctt ttggataatt ggtccagttg
    19321 tgctcttttt caaacttgag gtcagcgaga ggcacttcga taatgccctt gtcctcaaag
    19381 ttagctgagt agaaacgcaa gacttggtcg tcacgcttac gagctgcacc gtaagttccc
    19441 aaggaaatag cagcaggaaa aacgtgccca ccgttgtagt ctgtgtgttc accaatcaaa
    19501 ttaatacggc ctggtgaaaa gaaggtttgg tctgcttctt gaccaaaaac agcaagaaag
    19561 tctttgcgaa ggacttcagt agtaagatgt tgtgccatat gaattctcct ttgactgtcc
    19621 gttaagccat cttaacgtgt aatcgttttc tttctattgt atccaaggaa tttcccaagg
    19681 tcaatccttt ttactaaaat tttactaaaa tatcagtaaa aagaagaaaa atatgatata
    19741 ctaacctaat caaggaggat ttatggctac cttaaaagac attgcacagc tagcctctgt
    19801 ctcaatcgcg accgtatccc gtgtcctcaa ccgcgaccag agcctatctg ttacagaaga
    19861 aaccagacac cgtattttaa ccgttgctga agagctaggc tacaccaaac acctcaagac
    19921 aggcgagtcc cacaagccca agcaaaagat tgccattatc caatgggtca gcgaacaagg
    19981 ggagctagac gacctctact actaccagat tcgcctagga atagaaaaaa gagcccaaga
    20041 gttggactat gatatcttgc gctattttaa tgaccatcct tttaccctaa gcgaggaagt
    20101 gattgggatt ctctgcatcg gaaaatttag ccgagctcag atttctgcct ttgaagaata
    20161 ccaaaagccc ctggtctttc tagacagtga tacactttcc ctggggcata cttgtattat
    20221 tacggatttt tacactgcta tgaaacaggt tgtcgattat ttcctcagtc aagggatgga
    20281 ccgcatcggg attctaacag ggcttgagga aacaacagac caagaagaaa tcattcagga
    20341 caagcgtcta gaaaacttca aaaactacag tcaagcgagg ggaatctatc atgatgaact
    20401 ggtctttcaa ggaagattta ctgcccagtc tggctatgac ttaatgaagg aggccattca
    20461 gagcttggga gaccaacttc cgccagcatt tttcgcagcc agcgatagtt tagctatcgg
    20521 tgccctccgt gccctccaag aagctggaat cagcctgcca gatcgcgtca gcctcatttc
    20581 attcaacgac accagtctga ccaaacaggt ctatcctccc ctctctagta ttacagttta
    20641 tactgaagaa atggggcgag caggtatgga tattcttaac aaggaagtcc tccacggtcg
    20701 caaaattcct agcctgacca tgctgggaac cagactgaca ttaagagaaa gtaccctaaa
    20761 tcaagaatag gataacataa aaaacgaata gagttctaaa actcctattc gttttttatt
    20821 cgattacaat catagactta attgtcttac gttcatccat atctttatag gcttggtcga
    20881 tatcttccag tttataactt gaagtaaaga cgcgacctgg attgatatca ccatcaagga
    20941 cggcttttag taaaaattgc ttatcgtatg ttgtagcaga agctgcccca cctgctacag
    21001 agatattttg cataaatgtc gaaccaagag cacgattatt atagtgtggg actcctacaa
    21061 agcccatacg ccctccatta tgaagaacac ctagcgcctg ttctatagca gcctccgtac
    21121 caacacattc aagtgctgcg tctgctcctc cgccgaggat ttcacgcacc ttggtaattc
    21181 cttcttgacc acgttctgca acaacagctg tcgcacctga ctccatagcc atcttttgac
    21241 ggtcttcatg acggctcata aggataattt gtgatgctcc acgcatctta gccgcgatga
    21301 cagcacattg accaacagcc ccatcaccga taacaacaac cttgtcccct ttttgaacat
    21361 ttgcaacacg cgctgcatga tagcctgtcg gcatgacatc tgcaagagtc aaaagggact
    21421 tgagcatccc ttctgtataa tcagaaggtt gaccagggat tttaaccagc gcccagtttg
    21481 catagtggaa gcgaatatat tctgcctgaa aatcaccccc caaattatta ccaatatgat
    21541 tgtcgcaaga accgtcaaat ccagcaagac aggcatcaca ctcaccacat ccatgtgtaa
    21601 aagggacaat cacaaaatca cctggtttca ccgtcgtaat ggcttcccca gcttcttcaa
    21661 caatcccaat cgcttcgtgt ccactatttt tatgtccagc tttcgtttct ggattacggt
    21721 acctccataa atctgaacca caaacgcacg cacgaaccac acgaataatc acatcatccg
    21781 cttctattat ttgcggacgt tcaatgctag caagtccaac ctgacctgcc tttgtatata
    21841 ctgctgattt catttaaaat tttccttcct tataaagttt aattttgaga tttaaacgat
    21901 ttaaagctgt ctgtagctga gacaagcgct cctctaattt ttgcttttcc tcttctaaaa
    21961 taccaagcct ctcctctctc gtttcatctc ccttttggta gagcgacata tagtcaacta
    22021 aactatctac agagacaccc gccgaacgaa aacacttaat aaattccagc gcttcgatat
    22081 cctgatcttg aaaatcacga atcccagtag cagtacgagt aatcggtggc acaagaccaa
    22141 cccgttcata ataccgaatc gtatccgctg aaattcccaa caaatcactg gcagatttaa
    22201 tattcacacg ctaacctcct ctcatttcat tcactgaatt cacgctattc taactcactt
    22261 atcttattat ataactttga gttgactcca agtcaagcat tttgtatcta atcgaaaaat
    22321 ttttatcatt aacaatcata tatctggagt ttatacaatg ctcttctctt accaattttt
    22381 gaaatattta aataataaag aaattactct attccaaata agatagtacc caagtatttt
    22441 tcactttttt ctaatgttga tgctcataac tccgttccaa gtcacacacc tttcgcttat
    22501 gggtttggtg agtttctagg tcagcatcaa tttcaatggt aatattttga aaaccacaat
    22561 cttttaggaa aattcgaata gactctttac aagtttccat atgttccatt tcttttagac
    22621 aaacatgtac aatggcattt ttttccaaag catccatagt ccagagatta agctgattaa
    22681 ggctggccac attgtccaat cgctccaggc cactctttac ttgcttgata tcaagacctt
    22741 ctggcacagc atccaagaaa atcttgagtg tagaccaaaa acgtggaagg gcttttgaaa
    22801 gaataaagaa agaaatgaca agggacaaaa gaggatctag gatataccag tccgtaaatc
    22861 gaagaacaat cgccatcagg ataacagcta cccaccctag cgtatcttcc agaaaatgca
    22921 aactcagaat agactcattc tttgtctttc ccttaccaac caccagactc gctaacagat
    22981 tgatagtaat cgcaataatt cctaaccaga gaatcccctc atcattgact ggttgcggat
    23041 gcaaaatctt cgtgacattt tccaaaatga ctagaacaga gcccgttacg agaatcacag
    23101 ctgttaccaa ggctcctagc aggctaaacc gcttatagcc caaggtgtac tgattgtctt
    23161 cttcacgatt ggagattgtt tctagaaaag ctgatattcc aattgcaatc gcatctccca
    23221 agtcatgcac agagtcagca agaacagcgc tagaaccaaa tactccacct gcaataaact
    23281 caacaatggc ataagtcaaa tttaagaaaa aagccaccca aacagcatat tttgccttca
    23341 tatttctcat tcctttgtta taatagattt atgaacacct tgttcattat cattatccac
    23401 taaaactcaa agaaaggata gaagcaaaac gtcagcttta ttcagttctg aacaatttgc
    23461 cttaagtgtc catatgacta acattgaccg ccgtatcagc aaaaccaaaa aagccatcta
    23521 tcaagctttt atacaacttt tgaatgctaa gggctacgag gccactactg ttcaggatat
    23581 cattgatctc gcagatgtgg gaagatccac cttttactgt cactatgaaa gtaaggagct
    23641 tcttctggac cagctctgcc gctacctctt ccatcatctt tttgaaagag agcaagccat
    23701 ttcaaccgag gactacctcg cccacctctt tctccatttt cagaaaaacc aagaccatat
    23761 caccagtctg ctattttcca aaaatgacta cttcctccgt caactccata aagagctaga
    23821 acaccatgtc tattccgtgc tagctgataa tttaaaagaa gcccacccta atatgcctac
    23881 ttcttacctc caacacttgg tcgtgtccaa ctttatcgag acattgacct ggtggctcaa
    23941 aaaaggtcaa gatttcatag gccaggaagt tgtccaattt tatctagacc ttctcattcc
    24001 taaaaattga atatagagta aagctcagtt gtcttatttc taggttactg agttttttat
    24061 cttttcaaca acaaaagagg acccgccgat cctctttttc atactataaa tccttgatta
    24121 tcaactatat ctgttttaat cgaaatctca aaacagcact ttcaaacatc ttttcctagt
    24181 taagtaaatc agtattctgc ttagctgcct tgctccattg ataccaacca actagactgt
    24241 taatgagata aattagatat ttcccttgaa tttgcaggct ttctccccac cagagataga
    24301 ttgaaaaaac attggtagcc gcccagaata tccactgttc acggtaaaca gctgtcatga
    24361 ggatttgccc taccccattg gttgcatctg tgattgaatc acgataggga cgattggcac
    24421 caatagactg ataaatgaag ccaaaggcca accaccaaag cacactaatg gaaagatact
    24481 ttgtccagcc cttgccgtcc agtttacgcg cgacaaactc ctgcttttcc ttcttaaact
    24541 gtgcctgata aatccaaact agaagtccaa ttggctgcat gactgtgaag taaagtgtcg
    24601 tcagcacctc accataaaag cctttctgta gggccaaaat aaggtaaata acagagttaa
    24661 tcaagccaaa aagataatta cttgctcgac cttccgatac aaagattaca cagataatcc
    24721 ctgtcaagct acaaatcatc ccaatccagt caacaatacg atgttcgtaa accaactcca
    24781 gccagagagg aaaacttcct aaaaccagca aataaatcca ctgggcaaaa ctacgatggg
    24841 caaagaggtc atcccagata gccttcatag ttcctgaaaa tcctaaatca gccatagccg
    24901 caaccatacg acggtaacca cctgacattt cacctagggt tgttttgata ttttcaattt
    24961 tcttttgcaa ataagtatgc atcatttctc cttttgtttt taaagagccg tgtctggata
    25021 gactttcgga cgcaacgctc tattagataa tgaactgcct atacacaaga tttctaacct
    25081 tagtcgacat gagctaaaac ctcttatttg ttaagtagtt cacaaaatat tatacaccta
    25141 ttttatgaat agtcaactgt ctttacagta aaattttaga aaatcatgaa aattttctct
    25201 ttctttccat tttaagtgac attcagtcat tctcacatca aaaaagccca gacgaaattg
    25261 tctgagcatt cttttatcta gtcgtttaag gaagttgagt tcagtatgtt taaagtctct
    25321 gtcccatcat ttcttcaaca aaccttgttc ttggagaaac tccttggcta cttgctttgc
    25381 tgacttgcct tcaacaccga cttggtagtt gagctggctc atctggcttt ctgtaatctt
    25441 accagccaat gtattaagaa ctctttccaa ctctgggtgt ttcttgagaa gagcttcttt
    25501 catgagtgga gccccttgat aaggtgggaa gagttgcttg tcatcttcca agacctgtaa
    25561 atcataacgc tccaattccg catcagtcga ataggcatcc gtgatttgaa tatcccctga
    25621 ctgaattgcc tgataacgaa gagctggctg catagtcgcc acattgagat tgagaccata
    25681 cattgattgc aagcccttat ttccatcttc acggtcgtta aactcaagcg taaagcctgc
    25741 cttcagctgc ccttccactt ttttcaaatc cgaaatggtc ttcaagccat attcttgcgc
    25801 aatctttttc ggaacagcta cagcataggt attttgataa gacataggtt tgagataggc
    25861 tagatgatcc tgcttggcaa tgctatcacg cgccacttga taaacctgct ctggctcatg
    25921 actcaccttg ggtgatggtt gaagcaaact ttcagtcacc gtaccggtaa attcaggata
    25981 aatgtcaata tcaccttttt tcagagcttc ataaaggaaa cttgtcgtcc caaaattcgg
    26041 tttaacagtc gcagtcatgc tggtattttc ttcaatcagc aatttataca tattagccaa
    26101 aatttctggt tctgggccta ttttcccagc aataatcaag ttttccttct ctttttgagc
    26161 caaaagggct ggactataag acagacccag taataaagcc accaaggcaa aaccagagaa
    26221 aatcgtccgc aatttcgctt tttccattac ttttagtagg aagttaaagg caatagctag
    26281 cactgcagaa gaaagggccc caatcaaaat caaactggca ttattacggt caattcccaa
    26341 caggataaag gaacccagtc cccctgcccc aatcaaggtc gccaaggtag ccgtaccgat
    26401 aatcaagacc gctgccgtcc gaattccaga catgataaca ggcatggcaa gtggaatttc
    26461 aaacttcttg agacgctccc atctggtcat cccaaaggca atcccagcct cttgaagact
    26521 cggatcaatt cccttcagcc cagtaatagt attttgtaaa atcggaaaaa tcgcataaat
    26581 cactagagct gtcaatgccg gtaaagtccc aattcccatc aagggaataa agagtcccaa
    26641 caaggccaga gacgggatgg tctggaaaat ccctgcaatc tgtaagaccc aatccgccaa
    26701 cttctcatga tagcgaagaa aaacagccaa gggaatcgca agcaaaatag ctagtaacaa
    26761 ggtcaaaagt gacaactgca aatgttgaga tagagctgtc aaccaatcac taaaacgatc
    26821 ctgaaaagtt gcaattaaat tagtcatgaa cactacctcc aaacaagtct gctacaaagt
    26881 ctgttgcagg cgcttttaaa attgtctcgg gattcgctac ctggcgaatt tctccatcct
    26941 gcaagacagc aatacggtcc gccaacttca aggcttcatc cgtatcatgg gttacaaaaa
    27001 tcgttgtcat cccaaactct ttatgcaatt cttttgtcag aacctgcaac tgttttctcg
    27061 aaatagcatc caaggccgaa aagggttcat ccatgaggaa aatcttgggc tgaccaatca
    27121 tagctcggac aataccgacc cgttgctgtt ctccaccaga taattcacta ggtaagcgat
    27181 gcccatactc ggctactggt aaaccaacct tagccaaaag ctcttctgtt ttcttcgtaa
    27241 tttcttcctt gctccacccc ttcatttcag gaatgagagc aatattttcc gcaactgtta
    27301 gatttggaaa aagagcaata gcctgtaaaa cataaccagt agaaagacga agttcacgct
    27361 catcatagtc tttgatgcgc ttcccatcca tataaatatt tccatcagtt ggttccaaaa
    27421 gacggttaat catcttgagc atggtcgtct tacctgaccc agaaggccct actaaaacca
    27481 taaattcccc atcctcaatc tgtaagttga catctctcaa gacatccttt tctgtgtagc
    27541 atagtgctac atttttgtat tcaatcattc tttgtcctca tttaaaactt ccctcgattg
    27601 gtcaagtctt ctaccttagg catgacttcc ttattatccc aatgctccac aattttcccg
    27661 ttctttaaac ggaagatatc gtactgggca taagcaacgc catcaatctg agtctgacca
    27721 tagctaacca catagtttcc ttgtcctaag agttggaaaa caaagtcaaa agtgacacta
    27781 tattcagcca catagttttt ataagcagca cttccttgtc caatatcatg attatgctga
    27841 atcaaatcgt ctgccacata atcactccac tgctctagct ccccattttg gaaaatttct
    27901 gtcaagaaac ggcgaaccag ctttttattt tctgctttct tgtccaaatc cttgatttca
    27961 aaatctccaa aaatttgatc tagttggtca ttttcaggtg ttcgatagta gtcaatgaca
    28021 tcccaatgct caacaatacg accattctca tccgcacgaa aagtatccgt cgtcacccat
    28081 tgagcttctc caccattcag atattgatga acatgaacaa agaccagatt gccatcctca
    28141 atggtgcgga caatcttaat ctgacgctct ggatgacgct caaagaaatc tgcaaagaag
    28201 gctgcaaatc cttctttccc gtcaggaaca cctgtcgaat gttggatata ggtagcccct
    28261 acagactggg cttgagcctc agcaactcgt ccgtcttgaa tggcatggat gtataggttg
    28321 tgagcatttt tcacttgttg tgacatattc taaacctcat ttcccttctc tttcagattc
    28381 gccaaaattc tttcttgaaa accttcaaat tggtgaattt cttcctctga aaatcctttg
    28441 taaaagatag tatccaattt ctgactgaca cgatgcccca cttctttctg ggacttgcct
    28501 aactccgtta aaactaaata cttcttacgc ttgtcttttc cacacggact aacaattaca
    28561 agcttttgtt cctctagctt ttttatcata gtcgtcagcg tattattcgc aagtccagtc
    28621 gcaagcgcga tatctgtcgc agttgcgcag ccagtttcac tattccataa aaccgctaaa
    28681 atcttgccct gttcacccct ataaagagcc tcaggatctt gactcagtaa cttttgaaaa
    28741 atccgcccat tcaacaaacg aatatgatgg gctagcaaat gaccatcttt cataacacct
    28801 ccaatttatt tcgatatcga aatgaataaa acaattgtaa cactcatcgt tctaactgtc
    28861 aactatttcg atttagaaat aatttttgat aattatccac accaccatac tccggctcaa
    28921 ctaactttta acgagagttt ctaaactcct tcgtcctcca gtctacaaaa gccttccatc
    28981 cgtactatcc tatattttat gaggggacac atttttccta tcagaccatt tattttaaag
    29041 atagaagtaa atcataattg cttccatctg ttcttttata gtatattgaa gttggactag
    29101 ggcactgtat cttctaaaac attgatagaa agcgatttga atttcccaat caatttgttc
    29161 gtctttatag catttcgaaa ctggaatagg acaccatgac tgctaaaaga tttctataaa
    29221 ttcatttgat ttcctcaatc aatttgttca tatcttattt cattccgcta taatttcacc
    29281 ttaccctatc tttttcgtag cacccttcaa acagcctatc ccctaccgtt tgacgattcc
    29341 tcacttcact ccacttccat tacagaagtt tcttcactac tatggtctcg gctgacttct
    29401 catgattcct tgttactact atttgaacgc tcacgagata ggtcttataa aaaatgcttt
    29461 gatccacaat ggaatcaaag cattttaaaa agttcctcat acataagtgc agaagtcgca
    29521 gttcctctgt acttggcttc ttctcttttg ataaagcgag ccaagttgag caactcaggt
    29581 gctggatgtt tgggatttag gagcaattca cgattgacca ggcctgagag acgaactgcc
    29641 tgcaattgct catttgtagt aggcagtttt ttagtagtct ctaggagagc agcaactaaa
    29701 tcttcactca aatcatgtcg agcatgattg taaagatctt ttataaggct ttctaggttt
    29761 ggttctgcca tccctaccac ctcccttatg gtttaataat gtttaatcaa atcaaccgtt
    29821 gaacgatcca atttcttcac caaggcttgt aagaaagctt gcgcttctag gaagtcatcc
    29881 attgcataga gggtttggtg agaatggata taacgagcgc agacaccgat agttgttgat
    29941 gggacaccac catttttcag atgagctgca cctgcatctg ttccgccttt accacagtag
    30001 tattggtact tgataccagc ttcttcagcc gttgtcaaaa ggaaatcctt catccctggg
    30061 agaagcaagt gacctggatc atagaaacga atcaaggttc catctccaat cttgccttga
    30121 ccaccgtaga catcacctgc tggtgagcaa tcaactgcga ggaagacttc tgggtcaaac
    30181 ttggttgtag aggtatgagc gccacgcaga ccaacttctt cttggacgtt agaacccaga
    30241 tagagttcat tgccgagttt ttgacctaat aaagcttcag ctagctcgct taccatgagg
    30301 acaccgtagc ggttatccca agcttttgag atgatatttt tttcattggc tgtcaaaatt
    30361 gcagaactat ctggtacgat ggtatcacca ggacggatgc caaaactttc tgcctcagcc
    30421 ttgtccgcaa aaccaccatc aaaaacgata tcggcaatgg ctggcatggt tggtcccccc
    30481 tttccacgag tcaaatgcgg aggaacagaa cctgaaatca caggaatttc atgaccatca
    30541 cgagtcaaga gtttgaaacg ttggctgcta accaccatgg ggttccagcc accgatttct
    30601 acgacacgga aggtaccatc tggcttgatt tcgctgacca taaaaccaac ttcgtccata
    30661 tgagaagcga ccaagacgcg cggtgcatcc acagcttctg aatgtttgat accaaaaata
    30721 ccacccaagc catctgtcac cacttcatcc acatgcggtg tcaacttttc acgaagataa
    30781 gcacggacag gcgcttcatg acctgagact gcagcaagtt ctgttacttc tttaattttt
    30841 gaaaataatg ttgtcatttc agttccttct ttctttcatc cattttacca ctttttatag
    30901 gagaaggata gtgggaaggt ggatttctaa gttagtatct tagtcctgct ctatcttaga
    30961 aaaggatagt attctcttgc atgtagtgca aaatctagta aacattccaa aattaactcg
    31021 aatatttatt tccaaacaaa aaaacaatac accatcaaag ttgtttggat ttttcatgaa
    31081 atttacagaa aatagttgac ttccctttct tctttcttta aatatatagt tggttgagtt
    31141 tggaatagta cgctgtagct gctaaaacat ttctagaaat taatttgact tttctaatag
    31201 agttgttcat atcttatttc aatttactat agtacaaaac tagaaaagga aaaaatcatg
    31261 accaaaacaa ttcttgttac aggtgggact agctacattg gctcccatac cgttaaagct
    31321 cttttaaatg ctggctatca ggtgcatgtc ctcgataatc tctccacagg aaatcgagcg
    31381 gctgtggata gtcgtgctag ctttaaagaa ctggatgttt atgatgctag cgccttaaag
    31441 gcttacttag aagaaaatca gattgatgct gtcctccatt gtgcaggtga aattgttgtg
    31501 agcgaaagta ttgaaaatcc aagtaaatac ttcactgcca acgttgctgg tatggaccaa
    31561 gttctcaaag tcttatctga agttggcatt caaaaaatca tgttctcttc gactgcttct
    31621 ctctatggaa ataactgtat tgacaagccg gtgactgaag ataccctgct cgaccctgtc
    31681 aacccttatg cagagacaaa actgatgggc gaacgaatga tttactggat ggccaatcgc
    31741 tacgactgga aatatgttat tttccgttac tttaatgttg ctggggctga aatggatgct
    31801 tcaaacggtc tgcgtgtgaa aaatccaact cacatcattc caaatatcaa caagaccgca
    31861 ttgggacaac atgatagctt aaaaatattt ggagatgact acgatacacg tgacggttca
    31921 tgtattcgag attacattta tgtcttggac cttgcatagg ctcatgttaa aggaatgaac
    31981 tacctatttc aagaagacag ttcttctcaa atctttaact taggaactaa aaaaggctat
    32041 actatcaaag aaatctttaa aactgctgaa gaattactaa attaaaaaat cccacacgag
    32101 attgttgctc gacgtgctag tgacccagcc agtgtcctag cagatgcttc aaaagctaaa
    32161 caatatcttg attggacggc tagctactcc ctcgaagata ttattttatc agattaaggt
    32221 aaaaacattt tagaatagga taacaaagga gaaagtcttg ttgctctctc cttgttgtat
    32281 ttattaaatt gtcagaaatt ttattgacag attagaaaaa taatgttaca tttatatccg
    32341 caggtatctt tcgataccaa atctacatga aaggacgggg tatgaaactt tctcattatt
    32401 taattggctt acttctactc ctagtctttc tctctattag cattgggacc agtgattttt
    32461 catggggaaa gctatttgat ttcgaccagc agacctggct cctctttcaa gagtcccgtc
    32521 tcccaagaac tatcagtatt ctcctgactg cctctagtat gagtatggca ggccttctca
    32581 tgcagactat tacccaaaat cagtttgctg caccgagtac agttggaacg actgaagccg
    32641 ccaaactggg aatggtgctg agcctttttg tctttccatc ggctagtctg acccaaaaga
    32701 tgctcttcgc ttttatttca tccatcgtat tcaccctctt cttcctagcc tttatgacca
    32761 tttttactgt aaaggaaagg tggatgttgc ctctgattgg gatcatctat agcgggatta
    32821 tcggctcagt cacagaagtt atcgcctatc gtttcaatct ggttcagagt atgactgcct
    32881 ggacccaggg ctccttctcc atgattcaga cccatcagta tgagtggctc ttcttaggcc
    32941 tcatcatcct gataaccgtt tggaaattat cccaaacctt caccatcatg aatctaggga
    33001 aagaaaccag cgagagtttg gggatttcct actccctact tgaaaaactg gccctctttc
    33061 tggtggcgct aacgacaagc gtcaccatga ttaccgtggg tggcttacca tttctcggag
    33121 ttatcgttcc caatcttgtt cgcaagcgct atggagataa tctaagtcaa accaaactca
    33181 tggtcgcact ggttggtgcc aatctagttc tggcttgcga tatcctatcc cgagttctga
    33241 ttaggcccta tgagttgtct gtcagtctct tgctaggaat catcggtagt ctcgtcttta
    33301 tcctacttct ctggagaggg ggacgaaaag atgcagacta aaagcaaaca taccaagctc
    33361 ttctggattc tcattattct tgccatcgga gcttgtcttc tctacttttg gcccatcact
    33421 cacttgtcag cctttgcttg gaagttgcgt tcccaaaaga tcatcgttta tctcttggta
    33481 gccatcgcga ctgggatttc gaccattagt tttcaaaccc tgacggaaaa tcgcttcctg
    33541 acgcctagta ttttgggaat tgaatccttc tacgtcctac tacaaaccct actactggtt
    33601 tttgaaagca agtttcttca acttggcaaa tcccctatct tagaattcct agtcttactt
    33661 cttgtccagt ccctcttctt tctcgcctta caaggttact tgaagacact gatgaagcaa
    33721 gacctggtct tcatcctgct gatctgtcta gcgctcagaa gtctctttcg aaatatcagc
    33781 accttccttc aagtcctaat ggatccaaac gaatacgata aactgcaaaa tagtcttttt
    33841 gcctcctttc aacatcttaa cacttccatc ctagccatcg gttctctgat catcctcgct
    33901 ttgacaatct ttttctttcg aaaagcagtc gttctagatg tcttgcacct gcaaagagaa
    33961 acggctcaga tattgggact cgatgttgaa aaagaacaga aagagctcct ctggggaatc
    34021 gtgcttttga cctcaacggc cactgccttg gtaggaccta tggccttctt cggctttatg
    34081 ctggccaacc tcacctacct gattgtcaaa gactatcagc acaagttact ctttatagtg
    34141 gccattctgg ttggatttat tagcttaacc ttggggcaag ccttgattga acgagtcttt
    34201 gcactggaaa ttcgtatcag tatgatcatt gagagtgtgg gtggcttctt attctttatc
    34261 ttactatata ggagggctcg tcagtgaaac tggaaaacat tgacaaatcc attcaaaaac
    34321 aggatatttt gcaaggcatt tcgcttgaag tcagtcctca aaaactgaca gcctttattg
    34381 gtccaaatgg tgctggaaaa tcgactctcc tctccatcat gagcagacta accaagaaag
    34441 atcagggagt tctcagtatc aaaggacgtg aaatcgagag ctggaattcg caagaactgg
    34501 cccaagaact aaccatccta aaacagaaaa tcaattacca agccaaattg actgttgaag
    34561 aactggtcag ttttggacgt tttccctaca gccgaggtcg acttagatca gaagactggg
    34621 aaaaaatccg agaaactctg aactatttgg aactgaccaa cttaaaagac cgctacatca
    34681 atagcctgtc aggggggcaa ctccagcgcg tctttatcgc tatggtactg gcccaggata
    34741 cggactttat cttgctggac gaaccactca acaatctcga tatcaagcaa agcgtcagca
    34801 tgatgcagat tcttcgacga ctggtggagg aactcggcaa gaccattatc atcgtcctcc
    34861 acgatatcaa catggccagt cagtatgcag atgaaattgt cgccttcaag gacggccagg
    34921 tctttagcaa gggaagaacc gatcaaatca tgcaggctga cctgctcagt caactttatg
    34981 agattcccat cacgctagct gatatcaata acaaaaagat ctgtatctat agctagtaac
    35041 ataaaagctc aagttagaga accttcagtc tcttagtcaa taagattaag agactcccta
    35101 aatcgttatc acattttaaa aaggagaaat tatgaaaaca tcccttaaac tttatttcac
    35161 tgccctagtg gccagcttct tgctcctact tggtgcatgt agtacaaact caagcactag
    35221 tcagacagag accagtagct ctgctccaac agaggtaacc attaaaagtt cactggacga
    35281 ggtcaaactt tccaaagttc ctgaaaagat tgtgaccttt gacctcggcg ctgcggatac
    35341 tattcgcgct ttaggatttg aaaaaaatat cgtcggaatg cctacaaaaa ctgttccgac
    35401 ttatctaaaa gacctagtgg gaactgtcaa aaatgttggt tctatgaaag aacctgattt
    35461 agaagctatc gccgcccttg agcctgattt gattatcgct tcaccacgta cacaaaaatt
    35521 tgtagacaaa ttcaaagaaa tcgccccaac cgttctcttc caagcaagca aggatgacta
    35581 ctggacttct accaaggcta atatcgaatc cttagcaagt gccttcggcg aaactagtac
    35641 acaaaaagcc aaggaagaat tggccaagct agacaagagc atccaagaag tcgctactaa
    35701 aaatgaaagc tctgacaaaa aagcccttgc gatcctcctt aatgaaggaa aaatggcagc
    35761 ctttggtgcc aaatctcgtt tctctttctt gtaccaaacc ttgaaattca aaccaactga
    35821 tacaaaattt gaagactcac gccacggaca agaagtcagc tttgaaagtg tcaaagaaat
    35881 caaccctgac atcctctttg tcatcaaccg tacccttgcc atcggtgggg acaactctag
    35941 caacgacggt gtcctagaaa atgcccttat cgctgaaaca cctgctgcta aaaatggtaa
    36001 gattatccaa ctaacaccag acctctggta tctaagcgga ggcggacttg aatcaacaaa
    36061 actcatgatt gaagacatac aaaaagcttt gaaataagcc acttcaaact caatttaata
    36121 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa aacactgttt
    36181 tgaggttgca gatgaaagct gatgcggttt gaagagattt tcgaagagta taaaattttg
    36241 acattctaaa acgcatccta tcaagttcac tcaaacctga taggatgcgt ttttatcatt
    36301 ttgaaatcta tttaccccac ctcattcccc ttcttgattt cgtttaaggg aaaagtggtc
    36361 tggaacgggg tccttacctg ttttcgacca gggatgacaa cgtaaaatcc gagccaagcc
    36421 catcaatacc cccttaaaac catgtttttc aatagcctga atcatgtagt tggaacaagt
    36481 cagctcaaag cgacaagagg gtggaaagac tggtgagata aaacgttggt aaaagcgcac
    36541 aagcgctatt aaaattcgtt tcattatttc ttagttacag ccatggtgtg tagttggctg
    36601 atttcttttt tattaagacg acgggattct cctggacgga gtcctgtcaa gtctaggtgt
    36661 ccgaaacgag tccgagacaa cttatctact tggagaccaa cagcttcaaa catcttttta
    36721 acctgatggt tacgcccttc atggatggtc aactgcacca cagagcgatt tttgactggg
    36781 tccactttga gaatttcata aacagctggc ttggttttct taccatcaat ctcaagacca
    36841 cgggtcaagg ggcgaagatt gtccttattg gccacacctt taacacgcgc gacataaacc
    36901 ttgtcaatct cattacgagg gtgaatcatc tcgtctgtaa agtccccatc attggtcaaa
    36961 atcaagactc ctgatgtatc ccagtccaaa cgacccacag ggtaaatgcg ctctttgaca
    37021 ttgggcaaga ggtcgacaac cgtcttgcga cccttgtcat ctgttacact ggaaatgaca
    37081 ccgcgtggtt tgttaagcag ataatagacc ttttcttcgt tgtagatagg ttgaccttca
    37141 acttcgacct tgtcgcctga cttgatagtg gttgctagtt cacgcaccac ttggccgtta
    37201 actgtcacca aaccttgctt gatcagctct tctgcttttc tcctactggc cacacctgcg
    37261 tgggcaatat acttattgat tctcatcttc ttctatcctt tcaccaaata attggctttc
    37321 ttgggcttga atctcaagct catcaatcac tggtaattct tctaaatggt ttatccccat
    37381 gtaatctagg aaataatccg tagtcacata gaggttgggg cgccccaata cttccttttt
    37441 cccgtcttcc tttatcaggt ccaaagcttg caactttgcc aaggctccac tcgagttaac
    37501 cccacggatg gcatcaattt ctatccgcgt aatcggctgt ttgtaggcaa taatggacaa
    37561 ggtctcaagg gcagcccgag acaagctctg gttgataggc gccttagagt attccttcaa
    37621 aatctctgca aattgaggct tggtcaccaa tctataagca ccacttgtct caatcaaagc
    37681 caaactggaa tctgggtcct tttcatactt ctgggctaat tttcctaaac tttgctggat
    37741 gcctgtcggt ggcagagaga ggagttcagc taactggcgg acccgaatcc catcttcacc
    37801 cgctacaaac aagagcgctt ctatttttgc taaagtactc atctttcctc tctatcaagt
    37861 ctagctttga ggcacttgac tttcttcctt cttttccatg agatagatat ctccaaaact
    37921 ctcctcttgc acgaggatca gctcctgggt tttgattaac tctagggttg ccaaaaagag
    37981 ggtgatgacc tcttggacat tctgggcttc cttgaacaaa tcctgcaagc gcaattgatc
    38041 tcgtccaatc aaggattctt tcacaataat catcatgtcc tcaatcttat actcatcccg
    38101 caagatagtc gtgtgatttt gtgcaaactc ctcttttttc ttggctagga tatttgaaaa
    38161 agccaaaaag aggtcaatgg tcgtcttgtc atgcacaagc tccgcatctt cgtaaatcaa
    38221 ctctgtcggc gctttggaat aatactgggc ccgttcttgg tgcttggctt ccaagtgctc
    38281 acccaagagc ttgaacttgc gatattcttc gatttgagag aggaggtcct gctccaggtc
    38341 atcccccaag tctgtcactt ctgctacctt cggaaggagt ttacgactct taatcagcat
    38401 gagctgacta gccatgacca tgtactcacc cgtcacttcc agacgcatgg cctgcagggt
    38461 tgagacatag gctagatact gttcgatgac ttccgtaatg ggcacatcgt agatatccat
    38521 ctggtactta gaaaccagat gcaagagtaa gtccaggggt ccttcaaaat cttttaattt
    38581 aatatccatt atctatattt ttctaaggtc aggactgttt ttaatcctaa tttttttgca
    38641 atttcgtaca aatcgacctt gttttctatt tgtcttagaa taaactgttc acgtaagact
    38701 tgagctgata aggatggaaa acctttctcc ttgacaaaag attctaactg acgaaaggcc
    38761 cactgacgag aatagggttt ccctcctctt tcaaaaagat aggtctgccc catcaagggt
    38821 tccaattctg aaagcaaggc cgtgggaatg gtgacaatcc tccgttggga agccttgctg
    38881 attcgcaaca cctgaaaatc cagattgatg tccgcaacct tgatggctaa aatctcactg
    38941 ggcaagagcc ccatttctag gattaagagc gctagcaagc ggccctctgg atggtcgctt
    39001 tcctgccaaa aagagtctag gtatagaatc tctggctttt ccgtcttctt ttcagcttgt
    39061 ttggctaatt ccaagcggta aaagctgtcc acctctcctt tttgatagag aaagtataga
    39121 aattggttac aggccgaaat ctttcgcttc tgggcgctga tttttagatt ggctagctgg
    39181 gcttggtaaa tcttgagact ggtctcagaa atccgctcac ctaccatgtc taaaaattgc
    39241 tccaaatcat acttatagga ctgcttggaa ttgacagaca agccctgctt ttcctctaaa
    39301 aaggctgaaa tcctgtctct cattggcatc gaatctcata ttccttacta aagtcatgca
    39361 agagggcatt aacggccttg aggatggact tgcgcgtaat aatcccttgg aaaataccct
    39421 ctgcatccac aaccggtaag aaggactcat ctactagctt gtgcaagacc tccgtaatgg
    39481 tgaaatcagg cgaaacaacc gctacgtccg tttttgtcat atgaacgata tccgtatccg
    39541 ccatgatttc ttggctcaag tcatgctcca tctgataagc cataatatct ctgagtccaa
    39601 tcgtcccaac aaactgtttt tcatctgtca caacgggaac acgggtatag gtcatctgac
    39661 tgagcaagag ggtcgcatga tccgcattgt gagtatcaat caacacagct agatttttag
    39721 caggggtcaa aaaagtttcc tcctgcccca acaagaaagt ctcaaactcc ttggcaatca
    39781 tcggctaaac tccttggaca aacctggata cacctcgtga tctcgtgtca aaaagtccac
    39841 tttgaagtaa ctatcatcaa tctccacacg agcatagaga cattctctga tggtacctcg
    39901 tggttgactg atagagcctg gatttagaaa gaggatcttg ccttccaacc aagcacttgg
    39961 cacatgcaag tgaccataga ggcagatagc ggcctcttcc tcctgagccc agtagtccaa
    40021 cttttgaaag ttgaaattga tgtcaaacaa gtgaccatga gtttggataa tcttggtcga
    40081 accaagctca gtcaccagac gttctgggta gccggcgtag aagtccatgt tccctttaac
    40141 aacgcggatg ccctcccaaa gtggagaatc cggacgtagt tcagaatcgc cgttatgaaa
    40201 aacggcatcg actttgccca catagcgatc acggacttct tccacaatca agctatcgcc
    40261 atgggaatcg ctcattacaa tgatggtttg ctttgccatg atggaaatac ctccaaaagt
    40321 ttcttaacgg ctaaggcacg gtgagattga ctattttttt cttccagggt taattcagct
    40381 gatgactcac ctgtctctcc tacaaggaag aggggatcat agccaaagcc attttcaccc
    40441 ttaggttcaa agttaatata acctgaccag tctgcttcaa caactaaact ttccttattt
    40501 gggctggcta cgactagggt tgtgtggaac tgagccgagc ggtccttgag ttcaaagacc
    40561 atggccaatt cgtgcaagag tttggcatta ttttcacggt cagttgctcc cacacctgcg
    40621 aaacgagctg accagacgcc tggtaagcca ccaaggacat cgactttgag accagaatca
    40681 tctgccaaaa ccatcttgcc cgttaattga gaaatggttt ctgccttaag gcgggcattt
    40741 tcctcaaagg tcatacctgt ttctgctact tcaggcaggt cagggtagtc attaagattt
    40801 tccacatcgt agcctaactt atcaaagata gctcggaatt ccttggtttt accttcgtta
    40861 cgagtcgcaa tcaacaaggt ttctctgact ttgcttgtct caaagaaatc atgaacattg
    40921 accccttctt taggcaattc tacatacaag agttgcccat tttcaaccaa gagcagggcc
    40981 ccatgacgtt gaataacttc caagtttcgt cccatttctt gattaagcat atctaccaca
    41041 aaggagaaca aacggtaggt agaaccatag cgtaaaacag taactgaaag cgggaaacca
    41101 tactcttcat ctccaaatat tttggagaat tcaaacagag gaaaatctgt ctgatagtcg
    41161 ctcaaactgt taacgccacc aaaaatacta taagacccaa cataccagtc ctggtcatcc
    41221 ttatattcat aaattttatt tgtcataatt ctacatgctc cacatgaatc tctttttcca
    41281 gccattcttc accaatttgt gcaaaacttt ggctactggc tgttgtgtaa aaacggtgat
    41341 ggagtggtcc agcatcgcga ccacgattga tttcaaaata attgagtaag actgagatat
    41401 cccgtacgca ctctgcccca ctatcgatga gctgaacctt tggccccatc acattttgga
    41461 taatagggcg aaggagtgga taatgagtac agcccaaaat caggctatcc acctttccaa
    41521 ccaagggacg cagggtttca tagaccacct tcttggtaac actggttgac agggcacctg
    41581 actcaaccaa gggagcaaac ttgggacagg ccaagctctc cacctgtaag tcgggatcca
    41641 gatcatggat tttctgacgg tatatgtctg attgtaccgt catgggcgtt ccaatcactc
    41701 cgattttccc accttgactg gacttgatgg ctgccgaagc tcctggcaaa attacaccca
    41761 agacaggaat atctagttga gccttgattt cttcccagac gaccgcagtc gcagtgttac
    41821 aagcaatgac aatcattttg acatccttgg tcaagagaaa gttgaccagc tgccaagtat
    41881 attcacgaat ttgctcagca ggacgggggc catagggcgc ccgcgccgaa tctccaatat
    41941 agacgatttc ttcatgggga agctggcgca tgagctcgcg cacaacggtc aagcccccga
    42001 cacccgaatc caaaaaacca attggtcgat tatccataca gtcttctttc tagtcttttt
    42061 tctgattgat cgttcattat gattccttgt actgaacgaa ctgaccgaca gcttgataga
    42121 atgtcaacta cctctctctt aatcataatc aaatatcaat agaatgcaag gaaaaagtct
    42181 catccctaaa ccataaccaa catagtgaga agtctggaac tttcatccca gacttttcct
    42241 tatttatttt ttctttttat tgttagcaag ggctgccttt tgttggcgga tgatttggtg
    42301 gtaaacttgt tgtaccttag cttcgcttgg tttttgacca tttgcactca aaagagtacg
    42361 aactgcttca gcattcaaac gtgggttgtc agcaaattct ttttcgattt gcttacgaac
    42421 caagtacatt cctccaagag ctcctcctag aaaagctagc acaatcaata caattgctaa
    42481 aagtaaatcc atcatttttc tcctgtttct ttttgaatcc ctttcattat accacaaact
    42541 agccaccctg accagtttgt tctacacttt cagggatgga atagacagca aaaagaaccc
    42601 tgcttttctg aaaaagaggt ctccttgcta agtttatact caatgaaaat caaagagcaa
    42661 actaggaagc tagccacagg ttgctcaaag caccgctttg aggttgcaga taaaactgac
    42721 acggtttgaa gagattttcg aagagtatta atttacataa atagccagtg tttgataggg
    42781 tttgagtaga attttctcag acacttctgc atcttcatag tttgatatca aaatctgtcc
    42841 attttggtag actgctggca agtcgatttc cacttcttta gcataaaagt tattgagcac
    42901 tagtaacttt tgatcctcaa actggcgttc aaaagcgtag acttgtttgc tatcttcaaa
    42961 ggctggtttg taacttcctt ctgaaatgat tggcatttcc ttacgcagtc gaatcaagtc
    43021 ttgatagaag gtgaaaatcg gaccctggat ttcattttct acattgatgt atttatagga
    43081 tttaccagct ttcaaccatg gagtgcctgt tgaaaatcct gcattttccg aagcatccca
    43141 ctgcatggga atgcgtgaat tatcacgcga cttagcttga ataatctgga aggcttcttg
    43201 ctgactcttt ccttcttcta agagcgtctg ataggcatta agcgattcga catccacata
    43261 atcagccata gaatcatagt ctgggtcaat catcccgatt tcttcaccca tatagatata
    43321 aggtgtccca cgtgacaggt gaatgctagc cgctagcatg gtggctcctt ccttgcggaa
    43381 gttttgaata tcgacaaaac ggttcaaggc acgtggttga tcgtgattgt tccaaaagag
    43441 ggcactccaa ccgtctttat cactcatttc cttaccccaa ctatggtaaa gactcttcaa
    43501 ctcttcaaaa tcaaagggag ccaaggtcca cttttgtcca tccttatagt ccaccttgag
    43561 gtgatgaaaa ttaaaggtca tggataattc ctgacgatca ggcgacgaat agaggacaca
    43621 gttttccatg gtggtagaag acatttcccc aactgtcata aagctatcgt cagatccaaa
    43681 agtggcttgg ttcatcatac gcaaatagtt atgaacgatg ggtttgtctg tataagctgg
    43741 cttcccttca ttttcaggac agtccactga aacctcgtcc ttaccgatca aattgatcac
    43801 atcaaatcgg aaacctttga tacccttgtc gcgccagaaa ttaacaacct tgaaaagctc
    43861 cttacggaca ttggaattgc gccagttaag gtcagcctgg gtctcatcaa ataggtgaag
    43921 atagtatttc ccagtatccc cgaaaggcgt ccatgcagaa ccaccaaact tagactgcca
    43981 atctgttggt tggtcttgga tgaagaaaaa gtcttgataa tacttatcac cagctagggc
    44041 tttctgaaac cattcatgct ctgtcgaaca atgattaagt accatgtcca gcataaagtc
    44101 aatcttgtgc tctttaccga cacacaccat ttcctcaaaa tcagccatat caccaaaaag
    44161 aggatccact gccatataat ctgaaatatc gtaaccatta tcccgttgag ggcttggata
    44221 gaatggattg agccagacca tatccacacc tagtttggct aaatagggaa ttttttcgat
    44281 aatcccacgg aaatccccaa taccgttttc agtggtgtct ttgtaagatt ttggatagat
    44341 ttgatagact acttttcctt tatcaagtgt catctgtttc tccttttctg ataaaaggga
    44401 ggaagcagtc ttccgtccct atttgtgcta tttcaattat actcaatgaa aatcaaagaa
    44461 caaactagga agctagccac aggttgctca aaacactatt ttgaggttgc agatagagct
    44521 gacgtggttt gaagagattt tcgaagagta ttagattcgt gtagcgacca tgagagatgc
    44581 tccagcttgg atcgttgtcg gataagttcc gggaatagtc gctgtataag catcttggtt
    44641 ggtgatgata acaggagttt ctgtcaccag acctgcagcc ttaatgacat ccatatcaaa
    44701 acgaatcagt tgctgaccaa ctgtaacgtg atctccttgg actacaagac tttcaaaacc
    44761 tttgccatca agacctactg tatccatacc gatgtggatg agcaattcaa ctccctcgtc
    44821 agagacaatg ccgatggcat gcttggtagg gaaaagaacc gtcactgtcc cattaactgg
    44881 agaggtcaac tcaccttggc ttggttcaat gactagacct tgccccatga cacctgatgc
    44941 aaaaatagga tccgtcgctt gactcaattc tttcacttgg ccagttagtg ggctgataat
    45001 ttctaccgaa gtaagttcta ctggttcatg gttcacaaat tctgcttctt cttgagcaac
    45061 gaattctgcc tgcaagttcg tatcgccctc tgtttttgta aagagaccag ccttgcggaa
    45121 gaagaaagtc aagagcattg gaacaacaat cgcaactagc atagttcctg caaatggcag
    45181 catgtattga ggttgaatag agagaatacc tggcaaacca ccgataccaa tagaagccgc
    45241 agttacatta aaagtaacgg ataacatgcc tgcaagggct gaaccagtca tcccagcaac
    45301 aaatggataa atatatttta cgttaacccc aaaaagagct ggttctgtaa caccgagata
    45361 ggctgaaatg gttgcaggaa gtgaaacctg agcctcacgc tcatcatggc gatgcatgaa
    45421 ataatagaca aacacggctg agccttgagc aatattagaa agagcaatca ttggccatag
    45481 ggcagtgcca ccagcatccg caatcaattg tgtatcaatg gcattggtca tatggtgcag
    45541 acctgtgatg acaaatggag cgtagagggc accaaaaatt gcaccgaaga gccatttaac
    45601 tggaccagtt aaacctgcca agacaactga tgaaagtcct tgtccaattg tccaaccgat
    45661 tggtcccaaa acagtatgag ccaaaatcaa ggctggaatc aatgacaaga aaggtacaaa
    45721 aatcatagaa atgacttctg ggatatgctt gcgccagaag atttcaagat aagacagact
    45781 caaacctgca agcaaggctg ggataacttg ggcttggtaa ccgatacgat taacagtaaa
    45841 atagccaaaa ttccaaaccc agtttgccgc gatatcagct gctggcgttg aagcaaccgc
    45901 ataggcattg agcaactgag gcgataccaa acagattccg agaacaattc ccaaaatttg
    45961 gctggttccc atcttacgag aaacagacca agtaatccct actggtaaga actggaagat
    46021 agcttcacca ggcaaccaga ggaagtgatt gacacctgcc caaaactgag aggattctgt
    46081 gatggtcttg ccatccaaca tcgaccaatg gacaccttcc aagacattac ggaaaccgag
    46141 gatcaatcct ccgactatca aggctggaat aatcggagta aaaatctccg ccagagtggt
    46201 cataacacgt tggaccacgt tttgattact cttagctgca gacttggctg cttctttgga
    46261 aacaccctca atacctgaaa cggctgtaaa atcattataa aagatgggca cgtcatttcc
    46321 aatgattacc tgaaattgac ctgcatttgt aaaagttcct ttaacagctg gaattgactc
    46381 gatagcttta acattagcct tcttatcatc tcctaaaaca aagcgcatcc gtgtcgcaca
    46441 gtgggtgacg gcagtcacat tttctttgcc tccaattgcc tgaagcagat ctttggcttc
    46501 ttgttcaaat tttcccattt gattctcctt atacttgtca aagcaagttt gatttgataa
    46561 gtatattgta aacgatacca aacttgtctg caacttgttt ggtataaaaa gggtgttttt
    46621 ttgtaaattt tctagcactt gtatggtaaa atagatacag gtgttcatta aactagacta
    46681 aaaacctatt taagcaggca aaatgaagaa ataccaacaa ttatttaagc aaatccaaga
    46741 aaccattcaa aacgagactt acgctgtcgg agatttcctt cctagcgagc acgaccttat
    46801 ggagcaatat caagtgagtc gtgataccgt ccgaaaggcc ctgtctctcc tccaagagga
    46861 aggattgatc aaaaagataa gagggcaagg ttctcaagtc gtcaaagaag aaaccgtcaa
    46921 tttccctgta tccaacctaa ccagctacca agaactagtt aaagaacttg gactgcgctc
    46981 taaaaccaac gtggtcagtc tggacaagat tattattgat aaaaaatcct cactgataac
    47041 cggtttccca gagtttcgga tggtttggaa ggtggtccgc cagcgtgtgg tggatgatct
    47101 ggtatccgtt ctggatacag actatctgga tatggaacta attccaaatc tcactcgcca
    47161 aattgctgag cagtctatct attcttatat agaaaatggc ctcaaactcc ttattgatta
    47221 tgctcagaag gaaatcacca ttgaccactc aagcgaccga gacaagattc tcatggacat
    47281 tggcaaagac ccttatgtcg tttcgattaa atcaaaagtc tatctccaag acggacgcca
    47341 atttcagttt accgaaagtc gccataagtt agaaaaattt agatttgtag attttgcaaa
    47401 acgcaagaaa taaaagactg agacaccaga tctcagcctt tttcggctct ataatatttg
    47461 tagtgggtaa cccccctatg gatattatgg agcctatttt gtgtagaaaa aaagtcccat
    47521 atgacctata atgaaaagcg acaaaacaac tcattagaaa gaatcatatg gaacaattac
    47581 attttatcac aaaattacta gacattaaag accctaatat ccagatttta gacatcatca
    47641 agaaggatac acacaaggaa atcatcgcca aactggacta tgaagctcca tcttgtcctg
    47701 agtgcggaag tcaaatgaag aaatattact ttcaaaaacc ttctaaaatt ccttatcttg
    47761 aaacaactgg tatgcctact agaattctcc ttagaaagcg tcgtttcaag tgctatcatt
    47821 gttctaaaat tatggttgct gaaacttcta tcgtcaagaa gaatcaccaa atccctcgta
    47881 tcatcaacca aaagattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc
    47941 atcagctttc catctcaact tcaactgtca ttcgaaagct caatgacttc cactttgag
//
LOCUS       DAVKUR010000010        47461 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKUR010000010 DAVKUR010000000
VERSION     DAVKUR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.010"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            47..394
                     /locus_tag="VW749_000649"
     CDS             47..394
                     /locus_tag="VW749_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0174733.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(511..1644)
                     /locus_tag="VW749_000650"
                     /pseudo
     CDS             complement(511..1644)
                     /locus_tag="VW749_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1709..1990
                     /locus_tag="VW749_000651"
     CDS             1709..1990
                     /locus_tag="VW749_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0174734.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2122..3066
                     /gene="manA"
                     /locus_tag="VW749_000652"
     CDS             2122..3066
                     /gene="manA"
                     /locus_tag="VW749_000652"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0174735.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(3106..4441)
                     /locus_tag="VW749_000653"
                     /pseudo
     CDS             complement(3106..4441)
                     /locus_tag="VW749_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            4669..5418
                     /locus_tag="VW749_000654"
     CDS             4669..5418
                     /locus_tag="VW749_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0174736.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(5438..5893)
                     /locus_tag="VW749_000655"
     CDS             complement(5438..5893)
                     /locus_tag="VW749_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0174737.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(5913..7088)
                     /locus_tag="VW749_000656"
     CDS             complement(5913..7088)
                     /locus_tag="VW749_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0174738.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(7147..7992)
                     /locus_tag="VW749_000657"
     CDS             complement(7147..7992)
                     /locus_tag="VW749_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0174739.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            8117..8674
                     /locus_tag="VW749_000658"
     CDS             8117..8674
                     /locus_tag="VW749_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0174740.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            8693..9160
                     /locus_tag="VW749_000659"
     CDS             8693..9160
                     /locus_tag="VW749_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0174741.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            9249..9878
                     /gene="upp"
                     /locus_tag="VW749_000660"
     CDS             9249..9878
                     /gene="upp"
                     /locus_tag="VW749_000660"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0174742.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            10052..10642
                     /gene="clpP"
                     /locus_tag="VW749_000661"
     CDS             10052..10642
                     /gene="clpP"
                     /locus_tag="VW749_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0174743.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            10721..10969
                     /locus_tag="VW749_000662"
     CDS             10721..10969
                     /locus_tag="VW749_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0174744.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            11070..12230
                     /locus_tag="VW749_000663"
     CDS             11070..12230
                     /locus_tag="VW749_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0174745.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            12498..13367
                     /locus_tag="VW749_000664"
     CDS             12498..13367
                     /locus_tag="VW749_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0174746.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            13371..14327
                     /locus_tag="VW749_000665"
     CDS             13371..14327
                     /locus_tag="VW749_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0174747.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            14327..15091
                     /locus_tag="VW749_000666"
     CDS             14327..15091
                     /locus_tag="VW749_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174748.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            15091..15801
                     /locus_tag="VW749_000667"
     CDS             15091..15801
                     /locus_tag="VW749_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174749.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            16160..16816
                     /locus_tag="VW749_000668"
     CDS             16160..16816
                     /locus_tag="VW749_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0174750.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            16924..18019
                     /gene="prfB"
                     /locus_tag="VW749_000669"
     CDS             join(16924..16995,16997..18019)
                     /gene="prfB"
                     /locus_tag="VW749_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0174751.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            18037..18729
                     /gene="ftsE"
                     /locus_tag="VW749_000670"
     CDS             18037..18729
                     /gene="ftsE"
                     /locus_tag="VW749_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0174752.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            18722..19648
                     /locus_tag="VW749_000671"
     CDS             18722..19648
                     /locus_tag="VW749_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174753.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYYKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            19934..22114
                     /locus_tag="VW749_000672"
     CDS             19934..22114
                     /locus_tag="VW749_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0174754.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            22166..22981
                     /locus_tag="VW749_000673"
     CDS             22166..22981
                     /locus_tag="VW749_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0174755.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTESLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            23121..24464
                     /locus_tag="VW749_000674"
     CDS             23121..24464
                     /locus_tag="VW749_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0174756.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDRNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            24841..26031
                     /locus_tag="VW749_000675"
     CDS             24841..26031
                     /locus_tag="VW749_000675"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0174757.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            26584..27519
                     /locus_tag="VW749_000676"
     CDS             26584..27519
                     /locus_tag="VW749_000676"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0174758.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            27553..28590
                     /locus_tag="VW749_000677"
     CDS             27553..28590
                     /locus_tag="VW749_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0174759.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            28763..29368
                     /locus_tag="VW749_000678"
     CDS             28763..29368
                     /locus_tag="VW749_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0174760.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            29525..30055
                     /locus_tag="VW749_000679"
     CDS             29525..30055
                     /locus_tag="VW749_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0174761.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            30076..31161
                     /gene="rlmN"
                     /locus_tag="VW749_000680"
     CDS             30076..31161
                     /gene="rlmN"
                     /locus_tag="VW749_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0174762.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            31161..31643
                     /locus_tag="VW749_000681"
     CDS             31161..31643
                     /locus_tag="VW749_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0174763.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            31645..33186
                     /locus_tag="VW749_000682"
     CDS             31645..33186
                     /locus_tag="VW749_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0174764.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(33242..34045)
                     /locus_tag="VW749_000683"
     CDS             complement(33242..34045)
                     /locus_tag="VW749_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0174765.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34128..34349)
                     /locus_tag="VW749_000684"
     CDS             complement(34128..34349)
                     /locus_tag="VW749_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174766.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(34828..35025)
                     /locus_tag="VW749_000685"
     CDS             complement(34828..35025)
                     /locus_tag="VW749_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174767.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            35195..35467
                     /gene="rpsP"
                     /locus_tag="VW749_000686"
     CDS             35195..35467
                     /gene="rpsP"
                     /locus_tag="VW749_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0174768.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35487..35726
                     /locus_tag="VW749_000687"
     CDS             35487..35726
                     /locus_tag="VW749_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0174769.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            36303..37091
                     /locus_tag="VW749_000688"
     CDS             36303..37091
                     /locus_tag="VW749_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0174770.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            37122..37640
                     /gene="rimM"
                     /locus_tag="VW749_000689"
     CDS             37122..37640
                     /gene="rimM"
                     /locus_tag="VW749_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0174771.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            37630..38349
                     /gene="trmD"
                     /locus_tag="VW749_000690"
     CDS             37630..38349
                     /gene="trmD"
                     /locus_tag="VW749_000690"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0174772.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            38361..38699
                     /locus_tag="VW749_000691"
     CDS             38361..38699
                     /locus_tag="VW749_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174773.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(38730..39050)
                     /locus_tag="VW749_000692"
     CDS             complement(38730..39050)
                     /locus_tag="VW749_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174774.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            39148..39363
                     /locus_tag="VW749_000693"
     CDS             39148..39363
                     /locus_tag="VW749_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0174775.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(39522..39608)
                     /locus_tag="VW749_000694"
                     /pseudo
     CDS             complement(39522..39608)
                     /locus_tag="VW749_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(39659..40195)
                     /locus_tag="VW749_000695"
     CDS             complement(39659..40195)
                     /locus_tag="VW749_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0174776.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(40392..41738)
                     /gene="gor"
                     /locus_tag="VW749_000696"
     CDS             complement(40392..41738)
                     /gene="gor"
                     /locus_tag="VW749_000696"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0174777.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            42024..43223
                     /locus_tag="VW749_000697"
     CDS             42024..43223
                     /locus_tag="VW749_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0174778.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            43207..43908
                     /locus_tag="VW749_000698"
     CDS             43207..43908
                     /locus_tag="VW749_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174779.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            43910..45169
                     /locus_tag="VW749_000699"
     CDS             43910..45169
                     /locus_tag="VW749_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174780.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            45293..47290
                     /gene="metG"
                     /locus_tag="VW749_000700"
     CDS             45293..47290
                     /gene="metG"
                     /locus_tag="VW749_000700"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0174781.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        14506 a         8804 c        10289 g        13862 t
ORIGIN      
        1 actttaaaag atcggagcaa tccggtcttt ttatggagga gagtaaatga atttaaatca
       61 attagatatt atcgtttcaa atgttcccca agtctgtgct gacttggagc atatcttgga
      121 taaaaaggca gattatgctg atgatggttt tgctcagttt acgattggta gtcactgcct
      181 tatgttgtca caaaatcatt tggttccttt ggaaaacttt cagtcaggaa tcattattca
      241 tatcgagatt gaggatgtag accagaacta caaacggttg aacgagcttg gtataaaggt
      301 tttacacgga ccaactgtaa ccgattgggg aacagagtcc ttattagttc aaggacctgc
      361 tggtctagtg cttgattttt atcgtatgaa ataggtcgcg tagtcatttg acgttaacct
      421 tagctatttt taaaatagaa attgagaata tgaactattg aaagatcgga gcaatccggt
      481 ctttttatat aaagaaattg catataatac tcatctgctt tcaaaaagca ttctagtcca
      541 tctccgatta acgatggact ttatcacctc cttctccaat ccttgtatga catcttggag
      601 ttgattcatg acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat
      661 ctctttccac acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaatgcaaa
      721 gccaatatta gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac
      781 gagtaaaaaa taatcatatg gataagcttg tgaaagctct tctaaaaaga cgttcatcca
      841 ctcagtatta catccaccag ctcttaagaa aaatgattcg cctgtatagg catcaacagc
      901 tccataacaa tagcgaaatt ctcgtatata gtgactatgg atatgtggac ctactcctat
      961 tggagaccaa caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat
     1021 caagcgaacc ttacgaaaac gtctactggt tttaaatcgc tttcttttct tcttgaattg
     1081 agattttatt tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac
     1141 gtggcgtaat atttcgccaa ccatggcgct tcaacagttg atagaaggca tcacgtgtgt
     1201 aggaacgacc taactccttt ttataagcct gaaataaggc atcaattgta acaaattctc
     1261 ctgcctctgt agccttcaaa tgacgggcaa gaaaggcttt ctcttcctca actgtcatat
     1321 atgcatggtt acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat
     1381 attttttaca ttttgctaaa tcgttgtttg attacagtct aaaagctcta taatctcttt
     1441 ataagatttg cccatcagac gaaatataat agattgaaac tagaatagta cacctctact
     1501 tctaaaacat tgttagaaat cgatttgtcc tgttcttgtt tcattttact atagaacgat
     1561 ttgaaggcgt ttataatatt tagctgtacg agagtctttt aaaagtgttt tgatggtttg
     1621 gatttcttct ttagttgatt tcatattact attgtataat gctttttgat tttagtttag
     1681 tattatcgta gaaaatggac tcggtgctat ggatacaccg gatgagaatg gttatgtagc
     1741 agatgactat cggattactt acttagaggc ccacatcaag gccatgcgag atgccattta
     1801 ccaagatggg gttgacttgc ttggttatac gacttggagc tgtatcgatc cggtttcagc
     1861 tggcacaggg gaaatgaata agcgctatgg ctttatctat gtagatcgag ataatgtagg
     1921 aaatgggact ctcaaacgta gcaagaagaa gtccttctat tggtacatgt catttatagc
     1981 aatggtgtaa gcatcgagta gagcacattt gtttactatt tttataaaat cttctccctg
     2041 ctttataaga tgtaaaaaag agttcaaatg gaactctttt tttgctataa tgaggggaga
     2101 aaaatcagac aggagattaa gatgtcagaa ccattatttt tacaatcagt tatgcaagaa
     2161 aaaatctggg gtggtaccaa gttacgtgat gagtttggct acgacatccc aagtgaaaaa
     2221 gtcggagagt actgggctat ctcagctcat ctaaatggtg tttctaaagt tgccaatggt
     2281 cgttacgagg gaacagatct tgctactttg tatgcggaac accgtgaatt atttggcaat
     2341 cgtccagaac ctgtatttcc gcttttgacc aagatcctcg atgccaacga ctggctcagt
     2401 gtccaagttc acccagacga tgcttatgga ctcgagcatg aaggcgaact tggaaaaaca
     2461 gaatgttggt acatcattgc agcagatgaa ggttcagaga ttatctacgg tcacaatgcc
     2521 aagtcaaaag aagaactccg ccagcaaatc gaggataaga actgggatgc gctgttgaca
     2581 aaagtgccag ttaaagcagg agatttcttc tatgtaccaa gcggtaccat gcacgctatc
     2641 ggggcgggta tcttgattct tgaaacccag cagtctagcg ataccactta ccgtgtctat
     2701 gactttgacc gtaaggatga caagggcaat ttacgtgaac ttcaccttga aaaatctatc
     2761 gatgtcttga acattggtga acccgcaaat agccgtccag tgacaatcaa agcagatgat
     2821 ctacgttcca ctctccttgt atccaatgat ttcttcgcag tttacaaatg ggaaattact
     2881 ggaaaagtta actttgaaaa gacagctgac tacagcttgt tgagtgtctt ggctggtcaa
     2941 ggtcagctaa ctgttgacgg gaaaaattat ccaattcaaa aaggcagcca ctttatccta
     3001 ccaagtgatg ttgaagcttg gactctggaa gggcaaggtt tggaattgat tgttagccat
     3061 ccataaaaag aaagggcctg agttcactac tcaagtcctt tttgattaca taaattgggc
     3121 aatgaagacc acaatgatga tgattggaat gacgaaacga agaaacgaag aaggaagagc
     3181 cagacttgga acagtccttg tttccatgct ctttcatcga gatggagttc ctccattgca
     3241 agagcctttt taaagatata gcctgtaaaa agtgaaaggt agagagctcc aaatggcatg
     3301 aggagattgg aaaccaagaa gtccatagcg tcaaagaagg tcttaccaaa aatgtgaaca
     3361 tccgccatga caccgtaaga tagggctgaa ggaatgccaa agacaaaggt caaaattcct
     3421 aaaataacac tccatttggc acgtttgctg ttatcctggt tggtgatatt gcccacattg
     3481 atctccagca tcacgacaga agaagtgaca gtcgcaaaga gggagcggac gtagaaaatg
     3541 gttccaaaag gcatcttgtc aaagagttga ggcaagacga taaagagcag gctgggtccc
     3601 ccttcagact ggatattgaa gggggatcga gcttggaaaa tggctagacc tgccatgatg
     3661 gatatcgaga tattcatggc tacgatggag attcctgact ggactagatt ggttttcttg
     3721 tccaagtaag aagcataggt caacatgact gtaaccccta gtgagagggc aaagaaagat
     3781 tgtcccagag catagaggag accagcgcta gtcagttttg aaaagtctgg tttgaggaag
     3841 taaagaaccc cttccatggc atttggcaaa ctgagagagc gactgatgat aaaaacaaag
     3901 acgataaaga gcaggggcat catgactttc gaagctcttt caatcccttt ttgaacccca
     3961 cgtgatacaa tgaagatatt caataggata aaggccgctt gagctcctag ggcaatggct
     4021 ggatttgaaa tgattgaagt aaataactga gcataatcac ccgttccacc aagttggaac
     4081 aatttcccaa actcaatacc tagatagact agaatccatc ctccgataac actgtaaaaa
     4141 gataagagga taaagagggc aaaggcgcca atccaaccga taaagttgta cttgttattc
     4201 ttgcccagtt ttccaaaggt tttgatagcg gaaacgccag cactacggcc aagggcaaac
     4261 tcagccagca ggagagggaa accgattaaa atagtggaaa tgagaaagat tagtaaaaag
     4321 cctccaccgc cattagcagc agtcatgtag ggaaacttcc aaacggaacc aagcccgatg
     4381 gccagccagc agatgctaga ataaaaccaa gtttcgaccc ccattgtgat ttttctgaca
     4441 tagttaaact ctgatctcct ttttcaaaat aagaaaaagc tacttgagtt gtcaaatagc
     4501 cttctgtttg attgatagac ttgactatcc tatcatgttt tctaaggtct gtcaagaaaa
     4561 tcattttcaa gttttcacac ctttctcaaa aaagttaaaa aattttctca aaaacgcttg
     4621 actctgacct aaggggaggg gttatactat cattgtaagg aggaaatcat gtaccatata
     4681 aaagaagctg cgcagctttc aggtgtctct gtcaagaccc tgcatcacta tgacaagata
     4741 ggactcttgg tccccttaaa gtcggaaaac ggctatcgaa cctacagtca agaggatttg
     4801 gaacgccttc aggtcattct ttactacaaa tatctaggct tttctttaga gaaaatagca
     4861 gagctgttaa aggaagaaag gacagattta ttgccccatt tgactaggca gttggactat
     4921 ctaactcgcg aaaggcaaca tctggatacc ttgatttcca ccttgcaaaa aactattcaa
     4981 gaacaaaaag gagaaagaaa aatgaccatt gaggaaaaat tcacgggatt tagctatcaa
     5041 gacaatcaaa aataccacca agaagcggta gagaaatatg gtcaagaagt catgggacaa
     5101 gcgctcgaac gccaaaaagg tcacgaagac gaggctacgg ccgcctttaa ccaagtcttt
     5161 caaactttgg cacaaaatct tcaagttggt ttacctgcaa cagcaaccga aaaccaggag
     5221 caagcagcca agctcttgca agccattcgc acttatggat ttgactgctc tattgaggta
     5281 ttcggtcata tcggtaaagg ttacgtctat aacccagagt ttaaggaaaa cattgacaag
     5341 tttggttctg gaacagccca gtacacgtca gatgccattg cagcttacgt tcagacaaat
     5401 gcagaaaaaa taggctagga atttcctagc ctatttttta cttcaaatca taaagccagt
     5461 cgtcaccgtt tttgtagtaa aagaattcac tgagatcttc ttctagaaac acacgaagca
     5521 tatcagacat atcatcggtt gcaagtttta gatgagaaag attttcaaag tcctcccacc
     5581 aaactttccc ttcgtctgaa gactggagtt caccagtaaa gtgttctgtc ttgtaaaaaa
     5641 ggacgacata acgataatcc ttgtcgtcat accagttttt gataccacag agttggggtt
     5701 tggaaatgat cagaccagtt tcttctttca cttcacgaat gacagcatcg acaaaggatt
     5761 cgccacgttc aacatgacca ccaggaaaag taatgccagg ccagtcggga ctaactcggt
     5821 cttggaccag gaccttatct ccgtttttaa tcatacacat gttaacaaat tcgactgcct
     5881 ctcttctgtt cattcttcac aacctttaat ctttaatcat aatgcagact tcccgccacc
     5941 cagccggtac agagggcaga agtgatgtta aagccacccg tgtgggcatt gatatccata
     6001 acttcgcctg caaagtggag gccaggtacc agcttacttt caagggtttt aggattgatt
     6061 tccttgagac tgactccacc cttggtaaca aaggactttg caagggacat ttttccagtt
     6121 acaggaattt taagttcttt aatggactga acaagttgtt ctcgttcctt ttcagtcagc
     6181 tgtttgactt tttcaggata tccttgtaca aaaaattcgg ccaagcgttc tggtaacaag
     6241 gtttttaaag cgtttttcaa ggatttttcc cgattttctt ctagaaatgt aaccaagtcc
     6301 ttctcagaaa gttgaggcaa aacatcgagt gagagaacct ccccaccttt gacaaagcta
     6361 gacatgcgta gggcagcagg acctgacaaa ccaaagtggg taaagagtaa atcatgagtg
     6421 atgacatgct taccataact tagggtcaca tcgtccagag aaatcccttg taaggcttta
     6481 tgtggaaaat ctgttaataa aggactttca gcagcctcaa gctcggtgat ggtatgctta
     6541 aaatggcgag caatctcgtg accaaaacca gtcgaaccag tcgaaggata agacttacca
     6601 cctgttgtga caatgagttt ctcacaagtg aaggtttgat ccgctgactt aaggacaaac
     6661 tggtcatcta cttttttaac agaaacgatt tctatttgag tagcaacttg accacctagt
     6721 tcggtgattt tcttttccaa agcttcgata atagtccgag acttgtcact ggctggaaag
     6781 acgcgtccgt ggtcttcgac cttaagttta acaccatttt ctgtaaaaaa gttgatgatg
     6841 tcatgattat cgaactggga gaaaacactg taaagaaagc gtccgtttcc aggaattcca
     6901 gctagcaggt tgtctaagct accattgttg gtcacattgc aacgtccccc accagtccca
     6961 gctaattttt ttccaagttt ccgatttttt tcgatgagga gggttttctg tccataaaag
     7021 ctactggaaa tcgtagccat cataccagca ggtcccccac cgatgacaat agtatcaaaa
     7081 tgtttcatag ctctattgta ccacaaaaaa acaagagatg atggtcacct cttgtcaaga
     7141 atgcaattaa tcaatttcat agcccatcag caaaccgcca tcttctgcat agaaactgca
     7201 gagaccagag gttggtagaa ttttaatatc cgcttgtggg aaggtttcac ggattcgctc
     7261 tgagagctgt tgacaacatt tttcgttatt gcgttgggcc atgacaatac ggccaccagc
     7321 atatccagct tttactaact catcataggc agcttgaact gatttctttg atccccttgc
     7381 tttttgtagc aattcgagag tcccagtttc actagctttt ccgaccatac gaatgttgag
     7441 aaggccaacg accgtaccga taagcttgct caaacggccg ttcttcacca agttatcgac
     7501 tttggctagg acaaagagca acttagtttt ttcttgatag gcggtgatag cttcaaccac
     7561 ttcttcaaaa gacaagccct ggtcaatcaa gtcattcaat ttttctacga gtaggtcaac
     7621 ttcaccacca gcagataaac tatcaatcac atgaatctta gtgtcaggat ggtcttccag
     7681 ataaatattc tttgctagtt gagcactatt gtgactgcca gaaagggtac ctgtgatggt
     7741 tactaggaaa atgtttttgg caccttcaaa tgctcgcaaa tagtcatctg ggcttggaca
     7801 agccgatttt gaagcttctg cagttgcata catggtttcc atcatttggt caatatcgag
     7861 actggcgtca tcaacaaaga cctgatcagc tacttgaatg gttaagggga cacttacaaa
     7921 ggttgtgtta atagctggtg ttggcagttg acgataatca caaccagagt cagcaataat
     7981 tttccaagtc atagaaattc tccatctttg tcagttatac attgacaaag gttctgtctt
     8041 tttttacaat tatatcatga aaacccttga aacaaaagca tcatccgtct gttgtgacaa
     8101 gtagaaagaa aatgttatgt ctgaacgtag aatctctgaa aagtctcttg aaaatctcag
     8161 aaaatcaaac caagaatcca atttattaac cagagaagcc attgaaacag ccctcttgca
     8221 actcttggaa aaaaaggagc tgaccaagat tagtatttct gaattggtca aacgtgcagg
     8281 tgtttcgcgt gcggcctttt atcgcaatta tgactccaaa gaggaaattt tagagagcgt
     8341 ctttaaacga actgtccaca atattatgga acagctgcat cattacgatt taaagacaga
     8401 cctttatttg gtttgggttc accttttccg ggaggccaga aaggaagcta gagtgattca
     8461 attggccttg gattaccatc tggaaaaaat ctttgtccaa gccatgcagg aatttctaga
     8521 aaaataccat gggaaatcaa aaggtgtcag ctcttatctt cattccttct ggagctcagc
     8581 catcgtctct gtccttctaa aatggatcaa ggatggcatg aaggtaccag ctgaaaagat
     8641 tgcagattta ggtttaccat tttttaaaaa atagagaaaa aggagaaaag agatgactga
     8701 aaaaagactg gcctgggatg agtattttgc agcccaagcc ctactaattg cgaatcgttc
     8761 cacttgtaaa cgtgctaaag tgggcgcgat tctggtaaaa gataataagg ttatttccac
     8821 tggttacaat ggttcggtgt cagggactga gcattgtatt gatcacgaat gtttggtcat
     8881 tgaaggccac tgtgttcgca cccttcacgc tgaggtcaat gctatccttc aaggtgctga
     8941 gcgtggtgtt cccaaaggct ttacagccta tgtaacccat tttccttgtc tcaactgtac
     9001 aaaacaattg cttcaggtcg gctgcaagcg cgtggtttat atcaaccagt accgaatgga
     9061 cgactacgcc caataccttt atcaagaaaa agggacagaa ttgacccatt taccacttga
     9121 gacagtacag acagctctta aagaggctga tctaatgtaa aaattatcaa aaataaatgg
     9181 cttagaaaga tttttaaacc gttttttggt ataataagaa gaataaattg aaagaaggaa
     9241 ttccaaaaat gggaaaaatt gaagttatta atcacccact gattcaacac aaattgtcaa
     9301 tcttgcgtcg tacagatact tctacaaaag cttttcgtga gctagtagat gagattgcaa
     9361 tgttgatggg gtatgaagta cttcgtgatc ttccactaga agatgtggaa atcgaaacac
     9421 caattacaaa aacagttcaa aaacaattgg caggtaagaa attggccatc gtcccaatct
     9481 tgcgtgcagg tatcgggatg gttgatggtc tcttgagctt ggttccagct gctaaagttg
     9541 gccacatcgg tatgtaccgt gatgaagaaa cacttcaacc agttgaatac ttggtgaaat
     9601 tgcctgagga cattgaccaa cgtcaaattt ttatagtaga cccaatgttg gcaacaggtg
     9661 gctcagcaat cttggctgtt gattctctta aaaaacgtgg cgcatcaaat atcaaatttg
     9721 tctgccttgt atctgctcca gagggtgtaa aagcccttca agaagctcat ccagatgtag
     9781 aaatctttac agcagccttg gatgaacgtt tgaacgaaca cggttatatc gttccaggtc
     9841 ttggagatgc tggagaccgc ttgttcggta caaaataaga tcgaaaagaa gaatgacttg
     9901 gaaaagtatt tccagtcacg aaaggaggtt gggtttttgt ttctgtctaa tgaaagcaga
     9961 gcaaaaattt gacctttttt gaccaagata ttataatagt cttatcttca gtcagttgac
    10021 caacaaaatt aaaactcaaa aggagaaatg aatgattcct gtagttattg aacaaacaag
    10081 ccgtggagaa cgttcttacg atatttactc acgtcttctc aaagaccgca tcattatgct
    10141 gacaggtccg gttgaagaca atatggctaa ctctgttatt gcccaattgc ttttcttgga
    10201 tgcccaagat agtacaaaag atatttacct ttatgtcaat acaccaggtg gttctgtttc
    10261 agctggtttg gcaatcgtag ataccatgaa ctttatcaag gcagatgtcc aaaccatcgt
    10321 tatgggaatg gctgcatcta tgggaacagt catcgcatca agtggagcaa aaggcaaacg
    10381 tttcatgctt ccaaatgctg aatacatgat tcaccaacca atgggcggta caggtggtgg
    10441 tacccaacaa actgatatgg ctatcgctgc agaacacttg ctcaaaactc gtaatacctt
    10501 ggaaaaaatc ttggctgaaa attcaggtca gtcaatggaa aaagtccatg cagatgcaga
    10561 acgtgataac tggatgagcg cccaggaaac acttgaatat ggctttattg atgaaattat
    10621 ggccaacaat tcattgaact aatgatgata gaaggcaaac tcgactgggt ttgctttttt
    10681 tggtataata gggagagatt tcttagaaag aggatttatc atgtttgaaa aagtcaatcg
    10741 ctctggcttg attatctatc tttactataa tcgtgatgcc aaaaaattgc aggattatgg
    10801 agatattacc tatcattcca agaaacatcg ttacttacaa ctctatgttc caactcaaga
    10861 agtggagcaa ttggtcggac gcttgagcaa ggaaaaattt attaaaaaag ttagggtttg
    10921 tcatatccaa gagttggaaa caccctttgt gggcaatctt tatcgatagg aaaacgttat
    10981 catagaaaaa gttcaaggaa aacattgaca attttctgat aattcggtat attcttaaca
    11041 gactatttaa gaaataagga gacaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg
    11101 cgcttgcaag tgtagcactt cttgcagcct gtggagaagt gaagtctgga gcagtcaaca
    11161 ctgctggtaa ctcagtagag gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag
    11221 gttctttagc tgcatacgga acagctgaac aaaaaggtgc ccaattggct gttgatgaaa
    11281 tcaatgccgc aggtggtatc gatggaaaac aaatcgaagt aatcgataaa gataataagt
    11341 ctgaaacagc tgaggctgct tcagttacaa ctaaccttgt aacccaatct aaagtatcag
    11401 cagtcgtagg acctgcgaca tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag
    11461 caggtgttcc attgatctca ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt
    11521 acctctttat tggaactttc caagatagct tccaaggaaa aattatctca aactatgttt
    11581 ctgaaaaatt aaatgctaag aaagttgttc tttacactga caatgccagt gactatgcta
    11641 aagggattgc caaatctttc cgcgagtcat acaagggtga aatcgttgca gatgaaactt
    11701 tcgtagcagg tgacacagac ttccaagcag cccttacaaa aatgaaaggg agagactttg
    11761 atgctatcgt tgttcctggt tactataatg aggctggtaa gattgtaaac caagcgcgtg
    11821 gcatgggaat tgacaaacca atcgttggtg gtgatggatt caacggtgag gagtttgtac
    11881 aacaagcaac tgctgaaaaa gcatcaaaca tctactttat ctcaggcttc tcaactactg
    11941 tagaagtttc agctaaagct aaagccttcc ttgacgctta ccgtgctaag tacaatgaag
    12001 agccttcaac atttgcagcc ttggcttatg attcagttca ccttgtagca aacgcagcaa
    12061 aaggtgctaa aaattcaggt gaaatcaaga ataaccttgc taaaacaaaa gattttgaag
    12121 gtgtaactgg tcaaacaagc ttcgatgcag accacaacac agtcaaaact gcttacatga
    12181 tgaccatgaa caatggtaaa gttgaagcag cagaagttgt aaaaccataa tagaaaaatg
    12241 ttgaaatagg gaatgagcct ttgactcact ccctgtttcg atatttaata ctcttcgaaa
    12301 atctcttcaa actgcgtcaa cgtcgccttg gattatatat gtgactgact tcgtcagtct
    12361 tatctacaac ctcaaagcag tgctttgagc aacctgcggc tagtttccta gtttgctctt
    12421 tgattttcat tgagtataag aacctatcaa aaagtgaggg aaaaccctcg gaattataaa
    12481 tagaaagagt gaatcttatg ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt
    12541 acgcgctgtt agccctagga tataccatgg tttacggaat tatcaagctc atcaacttcg
    12601 cccatggtga tatttatatg atgggagcct ttatcggtta tttcttgatc aattctttcc
    12661 aaatgaattt ctttgtagcg cttattgtag ctatgctagc gacagctatt cttggtgtcg
    12721 tgattgagtt tcttgcttac cgacctttgc gccactctac tcgtattgct gttttgatta
    12781 cggctattgg ggtttctttc ctattggagt atggaatggt ctatctggtt ggtgccaata
    12841 cccgtgcctt ccctcaagcg attcaaacag ttcgatatga tttgggagca attagcttaa
    12901 caaatgtgca gttaatgatt ttggccattt ccttgatttt gatgattttg ttacaagtca
    12961 ttgtccaaaa gactaagatg gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg
    13021 cacaattgat ggggatcaat gtaaaccgta cgattagctt taccttcgct ttgggttctg
    13081 ctcttgcggg tgcggctggt gttctgattg ctctttatta taactctctt gagcctttga
    13141 tgggggttac tccaggtctt aaatctttcg ttgccgcagt acttggtggt atcggaatta
    13201 ttcccggtgc ggctcttggt ggctttgtga ttggtctatt ggaaaccttt gcgacagcct
    13261 ttgagatgtc agatttccgt gatgccattg tttatggaat cttgttgttg atcttgattg
    13321 tccgcccagc tggtatcctt ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa
    13381 atttaaaagt taatattcta tggttactcc ttttgttagc tggctatagc ttgattagtg
    13441 tactggtttc agtcggagta cttaatctat tctatgtaca gattttacaa caaattggaa
    13501 ttaatattat tttggctgtt ggtctcaact taatcgttgg tttttcagga caattttcac
    13561 ttggtcatgc tggtttcatg gcgattggtg cctatgcagc agctattatt ggttctaaat
    13621 caccaaccta cggtgccttc tttggagcta tgcttgtagg ggctttgctt tcaggagcag
    13681 ttgccttact tgtcggcatt ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa
    13741 ctctgggtgt ttctgaaatt atccgtatct ttatcatcaa tggtggaagt cttacaaatg
    13801 gtgcggcagg tatcttaggg attcctaact ttacaacttg gcaaatggtt tacttctttg
    13861 tcgtgattac aaccattgca accttgaact tcttgcgtag cccaattggc cgttcaaccc
    13921 tctctgttcg tgaagatgaa atcgctgctg agtcagttgg ggttaatacg actaaaatta
    13981 aaatcatcgc ttttgtcttt ggtgccatta ctgcaagtat tgctgggtca cttcaggcag
    14041 gatttatcgg gtctgttgta ccgaaagatt acaccttcat caactcaatc aacgttttga
    14101 ttattgttgt atttggtgga ctcggttcca ttacaggtgc gattgtttcg gctattgttc
    14161 tgggaatttt gaatatgctt ctccaagatg ttgctagtgt gcgtatgatt atttacgctt
    14221 tggccttggt attggtaatg attttcagac caggtggact ccttggaacg tgggaactga
    14281 gcctatcacg tttctttaaa aaatctaaga aggaggaaca aaactaatgg cattacttga
    14341 agtaaaacag ttaaccaaac attttggtgg tctaacagct gttggagatg tgactcttga
    14401 attgaacgaa ggggaactgg ttggattaat cggtccaaac ggagctggga aaaccaccct
    14461 tttcaacctt ttgaccggtg tttatgaacc aagcgaggga acagtaaccc tagatggtca
    14521 ccttttgaat gggaaatcac cttataagat tgcctctttg ggacttggac gtactttcca
    14581 aaatatccgt ctctttaaag atttaacagt tttagataat gttttgattg cttttggaaa
    14641 ccatcacaaa cagcatgttt ttactagttt cttacgctta ccagcttttt acaagagtga
    14701 aaaagaatta aaggataaag ctttggaatt gttgaaaatc tttgatttag atggtgatgc
    14761 agagactctt gctaaaaatc tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc
    14821 ccttgctacg gaacctaaaa ttctcttctt agatgaacca gcagcaggta tgaacccaca
    14881 ggaaacagcc gaattgactg agttaattcg tcgtatcaaa gatgaattta agattacaat
    14941 catgttgatt gaacacgata tgaatctggt catggaagta acagaacgta tctacgtact
    15001 tgaatatggc cgtttaattg ctcaaggaac tccagacgaa attaagacca ataaacgcgt
    15061 tatcgaagct tatctaggag gtgaagccta atgtctatgt taaaagttga aaatctttct
    15121 gtgcattacg gtatgatcca agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa
    15181 gttgtttccc ttatcggtgc caacggtgca ggtaagacaa ctattcttcg caccttgtca
    15241 ggtttggttc gaccaagttc aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg
    15301 ccagctcaga aaatcgtggc aggtggtctt tcacaagttc cagaaggacg ccacgtcttt
    15361 cctggcttga ctgttatgga aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa
    15421 gaaaatcaag ctaacttgaa gaaggttttc tcacgctttc ctcgtcttga agaacggaag
    15481 aaccaagatg cagctactct ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct
    15541 cttatgtcaa caccaaaact tcttctttta gatgaaccat caatgggact tgccccaatc
    15601 ttcatccaag agatttttga tatcattcaa gatattcaga agcaaggaac aaccgtcctc
    15661 ttgattgaac aaaatgccaa taaagcactt gcaatctctg accgaggata tgtattggaa
    15721 acaggaaaaa tcgtcctatc aggaacagga aaagaactcg cttcatcaga agaagtcaga
    15781 aaagcatatc taggtggcta aaacaatcca gtggattgtt ttagtcggca gatgaagatt
    15841 acgaagtaat catcaatata gtccgggggc cctttttagt cggtggatga agattgcgaa
    15901 gcaatcatca aatccagagg attgttttag ccggtagatt gagattgcaa acaaatctgc
    15961 atctacattg aaagctgaat ttctaataat tgaaaaaatc gaatgaaacg tatcttacct
    16021 tcattcaggg agctcgattt tagagctctt tttgctagct tattcatact tttttgaatt
    16081 tcgaaaaaga aatgtaagcg tttgatagat ttacaaaaag attgtataat ggggataaga
    16141 atagaaaagg agaagtctca tggcagttaa agattttatg acccgcaagg tagtttatat
    16201 tagtccagat acaacagtat ctcatgcagc agatttgatg agagagcaag aattgcaccg
    16261 cttgcctgtt atcgaaaatg atcaattggt tggtttggtg actgagggaa ccattgcaca
    16321 agcaagtcca tctaaagcaa caagtctttc tatctatgag atgaattatc ttctgaataa
    16381 gacaaaagta aaagatgtca tgattcgcga tgttgtcact gtctcaggct atgctagtct
    16441 agaagatgca acttatctga tgttgaaaaa taagattggt attctccctg tcgtagataa
    16501 ccatcaagta tacggagtta ttactgaccg tgacgttttc caagcctttc ttgaaattgc
    16561 aggttatggc gaagaaggga ttcgtgtacg ctttgttaca gaagatgaag ttggtgttct
    16621 tggaaaaatt gtttctttga ttgtagaaga aaatttgaat atctcccata cagtcaatat
    16681 tccgcgtaag gatggtaagg tcattatcga agtgcaaatc gatggatcaa ttgatttacc
    16741 agccttgaaa gaaaaatttg aagcaaatgg tattcaagtg gaagaaatcg ctcgcacttc
    16801 agcaaaagtc ttgtaagaag ggaagcccaa aggcttcttt tttcatgaaa aggggattag
    16861 agaaaaagat ggaaagaaat gataaaatat gctataatga aataatgtaa aaaaggagta
    16921 tttatggaca tttcagtaat tcgtcagaaa attgacgcaa atcgtgaaaa attagcttct
    16981 ttcagggggt ctctttgacc tcgaagggct agaggaagag attgccatct tggaaaacaa
    17041 gatgacagaa cctgattttt ggaacgataa tattgcggcc caaaaaacgt cgcaagaatt
    17101 aaatgaatta aaaaacactt acaatacctt ccataagatg gaagagttgc aggatgaagt
    17161 cgaaatttta ttggattttt tggctgaaga cgagtcagtg catgatgaac tggtagcgca
    17221 gttagccgaa cttgataaga taatgaccag ctacgagatg actctactct tgtcagaacc
    17281 ttatgaccac aacaatgcca tcttggaaat ccatccaggt tctggtggta ctgaggcgca
    17341 ggactggggt gatatgttgc ttcgtatgta tactcgttat ggtaatgcta aaggctttaa
    17401 agtggaagtg ttggattacc aagcaggtga tgaggctggt attaagtcgg taactttatc
    17461 atttgaaggg cctaatgcct atggtctcct caagtcagaa atgggtgttc accgcttagt
    17521 gcgaatctca ccatttgact ctgccaaacg tcgccatacc tctttcacat ctgtagaagt
    17581 gatgccagaa ttggatgata ctattgaagt ggaaatccgt gaagatgata tcaagatgga
    17641 taccttccgt tcaggtggtg ccggtggaca aaacgtcaat aaggtttcaa caggtgtacg
    17701 tttaacccac attccaactg gaattgttgt ccaatcaaca gtggatcgta cccagtatgg
    17761 aaatagagat cgtgccatga agatgttgca ggctaagctc tatcaaatgg agcaagataa
    17821 gaaggctgcg gaggtagatt ctctcaaagg tgagaaaaag gagatcactt ggggaagcca
    17881 aatccgttct tatgtcttca cgccttatac tatggtaaaa gatcaccgaa ctagctttga
    17941 ggttgctcag gtagataagg ttatggatgg ggacctagat ggttttatcg atgcttatct
    18001 caagtggcga attagctaag atagaaagga actcacatgt caattattga aatgagagat
    18061 gtcgttaaaa aatacgacaa cggaacaact gctctacgcg gtgtttcggt tagcgttcaa
    18121 ccgggggaat ttgcttacat cgtaggacct tcaggagcag ggaagtcaac ttttattcgt
    18181 tctctgtatc gtgaagtaaa aatcgataaa ggaagcctat cagttgctgg ttttaatctg
    18241 gttaagatca aaaagaaaga tgtcccgctt ctacgtcgta gtgttggggt tgtcttccag
    18301 gattataaac tgttaccaaa gaaaactgtc tatgaaaata ttgcttacgc tatggaagta
    18361 atcggggaaa atcgccgtaa tatcaaaaga cgagtgatgg aagttttgga cttggttgga
    18421 ttgaagcata aggttcgttc ttttccaaat gaactctcag gtggggagca acagcgaatt
    18481 gcgattgcgc gtgcaattgt aaataatccc aaagtattga tagctgatga gccaacagga
    18541 aatctggatc cggataattc atgggaaatt atgaatctct tggaacggat taacctacaa
    18601 ggaacaacta ttttgatggc gactcataat agccagattg taaatacctt gcgccaccgt
    18661 gtcattgcca ttgaaaatgg ccgtgtcgtt cgtgacgaat caaaaggaga gtatggatac
    18721 gatgattagt agattttttc gccatttatt tgaagcctta aaaagtttga aacgaaatgg
    18781 ttggatgaca gtagctgctg tcagttcagt catgattact ttgaccttgg tggcaatatt
    18841 tgcatctgtt attttcaata cagcgaaact agctacagat attgaaaata atgtccgtgt
    18901 agtagtttat atccgaaagg atgtggaaga taatagtcag acaattgaaa aagaaggtca
    18961 aactgttaca aataatgact actacaaggt atatgattct ttgaagaaca tgtctacggt
    19021 taaaagtgtt accttttcaa gtaaagaaga acaatatgaa aaattaaccg agataatggg
    19081 agataactgg aaaatctttg aaggagatgc caatcctctc tatgatgcct atattgtaga
    19141 ggcaaacact ccaaatgatg taaaaactat agccgaagat gctaaaaaaa ttgaaggtgt
    19201 ctctgaggtt caagatggcg gtgccaatac agaaagactc ttcaagttag cttcatttat
    19261 ccgtgtttgg ggactaggga ttgctgcttt gttaattttt atcgcagttt ttttgatttc
    19321 aaataccatt cgtattacca ttatttcccg cagtcgcgaa attcaaatca tgcgcttggt
    19381 cggagctaaa aacagttata tccgtggacc gttcttgtta gaaggagcct ttatcggttt
    19441 attgggagct atcgcaccat ctgttttggt ctttattgtt tatcaaattg tttatcaatc
    19501 tgtcaacaaa tcgttggtag ggcaaaatct atccatgatt agtccagatt tatttagtcc
    19561 gttgatgatt gccctactat ttgtgattgg ggttttcatt ggttcattgg gatcaggaat
    19621 atccatgcgc cgattcttga agatttaggt aaaatagctg cttttatgag gagattgtaa
    19681 aatctccttt tttgctacaa gagtttttga aaagagatgc gcagaagaaa agagcttcca
    19741 aagaagtccc ccagagaaga cttcttgatg gctaatttga acttgaaatt tgactcacta
    19801 gaaatttttt agaaaaaagt gtaatttttt tataaaagcc tttacaaaaa aaattaaagt
    19861 ggtataatta aattatagaa ggtgcaaacg ttttcgtaaa acgtttgcct aaataaaaat
    19921 aaaggagatt tgaatgatga aagatacatt caaaaatgtc ttgtctttcg aattttggca
    19981 aaaattcggt aaggctttga tggtagttat cgcggttatg ccggctgctg gtttgatgat
    20041 ttcaatcggt aagtctatcg tgatgattaa cccaaccttt acaccacttg tcatcacagg
    20101 tggaattctt gagcaaatcg gttggggggt tatcggtaac cttcacattt tgtttgccct
    20161 agccattgga ggaagctggg ctaaagaacg tgctggtggt gctttcgccg ctggtcttgc
    20221 cttcattttg attaaccgta tcactggtac aatttttggt gtatcaggcg atatgttgaa
    20281 aaatccagat gctatggtaa ctactttctt tggtggttca atcaaagttg ctgattactt
    20341 tatcagtgtt cttgaagctc cagccttgaa catgggggta ttcgtaggga ttatctcagg
    20401 ttttgtaggg gcaactgctt acaacaaata ctacaacttc cgtaaacttc ctgatgcact
    20461 ttcattcttc aacgggaaac gtttcgtacc atttgtagtt attcttcgtt cagcaatcgc
    20521 tgcaattcta cttgctgctt tctggccagt agttcaaaca ggtatcaata acttcggtat
    20581 ctggattgcc aactcacaag aaactgctcc aattcttgca ccattcttgt atggtacttt
    20641 ggaacgtttg ctcttgccat ttggtcttca ccacatgttg actatcccaa tgaactacac
    20701 agctcttggt ggtacttatg acattttaac tggtgcagct aaaggtactc aagtattcgg
    20761 tcaagaccca ctatggcttg catgggtaac agaccttgta aaccttaaag gtactgatgc
    20821 tagtcaatat caacacttgt tagatacagt acatccagct cgtttcaaag ttggacaaat
    20881 gatcggttca ttcggtatct tgatgggtgt gattgttgct atctaccgta atgttgatgc
    20941 tgacaagaaa cataaataca aaggtatgat gattgcaaca gctcttgcaa cattcttgac
    21001 aggggttact gaaccaatcg aatacatgtt catgttcatc gcaacaccta tgtatcttgt
    21061 ttactcactt gttcaaggtg ctgccttcgc tatggctgac gtcgtaaacc tacgtatgca
    21121 ctcattcggt tcaatcgagt tcttgactcg tacacctatt gcaatcagtg ctggtattgg
    21181 tatggatatc gttaacttcg tttgggtaac tgttctcttt gctgtaatca tgtactttat
    21241 cgcaaacttc atgattcaaa aattcaacta cgcaactcca gggcgcaacg gaaactacga
    21301 aactgctgaa ggttcagaag aaaccagcag cgaagtgaaa gttgcagcag gctctcaagc
    21361 tgtaaacatt atcaaccttc ttggtggacg tgtaaacatc gttgatgttg atgcatgtat
    21421 gactcgtctt cgtgtaactg ttaaagatgc agataaagta ggaaatgcag agcaatggaa
    21481 agcagaagga gctatgggtc ttgtgatgaa aggacaaggg gttcaagcta tctacggtcc
    21541 aaaagctgac attttgaaat ctgatatcca agatatcctt gattcaggtg aaatcattcc
    21601 tgaaactctt ccaagccaaa tgactgaagc acaacaaaac actgttcact tcaaagatct
    21661 tactgaggaa gtttactcag tagcagacgg tcaagttgtt ggtttggaac aagtaaagga
    21721 tccagtattt gctcaaaaaa tgatgggtga tggatttgca gtagaacctg caaatggaaa
    21781 cattgtatct ccagtttcag gtactgtgtc aagcatcttc ccaacaaaac atgcttttgg
    21841 tattgtgacg gaagcaggtc ttgaagtatt ggttcacatt ggtttggaca cagtaagtct
    21901 tgaaggtaaa ccatttacag ttcatgttgc tgaaggacaa aaagttgcag caggagatct
    21961 ccttgtcaca gctgacttgg atgctatccg tgcagcagga cgtgaaactt caacagtagt
    22021 tgtcttcaca aatggtgatg caattaaatc agttaaatta gaaaaaacag gttctcttgc
    22081 agctaaaaca gcagttgcta aagtagaatt gtaatatact tgaggttgga agctgtattc
    22141 caacctctta ttttgggaga aaagaatgaa atttttaaca ctcaatactc acagttggat
    22201 ggagaaagaa gcagaggaaa aattccagat tttgcttgaa gatattcttg aaaaggacta
    22261 tgatttgatt tgtttccaag aaatcaatca ggagatgacc tcgtcagagg tggaggttaa
    22321 tgacctttat caagctttgc cagcagctga gcctattcac caagaccatt atgttagact
    22381 cttggttgaa aagttgttag agcaagggaa aaattactac tggacctggg cttataacca
    22441 tatcggctat aaccgctacc acgaaggtgt ggctatcttg tctaaaacac ctattgaagc
    22501 cagagaaatt ttggtttcag atgtggatga tccaacagac tatcatactc gccgtgttgc
    22561 cctagctgaa actgtagtcg atggcaagga gctagcagtt gccagtgttc atctctcttg
    22621 gtgggataaa ggtttccaag aagaatgggc acgatttgag gctgtcttga aaaaattgaa
    22681 caagccactt ttactagctg gagattttaa caacccagca ggtcaggaag gttaccaagc
    22741 tattttagct agtccattag gcttacaaga cgcatttgaa gttgctcaag agaaaagtgg
    22801 tagctatact gttccgcctg aaattgatgg ctggaaaggg aacactgaat cccttcgaat
    22861 cgattatgtc tttactacca aagagttagc ggtggaaaat ttacatgtcg tatttgatgg
    22921 taacaagagt ccacaagtga gtgatcacta tggcttgaat gctatgttaa actggaaata
    22981 ataactgaaa agaggttgga actataaaat tccagccttt tcttactaga gaagctactg
    23041 gaaatagcct aaataagtga gactactgta atggaataaa atatggtata attgataaga
    23101 tagatagaat cgaggatgtt atgtcattta cgaaatttca atttaaaaac tatattagag
    23161 aagccttgga ggagttaaaa tttacaactc caacagaggt gcaagacaag ttgattccta
    23221 ttgttttggc aggtcgtgac ctagtaggag aatcaaaaac aggttcaggt aagactcata
    23281 ctttcttgtt accgattttc cagcaattag atgaagctag cgatagtgta caagcagtga
    23341 ttactgcacc gagtcgtgag ttggctactc aaatttacca agtagcgcgt cagatttcag
    23401 ctcactcaga tgtcgaagtt cgtgtggtta attatgtggg tggtacggat aaggctcgcc
    23461 agattgagaa attggaaagc aatcagcctc atattgttat tggaacacca ggccgtatct
    23521 acgacttggt taaatctggt gatttagcta ttcataaagc caagacattt gttgttgatg
    23581 aagcagatat gaccttggat atgggattct tggaaattgt tgataagatt gctggcagtc
    23641 ttccaaaaga cttgcaattc atggtcttct cagcgactat cccacaaaaa ctgcaaccat
    23701 tcttgaaaaa atacttatca aatcctgtta tggagaaaat taagactaaa acggttattt
    23761 ctgacaccat tgataattgg ttgatttcga ccaagggaca tgataggaat gctcaaattt
    23821 accaattgac tcagttgatg cagccgtatt tggcaatgat ttttgttaac actaaaacgc
    23881 gtgctgatga attgcattca tatctgactg ctcaaggctt gaaggttgca aaaatccatg
    23941 gagatattgc ccctcgtgaa cgcaagcgaa tcatgaatca ggtgcaaaat ctggattttg
    24001 agtatattgt cgcaacagat ttagcagcgc gtgggattga cattgaaggt gtcagccatg
    24061 tcatcaatga tgccattccg caagacttat ctttttttgt tcaccgtgtt ggtcgtactg
    24121 gacgaaatgg cctaccaggt acagctatta ccctttatca gccaagtgat gactcggata
    24181 tccgtgagtt ggagaaattg ggaatcaagt ttagtcctaa gatggtcaaa gatggggaat
    24241 ttcaagatac ctatgaccgt gatcgtcgtg ccaaccgtga gaaaaaacaa gataaacttg
    24301 atatcgaaat gattggtttg gttaaaaaga aaaagaaaaa agtcaaaccg ggttataaga
    24361 agaaaattca atgggcggtt gatgaaaagc gccgtaaaac taagcgtgct gaaaatcgcg
    24421 ctcgcggtcg tgcagagcgt aaagctaaac gccaaacatt ttaatagaaa ttgttggagt
    24481 actgagctcc aactttttta tttatgagaa cgaactatct aaaccgaaac actacattaa
    24541 agactgcaaa ttgcgattaa aaatggtata atgataaagt tatatagtcc cgataagatg
    24601 gtaggtattt attacgaaga gttttcctat cagtagtttg caattcgcaa agaatgacgg
    24661 cttcgaggtt gctcgtcttt ctacggttgc cgccatactg cggtcaccct atgcgcctta
    24721 ctagcttcag aaataaaaaa gtatcgtttt tatttctgaa gctagtaact cttagataat
    24781 ggaaattcct atcagtactt tgtaactcta taacaatatt ttttaagggg ggacattttt
    24841 atgtcagaac gtaaattatt cacgtctgaa tctgtatctg aggggcatcc ggataagatt
    24901 gcagaccaaa tttcagatgc gattttggat gctattttag caaaggatcc agaggcgcac
    24961 gttgctgctg aaacagctgt atatactggt tctgtccacg tttttggtga aatttctaca
    25021 aatgcctatg tggatattaa ccgtgtggtt cgtgatacca ttgcagagat tggttatacc
    25081 aatacagaat atggattttc tgctgagacg gtgggagtac acccatcttt ggtggaacaa
    25141 tctcctgaca tcgctcaagg tgttaacgaa gccttggagg ttcgtggaaa tgctgatcaa
    25201 gatccactgg acttgattgg agcaggtgac caagggctca tgtttggatt tgcagtagat
    25261 gaaacagaag agctcatgcc attgccaatt gcactcagtc ataaattggt tcgtcgtctg
    25321 gcagaacttc gtaagtctgg agaaattagc tatctccgtc cagatgcaaa atcacaagtt
    25381 acagttgagt acgatgaaaa tgaccgtccg gtacgtgtag atacagtcgt tatttctact
    25441 cagcatgatc cagaggccac taatgaacaa atccatcaag atgtgattaa caaggtcatc
    25501 aaagaagtta ttccatcttc ttatcttgat gataagacaa aattctttat caatccgaca
    25561 ggtcgttttg taatcggtgg tcctcaaggg gactcaggtt tgactggtcg taagattatt
    25621 gtagatactt atggtggcta ctctcgtcat ggtggtggtg ccttctctgg taaagatgcg
    25681 actaaggtgg atcgttcagc ctcttatgcg gctcgctata ttgccaagaa tatcgttgca
    25741 gcaggccttg ctaagaaggc agaagtgcag ttggcctatg ctatcggtgt tgcgcaacct
    25801 gtttctgttc gtatcgatac tttcggtaca ggaacagtag ctgaaagtca acttgaaaaa
    25861 gcggctcgtc aaatctttga ccttcgccct gcagggatta tccaaatgct ggacctcaag
    25921 cgtccaattt accgtcaaac atcggcttac ggtcacatgg gacgtacaga tattgatctt
    25981 ccatgggaac gtttggataa ggtagatgct ttgaaagaag cagtaaaata agattttaag
    26041 aggggaacgt cctctctttt ttatagtttt taactatact gggatactgt tctgaaaatc
    26101 cattttgcga aagtagagat ttacatgtat agtagattga aactagaata gtacacctca
    26161 acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttctc ctgttcttgt
    26221 ttcattttac tatatttctt taaaaatgat aaaggttgag atttctcctc gtaatagata
    26281 atcatgggga tatttcaatc caaagtttta ttcgttatca cttgactatt gcaaggtttt
    26341 ctagagcaac agagtcatgg aatggactca tggttgagat ttctccttgt tgcttggact
    26401 tcattcaaaa gtctgttacc caagccttgt tcaaacttcc aatacactag ctgtttccat
    26461 agcatgactt ctgtactaga ctttcttttc cgaataaata gatagaacca cagaatctag
    26521 taaacctaga attaaaatta tggtataata ttagcaataa aagaaatctg gaggattaga
    26581 atcatggtat caacgaaaac acaaattgct ggttttgagt ttgacaattg cttgatgaat
    26641 gcagcaggtg tggcttgtat gacgatagag gagttagaag aggtcaaaaa ctcagcggca
    26701 ggaacctttg ttactaagac agcgaccttg gacttccgtc aggggaatcc tgagccacgc
    26761 taccaagatg ttccacttgg ttccatcaac tctatgggct tgccaaataa tggcttagac
    26821 tattatttgg attatctttt agatttgcag gaaaaagagt cgaaccgaac tttcttctta
    26881 tctctggtcg gcatgtctcc agaggaaacc catactattt tgaaaaaagt ccaagagagt
    26941 gattttcgtg gtctgactga gctaaatctt tcctgtccaa atgttccagg taaacctcag
    27001 attgcctatg attttgagac aacagaccgg attttggcag aagtgtttgc ttacttcacc
    27061 aaacctcttg gaattaaatt gccaccttat tttgatattg ttcactttga ccaagcggca
    27121 gctattttca acaaatatcc gctcaagttt gtcaactgcg ttaactctat cggaaacggc
    27181 ctctatatag aagacgaatc tgtcgttatt cggcctaaga atggttttgg tggaattggt
    27241 ggagaataca tcaaaccgac tgctctagcc aatgttcacg ccttttatca acgtttaaat
    27301 cctcaaatcc aaattatcgg aacaggtggc gttctgactg gtcgagatgc ctttgaacac
    27361 atcctctgtg gagcaagtat ggtgcaggtg ggaacgaccc ttcacaaaga aggcgtcagt
    27421 gcttttgacc gcattaccaa tgaactgaaa gcaatcatgg tggaaaaagg ctacgagagc
    27481 ttagaagatt tccgtgggaa attgcgctat attgactaaa ttaaatcgaa aaatcagaag
    27541 aaagaaggga cgatgctagc cattgaagaa agtcagaagt tgactttatc aaatttaccg
    27601 agcctgagcc tatttacagg gacagatcag ggtcagtttg aagtgatgaa gagtcaaatg
    27661 ttgaaacaga ttgggtatga ttctgctgac ctcaactttg cctactttga tatgaaagaa
    27721 gtagtttaca aggatgtgga actggagttg gtcagccttc ctttctttgc ggatgagaaa
    27781 atcgtgatat tagattattt tatggatatc acgactgcta agaaacgctt tttgacagat
    27841 gatgagctta agtcatttga ggaatacctt gacaatcctt ctccaacaac caagttgata
    27901 atctttgcag aaggaaagct ggatagcaaa agacggttag tcaaattact taagcgtgat
    27961 gccaaggtct tcgatgcagt agaagtaaaa gaacaagaat tgcgccagta tttccaaaag
    28021 tggagtcaga aacaaggtct gcagtttacc aatcattctt ttgaaaatct cctcatcaag
    28081 tcggggtttc aatttagcga aatccagaaa aatcttctct ttttacagtc ctataaggcg
    28141 aattctgtta tcgaggaaga ggatattgtt aacgcaattc ccaagacctt gcaggacaat
    28201 atttttgatt taactcagtt tattctgact aaaaagatgg atcaggcgcg cgatttagtg
    28261 agagacttga ccttgcaagg ggaagatgaa atcaaactga ttgcagtcat gctgggacaa
    28321 tttcggactt ttactcaggt gaagattttg gcggagtctg gccaaacaga atcgcagatt
    28381 gcaagtagtt taggtagtta tctgggacgt aacccaaatc cttatcaaat caagtttgca
    28441 ttaagagatt cgagaggact ttctttgagc tttctgaagc aagctatttc ctatttgatt
    28501 gagacagact atcagattaa gacaggtctt tatgaaaaag gtttcctttt tgaaaaggca
    28561 ctcttacaga ttgctagtca ggtcaattga catttgttga aactacaacc cgcgtcagga
    28621 ttatcttgtc gtgggtttct tgctgatttg cttattttat tagaaagtat atcagtgatt
    28681 tccttatcta taagcaaaaa acttgaaaaa agtgaatgtt tgcgttatca ttttcatata
    28741 gaaagaaaaa gaggtattac agatggctat tatcttacca gaacttccat atgcatacga
    28801 cgctttggaa ccatacatcg atgcggaaac aatgcatttg caccatgaca aacaccatca
    28861 aacttatgtc aacaatgcca atgcagcttt agaaaaacac cctgaaatcg gtgaagacct
    28921 tgaagccttg cttgctgatg tagaatctat cccagctgat atccgtcaag cacttatcaa
    28981 caatggtggc ggacacttga accacgctct tttctgggaa ttgatgactc ccgagaaaac
    29041 agctccttca gcagaactgg cagcagcaat cgatgcaaca tttggttcat ttgaagaatt
    29101 ccaagcagcc ttcactgcag cagcaacaac tcgttttggt tcaggttggg catggttggt
    29161 tgtcaacaaa gaagggaaac ttgaagtgac ttcaacagca aaccaagaca caccaatctc
    29221 agaaggtaaa aaaccaatct tgggcttgga cgtttgggaa catgcttact acgtgaaata
    29281 ccgcaacgtg cgtcctgact acatcaaagc tttcttttca gtaatcaact ggaataaagt
    29341 agatgaattg tacgcagctg ctaaataatg atagttggag ggaagaattg ttcttctctt
    29401 ttttaggtta taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa
    29461 acgtgctaac tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat
    29521 atctatgcga aaagaaattg cacctgaatt atacaattat aacaagtttc ctggtccgga
    29581 gttccattta cacggggaca aggtcgaaac ggaagggata gctttttcct tggttgaaaa
    29641 tatcaaggat gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa
    29701 gtttgattat atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa
    29761 ggatgaccga acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga
    29821 gtattgtagt tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc
    29881 atttgacaag aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc
    29941 gactcaaact aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca
    30001 gcattctcag aaagaggaca agggacaacg tcattttgtc attcgtcaga agtgagtaga
    30061 gaataaggag aagaaatgaa accctcaatt catagtttgg tacatcaaac catgcaggaa
    30121 tgggtattgg agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac
    30181 cgtaaacgtg tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag
    30241 ctcaatgacc agtttgtggt caatcccttg aaacaacgta ttgtgcaaga gtctgctgat
    30301 ggtacagtca aatatctctt tgaattgccc gacggtatgt taattgagac tgtactcatg
    30361 cgtcaacact atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt
    30421 accttctgtg cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta
    30481 gcgcaaatca tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcatcagc
    30541 catatcgttg tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc
    30601 gtttgtacta tcaatgatga taaaggaatg gctatcggtg ctcgtcacat cacgatttca
    30661 acctcaggtt tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt
    30721 gccgtgtctc ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa aattaaccgt
    30781 gcctttccga ttgaaaaact ctttgctgct attgaatact atattgagac aacaaaccgt
    30841 cgtgtaacct ttgaatatat catgcttaat gaagtcaacg acggtgtaga acaagccttg
    30901 gaattggctg aattgctcaa gaacatcaag aaattgtctt atgtaaactt gattccttat
    30961 aacccagtta gtgagcatga ccaatatagc cgtagtccca aagagcgcgt gttggctttc
    31021 tatgatacgc ttaagaaaaa aggggtcaac tgtgtggttc gtcaagagca tggtacagat
    31081 attgacgcag cttgtggaca attgcgctct aacacaatga aacgtgaccg ccagaaggca
    31141 gtcgcagcgg taaatcctta atgatgaaga agacttataa tcatattttg gtctggggag
    31201 tcattttcta tagcatttgc attgtctgtt tttgctttac tcctcaagaa caatctaccg
    31261 tgggagtggg aactccaggt attcagcatc ttggacgcct ggtttttctt ttgactcctt
    31321 tcaattctct ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt
    31381 tacaaaatat cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat
    31441 ttccaaattt gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa
    31501 tcgagtgtac gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg
    31561 atgatttgtg gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac
    31621 ataaaaacaa ggtaaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt
    31681 tttggtgacc gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg agaacatatc
    31741 ggcctggtcg gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa
    31801 atgctgccag atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat
    31861 cagcactctg tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat
    31921 gagcttttca aagctgaagc tcgtatcaat gacctctata tgaaaatggc tgaagacggc
    31981 gcggatgttg atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt
    32041 gatttctata ccttggatgc taagattgac gaagtagcgc gtgctcttgg tgttatggac
    32101 tttgggatgg atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg
    32161 gcaaaacttc tccttgaaaa gcctgatatt ttgctgttgg acgagccgac caactacttg
    32221 gatgctgagc atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt
    32281 cttatttcgc acgatattcc attcctcaat gacgttatta atattgtcta tcatgtggaa
    32341 aatcaacagc tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg
    32401 aagaaatctc agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag
    32461 gactttgtgg ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa
    32521 aagaaattgg ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt
    32581 gatttcaaac cagctcgtac accagggcgc tttatcttcc aagccaagaa cttgcaaatt
    32641 ggttacgacc gtcctcttac taagccttta aatcttacct tcgaacgcaa tcaaaaggtt
    32701 gcgattattg gtgctaatgg tattggaaaa acaactctct tgaagagtct cttaggcatt
    32761 atctcgccaa tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag
    32821 caggaagtag aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct
    32881 gcccttaatc aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat
    32941 attgaaagcc agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc
    33001 ttgatgaatc gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg
    33061 gatgcaaagg atgagctcaa acgcgctctc aaagaataca ggggatctat ccttatggtc
    33121 tgccacgagc cagactttta tgaaggttgg atagaccaaa tatgggattt taataattta
    33181 acttaagaat gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt
    33241 tttaagattt aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag
    33301 ttggcttgtc tttttcatct ttttcggctt tagcaatctt atccacaaca tccataccgt
    33361 caatcacttg accaaagact gggtgtttgc catctagact agggtttcca ccttctttgt
    33421 aggcttcgat aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag
    33481 agttttggtt gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag
    33541 caagagcacc acggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt
    33601 tgtctttagt cttatccttg tcatgccata tggactgacc acctgtaccg tccccttttg
    33661 gatctccagt ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt
    33721 agccttcttt ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga
    33781 gtttaatgcg aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa
    33841 cttccttaga tagttgtggg aaattggcgt tttcgtttgt taaagcatcg tttaactcct
    33901 tggcagattg ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat
    33961 catcaccacg cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta
    34021 aaagaagggt tgctagtttt ttcattctga tcctctcaaa aattcattta taccattgta
    34081 ccctaaaagg aagtggattt caaatattag tagtttacag aactggctta gataatagtt
    34141 gggatttcat catcatcttg aaaatcttca acttcttcaa cttcttcccc agtaaatggt
    34201 ttctgaaaag aacttagtat aaaacgggca attggttcaa caattaggaa atttagagga
    34261 agagctgcaa taaagtttac gaaccaggcg cttagatagg tattgggtgt gatagcaatg
    34321 ccattgtaaa aaagtccata gaaggacatg aaagtgacca gctaattctt cttctgaaaa
    34381 atgctcatga agggcttgat ccaggtcgca agatttcatt ttagaaagtc cagtaactcc
    34441 cttcttcttc aggatattct ttttcatggt attatttaga tggtcaagtg agtcaaaaga
    34501 agtttcgaca agagcatacc ctttttctac cagagttttt agatgtttag gggcatcaat
    34561 accataagtg tactcaaagt attttggaaa ccagatctta agaaagctcg taaagctagc
    34621 cagttctcta aacgctaaga actagctaca acacagcatt tacaacactt catggttcac
    34681 accatggggt gttttttaat gattttaagc aaaattcaca cttaattgaa agttatttaa
    34741 attagatgaa aatttatttt ttgaaaaagt gggaaaacat tgattctaag cgaattttga
    34801 atcatattcg aatgggagtt tttaaaatca tgtttcagtg gtaaaagtac caaactggat
    34861 tctccatagt aaaatgatat ctcctgctag tgaatcatct gctaataagt ccatatttcg
    34921 cttgggactt agaagccaag tatccaactc tcgttcaggc gatatgaagg gtttgacttg
    34981 gtgttcttta taaaattttt ctaaaatagt attcacggat agcatctttc aaacatttat
    35041 ttcctattct aacaaatttc taaatgcttt aagaaattta tagtctgtca agtttttttc
    35101 ttgacacctg ccagaaatct gctataatag aacatgtgct aaatagctca gctatttcac
    35161 cgaaataaaa aattaaagaa atgagacttt aaaaatggca gttaaaatcc gtttgactcg
    35221 tatgggttct aagaaaaaac ctttctaccg tatcaacgta gcagattcac gttcaccacg
    35281 tgacggacgt ttcatcgaaa cagttggaac ttacaaccca cttgttgctg aaaaccaagt
    35341 aactttgaaa gaagaccgcg ttcttgcatg gttggctaat ggagctcaac cttcagacac
    35401 agtacgtaac atcctttcaa aagaaggcgt attgaaaaaa ttccacgatt ctaaattctc
    35461 aaaataagtt taaagtaggt tgacagatgg atacgattga aaatctcatt attgcgattg
    35521 tgaaaccctt aatttcacaa ccagatgcct taactatcaa gattgaggat acaccagaat
    35581 ttttggaata tcatttgaat cttgatcaaa gcgatgtggg tcgtgtaatc ggtcgtaagg
    35641 gtcgcactat ttctgcgata agaacgattg tctactctgt cccaactgaa tacaaaaaag
    35701 taagaatcgt tattgacgaa aaataagaag ggcgggacgg atgtctcgct tttttgtgtg
    35761 gaatagaaga tatagtaaaa tgaaataata acaggacaaa tcgatcagga cagtcaaatc
    35821 gatttctaac aatgttttag aagtaaaggt gtactattct agtttcaata tactataaaa
    35881 gattgaacgt ttaggcaatt ccaagactac ttaatcgaac attaacagca gtctcggact
    35941 gatgaaggtc tttttatgaa gttagtggag gaagtcggag aagtagccga ggttttgaat
    36001 aggcgctctg gtcgaaaaga agggatagga ttcgaacgag gaacttgcca gagaactggc
    36061 tgatatcatt tactacaccg tcgcaatcgt agctattaat catattgacc ttaccaagac
    36121 tgtctttgag aaagacaaaa ccgcagccgt taattaccaa cataaacata atttggaagg
    36181 attattgaag ggaaagtaga gatattgtcc ccttcctcca acttgagaaa atccttggaa
    36241 cgtgataaaa taaaggataa ggatttttaa taattcatta tatagaatca gtggatttct
    36301 ttatgaagag gtttgaagta tctacagaaa ttggtagcct ctctgttact tatcaaaagc
    36361 aaaagaaagt gctagtttgt ctaaacggag caggtttgct accaagttat gaaaattttt
    36421 cacttatact tgaaaaacct cctcctacaa ttggttattt gacaattgat tttccgaaca
    36481 caggtaggag tccgattcat gaccaagctg gaaaaaatct agataatctt gcagatgcgg
    36541 tttatgaagt acttgaagaa ttaggaattt ctgaatatat actttgtgca catagttgga
    36601 gtggaatttt agcttgcaaa ttactcgaga aaccaattaa gcgtcagact ttagtagcaa
    36661 ttgaaccgac aactaaaaaa gtcatgtttg ctgatttttc agaaaatcct tatccagaaa
    36721 tggaagagca gatgaggctg attgacgagt gtggtcctga actttatttt aagaacttaa
    36781 ctcaagcaac atttagtcct gaaacgaata aaaaaatctg ggaattaatg caagaaaaag
    36841 gcttagagtt ggaaaatcaa gatccagaat ttcagatatc tggagagatt actgaggaag
    36901 attttgagga tgtatctata gaagctcata ttcctgtatt tgttttttgt cagccttata
    36961 gagaaaaaga gtacagagaa tcagaatatt ggacttccaa tactaaactc attttaggag
    37021 ggaatcacca ttatttacaa tggtcagaat cggaaaaaat tgcggctatt attcgagaat
    37081 tgttagaata agatggaaaa aaggagatta caggagacaa gatgaactac tttaatgttg
    37141 ggaaaatcgt taatacgcag ggattacagg gtgagatgcg agtcttgtct gtgacggatt
    37201 ttgcagaaga acggtttaaa aaaggagctg agctggcttt gtttgatgaa aaagatcagt
    37261 ttgtccaaac agtgaccatc gctagccacc gtaaacagaa gaactttgac attattaaat
    37321 tcaaagatat gtaccatatc aatactatcg aaaagtacaa gggatacagt ctcaaggtcg
    37381 ctgaggaaga tttgaatgac ctagacgatg gtgaatttta ctatcacgag attatcggtt
    37441 tggaagtcta tgagggtgat agcttggttg gaaccatcaa ggaaatcctg caaccaggtg
    37501 ctaatgatgt ctgggtggtc aaacgaaaag gcaaacgtga tttgctttta ccttatatcc
    37561 caccagtggt tctcaatgtt gatattccaa ataaacgggt cgatgtggaa atcttagaag
    37621 ggttagacga tgaagattga tattttaacc ctctttccag agatgttttc tccactggag
    37681 cactcaatcg ttggaaaggc tcgagaaaaa gggctcttgg atatccagta tcataatttt
    37741 cgagaaaatg ctgaaaaggc ccgtcatgta gatgatgagc cctacggagg cggtcagggc
    37801 atgttgctca gagtacaacc tattttcgat tcctttgatg ctattgaaaa gaaaaatccg
    37861 cgcgttattc tcctcgatcc tgctggaaag cagtttgatc aggcttatgc tgaagatttg
    37921 gctcaagagg aagagctaat ctttatctgt gggcactatg agggttatga tgagcgcatt
    37981 aagaccttgg taacagatga gatttcccta ggcgactatg tcctcactgg tggagaattg
    38041 gcagctatga ccatgattga tgctacagtt cgcctgattc cagaagtgat tggcaaggag
    38101 tctagccacc aagatgatag tttttcttca ggtcttttag aatatcctca gtacacacgt
    38161 ccttatgatt atcgaggcat ggtcgtgcca gatgtattga tgagtggcca ccatgaaaag
    38221 attcgtcagt ggcgattgta cgagagttta aagaaaacct acgagcgcag accggattta
    38281 cttgaacatt atcaactgac agtagaagaa gaaaaaatgc tggcagaaat caaagaaaac
    38341 aaagaataaa ggagaaacct atgcaagtaa tcaaacgtaa tggcgaaatt gctgaattta
    38401 atccagataa gatttaccaa gccatcttga aggcagccca aactgtttat gttttgacag
    38461 atgatttgcg tcaaaatctt gctcaagtca ctaagaaggt agttttggat ttacaagaag
    38521 ccaaggtgga acgtgcgact atcagtatga ttcaatctat ggttgaacat cgtttattgg
    38581 gcgcaggtta cattaccatt gcagaacact acatttccta tcgtttacaa cgtgacttgg
    38641 aaagaagtgg ttatggagat catatcgcag ttcatttaca ttttgaacaa attcgctaag
    38701 aaaaaagagt gggatgaagc aactacatct cactctttct taaatctatt tttttgggct
    38761 gtttggacag ttgaggggac aaatcgcagg cgttgaatat cgcttatacg gataatccgg
    38821 ctcacatttt tggaaaaatt tttcacgata atttgctggc cttgctgatc atatttgatg
    38881 atgtcacctg taaagcttgt ctcagataag ataaggtgaa cagcggtttg tttctggata
    38941 gcctcttcaa tagtggctgt aagggagttg gtttcagtct ggtcaggttg gtcatatcca
    39001 tttaaaaaat catgtatttt atttagaact tgctggaatt tatgtctcat attggcctcc
    39061 cttcttttat atcaatatta tataaaattt tcctaaaatc tacaagattt tacgaataaa
    39121 ctaatgaaac taaaaaagga gaagaaaatg gcagaattta catttgaaat cgaagagcac
    39181 ttgttgactc tttctgaaaa cgaaaaaggt tggaccaagg aaattaaccg tgtgagcttt
    39241 aatggtgccc ctgcaaagtt tgatattcgt gcttggagtc cagaccatac taaaatgggc
    39301 aaagggatta ctctctcaaa tgaagaattt caaacgatgg tggatgcctt taaaggcaac
    39361 taatactctt cgaaaatctc ttcaaaccgc gtcagctttg ccttgccgta tgtatggtta
    39421 ctgacttcgt cagtttcatc cacaacctca aaacaatgtt ttgagctgac ttcgtcagtt
    39481 tcatccacaa cctcaaaaca atgttttgag ctgacttcgt cagtttcatc cacaacctca
    39541 aaacagtgtt ttgagcagcc tgcggctagc ttcctagttt gctctttgat tttcattgag
    39601 tataagtttt caaaataaaa gaaaaggata ttgagtcatg ataactcggt atcctttttt
    39661 agttagtaaa gtaagcctga tttttaaggc gttgaagtag gggacggcta ataaaactaa
    39721 tagccagaag tttgccaagg tctggaatga taaagggaag aacccccaca acaagagctt
    39781 tttcaaatgc cattccagct aggaaatgca agctgagaat cccgccgaca aagacaaggg
    39841 catcacccaa gaggtttgca agaaaaatct taacaacacc actcttgctg ttggttagag
    39901 aggaagtaag tccagagtaa acgagataaa accaaagata gcctgcagta gggccaacta
    39961 aagcctgaaa accagctcca cctcctgcaa agacaggaag accgatagca cctagaagaa
    40021 gatagagtcc agcagaaagt acagcctctc tcggtctaaa gacagtagca atcaagccga
    40081 ttgcaaagtt ttgcagagtg aagggaacag gtccaattgg aagactgatt tgtgccaaag
    40141 cagcaatgag agcagcccca atagcaggga tagcataaac gtgagctttt ttcaaaatag
    40201 ttaacctctt ttctaatgta tagtaactat tatactcata taggagtcga tgtcaaccat
    40261 tttttaaaaa caaggtaaca aaaactgtaa cagccgattt tcgtgactag tcaagttgga
    40321 taattttttt gttgattcga aaatcattaa aaaagaagca gacatattta tatcagcttc
    40381 ttttgtttcg attaacgcat ggttacaaat tcttcagatg cagttgggtg aattgccaca
    40441 gttgcatcaa agtcagcctt ggttgctccc attttgatag caacggcaaa tccctgaatc
    40501 atttcatcaa cgccgtagcc aattccatga agtccgacaa ctttttcttc tgaaccagct
    40561 gttatgagtt tgaaacggga ttcttgacgg ttgcgagtgc aagcagagta catagatgca
    40621 aagcttgatt tataaacctt gatttggtct tgaccgtatt ctttaatagc ttgctcttct
    40681 gtcaaaccaa cagttccgat agcagggtgt gaaaagacaa cagttggaat agttgagtaa
    40741 tccatttttg cagtagtttt tccgttaaag agacgttcag atagggtacg tccggccttg
    40801 attgcaactg gagtcagttc tttctcgccc gttacatcac ctagagcata gagtccctca
    40861 acaacagtat tttggtattc atccacttgg ataaagccac gttcgttcag agtcactcca
    40921 gctttttcaa gttgcaagcc cttaacgttt ggacggcggc ctgtagccca gataacttgg
    40981 ctagctgtgt gactagtacc atcttcgaaa tgaatggtaa tgccgtcagt agttttttct
    41041 aacttgacag ggactttgtg agtgtgaagt ggtaagtttg ttctttccat ttccttgacc
    41101 aaaccttcaa cgatgtagga atcaaaacca cgtaaaggac gatcgcggcg aacaaagaga
    41161 tctgtcttga caccaaaagt gtggagtacg ccagctaatt caacggcgat ataaccagcg
    41221 cctagaatgg caactgactc tggaagttct tcccaggcaa atacatcatc agaagagcca
    41281 cctagctcag caccaggaat attaggaata cttggatggg cacctgtagc aatcacgata
    41341 tgtttagcac gaatcagttc accatttacg cttacagtat gagaatctac aaattcagca
    41401 tgaccttcaa tcaagtctac accgttgcgt ttaaaactac catcataaga agaacgagcg
    41461 cgatcaatgt aggcttcacg attgcgacgt agggttgcaa agtcaaagtt aagatcagta
    41521 gtcttaaagc cgtagtcttc tccaaattga tggaaagtct cagcgatttg cgccccgtac
    41581 cacatgattt ttttaggaac acaaccgacg ttgacacagg ttccacctaa tttcttttcc
    41641 tcaataacgg ctgctttggc tccatgttca ccagcacggt tcatggtagc gattcctccg
    41701 ctacctccac cgatagcaat gatatcatat tctctcattg aaaactcctt tgtaatcttt
    41761 taaatagtag agcgtctttt ttgatagtta tattttattc tttttttgat ttgattgcaa
    41821 aaatctgcta cgcacaaaaa attgcaaaaa agcttgccaa ataagtcaag atagtgtatt
    41881 atatatctag tacaatagaa aagcaaaatt ccgaacgatt gtttaatcct gaactgccat
    41941 tatttccatc tgaactgcat tgtttgctgg agggaaattt ggtataatag caaagtattg
    42001 taaaaaagaa aaggagtttc attatgaaga aaaagaatgg taaagctaaa aagtggcaac
    42061 tgtatgcagc aatcggtgct gcgagtgtag ttgtattggg tgccgggggg attttacttt
    42121 ttagacaacc ttctcagact gctctaaaag atgagcctac tcatcttgtt gttgccaagg
    42181 aaggaagcgt ggcatcctct gttttattgt cagggacagt aacagcaaaa aatgaacaat
    42241 atgtttattt tgatgctagt aagggtgatt tagatgaaat ccttgtttct gtgggcgata
    42301 aggtcagcga agggcaggct ttagtcaagt acagtagttc agaagcgcag gcggcctatg
    42361 attcagctag tcgagcagta gctagggcag atcgtcatat caatgaactc aatcaagcac
    42421 gaaatgaagc cgcttcagct ccggctccac agttaccagc gccagtagga ggagaagatg
    42481 caacggtgca aagcccaact ccagtggctg gaaattctgt tgcttctatt gatgctcaat
    42541 tgggtgatgc ccgtgatgcg cgtgcagatg ctgcggcgca attaagcaag gctcaaagtc
    42601 aattggatgc aacaactgtt ctcagtaccc tagagggaac tgtagtcgaa gtcaatagca
    42661 atgtttctaa atctccaaca ggggcgagcc aagttatggt tcatattgtc agcaatgaaa
    42721 atttacaagt caagggagaa ttgtctgagt acaatctagc caacctttct gtaggtcaag
    42781 aagtaagctt tacttctaaa gtgtatcctg ataaaaaatg gactgggaaa ttaagctata
    42841 tttctgacta tcctaaaaac aatggtgaag cagctagtcc agcagccggg aataatacag
    42901 gttctaaata cccttatact attgatgtga caggcgaggt tggtgatttg aaacaaggtt
    42961 tttctgtcaa cattgaggtt aaaagcaaaa ctaaggctat tcttgttcct gttagcagtc
    43021 tagtaatgga tgatagtaaa aattatgtct ggattgtgga tgaacaacaa aaggctaaaa
    43081 aagttgaggt ttcattggga aatgctgacg cagaaaatca agaaatcact tctggtttaa
    43141 cgaacggtgc taaggtcatc agtaatccaa catcttcctt ggaagaagga aaagaggtga
    43201 aggctgatga agcaactaat tagtctaaaa aatatcttca gaagttaccg taatggtgac
    43261 caagaactgc aggttctcaa aaatatcaat ctagaagtga atgagggtga atttgtagcc
    43321 atcatgggac catctgggtc tggtaagtcc actctgatga atacgattgg catgttggat
    43381 acaccaacca gtggagaata ttatcttgaa ggtcaagaag tggctgggct gggtgaaaaa
    43441 caactagcta aggtccgtaa ccaacaaatc ggttttgtct ttcagcagtt ctttcttcta
    43501 tcgaagctca atgctctgca aaatgtagaa ttgcccttga tttacgcagg agtttcgtct
    43561 tcaaaacgtc gcaagttggc tgaggaatat ttagacaagg ttgaattgac agaacgtagt
    43621 caccatttac cttcagaatt atctggtggt caaaagcaac gtgtagccat tgcgcgtgcc
    43681 ttggtaaaca atccttctat tatcctagcg gatgaaccga caggagcctt ggataccaaa
    43741 acaggtaacc aaattatgca attattggtt gatttgaata aagaaggaaa aaccattatc
    43801 atggtaacgc atgagcctga gattgctgcc tatgccaaac gtcagattgt cattcgggat
    43861 ggggtcattt cgtctgacag tgctcagtta ggaaaggagg aaaactaaga tgcagaatct
    43921 gaaatttgcc ttttcatcta tcatggctca caagatgcgt tctttgctta ctatgattgg
    43981 gattattatc ggtgtttcat cagttgttgt gattatggct ttgggtgatt ccctatctcg
    44041 tcaagtcaat aaagatatga ctaaatctca gaaaaatatt agcgtctttt tttctcctaa
    44101 aaaaagtaaa gacgggtctt ttactcagaa acaatcagct tttacggttt ctggaaagga
    44161 agaggaagtt cctgttgaac cgccaaaacc gcaagaatcc tgggtccaag aggcagctaa
    44221 actgaaggga gtggatagtt actatgtaac caattcaacg aatgccatct tgacctatca
    44281 agataaaaag gttgagaatg ctaatttgac aggtggaaac agaacttaca tggacgctgt
    44341 taagaatgaa attattgcag gtcgtagtct gagagagcaa gatttcaaag agtttgcaag
    44401 tgtcattttg ctagatgagg aattgtccat tagtttattt gaatctcctc aagaggctat
    44461 taacaaggtt gtagaagtca atggatttag ttaccgggtc attggggttt atactagtcc
    44521 ggaggctaaa agatcaaaaa tatatgggtt tggtggcttg cctattacta ccaatatctc
    44581 ccttgctgcg aattttaatg tagatgaaat agctaatatt gtctttcgag tgaatgatac
    44641 cagtttaacc ccaactctgg gtccagaact ggcacgaaaa atgacagagc ttgcaggctt
    44701 acaacaggga gaataccagg tggcagatga gtccgttgta tttgcagaaa ttcaacaatc
    44761 gtttagtttt atgacgacga ttattagttc catcgcaggg atttctctct ttgttggagg
    44821 aactggtgtc atgaacatca tgctggtttc ggtgacagag cgcactcgtg agattggtct
    44881 tcgtaaggct ttgggcgcaa cacgtgccaa tattttaatt cagtttttga ttgaatccat
    44941 gattttgacc ttgttaggtg gcttaattgg cttgacaatt gcaagtggtt taactgcctt
    45001 agcaggtttg ttactgcaag gtttaataga aggtatagaa gttggagtat caatcccagt
    45061 tgccctattt agtcttgcag tttcggctag tgttggtatg atttttggag tcttgccagc
    45121 caacaaggca tcgaaacttg atccaattga agcccttcgt tatgaatgag atcaacaaga
    45181 tggacactcg tctatcttgt ttttgtatgg atttccctat cgaaattcat taaaaatgtg
    45241 atataatgaa gtgttagaaa aacaggtttc atttgcctgg aaaggaaaaa ttatgtctga
    45301 aaaaaatttt tatattacaa cgccgattta ctatccatct gggaaacttc atatcggttc
    45361 tgcctacaca actatcgcat gtgatgtcct agcacgttac aaacgcctga tgggctacga
    45421 tgtattttat ctgacaggtc ttgatgaaca tggtcagaaa atccagcaga aagcggaaga
    45481 agctggtatt acacctcaag cctatgttga tggaatggcg gttggagtta aagaactctg
    45541 gcaattacta gatatctcat acgataaatt tatccgtaca actgatgact accatgaaaa
    45601 agttgttgca caggtctttg aacgcttact tgctcaagat gatatctact tgggtgaata
    45661 ctctggttgg tattcagtat cagacgaaga attctttaca gaaagccagc tggcagaagt
    45721 tttccgtgat gaagctggaa atgtgactgg tggtattgct ccatcaggtc atgaggttga
    45781 atgggtttct gaagaatcat acttccttcg ccttagcaaa taccaagacc gtttggtcga
    45841 atttttcaaa gctcatcctg aatttatcac gccagatggt cgccttaatg aaatgctacg
    45901 caacttcatc gagccaggtt tggaagattt ggcggtatct cgtacaacct ttacatgggg
    45961 agtgcctgtc ccatcaaatc caaaacacgt tgtctacgtt tggattgatg cccttcttaa
    46021 ctatgcgaca gctcttggct acgctcaaga cgaacatggt aactttgaca agttctggaa
    46081 tggaacagtc ttccatatgg taggaaaaga tatccttcgc ttccactcta tctactggcc
    46141 aatccttctt atgatgttgg atgttaaatt acctgatcgt ttgattgccc atggttggtt
    46201 tgtcatgaaa gacggaaaaa tgtctaagtc aaaagggaat gtcgtttacc ctgaaatgtt
    46261 ggtagagcgt tatggactag atccacttcg ttactacctc atgcgtaacc ttccagttgg
    46321 ttcagacgga acctttactc ctgaagacta tgtcggccgt atcaactatg aattggctaa
    46381 tgaccttggg aacctcctta accgtacggt ttccatgatt aataagtact ttgatggaca
    46441 aatccctgcc tatgtagaag gtgtgactga atttgatcat gttcttgctg aggttgcaga
    46501 acaatcaatc gcagacttcc atacacacat ggaagcagtt gactatccac gtgcgcttga
    46561 agcagtctgg actctgatct ctcgtaccaa taaatacatc gatgagactg caccatgggt
    46621 cttggacaag gatgaagctc ttcgtgacca attggcaagt gtcatgagcc acttggcagc
    46681 cagcattcgt gtagttgctc acttgattga accatttatg atggaaacta gtcgtgcagt
    46741 tttgactcaa cttggtttgg aagaagtttc tagtcttgaa aacttgagtt tggctgactt
    46801 cccagcagat gtgactgtag ttgccaaagg aacacctatc tttccacgtc taaatatgga
    46861 agaagaaatc gcctatatca aggaacaaat ggaaggcaat aaaccagcag tcgaaaaaga
    46921 atggaatccg gacgaagttg agctcaaact aaacaaggat gaaatcaagt ttgaagactt
    46981 tgacaaggtt gaaatccgtg tcgcagaagt caaagaagtg tctaaagtag aaggttcaga
    47041 taagttgctt caattccgct tggatgctgg tgatggagaa gatcgtcaga ttctttcagg
    47101 aattgcaaaa tactatccaa atgaacaaga attggtcggc aagaaagttc aaatcgttgc
    47161 taacctcaaa ccacgtaaaa tgatgaaaaa atatgtcagc cagggtatga ttctctcagc
    47221 tgaacatgat ggcaaattaa cccttctcac agttgatcca gctgtaccaa atggaagtgt
    47281 gattgggtaa aagtagacag gactagttca ggctagttct gtttttttat ttatactcaa
    47341 tgaaaatcaa agagcaaact aggaagctag ccgcgggttg atcaaagcac tgctttgagg
    47401 ttgtagatga aactgacgaa gtcagctcaa agcactgctt tgaggttgta gatgaaactg
    47461 a
//
LOCUS       DAVKUR010000011        44725 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKUR010000011 DAVKUR010000000
VERSION     DAVKUR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.011"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VW749_000701"
     CDS             complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VW749_000701"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0174782.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VW749_000702"
     CDS             complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VW749_000702"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0174783.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7816..7886
                     /locus_tag="VW749_000703"
     tRNA            7816..7886
                     /locus_tag="VW749_000703"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7848..7850,aa:Cys,seq:gca)
     gene            complement(8084..9415)
                     /locus_tag="VW749_000704"
     CDS             complement(8084..9415)
                     /locus_tag="VW749_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0174784.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VW749_000705"
     CDS             complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VW749_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0174785.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10507..10695)
                     /locus_tag="VW749_000706"
     CDS             complement(10507..10695)
                     /locus_tag="VW749_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0174786.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VW749_000707"
     CDS             complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VW749_000707"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0174787.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11995..12225)
                     /locus_tag="VW749_000708"
     CDS             complement(11995..12225)
                     /locus_tag="VW749_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0174788.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12283..13320)
                     /locus_tag="VW749_000709"
     CDS             complement(12283..13320)
                     /locus_tag="VW749_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0174789.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VW749_000710"
     CDS             complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VW749_000710"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0174790.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VW749_000711"
     CDS             complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VW749_000711"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0174791.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14386..15378)
                     /locus_tag="VW749_000712"
     CDS             complement(14386..15378)
                     /locus_tag="VW749_000712"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0174792.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15490..16173)
                     /locus_tag="VW749_000713"
     CDS             complement(15490..16173)
                     /locus_tag="VW749_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0174793.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16229..16969)
                     /locus_tag="VW749_000714"
     CDS             complement(16229..16969)
                     /locus_tag="VW749_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0174794.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17003..17281
                     /locus_tag="VW749_000715"
     CDS             17003..17281
                     /locus_tag="VW749_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0174795.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17359..18285
                     /gene="yidC"
                     /locus_tag="VW749_000716"
     CDS             17359..18285
                     /gene="yidC"
                     /locus_tag="VW749_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0174796.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVHEELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VW749_000717"
     CDS             complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VW749_000717"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0174797.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19280..20530)
                     /locus_tag="VW749_000718"
     CDS             complement(19280..20530)
                     /locus_tag="VW749_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0174798.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VW749_000719"
     CDS             complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VW749_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0174799.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21691..22632)
                     /locus_tag="VW749_000720"
     CDS             complement(21691..22632)
                     /locus_tag="VW749_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0174800.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(22622..23878)
                     /locus_tag="VW749_000721"
     CDS             complement(22622..23878)
                     /locus_tag="VW749_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0174801.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23880..24542)
                     /locus_tag="VW749_000722"
     CDS             complement(23880..24542)
                     /locus_tag="VW749_000722"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0174802.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24505..25161)
                     /locus_tag="VW749_000723"
     CDS             complement(24505..25161)
                     /locus_tag="VW749_000723"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0174803.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VW749_000724"
     CDS             complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VW749_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0174804.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFFNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETHKKVSKKIPK"
     gene            complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VW749_000725"
     CDS             complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VW749_000725"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0174805.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFACLADALKGQGL"
     gene            complement(27055..27363)
                     /locus_tag="VW749_000726"
     CDS             complement(27055..27363)
                     /locus_tag="VW749_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174806.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(27356..27997)
                     /locus_tag="VW749_000727"
     CDS             complement(27356..27997)
                     /locus_tag="VW749_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174807.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(27999..30029)
                     /locus_tag="VW749_000728"
     CDS             complement(27999..30029)
                     /locus_tag="VW749_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0174808.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREKVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSI
                     LGLGILWYQGALFMATVQLVIIALLLYGLILAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQYSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30298..31197)
                     /locus_tag="VW749_000729"
     CDS             complement(30298..31197)
                     /locus_tag="VW749_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0174809.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VW749_000730"
     CDS             complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VW749_000730"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0174810.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(31829..32602)
                     /locus_tag="VW749_000731"
     CDS             complement(31829..32602)
                     /locus_tag="VW749_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0174811.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(32907..33800)
                     /locus_tag="VW749_000732"
     CDS             complement(32907..33800)
                     /locus_tag="VW749_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0174812.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VW749_000733"
     CDS             complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VW749_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0174813.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(34363..35577)
                     /locus_tag="VW749_000734"
     CDS             complement(34363..35577)
                     /locus_tag="VW749_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0174814.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(35733..36027)
                     /locus_tag="VW749_000735"
                     /pseudo
     CDS             complement(35733..36027)
                     /locus_tag="VW749_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36189..36641
                     /locus_tag="VW749_000736"
     CDS             36189..36641
                     /locus_tag="VW749_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0174815.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(36676..38064)
                     /locus_tag="VW749_000737"
     CDS             complement(36676..38064)
                     /locus_tag="VW749_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0174816.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            38130..39092
                     /locus_tag="VW749_000738"
     CDS             38130..39092
                     /locus_tag="VW749_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0174817.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(39121..39279)
                     /locus_tag="VW749_000739"
     CDS             complement(39121..39279)
                     /locus_tag="VW749_000739"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174818.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     NHTYGKAT"
     gene            complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VW749_000740"
     CDS             complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VW749_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0174819.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(40778..41377)
                     /locus_tag="VW749_000741"
     CDS             complement(40778..41377)
                     /locus_tag="VW749_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0174820.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(41379..42476)
                     /locus_tag="VW749_000742"
     CDS             complement(41379..42476)
                     /locus_tag="VW749_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0174821.1"
                     /translation="MLERLKSIHYMFWVSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     EAMTSMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(42476..43213)
                     /locus_tag="VW749_000743"
     CDS             complement(42476..43213)
                     /locus_tag="VW749_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174822.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(43215..44099)
                     /locus_tag="VW749_000744"
     CDS             complement(43215..44099)
                     /locus_tag="VW749_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174823.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(44086..44280)
                     /locus_tag="VW749_000745"
     CDS             complement(44086..44280)
                     /locus_tag="VW749_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174824.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(44277..44483)
                     /locus_tag="VW749_000746"
     CDS             complement(44277..44483)
                     /locus_tag="VW749_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174825.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        12748 a        10448 c         8514 g        13015 t
ORIGIN      
        1 tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaaccctc
       61 gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac
      121 aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc
      181 ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat
      241 gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct taccacggat
      301 agctgcgtca gtaaggacac gagttgtttc ctggaaggaa gccgctgaca agaaactgtt
      361 tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc
      421 acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc
      481 catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac
      541 cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac
      601 ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg
      661 ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg
      721 catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac
      781 tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt
      841 aataaccgct tcccctttag gattgcgggc ttcaaagatt tcttggacac gaggaagacc
      901 ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg
      961 tgtaccaggt tccccgatag attgggcagc gattgtacca actgcttcac caacttcaac
     1021 cgcatcacca gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt
     1081 acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc
     1141 cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt
     1201 aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt
     1261 tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat
     1321 gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt
     1381 aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac
     1441 cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc
     1501 agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc
     1561 agagtccatc atcataacga ttgggttctt aggatcttga ttagcaatca agcgtttctc
     1621 aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt
     1681 gatcatacca cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat
     1741 gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag
     1801 agttgagtgg tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt
     1861 acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct tgaatggagg
     1921 gttgagctca agattgctga tagcttcctt gatagctcca ccaagtggca agaagtattt
     1981 agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg gtagcccctc
     2041 tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg
     2101 ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg
     2161 aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc
     2221 accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga
     2281 tggagtaact accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag
     2341 gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc
     2401 gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc
     2461 aattaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa
     2521 aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg
     2581 ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg
     2641 catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac attggtacat
     2701 cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag
     2761 caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg atttcaatgg
     2821 acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcatcaac
     2881 tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat ttaactcaag
     2941 caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga
     3001 tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg
     3061 aaggatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac
     3121 atccaaacga cggatggctt tgacacgttt ttgtccagta gctgttttca attcttcttt
     3181 gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc
     3241 acccatcttg gcaacaaatg aaccataacc atattcacgc aagcgctctc ggtattcgcg
     3301 ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc
     3361 cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg
     3421 gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt cgatatgtcc
     3481 catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat
     3541 tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc
     3601 aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat aattgattgt
     3661 ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt
     3721 gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag
     3781 tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca
     3841 gcttcttcag cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca
     3901 aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact
     3961 tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa ttctttgaca
     4021 agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct
     4081 tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg
     4141 acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca
     4201 ccaaactgag ctttacctcc gagtggttgt tgggtaacag ttgagtaagg tccgactgaa
     4261 cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga tcatgtacat gactccaaca
     4321 gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt cttggcatcg
     4381 ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag
     4441 actggtgtcg caatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata
     4501 acctgaccga tattcatacg tgatggcacc ccaagtgggt tcaacatgat gtcgactgga
     4561 gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg
     4621 tttccatgac gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa
     4681 acacgaacca acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc
     4741 ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact
     4801 tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc
     4861 tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata
     4921 cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg
     4981 cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg
     5041 tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg
     5101 aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct
     5161 ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact
     5221 tttacgagag tgcgttggtt gtaagcagta cctgagtttg aacgacggaa tttttggatg
     5281 tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa
     5341 gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat
     5401 tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc
     5461 atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga
     5581 tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct
     5641 tcattcagac gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac
     5701 caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga
     5761 acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta
     5821 ggtccttcag gtgtttcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc
     5881 acttcatatc cggcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt
     5941 ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa
     6001 ccaaagaatt ctttaactgc agctgttaca ggacggatat tgataatttg ttgtggtgtc
     6061 aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt
     6121 cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg
     6181 tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca
     6241 gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg
     6301 atcgttacga cgcgatctgg atcagttgga gcaacaacct tgaatttttg aagaacaaca
     6361 ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc
     6421 aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag
     6481 atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag caaacgtgtt
     6541 ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc atagcgacgt
     6601 gggtcaaaga agcgagccac aagcaagcta cgtgagcttt cagctgtctt aggctcacct
     6661 ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc
     6721 ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa gatatcaaag
     6781 atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga
     6841 gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct
     6901 ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg
     6961 ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg
     7021 atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc
     7081 ttgatttcgc ctgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag
     7141 ctagcatcgt ggatacgagc ttcttctagc gtgtattttg gttccttgat ttcatatcca
     7201 acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact
     7261 tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt
     7321 ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat
     7381 tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat
     7441 caggcttttc taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat
     7501 tttcagaatc tttaagcctc tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag
     7561 agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat
     7621 ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc tagatttttc
     7681 aaggggtttc agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg
     7741 aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat
     7801 aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat
     7861 cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca
     7921 gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa taaatacgta taactttaaa
     7981 aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca
     8041 attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt
     8101 ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat
     8161 cattggttaa gataaactgt ttgttttggc tgaccaattc atagctgagt ttctcagtcg
     8221 ttggaatagt tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt
     8281 ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt
     8341 aggtatcctc gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt
     8401 caccaacaat ttcctctaag aggtcttcca aagtcaccaa accagccata ccaccgtatt
     8461 catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca
     8521 caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa acaatattgt
     8581 caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat
     8641 tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga
     8701 taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga ggcaccataa
     8761 cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag
     8821 catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatctttt
     8881 catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta
     8941 aaagccaaac aaaaggactg actagttttc cgatcccaat gataatcggc gctgtacgaa
     9001 ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga
     9061 tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc
     9121 cattcccaag ccaagaggca atcacacgtc ctagagtatt agttaaactc gcccctgata
     9181 agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta
     9241 gtaccttcag caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg
     9301 cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca
     9361 agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc
     9421 ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca atacatatta
     9481 ttttttctta ccgtaacttc tcaaagtaac ttccatctct ctcccaaaac tggaagttag
     9541 ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac tagtaaaaag
     9601 aactcctaca tccataagtg acataggagt ttaggcttat cttttactga gttacagtta
     9661 cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga
     9721 attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct
     9781 cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt
     9841 tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg
     9901 cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca
     9961 aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc
    10021 cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag
    10081 tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg
    10141 gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct
    10201 tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca
    10261 gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac
    10321 taggagcttc agacgcttgt tttttctgac taagattggt tttgggacta ttaggtgccg
    10381 acggcatctg cttgatataa tagctccctg tagacaaaag caataacact agcagtccga
    10441 ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc
    10501 tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat
    10561 agcccatgga tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag
    10621 agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct
    10681 tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg
    10741 ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag
    10801 tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga aggtcagttg
    10861 aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa
    10921 tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa
    10981 ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct
    11041 gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt
    11101 ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa
    11161 gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac
    11221 caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtct tggactacat
    11281 tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac
    11341 ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac
    11401 gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct
    11461 gcgttgcacc aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct
    11521 tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc agacctttca
    11581 aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat
    11641 gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat
    11701 acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt
    11761 cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat
    11821 ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg
    11881 ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat
    11941 tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt gatttcataa
    12001 taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat
    12061 gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg tattatcatc
    12121 tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa aactcacata
    12181 aataaagaac atatgactac ttagagtgaa taataattga accatttgac tattatacca
    12241 tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa
    12301 gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt
    12361 tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc
    12421 ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc
    12481 tacaaccttc ttatcaatgc ctccaatgtc tcccacatta ccatcgcggt caatggtacc
    12541 tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc
    12601 tagactaaac atgagaccag cacttgggcc gccaatacca gctgttgaaa agctaattgg
    12661 gacattgctg attacctctg tacgatcaat caagccgatt ccaattccat ttttgccatt
    12721 ttccaaggtg ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac
    12781 cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc
    12841 aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt
    12901 tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga tatccttacc
    12961 agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt
    13021 gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc
    13081 tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt gaacaccaac
    13141 cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttactt taaggacttg
    13201 gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca ctacaaatgc
    13261 caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct tttttttcat
    13321 ttcttatttc ctccaaaata ctctcgggaa catggcaggc aatatcctga ccaaacttca
    13381 aaagctctcg aacacctgat gaactgatat agagatgttc aggccggcta tgtaaataaa
    13441 tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactagct tcatattgca
    13501 aatccgccgc attcctcaac ccccgtacta ggaaagtagc ccccagtctt tttgcaacat
    13561 cgaccaccaa ttcatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct
    13621 tttctagccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa
    13681 aaatacccac ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc
    13741 catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc
    13801 accttactaa ttccataaat cttttccttc cagataccca gacaggcaat ctcttctgga
    13861 agttcaacgg ccttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc
    13921 ttagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa
    13981 acgaggtcaa attccccaga tacctgttcc aatgccctct ctgcatccat cttgaggagt
    14041 tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta
    14101 cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa
    14161 ccaccactac ctgcataaag gtccaagact cgtccccctt caaagtaggg accaatcatg
    14221 ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg ttgtcttgcc ttctagtgtc
    14281 ttgaggggac gtcccccata gattcctgat acgattttca tactgtttat tataccaaat
    14341 tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc
    14401 gtaagtatcg cgtacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt
    14461 gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa
    14521 taggccattc aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat
    14581 ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa
    14641 ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt
    14701 ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc
    14761 tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt
    14821 ttcacgttct ttcgatgtca agtctggata gcgttctacc aattcttctg tatggataaa
    14881 ggtgatttgt tttggcaaga tagactcgat gtcatagcga gcttcaacag ctagctcagt
    14941 caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt
    15001 accatttggg ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc
    15061 caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc
    15121 aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata
    15181 agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt
    15241 gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag
    15301 cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg
    15361 gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat
    15421 ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc
    15481 atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa
    15541 atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga
    15601 ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa
    15661 aaccatggct acactaatca tataatcaaa gaagccacta gccaagaaaa tattgactac
    15721 catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc
    15781 tttcttggta aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa
    15841 ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt
    15901 taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct
    15961 actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc
    16021 ctgcatcaac aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa
    16081 agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag
    16141 acctgcacgg tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt
    16201 tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg
    16261 caactgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg
    16321 cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat
    16381 tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca
    16441 ctgggatagc taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg
    16501 gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg
    16561 acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc
    16621 ctacattacc gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag
    16681 cttgtcctac ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg
    16741 ccaaatctag caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat
    16801 ctcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt
    16861 caaacaagtg ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt
    16921 tcttggcatt ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat
    16981 aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca
    17041 gggagtcggc tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg
    17101 tcgagtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc
    17161 tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag
    17221 ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta
    17281 ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt
    17341 aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cactctcagc tatgggagcg
    17401 gctatgttgc ttgtcttgac tggttgtgtc aatgtcgata aaaccacagg tcagccaaca
    17461 ggatttattt ggaataccat cggagcccct atggctgaag ctatcaagta cttcgctact
    17521 gataaaggtc taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt
    17581 atcttgccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac
    17641 gccctcaagc acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa
    17701 gaaaaactcg aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg
    17761 tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac
    17821 tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt
    17881 tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt
    17941 tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg
    18001 agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg
    18061 gttgtcggtg gtttcatgat gattctccag caatttatcg tcaactatat cgttcgtcca
    18121 aaacttcgca aaaaagtcca tgaagaactg gcaaagaacc catcaaaagc aagtgctttc
    18181 tcaacaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat tacaagcaag
    18241 aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta
    18301 gctgatttgc taagtctttt tgcaagtcaa aagcccgatg tttccatcag gcttcttttc
    18361 tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg
    18421 ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt
    18481 tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt
    18541 ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct
    18601 ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa
    18661 gccaagatat ttttattggt ttggctagtg acaatcttgt gctgttcttc gttgatttcc
    18721 ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa
    18781 cgcggtttat tacggaaagg aagagcacag gtgtccaagg tacagtggat tccttgttcc
    18841 ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg
    18901 actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca
    18961 tcatctaccg tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg
    19021 caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca
    19081 tctactgacc caaagctttc tgtcgaatgc accatccctg tcacttgtcc ataatcaatt
    19141 gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga
    19201 cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca
    19261 ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt
    19321 cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt
    19381 ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat
    19441 catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt
    19501 tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat
    19561 gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg
    19621 ctgaggcatc tacacctaga taggtacggt aggtttcctt cttatgagtg actcttgtga
    19681 ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac
    19741 caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg
    19801 cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga
    19861 taaagtctaa cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac
    19921 gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag gagtgaagcc
    19981 caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg
    20041 tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc
    20101 ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt
    20161 caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt
    20221 ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat
    20281 ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa
    20341 ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt
    20401 tccacgaaaa agcttggttg acagctcttg ccttctcacg aatccccttc tcatcataca
    20461 agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg
    20521 gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa
    20581 cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg
    20641 cttggttctt gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt
    20701 cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact
    20761 cgcgcaagag actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa
    20821 tcaagacacg gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt
    20881 caccacttga acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt
    20941 cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca
    21001 cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa
    21061 taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat
    21121 aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt
    21181 ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca
    21241 ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt
    21301 ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt
    21361 tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt
    21421 tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg
    21481 tcgctggtgg ttcaaaacac tgctttgaga ttgtcgatag aactgacaaa ccctgtaata
    21541 tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga
    21601 gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta
    21661 tcctaaaaaa tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg
    21721 attatccata gcgaagattt tattggacat ctctccttta tccaccaaag ccagagctgt
    21781 tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat
    21841 aatacgtgga cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg
    21901 acgaagcaaa acgacttctt ccttggtatc gtcgatgccg agttccataa ctgtcttggt
    21961 aatttcgcta tcaatgagag cgatatgtcc aagaagattg cctcgcactg tgtactctgt
    22021 ctggtctggc cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata
    22081 gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat
    22141 ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg
    22201 ataggagtag aattccttat catacttggt gtagagattt cggacaatcc gttgccagac
    22261 aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac
    22321 tggtgacttg accttgaaat cagctgggtc attgggttca ccagcttgag gcaggcggag
    22381 agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac
    22441 aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc
    22501 aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg
    22561 cctcaggtca gctgatttga ttaggtaaaa gccttcaaat aactcatctt ttttcatgtg
    22621 actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac
    22681 cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata
    22741 attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac
    22801 caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct
    22861 tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac
    22921 ttggtcctgc aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc
    22981 ggacgatttc tgagtagaga ccttctgtcg gaacaaacaa gattccaaaa ttggttgtcc
    23041 gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg cttgctagga
    23101 gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc
    23161 ggtaataatc tgccagtgga aacttagagt caattggaag atagacgtat tcttggtcgc
    23221 cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt
    23281 attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt
    23341 ctcccagaat ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac
    23401 gggcaactgt ctgcatttct ccaagaccac gattgacaga ctccagttgt ttagaaactg
    23461 tctcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct
    23521 ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg
    23581 tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg gtcaggcctt
    23641 ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac agccacttcc aaatcttttt
    23701 ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat
    23761 gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc
    23821 aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa ctttccatcc
    23881 tacctcctat ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact
    23941 tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc
    24001 aactcatact tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga
    24061 tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctggacaata agtaatcaag
    24121 ttttgcccat cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc
    24181 agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc
    24241 tgagcctgag gattttgttc aaagatggtt aagagagcca attccaaatc ggtatcatct
    24301 ttttctggtc gtgcttggac aaaatgctgg gcacgttttt gaatcacctg tcgctcttct
    24361 tcggtcacag aatcaaaatc cccaactgct agagcaagag gcaagtcttc ttccaagacc
    24421 cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg
    24481 tctccgcctg caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc
    24541 attgacatct cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt
    24601 agcttgggca atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc
    24661 tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg gcagaaaggc
    24721 ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac
    24781 gtgcttgatg gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag
    24841 tgaacgaatt ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat
    24901 gatgtctgca cctgcgcgcg caaagtcttc cagatggtgt tcaggattcg ccaccatcaa
    24961 gtgacagtca aagaccatct tactatgtgg acgaagtgct tcaaccacac cggcaccaaa
    25021 actgatttgt ggcacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt
    25081 tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg
    25141 agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt
    25201 tatgggtttc tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga
    25261 aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat
    25321 gggtacaagt acgaaactta caatctcggc tgacagtagc aatctctggg aaagcctgat
    25381 tgaggtcttc agcccttgat acttcatagt ccagagatga aaagcctggt gtgtctgcga
    25441 ttttaccccc attgaggttg aaaaaactaa cagctcgagt agtatggcgc ccacgaccca
    25501 gactgtctga gatttctcct gtttcaagat tgaggtctgg tgcgattttg ttgagaagag
    25561 ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca
    25621 ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa
    25681 aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga
    25741 tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt
    25801 ccttgacgga catgattact acagcttgat cgatattgac aataggcgga cgaaccagac
    25861 tgtttttccg ttcgtgaatt tttaggatat agccttctga attttcctcg gcagagaaat
    25921 ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg
    25981 tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt
    26041 gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagacaggc aaattctgcc
    26101 aagctgagag cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc
    26161 agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc
    26221 ttacggcgat gggtaaaact agccttggaa accttaaaga agaagttctc atcttccact
    26281 gctacagctg gctctggacg gcgcaccatt ttcaagatgg ctgaatccac atttggcgct
    26341 ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg
    26401 gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact
    26461 tctttctgca tcatgaccac aaactcacta aaaggaatcc cactctcaat caagtgcatg
    26521 agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggttagga
    26581 tttttaaaat tttggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactaca
    26641 gtcacattat caaaatcacg cagggtatct gccaaaattg gcaccaaacg gtggtcaatc
    26701 tcaaaagcca tgacttgggc tgcacgctca gccagaaact ccgtcaaggc accaatacct
    26761 ggcccgattt cgatgacatt gacctggtca tcaatttcag ccgtatccac aattttttga
    26821 aggatattgg tatccgtcag gaaattttgc ccgaaggact ttttaaaggt aaaaccgtga
    26881 cgctccagca ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat
    26941 tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa
    27001 aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaaagt ggccttaaca
    27061 gttctctcga aacatgcgtt caaaaaaatc agcttcttga taacttcgat tttcgggtag
    27121 ggtcaaatcc acatcctcct ccacatcatc cactgtcagt tcaaccgtct gaggtaaatt
    27181 tttcaaacga taatgctttt gcctttgccc ttcaatacta gcaaaatcaa gcaaatagcc
    27241 atgtactcgg atttgaacca aaaggagatg attggtcata ttttccatga tgaggatatc
    27301 ttctaaacca cctctggcac taggataatc agatactctg cgaatacgga ttttttcaca
    27361 catgagcaag tttcctcata tcaatgattt catcagcctt attccagact aggggattat
    27421 gggtcgcaat gatgatcatt cgattttcat ctttcaaatc caccaagaga ttcataacct
    27481 cctctgaatt ttcaggatca agagctgctg ttggttcatc tgccaaaatc aagggtggat
    27541 ttttcaaaat agtcttagca agggcaactc gttgggcctc tcccccagat aaagtataaa
    27601 ttttttgttc taaatccaaa taccctagat taactttttc taaagccccc acttgccttt
    27661 ccaaacgttc tacttttgag attttctgac caacaaaacc caaatccaaa ttttctttga
    27721 ttgattggtt ttctaagagg ccaaaatttt gaaagagata gcccatctga tctcgaaaat
    27781 actcacgagt gggaatggtt tttaaatctt tcccctgata gagaaccctt cctccatcta
    27841 tcttttctag ctttcccaag atattcagca gcgtcgtctt tccgcttcca ctctttccga
    27901 ttaaggcata aaccttgccc ttctccagct tgagattcaa accagagaaa atcgcgcggt
    27961 cattaaattt cttttccaat ccttgaatat caatcatctt attttccttt caatactgcc
    28021 atgctaccag cttcttcttt tttgtcctgc cttactaaaa tcaagagggc gttaagcgta
    28081 aacaaagcta caactagagc gctaatcaaa ccatctcttg tcaaaatact agataggact
    28141 aggccaagca agagaactcc tccttgcgcc agtaaatact tgccatgaag ctcatagatt
    28201 gtcataccag caagacgttt aatcataagc tcccgtctga actgctcaaa atagagaaga
    28261 ttcatggaat caaataacaa gatagccgta gacagggtca aaatcgtccc aataaggaga
    28321 gagtaaaact ccacccgttt gtcatttagt accttggcaa aaaatagctg gctttttacc
    28381 aagtaagaaa ccttgtgata cagaccttgc tcttttagag ctgtgatgct gtctccatat
    28441 cgatctagtt tcaaggcact attagccgta gttccccaca acatccctgc aacaggtctt
    28501 gttccagtcg cttgcggcgt tagaactaca ataatcggat cttttaggta ctggcgtgtt
    28561 gtcttgtacc catcattata gaggaaacgt tcctgtcctg tttctgtaaa agctagcctt
    28621 acctgtggga agtagtgttt ctgactcgtc acttctacac tttcagatga aaagttttgc
    28681 aggtaatctg taaacaatcc ttggtagtag gcagactgct ctcgcaagct ctcaggcaag
    28741 atcagcccaa actctccctc agacaagttt tgcatcttgt ccataaactc tgaagaaacg
    28801 gtaatctttt cttctatcag atagcgtggt gagacataga taacattccc tgacggtgtg
    28861 tagtcactga gacgattacc atctaggtcc acttctgctc catctgagaa attgtcaaca
    28921 ttgctcataa tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa tgtctgccac
    28981 tcacgattat ccttacgcgt tccttcttca tcggcaaatg cactagacca accaaaggat
    29041 agacggtaac ggtctgagta ctggctccat ttattgctag ctctctccat ttcctgcatt
    29101 tcacggtagt ggggtaggag agctgtcgca ctcgatccga ccaccaatac agctaagagt
    29161 tgccccacca tcatcaatgt catcatacgt ttgagaggga gtttcccttt caatagatcc
    29221 accagactat tttcctgtaa accaagtaga tagacgacac ttagtaaggt agaaatccct
    29281 gccaagatca atccataaag tagaagagca atgatgacca gttgcaccgt tgccataaac
    29341 aaggcacctt gataccagag aatccccaat cccaaaatac tggataccag cactgagcag
    29401 ataagctgtc tcacatcttc taacactggt ctgagagcaa ctccaaacaa gctctcacca
    29461 gctattaagc gaatccctgc ctgacgaagg gatttgatcc gataaatcag ggtcagactc
    29521 ataaaggtca gcagaaaaat agctaaactc agtagcacca taggggtggc cgtcaatagt
    29581 aagactatcg aaaatggatc ttctccattc gaaacaaagc cttgatagcc aagttctttc
    29641 aaggtggtct gtaagctcac tccatccaaa cttcctgaca caatcaagta agaccctaat
    29701 aaatcactcg tttctgcact ctccttggag gaaatggtca gaccttctgg aagctctccc
    29761 tcaccataag tggcataggt aaagagtgtt tctccagctt catttggctc aacgattcga
    29821 cgggcgatga gactattatg ctctaccgcc aagtgactca aagcctctgt caccttttcg
    29881 cgactagcta ctggttgatt tatcatcatt cctgtcacat caacagaagg atagttacca
    29941 aataaaatct cttctcgatg gtcaacggaa gttatcacca tataaagcga taccaatacc
    30001 attgaaatca aaataaataa acgtttcatc atttcctcca aaaagttact tggtcactta
    30061 gtgagaaggt gaccacagtc actgcgatgt taagaagctt attaagttct ttctgctagc
    30121 aacatcttca aatatattat atccgttttt tcaagaacta tcaaggacat caatgtcctt
    30181 aaaatctaac tatttcatat tatttttagc ttatatctaa aaaaacagtt ctaaagacga
    30241 actttagaac tgttttgata cgaggacaag gacatttttg tcactgattc actatgttta
    30301 taaatatttt ttgacatcct cttgccattc ctctgtcaat ttctttacta gaaatccatc
    30361 tccaattagc ttcgcaaatg ttttagaaga ctgataaaat gattcagcta aactaaaatc
    30421 tctttctact cttaatgctt gcttccacaa aaacataaat acaagaggtt tcttttgata
    30481 atcttgagtt ttatccataa tttcttgtaa acacgataga taatcattaa aacaatcagt
    30541 tactcctacc ttttcaagac aacacattcc tgaaataaga gtatctctaa ttataaagta
    30601 attctctatt tgagttacct tcttctgttc caaaagaaag agcattagct tttcgatttg
    30661 atttataaat ttggcaagat cttttctaat gagcatttga taaaaaaaca aacgaatcaa
    30721 caacatatca tttgttgaat aaacttcttt ttctatgatc tgagacatat gttcctcaag
    30781 tattaactct gcatattcag gccttctagt tctagaagta tccaaacacg cctgcaatac
    30841 ttcacatgct aattgttctt ctttaggaag attatcaaag tatgttttat aaatctcttc
    30901 caaacacgct tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat
    30961 ctggtatttc aattctaaat aagcagaagg aagagctgaa aaatccggca taaggctata
    31021 aactggaact cctagccggc gagcaatata gtctaacttg ggcaaactcg gttgcgaagc
    31081 tccactttca attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc
    31141 tggacgacta attccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag
    31201 acgcctcctc ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggtca
    31261 catctttcct actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac
    31321 aactctaggc gtttgaggag ttgcttgccg ttagaatagc cgattcggag agtctctccg
    31381 agatattctc tacgcttaca gctgtctgcc cctgctagaa aaccaaggcg aatcaagtcg
    31441 ctacgactaa tgtcaaactg actctcatgt tcaaattgtt ctgtcacctg agctagagcc
    31501 gttttcaggt cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac
    31561 ttgggaacag cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccatcatg
    31621 atcatgcgcc gaatccgttc cccattaaaa tctgggtctg taaagacaat gactccatga
    31681 cgttggtgca ggcgctgaat ccgctctata tcctgagcat tgatggcaga acctcgagtc
    31741 tcataggtct ccacatcgaa ataacgtttg agattgaccg tatcatcacg cccttcaacc
    31801 acgataactt gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg
    31861 catttgcagt cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa
    31921 agtcgaccac atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg
    31981 ctaagtaagg cgcatctgtt tccaccaaca tcttgtccaa aggtaactct ttagctgctt
    32041 cttggaggtc agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa
    32101 gatccacaaa cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac
    32161 gaggaccaac gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat
    32221 ggacaacaaa aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct
    32281 cctgcacctc tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca
    32341 caaccttgga atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac
    32401 cagcttctgt aggatgccaa ccaatagtcg catagagctg ctcatactca tctaccaact
    32461 ccaaggcatg ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca
    32521 tctcagcagc caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt
    32581 gtgtatgtgt atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa
    32641 aaagaggagg ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct
    32701 gctatctttt ctatccgata ttgcccatct cctattccac agttagagac agaagagatt
    32761 ggctacattg atagaatatt cctattcagc taaagtatgt gattatcttg ggttctcact
    32821 tttctcaccc atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa
    32881 gtagagaata gaattttcta gctgttctat tttctacgtc tagtctttct tcctagcaaa
    32941 gcaaaaccac ttgttgccac cactagacca agactagcaa gtgctgcact tgatgctgaa
    33001 cctgtgttag gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct
    33061 gcagttgctt gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta
    33121 ggaactgtaa ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc
    33181 atagttttcg cattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct
    33241 aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc
    33301 ttggctgctt tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa
    33361 gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg atccacccgc ctggctacca
    33421 ccgccttcat tcgcattagc atctgagctt ccagtattgc ctcccttatc tccacctggt
    33481 gtattttcta gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat
    33541 tgttgaactg tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt
    33601 gctgtaccat ctccagctac attgattgtc gctccgtcta atgctgaacc atttgcttgt
    33661 aaaatagcaa ccttaacttt ttcttcatct gttaaatgag ttatatcttt tacatctact
    33721 ctttgagcag gtgctttaac agttgatttt tcagcagtca gtttagtgct atcttgtgct
    33781 tttggatctt gtgctaccaa ttgatttcct ggaattgtaa tagctgaacc atctttaaag
    33841 acgattgttg ctgtaccatc tccacctact tcaactttat agtaaaataa aataataaca
    33901 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa cagaggtgta
    33961 ctattctagt ttcaatctac tgtaacatcg cttccgaatc cgtttgcatc tactgaactt
    34021 ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata gaattcgttt
    34081 ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata cgcgacgacc
    34141 atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa gtttacttgg
    34201 ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt ttagccggct
    34261 ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc acttttgtca
    34321 atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac gatactgttt
    34381 caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag gaaggtaaac
    34441 gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca agagaacctt
    34501 ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt acatattgcg
    34561 gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca aacctggaat
    34621 atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac caggaagaag
    34681 caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt gggccaaaac
    34741 gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc ccttaacatg
    34801 agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc ggtgggattt
    34861 tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca caggcgtatg
    34921 cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa tcaaatcgtt
    34981 ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg ctccagttgg
    35041 gttattggga ttgataagga caattgcctt ggtattggaa gtgatttttg acttgatatc
    35101 gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg catttcctcc
    35161 agctaggctg acagccgccg tccatagagg atagtctggc attggcacta agacctcatc
    35221 cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac catttccaag
    35281 gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact gcatgatggc
    35341 cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac gcgcattcat
    35401 aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg gatttcctgt
    35461 attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt ccaatacagg
    35521 accacggata tcataagcaa catgctctaa cttactagac ttgttatatt ctttcatctt
    35581 gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg cgacaagttt
    35641 actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg aggttaagaa
    35701 cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa acctagaaaa
    35761 aagcaagcct agaaaggagt cataaagaag attaaacatg aggaaaagcc cccatatcat
    35821 caagtaatcc caacgcccac ttcgttttgc aactagaaat aagattagat ggtagagtac
    35881 atgaaaaact aaaaatccaa taaaacttgg ataaagaagc ggtaccagac tctctaattg
    35941 acagatcatg atcacttcta ccaagactga aactaggata attccataat aaaggaaatt
    36001 tgatttttga aaagagtttt tcatcattct cccttccttc acttctttcc tgctatcctt
    36061 tcttttattt tatcatatat ttatatagag tttaagccct aatattcttt tgaaaaatac
    36121 tttttttgct ttacttctat agtgaaaagg tttacaatta tagtaagaaa atttcaggag
    36181 gtttcattat ggcacaacgt taccaaaata tcatggtcgc aatcgatggt tctaaggaag
    36241 cggacttggc ttttgtcaag ggagttcatt ctgctctacg aaacgacgct aaactcacca
    36301 tcgcacatgt cattgacaca cgcgctctcc aaagcgtatc cacctttgat gctgaagttt
    36361 acgaagaact ccaagtcgac gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag
    36421 atgctggggt agcagatgtt catatcgtca ttgaaatggg aaatccaaag accctgctag
    36481 cacgtactat tccagatgcc gaggaagtgg acctcatcct cgttggcgca actggtctca
    36541 acgcctttga acgcctcttg gtcggctctt catctgaata catactccgc catgctaagg
    36601 tcgatttgct ggttgtgaga gaacaagaaa aaaccttata atcacaaaga aaaggagccc
    36661 ctagctcctt tttgtttacg atttatttct ctctttatgg cgttcgtaag ccttgagctg
    36721 gcgctgcagt tcctttttaa tagcaggttc tggagcatat ttttcttccc aattatctgg
    36781 ttttaagatt ttatgggtca ctggatcaaa atgagccttg ccatctggaa aaattttccc
    36841 catattggcc tgatggacaa tatcaaaaat acgttctggg tccaccccca tcaagacaaa
    36901 actgccgtag gtgaagtaaa gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg
    36961 ctgagcaggt gtcttcttgg ctactttacc tgctgcctta tcaagggcct gatgaagttg
    37021 cgatacagct tgaccaaaat cttcttcaga aggactggct gatcgaacaa actccaccaa
    37081 ttcttctatt ttaaaaccag ccctatgggt tgcaccctct aaatcccaag ctcgaggttc
    37141 ttcttgggtt cgttcatcca tcatgtggtg gaaggtcttg accttattga aatgatagtc
    37201 acggctgaca aaaacttttt ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat
    37261 cccatcttgt tgattgctag tggtaatgtg cttggcagct tccttgacac tgctactacc
    37321 atttcccata gcgaccgaca taccgacgcc agccagcatt tcaaggtcat tatctgagtc
    37381 accaaaagcc atgacttggt tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc
    37441 ttctaattta gaatttccct gattgatgac atccgatgca aaaggattgc tacgtgtcaa
    37501 tttcaagtct tcaaaatcag ctgccgcctt ctcagattct tctggtgtca tcagcatcaa
    37561 aacttggtaa ataggttgat tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac
    37621 cttgctgacc atgcgattaa aagactgact caccgtccga gttaaaacag agggaacgaa
    37681 gcgactaatt cgttgggaaa aagaacccag accaaaggac atgattttag aacccaacat
    37741 ggcatccttg gtccctaagg caatctccgt gccctctttt ttagcatagc taattagatg
    37801 gcgcaaatgt aacttggaaa tagggctcgt gaacaagact ctgtctttac taaagatata
    37861 ctggccatta taggttaccg caaaatccag atccaaatcg tccatcaatt ccttaacaaa
    37921 aaaaggtcct cgccctgtcg ctacgccaac tagtacccct tgttctttga caatcttaat
    37981 cgcgtcctta gtggatttca aaacactctt gcgattgttg accaaggttc catcgatatc
    38041 aaaaaaaaca gctttgactt ccatcctatc ccaatctccc cttttgtgat acaatgatta
    38101 taccacattt cagaaagagt gagtaaatca tgcctaagaa aatccttgtt ttacatacgg
    38161 gtggaactat ttccatgcag gccgatgctt ctggcgctgt tgtgacgagt tcagataatc
    38221 ccatgaacca tgtgtccaac ccacttgaag gaatccaagt ccacgccttg gactttttta
    38281 accttccaag tccccatatc aaacccaaac atatgctggt cctctaccag aaaattaaag
    38341 aggaagcaga taactacgat ggagtggtga tcacacacgg aaccgatact ttagaggaaa
    38401 cagcctattt ccttgatacc atggaagttc cccatatgcc tatcgttcta acaggagcca
    38461 tgcgtagctc caatgagctc ggtagtgatg gtgtttataa ttacctaagt gctttacgag
    38521 tggccagcga tgacagggct gctgacaaag gagttttggt cgttatgaac gatgaaatcc
    38581 acgctgccaa gtatgtcacc aaaacacata cgactaatgt cagcaccttc cagactccaa
    38641 cacatggccc cctcggtctc atcatgaaac aggaaatcct ctacttcaaa acagctgaac
    38701 ctcgtgttcg ctttgacctt gatcacatac aaggtttagt ccctatcatc tcggcttatg
    38761 ctggtatgac agatgagctg attgatatgc tggatttaga acacttggac ggtttgatta
    38821 tccaagcctt cggagctggt aatattccca aagaaacggc tcaaaaatta gaaagccttc
    38881 tgcaaaaagg aattccagtc gctctggtat cacgatgctt taacggtatt gccgagcctg
    38941 tttatgccta ccagggtggg ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag
    39001 aactcaacgc ccaaaaagct cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag
    39061 gacaggcttt gaaaaactat atggaaggct aatactcttc gaaaatctct gcaaaccacg
    39121 tcacgtcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    39181 aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt gtgttgcgca
    39241 gcctttaacc agtcgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta
    39301 agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt
    39361 tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt
    39421 atgcataatc ttggtcaaca tacgcatact aatggcacca agatcataaa gaggttgggc
    39481 aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat
    39541 ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc
    39601 caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa
    39661 ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat
    39721 tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc
    39781 cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt aactcactgc
    39841 atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct caacatcgac
    39901 agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt
    39961 caagtgataa cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac
    40021 agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat
    40081 ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg
    40141 aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg
    40201 acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt
    40261 tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac
    40321 atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca
    40381 cattctttta caagtagagg tactgattga agctctatat ctacttacaa aagtgaagat
    40441 gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg taaacacttt
    40501 caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg
    40561 ctaccacctt agactaaaca caaaggagga aactaagccc tcctaaagtt atagtaaaat
    40621 gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    40681 agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc
    40741 aattttagca catagccttc ataaaaatat tatatcatca taaccaacca gattcttttg
    40801 cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata ttggtgacat
    40861 agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg ttggataagc
    40921 cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg ggacgggtca
    40981 tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg
    41041 tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatccact ccagccttga
    41101 ccgcacgttc aaaataccca gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa
    41161 gcctttctga tcgtatccac tccaagactt caagacctgt cttaacaggc atttctacgt
    41221 caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct tgcccattct
    41281 tggcttgaag gacagactcc acatctggtt gaagcgtgag caattgacac atggcatctc
    41341 gcaacatact ttgatcttct gcgactaata ctttcatctt agtttctctc cttataaggt
    41401 agtcgaactt gcacttccgt tggatgtttc tgactgatta cacttacttc tcctgaaaat
    41461 ggaaaaacac gatctcggac tgtatggagc tcatctcctt ttagaaaagc aaagccgcag
    41521 ccatcatcac ttactgttaa aatgagttcc ttctctgtcc gttctaattt taagtaagct
    41581 ttagacgctt tggcatgttt gatgatattg gtcaccaact caagcaaaat catagaagtc
    41641 attgcctcca attcttgagt aaggctagca gtatctagtt ggttatccgt ttccacctca
    41701 attccagcaa tttctaacat ctttttcaca gtctctagtt cggatgtcaa agttctagac
    41761 ttaagatttt ccacaatggt tcgaacttca cgcatcgatt ctttgctaat ttgctgtatt
    41821 tctcttaatt ccttttccac ttgtggataa gcctgcattt gaaatagctg caaggctaga
    41881 tctgtcttga cactaagcat agcaaaggta tgtcccagac tatcatgcaa atcctgaccg
    41941 atacgattgc gctcattttc tgctagcaat agatttatct gggtattttg ctcgacctga
    42001 gcttctttca aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat caaatcgaca
    42061 aaagtaagaa ttacaagcat atagactaga aactcaactt cgattctctg aaaaatcaaa
    42121 agtcgcccca caacaaggac ttgagcaagg agaaatgtcc atacatgtaa agactttaaa
    42181 ctacgtacgc caaaatgata aattaagaga ttggaaagga aaaagaaaaa ccagatataa
    42241 ttcccagcaa caaaggcggt attcccagct acatagacca gcatgatccc ccagaaaagc
    42301 caagataggc gctggttctt agttattaaa acacccaaat acgtcactac aaatagaata
    42361 tcaaccaata aatgccaagc aggaagctcc ccaatcacta caggtaggat gggaaaaagc
    42421 ataaaaatca aactgaccca aaacatatag tgtatgcttt tcagtctttc aagcattaag
    42481 cattctcctt atgaccttga aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa
    42541 gtaaataaac tgtggctgat agattgatgc caccctcgtt taagaaggtc ttgagcaact
    42601 ccatcaattg ataggtcggg agacacttac caactgcttg catccagtct ggaaataaag
    42661 aaatgggcat ccagagtccg cctaaaacag ccaatcctag ataaagaaga ttgcccacaa
    42721 cagacatcag ctgactagtt ggtaagagag tcaaggtcaa gccaagtgct acaaaagcaa
    42781 tactccccac aatcagcaaa atcgcagctc caacccattt tactagaggc atgtctacac
    42841 ctcttacaaa atgtccaact gtaaaaacaa ccagaattga gaccaaataa tcaaccagca
    42901 tacttgttat ctttgataga taatattcta ccatatttac agggctatga cgcaatgttt
    42961 tctgccagtt gttcatctta tcggtatgta aaacagctgg aaatgagagg atagttgtcg
    43021 acatcatgga aaaggcagtc atggagatga ggtaatcacg cataaaattc gcgggttcac
    43081 ctggtgtgtc ctgatagata ccagaaaaaa ataaatagaa agccgtcggc atccctaccg
    43141 acaatagata atagattaat tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta
    43201 tccatcgttt catcttagtt atctcccttc tgcgtctctt caaagattgt attcaacaaa
    43261 ctacgattat taacttcgat ttcttgcatc ctacatcctg cttgggctaa tagttcccag
    43321 aaagcatctg cttctcgagt gactacttgt aaagaatctt gctttagggt ccagttttca
    43381 accaaatttg actgctctac gacttccttg taagctatag gaaggataaa gtgcttttct
    43441 atttcctcgc tacgcatagc tagaggcgtc gtatctcgaa tcaactctcc cttatttaag
    43501 agcaaaatgc ggtctgcagt gtgttccact tcctcaatat aatgggacga atagagaatg
    43561 gtgactcctt gcgcttttaa ctcctggaca atttcccaaa aacgttgacg agttgaggta
    43621 tccatggacg cagtaggctc atctaaaaaa acaatctttg gtcgcccaat taaggtcaag
    43681 atgaaagaaa agagacgctt ttgaccgcct gataattttt ctgccaactg ttctttttgt
    43741 tgcttgacaa actgcaatag ttgatcaatt tcctgattgc tcaaaggatt tggatagata
    43801 cgttgaaaga aagcaatcaa ctctttaact tttaatttct gaacgattac attttcttga
    43861 gggaggtaag ccctagtata gtctaactta gaactcgtca ctggtaaacc ttgaatagat
    43921 acttgaccgc ttgtgaccag tttatctcca agcaaacaat ctaagagtgt tgtctttccg
    43981 gcaccatttg gaccaattaa ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc
    44041 cgcaaaattt ccttgtcttt tattttctta ctcaatttct caactttaac caccgtcatg
    44101 agactctcct ttcaaccact ccattcccat agggaaaacg acgaaaatca taaatccaaa
    44161 ccccaaagca ccatgaatga attggcgaag caaggcttga tcaaaccaat cagtaaacat
    44221 ttccactaac cataccaaga gtgacaggcc gataaagaaa tagatgatcc ctctcttcat
    44281 tcctcaaact cctttttcac atctctgact aatttcaaac cttctctaac aagccaagac
    44341 atgattccaa agccagcaaa gaccttccaa ggaaaatggt agaaatcctc atccaatccc
    44401 gaaaacatga gataggtcat aactcctgct actactaaac tcattgcaat aatcatttta
    44461 tttctcatct cttcttcccc catttcatac tacaattata gtcttttaaa atcagaggag
    44521 gcagaagctt ctgtcactag aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa
    44581 gcaagataca ctatacaata aaacacaatc agaaaaatct aaggcaactt cctcaaaaga
    44641 gatatcaaac tcaattcaca ccataatgta aactaatact tatttaaaat caaaaagagt
    44701 agaaattttt atcagacaaa cacat
//
LOCUS       DAVKUR010000012        40476 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKUR010000012 DAVKUR010000000
VERSION     DAVKUR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.012"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            54..169
                     /gene="rrf"
                     /locus_tag="VW749_000747"
     rRNA            54..169
                     /gene="rrf"
                     /locus_tag="VW749_000747"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            174..246
                     /locus_tag="VW749_000748"
     tRNA            174..246
                     /locus_tag="VW749_000748"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Val,seq:tac)
     gene            252..322
                     /locus_tag="VW749_000749"
     tRNA            252..322
                     /locus_tag="VW749_000749"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:284..286,aa:Gly,seq:tcc)
     gene            357..430
                     /locus_tag="VW749_000750"
     tRNA            357..430
                     /locus_tag="VW749_000750"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:391..393,aa:Ile,seq:gat)
     gene            513..602
                     /locus_tag="VW749_000751"
     tRNA            513..602
                     /locus_tag="VW749_000751"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:549..551,aa:Ser,seq:tga)
     gene            613..686
                     /locus_tag="VW749_000752"
     tRNA            613..686
                     /locus_tag="VW749_000752"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:647..649,aa:Met,seq:cat)
     gene            690..762
                     /locus_tag="VW749_000753"
     tRNA            690..762
                     /locus_tag="VW749_000753"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:723..725,aa:Phe,seq:gaa)
     gene            775..855
                     /locus_tag="VW749_000754"
     tRNA            775..855
                     /locus_tag="VW749_000754"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:809..811,aa:Tyr,seq:gta)
     gene            860..930
                     /locus_tag="VW749_000755"
     tRNA            860..930
                     /locus_tag="VW749_000755"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:892..894,aa:Trp,seq:cca)
     gene            945..1017
                     /locus_tag="VW749_000756"
     tRNA            945..1017
                     /locus_tag="VW749_000756"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:978..980,aa:His,seq:gtg)
     gene            1028..1099
                     /locus_tag="VW749_000757"
     tRNA            1028..1099
                     /locus_tag="VW749_000757"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1060..1062,aa:Gln,seq:ttg)
     gene            1109..1192
                     /locus_tag="VW749_000758"
     tRNA            1109..1192
                     /locus_tag="VW749_000758"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1143..1145,aa:Leu,seq:caa)
     gene            1299..2576
                     /locus_tag="VW749_000759"
     CDS             1299..2576
                     /locus_tag="VW749_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0174826.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2652..4136
                     /locus_tag="VW749_000760"
     CDS             2652..4136
                     /locus_tag="VW749_000760"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0174827.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            4197..5477
                     /locus_tag="VW749_000761"
     CDS             4197..5477
                     /locus_tag="VW749_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0174828.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5481..6101
                     /locus_tag="VW749_000762"
     CDS             5481..6101
                     /locus_tag="VW749_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0174829.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6267..7409
                     /locus_tag="VW749_000763"
     CDS             6267..7409
                     /locus_tag="VW749_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0174830.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7815..8153
                     /locus_tag="VW749_000764"
     CDS             7815..8153
                     /locus_tag="VW749_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0174831.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8164..8522
                     /locus_tag="VW749_000765"
                     /pseudo
     CDS             8164..8522
                     /locus_tag="VW749_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8629..9246
                     /gene="pcp"
                     /locus_tag="VW749_000766"
                     /pseudo
     CDS             8629..9246
                     /gene="pcp"
                     /locus_tag="VW749_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9274..10131)
                     /locus_tag="VW749_000767"
     CDS             complement(9274..10131)
                     /locus_tag="VW749_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0174832.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVFFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10261..11403
                     /gene="tgt"
                     /locus_tag="VW749_000768"
     CDS             10261..11403
                     /gene="tgt"
                     /locus_tag="VW749_000768"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0174833.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11501..13318
                     /locus_tag="VW749_000769"
     CDS             11501..13318
                     /locus_tag="VW749_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0174834.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTV
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13471..14622
                     /gene="nagA"
                     /locus_tag="VW749_000770"
     CDS             13471..14622
                     /gene="nagA"
                     /locus_tag="VW749_000770"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0174835.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14785..15843
                     /locus_tag="VW749_000771"
     CDS             14785..15843
                     /locus_tag="VW749_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0174836.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15994..16359
                     /locus_tag="VW749_000772"
     CDS             15994..16359
                     /locus_tag="VW749_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0174837.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16435..17376
                     /locus_tag="VW749_000773"
     CDS             16435..17376
                     /locus_tag="VW749_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0174838.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17324..18340
                     /locus_tag="VW749_000774"
     CDS             17324..18340
                     /locus_tag="VW749_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0174839.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18342..18668
                     /gene="comGC"
                     /locus_tag="VW749_000775"
     CDS             18342..18668
                     /gene="comGC"
                     /locus_tag="VW749_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV0174840.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18637..19065
                     /locus_tag="VW749_000776"
     CDS             18637..19065
                     /locus_tag="VW749_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0174841.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSIIF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19070..19330
                     /locus_tag="VW749_000777"
     CDS             19070..19330
                     /locus_tag="VW749_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174842.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQININGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19293..19754
                     /locus_tag="VW749_000778"
     CDS             19293..19754
                     /locus_tag="VW749_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0174843.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS"
     gene            19732..20145
                     /locus_tag="VW749_000779"
     CDS             19732..20145
                     /locus_tag="VW749_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0174844.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20282..20869
                     /locus_tag="VW749_000780"
     CDS             20282..20869
                     /locus_tag="VW749_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0174845.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQAHLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20930..21883
                     /locus_tag="VW749_000781"
     CDS             20930..21883
                     /locus_tag="VW749_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0174846.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVELFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21934..23124
                     /locus_tag="VW749_000782"
     CDS             21934..23124
                     /locus_tag="VW749_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0174847.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23273..23644
                     /gene="rnpA"
                     /locus_tag="VW749_000783"
     CDS             23273..23644
                     /gene="rnpA"
                     /locus_tag="VW749_000783"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0174848.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23619..24443
                     /locus_tag="VW749_000784"
     CDS             23619..24443
                     /locus_tag="VW749_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0174849.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24462..25448
                     /locus_tag="VW749_000785"
     CDS             24462..25448
                     /locus_tag="VW749_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0174850.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25499..26122
                     /locus_tag="VW749_000786"
     CDS             25499..26122
                     /locus_tag="VW749_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0174851.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26253..27710
                     /locus_tag="VW749_000787"
     CDS             26253..27710
                     /locus_tag="VW749_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0174852.1"
                     /translation="MEVISSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27733..28014
                     /locus_tag="VW749_000788"
     CDS             27733..28014
                     /locus_tag="VW749_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0174853.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28091..28576
                     /locus_tag="VW749_000789"
     CDS             28091..28576
                     /locus_tag="VW749_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0174854.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28593..29258
                     /locus_tag="VW749_000790"
     CDS             28593..29258
                     /locus_tag="VW749_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0174855.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29262..30125
                     /locus_tag="VW749_000791"
     CDS             29262..30125
                     /locus_tag="VW749_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0174856.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            30127..30831
                     /locus_tag="VW749_000792"
     CDS             30127..30831
                     /locus_tag="VW749_000792"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0174857.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIIVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            31010..32683
                     /locus_tag="VW749_000793"
     CDS             31010..32683
                     /locus_tag="VW749_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0174858.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32795..33886
                     /gene="ulaG"
                     /locus_tag="VW749_000794"
     CDS             32795..33886
                     /gene="ulaG"
                     /locus_tag="VW749_000794"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0174859.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            34000..35976
                     /gene="tkt"
                     /locus_tag="VW749_000795"
     CDS             34000..35976
                     /gene="tkt"
                     /locus_tag="VW749_000795"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0174860.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            36093..36392
                     /gene="yajC"
                     /locus_tag="VW749_000796"
     CDS             36093..36392
                     /gene="yajC"
                     /locus_tag="VW749_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0174861.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36439..36867
                     /locus_tag="VW749_000797"
     CDS             36439..36867
                     /locus_tag="VW749_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0174862.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEILYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36869..37279
                     /locus_tag="VW749_000798"
     CDS             36869..37279
                     /locus_tag="VW749_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174863.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37580..40231
                     /gene="adhE"
                     /locus_tag="VW749_000799"
                     /gene_synonym="adhC"
     CDS             37580..40231
                     /gene="adhE"
                     /locus_tag="VW749_000799"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0174864.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12266 a         7249 c         9142 g        11819 t
ORIGIN      
        1 acggttttct tgaattgaat agatattcaa ttttgagtag gtattactca gagttaagtg
       61 acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag ccctagaacg
      121 ccggaagtag ttgggggttg ccccctgtga gatagggaag tcgcttagct ctagggagtt
      181 tagctcagct gggagagcat ctgccttaca agcagagggt cagcggttcg attccgttaa
      241 ctcccatttt agcgggtgta gtttagtggt aaaactacag ccttccaagc tgttgtcgcg
      301 agttcgattc tcgtcacccg ctttgaactt tgttctttgt accaagtttt tgacttgggc
      361 gcgtagctca ggtggttaga gcgcacgcct gataagcgtg aggtcggtgg ttcgagtcca
      421 ctcgtgccca tagtgtttag tccattacta ggggattgga atattatctg ttcactaaga
      481 ggacacgggc ttgttcccgt ataaactatt ttggaggatt acccaagtcc ggctgaaggg
      541 aacggtcttg aaaaccgtca ggcgtgtaaa agcgtgcgtg ggttcgaatc ccacatcctc
      601 cttttatatt aacgcgggat ggagcagctc ggtagctcgt cgggctcata acccgaaggt
      661 cgtaggttca aatcctgctc ccgcaataag gctcggtagc tcagttggta gagcaatgga
      721 ttgaagctcc atgtgtcggc ggttcgattc cgtctcgcgc catttatata ttttggaagg
      781 gtagcgaaga ggctaaacgc ggcggactgt aaatccgctc cttcgggttc gggggttcga
      841 atccctcccc ttccatttta cgggcatagt ttaaaggtag aactaaggtc tccaaaacct
      901 tcagtgtggg ttcaattcct actgcccgtg ttaatagaat tatggcgggt gtggtgaagt
      961 ggttaacaca ccagattgtg gctctggcat gcgtgggttc gatccccatc actcgcctat
     1021 tttatattgg ggtatagcca agcggtaagg caagggactt tgactccctc atgcgttggt
     1081 tcgaatccag ctaccccagt tactatttgc cggcgtggcg gaattggcag acgcgctgga
     1141 ctcaaaatcc agtgtccgca aggacgtgcc ggttcgaccc cggccgccgg tatagtatag
     1201 tgttaggaac gttgttattc ttcgttcctt ttttatatta tttttggtat aattatagtt
     1261 attcaaattt tgtttagatt gagaaagtgt agggtagtat gtcttgttct atcgatttat
     1321 taaaacatcg gtatttgaaa aatattaaag aaaatcctga attgtttgtc ggaattgagt
     1381 tggagtatcc tgttgcaagt ttagaagggg atgctacaga tgttgaagtt ataaaggatc
     1441 tatttcatta tttagtttct actttggatc tcaccgtagc aaaggtagat gattttggca
     1501 atctgatcca gttagtagat ccgataagtc aggatgctat tttatttgaa gtttcctata
     1561 caacgattga gtttgcattt ggtaaggctg aaacgattca agaggtcgaa aatcgtttca
     1621 ataattatat gaatgtaatt cagagaaagt tagctgaatc aaatcatgct attgttggct
     1681 gtggtatcca tcccaactgg gataaaaatg agaattgtcc agtggcttat ccacgctatc
     1741 agatgttgat ggattatttg aatttgagta gaaatattat taaatcagat ttacatcatt
     1801 tccctgaata tggtactttt atctgtggga gccaggttca gctggatatt tcaaaaacca
     1861 actacttacg ggtgattaat gcttttactc aaattgaagc ggctaaggct tatttatttg
     1921 caaactctga attttcgggt gcggattggg atacgaaaat ttcaagggat attttctggg
     1981 aagaatctat gcatggtatc tatccagaga atgttggggt caatgctaga ctccttaatg
     2041 atgaagctga tttttttgac tatctaaatc attctgcgat ttttactgcg gaacgtgatg
     2101 ggcagaccta ttatttttat cctattcagg ctggggacta tttggctacg cctgaaatcc
     2161 aagcatttgc tctgaatggg gatgaggtta ttatttcccc ccaagagaag gattttgaaa
     2221 ctcatcgtag ttaccagtac caagacttaa cgactcgagg aacagttgag tttcgtagtg
     2281 tgtgtacaca gccacttgat aggacttttg cttctgcagc ttttcacttg ggattattgg
     2341 ttaatttaga caagttagaa gcttacttag aaacagcacc tttctttaaa gtatttggtt
     2401 atgattacaa gtctttaagg agacaatttt ctaagaaaaa tcttacagat gaggaagaaa
     2461 ctacgattat tgaattttcc aaagacttac tcctactagc tgaggaggga ctagtggtga
     2521 gaaataagga agaaatgacc tatttacagc ctttgagaga agaattgagc ctataatttc
     2581 tcttataaag ggagaatttt ctgaaaaatc atgatataat ggacgagact atagataaag
     2641 gatagagagt aatgacatta gtttatcaat caacgcgtga tgccaacaat acagtaactg
     2701 ccagccaagc aattttgcaa ggtttggcga cggacggcgg tttgtttaca ccggttactt
     2761 atccaaaggt agatttggac tttgacaaat tgaaagatgc ttcttaccag gaagttgcta
     2821 agctagtttt gtcagcattt ttagatgact ttacagctga ggagttggac tactgtatca
     2881 acaatgccta cgatagcaaa tttgatactc cagctattgc actattagtg aaattagatg
     2941 ggcaatacaa tttggaactt ttccatggtt caacgattgc ctttaaggat atggccttgt
     3001 ctattttgcc atactttatg acgactgctg ctaagaaaca tggtttggag aacaagattg
     3061 ttatattgac agcgacatct ggtgacacgg ggaaagctgc tatggcgggg tttgcggatg
     3121 tgcctggtac tgagattatc gtcttttatc caaaggatgg tgtcagcaag attcaagagt
     3181 tacaaatgac cactcagact ggcgacaata ctcatgttat tgctattgat ggtaactttg
     3241 acgatgcgca aacaaatgtg aagcacatgt ttaacgatgt ggctcttcgt gaaaaattga
     3301 ctaccaacaa gttgcaattt tcatcagcta actctatgaa cattggtcgt ctggtgccac
     3361 aaattgttta ttatgtttat gcttacgctc aattggttaa gactggtgaa attgtagctg
     3421 gtgaaaaggt taacttcaca gtaccaacag gaaactttgg aaatatcttg gctgcctttt
     3481 atgccaaaca aattggtttg ccagttggta aattgatctg tgcttcaaat gacaacaatg
     3541 ttttgacaga cttctttaaa acacgtgtct atgacaaaaa acgtgagttt aaggtaacaa
     3601 ccagcccatc tatggatatc ttggtatctt caaacttgga gcgcttgatt ttccatcttt
     3661 tgggaaataa tgctgaaaag acagctgaac tcatgaatgc tttgaacatg caaggacaat
     3721 ataagttgac agactttgat gcagagattc tggagctctt tgcagctgaa tatgcgactg
     3781 aggaagaaac agcggcagaa atcaagcgtg tttatgagtt agattcttat attgaggatc
     3841 cacatacggc ggttgcctca gcagtttata gaaaatacca agcggttact gatgatgcga
     3901 ctaagacagt gattgcttca acagctagtc cctacaagtt cccagtagtt gcagtagaag
     3961 ctgtaactgg aaaagcaggt ttaacagact ttgaagcctt ggctcaatta catgaaatct
     4021 caggcgttgc agtgccacca gcagttgatg ggcttgagac agctcctgtt cgtcacaaga
     4081 caactgtagc ggctgctgat atgcaagcag cggttgaggc ttatttagga ctttaagata
     4141 gagggagtaa actcggttgg gaaaccaact gagtttcttt tcatcaggag gagagattgt
     4201 ttaagaaaaa taaagacatt cttaatattg cattgccagc tatgggtgaa aactttttgc
     4261 agatgctaat gggaatggtg gacagttatt tggttgctca tttaggattg atagctattt
     4321 caggggtttc agtagctggt aatattatca ccatttatca ggcgattttc atcgctctgg
     4381 gagctgctat ttccagtgtt atttcaaaaa gcatagggca gaaagaccag tcgaagttgg
     4441 cctatcatgt gactgaggcg ttgaagatta ccttactatt aagtttcctt ttaggatttt
     4501 tgtccatctt cgctgggaaa gagatgatag gacttttggg gacggagagg gatgtagctg
     4561 agagtggtgg actgtatcta tctttggtag gcggatcgat tgttctctta ggtttaatga
     4621 ctagtctggg agccttgatt cgtgcaacgc ataatccacg tctgcctctc tatgttagtt
     4681 ttttatccaa tgccttgaat attctttttt caagtctagc tatttttgtt ctggatatgg
     4741 ggatagctgg tgttgcttgg gggacaattc tgtctcgttt ggttggtctt gtgattttgt
     4801 ggtcacaatt aaaactgcct tatgggaagc caacttttgg tttagataag gaactgttga
     4861 ccttggcttt accagcagct ggagagcgac ttatgatgag ggctggagat gtagtgatca
     4921 ttgccttggt cgtttctttt gggacggagg cagttgctgg gaatgcaatc ggagaagtct
     4981 tgacccagtt taactatatg cctgcctttg gcgtcgctac ggcaacggtc atgctgttgg
     5041 cccgagcagt tggagaggat gattggaaaa gagttgctag tttgagtaaa caaacctttt
     5101 ggctttctct gttcctcatg ttgcccctgt cctttagtat atatgtcttg ggtgtaccat
     5161 taactcatct ctatacgact gattctctag cggtggaggc tagtgttcta gtgacactgt
     5221 tttcactact tgggacccct atgacgacag gaacagtcat ctatacggca gtctggcagg
     5281 gattaggaaa tgcacgcctc cctttttatg cgacaagtat aggcatgtgg tgtatccgca
     5341 ttgggacagg atatctgatg gggattgtgc ttggttgggg cttgcctggt atttgggcag
     5401 ggtctctctt ggataatggt tttcgctggt tatttctacg ctatcgttac cagcgctata
     5461 tgagcttgaa aggataggaa atgcaaaaaa cagcttttat ttgggattta gacgggactt
     5521 tattggactc ttacgaagcg attttatcag ggattgagga gacttttgct cagttttcta
     5581 ttccttatga taaggagaag gtgagagagt ttatcttcaa gtattcggtg caaaatttgc
     5641 ttgtgcgggt ggcagaagat agaaatctgg atgttgaggt gctaaatcag gtgcgtgccc
     5701 agagtctggc tgagaaaaat gctcaggtag ttttgatgcc aggtgcgcgt gaggtgctag
     5761 cttgggcaga cgaatcagga attcagcagt ttatatatac tcataagggg aacaacgctt
     5821 ttaccattct caaggacttg ggggtggaat cctattttac agagatttta accagtcaga
     5881 gtggctttgt gcggaagcca agtccagaag cggctaccta tctgctagat aagtatcagt
     5941 tgaattctga taatacttat tatatagggg atcggactct ggatgtggaa tttgcccaga
     6001 atagtgggat tcaaagtatc aactttttag agtctactta tgaagggaat cacaggattc
     6061 aagcgttagc agatatttcc cgtatttttg agactaagtg ataaaaagat tgtgtcagtt
     6121 ttgtgacaga gacctaacaa actatttcaa gtaacctagt ttgttacaag gaatagacag
     6181 ttctgttaaa taggcccgag agggcttttt ttctacattt tttgtgttat gatagacagg
     6241 tactaatttg aaaggaattt gaaagaatga agaaaagaat gttattagcg tcaacagtag
     6301 ccttgtcatt tgccccagta ttggcaactc aagcagaaga agttctttgg actgcacgta
     6361 gtgttgagca aatccaaaac gatttgacta aaacggacaa caaaacaagt tataccgtac
     6421 agtatggtga taccttgagc actattgcag aagccttggg tgtagatgtc acagtgcttg
     6481 cgaatctgaa caaaatcact aatatggact tgattttccc agaaactgtt ttgacaacga
     6541 ctgtcaatga agcagaagaa gtaacagaag ttgaaatcca aacacctcaa gcagactcta
     6601 gtgaagaagt gacaactgcg acagcagatt tgaccactaa tcaagtgacc gttgatgatc
     6661 aaactgttca ggttgcagac ctttctcaac caattgcaga agctccaaaa gaagtagcat
     6721 caagttcaga agttacaaag acagtgattg cttctgaaga agtggcacca tctacgggca
     6781 cttctgtccc agaggagcaa acggccgaaa caagcagtgc agttgcagaa gaagctcctc
     6841 aggaaacgac tccaggtgag aagcaggaaa cacaagcaag ccctcaagca gcatcagcag
     6901 tggaagcaac tacaacaagt tcagaagcaa aagaagtagc atcatcaaat ggagctacag
     6961 cagcagtttc tacttatcaa ccagaagaga cgaaaataat ttcaacaact tacgaggctc
     7021 cagctgcgcc cgattatgct ggacttgcag tagcaaaatc tgaaaatgca ggtcttcaac
     7081 cacaaacagc tgcctttaaa gaagaaattg ctaacttgtt tggcattaca tcctttagtg
     7141 gttatcgtcc aggagacagt ggagatcacg gaaaaggttt ggctatcgat tttatggtac
     7201 cagaaagttc agaattaggg gataagattg cggaatatgc tattcaaaac atggccagcc
     7261 gtggcattag ttacatcatc tggaaacaac gtttctatgc tccattcgat agcaaatatg
     7321 ggccagctaa cacttggaat ccaatgccag accgtggtag tgtgacagaa aatcactatg
     7381 accacgttca cgtttcaatg aatggataaa cccgacttgg taacatcatt ttgacgaatg
     7441 agatctagct ttcgtgatag gaagcgattc tcgttcgttt tttctttgtc atactcttcg
     7501 aaaatctctt caaaccacgt cagttttatc tgaaacctca aagctgtgct ttgagcaacc
     7561 tgcgactagc tttctagttt actctttgat tttcattgag tatcaatttg aatggaaaat
     7621 ggaaagttat tatcttgtaa taatccaagc aacattcttg caatctattt tactttatat
     7681 cacaattgat tggtcaacta ttgataagtc aatggatagg aggaagaaat gatagagatt
     7741 caagatttac tgtatcaact ccgcttgtct gagcaagcga gtacgcaatt gtttgaaaaa
     7801 ggcttgggat tagtttgaca cggtatcaga ttttactgtt tttgctggag cattctcctt
     7861 gtaaccaaat ggcggttcag gagcgtttga aaattgatca ggctgctttg acacggcatt
     7921 tcaagatttt ggaaacggaa ggtttggtgg agcgtcatcg taatcctgaa aatcagcggg
     7981 aagtgttggt agaggctgcg aagtatgcca aggagcagtt agtggtgaat ccccctctgc
     8041 aacatatcaa ggttaaggaa gagatggaaa gtatcttaac agagtttgag agaacagaac
     8101 tcagccgttt attaaataaa ttggttttgg gtattgaaaa tatagaaatt taaggagaaa
     8161 tagatgtcaa ttattttaac aacgatcgtt gctttggagc atttttacat tttttatttg
     8221 gaaagtattg ccacgcaatc agatgcgact agtcgtgtat ttaatatgga aaaggaagaa
     8281 ttggctcatc cgtcagtaag ttcattgttc aaaaatcaag gaatttataa ggctctgcta
     8341 ggagtctttc tcttgtatgt catttatttc tcacagaatt tagaaattgt gactattttt
     8401 gtcttatttg tgattggtgc tgcgacttac ggctctttaa cagcggataa aaaattattt
     8461 tgaagcaagg tggatcagct attttggcct tgattagtat tttactcttt aaatacactt
     8521 gaaggttgat tctaatctcg ctaatccttt ttaatccaga ataagggaaa tatgttatac
     8581 ttgtttttaa gaaaaaagtc tcattgaatt ggttttgagg agttagaaat gaaagtatta
     8641 gtgacaggtt ttgagccctt ttgaggccat taaaggttta ccagctgaaa tccatggtgc
     8701 tgaggtccgt tagctagagg tgccgacagt ttttcacaaa tctgctcaag tattggaaga
     8761 agagatgaat cgttatcaac ctgactttgt cctttgtatt gggcaagctg gtggaagaac
     8821 tagtttgaca cctgaacgag tggccattaa tcaagacgat gcacgcattt ctgataacga
     8881 agataatcaa ccgattgacc gtcccattcg cccagatggt gcttcggcct actttagtag
     8941 tttgccgatt aaagcgatgg ttcaagctat aaaaaagagg gcttaccggc ctctgtttcc
     9001 aatacggcag ggacttttgt ctgcagccat ttgatgtatc aggctctcta tttggtagaa
     9061 aagaaatttc catatgttaa ggcaggtttt atgcatattc cttatatgat ggaacaggtg
     9121 gtgaacagac agactattcc agctatgagt ttagtggata ttcggagagg gatagaagca
     9181 gcaatcggcg ctatgataga acatggagat caggaactca agttggtagg cggagaaact
     9241 cattgataga aaaaagcttg agtggaaaaa ccttcaagct tttggacgtt ttcgagccaa
     9301 tactgctcgg taaaacataa ttttagtgca ttggatataa ggtaggagtg aaaaactagc
     9361 aatgccaaag gtaatccaat tgaggaagta ccaaggaaga agctgtaaat ctaggacaaa
     9421 gcgctggaac ttgtagccct tcataaagga acggctagtt tttaggattc gtcttggtgg
     9481 gacctgtcct aggtctagac tataacagag aagaaattcc acctgtgaat aggcataata
     9541 ctgtggaata tagaggatat ttcctacaat gatcaagatg agacttgcaa gaaagtagag
     9601 tccaaagacc atgaggaaac gctcggtttc aactgatgag agatctagat ttggaaactc
     9661 aggatgtagg gtgacgaatt ttttggctaa aaagctacta taaaagagga ggtaaatccc
     9721 aagtaaatta gggatactcc ataaaaagag atagaaacgt ttgagaagta gggtcaaaaa
     9781 ggtttgagaa aagcgctcct catcaaagag agctaggctg ttttttacag atggctccgt
     9841 tttagaatct ttcatgagtg tcagtgttgc atagacggaa ctggtcaaaa gaatagtccc
     9901 gataaagaag actagtagag gaaagaggta ggcttgaagt atttggccaa gtatgctgaa
     9961 aaatggctgt tctaaaacag tcccgtggat ccgagataag ggattaagaa aactagataa
    10021 gatgaccagc atactgggaa ggatatagag gagaaagaga cggggggtgt cagcctgaaa
    10081 atgttttgac tcctgacgaa ttgtttttaa atcaattttt ggatagttca ttctcttatt
    10141 ataccatagt tcttatacat agttcgtgac agttcctact ttttttgata aaatcataca
    10201 gtgtgtcctt gggcacactg tatgaactgg gactgtcttt cccagcttcg gaggtaaaaa
    10261 atgtcagatt caccaatcaa atatcgtttg attaagaaag aaaaacacac aggagctcgt
    10321 ctgggagaaa tcatcactcc ccacggtacc tttccgacac ctatgtttat gccagttggg
    10381 acacaagcca ctgtcaaaac tcagtcacct gaagaattga aggagatggg ttcgggaatt
    10441 atcctatcaa acacctatca tctctggctt cgccctggag atgaactcat tgcacgcgct
    10501 ggtggtctcc acaagttcat gaattgggac cagcctatct tgacagatag tggtggtttt
    10561 caggtttatt ctttagcaga tagccgtaat atcacagaag aaggagtaac ctttaaaaat
    10621 catctaaatg gttctaagat gttcctatcc ccagaaaaag ccatctctat tcagaataat
    10681 ctgggttcag acatcatgat gtcctttgat gaatgtcctc agttttatca accttatgac
    10741 tacgttaaga aatcgatcga gcgtaccagc cgttgggctg agcgtggttt gaaggctcac
    10801 cgtcgtccac atgaccaagg tttgtttgga attgtgcaag gtgcaggatt tgaagacctt
    10861 cgccgccaat cagctcatga tcttgtcagc atggatttct caggctactc tatcggtggt
    10921 ttggcagtgg gagaaaccca tgaagagatg aatgcggtct tggactttac aactcaactg
    10981 ctacctgaaa ataaacctcg ttatctgatg ggtgtgggag cgccagatag cttgatcgat
    11041 ggggtcattc gtggggtgga tatgtttgac tgtgtcttac cgactcgaat tgctcgtaac
    11101 gggacttgta tgaccagtca aggacgtttg gttgtgaaaa atgcccagtt tgctgaggac
    11161 tttacgccac tggatcctga gtgtgactgc tacacatgta ataactatac acgcgcttac
    11221 cttcgtcacc tgctcaaggc tgatgaaacc tttggtatcc gcttgactag ctaccacaat
    11281 ctttacttct tgcttaacct gatgaagcaa gtgcgacaag ccatcatgga tgacaatctc
    11341 ttggaattcc gtgagtattt tgtggaaaaa tatggctata ataagtcagg acgtaatttc
    11401 taaaatggaa ttgatataaa aaaatcctaa gttttctctt aggatttttc ttcttttttt
    11461 gatagaataa agtgtacaat gaaaggaaga ataaactcgt atgcgcatta aatggttttc
    11521 cttgattagg attataggtt tacttttggt actcttgtat cacttctttc agacgatctt
    11581 tcctggagga ttcttcgggg tagatgtctt tttcacattt tcaggtttcc tgattacagc
    11641 tctactcatt gaagaatttt ctaagaacaa tgagattgat ttgataggat tttttagaag
    11701 acgcttttat cggattgtgc cacctgtggt tttgatggtc ttggtgacca tgccttttac
    11761 tttcttggtt cgccaagact atgttgctgg aattggtggc cagattgcgg gcgtcttagg
    11821 ctttatgacc aacttctatg aactcctaac aggtgggagt tatgaatctc agttcattcc
    11881 tcatttgttt gttcataatt ggagtttggc agttgaggtt cactactata ttctttgggg
    11941 attggcagtt tggttcttat ccaaacaagc taaatcaaat ggtcagttga aggggatggt
    12001 ctttctctta tctgctgctg ccttcttgat cagtttcttc tccatgttta ttggtagttt
    12061 tctagtgacc tcttattcct ctgtttattt ctccagttta actcatgtct atccattctt
    12121 tttgggaagt atgttagcaa ctattgtagg cgttcgtcag acgacttccc tcgtcaagca
    12181 gttggataaa atctgggatt tacgaaagac tttggtagtt tttggaggag gctttggttt
    12241 cctagttctt ttgactttct ttgtcaaatt cacttatctt tttgcctatc ttatcggctt
    12301 cttgcttgcc agtcttgcag ctcttgccat gattctggcg gcgcgtgtct tacatgaaaa
    12361 gacacatcat atacaggagc cgaagattat cagcttttta gcggatacta gctatgcggt
    12421 ttatcttttc cattggcctt tctatatcat tttctcacag ttgacatcaa atcttcttgc
    12481 tgtattactg actctgattt gttcttatgg ctttgccagt ctgtcattct atgtattgga
    12541 accttggatt gcaggcaaga acacacctat tttacaaact cttcgtcccc tgccttatat
    12601 tcacgcaatt cttgcagcag gtacaggaat cttgaccttc attgtctgca tggtgacctt
    12661 gttggcacca caagtgggag cgtttgagac agacttgact gtcaatggct tgaagcaagc
    12721 tgcaacaaat attggccaga ccaaggtgat ggcagaacgg gcagatgcaa acagtttggg
    12781 aattgctgat ggcactatgt taattggtga ctcagtggct ttaagggcaa atacagcact
    12841 acagacagtt cttcctggag cacagattaa cgcgcaggtc agcgtaacaa ccaagaccgc
    12901 aaatgaaatc atgctaaata atagccagaa taaattttta cctaagacgg tggtcattgc
    12961 gactggggta aataatcctg agaattacaa ggatgactgg gacagtatcg tgaaaaatct
    13021 tcctaaggga caccatatga ttttggtgac tccttatgag ggagataaga caaaagagac
    13081 ctatgccatc gttgagaagg ctgctgccta tatgagagaa ttggcagaga agacacctta
    13141 cattacgata gcagattgga atcaagttgc gaaagagcat ccagaaattt gggcaggaac
    13201 agaccaggtt catttcggga gtgagagtag cactatcgaa gcaggagcaa aattgtatgc
    13261 agatacgatt gccacagctt tgcagacagc tcaagacaag ccggttaaat caaaataact
    13321 tgtattaaaa aagagaagag ttggagaaat ccagctcttt taaaatatct ccaaaaaata
    13381 ggtctatacc atttacaaat aaaaaagaaa ggtttataat gtaattgaca taataaattg
    13441 tagaatcaat cttttaagga ggttaacatt atgcctaact atattaaagc ggatcagttt
    13501 ttctacccac acggagttcg tcgaggtggt tacttggaac ttgtggacgg caagtttggg
    13561 aaacatgtag agcagattcc tgaaggggct gaggtgattg actatacagg ttatagcatt
    13621 gccccaggtc ttgtggatac tcatattcat ggatatgcag gtgtagatgt gatggacaac
    13681 aacattgaag gtacattgca tactatgagt gaaggacttc ttagtaccgg tgttaccagt
    13741 ttcttaccca caactttaac agccacttat gagcaattgc ttgcagtcac tgaaaatctt
    13801 ggaaaccatt ataaagaagc aacaggtgct aagattcgtg ggatttatta tgaaggtcca
    13861 tatttcacag aaacttttaa gggggcacaa aatccaactt atatgagaga cccgggtgtt
    13921 gaggagtttc attcttggca aaaagcggca aatggcttgc ttaataaaat tgcccttgca
    13981 ccagaacgtg atggggtgga agactttgtt cgtacagtta cgggcgaagg tgtgacggtt
    14041 gctcttggac attcaaacgc gacttttgat gaagccaaaa aagcagtcga tgctggagcg
    14101 agtgtttggg tgcatgccta caatggaatg cgtgggttga ctcaccgtga attgggtatg
    14161 gttggagcca tgtaccaatt gccacatacc tatgcagagt tgatctgtga tggtcaccac
    14221 gtagatccaa aggcttgcga aattcttatc aaacaaaaag gaacagaaaa catcgctctt
    14281 atcacagact gtatgacagc tgggggattg gaagacggag attatatgtt gggagaattc
    14341 ccagttgtcg ttgcaaatgg aactgcacgc ctcaaatcga caggtaactt ggcaggttct
    14401 atcctcaaac tcaaagatgg tttgaagaat gtggtcgaat ggggaattgc gaatccgcat
    14461 gaagcagtca tgatggccag cttcaaccca gctaaatccg ttcacatcga tgacgtctgt
    14521 ggccaaatcc gtgaaggcta cgacgctgac ttcatcgtat tagataaaga tttggaattg
    14581 gtagcaacct acctagatgg cgtgaaacgt tatcaagcat aagagagaaa gcagaagtta
    14641 gagactaact tctgcttttt tatgcagggt actttactgg taaataaaaa gttaaaaaaa
    14701 tcacaaaaaa agcttgaaga aacaaagaaa aaggcttaca attgaactat aaatattaca
    14761 aataaaaaaa cggaggagtg ctttatgaaa gcttatactt atgttaaacc aggacttgct
    14821 tcttttgttg atgtagacaa accagttatt cgcaagccaa cagacgctat tgtgcgtatt
    14881 gtaaaaacca ctatttgtgg aacagacctc catattatca aaggggatgt tcctacttgc
    14941 caaagtggta ccattcttgg ccacgaaggg attgggattg ttgaagaagt tggggaagga
    15001 gtttccaact tcaaaaaagg tgacaaggtc ttgatttctt gcgtctgtgc ctgtggtaaa
    15061 tgctactact gtaaaaaagg aatttatgcc cactgtgaag acgaaggggg ctggattttc
    15121 ggtcacttga ttgatggtat gcaggctgaa tatctacgtg tccctcatgc agataatact
    15181 ctttaccata ctccagaaga cttgtcagat gaagctttgg ttatgctgtc agacattctg
    15241 cctactggat atgaaattgg tgtcttaaaa gggaaagtag aacctggttg cagcgtagcc
    15301 attattggtt caggtccagt tggattggct gctcttttaa cagcccaatt ctattcacca
    15361 gctaaattga ttatggtaga cctagacgat aaccgtttgg aaactgccct atcattcggt
    15421 gcgactcata aggtaaactc ttcagaccct gaaaaagcga taaaagaaat ttatgatttg
    15481 acagatggtc gcggtgtaga tgtcgctatt gaagctgtag ggattcctga aacatttgat
    15541 ttctgtcaaa agattatcgg tgtagacgga acggttgcca actgtggtgt gcatggtaaa
    15601 ccagttgaat tcgatttaga taaactttgg attcgtaaca tcaatgtaac aactggtttg
    15661 gtatctacaa atacgactcc acaattgttg aaagcacttg aaagtcataa gattgaaccg
    15721 gaaaaattgg taactcacta tttcaaactc agtgaaattg aaaaagccta cgaagtcttc
    15781 agtaaggcag cagaccacca tgccattaag gtcattatcg aaaacgatat ctcagaagcc
    15841 taagtagtaa aaatattttt gtacataagc aaatagaaat tcagtcatcc atcagatggc
    15901 tggatttttt atcaaaaaat taagaaatga gcatatttct ttccttgtct ggcggaattg
    15961 gttataatat acggtacaaa ggaatgaatg aatatgtatc gtgttataga aatgtacgga
    16021 gattttgaac cgtggtggtt cttagaaggt tgggaagaag atattgtagc aagtagaaaa
    16081 tttgaccagt attatgatgc tctcaaatac tacaaaactt gctggtttag attagaacaa
    16141 gaatcccctc tttataaaag tagaagcgac ttgatgacca ttttttggga cccggaagac
    16201 caacgctggt gtgatgaatg tgatgagtat ttacaacaat accattcttt ggctcttttg
    16261 caggatgagc aggttatccc agacgaaaaa ctacgctcag gctatgaaaa acaaaccagt
    16321 caggaaagga atcgttcttg ccgtatgaaa ttaaaataga gaaaagtaac ttttttggag
    16381 ttgctttttt tatttttcta acgctttgcg aatagtatag gtgaggaggt aagtatggtt
    16441 caagaaattg cacaagaaat cattcgttcg gctcggaaaa aaggggcgca agacatttat
    16501 tttgtcccta agttagatgc ctatgagctt catatgaggg taggagacga gcgctgtaaa
    16561 attggtagct atgattttga aaagtttgca gccgttatca gtcactttaa gtttgtggcg
    16621 ggtatgaatg tgggagaaaa aagacgtagt caactgggtt cctgtgatta tgcctatgac
    16681 cagaagatgg cgtctctacg tttatctact gtaggcgatt atcgggggca tgagagtttg
    16741 gttatccgtt tgttgcacga tgaggagcag gacttgcatt tttggtttca ggatattgaa
    16801 gaattaggca agcagtacag gcaacgggga ctctatcttt ttgctggtcc ggttgggagt
    16861 ggtaagacga ccttgatgca tgaattgtcc aagtcactct ttaaaggaca gcaagttatg
    16921 tccatcgaag atcctgtcga aatcaagcag gacgacatgc ttcagttgca gttgaacgaa
    16981 gcaatcggcc taacctatga aaatctaatc aaactttcct tgcgtcatcg accagatctc
    17041 ttgattatcg gagaaattcg tgacagcgag acggcgcgtg cagtggtcag agctagtttg
    17101 acaggtgcga cagtcttttc aaccattcac gccaaaagta tccgaggtgt ttatgagcgt
    17161 ctgctggagt tgggtgtgag tgaagaagaa ttggcagttg ttctgcaagg agtctgctac
    17221 cagagattaa tcgggggagg aggaatcgtt gactttgcaa gcagagatta tcaagaacac
    17281 caagcagcca agtggaatga gcaaattgac cagcttctta aagatggaca tatcacaagt
    17341 cttcaggctg agacggaaaa aattagctac agctaagcaa aaaaatatca tcaccctatt
    17401 taacaatctc ttttctagcg gttttcatct ggtggagacc atctcctttt tagataggag
    17461 tgctttgttg gacaagcagt gtgtgaccca gatgcgtgtg ggcttgtctc aggggaaatc
    17521 attctcagaa atgatggaaa gtttgggatg ttcaagtacc attgtcactc agttatctct
    17581 agctgaagtt catggcaatc ttcacctgag tttgggaaag atagaagaat atctagacaa
    17641 tctggccaag gtcaagaaaa agttaattga agtagcgacc tatcctttga ttttgctggg
    17701 ttttcttctc ttaattatgc tggggctacg gaattacctg ctcccacaac tggatagtag
    17761 caatattgcc acccgaatta tcggtaatct gccacaaatt tttctaggca tggtagggct
    17821 tgtttccgtg cttgcccttt tagcactaac tttttataaa agaagttcta agatgagtgt
    17881 cttttctatc ttagcacgcc ttccctttat tggaatcttt gtgcagacct acttgacagc
    17941 ctattatgca cgtgaatggg ggaatatgat ttcacaggga atggagctga cgcagatttt
    18001 tcaaatgatg caggaacaag gttcccagct ctttaaagaa atcggtcaag atctggctca
    18061 aaccctgaaa aatggccgtg aattttctca gacgatagga acctatcctt tctttaggaa
    18121 ggaattgagt ctcatcatag agtatgggga agttaagtcc aagctgggta gtgagttgga
    18181 aatctatgct gaaaaaactt gggaagcctt ttttacccga gtcaaccgca ccatgaattt
    18241 ggtgcagcca ctggttttta tctttgtggc actgattatc gttttacttt atgcggcaat
    18301 gctcatgccc atgtatcaaa atatggaggt aaatttttaa aatgaaaaaa atgatgacat
    18361 tcttgaaaaa agctaaggtt aaagctttta cattggtgga gatgttggtg gtcttgctga
    18421 ttatcagcgt gcttttcttg ctctttgtac ctaatctgac caagcaaaaa gaagcagtca
    18481 atgacaaagg aaaagcagct gttgttaagg tggtggaaag ccaggcagaa ctttatagct
    18541 tggaaaagaa tgaagatgct agcctaagca agttaaaaga cgatgggcga atcacggaag
    18601 aacaggttaa agcttataaa gaatacaatg ataaaaatgg aggagcaaat cgtaaagtca
    18661 atgattaagg cctttaccat gctggaaagt ctcttggttt tgggtcttgt gagtatcctt
    18721 gccttgggct tgtccggctc tgttcagtcc acttttgcgg cagtagagga acagattttc
    18781 tttatggaat ttgaagaact ctatcgggaa acccaaaaac gcagtgtagc cagtcagcaa
    18841 aagactagtc tgaacttaga tgggcagatg attagcaatg gcagtcaaaa gttgccagtc
    18901 cctaaaggaa ttcaggcccc atcaggccaa agtattatat ttgaccgtgc tgggggcaat
    18961 tcgtccctgg ctaaggttga atttcagacc agtaaaggag cgattcgcta tcaattatat
    19021 ctaggaaatg gaaaaattaa acgcattaag gaaacaaaaa attagggcag tgattttact
    19081 ggaagcagta gtcgctctag ctatctttgc cagcattgcg accctccttt tgggacaaat
    19141 tcaaaaaaat aggcaagagg aagcaaaaat cttgcaaaag gaagaagtct tgagggtagc
    19201 taagatggcc ttgcagacgg ggcaaaatca gataaacatc aacggagttg agattcaggt
    19261 attttctagt gaaaaaggat tggaggtcta ccatggttca gaacagttgt tggcaatcaa
    19321 agagccataa ggtcaaggct tttaccttgt tagaatccct gcttgccctg cttgtcatca
    19381 gtgggggctt actccttttt caagctatga gtcagctcct catttcagaa gttcgctacc
    19441 agcaacaaag cgagcaaaag gagtggctct tgtttgtgga ccaacttgag gcagaattag
    19501 accgttcgca gttcgaaaaa gtagaaggca atcgcctata catgaagcaa gatggcaagg
    19561 acatcgccat cggtaagtca aagtcagacg attttcgtaa aaccgatgct agtggacgag
    19621 gttatcagcc tatggtttat gggctcaaat ccgcacagat tacagaggac aatcaactgg
    19681 tgcgctttcg tttccagttt caaaaaggct tagaaaggga gttcatctat cgtgtggaaa
    19741 aagaaaaaag ttaaggcagg tgttctcctc tacgcagtca ccatagcagc catctttagt
    19801 cttttgttgc aattttattt gaaccgacaa atcgcccact atcaagacta tgctttaaat
    19861 aaagaaaaat tggttgcttt tgccatggct aaacgaacca aggataaagc cgagcaagaa
    19921 agtggggaac aggtctttaa tctaggtcag gtaagctatc aaaacaagaa aacaagcttg
    19981 gtgacgactg ttcgtacgtc taagagccaa tatgagtttc tgtttccttc agtcaaaatc
    20041 aaagaagaga aaagagataa aaaggaagag gtagcgaccg attcaagcga aaaagtggag
    20101 aagaaaaaat cagaagagaa gcctgaaaag aaagagaatt cctagtcaat tcaactataa
    20161 tgcgttgaat ccagaatagt tcactgtagt ttctagaaaa ttgctggaaa tggatgttaa
    20221 gctccaattt atttgtttat atcttatttc agtttactat actttgtgct aaactaaaga
    20281 tatgaaacat gattttaacc acaaagcaga aactttcgat tcccctaaaa atatcttcct
    20341 cgcaaacttg gtatgtcaag cagtcgagaa acagattgat attttatcag acaaagaaat
    20401 tttagatttc ggtggtggca cgggtctatt agccttgccc ctagccaagc aggctaagtc
    20461 agttactctt gtagacattt ctgagaaaat gttggagcaa gctcatttga aagcggagca
    20521 gcaagcaatc aagaatatcc agtttttgga gcaagattta ccgaaaaatc ccttggagaa
    20581 agagtttgat tgccttgctg ttagtcgggt tcttcatcat atgcctgatt tggatgcggc
    20641 tctctcactg tttcatcaac atttgaagga agatgggaaa ctcatcattg ctgattttac
    20701 caagacagaa gctaatcatc atggatttga tttagctgaa ctggaaaaca agctaattga
    20761 gcatggtttt tcatctgtgc atagtcagat tctctatagc gctgaagact tgtttcaagg
    20821 aaatcactca gaattctttt taatagtagc ccaaaaatca ctcgcctagt cagggagtga
    20881 tttttctata aggatggaaa aaagaaggga aatttgataa gataggaata tggattttga
    20941 aaaaattgaa caagcttata cctatttact agagaatgtc caagtcatcc aaagtgattt
    21001 ggcgaccaac ttttatgacg ccttggtgga gcaaaacagc atctatctgg atggtgaaac
    21061 tgagctaaac caggtcaaag acaacaatca ggcccttaag cgtttagcac tacgcaaaga
    21121 agaatggctc aagacctacc agtttctctt gatgaaggct gggcaaacag aacccttgca
    21181 ggccaatcac cagtttacac cggatgctat tgctttgctt ttggtgttta ttgtggaaga
    21241 gttgtttaaa gaggaggaaa ttactatcct cgaaatgggt tctgggatgg gaattctagg
    21301 cgctactttc ttgacctcgc ttgataaaaa ggtggattac ttgggaatgg aagtggatga
    21361 tttactgatt gatctggcag ctagcatggc agatgtaatt ggtttgcagg ctggctttgt
    21421 ccaaggagat gccgttcgtc cacaaatgct caaagaaagc gatgtggtca tcagtgactt
    21481 gcctgtcggc tattatcctg atgatgccgt tgcgtcgcgt catcaagttg cttctagcca
    21541 agaacatact tacgcccatc acttgctcat ggaacaagga tttaagtacc ttaagtcaga
    21601 tggatatgct atttttctag ctccgagtga tttgttgacc agtcctcaaa gtgatttgtt
    21661 gaaagtctgg ttgaaagagg aggcaagtct ggttgctatg attagtctgc ctgaaaatct
    21721 ctttgctaat gctaaacaat ctaagactat ttttatccta cagaagaaaa gtgaaatagc
    21781 agtggagctt tttgtttatc cacttgctag cttgcaagat gcaagtgttt taatgaaatt
    21841 taaagaaaat tttcaaaaat ggactcaagg tactgaaata taaaatagat tttgttataa
    21901 tagttgaaaa cgcttaaaaa ggggtatcat gttatgacaa aaacaattgc aatcaatgca
    21961 ggaagttcaa gcttaaaatg gcaattatac ttaatgccag aggaaaaagt attggcgaaa
    22021 ggcttgattg aacgtatcgg tttgaaagat tcaatttcaa ctgtaaaatt tgacggccgt
    22081 tctgaacaac aaattttgga tatcgaaaat catacacaag ccgttaaaat tttattggat
    22141 gacttgattc gtttcgatat tatcaaggct tatgacgaga ttacaggtgt tggccaccgt
    22201 gttgtagcag gtggagaata tttcaaagaa tcaacagttg ttgagggaga tgttttagaa
    22261 aaagttgaag agttgagttt gttggctcct ctacacaacc cggccaatgc agcaggtgtt
    22321 cgtgccttca aggaattgtt gccagacatt accagtgtag ttgtttttga tacttccttc
    22381 cacacaagta tgccagagaa agcttatcgc taccctctac caacaaaata ttacacagaa
    22441 aacaaggttc gtaaatacgg tgctcatggt acaagtcacc agtttgtagc aggagaagct
    22501 gcaaaactct tgggacgtcc attagaagac ttgaagttaa ttacctgtca tattggtaac
    22561 ggaggctcaa ttacagctgt gaaagccggc aaatctgtag acacttctat ggggttcact
    22621 cctcttggtg gtattatgat gggaacgcgt acaggggata ttgatccagc tatcattcct
    22681 tatttaatgc aatatacaga ggattttaac acaccagaag atatcagtcg tgttcttaac
    22741 cgtgaatcag gtcttttggg agtttctgct aattctagcg atatgcgcga tatagaagca
    22801 gctgtagcag aagggaatca cgaggctagc ttggcttatg aaatgtatgt tgaccgtatc
    22861 caaaaacata tcggtcagta ccttgcagtg ctaaatggaa cagatgccat tgttttcaca
    22921 gcaggtgtcg gtgaaaatgc agagaatttc cgtcgtgatg taatctcagg gatttcgtgg
    22981 tttggttgtg atgttgatga tgaaaagaat gtctttggcg ttacaggaga catctcaaca
    23041 gaggcagcta aaatccgtgt cttggttatt ccaacagatg aagaattagt cattgcccgt
    23101 gacgttgaac gcttgaaaaa ataagtgaaa ctaaaaaaat attcaataca aggagttggg
    23161 aaagttattt ttccagcttc tttttctgat gaaattgtcc aaaaccttgc tatgattggc
    23221 ttttttgaaa aatatggtat aatagtagta atttaataga tggagttgag ttttgaagaa
    23281 aaactttcgt gtaaaaagag agaaagattt taaggcgatt ttcaaggagg ggacaagttt
    23341 tgctaatcgc aaatttgtgg tctaccaatt agaaaaccag aaaaaccatt ttcgagtagg
    23401 tctatcagtt agcaaaaaac tggggaatgc cgtcactaga aatcaaatta agcgacggat
    23461 tcggcatatt atccagaatg caaaagggag tctggtagaa gatgtcgact ttgttgtcat
    23521 tgctcgaaaa ggagtcgaaa ccttgggata cgcagagatg gagaaaaatc tactccatgt
    23581 attaaaatta tcaaagattt accgggaagg aaatgggagt gaaaaagaaa ctaaagttga
    23641 ctagtttgct aggactgtct ctgttaatca tgacagcctg tgcgactaat ggggtaacta
    23701 gcgatattac agccgaatcg gctgattttt ggagtaaatt ggtttacttc tttgcggaaa
    23761 tcattcgctt tttatcgttt gatattagta tcggagtggg gattattctc tttacggtct
    23821 tgattcgtac agtcctcttg ccagtctttc aggtgcaaat ggtggcttct aggaaaatgc
    23881 aggaagctca gccacgcatt aaggcgcttc gagaacaata tccaggtcga gatatggaaa
    23941 gcagaaccaa actagagcag gaaatgcgta aagtatttaa agaaatgggt gtcagacagt
    24001 cagactctct ttggccgatt ttgattcaga tgccggttat tttggccctg ttccaagccc
    24061 tatcaagagt tgacttttta aagacaggtc atttcttatg gattaacctt ggtagtgtgg
    24121 atacaaccct tgttcttccg attttagcag cagtattcac ctttttaagt acttggttgt
    24181 ccaacaaagc tttgtctgag cgaaatggcg ctacgactgc gatgatgtat gggattccag
    24241 tcttgatttt tatctttgca gtttatgcgc caggtggagt cgccctatac tggacagtgt
    24301 ctaatgctta tcaagtcttg caaacctatt tcttgaataa tccattcaag attatcgcag
    24361 agcgcgaggc cgtagtacag gcacaaaaag atttggaaaa tagaaaaaga aaagccaaga
    24421 aaaaggctca gaaaacgaaa taaataagga ggaatctggt aatggtagta tttacaggtt
    24481 caactgttga agaagcaatc cagaaaggat tgaaagaatt agatattcca agaatgaagg
    24541 ctcatatcaa agtcatttct agggagaaaa aaggctttct tggtctattt ggtaaaaaac
    24601 cagcccaagt ggatattgaa gcgattagtg aaacgactgt tgtcaaagca aatcaacagg
    24661 tagtaaaagg cgttccgaaa aaaatcaatg atttgaacga gcctgtgaag acggttagtg
    24721 aagaaaccgt tgaccttggt catgtagttg atgctattaa aaaaatagag gaagaaggtc
    24781 aaggtatttc tgatgaagtc aaggctgaaa tcttaaaaca tgaaagacat gccagcacta
    24841 tcttagaaga aactggtcac attgagattt taaatgaact tcaaatcgag gaagcgatga
    24901 gggaagaagc aggcgctgat gaccttgaaa ctgagcaaga ccaagctgaa agtcaagaac
    24961 tagaagactt gggcttgaaa gttgaaacga actttgatat tgaacaagta gctacggaag
    25021 taatggctta tgttcaaacg attattgatg acatggatgt tgaggctaca ctttcaaatg
    25081 attataaccg tcgtagcatc aatttgcaaa ttgatactaa cgaaccaggt cgtattatcg
    25141 gctaccatgg taaagtcttg aaggccttgc aactgttggc tcaaaattat ctttacaact
    25201 gctattcaag aaccttctat atcactatta atgtcaatga ttatgttgaa caccgtgcag
    25261 aagtcttgca gacctatgcg caaaaattgg cgattcgtgt tttagaagaa ggacgcagtc
    25321 atcaaacaga tccaatgtcg aatagtgaac gcaagattat ccaccgtatt atttcacgta
    25381 tggatggcgt gaccagttac tctgaaggtg atgagccaaa tcgctatgtc gttgtagata
    25441 cagaataagt aaaatcaggg ttgacctgat tttttgctag ctagaggagg ttaaactgat
    25501 gttgaataag ataagagact atctagactt ttctggtttg cagtaccgta gtcctgataa
    25561 agcgggagca gagcgagaga agatgctggc attccgtcac aaaggacaag aggcccgaaa
    25621 ggcttttaca gaactggcca aagcctttca agcaagccat ccagaatggc aactccaaca
    25681 gactagtcag tggatgaatc aggcccagcg tttgagacca catttttggg tttatctaca
    25741 gagagacgga caagtgacag aacctatgat ggccttacgt ttgtatggga catctactga
    25801 ctttggaatt tctttggaag tcagtttcat cgaacgtaag aaggatgagc aaactttaga
    25861 gaaacaggcc aagattttag acattccaac cgttaaagga atttattatc tagcctactc
    25921 tgatggccaa agtcaacggt gggaggcgaa cgaagaaaag cgtcgtactt tacgcgagaa
    25981 ggtgagaagt caagaagttc gaaaagtttt agtgaaggta gatgttccta tgacagaaaa
    26041 ttcgtctgaa gaagaaatcg tagaaggctt attgaagtct tattctaaaa ttcttcccta
    26101 ttatctagct acgagaaaat aagataattt gtaaaacatc ataaatcata cagtccaaga
    26161 gtgaacagtc cgctgtgtaa ttcttggtct ttttgtttgc gctttcgcat tatataataa
    26221 acttacaaaa acaattcaaa aggagaacaa ttatggaagt catttcaagt gttctaaatt
    26281 ggttttctag caatattttg cagaatcccg catttttcgt aggtttattg gtgttgatag
    26341 gatatgcact tttgaaaaaa cctgcccatg acgttttttc agggtttgtt aaagcaacag
    26401 tagggtatat gttgcttaac gtgggtgctg gtggtttggt tacaaccttt cgtccaatct
    26461 tagcagctct taactacaaa ttccaaattg gtgcagcggt tatcgaccct tactttggac
    26521 ttgctgcagc aaacaacaaa attgcagcag agtttccaga ttttgttgga actgcaacta
    26581 cagctctatt gattggtttt ggaataaata tcttgctcgt agctcttcga aagattacga
    26641 aggtaagaac cctctttatt actggtcaca tcatggtaca acaagctgca acagtatctc
    26701 ttatggttct attcttagta ccacaattgc gcaatgctta cggtacagca gcgattggta
    26761 tcatctgtgg actttactgg gcagttagtt caaatatgac tgttgaggca actcaacgct
    26821 tgactggtgg tggcggattt gcgattggtc accaacagca atttgcaatc tggtttgtag
    26881 ataaagtagc aggacgcttt ggtaagaaag aagaaagttt agacaatctt aaattaccta
    26941 agttcctctc aatcttccac gatacagttg ttgcatctgc taccttgatg ctcgtattct
    27001 tcggagccat tcttttaatc ttgggtccag acattatgtc taataaagaa gtcatcactt
    27061 caggaactct attcaatcct gctaaacaag atttctttat gtacattatc caaacagcct
    27121 ttaccttctc agtttacttg ttcgttttga tgcaaggtgt ccgaatgttc gtatctgagt
    27181 tgacaaacgc cttccaaggt atttcaaaca aattgttgcc aggttcattc ccagcggttg
    27241 acgttgcagc ttcttatgga tttggttctc caaatgctgt cctgtcagga tttatctttg
    27301 gtttgattgg tcaattgatt acaattgttt tgctcatcgt ctttaaaaat ccgattctta
    27361 ttattacagg atttgtacca gtgttctttg acaatgcagc cattgcggtc tacgctgata
    27421 aacgcggcgg atggaaagcg gctgttatcc tttcctttat atcaggtgtc cttcaagttg
    27481 ctctaggagc tctttgtgtg gcccttctcg atttggcatc ttatggtggc taccatggaa
    27541 atatcgactt tgaattccca tggcttggat ttggatatat cttcaaatac cttggtattg
    27601 ttggttatgt acttgtgtgt ctcttcttgc ttgttattcc tcaacttcaa tttgccaaag
    27661 caaaagataa agagaaatat tacaacggtg aagttcaaga agaagcttag tatctagaaa
    27721 aggagaaata aaatggttaa agtattagca gcgtgcggaa atggaatggg ttcatcaatg
    27781 gttatcaaga tgaaggttga aaatgctctc cgtaagctta atcaaacaga ttttacagtc
    27841 aattcatgca gtgtcggtga agctaaaggt ttagcagtag gatatgacat cgtaatcgct
    27901 tctcttcatt tgattcaaga attggaaggg cgaactaatg ggaagttaat tgggcttgat
    27961 aacttgatgg atgataaaga aatcaccgaa aaactcagtc aagcactaca gtaaaaggtt
    28021 ggagggggct ggacagaaac tgagagttat cgtttctgtc cttctccctc tttaaataaa
    28081 ggaggcagat atgaatttaa aacaagcttt aattgacaac gactcgatcc gactaggttt
    28141 agaggctaac gattggaaag aagcagtcaa ggtagcagta gatcccttga ttgaaagtgg
    28201 ggcaattttg ccagagtatt acgatgctat cattgaatcg actgaagagt atgggcctta
    28261 ctatatcttg atgccaggta tggctatgcc ccacgctaga cctgaagctg gtgtgcaaag
    28321 tgatgccttt tcattaatta ccttacaaaa tcctgttgta ttttcagatg ggaaagaggt
    28381 atctgttttg ttggcactag cagcaacaag ttcaaaaatt cacacaagtg tagccattcc
    28441 acaaattatt gccctgtttg aattagaaga ttctattgca cgtttacagg cttgccagac
    28501 taaagaagat gtcttggcta tgattgaaga atctaaggat agcccttatc tcgaaggatt
    28561 ggatttggaa agttagaaag aggaataaag aaatgacaaa aagaatacct aatttacaag
    28621 ttgcattaga ccattcagac ttgcaaggag cgattaaagc agctgtttct gttggtcagg
    28681 aagtagatat tatcgaagct ggaactgttt gcttgcttca agttggaagt gaactggctg
    28741 aagtcttgcg tagccttttc ccagataaga ttattgtggc agacacaaaa tgtgctgatg
    28801 ctggtggaac agttgctaaa aataatgcgg ttcgtggagc agactggatg acttgtatct
    28861 gttgtgcaac catccctact atggaagcag ctctaaaggc tatcaagact gaacgaggag
    28921 aacgaggcga aatccagatc gagctttatg gcgattggac ttttgaacaa gctcagcttt
    28981 ggctagatgc aggtatctca caagctattt atcaccaatc tcgtgatgct cttcttgctg
    29041 gtgaaacttg gggtgaaaaa gaccttaata aggttaaaaa actcattgac atgggcttcc
    29101 gtgtatctgt aacaggtggt ctagatgtag atactctcaa actctttgaa ggtgttgatg
    29161 tctttacctt tatcgcaggt cgtggaatta cagaggctgt ggatccagca ggagcagcgc
    29221 gtgccttcaa ggatgaaatc aaacgaattt gggggtaaat catggtacgt ccaattggaa
    29281 tttatgaaaa ggcaacccca acacacttta cttggctaga acgtttaaat tttgccaagg
    29341 agttaggctt tgattttatc gagatgtcta ttgacgaacg tgacgagcgt ttagcaagac
    29401 ttgactggag taaggaagaa cgcttggaag ttgtcaaaga aatctatgaa actggtgttc
    29461 gtattccttc tatctgtttt tcaggccatc gtcgctaccc attgggatca aaagattcag
    29521 ttctagagga aaaatctcta gaactcatga aaaaatgtat cgaattagct caagacttgg
    29581 gagttcgtac gattcaatta gctggttacg atgtttacta tgaggaaaag tcaccccaga
    29641 cacgccaacg ttttatcaaa aatttgagaa aagcctgtga ctgggctgaa gaagctcagg
    29701 tggtacttgc tattgaaatt atggatgatc ctttcatcag tagcatcgaa aaatatttgg
    29761 ctatagaaaa agagattgac tctcccttcc tctttgtata tccagatatt ggtaatgtgt
    29821 ctgcatggca taatgatatc tatagtgagt tttatcttgg tcatcatgcc atcgcagctc
    29881 tccatctcaa ggatacttat gcagtgacag aaagttcaaa gggccagttc cgagatgtac
    29941 ctttcgggca aggttgtgtc aaatgggaag aagctttcga tattttaaag gaaaccaatt
    30001 ataatggacc tttcctaatc gaaatgtggt ctgaaaattg tgaaacagta gaagaaacac
    30061 gcgcagccat tcaagaggcg caagcttttc tctatccact cattaagaaa gcaggtttga
    30121 tgtaagatga atcaagtaat caatgctatg cgtaaacgag tctgtgatgc caatcaatca
    30181 ttgccaaaac atggacttgt caaatttacc tgggggaatg tatctgaagt taatcgcgaa
    30241 ctcggtgtca ttgttatcaa accatcaggc gtggattatg acgaattgac acctgaaaac
    30301 atggtagtga ctgatctaga tggtaagatc ctagaagggg atttaagacc atcttccgac
    30361 ctcccaactc atgtgcaatt atataaggct tggtcagaaa ttggtagtgt ggttcacacc
    30421 cattcgacag aagctgttgg ttgggctcag gcaggtcgtg atattccttt ctacggaaca
    30481 acccatgcag attatttcta cggttcaatc ccttgcgccc gtagtttgac caaggacgaa
    30541 gtagaagtgg cctatgaaaa agatactggc ctggttatcg tagaagagtt tgaacatcgc
    30601 ggacttaacc cggttgaagt accaggaatt attgtacgca atcacggtcc attcacctgg
    30661 ggcaaaaatc cagagaatgc tgtttatcac tctgtcgtac tagaggaagt atcaaagatg
    30721 aatcgcttta cagaacaaat caatccaaga gttggacctg ctccccagta catactagaa
    30781 aaacactacc aacgtaaaca tggaccaaat gcttattatg gtcaaaagta agaacgatga
    30841 aggaggagaa aaagataaat ttagctcctc tttttacatt tgatttttat tgagagtaaa
    30901 gttggaattg aagtaatttt aaaagatttt ttagaaatag cgcttgatat atatatggta
    30961 aaataaaaag aattgctgtg atatcaatag atttggggga ttttttaata tggtactgga
    31021 taaggcaagt tgtgatttgc ttcaatattt gatggatcaa gaaacgtcca aaacgattat
    31081 ggcgatttcg aaagatttga aagagtcaag aaggaaaatt tattatcaca ttgacaaaat
    31141 caatgctgct ctgggtgacg aggcgcttca catcattagt attccacgaa ttggtattca
    31201 cttaacggaa gagcagagag atgcttgttg taaactatta tcggaagtag attcgtacga
    31261 ttatatcatg agtgcgcatg aacgtatgat gataatgtta ctatggatag gtatttctaa
    31321 agaacgtatt acgattgaaa aattgataga gttaacagag gtatctagga atactgttct
    31381 caatgatttg aatagtattc gttatcaact aactttggaa caatatcagg tgatcttgca
    31441 agtgagcaag tcacagggat accaccttca tgcccaccct cttaataaaa ttcagtatct
    31501 tcaatcgctt ctatatcata tttttatgga agaaaatgcc acttttgtat ctattttaga
    31561 agataagatg aaagagaggt tagatgatga gtgtttgctt tctgttgaaa tgaaccaatt
    31621 ttttaaggaa caggttcctt tagttgaaca agatttaggg aagaaaataa accatcatga
    31681 aataactttt atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca
    31741 gtatcaagaa agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga
    31801 gtatcaggtg tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc
    31861 aggacttgaa gtttctcttg tagctgttct cctcctctcc tatcgtaaag atttggatat
    31921 tcatgcagaa agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta
    31981 ttttgaatca caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat
    32041 gatccactgt aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct
    32101 aacaaaacaa attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga
    32161 aattttagaa ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat
    32221 tcatattgga ggatttttaa aatatacacc atcgtctcaa aaaaatatga aaaaagttta
    32281 tctcgtttgt gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta
    32341 ttttccaaat gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga
    32401 tattgcacaa gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat
    32461 tttaagggtt aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa
    32521 acacaatata tttcgtaata agagcaaaag tttcagtgaa aatctttcta gtcttatttc
    32581 gtcttatatt gtagacagca agttggctag taagttccaa gaagaggttc aaacacttat
    32641 aaatcaagaa atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg
    32701 aacacaaacc tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct
    32761 caaagataac aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag
    32821 agagtcatgg attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga
    32881 agaagaagtc gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg
    32941 gattaagaca ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc
    33001 aaccaaaaaa gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg
    33061 taagttgcaa ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga
    33121 actagactat tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc
    33181 agcaattctc aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg
    33241 acgaatctgg gaaggatggg gtgttccaaa agaacgtatc atcgttgtta aaccaggtga
    33301 cactatcgaa ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt
    33361 ggtaactctc ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt
    33421 tacagatgaa gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac
    33481 catctatcat ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt
    33541 taaaattgat gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat
    33601 gacatctatc gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt
    33661 tcactatgat atctggtcta acttcatggc ttctactaat gagattctag aactttggaa
    33721 aatgcgaaaa gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa
    33781 gtacacttat cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga
    33841 ttgttttgaa caagactcta acattcaatt taaagctttg ctataatata aaaatattct
    33901 ttggaggtta tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat
    33961 gtgtgattca ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat
    34021 gcaattcgtt ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg
    34081 gttatgggag cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca
    34141 gctcaaccaa actggattaa ccgcgaccgc tttattcttt cagcaggtca tggttcaatg
    34201 ctcctttatg ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag
    34261 agtttccgtc aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg
    34321 attgatgcta cgacaggtcc tctagggcaa ggtatttcaa ctgctactgg ttttgcccaa
    34381 gcagaacgtt tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat
    34441 acttacgtta tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca
    34501 tacgcaggtt tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac
    34561 ttggatggtg agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac
    34621 ggttggcata ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc
    34681 gaaacagcaa aagcttcagg caagccatct ttgattgaag tgaagacggt tattggatac
    34741 ggttctccaa acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa
    34801 actgcatcaa ctcgtcaagc cctcggttgg gactacgaac catttgaaat tccagaacaa
    34861 gtatatgctg atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg
    34921 actaaattag ttgcagatta taaagaagct catccagaac tggctgcaga agtagaagcc
    34981 atcatcgacg gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat
    35041 ggtttttctc aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa
    35101 ttaccaacct ttctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag
    35161 acggatggac ttcaagacga tgccaatcgc ttgaatcgta acattcagtt tggtgttcgt
    35221 gaatttgcaa tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac
    35281 ggtggaactt tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta
    35341 caaggacttc ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt
    35401 ccgactcacg aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt
    35461 ttccgtccag cagatgcgcg tgaaacgcaa gcagcttggt accttgcagt gacaagtgag
    35521 aaaacaccaa ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac
    35581 ttcgacaagg ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc
    35641 atcttgattg cgacaggttc agaggttaat cttgctgtct cagctgctaa agaattggct
    35701 agtcaaggcg aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa
    35761 gatgcagctt acaaggaaga aattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa
    35821 atgggtgcaa gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt
    35881 gataccttcg gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgta
    35941 gaaaatcttg taaaaattgt tcgaaacttg aaataatcct aaaaatcagg gcgtaagctc
    36001 tggtttttct taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata
    36061 gtagtcctat gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca
    36121 tgcttgtagg tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc
    36181 aaaagcgtat ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg
    36241 gactttatgg aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag
    36301 atggagttta cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa
    36361 cagcttcact agaaggcgca attgaaaaat aagacgggat cacgaactcc cgtttttcta
    36421 taaaagaaag gaaatgggat gaaaaaatta gtctttgtct gtctgggaaa tatttgccgt
    36481 agccctatgg ccgagtttgt tatgaaatca atgacagata actacgaaat ccaaagtcga
    36541 gcaacttcct cttgggaaca tggcaatccg attcataagg ggactcaggg aatttttcaa
    36601 cagtatgaga ttctttatga caagaacaag acatcgcttc agattagtaa ggaagatttt
    36661 gaagcctttg attatattat cggaatggac gcttcaaata tttctgactt acgtcagatg
    36721 tgtccagtag actgtcaaga taagatttac tcattttcat ctgaaagtgt tccagaccct
    36781 tggtatacag gagattttga agaaacctat cgacgtgttc aagagggctg tcaagcttgg
    36841 ttagaacgtt tagaaaagga gagttaaggt ggaaaatctt acgaattttt acgaaaagta
    36901 tcgtgtctat ctgactcgtc cacgtttaga gcttttggca gtagttacca ttgttttctg
    36961 tgctgtactc gtcttttttc taaatattcc aggaaaaggt gtcttaaaac tcgataatgg
    37021 aacgattgtt tatgatggca gtcttgtccg tggtaaaatg aatggtcaag gtaccattac
    37081 cttccaaaat ggagaccaat atacaggtgg cttcaacaat ggagccttca acggaaaagg
    37141 tacctttcaa tctaaagaag gctggaccta cgaaggtgat tttgtaaatg gtcaggctga
    37201 aggaaaaggg aaactaacaa cagaacaaga agtcgtttat gaaggaactt ttaaacaagg
    37261 cgtttttcaa caaaaataaa gcctccttat ccaaaggagg tattattaga accacaaggt
    37321 aagcgcttac ctgtaaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat
    37381 aaaaaatatt tgaaataaat ttcacaaact tcaaagataa aacctgataa gaaaagaaaa
    37441 tgagaaaagt ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37501 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37561 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37621 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37681 gcgtaaattg gatcaagagc aagttgacta catcgttgct aaagcatcag tagcagcttt
    37741 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37801 agataaagca actaagaact tgtttgcctg tgaacacgta gtaaacaaca tgcgtcacac
    37861 taagacagtt ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc
    37921 agttggtgtt gtttgtggta ttactccaac aacaaaccca acatcaacag caatcttcaa
    37981 atcattgatt tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca
    38041 agaatcatct gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    38101 tgaaaactgt gtgcaatgga ttactcaacc atctatggaa gcaacaagtg cccttatgaa
    38161 ccacgaaggt gttgcgacaa tccttgcaac aggtggtaat gccatggtta aggcggctta
    38221 ttcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38281 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38341 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38401 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38461 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38521 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38581 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38641 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38701 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38761 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38821 ctcaccttct acttttggtg gtattgggga cgtttacaat gccttcttgc catcattgac
    38881 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38941 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    39001 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    39061 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    39121 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    39181 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39241 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39301 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39361 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39421 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39481 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39541 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39601 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39661 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga
    39721 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39781 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39841 tgccatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39901 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39961 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    40021 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    40081 atggaaagaa cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc
    40141 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    40201 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40261 actcaatttg agggaaagat ccagtaattt ttctatgata aaaggcatcc tatcaaggtt
    40321 tttgaacacc tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa
    40381 actagaatag aaacaaaata tataatagat tgaaactaga atagtacaca tctgcttcta
    40441 aaacattgtt agaattcgat ttgactgtcc tgatcg
//
LOCUS       DAVKUR010000013        36746 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKUR010000013 DAVKUR010000000
VERSION     DAVKUR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.013"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            133..1362
                     /gene="arcA"
                     /locus_tag="VW749_000800"
     CDS             133..1362
                     /gene="arcA"
                     /locus_tag="VW749_000800"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0174865.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            1420..2436
                     /gene="argF"
                     /locus_tag="VW749_000801"
     CDS             1420..2436
                     /gene="argF"
                     /locus_tag="VW749_000801"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0174866.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            2601..3548
                     /gene="arcC"
                     /locus_tag="VW749_000802"
     CDS             2601..3548
                     /gene="arcC"
                     /locus_tag="VW749_000802"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0174867.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            3759..5270
                     /locus_tag="VW749_000803"
     CDS             3759..5270
                     /locus_tag="VW749_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0174868.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            5292..6623
                     /locus_tag="VW749_000804"
     CDS             5292..6623
                     /locus_tag="VW749_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0174869.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEENLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            6718..6845
                     /locus_tag="VW749_000805"
                     /pseudo
     CDS             6718..6845
                     /locus_tag="VW749_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(7010..7300)
                     /locus_tag="VW749_000806"
     CDS             complement(7010..7300)
                     /locus_tag="VW749_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174870.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(7288..7539)
                     /locus_tag="VW749_000807"
     CDS             complement(7288..7539)
                     /locus_tag="VW749_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0174871.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            7743..7820
                     /locus_tag="VW749_000808"
                     /pseudo
     CDS             7743..7820
                     /locus_tag="VW749_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7938..8822)
                     /locus_tag="VW749_000809"
     CDS             complement(7938..8822)
                     /locus_tag="VW749_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0174872.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(8967..10118)
                     /locus_tag="VW749_000810"
     CDS             complement(8967..10118)
                     /locus_tag="VW749_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0174873.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(10264..12030)
                     /locus_tag="VW749_000811"
     CDS             complement(10264..12030)
                     /locus_tag="VW749_000811"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0174874.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(12087..15203)
                     /locus_tag="VW749_000812"
     CDS             complement(12087..15203)
                     /locus_tag="VW749_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0174875.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(15213..17507)
                     /locus_tag="VW749_000813"
     CDS             complement(15213..17507)
                     /locus_tag="VW749_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0174876.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRV
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(17566..18366)
                     /locus_tag="VW749_000814"
     CDS             complement(17566..18366)
                     /locus_tag="VW749_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0174877.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(18363..19136)
                     /locus_tag="VW749_000815"
     CDS             complement(18363..19136)
                     /locus_tag="VW749_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0174878.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(19161..19631)
                     /locus_tag="VW749_000816"
     CDS             complement(19161..19631)
                     /locus_tag="VW749_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0174879.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(19622..20053)
                     /locus_tag="VW749_000817"
     CDS             complement(19622..20053)
                     /locus_tag="VW749_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0174880.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(20046..20486)
                     /locus_tag="VW749_000818"
     CDS             complement(20046..20486)
                     /locus_tag="VW749_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0174881.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(20498..21136)
                     /locus_tag="VW749_000819"
     CDS             complement(20498..21136)
                     /locus_tag="VW749_000819"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0174882.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(21251..22654)
                     /locus_tag="VW749_000820"
     CDS             complement(21251..22654)
                     /locus_tag="VW749_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0174883.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELNSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            22830..23603
                     /locus_tag="VW749_000821"
     CDS             22830..23603
                     /locus_tag="VW749_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0174884.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(24774..26279)
                     /gene="adcA"
                     /locus_tag="VW749_000822"
     CDS             complement(24774..26279)
                     /gene="adcA"
                     /locus_tag="VW749_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0174885.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(26289..27095)
                     /locus_tag="VW749_000823"
     CDS             complement(26289..27095)
                     /locus_tag="VW749_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0174886.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(27088..27792)
                     /locus_tag="VW749_000824"
     CDS             complement(27088..27792)
                     /locus_tag="VW749_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0174887.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(27792..28232)
                     /gene="adcR"
                     /locus_tag="VW749_000825"
     CDS             complement(27792..28232)
                     /gene="adcR"
                     /locus_tag="VW749_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0174888.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(28387..29655)
                     /gene="dltD"
                     /locus_tag="VW749_000826"
     CDS             complement(28387..29655)
                     /gene="dltD"
                     /locus_tag="VW749_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0174889.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(29648..29887)
                     /gene="dltC"
                     /locus_tag="VW749_000827"
     CDS             complement(29648..29887)
                     /gene="dltC"
                     /locus_tag="VW749_000827"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0174890.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(29901..31145)
                     /gene="dltB"
                     /locus_tag="VW749_000828"
     CDS             complement(29901..31145)
                     /gene="dltB"
                     /locus_tag="VW749_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0174891.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(31142..32692)
                     /gene="dltA"
                     /locus_tag="VW749_000829"
     CDS             complement(31142..32692)
                     /gene="dltA"
                     /locus_tag="VW749_000829"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0174892.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(32713..32844)
                     /locus_tag="VW749_000830"
     CDS             complement(32713..32844)
                     /locus_tag="VW749_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0174893.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(33158..34336)
                     /locus_tag="VW749_000831"
     CDS             complement(33158..34336)
                     /locus_tag="VW749_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0174894.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(34788..36064)
                     /gene="ltrA"
                     /locus_tag="VW749_000832"
                     /pseudo
     CDS             complement(34788..36064)
                     /gene="ltrA"
                     /locus_tag="VW749_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        11193 a         7763 c         6354 g        11436 t
ORIGIN      
        1 tgctaaatat tataatttat attattttcc gagaaattat agccattgac attacctagg
       61 aattgcgtta taacatacat gtaagcggta cccaaaatgg tgccaagtca aaatttttaa
      121 ggaggaaaat acatgtcttc acatccaatt caggtcttct cagaaattgg gaaactgaaa
      181 aaagttatgt tacaccgtcc aggcaaggag ttagaaaact tgttgccgga ctatcttgaa
      241 aggcttcttt ttgatgatat tcctttcttg gaagatgctc aaaaagaaca tgatgcattt
      301 gcccaagctc ttcgcgatga aggaattgag gttctctacc tagaacaact cgctgctgaa
      361 tcattgacct ctccagaaat ccgcgatcaa tttatcgagg aatacttaga cgaagccaac
      421 atccgtgatc gtcaaaccaa ggttgctatt cgtgaattgc ttcacggcat caaggacaac
      481 caagaattgg ttgaaaaaac aatggctggg attcaaaaag ttgaattgcc agaaattcct
      541 gacgaagcta aagatctaac tgacttagtt gaatcagatt atccatttgc aattgacccg
      601 atgccaaacc tctatttcac tcgcgaccca tttgcaacaa ttggaaacgc cgtatcgctt
      661 aaccacatgt ttgcagacac tcgtaaccgt gaaacactct acggtaagta tatcttcaaa
      721 taccacccaa tctatggcgg aaaagtggat ttggtctaca accgtgaaga agatacgcgt
      781 atcgaaggtg gagacgagct agttctttct aaagacgtcc ttgcagtagg tatctctcaa
      841 cgtacagacg cagcttctat cgaaaaactt ttggtcaaca tcttcaagaa aaatgttggc
      901 ttcaagaaag ttttggcctt tgaatttgct aacaaccgta aattcatgca cttggatact
      961 gtcttcacta tggtagacta tgacaagttc actattcacc cagaaatcga aggcgacctt
     1021 cacgtttact cagttactta cgaaaacgaa aaacttaaaa tcgttgaaga gaaaggtgac
     1081 ttagctgaac ttcttgctca aaaccttggt gtagaaaaag ttcatttgat tcgttgcggt
     1141 ggtggcaata tcgtagcagc tgcgcgtgaa caatggaacg acggttctaa cactttgacc
     1201 atcgcacctg gtgtggtagt tgtttatgac cgcaataccg tgaccaataa gattttggaa
     1261 gaatacgggc ttcgcttgat taagattcgc ggaagtgaat tggttcgggg ccgtggtgga
     1321 cctcgttgta tgtctatgcc atttgaacgt gaagaagtgt aatcgctgtt cggcattcgt
     1381 caatagaaaa tgtaaaaaat agaaagagga aataataaaa tgacaaattc agtattccaa
     1441 ggacgcagct tcttagcaga aaaagacttt acccgtgcag agttagaata ccttattggt
     1501 ctttcagctc acttgaaaga tttgaaaaaa cgcaatattc aacaccacta ccttgctggc
     1561 aagaatatcg ctctcctatt tgaaaaaaca tctactcgta ctcgtgcagc ctttacaact
     1621 gcggctatcg accttggtgc tcacccagaa tacctcggag caaatgatat tcagttgggt
     1681 aaaaaagaat ctactgaaga tactgctaaa gtattgggac gtatgtttga cgggattgaa
     1741 ttccgcggat tcagccaacg tatggttgaa gaattggcag aattctcagg cgttccagta
     1801 tggaacggtc taactgacga atggcaccca actcaaatgc tcgctgacta cttgactgtt
     1861 caagaaaact tcggtcgctt ggaaggcttg acattggtat actgtggtga tggacgtaac
     1921 aacgttgcca acagcttgct cgtaacaggt gctatccttg gtgtcaatgt tcacatcttc
     1981 tcaccaaaag aactcttccc agaaaaagaa atcgttgaat tggcagaagg atttgctaaa
     2041 gaaagtggcg cacatgttct catcactgaa gatgctgatg aagcagttaa agatgcagac
     2101 gttctttaca cagacgtttg ggtatcaatg ggtgaagaag acaaattcgc agaacgtgta
     2161 gctcttctta aaccttacca agtcaatatg gacttagtta aaaaagcagg caatgaaaac
     2221 ttgatcttcc tacactgctt gccagcattc cacgatactc acactgttta tggtaaagac
     2281 gttgctgaaa aatttggtgt agaagaaatg gaagtaacag acgaagtctt ccgcagcaag
     2341 tacgctcgcc acttcgatca agcagaaaac cgtatgcaca ctatcaaagc tgttatggct
     2401 gcgacacttg gtaaccttta tattcctaaa gtataatttt agataataaa ccgtctacca
     2461 acagctatga gggctgcgac taatagcttt agtccggtcc tcttttatgt aatggtaatc
     2521 tattatttct tataaaatat gtgaaaaatc attaaattga aatctaaacg cattctattg
     2581 agtgtgataa aggagaattt atggcaaatc gtaaaattgt agtagctttg ggaggaaatg
     2641 cgattctttc ttctgaccca tcagcaaagg ctcaacaaga agctttagtt gaaacagcta
     2701 agcatcttgt aaaattgatt aaaaatggag atgatctgat tatcactcac ggtaatggac
     2761 ctcaagttgg gaatctcttg ctccaacatt tggcatcaga ctctgaaaag aaccctgcct
     2821 tcccactcga ctcacttgtc gctatgacag aaggtagcat cggtttctgg ttgaaaaatg
     2881 ctttgcaaaa tgctctcttg gatgaaggca tcgaaaaaaa cgttgcctct gttgtaacgc
     2941 aagttgtcgt agataaaaat gatccagctt ttgttaactt gagtaaacca atcggtcctt
     3001 tctattcaga agaagaagca aaagcagaag ccgaaaagag cggagcgact ttcaaggaag
     3061 atgctggccg tggctggcgt aaggtcgttg cctcaccaaa acctgttgac atcaaagaaa
     3121 ttgaaaccat ccgtactctt ttaaatagtg gtcaagtcgt cgtagctgca ggtggtggcg
     3181 gtattcccgt cgtcaaagaa aacaatggac atttgactgg tgtcgaagcg gttattgata
     3241 aagacttcgc ttcccaacgt ttggcagaat tggttgatgc agacctcttc atcgttttga
     3301 caggtgtaga ttatgtattt gttaactaca acaagccaaa ccaggaaaaa ttggaacatg
     3361 tgaatgttgc ccagctggaa gaatatatca aacaagatca gtttgcacca ggtagcatgc
     3421 ttccaaaagt agaagcagct atcgcttttg tcaatggtcg tccagaagga aaagcagtta
     3481 ttacttccct tgaaaatcta ggcgccttga ttgaatctga aagtggaaca attattgaaa
     3541 aaggataagt tgttttacta ataagatgta ttctatttct agtatcttta tatcaaatta
     3601 gaaattattc ttgaaaacat gtacaatatt tcaaaagata ttagtttttt agactttaat
     3661 atggtaaaac aaatataaat agaaagcgtt ttcttaaatg tttatttaag aaagtagttg
     3721 gttttttaca ctttgttaga catcaggagg aaaaacaaat gagtgaaaaa gctaaaaaag
     3781 ggtttaagat gccttcatct tacaccgtat tattgataat cattgctatt atggcagtac
     3841 taacttggtt tatccctgcg ggggccttta tagaaggtat ttacgagact cagcctcaaa
     3901 atccacaagg gatttgggat gtcctcatgg caccaattcg ggctatgcta ggtactcatc
     3961 cagaggaagg ttcgctcatt aaagaaacga gcgcagcgat tgatgtagcc ttcttcatcc
     4021 ttatggttgg tggtttcctt ggcattgtca acaaaactgg tgctcttgac gtagggattg
     4081 cctctatcgt gaagaagtat aagggccgcg aaaaaatgtt aattttggta ctaatgcctt
     4141 tgtttgccct cggtggtaca acttatggta tgggtgaaga aacaatggcc ttctatccac
     4201 tccttgtgcc agttatgatg gccgttggtt ttgatagcct gactggtgtt gcaattattt
     4261 tgctcggttc tcaaatcggc tgtttggcat ctactctgaa tccatttgcg acaggtattg
     4321 cttcagcgac tgcgggagtt ggtacagggg acggtatcgt acttcgtctg atcttctggg
     4381 ttaccttgac tgctcttagt acttggtttg tttaccgtta tgcggataag attcaaaaag
     4441 atccgactaa gtcactggtt tatagtactc gcaaagaaga tttgaaacac tttaacgtag
     4501 aagaatcttc atctgtagaa tctacactta gcagcaaaca aaaatcagtt ctcttcttat
     4561 ttgtgttgac attcatcttg atggtattga gcttcattcc atggacagac cttggcgtta
     4621 ccatttttga tgactttaat gcttggttga ctggtcttcc agttattggt aatattgtcg
     4681 gttcatctac ttctgcacta ggtacttggt acttcccaga aggcgcaatg ctctttgcct
     4741 ttatgggtat cctgattggt gttatttatg gtcttaaaga agataagatt atctcttcct
     4801 tcatgaatgg tgctgctgac ttgctcagtg ttgccttgat cgtagcgatt gctcgtggta
     4861 ttcaagttat catgaacgac ggtatgatta ccgatacaat cctcaactgg ggtaaagaag
     4921 gcttgagcgg tctatcttca caagtcttta tcgttgtaac ttatatcttc tatctaccta
     4981 tgtcattctt gatcccatct tcatctggtc ttgccagcgc aactatgggt atcatggctc
     5041 cacttggaga atttgtaaat gtccgtccta gcttgattat cactgcttat caatctgctt
     5101 caggtgtctt gaacttgatt gcaccaacat ctggtattgt gatgggagct cttgcacttg
     5161 gacgtatcaa cattggtact tggtggaaat tcatgggcaa actcgtagtc gctattattg
     5221 tagtgaccat cgcccttctt ctccttggaa ccttccttcc attcctataa aatagtgagt
     5281 gaggtgattc catgaaaata gatataacaa atcaagttaa agatgaattt cttatatcat
     5341 taaaaacctt gatttcctat ccttcagtac tcaatgaagg agaaaatgga acaccttttg
     5401 gacaagcaat ccaagatgtc ctagaaaaaa ctttagagat ttgtcgagac ataggtttca
     5461 ctacctatct tgaccctaaa ggttattacg gatatgcaga aatcggtcag ggagcagagc
     5521 ttctggccat tctctgtcat ttggatgttg ttccatcagg tgatgaagca gattggcaga
     5581 caccgccatt tgaagcaact atcaaagacg gctgggtatt cggacgtggt gtccaagatg
     5641 ataaaggccc ttcgctcgca gctctctatg cagtaaaaag cttgctggac caaggtattc
     5701 agttcaaaaa gcgcgtacgc tttatctttg gtaccgatga ggaaaacctc tggcgctgca
     5761 tggcacgcta caataccatc gaagaacagg ccagtatggg ctttgcacct gactcatctt
     5821 ttcctctgac ctatgctgaa aaagggcttc tacaggtcaa acttcatggc ccgggatcgg
     5881 atcaactaga gcttgaagta ggaggcgcct ttaacgttgt accagacaag gccaactacc
     5941 aaggtcttct ctatgaacag gtttgtaacg gtctcaaaga agctggttat gattaccaaa
     6001 ccactgaaca aaccgtaacg gttctcggag tgccaaagca tgctaaggat gctagtcaag
     6061 gtatcaatgc tgtcatccga ctagctacca ttcttgctcc tctccaagaa caccctgctc
     6121 tcagttttct tgcaacacaa gcaggtcaag acggcacagg aagacaaatc tttggtgata
     6181 tagcagatga accttctggt cacctatcct ttaatgtcgc aggtctcatg atcaatcatg
     6241 aacgttctga aatccgtatt gacattcgga ctcctgtctt agctgacaag gaagaactag
     6301 tagagttgct tacaagatgt gcacaaaact accaactccg ctacgaagag tttgactatc
     6361 tagcgcctct atacgtcgca aaagacagta aactcgttag cacactgatg caaatctacc
     6421 aagaaaagac tggcgataac agtcctgcta tttcatccgg tggtgccact tttgctcgca
     6481 ccatgccaaa ttgtgtagcc ttcggcgcct tattcccagg agcgaagcag acagaacatc
     6541 aggcaaatga atgtgccgtt ctagaagatt tgtaccgtgc tatggatatt tatgccgaag
     6601 ccgtctatcg acttgcaact taatcaggca actgtttcta caaaaaaaaa tcgaccgatt
     6661 aatgaactgc accccaaaag ttagacagaa taaatctaac ttttggggtg ttttattatg
     6721 aaattgaatt atgaagataa agttcagatc tatgaactaa gaaagcaagg acaaagcttc
     6781 aaacagcttt caaaaagatt tatgtggatg tttctggttt aaagtcatct gaatctttga
     6841 gatgagcttt ataaatcgct tttttcagtg tttgcactgg tgtttcgata aactcaaact
     6901 ttttagccgt ggtattgcct gattttatag tatattgaaa ctagaatagt acacctctac
     6961 ttctaaaaca tttttagaaa tcgatttgtc ctgttcttat ttcattttac tatatttgag
     7021 ccacttcgtc tttaacggct ttattcataa gctcttgtaa tttttcttta ctatcaatta
     7081 cttctgattt tccgttgtaa tttattgtaa taggttttaa cttacctaat ttctcgacac
     7141 gctcattaat ttgatctttt ttgaaggctg catatgtttt tcctaagatt ttttcgaaaa
     7201 tatatttatc agatagcggt ttgccttctt cttcagcttg gtttttgtat tgatttgaaa
     7261 cataaggaac aaatccttca tagtaaccta atgctcccat aagttcaaaa gcttgttttc
     7321 taattcaaac cattgcaact cagatttcag cttttcagat aaatcctgct catccaaata
     7381 atgacttaaa attagtgctg aactcgtttc tgtatcctgt acaggctgat cacccatacc
     7441 atcaaaaaat aaactcgttc ctagcaagac cgaacaagct cctattgcat atggcctcaa
     7501 agaaaaacgc tgctttctct caaattgaaa ttctttcatc ccatctccca tcattcatta
     7561 ttactgtata ttttgtatat cagaaatagt ttgtattcac aaatctttct agttattccc
     7621 ttatcattcc taattaaggg agataacata caataatttt tagttaaatg tatatcgatg
     7681 ttttttgttt ttcttaataa acgcaataca aaaagagcct gttgccaagc tctttgtact
     7741 caatgaaaat caaagagcaa actaggaaac tagccacagg ttgctcaaaa caccgttttg
     7801 aggtagtaga taagactgac gaagtcagct caaaacactg ttttgaggtt gcagatagaa
     7861 ctgacgaagt cagtaacatc tatacggcaa ggcgacgctg acgtggtttg aagagatttt
     7921 cgaagagtat tagtctatta tttcttctca gcgcgaaggg ctgacaagat ttgtgttcgg
     7981 atatcatcca caccatttgg agtatttggt aaaaagatgg tttgatttcc tttagaggca
     8041 aaggtattca aggtatccaa atactggttg gtcaagagga tagacatgat ttgttcttct
     8101 gtcatgccaa cattggcttc cttgagttcg gtgatagact ctgccaatcc atccacaatc
     8161 gccttacgtt gttgggcaat ccccacacca tgaaggcggt ctttttctgc ttcggcttca
     8221 gctgcagtga caattttaat cttgtcagct tccgccaatt cttgtgctgc gacccgctta
     8281 cgttgcgccg cattgatttc attcatggat tgcttaactt ctgcatccgg ttcgactttg
     8341 gtaatcaagg ttttcacgat aatgtagccg taagtggtca tttcttctgc tacttggtgt
     8401 tgaacctcaa gggcaatctc atcttttttc tcaaacaatt catccaaggt taattttgga
     8461 acagaagagc gaagagcatc ttcgatataa gatttaatct gagattctgg acgtatgagt
     8521 ttatagtaag catctgtcac gctctgctcg ttgacacggt actgagtcgc tacattcatc
     8581 ataacgaaca cattgtcctt ggtcttagtc tcaaccacaa tatcactttg caacaagcgc
     8641 aactgaatcc gtgctgcaat cgagtcaatc ccaaaaggca agcgaatatg aataccgcta
     8701 ttagcaacct tttggtattt cccaaagcgt tcaataatcg ccaccgactg ctgacgaacc
     8761 acataaactg tactcagtgt gactatcacc aataggagca cacaaacaat cagaaaaatc
     8821 atgaaaaata ttgccataat ggaacctcca caagtatttt tctagtatta tagcacattt
     8881 aaagaaggct gtgccgtttt tactgcgatt tttcctgaaa tgtcaataat tagaggtgaa
     8941 ttgtcctatt gtcgtccaat ctcttgctaa aataactctt tataaaaggc aatcgtttct
     9001 tctaaggttg gcataaatgg atttcctggt gcgcaggcat caatcaaggc attcttagaa
     9061 aggtattcaa agtcgaaatc tttttcttca ataccaagtt cagtcagttt cttaggaata
     9121 cctactgtct cagaaagctt ctcaatctca acaatcgcat aatcggcaca ttcttgatct
     9181 gatttacctt ctacatgaag tcccaaggct ttggcaacat tgcggaaagc ttctggtaca
     9241 cgtttagcat tttcacgttc tataactggt agcaacatgg cacagcaaac accatgtggc
     9301 aaattatata ctgcaccgag ttggtgagcc attgagtgaa cataaccaag accagcatta
     9361 ttaaagctca taccaccaag gaagatggca ttgaccatac cttcacgcgc ttcaatatca
     9421 tgtccatttt ctacagcacg aggaagatat tccttgataa gctcaatagc accaatagac
     9481 agtttcttgg ttacatcata agcaccaggt gttaccaaag cttcaacagc gtgagtcaga
     9541 gcatccatac cagtagcagc agtcaggcct ttaggtttgg aaagcatgag ttccgggtca
     9601 ttaacagaga taagagcaag gctattcttg tcaaccatta ccatcttaac cttgcgttct
     9661 tcatcagtaa tcacatagtt aatagtgatt tctgcagaag ttcctgccgt tgtattgata
     9721 gccacaactg gcaagccttt tttagcagac ttatgaagcc cttcataatc ctgtggtttt
     9781 ccaccatttg tagccatgat agaaatacaa ctagctgcat cctgtggaga acccccgcca
     9841 agactgatga taaagtcaca gccatgttct tgcaaagcag ctaccccatc tgtgacattt
     9901 ttacaagtag ggtttggctc tacatcgcta aagatgacat attcgattcc ttctgtatcc
     9961 agtggtttta aaaccttagg taaaatgtca ctgccttcga tgtacttatc tgtcaccaaa
    10021 agtgcctttt tatagccaag ttccttgata taaggaccca cttcatttac aacaccttta
    10081 ccaataaggt tgactgccgg aacataaaat gtagccatat aattttcctc ctgcgcctcc
    10141 gcgctatcta tttaacatca ttatattagt ttttgtattc gttttcaatt atttgtgaat
    10201 tgtttaacaa atctttttaa aaggatagga gggacataag ttcacctcct atatacacaa
    10261 tttttattta tgtagcggtc ccaacaactg acatgcacga tagtctgctg attctagatc
    10321 ttctgttcca aataaggacc aatttttagg tctaaagata tcttcctcgg gtacattatg
    10381 catattgaca ggaattctca acatagaagc caaggtaatc aagtctgctc caatgtgtcc
    10441 atatgttatg gctccgtgat tagctcccca attattcatg acgtcataga cagacttgaa
    10501 agcacctttt cctgtcaaac gtggagcaaa ccaagtagtt ggccatcctg gatctgtacg
    10561 attatctaaa gtatggtgaa catcttcagg aagttcaagt gtataacctt ctgcaatttg
    10621 tagcactgga ccaacccctt ttagaagatt gagacgtacc attgttactg gcatatcccc
    10681 cttcgtcaag aaacgagttg agaatcctcc tccacggaag tattcgcggt ttgctggtgg
    10741 gaagtctgta ttttcaagca tagcctgcac ttcactttct tccaactccc agaatggttt
    10801 cataacaggt ttgccatctc gagtagcttg ccctgtacca tccaatgtac aagaaccaga
    10861 gttgattaga tgtaagaagc cagctgcagc acaaccctct aaagtatgtc ccgttacacg
    10921 tttaacagcc tctggactcc aataagtgcg cacatcagca aagatttgtg gagtatttgt
    10981 taatagataa ttaaagagca tagacacacc atttagtgaa tcattctctg tcgcaaatac
    11041 aaatggtttt cgaataccat tccagtcaaa ctgagtattg aggaaagttt ccataaagtc
    11101 cccatttggg aaatggtctg tccactgacg ttgaccttgg aaaccagcta ctaaagcatg
    11161 gtgaccaact gcttcttcct caaaaccaag ttcagcaagt cttgggttac caaccattaa
    11221 gtcacgtcca atcatgaaca tcttaataac aaattcccat tgtctatctt tttcttcacg
    11281 gcttaaaaca aggtcttcac ggttatggtc gaatccttct tttacgtttt ctttcaccca
    11341 tttgagcgca cgttcgaact cttcagggtc gtaaatacca cggtccatac ggcgtgtgaa
    11401 ctccgtcata tctaccgatt catttcgcat tcctaggtat tcttggaaga aatccggatt
    11461 tacaatagaa ccaccaatcc ccatcgaaac actccccatt gataagtaag ctgtatctct
    11521 catcaagcca gttgcaagag ctgcccgcgc ataacgtaaa agtttttctt tgacatcttc
    11581 tggaatagct gtatcattag cttcctgaac atctctacca taaatcccaa aggctggaat
    11641 ccctttttga gcatgtgaag ctagtacagc tgcaagatag acagctcctg ggcgttctgt
    11701 cccattaaat ccccaaatag catgaggaat atctggagac atatccatag tttcactacc
    11761 ataacaccag catggtgtaa ctgtaattgt tgcgcaaaca tttgattttt taaacaactc
    11821 atgggaagct gcagcctctg gaacacgacc aatggtagat ggagaaatca cacattccac
    11881 aggttcccca tctggatatt tcaatgtgct tgaaatcaaa tctgccacac ttttagccat
    11941 gttcattgtt tgtacttcaa gtgattcgcg tacaccttga cgacgaccat caatagtcgg
    12001 acgaatccca atacgtggat gttgaatcat actattttcc tcttattttt ctgtttcttt
    12061 catactaccg atgataattt ttaaaattac ttataagtat aaacctctac ctctgccaaa
    12121 cttaaaggaa ttcctgcgtt tctcaaagaa attctaacct tttttccctt cagccctttt
    12181 aagtctatgg atagattatt gctttctaaa ctgtcaatat gttgtttaaa aacttcatga
    12241 ttatttgaat catatataat aatatcaaaa tttgataatc tctgaatttc agcatctgtt
    12301 ctattataaa taattaactt ttctaattct tcggtttgtg ctaaatctat ctcccaccat
    12361 gaaggagaat ctcctttggt atgagtcact gaatgatgac cataatctcc gtttttattt
    12421 ccatcaactg ctagacgaga aaaaccattg taatccgttg aactctgtcg agtttctttg
    12481 gttaatgcaa tattagaaag tttcttcgga gttctctttg aaccatagac ttcaacttcc
    12541 gctaaactta acggaatagc tgctgatttt aattctattt tgactagctt agcccctaca
    12601 gaaggtactt ttaaagataa caaaccatca actactttat caaaatgtct tctaaaaact
    12661 tcttctcctg atgaagatag aaaaataaca tcaaaattag ataaacgctg aggttcggca
    12721 tctgttctat tataaatatc aactttagaa accgtaaact cttctcccag atcgacctgc
    12781 caccaagcgt tagaatctgc cttagtatga gtcaccgaat gatgtccgta atctccatct
    12841 ttattaccat caactgctaa agcagctaca ccctcataat tggttgaact ttgagtagct
    12901 accttatttg tagagactac tttatcttct gttattttat ctatatcctc ttcagattgc
    12961 ttaccatctg attctctaaa aacctctact tctgctaaac tcaaaggcac tccactcgtt
    13021 agtaatttaa ctttaatata ccttgctcct ttttctttga aatctagact aacagattca
    13081 cccgacaaat tattaacatg tttcttagca acttcgtttc tattattgtc atatagaatc
    13141 acatcaaaat tagatagacg ttgagtctca gcatctgtgc gattataaat tttaacaagc
    13201 ccaactttat ccattttttt caaatcgact tcccaccaag agggattatc tgccctagtg
    13261 tgtgttaccg aaccagagtt aaaattacca tttctgttac catccacagc tctattaggg
    13321 tctccattgt aatctacaga actttgtgtt gttggttttg catatgctat attcaaatta
    13381 ccatcattaa atttatctgg tgttgggaaa gagactggac ctgtcccctc agtatttata
    13441 gacatctcta ccattccatt atgattaacc gtaatggtat aaacatgggt attctcatcc
    13501 caattttctg tataagtata atgattttta tcgccactta tatttatctg aggtttatga
    13561 ccagtatgcc cttttaatgt aagtgttgtt gtcctaaagt cattatctac aggattgatg
    13621 gaataatttt tgcttatcca gttcgctaac tctaattctt ctttcttcca actttttgat
    13681 gcatcaaaat ttcctgataa tgcccacata gctgtcttat ctgtcctgta attattcaat
    13741 aaaatatgta aattatttgg attttcttta acaacagcgt aagtatgtgg cgtcaaatct
    13801 aacgataacg actttgtatt attagtatac ataggcaaca ttacttgctg atttttattg
    13861 atattagcat tactattata aatataccag gaattaccta cacgctgagc atacccatct
    13921 ccttcataaa gttttggata aagcgagttt aaatagttga ctttactaga caattcctca
    13981 ctatttttag tcaaaatttt tgcattaggg aatatagatg aaatcttttc cttatcaatt
    14041 ttctcatgta ttacaggaag aatatgatat ctcccattat tatataaagg cattgtttca
    14101 tcattcgaat aaagtccttg ataaaatccg tttaatgaac taatcctacc ttctccattc
    14161 caaaatacag cttttgttct atttacaact tcttccttac ttggagctgg attttgtata
    14221 gcatgtctaa agaaaggaat aataccttta gtaaatgctg gagttggtac atcatttgtc
    14281 ataaatgtat acgcggcaca ttcgaaatta taaactgtgc ctcccccagt atatacattc
    14341 atcatttcca tagcaatcat tgattctggt tccgatgcat aggatctcat atccctagct
    14401 cttccagttt caaatgtgtt tgtataatgt ttttcccacc atttccatgt atctgttgat
    14461 gagccccagt tatcacataa gccactcaac caaaatccac taacgataga atctgtaccc
    14521 gcatcatctc ttattggcgt atttttagtt gccaacacca aatttttatg atatttttga
    14581 ctcgcttcaa agaatgtcgg atcattcata atagtttccc agaaccattt ttcatgatca
    14641 tgccagataa aatgcgctcc atatttggca caaacttcca aatatttagc actatgcgga
    14701 gctaactggt tattgtaaat ccaataattc tcaatattta aaacaccttt taacacacta
    14761 tacttttgga attgttcatc taaccactct ggaggaactg tattacgctc tccagccgac
    14821 ataataacca agaaaactgg aatgtttaga ctttgagctt cctccaacat cttgacatac
    14881 cattctctca attctttcgt atctcgtgga atacaacttg ttggtttaca gacttttgca
    14941 ggatgaagtt caatcgctgc atatggtttt acatcttcag gaatagcttc ccatgctccc
    15001 ttcaatgtgt tcccccacca taatccgtta ccattatcat tgccatacaa cggagaaagc
    15061 aacaatggcg attcattatt aatcgtcgtt ctcatttgaa cacgattatc agccttaact
    15121 cctgctaaca atccaaaaca taacatccca atacatacaa acagtattgt gattaatttt
    15181 ctttttattt tttctttatt catgacttat acctaaaaat ttaactcaat aattttttct
    15241 gaattaaata ccaattcaat attttgtaca tcagtatttt tgccatatac tcttactctt
    15301 actttttgat ctttgtttcc tccttccaat tttaggaatg ttatatcccc atttttccaa
    15361 gcaaacgata ccttatatcc tcctcttact ctgaaacctt tcacttctcc ttctgaccaa
    15421 gcagaaggta aagctggaat tagtgataac caattatgat ggctctgtac taataattca
    15481 caaattccac tcaccaaacc taaattacca tcaatttgaa atggtggatg gtcaagaaat
    15541 aaattgccaa gagtcgcatt atttaacaaa ccattaatct ggttataagc aggttcacct
    15601 tgatatagtc tcgcaaaaaa atgaatcagc catgcagcac tccaacctgt ttgtgtacta
    15661 gcatgcaaac cacttactaa ccaattatta atcgcttgct ccctatcctg tgaagataaa
    15721 aagttagcgt ttgataatct tctattgata gtgattttag ctgcttctgc taattccgga
    15781 gttttatgaa tatcaatctc attataagga taaagcccaa atagaggtga aatgtgtcta
    15841 tgaccaggct ctacttcttc ataatcctct agccattctt gtatttgccc attactacct
    15901 atttttgttc taggtaattt cttttttaac tccttcacac gactaataaa atccgaattg
    15961 tctcctaatt gttttgcaat tccaatgcat gaatcacaaa aatatcttaa aatttgatta
    16021 tcaattgtag atgatagaca agcatttcct tcaataccat tttttaagcg atatttattt
    16081 tccggtgaga cacttggacc tgtcatcaag tagccatcca cctcaaataa ataatcttca
    16141 aagaaaagaa atgcttcttt tatcatttca aaatgttccg taagaatacg ctcatcttgg
    16201 aaatataaat agtgttccca aatatgagta cataaccatg gaatagttaa tacccaaatt
    16261 gcagccccca tggcatgaga ttggggagcc gtatcgccaa aaccatccgt attatgatgt
    16321 gctgtaaaac ctctagctcc atacattttc ttagcggtta gtcttcccgg ttctctcatt
    16381 ctttcgagca tatcaaataa tggatattct acttctggta aatcacatgg acctaccatc
    16441 caataattca tttgagtatt aatattaatc gtatatttag aaccccaaat tggatttaat
    16501 tcatcacacc atattccttg aagattggca ggtaaaccat tcggttgact agacgatatt
    16561 aacagatatc ttccataatg aaataacaag ttagtcaagt agttactata ctttttagtg
    16621 ttttcaagaa gtagattcgt tggaatgcta agacaatctt tactatagtc tagtttaaaa
    16681 tcaactctat taaattgctc ctgatatttt tttacatgtt catctttttc tgtaaagtaa
    16741 tcaatactac taaattctcc ctgaagagaa gaaatatcta tatttcccca ataatccgtc
    16801 attgatttga gataaagaaa tacctctgta gcattccgaa taactattgt ctctcccaat
    16861 acacttactt caccatccgt aaccttagaa tgacatacta ctttaaactg aacacctttt
    16921 ctacctccag cagaggccga cattaaaatt gtacttgaat ccagtttaga tacttcatca
    16981 ttaaaccgtt tatttctacc caaattaatg tttaaattta atgtgttttg aactgatgac
    17041 actatacggc aacataaaat attcttatta aaactcgtaa aatattctct ttttatttgt
    17101 aaattacaac tattaggctc aaacacaaca ttagaaatag ctgtatctaa atctagctct
    17161 ctttcataca atgaaagagc acaagactga atatctatat gctcaatgta aagttcccca
    17221 agtaattcat agtggctttg atctcttggg gtagcaaaca ttgttaactt tatcaattct
    17281 tcggctttct gaatttctcc atctaaaaga tattcccgaa tttttttaag atgcaatagt
    17341 gagtctggat tatttctatc tgactttcct ctataccaaa tagtctcatc gtttagttga
    17401 atacattctt ttgtagctga accataaatc ataccaccta aatgaccgtt cccaatcggc
    17461 aaggcttcat tccaatttga ggcagctttc ttataccata atttcactct ttacctctct
    17521 tccaaaatgg aggtgatatc ccaaatacca cctccacact ttctactact tcaaaattcc
    17581 taaaacaact aggataactc caatagccat aacactaaag attagtacaa ccggattctt
    17641 tccttttcta attaatttac acattaataa agtcaaagcc atagggataa atcctggaat
    17701 taattttgta atcatttctt gaacagaaat aacaagttcc ccctgcttaa attctaatcc
    17761 aaaattaata ccaaccattg atggaatcaa accacccact agtactagcc ctaatgctgt
    17821 cgccatactc gtaacgcgat tcaatgttcc ttttgtatta ttttcttgga taagactaga
    17881 acccttagta tacccatatt tcaaaccgaa atatttaaca ggaatattaa taatattaaa
    17941 caatattaag gcgataaaga tacctaaagc accgccgtct ttagaataag acgcaccaat
    18001 actaaaacag ataggaacta gtgtcagcca gaacaaacta tctcctagac cagccagtgg
    18061 ccccatcaag ccaactttaa taccagtaat tgaagctgca ccttcatttc cttcttgttc
    18121 ttccatagcg gaagtaactc caagaataaa tggtgccgct gtttgatgag tattgaaaaa
    18181 ctcaaggtga cgtttcattg caggagaagc tgaatctttg tctgggtata gttttttcaa
    18241 tactggaaga attgtatata gaaaacctag gttctgcatt ctctcatagt tccatgaaga
    18301 accatacata aaacttcgtt tgaaaacttt tttaagttca actttagtta ctttattatt
    18361 catcatagat caagatcctc ctcaacatca ctacttgaag ttgtttcttg tggtttactt
    18421 ccaatcatat cgtagaagta tgctaccgca ataccaacta gtgagatccc aatggttgac
    18481 attcctccat acacagaaca aatgaatcca atcaacaaga atacccacat atttttcttg
    18541 agcatcatat ttaaaagcat accaaaacca attgaaggta gtaaagcacc tgcagagtta
    18601 agtccctgca taacgattgg tggaacctta gcaaacaagt ctgccacata ttcccctcca
    18661 agcataatag ctaggaaaat tggtacaatt ttaaataacg tgattaaaac caaacttgaa
    18721 taatgataaa aaccgatctt tgaataatct ccgtttttag catcattatc agcttttttc
    18781 acaaaataaa catctaaagt ttttgcaaga acatccaact gttgggtagc aactgcaatt
    18841 ggaactgcta tagcgatacc agcagtttct ccttgaccag ataaaatacc aaatgcagta
    18901 ccaataatcg cacctgaaat agtatctggt ggagtgtaac ctccaatacc tgttacaccg
    18961 agccaagtta attcaagagc tgaaccaata agaacacctt gggtgaaatc tcctaagact
    19021 aagccaacca ttgcacttgt aactaacgga cggtgaatca taaataacgg tccattatag
    19081 tcaatagtgg caataatccc aactaatgtc accagtaatg cttgtgtgaa tagcatatac
    19141 tgtacctcct taaattattt ttataaaaat ttttccaaca ttgtaacttt atcattagga
    19201 accatttgaa tttcaactct cgttccctta tcaactattt tcttaaaata atatttgtct
    19261 tcttcaccta gagctacacc tcccgttacc ttttcatttt cctccgtttt actcatctgt
    19321 cctacattga ggtactccaa ttttaaattt ccttcaatag aatcatacac atcttttgga
    19381 tttgtatata tcagcattgt tctctttttt attggcacag agtttaaaac ttccacaaac
    19441 cgttttacac taaagaaaac aatttttaaa cctactggtg cagaaatctt taaaatagat
    19501 tgtcgtgttt tatcttctga gatgcgatca ttaacaatga taacttgctc aatatcatac
    19561 ttttttagcc acgtagtgac aacttgacca tgtaccagac ggtcatcaat acgaacaaac
    19621 tctatagaca taaatcttct tcctcctcta cgttaagttg ttgtttaaca ttaaacaaac
    19681 tattttgagc attgtgaaca atttcttcta aattgatttt tgaatcataa tttgatatta
    19741 attccactag gagagggata ttaaaccctg ttacaatatc aactgaatcc aaatttaaaa
    19801 accgtgacaa agcaacatta ttaggacttc ctccaatcaa gtcagtcaaa acgataacct
    19861 cttgatttga gtctaacagt tcatttactt gatttttaaa ataatgttca aactctacaa
    19921 tattctctcc aggcatcaaa cctaatgtcc taactctatc atttgttgtc tcaccaacaa
    19981 acatttctgc ggtcatgaga gctccgctag caaaattacc atgactggca actaaaattc
    20041 ctctattaaa cattttctct ttcaacaact actcctttct taaggataat attagcataa
    20101 agtgaagttt ctcctgtagc aacaatagca taagctttct tactacgttc ataaaagtct
    20161 tctcttctaa gataagtaat cgttttaaga tctgtaccat gaccttcaat catctgtcta
    20221 taggtacccc atatcttagg aatatcatca cccgaaacaa cgttcataaa ctgaattgaa
    20281 ctatcgacgt aactatctaa tggcattaaa tacagaatgg aatctaataa ttctggaata
    20341 tttacaccat cacaacgaat tagcttattt gcacatgagg cagaaggata attcgcgtca
    20401 gctaatacta tttcatctcc atgtcccatt tccattaaag tcttcaataa atctggagaa
    20461 atatttttcg gtatatgttt taacattaat atcctcccta ttttctctga ccgtatgttt
    20521 taaatttttc tgccattaaa tccatctcct catcaggaag aactactggc tctccaaaat
    20581 tcttagctaa acaataaatt tttgcacaat attcaacttc ttcaacaata ttaaatgcat
    20641 tcaataaatt ttgtgcacct gctaaaattc catgattcgc tagtaaaact gctctacgac
    20701 cttccattgc tttagctgca ttcacagcca attctttcgt accatatgtt gcatactcag
    20761 ctacccgaac atctttccct gccactgcaa tcatataatg actagccgga agtggttctc
    20821 tgagacaagc taatactgtt gcataagttg tatgagcatg gataattgca tcgatatcat
    20881 cacgagtttg atattgaatc aaatgcatat accattcgct agatggcaag cgttctccct
    20941 ctacaacatt tccattaata tccatcacta caatatcgga ttctttgatt tcaaagaaat
    21001 caatacccga cggggtaatt gccatcaatt gtttttcacg atcgaaaaca ctgagattcc
    21061 cacctgttcc tttcgtcaaa tctgtttcta ctagcttctt gccatactta attaattctt
    21121 gttttacatc tgacattctt gtcctcctca tatcaaaaca ctaaatattt ttcaattcac
    21181 caattatccc cccttcttgt acaaaactta agaaggggga gggaggcaaa tttacaaact
    21241 ctcaatcttt ttaattcttt tgggagtaat aactctctaa ttgtagaaac tcctcaataa
    21301 catggtgagc ttcttccatc ccttttaatt gtcccatagc tatgagctgc acaacaatat
    21361 tccccacagc tgtaccctca gtcgaacctg taagaacctc tttaccagtt ctatcagcaa
    21421 tcatttggtt aaaataactg gctctagcac ctcctccaat cacatatatc ctcttataaa
    21481 ccttatgagt tagttcttct agtaactcta tcgctttcct atacgtttca gctaggcttt
    21541 cataaacaat cttaaatagt tgtccatctg tccactctct agtttcatga tgataagcta
    21601 gatattctgt caaagtcttg tgcatatcag attctgttgc aaattcagtt gattcagtat
    21661 caatcagagg aagattttct ttttctttct ccaccattgt cctaatatca tcaaaagaat
    21721 aggctttccc tcttcgttca aatgaacgtc ttagttcctc tatgatccac aaccctgtac
    21781 aattcttcag aaatgtaatc actccatctt taccgacttc atttgtaaat ccataactga
    21841 aggattcggt agtaagaatc ggtgaagtaa gttccactcc aaccaaagac caagtacctg
    21901 atgaaataaa taaactacct tctgtcttag gtactgagac aatcgcgctt gctgtatcat
    21961 gactacaaac attcacaaca ggaatatcgc ctaaaccata ctcctttttt atccttccaa
    22021 gaacatttcc ctctgaaaca atttcaggaa gtaaagatga attcaattca aatagtttta
    22081 agatattctg attccaattt tgactcctag gatcaaataa ttgagttgtt gaagcaatgc
    22141 ttttttctgt agcaaactta cctgtcaaga gataattaaa caaatctggc attaaaagaa
    22201 tcttattggt cttatagaaa gagtcaggag attcttgacg tgccttaaag agttgaaaca
    22261 aggtatttat ctccataatc tgatttcctg tctctgaata cagtttttct aattcagtca
    22321 tttcagatat ttcctttaac actccctttg ttctttcatc acgataatga acaggttgtg
    22381 ataacagctt accttcatta tcaatcaggc caaaatcaac tccccatgtg tcaataccga
    22441 tagataaaat cttgtaacta gtattagcca agcggatact ttcaagaatt ttagctagta
    22501 gaaagtcaac atcccaagat aaatgccctt ttactctaat aggtagatta gaaaagcgat
    22561 ttatttcttc cattactagt ttattttcag aaaggtaacc aacgattgct cttccagaag
    22621 tcgcacctaa atctattgct aaaaccgctt ccatttttct tctctcttcg tccttgatta
    22681 agtttattat aatccccaca ttttattttt tcaatatgtg aacgcttact tggataatgt
    22741 tcaaatgtta acccaatatt cataaaaata attcaaattc ctccaatttg tgctataata
    22801 tagttgaaat gataaattag gaggagctta tgataaaaga tgaacgtgta cttgaattga
    22861 ttgaaattat caaaaagaaa aaaagaattg ccgtaaaaga gctggcagaa atcactttct
    22921 ccagcacaag taccttacgt cgtgatttaa ttttcttaga aaatcaaggt cttatcaaaa
    22981 gaaagcacgg atacgtgacc ctgtcctcta tgaacacaat tgaactttct catcaaatac
    23041 gtgaaggaga aagtactagg caaaaaagac taatcgctag tctcgctaaa gactttattc
    23101 ggtctggtat gtgtatctat ctggattcca gtactactgt ctacgaactc tgtccctatc
    23161 tttctgaact tgataatttg attattttta caaatggttt acatactgca caaaccctat
    23221 ctgaaactgt taaagatagc tccaaaatct ttatcacatc tggcgaggtc aaacatcaat
    23281 cctgttccgt ggtcaactat gataaggaaa attctttatt agatcatttt aatatcgatt
    23341 tagcattttg ttcagcaaga ggtattgatg accaatatgt ttatgaagct tctctcagcc
    23401 aagctatttc aaaaaagaat attattgaca aagcccatga aaccatctta ctgattgata
    23461 gttctaaatt ttacaagact ggatttttta aaattaatcc cctctccaaa tacacaacct
    23521 ttatttcaga caccgtgcca gatcaaaaat tattagacgc agtcgaatta tttgatggag
    23581 aatgggtttc tgatattcaa tgaaaatcaa ataggaagct agtctcagct tgctcaaagt
    23641 acagatttga aaactgatga agtcagctcg aaacactgtt ttgaggttgt agatagaact
    23701 gatgaagtca gtcacatata tacggaaaga cgaagctgac atgatgtgaa gagattttcg
    23761 aagagtattc gttctgtctg ctgactgatt tacaaatatt caccacatga cattattttc
    23821 ttagcaaccc caaaaacaga ggctggacaa aaactcaatt tcaggagaaa atggagtaaa
    23881 ccttcccaca ataaaacgca tagtatcaag tttttgcaca cctgatatta tgcgtttttc
    23941 tgattttaaa gactttgtcg cctagaccct atatttcaag aattaagtga ccttgatgat
    24001 ctaaatttat tgtggtatac tatttttgtc atcggttacc gattacgttc ctatgggttc
    24061 gtgagaggag gtgaaactaa tgagccttat catagagctc gctcttacta ttatagcgga
    24121 tgttatagct ggaattatct tgtatttcgt ctgcagatgg ctagatagta aggagtagac
    24181 cgactgacta gcctataaac acccgttaaa tcgctaagat acgtcaaaaa agcccttaac
    24241 tacggccata gttaggggct ttggtgttct aatgaacctt atcaattaac tacattttag
    24301 catataatct acaatagttc aagcattaag tgaggttgat gatctaaatt tagtgtggta
    24361 tactattttt gtcatcggtt accgattacg ttcctatggg ttcgtgagag gaggtgaaac
    24421 taatgagcct tataccagag cttgctctta ctattatagc agatgttata gctggaatta
    24481 tcttgtattt cgtctgcaaa tggctagatg gtaagaagta gaccgactga ctagcctata
    24541 aacacccatt aaatcgctaa gatacgtcaa aaaagccctt aactatggca ctagttaggg
    24601 gctttggtgt tctaatgaac cttatacact aactacattc tagcatataa gcccagatat
    24661 ttcaagagtt ttatttattt tttcaggttc ccttagttct gaaaggtcta taatgaagtt
    24721 agccatctag tatcaaaaaa ccgactagct cttatgaact agtcgatttc tcatcaatgc
    24781 gccaacattt cttgggcgat ttcttggcca gataggttat ctgggtagta ggttggccag
    24841 ttgtccattt cttcaaagag ggcttcttgg cttgtgcctc caaagaagat atggaaatgt
    24901 tctgccttaa ctggggcaac attgtggtca ctaaactgaa catacttgaa ttgtccagcg
    24961 tcagcatctg tggcttcaaa gaggaaacgc acgccacgat tgcctttctt gtaagtcaaa
    25021 attttcttac cgacatactt gtaagtgtat ttcttgcttt gtccaccttg aacaaattcc
    25081 atagtattat cagtaatgtt aatcttagtc acatctgtct gatagccttt tgtatagtaa
    25141 gccttgtact cagcctgggt catcttacca gttaacttag ccttgtagtc aaagacttgg
    25201 tcaaacgtgc cgtcttcaag gaaaggataa actgattgcc agttacctgc atagtcactc
    25261 aaggtacggt ccttgacagc tgcatcctcg aagtaaccat tttggactgt cttggtatcc
    25321 tctgcctttt caggttcgat tgctgggcct tcttggtctg ttgtttgttt caaagccttg
    25381 aggtttttct ccatcacgga aatgtagttt tctccagcct tggtgtcctc ttctgtcaga
    25441 ctttctaaag gattgaggac atcagttttg acacctgctt cttttgaaag tgtgttagca
    25501 agggcttgtg aggcattttc ttcaaaatag atataggcga ttttattttt cttgacatac
    25561 tctgtcaatt ctgccaagcg agcagctgat ggctctgcat ctggagaaag tcctgagatt
    25621 gcgacttgtt tgagtccata gtccaaggca agatagttaa aggctgcgtg ttgagtcaca
    25681 aagctctttt gttttgcttg agacaagcct tctgcgtaag ccttatccaa ggcttgcaat
    25741 ttttcgatat aggcagctgc attcttctca aaggtctctt ttttatcagg ataatctgct
    25801 gacaagctgt cgcggatgtg ctctactagt ttaatggcac gaactggtga taaccaaaca
    25861 tgggggtcaa actcatggtg atgaccttct tctccatggt catgatctcc ctcttcttcc
    25921 tcgccacctg gcaagagcaa catatcgcct gtcgccttga tggttttcac ttttttctta
    25981 tccaaggtat ctagcaattt aggtacccat gtttccatgt tttcattttc ataaacaaag
    26041 gtatctgcat cttggatttt ggcaactgcc ttggcagatg gttcgtattc atgaggttct
    26101 gtcccagcac cgattaggag ttctacatta gccgtatctc ctgcgacttg cttggtaaat
    26161 tcatagacag ggtaaaaggt tgtcacgata ttgagtttac catctgcctg tttttgattg
    26221 gaacaagcca ctaaaaacaa ggcacataga ctggctagta ataagctaat ttttttcacg
    26281 ttcgtctcct atttgataaa acgtcttact aaactgatta gtataaagac agttacaaaa
    26341 ataatggtaa tacttgcact tgcaggtgtt tctgcatagt aggaaatgta aagtcctgct
    26401 accattccca aaaagccaat cgcactggca agcagcataa ccgatttaaa gtttttcccc
    26461 agacgcaggg caatactagc tggcaagacc ataatggtcg ataccagaag agctcctgct
    26521 gcaggaatca taagggcaat agccacccct gtcaccatgt taaaaagaat ggacatggta
    26581 cgaactggca agccatccac aaaggccgta tcttcgtcaa aagttaagat atacatagga
    26641 cgaagaaaga gaaaggtcaa aatcaaaaca accgccgcaa tgacaaagag ggaaatgacc
    26701 tgttcttcac tgatagtcac gatcgaacca aagagatatt ggtccaaact cattgaactc
    26761 gagcttttac ccttgctcat gacaatcaga gaaacagcca gacctgttga catgaggata
    26821 gctgtcccga tttccataaa gctcttgtaa accgtacgga gatactccag aaagaccgcc
    26881 gcaatcaaga caatggcaat agtagaaaca gttggagaaa tccccaaaac cagaccaaag
    26941 gctacacctg aaagtgagac gtggctaagg gtatcactca tcaaactctg acgacgcaag
    27001 atgaggaagg ttcccaatac cggtgagaaa agactcatag caataaccgc caaaaaggcg
    27061 cgttgtataa agtcgtaaga taataaacta agcatggccc acctcctggc cattctcatg
    27121 aacgttgaaa caacgccatg gcgagtcttg gttacggact agatgaatat tgcgatccgc
    27181 ataatcctta acttcttcag ggtcatgggt aatcatcaaa acagccttgc catgatgatg
    27241 ggcgctgtgg tgcatgagtt cgtaaaattc atttttactt cctgcatcca tccccgttgt
    27301 cggctcgtct aggataaaca catcagggtc agaagcaaac atacgcgcaa ttaccgctcg
    27361 ctgcttttgt cccccagata gagaccccaa gcgtttgtct cgatgttccc acatgccaac
    27421 tgagtccaga ctggccttga tatgctcctc atcatgagca ttcaaacgac ggaaccagcc
    27481 ttttctcgga tagcgacccg acttgacaaa ttcatagacc gtacttggaa aaccagcatt
    27541 aaaactggca atttgttgag gaagataggc tattctcaat ttcttacctt gcgtatttgt
    27601 ctttgaaata gccacctttc caatgcgtgg ttgcagaatt ccaagactag ccttgatgag
    27661 cgtcgtctta gccgctccat tttccccagt caaggtaaca aattccccac tatcaacaca
    27721 ataattgata tgttcaagaa caggctcctt atcataatag aaggacaaat cctctaccgt
    27781 aatatatctc attatttgat ttctcctact aaagcagtca aaaaccgctg aatcactttt
    27841 tgttcatttg gagtaaactg agtcgccact tgttcatagg ttaaaagtgt atgctcatgg
    27901 tgatggtggt gctcctcagc gattggacga gccaagtcag tcaactgata aaaaatcaca
    27961 cgcgcatctt tagaatcttt agatgtttcc aacatccctt ccttgaccaa agacttaatg
    28021 gccttggtaa ctgccgcctg actgacattg agacgacggg ccaattctga atttgttaaa
    28081 gattcctctg acaagagcat aaggatatgc tcctgagtat tggtcagggc cacctcgcta
    28141 gtgcaatgac ctattaggat ttcatgctga ttttccgcct gcaaaatcac ctcattcaaa
    28201 aaagcattga tatcctttgc tagctgtctc atatctgact cctttccttt tagacttctc
    28261 ttttttaaga gaaaaatact attctttgac attttgttta ccagttaatt atatcacaag
    28321 caaaaaaaga gtcaagaaaa aacgtgaaaa ctagtttcat tcttgaactc ttctatatta
    28381 tattatctat tgaaattctt tgacatctcc atcataagtc gcccaatctt tgctgaaaaa
    28441 gcgctcattc agatggtaag tcggagctgg tgtgggattg gataggaaag gatcaactgc
    28501 cttgtcaaaa gccaaccaac ccaaccaacc aaggtgaatg gtgtccttca taaagaaagg
    28561 ctccccgccg tccttagaaa aatctgctat attggtaaaa ccttgacttt ctaactggta
    28621 gcgaatcttc tgcaccgttt gttggtacat atcctctcgt agaccagcat agtccatcca
    28681 ttttttatta acaggtggaa tgataaaaat cgggtttacc ttagatttag aaaactgtgt
    28741 taaaaccaac tgcaagtcat tatactctgg cgacttgaga taggtaaagc ttttctgaga
    28801 atcctttaat ttcttcaaat ccttcttgat ctgctcatta tagaaataat tttccattcc
    28861 catctcatta ttggaagtat ttttttcagc atctgctttg acaacatctt ctattgcttg
    28921 ataagaaaac tggtctggca agatttttaa atacttagct acatgcttat cgtagttaac
    28981 atagcctcta accgaaaact gaccaaaaaa ggaggcttgg cgttcattaa aacgagccaa
    29041 taattcaatc atttcattgt ctgctgtcga caattctcct ttacttgcca acttctgaac
    29101 caggtccttc atagctacgt ttgggaactg ttgcagtaag cgagtcgctg catattgact
    29161 agcctgatcc ccagattgat gtttcagaaa actagtcaac tggtctccat taaaatactg
    29221 ctggaaggct gctggatcat agccattttt actgaaccac tgaggtgaga taacatacac
    29281 aacttgttta ttctccagct gtggtaacat ctgttgcatt ccaaaatatt ggttaagcga
    29341 tgcagctccc ccctgtccta aaagataagg acggtaggaa cgattgtatt tctcagctaa
    29401 taccgcagga tgagcaccgt caaaacgaag ccattcacta gagccaaaga agggaacaaa
    29461 acgcacattt ggatcagata gtgctctgac tttttgactt cgctccttaa aactatcgat
    29521 agtagtagcc actgctgaac gcttttcagc tcctagatta tgatgcatct cagtaggata
    29581 aaagaaaatg agcagaaaaa ccaacaaacc agcgatcaag accggtccga agatcatcca
    29641 taagcgttta agcattttgt agctccacaa taccagctat gattttatta gctgtattcc
    29701 agtcgtcacg accaaactct gttacaggga cacgaatgtc aaaacggttc tcaatctcca
    29761 caatcaactc aaccgttccc atactatcca agacacctgc atcaaaaaga tcttcatcca
    29821 tcatgtcaga aacatcttcc ataaacaact catcaataat ttcaataact tctgatttga
    29881 tatccatatt ttatttcctt ttatttttta aaccatagat tattcaagaa tccagaaaag
    29941 attaagaatg acaacatgac aacatggaaa gtgacaacca tgccaagcaa ctgaatccag
    30001 cgattctcag gtagggcagc cttccctgct tttttccgtt ccttattgag cgtttttttc
    30061 ttgcgaaccc aggcatcatt gatgaccaag cctagtccat gaaagagtcc ataggcgata
    30121 tagtaccagg tcacaccatg ccaaaatccc ataatcagca tatttacaat gtaagccatg
    30181 cttgaggtta cattacgatt tttaaagact ttctttctgg ttaacaccat caccattcgc
    30241 ataaagacaa agtcacggaa ccagaaggac agactcatat gccagcgatt ccaaaactcc
    30301 tttaaatccc ttgataaaaa gggcttgtta aagttgatag ggctacggat tcccatcaag
    30361 tttgagatgg ccaaagcaaa catagaataa cctgcaaagt caaagaagag ctccagacca
    30421 aaagtataca taactgccaa ggcatagaga ttaaagaagc cacctgactg caaggctaaa
    30481 ttcttcagag gaggtagtaa ggtctctcct aaaacatgag ctaggataaa cttatacaaa
    30541 aagccccaca tgatatagcg gacagattca tccagcatat ccatcaactc atctcgctca
    30601 ggaatggtct gataattttc attaaatcgc ttaaagcgat cgattggacc actcgagaaa
    30661 gttggcatga agagaaggaa acggaggaat tcccagaggg taaaatcctt aatcactcca
    30721 tctctcagct cgatgataat cccaaccgaa cgaaaggtca ggtaagaaat tcccaagaac
    30781 ccaagcaaag actgcgttcc attgatagct ggttgcacct tgacaaagat aatcggaagt
    30841 agggacagaa aactaactaa gtagaagacc cacttgccat ccttgctttt tcgataatgc
    30901 ttgtagaaaa gcaggagcaa tatttcccag caaaggtaaa tacccaaggc agctagttga
    30961 ttggtctttc cacccaccaa catggtgaca ataaagaaga gacttaccaa cacttcatac
    31021 caggcaaagc gtttcttgaa aaagaggcct ataaagatgg gcaaggttgc agcaatcaca
    31081 taaacaaaat actgaggatt gccatatggc tctaaatgag gaagctgttg aaaaaactcc
    31141 atcatctctt attcacctcg ttaatcaatc ctttgatgtc aatctttcca tttggagtta
    31201 gtggcaaact gtctcggtaa aggaatttag atggcatcat gtaggacatc atgatgtctg
    31261 tcaggtcttc cttgatggcc ttggtaatat cgatatctcg ctcaaactgc tcacgaacac
    31321 cgtcttttaa gatgacataa gccaatagat tttgtacctt atggtccttg ttatagcgcg
    31381 gtactgcgac agcagattcg ataaagcgag acttgttgag gttttgagag acatcttcta
    31441 actcaatgcg gtaaccgtta aacttaatct ggaagtccat gcgtccgccg taaagaagca
    31501 agccctcatc tgtcatggtt cccacatcgc ctgtgtgata ggctggcaga ccttcaaact
    31561 caaagaaggc ttctgctgtt ttttcaggat tgttcatata accttttgaa acagctggcc
    31621 cagaaacaat gatttctccc tgttcgccat ttggcagttt atttccttcc tcgtcaatga
    31681 taaaggttgg agaatcagcc ttggtatagc cgattggtag gcgtttgaga gtcgctaaca
    31741 tctcgtctgt cacggcaact gctgacagag ctactgtcgc ttctgttggg ccgtaagcat
    31801 tgatgatacg ggcatttggg aaacgctcgc gcagtttttg agctgttttg accgtcaatt
    31861 cttcaccatc aaagtagaaa tgcgtgattc caggcatttt ctcactgttg aagtattcag
    31921 acaacatggc catatctgca aaggatggtg ttgatgtcca gatagcgatt ggcaatgaaa
    31981 agatagccgc aaagagttgc ttaaagtcct gagtgatgac tgaaggaaga gtgaaaagcg
    32041 taccaccaag tgccaaggtc ggtgcccaat acatgacaga caagtcaaaa gaataaggtg
    32101 gctgtgccag catttgcgga cgactcggtg tcgcaaattc cttatccgta atcatccagt
    32161 ttgtaaagct gaggagatta tcatgtgaaa tctgcactcc cttaggctta ccagtcgtac
    32221 cagaagtaaa gataatgtag taattatcat ctcccttgac tggatgcgtg atttcatagt
    32281 tgttcccttg ggcaaaggct tcttgaacct gagctagatt tatcattggt gtagaaacct
    32341 gctccaaggg aaaggctgaa atggcaataa tcaagcttgg ctctgctact tctaaaatag
    32401 ctgaaactcg ctccaaggcc gaatggctat caattggaat gtaggcatga cctgacttag
    32461 tcagcgctac aaaggttgcc aacatttcat attcttggcc accaaaaaca accacaggag
    32521 acttctcagg caagcctagt tggtcaatga ctgcagccaa actatccgaa tcagccttta
    32581 aatcgccata agtgtgttcc tgccccaaaa cattatagac aggatagcta ggctgtgtct
    32641 gagcaaaatg ctcaatggtt tcaatcatat ctgctattgg tttatttgac acaataggga
    32701 ttctccttca agttaaaatt cattatagat aaagcttcct tgaccctgac caagatagct
    32761 aaagaagtaa agcagcccta gaaagataag aaaatacaag gctgtccgac caagaaagag
    32821 gtacaattct tttctctgtt tcatcaagaa aaaccattca tttctgtaat ttttcgctaa
    32881 aataagagtg attcttacta gcttattttt ctaccattgt accactttat atagtatctt
    32941 ttcaattgtt taccgtatgt ttccaataga tttcagctta ttttaaggat tatacagttt
    33001 ttctatgtat attttcaaat agagtgatcc tgcttcaaaa ctccatttca ggagacaatg
    33061 aagtaaatct tcccataata aaacacacaa tatcaagttt tttcaacacc tgatactatg
    33121 cgcttttctg atttttaaag actttttaac cactctctca tttaaaataa tctcgtctga
    33181 tataaattaa aatagcttct atcatcagac aaatggctga tagccaaaaa ctgatgctaa
    33241 taccaaaact ctcagtaata tagctcatta gcaaaacaaa tactgaaaat gctaatgtag
    33301 aaatcacttc aagaacggaa tagacattaa ctaaatgatt ttcctctact gtttcctgaa
    33361 gaaatacact ttcaggaact tcttttagtt gcgataacat accaactaaa gctgaaaata
    33421 ataaaaacat ctgtgcgttt ggaaaatata gaatagtcag tgtcactatt gccatagcta
    33481 caagaggaaa aagaatactt tcccatttag cagcaaggaa cttttcagat agcctaaaag
    33541 caattaagcc actaattata ataccaatag agtatgctgt attagaatat ccccagtaac
    33601 tttccgtttt atttaataac tccgttacaa aaacaagtat aatggaagaa acccaaatcg
    33661 tatttgaaaa aatttccaat aaatttgctg atacaaaaag tcttaatcta ggatttctag
    33721 caactaactt ccaacctttg agcaaaattt caagattagt ttctgactct aacacctcca
    33781 cttcagcgtt aggaagaaat aacatcagaa agctagaaat gatatacaag actaaattga
    33841 tacacgtggt aggtaacaga ccaattgttg caaacaagag tccacctaat ccccaaccta
    33901 tcaattgaac agcttcacca gtcattgata aggctgaatt agccttaccc aaatcggtcg
    33961 catagcgtgg cacaatagca taggaaacgg gtgctgcaaa accatctagt atggaaattg
    34021 caacaacaaa tagataggtc accaaaggcg ctacggattg cattacggta aacattccta
    34081 ccagtatcgc caataatata gtctttccaa attgagataa agataaaacc ctatttagcg
    34141 ctaacctttt agtaaccaac ggaactaaaa gactcgcaac aaaagaggat attcctatta
    34201 agataggaac tagtgatgtg gcaattactg attttgaaat aatgtatatg ttagcaatga
    34261 ttgttactct aaagaaaata tctgctaaat ttgcaaataa ttgagagact aacaacttga
    34321 caaatgaatt agacatgtag cgctccccct ttagttacaa actttggaat taaatttgat
    34381 ttttaatatt ttagcataaa atagcagaaa acaaaagtga ggttttttac atgaaaaaac
    34441 aaaaactatt gcctttatta ttcctaattt taggaggaat tatgattatc gttgttggct
    34501 agtactaaga agttagttag tagaataatt acatcttcaa tcgaaaaaga gactggaaaa
    34561 agtcttaaaa atcagaaaaa cgctcaaatc ctttggcgct ctaagctttt ctaatgatag
    34621 atttagatag tcaaaaaaat atctgaaaag ttcccaggat cgtcgtctca gcatcaaaaa
    34681 tacgtgaaat ttgcataatt aaaataaatt tcaggggagt taatcgagta ggggataatc
    34741 tctagcccct ctcacaccac cgtacgtgcc gttcggcata cagcggttca actaactttt
    34801 aacgcatgtc gttcaaggta ataatccaaa cacgaaacca gtccacgttt ttccaggact
    34861 ggttttgata tagcacgttt aagtaccgac ttctgagcta ctaattgata atggtcgccc
    34921 cagccagata ccttatctgc tatccattta ggaactccta acttaagcaa tccccataat
    34981 cgtctcgatt tcttcttcca ttgcttccag ataatcactc gtaggcgagt acgcaagcgc
    35041 tcatctatgc tggcgactat acttttcata tttcccaatg agaaatagtt tatccatcct
    35101 cgaatagaca aattcagttg ctcaatacgt cttgttaggt ctatactcca tttcctctgt
    35161 gttagtttct tcaatttaag cttaaatctc cgaacactat cttgatgtgg acgacttttc
    35221 caaccatctg atgatttcca gaacccaaaa cctagatatt tcaactctct tggtctggta
    35281 atcttagtct tggtcatgtt tactttcaaa cctagccgtt tctcaataaa acgactgact
    35341 gaatacatca cacgcttagc ggctgcctcg cttccgaccg tatcacacaa tcatctgcgt
    35401 agcgcacaaa tcgaagtccc ctcttttcta attccttgtc caattcatta agcatgatat
    35461 tggataagag aggagataaa tttcctccct gtggtgtacc aactagtgtt ttataacgtt
    35521 gaccattaat gataacacct gaatgaagat acttacgaat caaggattcc gtatctccgt
    35581 cttcgataat gttatgtact aaggacatca atctatcttg aggaactgta tcgaaaaatt
    35641 tctctaggtc tatatccact atccactcat agccgtcatt taagtattct aagagcttca
    35701 tgatggcttt ttcacatgac ctatttggtc tgaaaccata actcgtatct gagaaatggg
    35761 gttcacaaat ggggctcatg acttggacaa tggcctgttg aatcattcta tccataactg
    35821 ttgaaattcc tagttgacgg atgcctccgt ctggtttagg tatctcaact ttaagaactg
    35881 gttgaggctt atattttctc tgttttatca gttccttagt caagcgccag ttttgtctga
    35941 gataattatc catctcttcg atagtcattc catcaatccc agctgagcct ttattggatt
    36001 ttacttgatt gtaggcttcc agcatatttt cgcgtgataa tatcttatct agcagttttg
    36061 acatgtgcgt attcctttct tgttttggtg cctgagggac atcttatatt ggtgaacctt
    36121 catctagtca ttacgtgtca aagtccagtt ctatcagacc actcatttta cagacacaag
    36181 tgaagtagga ttacttcgat ctgtcgtttt ctctttctag cgacagacct caaacagtct
    36241 ctccccagac tgtttgagta ttcacccctt cgctccactt ccactacaga agtttcctca
    36301 ctactatggg ctcggctgac ttctcatgat tcgttgttac tacgctttca gcgctcatga
    36361 aacctcacgg gataagtcgt acatctttcc tcgtttatac aagatatgag gacgttaaaa
    36421 ggttacagtg aaaataggaa atctgacgca gagtctttag actctagaaa gatttatctt
    36481 tttcacacaa accttagtcc gaattcaatt actctcgtga tttacacata taggttacga
    36541 ctaccttttt ggactttaga gtttgaagcc tccttatccg ctatatacgc cttactatca
    36601 cgttcctgtt cgtagagcca cgatttcgct atcccttcct ctgacgattc ttatttcctg
    36661 cgtcagactt aaaacggtct atccccagac cgttttaatc cgctacctca cgatagtcag
    36721 gcttgggaat cgctattggg ttcacc
//
LOCUS       DAVKUR010000014        36229 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKUR010000014 DAVKUR010000000
VERSION     DAVKUR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.014"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            66..539
                     /locus_tag="VW749_000833"
     CDS             66..539
                     /locus_tag="VW749_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0174895.1"
                     /translation="MKKYTEVFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGN
                     TEKYIATYINQEFKSYIDHMLNKEAKIIGFSAGPLLLGEKVYVSPNDNSDHQIKIKNG
                     LGLFSQFLISVHYDSWNDKANKDRAEELDNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            821..1069
                     /locus_tag="VW749_000834"
     CDS             821..1069
                     /locus_tag="VW749_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV0174896.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILTYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            1245..1498
                     /locus_tag="VW749_000835"
                     /pseudo
     CDS             1245..1498
                     /locus_tag="VW749_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1626..2855
                     /locus_tag="VW749_000836"
     CDS             1626..2855
                     /locus_tag="VW749_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0174897.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLMMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2875..5571
                     /gene="ppc"
                     /locus_tag="VW749_000837"
     CDS             2875..5571
                     /gene="ppc"
                     /locus_tag="VW749_000837"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0174898.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5654..5871
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5984..6988
                     /locus_tag="VW749_000838"
     CDS             5984..6988
                     /locus_tag="VW749_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0174899.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            7057..7923
                     /locus_tag="VW749_000839"
     CDS             7057..7923
                     /locus_tag="VW749_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174900.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7920..8678
                     /locus_tag="VW749_000840"
     CDS             7920..8678
                     /locus_tag="VW749_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0174901.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            8768..10528
                     /gene="dnaG"
                     /locus_tag="VW749_000841"
     CDS             8768..10528
                     /gene="dnaG"
                     /locus_tag="VW749_000841"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0174902.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10531..11640
                     /gene="rpoD"
                     /locus_tag="VW749_000842"
     CDS             10531..11640
                     /gene="rpoD"
                     /locus_tag="VW749_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0174903.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11654..11983
                     /locus_tag="VW749_000843"
     CDS             11654..11983
                     /locus_tag="VW749_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0174904.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12098..13141
                     /gene="cpoA"
                     /locus_tag="VW749_000844"
     CDS             12098..13141
                     /gene="cpoA"
                     /locus_tag="VW749_000844"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0174905.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13157..14482
                     /locus_tag="VW749_000845"
     CDS             13157..14482
                     /locus_tag="VW749_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0174906.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14513..14689
                     /locus_tag="VW749_000846"
     CDS             14513..14689
                     /locus_tag="VW749_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0174907.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIVPVATDY"
     gene            14748..14882
                     /locus_tag="VW749_000847"
     CDS             14748..14882
                     /locus_tag="VW749_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0174908.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14946..16256
                     /gene="obgE"
                     /locus_tag="VW749_000848"
     CDS             14946..16256
                     /gene="obgE"
                     /locus_tag="VW749_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0174909.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16266..16424
                     /locus_tag="VW749_000849"
     CDS             16266..16424
                     /locus_tag="VW749_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174910.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(16476..17802)
                     /locus_tag="VW749_000850"
                     /pseudo
     CDS             complement(16476..17802)
                     /locus_tag="VW749_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            18905..20164
                     /locus_tag="VW749_000851"
     CDS             18905..20164
                     /locus_tag="VW749_000851"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0174911.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            20180..20731
                     /locus_tag="VW749_000852"
     CDS             20180..20731
                     /locus_tag="VW749_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0174912.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            20724..22001
                     /locus_tag="VW749_000853"
     CDS             20724..22001
                     /locus_tag="VW749_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0174913.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            22017..22877
                     /locus_tag="VW749_000854"
     CDS             22017..22877
                     /locus_tag="VW749_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0174914.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            23100..23210
                     /locus_tag="VW749_000855"
                     /pseudo
     CDS             23100..23210
                     /locus_tag="VW749_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            23256..24060
                     /locus_tag="VW749_000856"
     CDS             join(23256..23624,23626..24060)
                     /locus_tag="VW749_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0174915.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            24252..26543
                     /gene="pcrA"
                     /locus_tag="VW749_000857"
     CDS             24252..26543
                     /gene="pcrA"
                     /locus_tag="VW749_000857"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0174916.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            26586..27266
                     /gene="radC"
                     /locus_tag="VW749_000858"
     CDS             26586..27266
                     /gene="radC"
                     /locus_tag="VW749_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0174917.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(27263..27952)
                     /locus_tag="VW749_000859"
     CDS             complement(27263..27952)
                     /locus_tag="VW749_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0174918.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDSGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(27970..28611)
                     /locus_tag="VW749_000860"
     CDS             complement(27970..28611)
                     /locus_tag="VW749_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0174919.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(28694..28909)
                     /locus_tag="VW749_000861"
     CDS             complement(28694..28909)
                     /locus_tag="VW749_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0174920.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(28917..29264)
                     /locus_tag="VW749_000862"
     CDS             complement(28917..29264)
                     /locus_tag="VW749_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0174921.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(29269..30384)
                     /locus_tag="VW749_000863"
     CDS             complement(29269..30384)
                     /locus_tag="VW749_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0174922.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(30394..31353)
                     /locus_tag="VW749_000864"
     CDS             complement(30394..31353)
                     /locus_tag="VW749_000864"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0174923.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGAPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(31466..32035)
                     /locus_tag="VW749_000865"
     CDS             complement(31466..32035)
                     /locus_tag="VW749_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0174924.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            32163..32834
                     /locus_tag="VW749_000866"
     CDS             32163..32834
                     /locus_tag="VW749_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0174925.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            32818..33636
                     /locus_tag="VW749_000867"
     CDS             32818..33636
                     /locus_tag="VW749_000867"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0174926.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            33633..34529
                     /locus_tag="VW749_000868"
     CDS             33633..34529
                     /locus_tag="VW749_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0174927.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            34573..35547
                     /gene="pta"
                     /locus_tag="VW749_000869"
     CDS             34573..35547
                     /gene="pta"
                     /locus_tag="VW749_000869"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0174928.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(35808..>36229)
                     /locus_tag="VW749_000870"
     CDS             complement(35808..>36229)
                     /locus_tag="VW749_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0174929.1"
                     /translation="SDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHF
                     QNKDPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAKLEATNNLIK
                     LIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT        10962 a         6392 c         8010 g        10865 t
ORIGIN      
        1 tattatcaac caagattaaa agaattatca tttttacagt ttttcgagaa aattgggaac
       61 cgtacatgaa aaagtacacg gaagtttttc aaagtcaatt tcctaatcta aacattgatt
      121 acttgctcct ggacactgag cagattgatc ttgatagcta tctagatgct gacataatta
      181 tcatcggtgg tggaaatacg gaaaaatata ttgctactta tattaatcag gagttcaaaa
      241 gttatatcga tcatatgctt aataaagagg caaaaattat aggattttct gcaggacccc
      301 tactattagg agaaaaagtc tatgtctcac ctaatgataa ttcagatcat cagataaaga
      361 taaaaaatgg attaggactc tttagtcagt ttttaattag tgtccattat gattcctgga
      421 atgataaagc aaataaggat agagctgaag aactcgataa tgttcccata attccactaa
      481 atgatcattc ttgtcttgta ttggataaac ttggaaacat catagagaaa attgactaac
      541 tttcataatg taaaaatgga tctaggaaat aaaagtgtag acgaactgga taggttacta
      601 gtgaaaactg caaaaagtgt tgtaaagtga atcggagtgt gcttgatgga ttttagtagt
      661 aagatagcca taaataaagg ctggtcagat gataaaaaat attgtgtgac agatcaaaat
      721 cagtaaaaat atttcttgcg tgtttctgat aagtcgaagt tagattataa aaaaatttga
      781 atttgatatg atggagaaag tagcttctct tggagttccg atgtgtaaac caattagcat
      841 tgaactctgc gatgacgaag tacattcttt acacgaatgg atagacggaa gagatgcaat
      901 agatagcatt ttaacttatt cagaaaacca acaatacaca tatggtgtag aagcaggaaa
      961 gatacttaga aagattcata caattcctgc tacagaagtt tgtgaagatt gggaaatctt
     1021 ttttaatcta aaaattgatg ataaaatctc caacgaaatg atatggtaag tccgaaacgc
     1081 tcagtgtgta agcttgttgc taaaagcgta aaaaccttgg aacgaaagga ataatagact
     1141 tcctgcgaaa caaaaataca atacaataaa actatggatg atgaagcaag taaacaatta
     1201 agcgatagcc gtttcaagag ccttgtaggt gttcagcgca cgagatgtta gctgtgttaa
     1261 aaacagctta tcaacgcaac gtaaacgcgc aaaaggtgga cgaaaaacca aattaagcct
     1321 agacgatctc ctcatggtaa ctattcaata catgcgagaa tagcgcactt atgaacaaat
     1381 tgcggctgat tttggcattc acgaaagcaa cttaatccgt cggagccaat gggttgaagt
     1441 aactcttgtt caaaatggtt ttacgatttc aaattctgcc ctaattatga aaaacagtaa
     1501 aattcgaagg attgtaaggt aagagttttt ttctttctga aaaaatggta taatagcaat
     1561 caaaactaga aaataaaacg gaatttggaa cagatttgtc tgtatcctag tagagtggtg
     1621 atgctatgaa gattagtaag aggcacttat taaattattc catcttgatt ccctacttgc
     1681 ttttatctat tttgggcttg attgtggtct attcgaccac cagtgctatt ttaattgaag
     1741 aaggcaagag cgccttgcag ttggttcgaa accaaggaat cttttggatt gttagtttga
     1801 tactgattgc cttaatttat aaattgagac tagatttttt gagaaatgag cgactaatca
     1861 ttttagttat attaatagaa atgcttttat tgttcttggc tcgttttatt ggtatttccg
     1921 taaacggggc atacggttgg atttcggttg caggaataac tattcagcca gctgagtact
     1981 taaaaatcat tattatttgg tatttagctc accgattctc caaacagcaa gaagaaatag
     2041 ctacttatga ttttcaagtt ttgactcaaa atcaatggct tccccgtgct tttaatgatt
     2101 ggcgattcgt tctcctagtt ctgattggaa gtttgggaat tttccctgat ttaggaaatg
     2161 cgactatttt agtcttggtt tccttgatga tgtatacagt tagtggaatc gcttatcgct
     2221 ggttttcaac cattctggcg ctcgtatctg ccgcttctgt ctttgtcttg accactatca
     2281 gcctaatcgg tgttgagacc ttttcaaaaa ttccagtatt tggctatgta gccaagcgct
     2341 ttagtgcctt ttttaatcct tttgccgatc gtgctgatgc aggtcaccag ttagctaatt
     2401 cttattttgc catggtcaat ggcggttggt ttggtctagg tcttggaaac tcgattgaaa
     2461 aacgaggtta tttgccagaa gctcatacag actttgtctt ttctatcgtg attgaagaat
     2521 ttggctttgt tggtgccagt cttattttag ctctcttgtt tttcatgatt ttgcggatta
     2581 tcttggtcgg tatccgagcg gagaatcctt tcaatgccat ggttgcactc ggtgtcggag
     2641 ggatgatgtt ggttcaggta tttgtcaata tcggagggat ttcgggcttg attccatcta
     2701 caggagtgac tttccccttc ttatcccagg gtggaaatag tcttctagtc ttatcagtgg
     2761 cagtagcctt tgtcttaaat attgatgcca gtgaaaaacg cgctaaattg taccgagaat
     2821 tggaaaatca accaatgaac cttctgttga agtaggataa agaaaggata gtttatgtct
     2881 cttcaaaaat tagaaaatta tagtaataaa agtgttgtgc aagaagaagt cttgattcta
     2941 acagaattac tggaagatat tactaaaaat atgcttgccc cagagacctt tgaaaaaata
     3001 atacagttga aagaattatc aacgcaggaa gattatcaag gtctaaaccg tctagtgact
     3061 agcttatcaa atgatgaaat ggtctatatt tcacgctatt tctctatctt gcctcttttg
     3121 attaatattt cagaggatgt ggatttagct tatgaaatca atcatcaaaa taatattgat
     3181 caggactatt taggtaaatt atctacaacg attaaattgg tagcagaaaa ggaaaatgcc
     3241 gttgagatcc tagaacactt gaatgttgtc cctgttttga cagcccatcc aacacaagtg
     3301 caacgcaaaa gtatgttgga tttaacaaat catattcata gtcttttgcg taaataccgt
     3361 gatgttaagt tggggttgat caataaagat aaatggtaca atgatttgcg tcgttacatc
     3421 gaaattatca tgcagacaga catgattcgt gagaaaaaat taaaagtgac taacgaaatc
     3481 acgaatgcta tggaatatta taacagctcc tttttgaaag ctgtacctca tttgacgacg
     3541 gagtataagc gcttagcgca agcgcatggt ctgaatttaa aacaggctaa accaatcacc
     3601 atgggtatgt ggataggtgg tgaccgtgat ggaaatccat ttgttacagc aaagaccttg
     3661 aagcagtctg cactcactca gtgtgaagtc atcatgaact actatgataa aaagatttac
     3721 caactttatc gtgaattttc tctttcaact agcattgtca acgtcagcaa gcaagtcaga
     3781 gaaatggctc gtcaatccaa ggataactcg atttaccgcg aaaaagagct ttaccgtcgt
     3841 gccttgtttg atattcaatc aaaaattcag gcaactaaaa cctatctgat tgaggatgaa
     3901 gaagttggga ctcgttatga aaccgccaat gatttctaca aggatttgat tgccattcga
     3961 gattctctac tagaaaataa gggcgagtcc ttgatttcag gtgattttgt ggaattattg
     4021 caggcagtag agatatttgg tttttactta gcatcaattg atatgcgaca agactctagc
     4081 gtctatgaag cctgtgtggc agaactcttg aaatcagcag gaattcattc tcgttatagc
     4141 gagttgagcg aagaagaaaa gtgtgacctt ctcttgaaag aattagaaga agatccccga
     4201 attctttctg cgactcacgc agaaaaatca gaattattag caaaagaact agctattttt
     4261 aagacggctc gtgttttgaa agataagttg ggagatgatg tcatccgtca gaccatcatt
     4321 tcacatgcaa ccagcctttc tgatatgcta gaattagcta ttctgttaaa agaagtagga
     4381 ctggtggata cggaaagggc gcgtgttcag attgttcccc tttttgaaac aattgaagac
     4441 ttggatcatt cagaggaaac aatgagaaaa tatctttctc ttagccttgc caaaaaatgg
     4501 attgactcac gaaataacta tcaagaaatc atgcttggct actctgacag taataaagat
     4561 ggcggttact tgtcatcatg ttggaccctc tacaaggctc aacaacaatt gactgctatt
     4621 ggagatgaat ttggcgttaa ggttaccttc ttccatggtc gtggtggtac tgtcggtcgt
     4681 ggtggtgggc caacctatga agccattaca tctcaaccgc tcaagtctat caaggatcgt
     4741 atccgcttga cggagcaggg tgaagtaatt gggaataaat acggtaacaa agacgccgct
     4801 tactataacc ttgaaatgct agtatcggca gctattaacc gtatgattac tcagaagaag
     4861 agcgatacca ataccccaaa tcgttatgaa gccattatgg atcaagtagt ggaccgtagt
     4921 tacgatatct accgtgattt ggtctttggt aatgagcatt tctatgatta tttcttcgag
     4981 tcaagtccaa tcaaggctat ttcaagtttt aatattggtt ctcgtccagc cgctcgtaag
     5041 actattactg aaatcggtgg attgcgtgct atcccttggg tattctcatg gtcacagagt
     5101 cgtgttatgt tccctggatg gtacggggtt ggttcaagct tcaaggaatt tatcaataaa
     5161 aatccagaga atattgctat cttacgagat atgtaccaaa attggccttt cttccaatcg
     5221 cttctttcaa atgttgatat ggttttgtca aaatcaaata tgaatattgc ttttgaatat
     5281 gctaaacttt gtgaagacga gcaagttaag gccatctatg agactatttt aaatgaatgg
     5341 caagttacta agaacgttat cttggctatt gaaggacatg acgaactctt agctgacaat
     5401 ccatatctaa aagctagtct ggattaccgt atgccttact ttaatattct caactatatt
     5461 cagttagagt tgattaaacg ccaacgtcgt ggagaattgt ccagtgatca agaacgattg
     5521 attcatatca ccatcaacgg aattgcgaca ggattgcgta attcaggttg ataattttca
     5581 agagtgaatg ctaaaagtga atatcaaaaa aattctaata gactattgac aagtagttta
     5641 aaaatgatat aatttaacca ttcagaaaag taatcataca aactttttag agagtctgtg
     5701 gtagctgaaa acagataagt ggcaatgatg aaaattgggc tgaatgctat ttagaatttg
     5761 aaattataaa aattcggtaa gcacacctta cagtgcatct cgttattgcg agactgagcg
     5821 atagggaaat tccctataat tgaggtggta ccgcgcatcg acgtcctcac acaagttttt
     5881 tgtgtgagga tttttttgat ggaggttagt atagaaagaa aacgatggcg tcgcttgttt
     5941 agataagtga aatatgttaa aggaaataaa aaggagaaac agaatgaaaa ataaacgttt
     6001 aattggaatt attgctgcat tagcagtctt agtagcagga agcttgattt attcttcaat
     6061 gaataaatca gaagctcaga ataataagga tgagaagaaa ataaccaaga ttggtgtgct
     6121 tcaatttgtg agccatccat cccttgattt gatttataaa gggatccaag atggacttgc
     6181 agaagaagga tataaagatg atcaagttaa aattgatttt atgaactcag aaggtgacca
     6241 aagtaaggtt gcgacaatga gtaaacaatt ggttgcaaat gggaatgacc ttgtggttgg
     6301 tatcgcaaca ccagcagccc aagggttggc tagtgcaaca aaagacctac cggttatcat
     6361 ggccgctatt acagacccaa ttggtgctaa cttggttaaa gatttgaaaa aaccaggtgg
     6421 caacattaca ggggtatctg accacaatcc agctcaacaa caagttgaac tcatcaaggc
     6481 tctgacaccg aatgtgaaaa caatcggagc tctttactca agtagcgaag acaattcaaa
     6541 aacacaggtc gaagaattta aggcttatgc tgaaaaagca ggtctgacag tggaaacatt
     6601 tgcagttcct tcaacaaatg aaattgcctc aactgtcact gttatgacta gcaaggtaga
     6661 tgctatttgg gttccaattg ataacaccat tgcatcagga tttccaacgg ttgtctctag
     6721 caatcaaagt tctaagaaac caatttatcc cagtgcgaca gctatggtag aagtaggtgg
     6781 tttggcatca gttgtaattg accaacatga ccttggtgtg gcaacaggta aaatgattgt
     6841 gcaagtcttg aaaggtgcaa aaccagccga taccccagtc aatgtctttt caactggtaa
     6901 gtcagtcatc aataaaaaaa tagcacaaga actaggtatt actattcctg agtttgttct
     6961 caaagaagca ggacaagtca tcgaataaat aaggtaggga ggaggagact cttcccattt
     7021 tttaaaaaga tgaatataga aaggattaaa taaaatatga ttgtttccat tatttctcaa
     7081 ggatttgtct gggctattct aggtctggga atctttatga catttaggat tttaaacttt
     7141 ccagatatga cgacagaagg ttccttccct cttgggggag ctgttgctgt cactttgata
     7201 accaaaggcg tgaacccatt tttagcgaca cttgttgctg taggagcagg ttgtttggct
     7261 ggaatggcag caggccttct ttatacaaaa gggaagatcc caaccttgct ctcagggatt
     7321 ttggtgatga cttcttgtca ctcaatcatg ctcttgatta tgggacgtgc aaatttaggc
     7381 ctgcttggaa ccaagcaaat tcaggatgtt ttgccttttg attcggattt gaatcaactc
     7441 ttgacaggtc tcatctttgt gagtattgtt attgctctca tgctcttttt cttggacact
     7501 aaactcggac aagcctatat tgctacaggg gataatcctg atatggctag aagtttcggg
     7561 attcatactg gacacatgga gctcatgggc ttggtcttat caaatggtgt gattgccctt
     7621 gcaggtgccc tcattgctca gcaagaaggt tatgccgatg tgtctcgagg gatcggggtt
     7681 atcgttgtgg ggcttgcaag tttgattatt ggagaagtta ttttcaagag tttgagcttg
     7741 gcagagcgtt tggttactat cgttgtaggt tctatcgctt atcaattttt agtgtgggca
     7801 gttatcgcac ttggctttaa tacaagttac cttcgtttat acagtgcctt gattttagca
     7861 gtctgcctca tgattccaac atttaagcaa acaatcttga aaggagccaa gttaagcaaa
     7921 tgacagcaat tgtagaatta aaaaatgcaa ccaaaatcgt taaaaatggc tttgatgaag
     7981 aaaagattat tttaaatgat gtttccttag aaatttttga acaggacttt atcacgattt
     8041 tgggtggaaa tggtgctggt aaatcaaccc tctttaacac tattgcagga accatatcac
     8101 taaccagtgg aactatccgt attttaggtg aggatgttac caagttttca ccagagaagc
     8161 gcgctaagta tctgtctcga gtcttccaag atccaaagat ggggacagct cctcgtatga
     8221 cagtggcaga gaatctcctg attgccaagt ttcgtggtga aaagcgtgga ctatttccga
     8281 gacgtctggc tagctataag gataagtttc aggcgaccat tgaaaaagtg ggaaacggtc
     8341 ttgagaaaca cttgaataca ccgattgagt tcttatctgg tggacaaaga caggctttga
     8401 gtctcttgat ggcaaccttg aagcgacctg aattactctt gttagacgag catactgctg
     8461 ccctggatcc aaagactagt gttgctttga tggaattgac agatgaattt gttaagaaag
     8521 atcaattgac agcccttatg attacccatc atatggaaga tgctctcaaa tatggcaatc
     8581 gcttgattgt catgaaagaa ggacgggtta tccaagattt gaaacaagaa gaaaaagcaa
     8641 aaatgaaaat ctctgattat tatcaactct ttgaataaag tagggaaaat gagtgaaatg
     8701 gtttactttt tttctgaaat aaagtatact atataaagta aactatgata acatggaggt
     8761 attgtgtatg gttgacaaac aagtcattga agaaatcaaa aacaatgcca acattgtgga
     8821 agtcatagga gatgtgattt ctttacaaaa ggcaggacgg aactatctag ggctctgtcc
     8881 ttttcatggt gaaaaaacac cttctttcaa cgttgtagag gacaagcagt tttaccactg
     8941 ttttggttgt ggtcgctcag gtgatgtctt taaattcatc gaggagtacc aaggggttac
     9001 ctttatggag gctgtccaaa tcttaggtca gcgtgtcggg attgaggttg aaaaaccgct
     9061 ttatagtgaa cagaagccag cctcgcctta ccaagctctt tatgatatgc acgaagatgc
     9121 ggctaaattt taccatgcta ttctcatgac aacgactatg ggcgaagagg ccagaaatta
     9181 cctttatcag cggggtttga cagatgaagt gcttaaacat ttttggattg gtttagcacc
     9241 tccagaacga aactatctct atcaacgttt gtctgatcag tatcgtgaag aggatttact
     9301 ggattcaggc ctgttttatc tctcggatgc caatcaattt gtagacacct ttcacaatcg
     9361 cattatgttt cccctgacaa atgaccaagg aaaggtcatt gccttctcag gtcgtatctg
     9421 gcaaaaaacg gattcacaaa cttctaagta taaaaacagc cgatcgactg caatttttaa
     9481 caaaagttac gaattatatc atatggatag ggcaaaaaaa tcttctggaa aagctagtga
     9541 gatttacctg atggaaggat tcatggatgt tattgcagcc tatcgggttg gaatcgaaaa
     9601 tgctgtggcg tcgatgggaa cggccttgag tcgagagcat gttgagcatc tgaaaaggtt
     9661 aaccaagaaa ttggttcttg tttacgatgg agataaggct gggcaagccg cgatattgaa
     9721 agcattggat gaaattggtg atatgcctgt gcaaatcgtc agcatgcctg ataacttgga
     9781 tcctgatgag tatctacaaa aaaatggtcc agaagacttg gcctatctat taacgaaaac
     9841 tcgtattagt ccgattgagt tctacattca tcagtacaaa cctgaaaaca gtgaaaatct
     9901 gcaggctcag attgagttta ttgaaaaaat agctcccttg attgttaaag aaaagtccat
     9961 cgctgctcaa aacagctata ttcatatttt agctgacagt ctggcgtcct ttgattatgc
    10021 ccagattgag cagattgtta atgagagtcg tcaggtgcaa aggcagaatc gcatggaaag
    10081 aatttccaga ccgacgccaa tcaccatgcc tgtcaccaag cagttatcgg ctattatgag
    10141 ggcagaagcc catctactct atcggatgat ggaatcccct cttgttttga acgattaccg
    10201 tttgcgagaa gactttgcat ttgctacacc tgaatttcag gtcttatatg acttgcttgg
    10261 ccagtatgga aatcttcctc cagaagtttt agcagagcag acagaggaag ttgaaagagc
    10321 ttggtaccaa gttttagctc aggatttgcc tgctgagata tcgccgcagg aacttagtga
    10381 agtagagatg actcgaaaca aggctctctt gaatcaggac aatatgagaa tcaaaaagaa
    10441 ggtgcaggaa gctagccatg taggagatac agatacagcc ctagaagaat tggaacgttt
    10501 aatttcccaa aagagaagaa tggagtaata atggcaacaa aacaaaaaga agtaacaaca
    10561 tttgacgtac aggtagcaga atttatccgt aatcataagc aaaaagggac agcaacagat
    10621 gatgaaatca atgcaagtct ggttattcct tttaccttgg acgctgatgg gattgaagat
    10681 ctcttgcaac ggattcagga tgcaggcatt tctatcacag ataacgaagg aaatccaagt
    10741 gcgcgtgttc ttagcaatga agaagaacca gaactcagcg atgaggactt gattgggtca
    10801 acttctgcta aggtcaatga ccctgtccgt atgtacttga aagaaatagg ggtcgttcct
    10861 ctcttgacca atgaagagga gaaagagttg gcactggctg ttgaagctgg cgatatcgaa
    10921 gccaaacaac gtcttgcgga agccaatctt cgtttggttg tttccattgc caaacgctat
    10981 gtcggtcgtg gcatgcagtt ccttgacttg attcaagaag gaaatatggg cttgatgaag
    11041 gcggttgaca agtttgacta ttctaaaggg ttcaagtttt caacttatgc aacttggtgg
    11101 attcgtcagg ctatcactcg tgctattgcg gaccaagctc gtaccatccg tatcccagtt
    11161 cacatggttg aaactatcaa taaattggtt cgtgaacagc ggaatctcct tcaagaattg
    11221 gggcaagatc cgacaccaga acagattgct gaacgaatgg atatgacacc tgataaggtt
    11281 cgtgaaatct tgaagattgc ccaagaacca gtatctcttg aaactcctat cggtgaagag
    11341 gacgatagcc accttggaga ctttatcgaa gatgaagtga ttgaaaatcc agtggattat
    11401 acgactcgta tcgtcttgcg tgagcaattg gatgaaatct tagatactct tacagaccgt
    11461 gaagaaaatg ttctgcgtct acgttttgga ctagatgatg gaaaaatgcg cacacttgaa
    11521 gatgtgggga aagtctttaa cgtaactcgt gagcgtatcc gtcagattga agcaaaggct
    11581 ttgagaaaac tacgccaacc aagtcgcagc aaaccgcttc gtgattttat tgaagactaa
    11641 gagtgaggaa aatatggctt atacagaaga gcaaattgaa aacatcaaaa cacggatttt
    11701 aacagccttg gaagaagtca tcgaccctga gttgggaatc gatattgtca atcttggttt
    11761 gatctatgag attcgttttg acggtgacac agggcaaaca gagattgaca tgactttgac
    11821 aactatgggt tgtcccttag cagacctttt gacagaccag atttatgatg ctatgataga
    11881 ggttccagaa gtaacggata ctgaggttaa attagtctgg tatccagcct ggacagttga
    11941 aaaaatgagt cgctatgccc gcattgccct aggcattaag taaacatata aaagcatgtg
    12001 agagactgtt ggaaaagcga ggaaatttcc cctcttttcc tctagtctct cctttctttt
    12061 gctgatttta ttcaaagaaa atgatataat agtagttatg gagaaaaaga aattacgcat
    12121 caatatgttg agttcaagtg agaaagtagc aggacaggga gtttcaggtg cttaccgtga
    12181 attagttcgt cttcttcacc gtgctgccaa ggaccaattg attgttacag aaaatcttcc
    12241 gatcgaggca gatgtgactc actttcatac gattgatttt ccctattatt tatcaacctt
    12301 ccaaaagaaa cgctcaggga gaaagattgg ctatgtgcat ttcttgccag ctacacttga
    12361 gggaagtttg aaaattccat ttttcttaaa gggaattgtg aaacgctatg tattttcttt
    12421 ttacaaccgg atggagcact tggttgtggt caatcctatg tttattgagg atttggtagc
    12481 agctggtatt ccacgtgaaa aagtgaccta tattcctaac tttgtcaaca aggaaaaatg
    12541 gcatcctcta ccacaagaag aggtagtcag actgcgcaca gatcttggtc ttagtgacaa
    12601 tcagtttatc gtagtaggtg ctgggcaagt tcagaaacgt aaagggattg atgactttat
    12661 ccgtctggct gaggaattgc ctcagattac ctttatctgg gctggtggct tctcttttgg
    12721 tggtatgaca gatggttatg aacactataa gaaaattatg gaaaatcccc ctaaaaattt
    12781 gatttttcca ggcattgtat cgccagagcg gatgcgcgaa ttgtatgctc tagcggatct
    12841 tttcttgttg cctagttaca atgagctctt tcctatgact attttagaag ctgcgagttg
    12901 tgaggctcct attatgttgc gtgatttaga tctctataag gtgattttgg agggaaatta
    12961 tcgggcgaca gcgggtagag aagagatgaa agaggctatt ttggaatatc aagcaaatcc
    13021 tgctgcctta aaagatctca aagaaaaggc taagaatatt tccagagagt attctgaaga
    13081 gcatctgtta caaatctggt tggactttta tgagaaacaa gccgctttag ggagaaagta
    13141 aaaagtgagg taatctatgc gaattggttt atttacagat acctattttc ctcaggtttc
    13201 tggtgttgcg accagtattc gaaccttgaa aacagaactt gaaaagcagg gacatgctgt
    13261 ttttatcttt acgacgacag ataaggatgt caatcgctac gaagattggc aaattatccg
    13321 cattccaagt gttcctttct ttgcttttaa ggatcgtcgc tttgcctacc gaggttttag
    13381 caaggcactt gaaattgcta aacagtatca gctagatatt atccatactc agacagaatt
    13441 ttctcttggc ctgttgggga tttggattgc gcgtgaattg aaaattccag tcatccatac
    13501 ctatcacacc cagtatgaag actatgtcca ttatattgct aaggggatgt tgatccgacc
    13561 gagtatggtc aagtatctgg ttagaggttt cctgcatgat gtggatgggg ttatttgccc
    13621 tagtgagatt gtccgtgact tgctatctga ttataaggtc aaggttgaaa aacgggtcat
    13681 tcctactggg attgaattag ccaagtttga gcgtccggaa atcaagcagg aaaatttgaa
    13741 agaactgcgt agtaaactag ggattcaaga tggtgaaaag acgttgctta gtctttcgag
    13801 aatctcctat gaaaaaaata ttcaagcagt tttagtagcc tttgctgatg ttctgaaaga
    13861 ggaagacaag gttaaactgg tagtagctgg ggatggccct tatctgaatg acctcaaaga
    13921 gcaagcccag aacctagaga ttcaagactc agtcatcttt acagggatga ttgctcctag
    13981 tgagacggct ctttactata aagcggcgga ttttttcatt tcggcatcga caagcgaaac
    14041 gcaaggtttg acctacttgg aaagcttagc cagtggaaca cctgtcattg ctcacggaaa
    14101 tccttatttg aacaacctca tcagtgataa aatgtttgga accttgtact atggagaaca
    14161 tgatttggct ggtgctattt tggaagccct gattgcaaca ccagacatga acgagcatac
    14221 cttatcagag aaattgtatg agatttcagc tgagaacttt gggaaacgag tgcatgagtt
    14281 ttatctggat gccattattt caaataactt ccagaaagat ttggctaaag atgatacggt
    14341 cagtcagcgt atctttaaga cagttttgta tcttcagcaa caggtggttg ctgtacctgt
    14401 aaaaggatct agacgcatgt tgaaggcttc aaaaacacag ttgatcagta tgagagacta
    14461 ttggaaagac catgaagaat agaaagagga acagctatga aaaaaacaat taatgagaag
    14521 cggtcgtgat aaaaagattg cgggtgtttg tgctggggtg gcccattatc tggatatgga
    14581 tccgactatc gttcaagtca tttggggtgt tcttacttgc tgttacggag ctggaattgt
    14641 agcttacatt attttatgga ttatcgtacc agtagcaact gactattgaa aactagctca
    14701 attcatgcta agataataga aaatagaatg taacgaagga gagaaaaatg gcatttggag
    14761 ataatggaaa tcgtaaaaaa actatgtttg agaaaataac cttgtttatc gtgattatca
    14821 tgctagtagc aagtttattg ggaatttttg caactgcaat tggtgccctc agtaatctat
    14881 aaaatagatt caagaaaatt tagtgactgg gatttcccag ccctttttta aagtgagaag
    14941 aaataatgag tatgttttta gatacagcta agattaaggt caaggctggt aatggtggcg
    15001 atggtatggt tgcctttcgt cgtgaaaaat atgtccctaa tggaggccct tggggtggtg
    15061 atggtggtcg tggaggcaat gtggtcttcg ttgtagacga aggattacgt accttgatgg
    15121 atttccgcta caatcgtcat ttcaaggctg attctggtga aaaagggatg accaaaggga
    15181 tgcatggtcg tggtgctgag gaccttagag ttcgagtacc acaaggtacg actgttcgtg
    15241 atgcggagac tggcaaggtt ttaacagatt tgattgaaca tgggcaagaa tttatcgttg
    15301 cccacggtgg tcgtggtgga cgtggaaata ttcgtttcgc gacaccaaaa aatcctgcac
    15361 cggaaatctc tgaaaatgga gaaccaggtc aggaacgtga gttacaattg gaactaaaaa
    15421 tcttggcaga tgtcggttta gtaggattcc catctgtagg gaagtcaaca cttttaagtg
    15481 ttattacctc agctaagcct aaaattggtg cctaccactt taccactatt gtaccaaatt
    15541 taggtatggt tcgcacccaa tcaggtgaat cctttgcagt agccgacttg ccaggtttga
    15601 ttgaaggggc tagtcaaggt gttggtttgg gaactcagtt tctccgtcac atcgagcgta
    15661 cacgtgttat ccttcacatc attgatatgt cagctagcga aggccgtgat ccatatgagg
    15721 attacctagc tatcaataaa gagctggagt cttacaatct tcgcctcatg gagcgtccac
    15781 agattattgt agctaataag atggatatgc ctgagagtca ggaaaatctt gaagaattta
    15841 agaaaaaatt gtctgaaaat tatgatgaat ttgaagagtt accagctatc ttcccaattt
    15901 ctggattgac caagcaaggt ctggcaacac ttttagatgc tacagctgaa ttgttagaca
    15961 agacaccaga atttttgctc tacgacgagt ccgatatgga agaagaagct tactatggat
    16021 ttgacgaaga agaaaaagcc tttgaaatta gtcgtgatga cgatgcgaca tgggtacttt
    16081 ctggtgaaaa actcatgaaa ctctttaata tgaccaactt tgatcgtgat gaatctgtca
    16141 tgaaatttgc ccgtcagctt cgtggtatgg gggttgatga agcccttcgt gcgcgtggag
    16201 ctaaagatgg ggatttggtc cgcattggta aatttgagtt tgaatttgta gactaggaga
    16261 ctggtatggg agataaaccg atatctttcc gagatgcgga tggtaatttt gtttccgccg
    16321 cagacgtttg gaatgaaaag aaattggaag aactatttaa tcgtctcaat ccaaatcgtg
    16381 ccttgagatt ggcacgaact aaaaaggaaa atccatctca gtaaagaagc taaaaaatcc
    16441 cggctctttg tcaactgtag tgggttgaag aaaagctaag ctcgagaaag gacaaatttt
    16501 gtcctttctt ttttgatatt cagagcgatg aaaatccgtt ttttgaagtt ttcaaagttt
    16561 cgaaaaccaa aggcattgcg cttgataagt ttgatgagat tattggtcgc ttccagtttg
    16621 gcattagaat agtgtagttg aagggcgttg acaatctttt ctttatcttt gaggaaggtt
    16681 ttaaagacag tctgaaaaat aggatgaacc tgcttaagat tgtcctcaat aagtccgaaa
    16741 agtttctctg gttccttatt ctggaagtga aaaagcaaga gctgatagag ctgatagtga
    16801 tgtttcaagt cttccgaata gctcaaaagc ttgtttaaaa tctctttatt ggttaaatgc
    16861 atacgaaaag taggacgata aaaacgttta tcactcagtt tacggctatc ctgttgaatg
    16921 agtttccagt agcgcttgat agccttgtat tcatgggatt ttcgatgaaa ctgattcatg
    16981 atttggacac gcacacgact catagcacgg ctaagatgtt gtacaatgtg aaagcgatca
    17041 agaacgattt tagcattcgg gagtgaaaca gtctgggaga ctgtttcagc ctgagcctag
    17101 aaatttgaaa gcgaagctgt ttagccaagc catagtaagg gctaaacata tccatggtaa
    17161 tgattttgac gcgacatcgg acggctctat catatttaag aaagtgatct cggatgacag
    17221 cttgtgttct gccttcaaga acagtgatga tattgagatt gttaaaatct tgcgcaataa
    17281 agctcatctc catctcccga ttgaaacagt cactccccgg actgtttcaa cgtcccagga
    17341 cataatctca ggaagacaag aaaaatcatg tttaaagtga aaatcattga gcttacgaat
    17401 aacagttgaa gttgaaatgg ccagctgatg agcaatatcg gtcatagaaa tcttctcaat
    17461 caacttttgc gcaatttttt ggttgataat acgaggaatt tggtgatttt tcttgacgat
    17521 agaagtttca gcgaccatca tttttgaaca gtgatagcac ttgaatcgac gctttctaag
    17581 gagaattcta gtaggcatac cagttgtctc aaggtaagga atcttagacg gtttttgaaa
    17641 gtcatatttc ttcaattggt ttccgcactc agggcaagat ggtgcgtcgt agtccagttt
    17701 ggcgatgatt tccttgtgtg tatctttatt gatgatgtct aaaatctgga tattagggtc
    17761 tttaatgtct agtaattttg tgataaaatg taattgtccc atatgaatct ttctaatgag
    17821 ttgttttgtc gcttttcatt atagatctta tgggattttg tggtacgaca ggcatgtata
    17881 gcaaactgaa tctggaatag cacagcatat cttctaaaat attgttataa attgatttga
    17941 atttcaaaat taaattgttt gattcttatt tcaatttgtt atagtatatc tgatgtcaaa
    18001 gttctcggcg aatcaaatag cgattcccaa gcctgactat cgtgaggtag cggattaaaa
    18061 tggtctgggg atagaccgtt ttaagtctga cgctggaaat aagaattgtc agaagaaggg
    18121 atagcgaaat cgtggctcta cgaacaggaa cgtgataata aggcgtatat agcggataag
    18181 agggcctcaa actctaaagt ccaaaaaggt agtcgtaacc tatatgcgta aatcacgaga
    18241 gtaattgaat tcgtactaag attttctatt ttcactgtaa ccttttaacg tcctcatatc
    18301 ttgtatacac gaggaaagat gtacgactta tcccgtgagg tctatcacta taaagagaaa
    18361 acgacagata gaagtgatcc tgagtcacgg ttatctttaa aatagattgt ctgataggat
    18421 gctagcctga aaacgtcttg ttcatgaaat ataggacggt atgtataaaa cgcttctgtg
    18481 aactgagaga agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatat
    18541 ttagataaga gatctagtct tagctcctac tcggtttcag gggataaaaa aggggcaata
    18601 gcgattcgag aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg
    18661 ccgtacgtgt aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga
    18721 gcaacctgcg gctagtttcc tagtgtgatc tttgattttt attgagtatt agtaattcag
    18781 ttactaactc gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa
    18841 atttatgata tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact
    18901 tagaatgaga aaaattgtta tcaatggtgg attaccactg caaggtgaaa ttactattag
    18961 tggtgctaaa aatagtgttg tggccttaat tccagctatt atattggctg atgatgtggt
    19021 gactttggat tgtgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt
    19081 gatgggagct actgttaagc gttatgacga tgtcttggag attgatccaa gaggtgttca
    19141 aaatattcca atgccttatg gtaaaattaa cagtcttcgt gcatcttatt atttttatgg
    19201 gagcctctta ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg
    19261 tcctcgtccg attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta
    19321 cgagggagat aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta
    19381 catggatacg gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa
    19441 tggtcgtact attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct
    19501 cttgaataat atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg
    19561 tgttgaaaga ttacatggga cacgtcatca ggtgattcca gaccgcattg aagctggaac
    19621 atatatatct ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga
    19681 acacctggaa gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga
    19741 agacagcatt tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc
    19801 ttacccaggc tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa
    19861 tggtcgtggt acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact
    19921 agcaaagatg gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg
    19981 tgatttacgt ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat
    20041 tgctgggctt atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg
    20101 ttattctgat attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga
    20161 ttaaaccgta gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga
    20221 aacggatcgc ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat
    20281 agcttcaaat ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag
    20341 tcaatatgca ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga
    20401 ccagaaaaat caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa
    20461 agaagctgag cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga
    20521 ggttgttaga aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatctat
    20581 cattacccac cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt
    20641 gttccgtcag tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt
    20701 tcggtatgta aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg
    20761 aattaccagt aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg
    20821 atggaacagc ctatcgggct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc
    20881 ctagaagtgg aacaattcgt gttaaatccc agaaagttgc tatagagaga ttaacgtttg
    20941 ctgaaattgc agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag
    21001 aatttagtaa gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg
    21061 atggggggct cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg
    21121 aaaatgcagt tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca
    21181 atcaaaaagg gattcctgtt ctaagaagta agcatgatac ctttaccgtc gcgaccatga
    21241 tcaataaagc cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt
    21301 atcgccctag tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg
    21361 acttggttcg taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg
    21421 ttggtgttgt aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg
    21481 ttatgtctcg tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac
    21541 ggatgatcgc agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg
    21601 gcgttgtgac gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac
    21661 caactttttc tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta
    21721 cagtggaacc ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa
    21781 ttctgaccca catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc
    21841 agatgctgat ctactttttg caggctgttc agatagatga tatattgcgc attcaggcac
    21901 ggattattca tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc
    21961 agattgtttc aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga
    22021 taacattaaa atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa
    22081 gtattcatat aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag
    22141 aatatgtccg ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg
    22201 gtgccatgat ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg
    22261 ctttccctcg tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg
    22321 gaggtcccat tgctaaatct gacctgaatg tctcaaaatt aaacttcaac aatgttgaac
    22381 aaatgaaaaa atacactcag agctattctg gtggtttagc agactcatgt tgggcttatg
    22441 ctgttggtac accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt
    22501 acaagggtat tgagcaagct gttattggaa atcgtatcgg tgatatcggt gcggctattc
    22561 aagaatacgc tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg
    22621 gcccaactat gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc
    22681 gtcttcgtga aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa
    22741 ttgatacaga tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc
    22801 agtatgaaca ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg
    22861 aagaaggaac ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc
    22921 agtagatctt ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt
    22981 tttctgcttt taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag
    23041 gattcagggc tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag
    23101 tgtcgcagtc tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga
    23161 gaaatggaat tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag
    23221 acttcctgcg aaacaaaata tggtatagta gttccatgaa ttatgaagca agtaaacaac
    23281 taactgatgc acgatttaag cgtcttgttg gtgttcagcg taccactttt gaagagatgt
    23341 tagctgtatt aaaaacagct tatcaactta aacacgcaaa aggtggacga aaacctaaat
    23401 taagcctaga agaccttctt atggccactc ttcaatatgt gcgagaatat cgaacttatg
    23461 aacaaattgc ggctgatttt ggtattcacg aaagcaactt actccgtcgg agccaatggg
    23521 ttgaagtaac tcttgttcaa agtggtttta cgatttcaag aactcctctc agttctgagg
    23581 acacggtaat gattgatgcg acggaagtaa aaatcaatcg ccctaaaaaa agaattagcg
    23641 aatgattctg gtaaaaagaa atgccacgct atgaaggctc aagcgattgt cacaagtcaa
    23701 gggagaattg tttctttgga tatcgctgtg aactattgtc atgatatgaa gttgttcaaa
    23761 atgagtcgca gaaatatcgg acaagctgga aaaatcttgg ctgacagtgg ttatcaaggg
    23821 ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccgcta
    23881 acagttgaag ataaagccta taaccatgcg ctatccaagg atagaagcaa ggttgagaac
    23941 atctttgcca aagtaaaaac gtttaaaatg atttcaacaa cttatcgaaa tcatcgtaaa
    24001 cgtttcggat tacgaatgaa tttgagtgct ggtattatca atcatgaact aggattctag
    24061 ttttgcagga agtctattga ggtattgagc tagtttatga aaaaattggg tgaaaaagtc
    24121 gagtgtttta gaaacccaca gtgtagtatt ctagtttcaa tccactatat tttgctactc
    24181 cccgtaaagt ttctattttc cctgatttct gatataatag aaatattgac ttcaagagta
    24241 aggaagagaa gatgaacgca ttattaaatg gaatgaatga ccgtcaggct gaggcggtgc
    24301 aaacgacaga aggtcccttg ctaatcatgg caggggctgg ttctggaaag actcgtgttt
    24361 tgacccaccg tatcgcttat ttgattgatg aaaagctggt caatccttgg aatatcttgg
    24421 ccattacctt taccaacaag gctgcgcgtg agatgaaaga gcgtgcttat agcctcaatc
    24481 cagcgactca ggactgtctg attgcgacct tccactccat gtgtgtgcgt attttgcgtc
    24541 gcgatgcgga ccatattggc tacaatcgta attttacaat tgtggatcct ggtgaacagc
    24601 gaacgctcat gaaacgtatt ctcaaacagt tgaacttgga tcctaaaaaa tggaatgaac
    24661 gaactatttt ggggaccatt tccaatgcta agaatgattt gattgatgat gttgcttatg
    24721 ctgcccaagc tggcgatatg tatacgcaaa ttgtggccca gtgttataca gcctatcaaa
    24781 aagaacttcg tcagtctgaa tccgttgact ttgatgattt gattatgctg accttgcgtc
    24841 tctttgatca aaatcctgat gttttgacct actaccagca aaaattccaa tacatccacg
    24901 ttgatgagta ccaagatacc aaccacgctc agtaccaatt ggtcaaactc ttggcttccc
    24961 gttttaaaaa tatctgtgtg gttggggatg cggaccagtc tatctacggt tggcgtggtg
    25021 ctgatatgca gaatatcttg gactttgaaa aggattaccc caaagccaag gttgttttgt
    25081 tggaggaaaa ttaccgctca accaaaacca ttctccaagc ggccaacgag gttattaaaa
    25141 acaataaaaa tcgccgtcct aaaaatctct ggactcaaaa cgctgatggg gagcaaatcg
    25201 tttactatcg tgccgatgat gagctggatg aggctgtatt tgtagccaga accatcgatg
    25261 aacttagtcg cagtcaaaac ttccttcata aggattttgc agttctctat cggactaatg
    25321 cccagtcccg tacaattgag gaagccctgc tcaagtctaa cattccttat accatggttg
    25381 gcggaaccaa attctacagc cgtaaggaaa ttcgcgatat tattgcttat ctcaacctta
    25441 ttgctaattt gagtgacaat attagttttg agcgtattat caacgagcct aaacgtggaa
    25501 ttggtccagg tacagttgag aaaatccgtg attttgcaaa tttgcaaaat atgtctatgc
    25561 tggatgcttc tgctaatatt atgttgtctg gtatcaaggg taaggcagcc caatctatct
    25621 gggattttgc caatatgatg cttgatttgc gggagcagct agaccactta agcattacag
    25681 agttggttga gtccgtccta gaaaaaacag gttatgtcga tattcttaac gcccaagcga
    25741 ctctagaaag caaggcacgg gttgaaaata tcgaagagtt tctttctgtt acgaagaact
    25801 ttgatgacac cacggatgtg acagaagagg aaactggtct ggacaaactg agtcgtttct
    25861 taaatgactt ggctttgatt gccgacacag attcaggtag tcaggagaca tcagaagtga
    25921 ccttgatgac cctgcatgct gccaaaggtc tcgaatttcc agttgtcttt ttgattggga
    25981 tggaagaaaa tgtctttcca cttagtcgtg cgactgaaga tccagatgaa ttagaagaag
    26041 agcgccgtct agcctatgta ggtatcacgc gtgcagagaa aattctctat ctgaccaatg
    26101 ccaactcacg cttgcttttt ggtcgtacca attataaccg tccgactcgt tttattaacg
    26161 aaatcagttc agacttgctt gagtatcaag gtctggctcg tcctgcaaat acaagcttta
    26221 aggcatcata tagcagtggt agtatttcct ttggtcaagg tatgagtttg gctcaggctc
    26281 ttcaagaccg taaacgcggt gctgccccaa aatcaatcca gtcaagcggt cttccatttg
    26341 gtcaatttac agctggcgca aaatcagcat ctagcgaggc aaattggtcc attggtgaca
    26401 ttgctctcca caagaaatgg ggagagggaa ctgttctgga agtttcaggt agcggtgcta
    26461 ggcaggaatt gaaaatcaat ttcccagaag taggtttgaa aaaactttta gccagtgtgg
    26521 ctccaattga gaaaaaaatc taattttcca tccttctcac gaataataaa gtgaggagga
    26581 tttttatgta cagtatttca ttccaagaag attcactatt accaagagaa aggctggcca
    26641 aggaaggagt tgaagcgctt agtaaccaag agttgctagc tattttactc aggacaggaa
    26701 cacgtcaagc tagcgttttt gaaattgccc aaaaagtctt gaacaatctt tcaagcctaa
    26761 cggatttgaa aaaaatgacc ctgcaggaat tgcagagttt gtctggtatt gggcgtgtta
    26821 aggccataga attacaagct atgattgaac tggggcatcg tattcacaaa cacgagactc
    26881 ttgaaatgga aagtattctc agcagtcaaa agttggccaa gaagatgcag caggaattag
    26941 gggataaaaa acaagagcac ctggtggcac tctatctcaa tactcaaaat caaatcatcc
    27001 atcagcagac catttttatc ggttctgtaa ctcgtagtat cgctgaaccg cgagagattc
    27061 tgcactatgc aatcaagcat atggcgactt ctcttatctt ggtccacaat catccttcag
    27121 gagcggtagc gcctagccaa aatgatgatc atgtcactaa acttgttaaa gaagcctgcg
    27181 aattgatggg gattgttctc ttggaccatt tgattgtctc tcattctaat tactttagtt
    27241 atcgtgaaaa gacagattta atctaaagtt cattaacgac atagtcaaag agttttttat
    27301 ctttgggacg attttcaaaa agaagttctg gatgccattg gacaccgaga aaggcgacat
    27361 catccgtact catgacagcc tcaatgatac catctttagg atcatgagcc acaactttta
    27421 aatttggtgc taagtccttg atgctctggt ggtggaagga gttgatatga gagatttctc
    27481 catagatttc ttggagaacg gtatctggtt ctgttaccaa gcgttgagtt gtgtactcaa
    27541 cagaagaatc ctgccaatgg tcttcgatat cttggtacaa agttccaccc atggcaacgt
    27601 taaagagttg ggtaccacgg cagacagaga aaatgggctt tttctgttta atagcttcct
    27661 tgatgagggt cagttcgaag atatctcttt gaaggtgata gtcatcgcta tcaatggttt
    27721 tgggttcgcc ataaaatttt ggatcgacat tttgcccacc tgtcaagatg agcttgtcaa
    27781 tcaaactgat atagtggcag gccatttctt gatcaccaat cggtaggatg atgggaatcc
    27841 ctccagaatc tttaacgcct tcaacaaagc cttttgctgc gtagctcatc atgatgtcat
    27901 catctggatg agctttttcg tttcctgtaa tcccaataac tggttttttc ataaaatgat
    27961 tttcgctttc taatcctctt ttcgcatgaa gtagaggagg gtttggagtt cacttgtcaa
    28021 atcgacatac tgaacgacca cgtcttttgg taaatgcaga tggactggtg aaaaactgag
    28081 aattcctttc acaccagcat caaccaagag attagcaacc tcttgtgact tgacgctggg
    28141 aacagttagg atagcagtct tcacatcagc atccttgatt ttatccttga tctgagaaat
    28201 cccgtaaatg ggaatcccgt caggagtttg ggtaccgact tcaggatggt cgtctaggtc
    28261 aaaggccatg ataatcttca tcttgttacg ttcgtggaag cggtagtgga gaagggcatg
    28321 gcccatattt ccaataccaa ccagcatgac attggtaata gagttgtcat tgagcaaatc
    28381 ggcaaaaaat gtcattagtt ttttgacatc atagccaaaa ccacgacgac caagttcacc
    28441 aaaataggaa aaatcacgac gtacggtcgc tgaatcaata ccgatagcct ctgcaatttg
    28501 cttagagttg gcacgttcaa tcttttctgc atgaaatctc ttaaaaattc gatagtagag
    28561 agagagtctt tttgctgtag cttttggaat agcaaactgt ttatctttca caaaatcaca
    28621 acctttctat tcttctattt tatagaaaca ttgtgaaaaa atcaacaaaa ataagaaaaa
    28681 actaagaaaa atcttagttt tgatgtaaaa aatctgcatg agatagaaaa cggtagaggt
    28741 ctccgaccag accctgataa actttttggc ccctaaaagt cagagaagtc acataaagtg
    28801 tatctggtaa ggttacacat cctgacaaag tcaacatgag agcctcatga tcctcatact
    28861 tgagagtacg ctctacatga tagcagtcct tataggtcag ttcaaacatt ttggctctat
    28921 ctttccgatt ttgtaaagac accacgttct accaagctat ccatgaggaa gtagaatttt
    28981 tcctgatgaa tatggtggtc ttctgatttg aaaatatcaa ctagacgaag gccaaacttg
    29041 tcagtgatat tgattttagc ccctgtaagt tccttgttaa tgatgatttt gagttggaag
    29101 ccttcaccgc tgtttggcac tttttccaaa aggcgagtca gttcatagtt accaacctta
    29161 gtttcaaaaa aggtgttatc tttgagggtg aattttttaa cagaagggct aagagtgtaa
    29221 tcgtaacgac aattttttaa ctgaatgatt ttttcaaatg ccatatggct aacctccgat
    29281 aatttctttt aaggtttttg cgagggtttg taggtcttca acggtatttt gtggcgacaa
    29341 actgatgcga agggattcct tcaagcgttc tgaatttgcg ccatacatgg cttcaagaac
    29401 atggctggat tggacaacgc ctgcagtaca ggctgagcca gtagagattg aaattccagc
    29461 taaatctagc cgaaggagta agaggtcatt tttctgacca ggaaatccaa tattgagaac
    29521 ataagggaga tgatgttttc ctctattcaa gtaatactga atgccctcca gctctgccag
    29581 aaaggcagtt tctagatttt gtacatgttg aaaatgttct tcttgttttt ctaggtcttc
    29641 ttttagggct gcaaccatgc ctacgatagc aggcagattt tcagttcctg cacgtttttt
    29701 ctgttcctgg tctccgccat gtagatagga atcaaagtcc atgctagatg cgtagagaaa
    29761 accgattccc ttaggaccat ggaatttgtg ggcagaagca gtgagaaaat caatgcccaa
    29821 ttcttctgaa tgaattggga ttttaccaat agcctgaact gcatcaacat gataggcagc
    29881 agggtgttgc ttgagtattt ggccaatttc agcgatgggc agtaggtttc ctgtctcatt
    29941 attggcaaac atggtagaaa ccaaaatcgt atcgtcacgt aaagcctttt gaatttgctg
    30001 ggctgtgatt tcttgatttt ctggctggat aatggttgct tcaaacccaa agtgttgaac
    30061 caagtaatca attgtttcaa ggacagcatg gtgctcgatg gcagttgtga tgatatgttt
    30121 tccttgttct tggtgacgaa gacagtagcc aatgatggta gtattattgc cttcagtccc
    30181 accagaagtg aaaaagatat gttgaggttt tgtccttagt aactgggcta gttcctgacg
    30241 ggcttctcgc aagagtttgc cagcttgacg accatgacca tgaatactag aaggatttcc
    30301 gtgggtttct tgcataacct tggtcatagc tgaaatagca actgctgaca taggagtcgt
    30361 tgcagcattg tccaaataaa tcaaagaatc accttatttc tttttattgt aggcaaagag
    30421 tgggctgact ggttttcttt cgtgaatacg gacgatagca tcaccaatta actcactagc
    30481 agtgatgtag catacatttt taggagtttt ttcttttgtt gctactgaat cagtcacaag
    30541 aatttcttta atattagtat tgtcaagaag ctcagcagct ccctcgacga agagaccgtg
    30601 gctagaaaca gcataaattt ctgtagctcc ttcacgttca acgattttag aagcttcaga
    30661 gaaggtacgt cctgtattta aaatatcatc aatcaagata gctttcttac cttcaacatc
    30721 accaataata taaccttcgt tacgagttgc atcgtcttga gggtagtcga taatggcgat
    30781 aggagcatca agatattcag ccaggctacg cgcacgtttg acacctgaat ttttagggct
    30841 aacgacaaca acatctgaac caagcaatcc tttatcgcag taatgttttg cgaatagggg
    30901 aacagtgaaa agattatcca ctggaatatc aaagaaacct tgaacctgaa cggcatgcaa
    30961 atcaagagtc aggatacgat caactccagc cttaaccagc atattggcaa ctagttttgc
    31021 tgtaagtggc tcacgaggac aagcaatgcg gtcttgacgt gcatagccaa aatatggaag
    31081 gacaacgttg atactgtggg cacttgcacg cacacaagca tcgaccatga ttaacaattc
    31141 cattaggtgg ttgttgacag ggaaacttgt tgattggatg atgtaaacat cataaccacg
    31201 gacactttct tcgatattta cttggatttc tccgtctgaa aattgacgtg atgatagttt
    31261 tccaagtggg gcaccaacag cttgggcaat tttttgtgca atctcttggt tagagttgag
    31321 tgcgaaaagt ttcatgtttt ttctatctga cattatagac cgtcctctgt aaactttata
    31381 aatcctagtt atatttacct tacatatatg aactgggatt tgtgtatttt tatcttttct
    31441 attttaccaa aaaatggaga ttatttcagc tatttttcat acttttgaca aatcgaacca
    31501 attttgaagg agctttttgg taggaaatct gatttttctc taaaaattgt cggaaatcct
    31561 gtttgccttg ctcatgattt tccacttcaa gctccaattc gtaatctgtt atatcaaagt
    31621 atcggctctg atccagtgcc atgagaccaa tagctgtttt catttcatag cgaagcgttg
    31681 ttagacaacc aagaacctgc cagttcttac tttggatacc atgtttcgcc aattcatcca
    31741 gtactagccc ttgaggaagt tcttccttac tcagatagtt ctcagcatct tttagttgca
    31801 atttttggtt gtattccatg tttccaacac tctgcgggac tttgagtgtc aactcagccc
    31861 agtcttcaaa ggttcgaatg cgcatagcga ctttcttttc tcgcagttca aaatcaggcg
    31921 tgtcgatgta gtaatttgtt tgaagaacag gagtgacacc tgtgaactgg tcttttagac
    31981 gattgtattc atcttttttc aatagtgttt tcaattcaat ttctaaatgt ttcatttttc
    32041 ttaccttttt ttatcgttga aagcggattt atggtataat aagcattgta tttattgtat
    32101 atgaatctgg agaaaaaatc aaagatattt ttgacggata atatgagaac aagggagaat
    32161 atatgacctt agaatgggaa gaatttctag atccttacat tcaagctgtt ggtgagttaa
    32221 agattaaact tcgtggtatt cgtaagcaat atcgtaagca aaataagcat tctccaattg
    32281 agtttgtgac cggtcgagtc aagccaattg agagcatcaa agaaaaaatg gctcgtcgtg
    32341 gcattactta tgcgaccttg gaacacgatt tgcaggatat tgctggctta cgtgtgatgg
    32401 ttcagtttgt agatgacgtc aaggaagtag tggatatttt gcacaagcgt caggatatgc
    32461 gaatcataca ggagcgagat tacattactc atagaaaagc atcaggctat cgttcctatc
    32521 atgtggtagt agaatatacg gttgatacca tcaatggagc taagactatt ttggcagaaa
    32581 ttcaaattcg tactttggcc atgaatttct gggcaacgat agaacattct ctcaactaca
    32641 agtaccaagg ggatttccca gatgagatta agaagcgact ggaaattaca gctagaatcg
    32701 cccatcagtt ggatgaagaa atgggtgaaa ttcgtgatga tatccaagaa gcccaggcac
    32761 tttttgatcc tttgagtaga aaattaaatg acggtgtagg aaacagtgac gatacagatg
    32821 aagaatacag gtaaacgaat tgatctgata gccaatagaa aaccgcagag tcaaagggtt
    32881 ttgtatgaat tgcgagatcg tttgaagaga aatcagttta tactcaatga taccaatccg
    32941 gatattgtca tttccattgg cggggatggt atgctcttgt cggcctttca taagtacgaa
    33001 aatcagcttg acaaggtccg ctttatcggt cttcatactg gacatttggg cttctataca
    33061 gattatcgtg attttgagtt ggacaagcta gtgactaatt tgcagctaga tactggggca
    33121 agggtttctt accctgttct gaatgtgaag gtctttctcg aaaatggtga agttaagatt
    33181 ttcagagcac tcaacgaagc cagcatccgc aggtctgatc gaaccatggt ggcagatatt
    33241 gtaataaatg gtgttccctt tgaacgtttt cgtggagacg ggctaacagt ttcgacaccg
    33301 actggtagta ctgcctataa caagtctctt ggcggtgctg ttttacaccc taccattgaa
    33361 gctttgcaat taacggagat tgccagcctt aataatcgtg tctatcgaac actgggctct
    33421 tccattattg tgcctaagaa ggataagatt gaacttattc caacaagaaa cgattatcat
    33481 actatttcgg ttgacaatag cgtttattct ttccgtaata ttgagcgtat tgagtatcaa
    33541 atcgaccatc ataagattca ctttgtcgcg actcctagcc ataccagttt ttggaaccgt
    33601 gttaaggatg cctttatcgg tgaggtggat gaatgaggtt tgaatttatc gcagatgaac
    33661 atgtcaaggt taagaccttt ttaaaaaagc acgaggtttc taagggattg ctggccaaga
    33721 ttaagtttcg aggtggagct attctggtca ataatcaacc gcaaaatgca acgtatctat
    33781 tggacgttgg agactacgtt accattgaca ttcccgctga ggaaggcttt gaaaccttgg
    33841 aggctattga gcatctatta gatattctct atgaggatga tcactttcta gtcttgaata
    33901 aaccctatgg agtggcttct attcctagtg tcaatcactc taataccatt gccaatttta
    33961 tcaagggtta ctatgtcaag caaaattatg aaaatcagca ggttcacatt gttaccagac
    34021 tagataggga cacttctggc ttgatgctct ttgccaagca cggttatgcc catgcacgat
    34081 tagacaagca gttgcagaag aaatctatcg agaaacgcta ctttgctttg gttaagggag
    34141 atggacattt ggagccagaa ggggaaatta ttgctccgat tgcgcgtgat gaagattcca
    34201 ttattaccag acgagtggct aaaggcggaa agtatgccca tacttcatac aagattgtag
    34261 cttcttatgg aaatattcac ttggtctata ttcacctgca cactggtcga acccatcaaa
    34321 tccgagtcca tttttctcat atcggttttc ctttgctggg agatgatttg tatggtggta
    34381 gtctggaaga tggtattcaa cgtcaggctc tgcattgcca ttacctatcc ttttatcatc
    34441 catttttaga gcaagacttg cagttagaaa gtcccttgcc ggatgatttc agtaacctta
    34501 ttacccagtt atcaactaat actctataaa aactgtctca gagtataatt attatcttaa
    34561 aggagaaaac tcatggaagt ttttgaaagt ctcaaagcca accttgttgg taaaaatgct
    34621 cgtatcgttc tccctgaagg ggaagagcct cgtattcttc aagcaacaaa acgcttagta
    34681 aaagaaacag aagtgattcc tgttttgctt ggaaatcctg aaaaaattaa aatttatctt
    34741 gaaattgaag gaatcatgga tggttatgag gtcatcgacc ctcaacatta tcctcaattt
    34801 gaagaaatgg tttctgcctt ggtggagcgt cgcaagggca aaatgactga agaagatgta
    34861 cgcaaggttt tggttgaaga tgtcaactac tttggtgtga tgttggttta cttgggcttg
    34921 gttgatggaa tggtgtcagg agcgattcac tcaacagctt caacagttcg tccagctcta
    34981 caaatcatca aaactcgtcc aaatgtaact cgtacttcag gagccttcct catggttcgt
    35041 ggtacggaac gttacctatt tggagactgt gccattaaca tcaatccaga tgcagaagcc
    35101 ttggctgaaa ttgccatcaa ctcagcaatc acagctaaga tgtttggcat cgaacctaaa
    35161 attgccatgt tgagctattc tactaaaggt tcagggtttg gtgaaagcgt tgataaggtc
    35221 gttgaagcaa ctaaaattgc tcacgacttg cgtcctgacc ttgaaatcga tggtgagttg
    35281 caatttgatg cagcctttgt tcctgaaact gcagctctga aagctcctgg aagtacggta
    35341 gctggtcaag caaatgtctt catcttccca ggtatcgagg caggaaatat cggttacaag
    35401 atggctgaac gcctaggtgg ctttgcggct gtaggacctg ttttgcaagg tttaaacaag
    35461 ccagttaatg atctttctcg tggatgtaat gcagatgatg tttacaagtt gaccctcatc
    35521 acagcagctc aagcagttca tcaatagtga aaactataaa gcgatatact atgctatact
    35581 gtagttatga aactatgtac gaaaagcact gccattaatt cctgagaact aaattactga
    35641 ttggtgtcaa aaaggaaaac ttccaagcga taatatcctg tctatacacg acctatagaa
    35701 atctgtaata tacatgtccg taaaacgata aattcccttt ttgattttaa atgagtatga
    35761 aaagagaatt ttttggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
    35821 aggacaaatt ttgtcctttc ttttttgata ttcagagcga taaaaatccg ttttttgaag
    35881 ttttcaaagt ttcgaaaacc aaaggcattg cgtttgataa gtttgatgag attattggtc
    35941 gcttccaatt tggcgtttga atagggtagt tgaagggcgt tgacgatttt ctctttgtcc
    36001 tttagaaagg ttttaaagac agtctgaaaa agaggatgaa cctgctttag attgtcctca
    36061 ataagcccga aaaatttctc agggtctttg ttctgaaagt gaaacagcaa gagttgatag
    36121 agctgatagt gatgtttcaa gtcttgtgaa tagctcaaaa gcttgtcaag aatttcttta
    36181 tttgttaagt gcatgcgaaa agtagggcga taaaaacgtt tatcgctca
//
LOCUS       DAVKUR010000015        35932 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKUR010000015 DAVKUR010000000
VERSION     DAVKUR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.015"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            64..561
                     /locus_tag="VW749_000871"
     CDS             64..561
                     /locus_tag="VW749_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0174930.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            561..2216
                     /gene="dnaX"
                     /locus_tag="VW749_000872"
     CDS             561..2216
                     /gene="dnaX"
                     /locus_tag="VW749_000872"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0174931.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATDKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2244..2438
                     /locus_tag="VW749_000873"
     CDS             2244..2438
                     /locus_tag="VW749_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0174932.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2588..3358
                     /gene="sufC"
                     /locus_tag="VW749_000874"
     CDS             2588..3358
                     /gene="sufC"
                     /locus_tag="VW749_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0174933.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3386..4648
                     /gene="sufD"
                     /locus_tag="VW749_000875"
     CDS             3386..4648
                     /gene="sufD"
                     /locus_tag="VW749_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0174934.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4659..5885
                     /locus_tag="VW749_000876"
     CDS             4659..5885
                     /locus_tag="VW749_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0174935.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATAFYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5872..6312
                     /locus_tag="VW749_000877"
     CDS             5872..6312
                     /locus_tag="VW749_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0174936.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6366..7778
                     /gene="sufB"
                     /locus_tag="VW749_000878"
     CDS             6366..7778
                     /gene="sufB"
                     /locus_tag="VW749_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0174937.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8009..9250)
                     /locus_tag="VW749_000879"
     CDS             complement(8009..9250)
                     /locus_tag="VW749_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0174938.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9353..10462
                     /locus_tag="VW749_000880"
     CDS             9353..10462
                     /locus_tag="VW749_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0174939.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            10996..11343
                     /gene="ssrA"
                     /locus_tag="VW749_000881"
     tmRNA           10996..11343
                     /gene="ssrA"
                     /locus_tag="VW749_000881"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11516..11603)
                     /locus_tag="VW749_000882"
     tRNA            complement(11516..11603)
                     /locus_tag="VW749_000882"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11567..11569),aa:Ser,seq:gga)
     gene            11766..12506
                     /locus_tag="VW749_000883"
     CDS             11766..12506
                     /locus_tag="VW749_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0174940.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12503..13414
                     /gene="pfkB"
                     /locus_tag="VW749_000884"
     CDS             12503..13414
                     /gene="pfkB"
                     /locus_tag="VW749_000884"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0174941.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13411..15363
                     /locus_tag="VW749_000885"
     CDS             13411..15363
                     /locus_tag="VW749_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0174942.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15527..17752
                     /locus_tag="VW749_000886"
     CDS             15527..17752
                     /locus_tag="VW749_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0174943.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKPLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17797..18225)
                     /locus_tag="VW749_000887"
     CDS             complement(17797..18225)
                     /locus_tag="VW749_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174944.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18363..19505
                     /locus_tag="VW749_000888"
     CDS             18363..19505
                     /locus_tag="VW749_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0174945.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19514..20728
                     /gene="thiI"
                     /locus_tag="VW749_000889"
     CDS             19514..20728
                     /gene="thiI"
                     /locus_tag="VW749_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0174946.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20863..21686
                     /locus_tag="VW749_000890"
                     /pseudo
     CDS             20863..21686
                     /locus_tag="VW749_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            21708..22447
                     /locus_tag="VW749_000891"
                     /pseudo
     CDS             21708..22447
                     /locus_tag="VW749_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22460..23626
                     /locus_tag="VW749_000892"
     CDS             22460..23626
                     /locus_tag="VW749_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0174947.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            24134..25627
                     /locus_tag="VW749_000893"
     CDS             24134..25627
                     /locus_tag="VW749_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0174948.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25640..26704
                     /locus_tag="VW749_000894"
     CDS             25640..26704
                     /locus_tag="VW749_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0174949.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAY
                     GGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLV
                     FLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQLAI
                     QKSLEELETLKKSLMQEYFG"
     gene            26764..27000
                     /locus_tag="VW749_000895"
     CDS             26764..27000
                     /locus_tag="VW749_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0174950.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            26997..27410
                     /locus_tag="VW749_000896"
     CDS             26997..27410
                     /locus_tag="VW749_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0174951.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27528..28493
                     /locus_tag="VW749_000897"
     CDS             27528..28493
                     /locus_tag="VW749_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0174952.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLVSTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            28517..29100
                     /locus_tag="VW749_000898"
                     /pseudo
     CDS             28517..29100
                     /locus_tag="VW749_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            29130..32480
                     /locus_tag="VW749_000899"
     CDS             29130..32480
                     /locus_tag="VW749_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0174953.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFGENCCVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            32751..32828
                     /locus_tag="VW749_000900"
                     /pseudo
     CDS             32751..32828
                     /locus_tag="VW749_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(33066..33536)
                     /locus_tag="VW749_000901"
     CDS             complement(33066..33536)
                     /locus_tag="VW749_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0174954.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(33553..35826)
                     /locus_tag="VW749_000902"
     CDS             complement(33553..35826)
                     /locus_tag="VW749_000902"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0174955.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        10968 a         6425 c         7796 g        10743 t
ORIGIN      
        1 cctttgttta ctaaacaagg gatttttctt ttgtctctgc tccttttttg atataatagt
       61 tctatgttaa aatcagaaaa acaatcacgt tatcaaatgt taaatgaaga attgtccttc
      121 ctattggaag gcgaaaccaa tgttttggct aatctttcca acgccagtgc tctcataaaa
      181 tcacgttttc ctaataccgt atttgcaggc ttttatttgt tcgatggaaa ggaattggtt
      241 ttaggcccct tccaaggagg tgtttcctgc atccgtattg cactaggcaa gggtgtttgt
      301 ggtgaggcag ctcactttca ggaaactgtt attgttggag atgtgacgac ctatctcaac
      361 tatatttctt gtgatagtct agctaaaagt gaaattgtgg tgccgatgat gaagaatggt
      421 cagttacttg gagttctgga tctggattct tcagagattg aggattacga tgctatggat
      481 cgagattatt tggaacaatt tgtcgctatt ttgcttgaaa agacaacatg ggactttacg
      541 atgtttgagg aaaaatctta atgtatcaag cactttatcg aaaatataga agtcaaaact
      601 tctcccagtt agttggtcaa gaagttgtgg ctaagactct taaacaagcg gtggagcaag
      661 agaaaataag tcacgcttat cttttttctg gtcctcgtgg aacgggaaaa accagtgttg
      721 ctaaaatctt tgccaaggct atgaactgtc ccaatcaagt gggtggcgaa ccttgcaata
      781 actgctatat ttgtcaagca gtgacggacg gtagtttaga agatgtcatt gaaatggatg
      841 cagcttctaa taatggggta gatgaaattc gcgaaattcg tgataaatct acctatgcgc
      901 ctagccttgc tcgttataag gtttatatca tagatgaggt tcacatgctg tctacagggg
      961 cttttaatgc cctcctaaag acgctggaag aaccaacaca gaatgtagtc tttattttgg
     1021 ccactactga attgcacaag attcctgcta ctattctatc ccgtgtgcaa cgttttgagt
     1081 ttaaatcaat taagacacag gatattaagg aacatattca ctatatctta gaaaaagaaa
     1141 atatcagttc tgaaccagag gctgtggaaa tcattgccag acgggcggaa ggtggaatgc
     1201 gggacgcctt gtctattttg gatcaagccc tgagtttgac acagggaaat gagctgacga
     1261 ctgctatctc tgaagaaatt actggcacca ttagcctatc agccttggat gattatgtgg
     1321 cggccttgtc tcaacaggat gttcccaaag ctttgtcttg cttgaatctt ctttttgaca
     1381 atggtaagag catgactcgt tttgtgaccg atcttttgca ctatttaaga gacttgttaa
     1441 ttgttcaaac agggggagaa aatactcatc atagttcagt ctttgtagaa aatttggcac
     1501 ttcctcaaaa aaatctgttt gaaatgattc gcttagcaac agtgagttta gcagatatta
     1561 agtctagttt gcagcccaag atttatgctg aaatgatgac cgtccgtttg gcggaaatca
     1621 agcccgaacc agctctatca ggagcggttg aaaatgaaat tgctacgctg agacaggaag
     1681 ttgcccgtct caaacaagag ctttctaatg taggtgcggt tcctaaacaa gttgcaccag
     1741 ctcctagtcg accagctacg gacaaaacag tctatcgtgt cgatcgcaat aaagtgcaat
     1801 ctatcttaca agaggccgtc gaaaatcctg atttagcacg tcaaaatcta attcgtttgc
     1861 agaatgcctg gggagaggta attgaaagtc taggtgggcc ggacaaggct ctgctagttg
     1921 gttctcaacc ggttgctgcc aatgaacacc atgctattct tgcttttgag tctaacttca
     1981 atgctggtca aactatgaaa cgagacaatc tcaataccat gtttggtaat atcctcagtc
     2041 aggcggcagg tttttcacct gagattttag ctatttccat ggaggaatgg aaagaagttc
     2101 gcgcagcctt ttcagccaaa gccaaatctt ctcaaactga aaaagaagta gaagaaagcc
     2161 tgattccaga aggatttgaa tttttggctg ataaagtgaa ggtagaggaa gactaaagaa
     2221 agatttcatg atacaataag tttatgaata aacaacaatt tattattatg gcgctgttta
     2281 cagctgctga gacctatttt ttcaatgaag cctggatgac tggccgctat attatggcag
     2341 ccttttgggc aattttactc tttagaaatt tccgagtcag ttatgtgatg ggcaaaatcg
     2401 ttgatgtcat cgatcagcat tttaatagga aagactagcc ctcagcttcc agacaaaatc
     2461 aaagcctttt aggctttttt ttgttatact agaaaagtat atttatagaa tttttgctct
     2521 atttctgggg aaatcagacg tttttctagt aagtactgta aaagttttga aaaagaaagg
     2581 aactatcatg tcagtattag agattaaaga tcttcacgtt gagattgaag gaaaagaaat
     2641 tttaaaaggg gttaacctga ccctgaaaac aggagaaatt gccgctatca tgggaccaaa
     2701 tggtacaggt aaatcgactc tttctgccgc tatcatggga aatccaaact atgaagtaac
     2761 taaaggtgaa gttttgtttg atggcgtaaa catccttgag ttggaagtgg atgagcgtgc
     2821 gcgtatggga cttttccttg ctatgcaata cccatcagaa atccctggaa ttaccaatgc
     2881 tgagtttctt cgtgccgcta tgaatgcggg taaagaagat gatgagaaga tttcagttcg
     2941 tgagtttatt actaagctag atgaaaaaat ggaattgctc aacatgaaag aagaaatggc
     3001 agagcgttac ctcaacgaag gcttctctgg tggtgagaaa aaacgcaatg aaattcttca
     3061 acttttgatg ttggagccaa catttgctct tttggacgag attgactcag gtcttgatat
     3121 tgacgctctt aaagttgtgt ctaaaggtgt caatgccatg cgtggtgaag gttttggtgc
     3181 tatgatcatc actcactacc aacgtctttt gaactatatc acacctgatg tggtacacgt
     3241 gatgatggaa ggtcgtgttg tcctttctgg tggtccagaa ttggctgcgc gtttggaacg
     3301 tgaaggatac gcaaaattag ctgaagaact tggctacgac tacaaggaag aattgtaatt
     3361 tcctcgtatc ttttaggaga agtaaatgac tagagaaaat attaaacttt tttcagaaat
     3421 gcacgctgaa ccaagctggt tggctgatct ccgtcaaaaa gcttttgaca agattgagac
     3481 tttggaatta ccagttattg agcgtgtcaa attccaccgt tggaatctgg gtgatggaac
     3541 gattacagaa aatgagccat cagcaaatgt tccagatttc acagctttag atcatcactt
     3601 gaagttggtg caagtaggaa ctcaaactgt tttcgaacaa actccagttg agttagctga
     3661 acagggtgtt gtcttcacag actttcactc agctttagaa gaaattccag agctgatcga
     3721 agaattcttc atgtcatctg ttaagtatga tgatgacaag ttggcggctt accacacagc
     3781 ttactttaac agtggtgctg tactctatat tccagataac gtagaaatca cagagccaat
     3841 tgaaggaatt ttctaccaag atagcgatag caatgtgccg tttaacaagc atattatgat
     3901 tatcgctggt aaaaattcta agattagtta tctggagcgt ttagagtcac gcggtgaagg
     3961 aagtgacaaa gtaactgcca atatcacagt ggaagtgatt gcacgttctg gtgcgcaagt
     4021 caagtttgct gctatcgacc gtctaggtga aaacgtcact gcctacatta gccgtcgtgg
     4081 taaattaggc aacgatgcaa gtattgactg ggctatcggt gtcatgaacg aaggaaatgt
     4141 cgttgctgat tttgatagtg acttgattgg taatggtagc catgctgacc tcaaggttgt
     4201 agctctttca agtggtcgtc aggtacaagg gattgatact cgtgtaacta actatggctg
     4261 caactctatc ggaaatatcc tacaacatgg ggttatcctt gaaaaagcaa ctttgacttt
     4321 caatggtatc ggccacatca tcaagggtgc taagggagca gatgcgcaac aagagagccg
     4381 tgttctcatg ctttcagacc aagcgcgttc agatgctaac ccaattcttt tgattgatga
     4441 aaatgatgtc actgcaggac acgcagcgtc tatcggacaa gttgatccag aagacatgta
     4501 ttacctcatg agtcgtggat tggataaggc aactgcagag cgtttggttg ttcgtggttt
     4561 ccttggatct gttatcgtgg agattccagt caaggaagtt cgtgatgaaa tgattgcaac
     4621 tatcgaagag aaattgtcaa aacgctaagg ggaagcctat gttagatgta gaagcgattc
     4681 gcaaggattt tccaatttta gatcagattg tcaatgatga acctctggtc tatctggaca
     4741 atgctgcgac gacacaaaaa cccctagtag ttctgaaagc tattaacagt tactatgagc
     4801 aggacaatgc caatgttcac cgtggtgtcc ataccttagc ggaacgagcg acagcttttt
     4861 atgaagctgc tcgtgaaacc attcgtaagt ttattaatgc aggctctaca aaggaagttc
     4921 tctttaccag aggaacgaca accagcctta actgggtggc acgctttgct gaggaaattc
     4981 tcactgaggg agaccaggtc ttgatttcag taatggaaca ccattctaat atcattccat
     5041 ggcaggaagc ttgtcgaaag actggagcag agcttgtcta tgtctatctt aaagacggtg
     5101 ccttggatat ggaggatttg cgagctaaat tgactgataa ggttaaattt gtttccctag
     5161 ctcatgcctc caatgttctt ggtgtgatca atccgatcaa ggaaatcact caattagccc
     5221 accaagttgg ggcaatcatg gtagtggatg gtgctcaatc tacacctcat atgaagattg
     5281 atgtccagga cttggatctg gactttttcg ccttttcggg tcacaagatg gctggtccga
     5341 ctggtatcgg tgtcctttac ggcaaagaaa agtatcttga gcaaatgtct ccagtagaat
     5401 ttggcggcga gatgattgat tttgtctacg agcaatttgc tagttggaag gaattgcctt
     5461 ggaaatttga ggctggaacg ccaaatatgg caggagctat tggacttgcg actgcagttg
     5521 attatttgga aaagattggt atggatgccg ttgaagctca tgaacaggaa ttgattgcgt
     5581 acgtctatcc aaaactgcag gcaattgagg gattgaccat ttacggttct caggatttgg
     5641 ctcaacgttc gggtgttatt gcctttaacc taggtgatct ccatcctcac gatcttgcga
     5701 cggctctgga ttatgaagga gtggctgttc gtgctggtca ccattgtgcg caacccttgc
     5761 ttcagtattt ggaagtccca gcaacagctc gtgcaagttt ttatatctac aataccaagg
     5821 cagattgcga caaactagtc gatgccctac aaaagacaaa ggagtttttc aatggcactt
     5881 tctaaactag atagccttta tatggcagtg gtagcagacc attcgaaaaa tccacatcac
     5941 caagggaagt tagaagatgc tgagcaaatc agtctcaaca atccgacttg tggggatgtc
     6001 atcaacctct ctgtcaagtt tgatgcagag gaccgtttgg aagatattgc ttttctaaat
     6061 tcaggatgca cgatttcaac tgcttctgct agtatgatga cagatgccgt tttaggaaaa
     6121 accaaacaag aaattttaga actggcgact attttttctg aaatggttca agggcaaaaa
     6181 gatgagcgtc aaggccaact tggagacgcg gcattcttgt caggtgttgc caaattccct
     6241 caaagaatca agtgtgcaac cctagcttgg aatgccctta agaaaacaat tgaaaatcaa
     6301 gaaaaacagt aagacaagtt tcttttgtct tatgaattat tagaaatgaa gaaagaaagg
     6361 atactatggc tgaagaaaga gtagaaccaa aaccaattga ccttggtgaa tataaatttg
     6421 gtttccatga cgatgtagag cctgtcttat cgacaggaaa aggactcaac gaaggtgtta
     6481 ttcgtgaatt atctgctgct aagggtgagc ctgagtggat gttggagttc cgtttgaagt
     6541 cttatgaaac cttcaaaaaa atgcccatgc aaacttgggg agcagacttg tcagagattg
     6601 actttgatga cttaatctac taccaaaaac catctgacaa accagcccgt tcttgggatg
     6661 atgtacctga aaagattaaa gaaacctttg aacgtatcgg gattccagaa gctgaacgtg
     6721 cttatttagc aggggcttct gcccagtacg agtcagaagt ggtttaccac aacatgaagg
     6781 aagagttcca aaaattaggt attatcttta cagatacaga ttccgcactc aaggaatacc
     6841 cagacttatt taaacaatac tttgcgaagt tggtaccgcc gacagataac aagttggcag
     6901 ccctcaactc agcagtatgg tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg
     6961 tagatattcc acttcaaact tatttccgta tcaataacga aaatataggt cagttcgaac
     7021 gtaccttgat tatcgttgat gagggagcaa gcgtccacta cgtagaagga tgtacagcac
     7081 caacatattc aagcaatagc ttacacgctg ccattgtaga aatttttgct ttggacggag
     7141 cttatatgcg ttatacaact atccaaaact ggtctgataa cgtctataac ttggtaacaa
     7201 agcgtgctaa ggctcaaaag gatgccactg ttgagtggat tgatggaaac ttgggtgcca
     7261 aaacgactat gaaatatcca tctgtttacc ttgatggaga aggagcgcgt ggtaccatgc
     7321 tctctatcgc ctttgctaat gcagggcaac accaagacac gggtgctaag atgattcaca
     7381 atgctccaca taccagctcg tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg
     7441 ttgactaccg tggacaagtc acctttaaca agaactctaa gaaatctgtt tcccacattg
     7501 aatgtgatac cattatcatg gatgacttgt cagcatcaga tactattcca tttaatgaaa
     7561 ttcacaactc gcaagtggct ttggaacacg aagccaaagt atctaagatt tcagaagagc
     7621 aattgtatta tctcatgagc cgtggattgt cagaatctga ggcaactgaa atgattgtca
     7681 tgggatttgt agaacccttt acaaaagaac ttccaatgga atacgcagtt gagctgaacc
     7741 gcttgattag ctatgaaatg gagggatcag ttggataaaa tttgatttta tactcttcga
     7801 aaatctcttc aaaccacgtc agcatcgcct taccgtatgt atggttactg acttcgtcag
     7861 tttcatctac aacctcaaaa cagtgttttg agcaagctgc ggctagcttc ctagtttgtt
     7921 ctttgatttt gagtattaga tttactcaaa atcaaggatt ttgaagatga acttgtatca
     7981 aaaaatcgcg gtttaaaatc gcgatttttt ataatttctc gttaacaaag cggacaaact
     8041 gattccacca aacttttaag aagaaggctt tttcaatttt cttgtctgct accatttcga
     8101 aactagggcg ctctgtggtg atgtaacctt gaccaatcaa gtccttgtct tcataagtca
     8161 aatggccaac cactgttcca gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga
     8221 attgaacaga ttgggaagat tgattcccaa cacgttcgat tagatagata tcctctggag
     8281 ccactgcagt tactgtatct tcttttccat cttgtacagg ggttttgcta tcttgatagg
     8341 catcgccttg ttgaacgatt ttgcgaagtg taaatgtaga agaaatataa tccattaggg
     8401 aagatgtagc tgtaaatcga gcgtaaggat tattgtcttg atgatctgca tttaaaacaa
     8461 ctgtgatgac tctcatgcct ttttcgacag tagtaccaac aaaagactct ccagccttat
     8521 ctgttgttcc tgtttttagc ccatcaaaac caccacggta agcaggcata ccttctaaca
     8581 tgtagttggt tgaagtgatt gtcatcccag caaaagtaga agaaggtttt ttggtgattt
     8641 ctaagacttg tgggtatttt ttgatgaggt tgcgagcaac gatagcgaca tcataagcac
     8701 taagcttatt ttcctcatct tttttagaac ctgggtaaat gttatcccct agagtttcat
     8761 tgttaagacc tgtcgtattg acaacagtgg catcctgaat tccccattcc aagagttttg
     8821 cccgcatcat atcgacgaaa tctttttctg agccagcaat tttctcagct agggcaatag
     8881 cggcgctgtt ggcactagat accagagttg cttcaagcaa ctcttcgaca gtataattac
     8941 gggcctccat aggaatatta ctggcttcag aatttgtcgt caattgataa ggataatcag
     9001 aaatatctac aggagtggag agggtaatac ttccgttttc caaagcttca tagaccagat
     9061 aaacagtaat caattttgtt atggaagcaa tttcgacagg ttgcgttgca tccttctcat
     9121 agagaatttt accagtattt gcctcaacag caatcgcatg tttagcggca atggtaaaat
     9181 cttgagcaac agcagtagaa gcacccccta aaagagagac agttaacaaa gttaaaaata
     9241 tttttttcat agtagtctta ttctatcata aagaaaaaaa atattcttgc tttaataatt
     9301 catctgttaa gctttttgaa aatatggtaa aataaagtga gggaggtaac tcatgtttcg
     9361 tagaaataaa ttattttttt ggaccacaga aattttactc ttaaccatca tcttttacct
     9421 atggagacag atgggatctt tgattaaccc ttttgttagc gtgcttaata caattatgat
     9481 tccattttta ttagggggct ttctttatta tttgacaaac cctattgtta ctttcttaaa
     9541 taaagtctgt aaactcaatc gtttgcttgg tattttaatt accttgtgta ctttggtctg
     9601 gggaatggtc ataggtgttg tctatctctt acctattttg attaatcagt tatctagttt
     9661 gattatatct agtcaaacta tttatagtcg agtacaagac ttaatcatag acttatctaa
     9721 ttatcctgcg ctccagaatt tggatgtaga agctacaatt cagcagttaa acttatccta
     9781 tgttgatatt cttcaaaata tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc
     9841 agctcttatc agtactgttt tgattttgat tatgactcca gtttttttgg tttatttctt
     9901 attagatgga cataaattct tgcccatgct tgaaagaacg attctaaaga gggatcgctt
     9961 gcatattgca ggcttattaa agaatttaaa tgcgacgatt gctcgctata ttagtggagt
    10021 ttcgattgac gcaatcatta taggttgttt ggcttatatt ggctatagta ttattggttt
    10081 aaaatatgct ttagtttttg ccattttttc tggtgtagcc aatttaattc cttatgtggg
    10141 gccaagtatt ggtttgattc ctatgatcat cgcaaatata ttcactgatc cccatagact
    10201 gctgattgca gtgatttata tgcttgttgt tcagcaggta gatggcaata tcttatatcc
    10261 tcgaatcgta ggaagtgtta tgaaggttca tccaatcacg attttagttt tacttttgtt
    10321 gtcaagcaat atctatggtg tagttggaat gattgtcgca gtgccaacct attctatctt
    10381 gaaagaaatt tctaagttct tatcccgttt gtatgaaaat cataaaataa tgaaagaacg
    10441 agaaagagaa ttagctaagt aaaagtcagg agaaccctga tttttcttta ctggaagtgg
    10501 cctttagatt agaagactga aaataagtta aagtcttaaa ctaattttca cagctaagaa
    10561 tagtagaagt taatctgata aaaatcgaaa aaaccagtgg aattctgtgt cagggtaagt
    10621 tccactggtt ttcatagtct attaaagttc gaatgaaacc tatttatagt agattgaaac
    10681 tagaatagta cacctctaat tctaaaacat tgttagaaat cgatttgact gtcctgatct
    10741 attcgtccta ttcttatttc attttactat attttggtgc aataagtgaa aagtagaccg
    10801 aataatataa ggattgattt tatagttttt aaactcaaat gaattgaaat aaagagagta
    10861 cgaaaattct catctgaaag tattttagaa taattctctt cgtgaatttc ttcaaaacag
    10921 atagcttcat cttaggtatg tgatttcttt ttgcattttt gagttagata aggtataatg
    10981 gttttattgt cttttggggt cgttacggat tcgacaggca ttatgaggca tattttgcga
    11041 ctcgtgtggc gacgtaaacg ctcagttaaa tataactgca aaaaataaca cttcttacgc
    11101 tctagctgcc taaaaaccag caggcgtgac ccgatttgga ttgctcgtgt tcaatgacag
    11161 gtcttattat tagcgagata cgattaagcc ttgtctagcg gtttgataag agattgatag
    11221 actcgcagtt tctagacttg agttatgtgt cgaggggctg ttaaaataat acataaccta
    11281 tggttgtaga caaatatgtt ggcaggtgtt tggacgtggg ttcgactccc accggctcca
    11341 ttattccttt gcattccttg gtaaaacgtt gttaaatcaa cgttttttat ttttatcttt
    11401 ggtattcctt tgcattcttt tgctaaaaag ggagtcacaa acagacccta ttttaaaaaa
    11461 aggatagaaa aaaggataca acatttgtcg catcctaaaa ataatctttt ttcgacggaa
    11521 gacatgggat tcgaacccac gcacgctatt acacgcctac cgcgtttcca acacggcctc
    11581 ttaagcctct tgagtaatct tccaatactt actcaaatag tctaccataa aggctcttat
    11641 cttgcaataa aaattctaga aataagaaaa aatgatagat tttgaaagaa aatgataaaa
    11701 aatgcttgac ttcgaaagaa agtatgatag aatgaatagt gtaaacgata acaggaggtg
    11761 attcagtgtt aaaaacagaa cgtaaacaac taattttaga ggagttaaat cagcatcatg
    11821 tagtttctct agaaaaatta gttagtttgc tagaaacgtc agaatcaacg gttcgaagag
    11881 acttggatga gttggaagcg gaaaacaagc ttcgtcgtgt gcatggtgga gcagaactcc
    11941 cccactcctt acaggaagaa gaaaccattc aagaaaaatc tgtcaaaaac cttcaagaaa
    12001 agaagttgct ggctcagaaa gcagcctctc tcattaaaga aaaagatgtc atctttatcg
    12061 atgctggaac aacaactgct tttttgattc atgaattggt caataagaat gttacagttg
    12121 tgaccaactc cattcaccat gccgctcagt tggttgaaaa gcagattcca actgtcatgg
    12181 ttggaggaaa cgtcaagacg gcgacagatg ctagtatcgg gggcgttgct cttaaccaga
    12241 ttaaccaatt gcactttgac cgtgccttta tcggaatgaa tggtgttgac gatggctatt
    12301 atacgactcc tgatatggag gagggagctg tgaaaagagc tattttggag aatgccaagc
    12361 agacctacgt cttggtggat tcgtcaaaaa ttggacaaac ttgctttgcc aaggtagcac
    12421 cactcaaacg cgctatcgtt atcactagtc aagggcatga gctcttgcag gttattaagg
    12481 agaaaacgga ggtaatagaa gtatgattta tacagtcaca ctcaatccat ccattgacta
    12541 tatcgttcgt ttggaccaag tcaaagttgg tagtgtcaat cgtatggaca gtgatgataa
    12601 gtttgctggt gggaaaggaa tcaatgtcag ccgtgtcttg aaacgtttga atataccaaa
    12661 tacagcgacg ggatttatcg gtggctttac tggtaaattt atcacagata ctctagcaga
    12721 ggaagaaatc gagacacgtt ttgtccaagt ggcagaagat actcgtatca atgttaaaat
    12781 caaagcagac caagaaacag aaatcaacgg aacgggtcca actgttgaac cggttcagct
    12841 agaagaattg aaagctattt tatctagtct gacagtagaa gatacagttg tctttgcagg
    12901 ttcaagtgct aaaaatctag gcaatgttat ctataaggat ttgatttcct tgacgcgcca
    12961 gactggtgcg caagtggtct gtgactttga aggacagacc ttaattgata gtttggacta
    13021 ccagcctctt cttgtaaaac caaacaatca tgaacttgga gcgatttttg gggttaaact
    13081 cgaaagttta gatgaaattg agaaatacgc tcgtgagtta ctggctaagg gtgctcaaaa
    13141 tgttattatc tctatggctg gtgatggcgc ccttcttgtc acatctgagg gagcttactt
    13201 cgctaaacca atcaaaggaa cagtcaaaaa ttcagttgga gctggtgatt ctatggttgc
    13261 tggattcaca ggtgaatttg tcaaatcaaa agacgcagta gaagccttca aatggggagt
    13321 ggcttgcgga acggcaacta ccttctcaga tgacttggca acggcggaat ttattaaaga
    13381 aacatatgga aaagttgagg tagaaaaaag atgaaaattc aagacctatt gagaaaagat
    13441 gtcatgttgc tagatttgca ggcaactgaa aaaacagctg tcatcgacga gatgattaaa
    13501 aatttgacag agcacggtta tgtaacagat tttgaaacat ttaaagaagg aattttggcg
    13561 cgtgaagctt tgacttctac tggtttgggt gatggaatcg caatgcctca cagcaaaaac
    13621 gctgctgtca aagaagcgac agttctattt gctaagtcaa acaagggtgt tgactacgag
    13681 agcttggatg gacaagcaac tgacctcttc ttcatgattg cagctccaga aggtgccaat
    13741 gatactcact tggcagcctt ggcagaattg tctcaatact tgatgaaaga cggttttgca
    13801 gacaaacttc gtcaagcaac atctgcaggc caagttatcg aactttttga ccaagcttca
    13861 gaaaaaactg aggaacttgt tcaagcacct gctaatgact ctggtgactt tatcgtagct
    13921 gttacagctt gtacaacagg tattgcccac acttacatgg cccaagaagc ccttcaaaaa
    13981 gtagctgctg aaatgggggt tggtatcaag gtcgaaacca acggtgctag cggtgttgga
    14041 aatcaactaa ctgcagaaga tatccgtaag gctaaagcta ttatcattgc agcagacaag
    14101 gccgttgaaa tggatcgatt tgatggaaaa ccattgatca atcgtccagt tgctgacggt
    14161 atccgtaaga cagaagagct aattaacttg gctctttcag gagatactga agtctaccgt
    14221 gccgctaatg gtgccaaagc tgcaacagcc tctaacgaaa aacaaagcct tggtggtgcc
    14281 ttgtacaaac acttgatgag tggtgtatct caaatgttac cattcgttat cggtggtggt
    14341 atcatgattg cccttgcctt cttgattgac ggtgctttgg gtgttccaaa tgaaaacctt
    14401 ggcaatcttg gttcttacca tgagttagct tctatgttta tgaaaattgg tggagctgcc
    14461 tttggtttga tgcttccagt ctttgcgggt tatgttgcct actctattgc tgaaaaaccg
    14521 ggtttggtag caggtttcgt ggctggtgct attgccaaag aaggttttgc ctttggtaaa
    14581 attccttatg ccgcaggtgg tgaagcaact tcaactcttg caggtgtctc atctggtttc
    14641 ctaggtgccc ttgttggtgg atttatcgca ggtgccttgg ttcttgccat caagaaatac
    14701 gttaaagttc ctcgttcact cgaaggtgct aaatcaatcc ttctattgcc acttcttgga
    14761 acaatcttga caggatttgt tatgctagct gtgaatatcc caatggctgc aatcaacact
    14821 gctatgaatg acttcctagg cggtcttgga ggaggttcag ctgtccttct tggtatcgtc
    14881 cttggtggaa tgatggctgt tgacatgggt ggaccagtta ataaagcagc ttatgtcttt
    14941 ggtacaggta cgcttgcagc aactgtttct tcaggtggtt ctgtagccat ggcagcagtt
    15001 atggctggag gaatggtgcc accacttgca atctttgtcg caactcttct tttcaaagat
    15061 aaatttacta aggaagaacg taactctggt ttgacaaaca tcatcatggg cttgtcattt
    15121 atcactgagg gagcgattcc atttggtgcc gctgacccag ctcgtgcgat tccaagcttc
    15181 atccttggtt cagcagtagc aggtggactc gttggtctta ctggtatcaa actcatggcg
    15241 ccacacggag gaatcttcgt tatcgccctt acttcaaatg ctctccttta cctcgtttct
    15301 gtcttggtag gagcaatcgt aagtggtgtg gtttatggtt acctacgcaa accacaagca
    15361 taaaaaatag aaaaatgaaa agattggacc gtttggtgca gtctttttct cttcccgaaa
    15421 tgcctgtgaa atatggtata atagaagaat ggcaaacaag aatacaagta caacaagacg
    15481 gagaccgtct aaagcagaac tggaaagaaa agaagcgatt caacgaatgt tgatttcgtt
    15541 aggaattgcg attttattga ttttcgcagc cttcaaatta ggggctgcag gtataaccct
    15601 ttataattta attcgcttgc tagtgggtag cctagcttat ctggcgatat tcggcctatt
    15661 aatctatctc ttctttttca agtggatacg aaaacaggaa ggactcttat ctggcttttt
    15721 caccatattt gctggcttac tcttgatttt tgaggcctac ttggtttgga aatatggttt
    15781 ggacaagtcc gttctaaaag ggaccatggc tcaggttgtg acagatctga ctggttttcg
    15841 aacgactagc tttgctggag ggggcttgat cggggtcgct ctttatattc caacagcctt
    15901 tctcttttca aatatcggaa cttactttat tggttctatc ttgattttag tgggttctct
    15961 cctagtcagc ccttggtctg tttacgatat tgctgaattt ttcagtagag gctttgccaa
    16021 atggtgggaa gggcacgagc gtcgaaaaga ggaacgcttt gtcaaacaag aagaaaaagc
    16081 tcgccaaaag gctgagaaag aggctagatt agaacaagaa gagactgaaa aacccttact
    16141 cgatttgcct cctgttgata tggaaacggg tgaaattctg acagaggaag ctgttcaaaa
    16201 tcttccacct attccagaag aaaagtgggt ggaaccagaa atcatcctgc ctcaagctga
    16261 acttaaattc cctgaacagg aagatgactc agatgacgaa gatgttcagg tcgatttttc
    16321 agccaaagaa gcccttgaat acaaacttcc aagcttacaa ctctttgcac cagataaacc
    16381 aaaagatcaa tctaaagaga agaaaattgt cagagaaaat atcaaaatct tagaagcaac
    16441 ctttgctagc tttggtatta aggtaacagt tgaacgggcc gaaattgggc catcagtgac
    16501 caagtatgaa gtcaagccgg ctgttggtgt aagggtcaac cgcatttcca atctatcaga
    16561 tgacctcgct ctagccttgg ctgccaaaga tgtccggatt gaagcaccaa tccctgggaa
    16621 atccctaatc ggaattgaag tgcccaactc cgatattgcc actgtatctt tccgagaact
    16681 atgggaacaa tcgcaaacga aagcagaaaa tttcttggaa attcctttag ggaaggctgt
    16741 taatggaacc gcaagagctt ttgacctttc taaaatgccc cacttgctag ttgcaggttc
    16801 aacgggttca gggaagtcag tagcagttaa cggcattatt gctagcattc tcatgaaggc
    16861 gagaccagat caagttaaat ttatgatggt cgatcccaag atggttgagt tatctgttta
    16921 caatgatatt ccccacctct tgattccagt cgtgaccaat ccacgtaaag ccagcaaggc
    16981 tctgcaaaag gttgtggatg aaatggaaaa ccgttatgaa ctctttgcca aggtgggagt
    17041 tcggaatatt gcaggtttta atgccaaggt agaagagttc aattcccagt ctgagtacaa
    17101 gcaaattccg ctaccattca ttgtcgtgat tgtggatgag ttggctgacc tcatgatggt
    17161 ggccagcaag gaagtggaag atgctatcat ccgtcttggg cagaaggcgc gtgctgcagg
    17221 tatccacatg attcttgcaa ctcagcgtcc atctgttgat gtcatctctg gtttgattaa
    17281 ggccaatgtt ccatctcgtg tagcatttgc ggtttcatca ggaacagact cccgtacgat
    17341 tttggatgaa aatggagcag aaaaacttct tggtcgagga gacatgctct ttaaaccgat
    17401 tgatgaaaat catccagttc gtctccaagg ctcctttatc tcggatgacg atgttgagcg
    17461 cattgtgaac ttcatcaagg ctcaggcaga tgcagactac gatgagagtt ttgatccagg
    17521 tgaggtttct gaaaatgaag gagaattttc ggatggagat gctggtggtg atccgctttt
    17581 tgaagaagct aagtctttgg ttatcgaaac acagaaagcc agtgcgtcta tgattcagcg
    17641 tcgtttatca gttggattta accgtgcgac ccgtctcatg gaagaactgg agatagcagg
    17701 tgtcatcggt ccagctgaag gtaccaaacc tcgaaaagtg ttacaacaat aaaaaaatag
    17761 cttctttccg agtttggagg gaagctattt tagtggctat tgattgcttt tattttctga
    17821 agttggcgca ttggactgtt tttcgttttc agtagcaggt ttacttgaag caggagtaga
    17881 agagtcctga gttgctgttt tctgatcttc ttttttctct tccttgacgc tagattttgg
    17941 tgtttcctct tgctgtgttt tttcttgact agtgttagtc tctttagttg gactggtgtt
    18001 ttccttaggg gattcctttt ggatttcttt gacaatggtt gtcgtctggc ttgtcgtagg
    18061 ttctttttta atatttttgt tattatccaa ggcgttcatg atcgtgatac ccgcggtaat
    18121 caagccaagg atactagcga ttgtagcaac ggttttttga aagactgtaa agcctttttt
    18181 gatgtgttct gtttttggtt ttgaagttct acgatagtta gacatacatt ctctcctttg
    18241 attatgattt attatactct gtttctttaa aaaaatctta aaaaaagaga aattgccctt
    18301 tcttgtcgca ggctccgttt catgatacaa tagaaggagt gattttagaa agcgtgagaa
    18361 acatgattta ctttgataat tcggcgacga ccaggcccta tccagaagcc cttgaaacct
    18421 atatgcaggt ggcttcaaaa attttaggaa atccatctag tctccatcgt ttgggagacc
    18481 aggcaacacg aattttagat gcttcccgtc aacagattgc agatttaatc ggtaagaaaa
    18541 gtgatgaaat cttctttaca tctggtggga cagaagggga taactggatc atcaagggag
    18601 tagcatttga aaaagcccag tttggcaagc acatcatcgt atcagccatt gaacatccag
    18661 cagttaagga atcagccctc tggttgaaag ctcaaggttt tgaagtggat tttgctccag
    18721 ttgataacaa aggatttgtg gatgttgagg cgctagaaga tttgataaga cctgatacga
    18781 ccctcgtttc catcatggca gttaacaatg aaattggctc tgttcagccc attgaggcta
    18841 tttcaaaact attggcagac aagccaacta tttccttcca cgttgatgcg gttcaggcgc
    18901 ttgccaagat tccgactgaa aagtatctga cagaacgagt ggatttcgcg actttctctg
    18961 gtcacaagtt ccacggaatc cgtggtgttg gttttatcta tatcaagtct ggcaagaaga
    19021 ttacgcctct tttaacaggt ggtggtcagg aacgtgatta ccgttcgaca actgaaaatg
    19081 tggcaggaat tgcagcgacc gctaaggctc tccgtttatc tatggaaaag ctagatatct
    19141 ttaggagcaa gactgggcag atgaaggcag tgattcgtca agcacttctg gactatccgg
    19201 atatatttgt cttttcagat gaggaagact tcgcccctca tattctgact tttggaatca
    19261 agggtgttcg tggtgaggtc attgttcacg cctttgaaga ctatgatatt ttcatctcaa
    19321 cgacctcggc ttgttcgtcc aaggctggga aaccagccgg aaccctgatt gctatgggag
    19381 tggacaagga taaggctcag tcagctgtgc gtcttagtct agaccttgaa aatgatatga
    19441 gtcaggtcga gcagttcttg accaagctaa aattaattta caatcaaact agaaaagtaa
    19501 gataggagca ttcatgcagt attcagaaat tatgattcgc tacggtgagc tgtcaaccaa
    19561 gggcaaaaat cgtatgcgtt tcatcaataa acttcgcaat aatatttcag acgttttgtc
    19621 tatctatccc caagttaagg taacagcaga tcgcgaccgt gcccacgctt acctcaatgg
    19681 agcagattac acagcagtag cagaatcgct caaacaagta tttggaattc aaaacttttc
    19741 ccctgtttat aaggttgaaa aatctgtaga agttctgaag tctgctgtcc aagagattat
    19801 gcaggacatc tacaaggaag gcatgacctt taaaatctct agcaagcgta gcgaccacac
    19861 ctttgaattg gacagtcgtg aactcaacca aacgcttgga agggctgtat tcgaagccat
    19921 tccaaacgta caagctcaaa tgaaaagtcc tgacatcaat cttcaggtgg agatacgtga
    19981 agaagcagcc tatctttctt atgaaaccgt tcgaggggca ggtggattac cagtgggaac
    20041 ttctggtaag ggcatgctca tgttgtcagg gggaatcgat tcccctgtag ctggctatct
    20101 agcgcttaaa cgaggggtag atatagaggc agttcacttt gccagcccac cttacacgag
    20161 tcctggtgct cttaaaaaag cccaagattt gacccgtaaa ttaaccaaat ttgggggaaa
    20221 tatccagttt atcgaagttc cttttacaga gattcaagag gaaatcaaag ccaaagcgcc
    20281 agaagcctac cttatgacct tgacgcgtcg ttttatgatg cgtattactg accgtattcg
    20341 tgaggtacga aatggtttag ttatcatcaa tggggaaagt ctaggtcaag tagccagcca
    20401 aacccttgaa agtatgaagg ctatcaatgc tgttaccaac actcccatca ttcgtcctgt
    20461 ggttaccatg gacaagttgg aaatcattga catcgcccag gaaatcgata cctttgacat
    20521 ttcaatccaa ccgtttgaag actgttgtac catttttgca ccagatcgtc caaaaacaaa
    20581 tcctaaaatt aagaatgcgg agcagtacga agcgcgtatg gatgttgaag gcttggttga
    20641 gcgagcagtg gctggaatca tgattactga aatcacacct caagccgaaa aagatgaagt
    20701 tgatgacttg attgacaatc tgctctaatt cagaaaatcc aaaagaatag cgaaaatcag
    20761 taaaaaaagt tagttttttc tctaaaaaca ggtaaaaaac taactttttt tatttttatg
    20821 atataatgat ataaaatttt gaatatagag agttttctgg caatgaatca atcctacttt
    20881 tatctaaaaa tgaaagaaca caaactcaag gttccttata caggtaagga gcgccgtgta
    20941 cgtattcttc ttcctaaaga ttatgagaaa gatacagacc gttcctatcc tgttgtatac
    21001 tttcatgacg ggcaaaatgt ttttaatagc aaagagtctt tcattggaca ttcatggaag
    21061 attatcccag ctatcaaacg aaatccggat atcagtcgca tgattgtcgt tgctattgac
    21121 aatgatggta tggggcggat gaatgagtat gcggcttgga agttccaaga atctcctatc
    21181 ccagagcagc agtttggtgg taagggtgtg gagtatgctg agtttgtcat ggaggtggtc
    21241 aagcctttta tcgatgagac ctatcgtaca aaagcagact gccagcatac ggctatgatt
    21301 ggttcctcac taggaggcaa tatacccagt ttatcggttt ggaataccaa gaccaaattg
    21361 gttgcttggg cgttttttca tctgcaaact ggctccacca agaagccttt aaccgctata
    21421 tcgagtgcca gaaactatcg cctgaccagc gcatcttcat ctatgtagga acagaagaag
    21481 cagatgatac agacaagacc ttgatggatg gcaatatcaa acaagcctat atcgactcgt
    21541 cgctttgcta ttaccatgat ttgatagcag ggggagtaca tctggataat cttgtgctaa
    21601 aagttcagtc tggtgccatc catagtgaaa tcccttggtc agaaaatcta ccagattgtc
    21661 tgagattttt tgcagaaaaa tggtaagtta agaaaggaaa aaacgaaatg catattgaac
    21721 atcttagcca ctggagtggt catcttaacc gtgaaatgta ccttaaccgt tatggacatg
    21781 gtgggattcc agttgtggtc tttgcttcat caggtggtag tcacaacgaa tactatgatt
    21841 ttggcatgat tgatgcctgt gcttccttta tcgaggaagg ccttgtccag ttctttaccc
    21901 tatctagttt ggatagtgag agctggttgg ttacttggaa aaatgctcat gaccaagcgg
    21961 aaatgcaccg tgcctacgaa tgttatgtga ttgaggaggc cattctttta tcaagcacaa
    22021 gacaggttgg tttgatggca tgatgacgac aggttgctct atgggagcct atcatgcact
    22081 caatttcttc ctccagcatc cagatgtctt taccaaagtg attgctctca gtggtgttta
    22141 cgacgcacgt ttctttgtcg gtgattacta caacgatgat gctatttacc aaaactcgcc
    22201 agtagattat atttggaacc aaaacgacgg ctggtttatt gaccgttacc gtcaggcaga
    22261 gattgtgctg tgtacggggc ttggagcctg ggaacaagat ggtttgccat ccttttacaa
    22321 gctcaaagaa gcctttgaca agaaacaaat tccagcctgg tttgctgaat ggggacatga
    22381 tgtcgcccat gactgggaat ggtggcgtaa acaaatgcct tatttcctcg gtaatctcta
    22441 tttataaaag gagttaccta tgaattacct tgttatttct ccctactatc cacaaaactt
    22501 tcaacagttt accatcgaac tagctaataa aggcatcaca gtcttgggaa ttggtcaaga
    22561 gtcttacgag caattggatg agcccttgcg caatagcttg accgagtatt ttcgtgttga
    22621 taatcttgag aacatagatg aagtcaaacg tgcagttgct tttctctttt ataaacatgg
    22681 tccaattgac cgcatcgagt ctcacaatga atactggctt gagctagacg caacactcag
    22741 agaacaattc aatgtttttg gtgccaaacc agaggatctc aaaaagacga aatataagtc
    22801 tgaaatgaag aaacttttca aaaaagcagg tgttcctgtg gtacctggag ctgttatcaa
    22861 gacggaagca gatgttgatc aagcagtgaa agaaatcggt cttccaatga ttgccaaacc
    22921 tgataatgga gtgggagcag ccacaacctt taaacttgag acagaagacg atatcaatca
    22981 cttcaagcaa gaatgggacc attcaaccct ttatttcttt gaaaaatttg tcacttccag
    23041 cgaaatctgt acctttgacg ggctcgtgga caaggatgga aagattgtct tctcaacaac
    23101 ctttgactac gcctatacac cgcttgacct catgatttat aagatggaca attcttatta
    23161 tgtgctcaag gatatggatc ctaaactgcg caagtatggg gaagcaattg tcaaagaatt
    23221 tggtatgaaa gaacggtttt tccatattga gttcttccgt gagggggacg attatattac
    23281 catcgagtac aataaccgcc ctgcaggtgg ttttaccatt gatgtttata actttgctca
    23341 ttccttggac ctctatcgtg gctatgcagc tattgtcgca ggagaggagt tcccggcgtc
    23401 agactttgaa actcagtatt gtttggctac ttctcgccgt gcaaatgctc actatgttta
    23461 ttcagaagag gatttgcttg ccaaatatag ccagcagttc aaagttaaaa aagtcatgcc
    23521 agctgccttc gcggaacttc aaggagatta cctgtatatg ctgaccactc cgagtcgaca
    23581 agaaatggag cagatgattg cagatttcgg acaacgtcaa gaataagaac tatcggatta
    23641 aggaaattaa ctcccttaat ccttttgttt tgtctgataa aaaataagag catcccaaca
    23701 aggtagctat cataaaactt gttcgataac tatttgaagc aggattaggt ggtcagaaat
    23761 tgaattttaa tatttcaatt gagtcatagt attgtgtttg cgtatcctta aatcagctaa
    23821 aaggatccat gacgacacct atacgatata gttttcaaga taccaaacaa gtctattaat
    23881 actcaatgaa aatcaaagag caaactagga agctagccgc aggtttctca aaacactgtt
    23941 ttgaggttgt ggatagaact gacagagtca gtatcatata cctacggcaa ggtgaagctg
    24001 acgtggtttg aagagatttt cgaagagtat aaaatattca ggtgacgcat agatatagtt
    24061 aattgaagct ttgtttgaaa tctgataaaa taatgatatt actaagtttt aaaaactaaa
    24121 gaaaagggaa gatatgatta caggcgaatt aaaaaataaa atcgatcagc tgtgggaaat
    24181 tctttggaca gaaggaaacg caaatccttt aacaaatatt gaacagttga cttatctctt
    24241 atttatgaaa gatttggata gtgtcgagct tggacgtgaa agtgatgctg aatttctagg
    24301 gattccttat gagggagttt ttccaaaaga taaacctgaa taccgttggt caacttttaa
    24361 aaatatagga gatgctcagg aagtttatcg tttaatgact caggagattt ttccgtttat
    24421 taaaaatctc aagggggata cagatgatac agccttttca cgatatatgc gagaagctat
    24481 ttttcaaata aataaacctg ctacgcttca aaaggcaatt tctatcttag atgtttttcc
    24541 aactagggga ttagatgtag attttgataa tgacaaacaa agtattactg atatcggaga
    24601 tatctatgaa tatctgttat caaaattgtc gaccgcaggt aaaaatggac agttccgtac
    24661 acctcgtcac atcatcgata tgatggttga gttgatgcaa ccgactatca aagatatcat
    24721 ctcagatccc gctatgggtt ctgctggctt cttagtatct gctagccgtt acttaaagcg
    24781 taagaaagat gaatgggaaa ccaatacaga taatatcaat cattttcata atcagatgtt
    24841 tcatggaaat gatacggata cgactatgtt gagacttggg gcgatgaaca tgatgctaca
    24901 tggagtagaa aatccacaaa tcagttacct tgactcgctg tctcaagata atgaagaagc
    24961 cgataaatat actttggttt tagcaaatcc tccttttaag ggctcacttg actacaattc
    25021 aacctctaat gaccttcttg caaccgtaaa aaccaaaaaa acagaattac tctttctttc
    25081 tcttttcttg cgaactttaa aaccaggtgg acgagcagca gttatcgtac ctgatggtgt
    25141 cctttttggt tcgtctaaag ctcataaagg aattcgtcag gaaattgtag agaatcataa
    25201 gcttgatgct gtaatctcaa tgcctagtgg tgtgttcaag ccttatgctg gagtttcaac
    25261 tgctattctc atctttacaa aaactggtaa tggtggtact gacaaagtct ggttttacga
    25321 tatgaaagcg gatggtttaa gtttggatga taagcgacaa ccgattagcg acaatgatat
    25381 tccagatatt atcgaacgct ttcatcatct tgaaaaagaa gcagaacgtc agagaacgga
    25441 tcaatctttc tttgttccag ttgctgagat aaaggaaaat gattatgatt tgtctatcaa
    25501 taaatataaa gagattgagt atgaaaaagt tgagtatgaa ccaacagagg tcatcttaaa
    25561 gaaaatcaat gatttagaaa aagaaattca agctggcttg gctgaattag aaaaattact
    25621 caagtaggga ggtggctgta tgaaaaaagt gaagttgggg gaagtcttat ctctaaaaaa
    25681 aggaaagaaa gccactgtac ttgctgaaca aacaactcta agccaacgtt atattcaaat
    25741 agatgattta agaaataata ataatttaaa attcactgaa agtttaaata tgactgaagc
    25801 actcccagat gatattctaa tagcatggga tggtgctaat gcaggaacag ttggctatgg
    25861 gttatcggga gctgttggta gtacaattac ggtcttaaaa aagaatgagc gatacaaaga
    25921 aaaaattata tcagattact tgggagtctt tttggaaagt aaatcgcagt atttacgaga
    25981 tcattcaaca ggtgcaacta ttcctcattt aaacaagaat atattacttg atttacaatt
    26041 agaattgcta ggtatcgaag aacaagagaa cattatctgt attcttaata cgattaaaag
    26101 gcttattact aaaagaaaat ttcagttaga tgaactaaac ttgctcgtca aatcccgatt
    26161 taacgagatg tttggggatc ctttaaataa taacaagaaa tttgcagtaa aaacgggaca
    26221 acagtgtttt aaattttcaa gtggaaaatt tcttgataaa catgatagag tttttgaagg
    26281 ttatcctgcc tatggtggaa atggcattgc ttggaaaagt cgaaaatatt taattgataa
    26341 tcctactatc atcattggtc gtgtaggtgc atattgtggt aatgtaagaa ctacccacgg
    26401 taaggtatgg ataagtgaca atgctatata tataaaagaa tttaagaatt ccgatttcaa
    26461 tcttgtattt ttattagaat taatgaaagt aattgatttt agtaaatttg ctgatttctc
    26521 aggtcaacca aagataactc aaaaaccatt agaaaatcag aaatatatcc tcccccctct
    26581 agccctccaa aatgagttcg cagactttgt agccctggtc gacaaatcac aattggcaat
    26641 ccaaaaatct ctggaagaac ttgaaacttt gaagaaatct ctgatgcagg agtattttgg
    26701 ctgatattct gccattgtaa ttacggtaat gatttgttat aatacttcaa aggaggaaat
    26761 cagatggtag taaaaacaag aaaacaagga aattcaatca ccattacgat tccaagtgaa
    26821 tttaatattc caagtggtgt taaatacgaa gcgaaattgt taccaagtgg tgagattatc
    26881 tttactcctg aagaattggg gcagcaggtt tcttatgtat ctgatgatgc ctttgactta
    26941 aatttagata aaatatttga cgaatacgac gatgttttca aagctttggt ggaaaaatga
    27001 caatctatct gacagaaaag caaattgaaa aaataaatgc tttagcaatt caacggtatt
    27061 ctccaaatga gaaaattcaa acagttagtt cttctgcctt aaatatgatt gtgaacttac
    27121 cagaacaatt tgtctttggg aagtctcttt atccaacaat ttttgataaa gcaacgatac
    27181 tatttgtcca attgataaag aagcatgttt ttgctaatgc taataaaaga actgctttct
    27241 tcgttttggt caaattttta caattaaacg gctatcgttt ttctgtaacg gtagaagaag
    27301 cagtaaaaat gtgtgtaacc atcgcagtag aagctttaac tgatgaaaaa atgacaagct
    27361 actccaaatg ggtttctgaa cattctgtta gagaaaaggt caaaaagtaa cctagtatgc
    27421 tggatttgaa tgagcacaag aaaataaatg aacagacaat attagaattc tgtaatgcag
    27481 aaactgatat tgtctctttt tattgatgaa taagaaagtg agaaattatg gaatcaaaag
    27541 ttacaattat catgcaagaa atgttacctc ttttaaataa tgaacaatta ctagcgttga
    27601 gagagagttt agaacatcat ctagtagacg gaaaaaagca gcagaagtat tcgaataata
    27661 acctgttgca actatttatt accgccaagc aggtagaggg ctgtagctca aaaacaattc
    27721 gttattacca gaggacgatt gaaaacttgt ttaatgctat taaagagtct gtgacacaac
    27781 tcacaacaga tgatttaagg agttatttag caaattacca gtctgaaaag gattgtagta
    27841 aggcaaattt agacaatatt aggcgtatat tgtcttcttt ttttgcttgg cttgagcaag
    27901 aggaatatat cattaaaaat cccattcgac ggataaagaa aattaagact gagcaaaatg
    27961 tgaaggaaac ttatactgat gaacatttgg aaattatgcg tgataactgt gaaaatttga
    28021 gagatttggc aataatagac ctactagtat cgacaggtat gcgtgtaggg gagcttgtac
    28081 agttgaatcg ttcagatatt gattttgaaa acagagagtg tgttgtcttt ggtaaaggaa
    28141 agaaggagag accagtatat tttgacgctc ggacgaaaat tcatttaaga aattatctta
    28201 acgacagaaa agatagtcac cctgctcttt ttgtaacgct agttggaaaa gcccagagac
    28261 ttggaattgc tggtgtagag attcgcttaa gaaagttagg agacaaactc ggcatacaaa
    28321 aggttcaccc acataagttc agaagaactt tagcgactaa ggcaattgat aaaggtatgc
    28381 ctatcgaaca agtccaaaaa ctgctaggtc atagcaagat tgacacaacc ttggcctatg
    28441 ccatggtcaa tcaaaataat gtcaagcatt cacaccaaaa attcatctct taaaagcaaa
    28501 ttcccgattt aacgagatgt ttggggaaaa taaaatattt gaaagcattg ataacttatt
    28561 tgatattata gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt tgtttagtga
    28621 ggagtactgt ttatttttaa atacaaagaa tgttactaaa aacggatttt cattcgatac
    28681 aaagcaattt atcactaaaa caaaggataa attacttcga aaaggcaaac ttgagcgtta
    28741 tgatatagtc ttgacaacaa gaggtactgt tggaaatgta gcgtactacg atgaattaat
    28801 aaaatataaa catttacgta taaattcagg tatggtaata ttacgtccca agacaccaaa
    28861 tctaaatcag aaatttatta tccatgtttt aaggaataat aattatagtc gagtgatatc
    28921 aggaagtgct cagcctcagt taccaattac aaaattaaaa aaaatacttc tccccctccc
    28981 cccactagcc ctccaaaatg agttcgcaga ctttgtagtc caggtcgaca aatcacaatt
    29041 tgcttgtgag atagctatat aaaagtgtgg agaaatagct tgaaatttag tataatatag
    29101 ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt ttaaaaaatg
    29161 acgaatatga atctttttca aaaccttgca ttgaagctga gaatatgatt gctacatcaa
    29221 ctgtggctac tgcctttatg gcgcgtcgtg ctttagagca ggctgtccat tggatatata
    29281 gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta gtatgggatg
    29341 atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg ttgattcggt
    29401 ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt ttagctttgc
    29461 atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgag tttgtggagc
    29521 gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga gaaactccac
    29581 aatctatgat aaagttacaa gacagtttac cagaactgcc tgattttcat gaacagatgg
    29641 ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact gcagcgcaac
    29701 ggcaagatgt gcctttccat attgatcaat tatctgaggc agagacaaga aagctcttta
    29761 ttgatatcga tctccgttta gcaggatgga tatttggaga aaactgttgt gttgagatag
    29821 ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactatgta ctttatggta
    29881 aaaatgggaa aattttagcg attgtggagg ctaaaaaagc ctctgtcaat ccagaagtag
    29941 gggaagtaca ggtcaaagaa tatgctgaag ctttggagaa acatatcggc tatcagccaa
    30001 tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac cgacgccaga
    30061 ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt catcttcaaa
    30121 aaccacttga ggatatttct agtaaaatta gggacgatat ttccgggcgt cactaccaaa
    30181 aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag gcacttttgg
    30241 ttatggcaac tggggcgggg aaaactcgta cagcagtttc tctagttgat atcttatcac
    30301 gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg gttaagcaag
    30361 cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc ttagaagata
    30421 aagaaggagc tcaatcaagt cgtatggtct tttcaactta tccgaccatg attggagcga
    30481 ttagtggtca agaagaagta aatcaacgcc cttttactgt tgggcatttt gaccttatca
    30541 taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt gattattttg
    30601 atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa aacacctatg
    30661 gattctttaa tttggagaat ggggttccaa catatgcata tgatttggaa gaggctgtta
    30721 aagacggata tttagtagcc tatcattcta tcgaaaccaa actgaaacta cctacggatg
    30781 gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc aaatttgaag
    30841 acgatagctg tgaaaaagat attgatggga gtgtatttaa ttcctttgtt ttcaataaaa
    30901 gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca gcctcgggtg
    30961 atgaaattgg taaaactatt atttttgcta aaaatcatga tcatgcagaa tatatcagag
    31021 gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg attgattata
    31081 gtattaagca ttatcagacc ttgattgatg attttaaaat tgaggagaag tatcctcaaa
    31141 ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt gttaatttag
    31201 tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt cgaggaaccc
    31261 gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg gtatttgatt
    31321 atggggataa ttttgattat tttcgtgcag atccaagaga tggagagggt cgtcacattg
    31381 tttcgttgac tcagcgttta tttaatatca aagtggactt gattcgagaa cttcagggac
    31441 tccaatacca agaagatcag tttgcgagag cataccgtca gcagcttgtc tcggaacttc
    31501 aaggtcgtat agagagctta aatgagttgg acttcagggt tcgtatggtt ttagatacag
    31561 tttatagcta taggaaattg gaaagttggc agaatctaac tgctgttaca agtgaaacca
    31621 ttcaaaaaaa tctctctccg cttttatttg atgaagataa agaagatgag atggccagga
    31681 gatttgattt gtggttgctt catattcagt tggggcaact gacagctaaa tcttccactg
    31741 ttcatatttc ccaagtgatg aagacggcta gagctctttc tgctattggc aatatcccgc
    31801 aggtttttga gcaggctgaa attatcagga aagtacagga gcctgaattt tggaaagaag
    31861 ttaacttgtc tgatttggaa aaaattcgtc ttgctattcg agatttatta cagtttttgg
    31921 ataaaacaga ccgtaaaccc tactatgtta actttgaaga tcgtatactc tccactgttc
    31981 acgagaccac agcatttttg caggtcaacg atcttcggtc ttacaatgaa aaagttgagc
    32041 attatttgaa aactcatctg gatgaggagt ccatttctaa gctataccat aataaaaagt
    32101 tgacatctga tgatatgctt gcacttgaaa aattgctttg ggaaaaatta ggtagtaaag
    32161 cagactacca aagtcattat gaaaataagg caattccgag attggttcgt gagattattg
    32221 gcttagatag agagtctgcc aatcgtattt tttctaaatt tttgtcggat gagaatctta
    32281 atgccaggca gatttcattt gtaaaattga ttgtagacta cattgtagaa aatggttttt
    32341 tagagacgaa agtgttaacg caagagccgt ttaaatctta tggttctgtt caactactct
    32401 tccaacacca actaccagta cttcgtaata ttgttcaaat cattgaactt atcaataatc
    32461 gagctggaga agcggcttaa attctaaagt gattgccatg ctgagactca tttaaaatta
    32521 aaaagagtag aaatttatgc tatatatgag aagttttatt aggaagaatg tcatcgtttt
    32581 cctagaatac agtatcagtt gttaagtggt tgataaattt caaagtagat acttgtacca
    32641 cgatgtttgt tgatcgagtt attaacaaaa gagctacttt gattttaaag aaatagaaaa
    32701 caaaaagccg agcaagaatt caattgcagg agaaaatgaa ataatactca atgaaaatca
    32761 aagagcaaac taggaaacta gctgcaggct gctcaaaaca ctgttttgag gttgcagata
    32821 agactgacga agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca
    32881 gtaaccatac ctacggcaag gcgacgttga cgcggattga agagattttc gaagagtata
    32941 aatcttccta ggataaagca aaacgcatag tatcaagggt tttcaacact tgatactatg
    33001 cgttttctga tgttaaagac tttctaccag tttttttaag cataattgtt agttgtagtc
    33061 atttattatt cttcaaagaa aaatggtggg gcgaattttt tcagttcttc aaagcacttt
    33121 tgagcagtat ctgcatcttc acagatgata agacagacat cattaccaca aagggtagcg
    33181 atagcgtcag ggaagctcaa agtatcaatg atagaaccaa aggattgagc cagtccagga
    33241 agggttttta gtaggacttg gtgttgaact gggcgcatcc agacaagggc gtcttccatg
    33301 tagagttcga gacgtttttc ccattttgag atggaaccat tgttaagaac ataataagcg
    33361 ctatcttctt cgcggacttt tgataggttc atatttttga tgtcgcgtga gagggttgcc
    33421 tgggttactt gaatgtcgtt cttagcaaga agggcttgca actcagcctg tgtatgaatc
    33481 ttgttttttg tgataagagc gcgtataagt tggtggcggt gttctgattt attcataata
    33541 atgtaactcc ttttagcaag gtaaggtaag catggactga gcgaggtcga cagtcaagtg
    33601 gtagtctgta ttgtcacgga tggtgatttc aaagtcagta gtatagagga ctaaacggag
    33661 agtgtctcct tcttttagct tgtaaatagt tggctgcagt tcaaattgaa catccatcca
    33721 ttcatctgca gtaatatcct ctactaacag taaatcattt ctattttgta aattaaggta
    33781 accttttgtc acgactcgtt gtgcctctgg tctaaatggc aattcacaga gattttccaa
    33841 catgtgatag cgaccgttgt caatggttct agcacttaaa atagctggat aaggttgtag
    33901 gtatttcttt tgcccaaatt ctagcagttg ggcagataag agccccttgt ttgtactgga
    33961 tttgatacga agattgagct gagcgcgacc gtttaggtgg agatctttag tcacaggaag
    34021 gttaatagta atctgattgg ctttcccttg atagagctct gtattgaagg tttggtatgt
    34081 cttaccatag cgctcaaaat ccttatctgg gtactggttt tgaatagctt gctcttcttg
    34141 accaagtgag aaggtttcac agttttcttg cccaccgaag ttatcaagtg ataaccaagt
    34201 ctgtggagct gtattgtcct gccagataac agtaggaagt tgaaagtctg tttcctgtcc
    34261 tagtaatttc ttggtcaata aggcatttat ggactcacgg aagtcaattg attgccaatt
    34321 gttcatgtaa acatgggcac cattatggaa aaagagatgc ttgtttatat gagtaggaag
    34381 agcatggaac atctggtaaa catgaagtgg tttgacattc caatcctgag aaccatgagt
    34441 aaagacaacc tctgccttta ctttatgggc attgagcaga taattgcggt catgccaaaa
    34501 ctgattgtag tccccagttt ttcggtctag ctgagctttc actttttcta agtcagcttg
    34561 gtgagcttca ttgccacgga tatagtcgcc agctaagaga ttacgagaat aggttaactc
    34621 agcaagggag tcaaagtcct cacctggata accacctggg ctagtcacca gaccgttttc
    34681 acggtagtag ttgtaccatg atgaaattcc tgcctcggca atgataactt ctaaaccatc
    34741 gactcctgta gtcgcaagac cattggacat ggtacctaga taggaaagtc ctgttgtagc
    34801 aacttttccg tttgaccaat cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc
    34861 acggcaacgg ccgttaagcc aatcgatgac atttttataa gcctcgattt gctggtagtc
    34921 tccattagtc atgaaacctg tcgagtcttt ggtaccaaca cctgagacat agagattggc
    34981 aaagcctctc ggaaggaagt agtcgtttag tgtatagcta gagttgatgt gagttagctt
    35041 ttcctcagcc tctgctataa gctcagcttt accttggggt tggacgagat ttagttgagg
    35101 tttctctagc tcaatcttgt gaggaagctt aacctcaagc tcgccctcca tcttgtagag
    35161 agccttgtca ctagccttgt cattggttcc ctgatgataa gggctggctg tcatgatggc
    35221 agggattttt ccatcaaaac gagggcgaat aatgctaacc tttactaggt ctgatagccc
    35281 tttttggtca gtatcgacac gagactcaac gtaaacgact tcacgaatga catcctggtt
    35341 agaaaaagta gccaaactct tgccgttaaa gtagtggtag tcattatcct ccggaataag
    35401 accatcacta acaagttggt cgataagagt atttcctttt ttggtgcgag tattgagtaa
    35461 ctgatagaga ttttcaatca agtcaccata tataatggga aatccagttt ctttacgaaa
    35521 aacgtcacta tcttcgaagt caaccaaata agaaaagcct aaaagttgaa aagcaacagt
    35581 ataaaaaata tctgctgtca gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt
    35641 tttatcagct gctaggatag aaagtgggta gttggtgtct tgataagtga aaaagaaacg
    35701 acgtaaaaag gtttcaagtg agtctttgtg attggctgta ttttgtaaat caaagccaca
    35761 tttttttagt tcagataaga cattttcttt tggaaaattg atataactat attgattaaa
    35821 acgcatagaa cctccatata gaatgacagt taaggttatt atatcaaaaa aaaagcagaa
    35881 agggaattgt taacttcaaa aggaaataat ccaataaaaa tgaataaagt ac
//
LOCUS       DAVKUR010000016        35290 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKUR010000016 DAVKUR010000000
VERSION     DAVKUR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.016"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(224..442)
                     /locus_tag="VW749_000903"
     CDS             complement(224..442)
                     /locus_tag="VW749_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0174956.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            594..674
                     /locus_tag="VW749_000904"
                     /pseudo
     CDS             594..674
                     /locus_tag="VW749_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(1081..1239)
                     /locus_tag="VW749_000905"
                     /pseudo
     CDS             complement(1081..1239)
                     /locus_tag="VW749_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1512..2201)
                     /gene="rplA"
                     /locus_tag="VW749_000906"
     CDS             complement(1512..2201)
                     /gene="rplA"
                     /locus_tag="VW749_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0174957.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2409..2834)
                     /gene="rplK"
                     /locus_tag="VW749_000907"
     CDS             complement(2409..2834)
                     /gene="rplK"
                     /locus_tag="VW749_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0174958.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2957..3103
                     /locus_tag="VW749_000908"
     CDS             2957..3103
                     /locus_tag="VW749_000908"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174959.1"
                     /translation="MYSMKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTD
                     AVSR"
     gene            complement(3143..3859)
                     /locus_tag="VW749_000909"
     CDS             complement(3143..3859)
                     /locus_tag="VW749_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0174960.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3862..4332)
                     /locus_tag="VW749_000910"
     CDS             complement(3862..4332)
                     /locus_tag="VW749_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0174961.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4334..5371)
                     /locus_tag="VW749_000911"
     CDS             complement(4334..5371)
                     /locus_tag="VW749_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0174962.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(5575..6900)
                     /gene="brnQ"
                     /locus_tag="VW749_000912"
     CDS             complement(5575..6900)
                     /gene="brnQ"
                     /locus_tag="VW749_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0174963.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7071..7163)
                     /locus_tag="VW749_000913"
     CDS             complement(7071..7163)
                     /locus_tag="VW749_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0174964.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7206..7358)
                     /locus_tag="VW749_000914"
     CDS             complement(7206..7358)
                     /locus_tag="VW749_000914"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0174965.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LTDSYD"
     gene            complement(7518..8096)
                     /locus_tag="VW749_000915"
     CDS             complement(7518..8096)
                     /locus_tag="VW749_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0174966.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8150..9550)
                     /gene="pepV"
                     /locus_tag="VW749_000916"
     CDS             complement(8150..9550)
                     /gene="pepV"
                     /locus_tag="VW749_000916"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0174967.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9563..10168)
                     /locus_tag="VW749_000917"
     CDS             complement(9563..10168)
                     /locus_tag="VW749_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0174968.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10339..11139
                     /locus_tag="VW749_000918"
     CDS             10339..11139
                     /locus_tag="VW749_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0174969.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11317..12150)
                     /locus_tag="VW749_000919"
     CDS             complement(11317..12150)
                     /locus_tag="VW749_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0174970.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(12140..13984)
                     /gene="uvrC"
                     /locus_tag="VW749_000920"
     CDS             complement(12140..13984)
                     /gene="uvrC"
                     /locus_tag="VW749_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0174971.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(14023..14724)
                     /locus_tag="VW749_000921"
     CDS             complement(14023..14724)
                     /locus_tag="VW749_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0174972.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(14803..16035)
                     /gene="murN"
                     /locus_tag="VW749_000922"
     CDS             complement(14803..16035)
                     /gene="murN"
                     /locus_tag="VW749_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0174973.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(16040..17260)
                     /gene="murM"
                     /locus_tag="VW749_000923"
     CDS             complement(16040..17260)
                     /gene="murM"
                     /locus_tag="VW749_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0174974.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17372..18151)
                     /locus_tag="VW749_000924"
     CDS             complement(17372..18151)
                     /locus_tag="VW749_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0174975.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18220..19881)
                     /locus_tag="VW749_000925"
     CDS             complement(18220..19881)
                     /locus_tag="VW749_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0174976.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20056..22278)
                     /gene="recJ"
                     /locus_tag="VW749_000926"
     CDS             complement(20056..22278)
                     /gene="recJ"
                     /locus_tag="VW749_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0174977.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22555..23313
                     /locus_tag="VW749_000927"
     CDS             22555..23313
                     /locus_tag="VW749_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0174978.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23353..24117
                     /locus_tag="VW749_000928"
     CDS             23353..24117
                     /locus_tag="VW749_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0174979.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24130..24807
                     /locus_tag="VW749_000929"
     CDS             24130..24807
                     /locus_tag="VW749_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0174980.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24817..25476
                     /locus_tag="VW749_000930"
     CDS             24817..25476
                     /locus_tag="VW749_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0174981.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25734..26924
                     /locus_tag="VW749_000931"
     CDS             25734..26924
                     /locus_tag="VW749_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0174982.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27245..28126)
                     /locus_tag="VW749_000932"
     CDS             complement(27245..28126)
                     /locus_tag="VW749_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0174983.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28265..29593)
                     /gene="vncS"
                     /locus_tag="VW749_000933"
     CDS             complement(28265..29593)
                     /gene="vncS"
                     /locus_tag="VW749_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0174984.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29590..30246)
                     /gene="vncR"
                     /locus_tag="VW749_000934"
     CDS             complement(29590..30246)
                     /gene="vncR"
                     /locus_tag="VW749_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0174985.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30295..30378)
                     /gene="pep27"
                     /locus_tag="VW749_000935"
     CDS             complement(30295..30378)
                     /gene="pep27"
                     /locus_tag="VW749_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0174986.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(30558..31937)
                     /gene="vex3"
                     /locus_tag="VW749_000936"
     CDS             complement(30558..31937)
                     /gene="vex3"
                     /locus_tag="VW749_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0174987.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31989..32636)
                     /gene="vex2"
                     /locus_tag="VW749_000937"
     CDS             complement(31989..32636)
                     /gene="vex2"
                     /locus_tag="VW749_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0174988.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32649..33926)
                     /locus_tag="VW749_000938"
     CDS             complement(32649..33926)
                     /locus_tag="VW749_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0174989.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(34283..34453)
                     /locus_tag="VW749_000939"
                     /pseudo
     CDS             complement(34283..34453)
                     /locus_tag="VW749_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34596..34742)
                     /locus_tag="VW749_000940"
     CDS             complement(34596..34742)
                     /locus_tag="VW749_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174990.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            complement(34739..35194)
                     /locus_tag="VW749_000941"
     CDS             complement(34739..35194)
                     /locus_tag="VW749_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174991.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
BASE COUNT        10045 a         7976 c         6549 g        10720 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaagga ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taataaaatt
      121 ttattcaatc catctactca ttcccaaaag gttgctgtat aatgcaagac atttttctta
      181 ctgattttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactatt gaaacaatag aacgtaaata atgataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatgact ataatcatct gcatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaattgatt agggaattta aaccaacttc taacaatgtg ttatactcaa
      601 tgaaaaccaa agagcaaact aggaaactag ccgtaggttg ctcaaaacac tgttttgagg
      661 ttgtggatag aactgacgta gtcagatcaa aacactgttt tgaggttgtg gatagaactg
      721 acgtagtcag atcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagatcaa
      781 aacactgttt tgaggttgtg gatagaactg acgtagtcag ctcaaaacac tgttttgagg
      841 ttgtggatag aactgacgta gtcagctcaa aacactgttt tgaggttgtg gatagaactg
      901 acgtagtcag taaccatacg cacggcaagg cgacgttgac gtggtttgaa gagattttcg
      961 aagagtatta gaaagctcga tgaactattc cagattcatt ccactaaatt tcgaaatcga
     1021 gtaggggata atctctagcc cctctcacac caccgtacgt gccgttcggc atacggcggt
     1081 tcaactaact tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg
     1141 tttttcaagg actggttttg atatagcacg tttaagtacc gacttctgag ctactaattg
     1201 atagtggtcg ccccagccag ataccttatc cgctatatag gccttattat cacgttcctg
     1261 ttcgtagagc cacgatttcg ctatcccttc ctctgacgat tcttatttcc agcgtcagac
     1321 ttaaaacggt ctatccccag accgttttaa tccgctacct cacgatagtc agacttggga
     1381 atcgctattg ggttcaccgg tagtaggtgc ccaccgagga cttacacctc agatatacga
     1441 catgcccgtc gtacatcaaa aaaagttgag acatagtgtc ttcaactttt ttacattact
     1501 ttaactactg attaaagtga gtttacgtca actttgatac caacaccttg agtagttgtg
     1561 atagtcaagt ttgttacgta agttccttta gctgtagctg gttttgcttt ttggattgtt
     1621 tcgttgaaag ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg
     1681 attgcttgaa cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct
     1741 tcaactgctt tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta
     1801 cgtggtccaa ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata
     1861 actacgtcga agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca
     1921 aagtctgcac cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca
     1981 cgtgaagttt taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct
     2041 tttttaacgt cgatgttcaa gttgtaagca acttctacag ttgcatcaaa ttttgcaaag
     2101 ttagtttctt ttgcaagtgc tacagcttct tctacactgt atgcttttgt gctgtcgatt
     2161 ttctcaagag cagcacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag
     2221 tggttcaatc gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt
     2281 tcagtctact atttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag
     2341 cctcagtcac ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt
     2401 gttattgatt agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc
     2461 attgcagact ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt
     2521 acttgtgcac gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca
     2581 acacctgcag cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat
     2641 gatttatctt cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta
     2701 cgagcgttga actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt
     2761 ccaaccggtg gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg
     2821 acttttttag ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac
     2881 ctcccacaag tatgtttttc acatacccat ccattataca ctatttatct ggaattgcaa
     2941 gagaaaagtt tattttttgt actcaatgaa aatcaaagag caaactagga agctagccgc
     3001 aggctgctca aagtacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca
     3061 ctgttttgag gttgtgaata gaaccgacgc agtcagtagg taaggcgacg ctgacgtggt
     3121 ttgaagagat tttcgaagag tattaatcga cgtagtctcc gccttcaaag ccatagtatt
     3181 cttccaaact gagaccactt gcagcaattt ctttagcttc ttttcctaca taacgcaggt
     3241 gccattcttc agccatatag cctgtttcct tttccttgcc tttgagataa cggacaacaa
     3301 agccataatc agctgcatga tccaagagcc attgggctgc tttttcttct gtcaccaaat
     3361 caccatcagt cccaatcaca tcaaaggcca agcctgtctg gtgttcgcta tagccaggac
     3421 gggcagagta acggtcagct gctgcctttc catcttggtt gacataatct tgatagagct
     3481 tggtctgagt ttcataactt ctaaaaccac tgtaatgatc actaataggg aaacctgcct
     3541 cttgcatcgc tttgatgagt ttgaccaact ctgccttggc tgttggattt tcccctggat
     3601 tatagtcttt agacaatgga tagtgtttgt tggctacgat gatttcatcg tatttccctt
     3661 gaatgctgta gtaatcacct ttattgacca cttctgcttt cttctgggca gctccttgag
     3721 acttactacc gactgttcca tcagctttgg ctgtctgttc tgtcttagtt tctccatctt
     3781 cattttttgt tttttcttgt gaacaagctg ctagactcaa ggctagcaaa gctgtcaaga
     3841 ctaggtatct tttcttcatt tctactcctt tatttctaat agtttatcta cttctgacga
     3901 taaacgtttg actaatcttt taatctcatc cggttttgct tggcaggttt ctgctgtcat
     3961 ttcttcaaag ggaacccacc agactggtcc acgacccttg agaccatgac cattcatatc
     4021 acctgtccgt cgtggaaaca gatgccaatg aagatgagca tcgccatttc ctagcagttc
     4081 gatattcatt ttctcagcag caaaggcctt ggcaactgcc tcttggacta aactcatttc
     4141 ttctagaaaa cggagtcttg tctccttttt caaatggtgc aattcgctga catgctcctt
     4201 ggctagaaag agactatagc cttcaaaata ctggtggtct ccaaccacaa gatagcctgt
     4261 ttccaactct ttgacaaagt aaggattttc ttccttcttg atgaggtcaa ttctctgaca
     4321 aataaggcac atattagtcc accaacgtgc tcttaagata agcatcgacc attcgttctg
     4381 ttgcgatcac cgagtcaata tgggtacgct cataggaatg gctagactct ataccagcac
     4441 cgagaagggc gtgtttgact tctgcccctg cagacatagc cgctgaagcg tccgaaccat
     4501 aaaatggata gatatccagc ttaaatggaa tatcttgctc tttcgccaaa gccaccaaat
     4561 gttgacggaa gtcatagtga taaggtccag aagcatcctt gacacagata gacactgtat
     4621 attcgtctgt ttgctggtca tctcccatgg ctcccatatc cacagccaga tattctacta
     4681 cctgagcagg aatgttagag tttgcaccgt gtcccacttc ttcaaagact gaaaaagcaa
     4741 aatgagttgt tacgggcaat tcaatcttct cttccttata aatgcgaagg agattgagca
     4801 aaatcgccgc actgaccttg tcatccaaat ggcgagactt gataaaacct gtctctgtca
     4861 cgacagttcg tgggtcaaaa ctgataaaat caccgacctc aatgccaaga gcacgagttt
     4921 ctttttcact agttactttg gcgtccaaac gcacttccat attgtcttgc gtgcgttctg
     4981 cagttcctgc atccttatag acatggcaag aagtttggtg gatgaggatg gttcctgata
     5041 ctttttcacc tgtgctagcc acatgaatgg tacagttttc tccttcaatc atgttccaag
     5101 gaaagccacc gatacggtcc attttgagac ggccgtctgg tttgacagca cggacaatag
     5161 caccaagcgt atctacatgg gcagtcacat agcgatgttg ctcatcattt tgacctttaa
     5221 tagttacatt gacaccgccc ttggatgtgc gaaccggctg gtaaccaaaa ccttctagag
     5281 tcttaactaa atagtccgca atctcacgag taaagcctgt tggcgacgca atggctgtca
     5341 gttctttgat atattctact gtttgattca tttcttcacc tcttttgcta cctattataa
     5401 cacatttatc atcggataaa aaaagaaaat cactcctgta gacttgacta caaaagtgat
     5461 tttatactca atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt
     5521 acgacaaggc gacgttgacg cggtttgaat ttgattttcg aagagtatta gtgattattc
     5581 catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca agattccaac
     5641 aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc taacaagatt
     5701 tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa taactgtaac
     5761 cacagcaatt gtcaactgca tacctggttt tgaaagagca acaaatttgt tgacaatgac
     5821 aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa ttgagtactt
     5881 gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa aggctgtcgc
     5941 ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg ttgacacaat
     6001 caaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga agagttgagc
     6061 tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg gtgttccacc
     6121 cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac cgatgtaaag
     6181 agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa tgtattcttt
     6241 cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacgctaa aggccactga
     6301 ggcaagggcg tccaaggtat tgtaaccttc taggaaacct gtaccaaagg cagaagcttg
     6361 ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc ccagaacgac
     6421 caagataaca atcaaaattg caaagactgg cgttaaaata cgtccaatgc ggtctaagat
     6481 ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg taaatacaat
     6541 caagccaagt cctttatttg catccgacaa aagggggcta atccctactt cgtaagctgt
     6601 tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa ctgagaggta
     6661 aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatacc ctttaggatt
     6721 tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga caaaacctgc
     6781 gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa aaatcaagtt
     6841 ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt ttttagccat
     6901 aaaaatctcc ttcatattta taaaatactg acctagtata ccacgattag gagtctgaaa
     6961 aaagcatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag aattatctaa
     7021 aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt ttaaagttct
     7081 tcaaaggcta acatgccacc ctggacattg ataacattat aaccttgttc taacaggaat
     7141 tggcaagcac gcgccgatct cattccagat ttgcaaataa tataatgcaa gcgatctttg
     7201 tccaattaat cataactatc agtcaattga ctaagcggta ggttgtgggc accttctaaa
     7261 tgaagagctg caaactcatc cacttctctc acatccacta gagaaagctg gtcgttttgg
     7321 taaagctggt aaaatgcgtc aaaggctatt tctttcattc tttttcttct aatactcttc
     7381 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc gtatgttacc gacttcgtca
     7441 gttttatctg caacctcaaa gctgtacttt gagcagccta cgactagctt cctagtttgc
     7501 tctttgattt tcattgacta taaaatggtt ttaattcttt ttttcaaatc tggcactact
     7561 tctgcctcaa accaaggatt tttggccatc cagatttgat ttcgtggtga tgggtgaact
     7621 agcggaaaat aggctggcag atagtcttta tagtgtttca ccctctccgt taccttccca
     7681 ctgattttct cctgtaaata gtaggcttgg gcatattgcc caatcaagag ggttaactga
     7741 atatcaggca attcctgtaa gagctgcgga tgccattttt ctgcaaaacc tgtacgaggc
     7801 ggaagatcac ccgacttgcc atgtcctgga aagtagaaat ccataggcaa aacagcaaaa
     7861 taacctgaat tgtaaaaggt atcttcatcc acacctagcc agtcccgcaa gcggtcacca
     7921 cttttatctt tccagtaaag gcctgcttct tgagttttaa gtcccggagc ctgaccgatg
     7981 atattgatgc gagcagtttt tggcgctgca aagagaggct caatgccacg ctctgtatag
     8041 ctggcattct gtgaatccgc catgatagcc tgtttgattc tttcgatttg agacatctac
     8101 tttccctcca aaaagaagtc caagcataag atctcagact tctatcgttt tatttgatca
     8161 attcgtaaat agcttcggca taaattgctg ctgctcggaa aagatcatcc aaggcgataa
     8221 attcattggc ttggtgcatg gtatcaatcg agtctgggaa catagcaccg taggcaactc
     8281 cgcgttctag caagcgacca aaggttccac caccgatgac ttgttcatga cctttaaggc
     8341 cagtttgttt ttcatagata ttcaacaagg tttgcacaag tggatcttcc attggcacat
     8401 agtgaggcgt gtgaccgtgt tcagacaggc taacagaaac aactggcaag ttttcaagga
     8461 ttgacttgat ttgttctgga cttgttcctt ttggatagcg gatgttgagg gcaatggtat
     8521 tatcagcact tgtttcatcg aagcggaaga cgccggcatt catagaaaga gcacccatct
     8581 tttcatccac atgagcaatc ttaagatttt caccctcatg atcgttcaag agaattttac
     8641 ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc aaactggctg aggaagaggg
     8701 caaggtaagt tgcgccattg acacctgaag caggcatagc accgtgggct gatttaccaa
     8761 tgatcgtcac cttgtatttg ccagcttctt cttggagttc tcctctaagt ttgtgttctg
     8821 caacaaaggc atctagttta gcttgcaagt cagccaagtc acctgaaacg actgctgttg
     8881 ctgattctgg taccatattt tcacgtaaac cacctgtaaa gctgtgaaga cgggcaacac
     8941 ctgtattttc tcctgcaaag tggaggtatt ccgtgatatt tcctttttca ccattgatga
     9001 ttggaaattc agcatctggt gagaaaccga aatctggttt ggcaagtcct acgtgctcaa
     9061 agtagtagtc catgtctgcc cagcctgatt cttcgtctgt tccaacgatg aagcgaactt
     9121 tcttagaagt tggaagaccc aattctttga tgattttcaa accatagtaa caagctgttg
     9181 taggaccctt atcgtccgaa gccccgcgcg cataaaggcg accatctttg atagttggtg
     9241 tgtaagggtc tgtgtcccaa ccgctaccag caggcaccac atccatatgg gcaaagattc
     9301 cgagaacttc ttctccatca ccaaactcaa aatgtcctgc atagttatca acattcttag
     9361 ttgggtagcc atcgcggtct gcgatttcaa ggaatttctc caaggctttt actggaccag
     9421 gcccaaatgg atgctgggca tcagccttgc tgtcatcacg ttctgaattg atttccaaaa
     9481 ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc tacttctgct gtaaaatcaa
     9541 ttgctgtcat tttttcttct ttctatcttt tctcgatgat ttcatctact ggcaagcggt
     9601 agcttggttc caatttttcg tctgtataac ccactgtgat caagagttct gggcggaaac
     9661 ggtcttcgat ttccaaaact tcattaactt ttgatttgtc aaaaccaagg ataatattgg
     9721 aaccaattcc ttggtctgta agagcgagaa ccaagttcat agcaaccaaa cctgcattga
     9781 gtgctaggta gtcgctgact tgttgttcat tgtagcgtgc aaattcagct ggcaaatttt
     9841 tcatgaagta ttgaagttgt tcttctgaga aattgttagc accaccaact cgggcaatct
     9901 tacgagcgcg tttggcaagg tctgtatctg taaatagggc aatggttaca ggtgctgatg
     9961 atacctgttc aaaattggaa ccataagcta actttgccag ttcagcattt ttctcacata
    10021 ccaccacaaa tttccaaggc tggctgttgt gggcgcttgg cgccaaggtt gcaatttcga
    10081 tagccgtacg cacatctttt ggatcaacag gcttatcagt gaaatgcttg gtcgcatgac
    10141 gttttttatt taattcaaga aatttcataa tcgatttcct tttctaattc tactgcttcc
    10201 attctaccat aatttgaaag agcttgcagg gatttttcat gattaagttt ttctatcaca
    10261 gacataaaag atatatattg gtttatcagg aaagtttctg ataaactagc aagtacttta
    10321 catttgaatg gagacagtat gaaaaaattt agcctattac tagctatcct accatttttg
    10381 gttgcctgtg ggaatcaagc tacacccaaa gagtccagct ctcaaaagac aatcgtcctt
    10441 gctacagctg gcgatgtgcc accatttgac tacgaagaca agggcaatct gacaggcttc
    10501 gatatcgaag tcctaaaagc agtggatgaa aaactcagcg attacgagat tcaattccaa
    10561 agaactgctt gggagagcat cttcccagga cttgattctg gtcactatca agcagcagct
    10621 aataatttga gttacacaaa agagcgcgct gaaaaatacc tctactcgct tccaatttcc
    10681 aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt tgacttatct tgaccagatc
    10741 gctggtaaaa caacacaaga ggataccgga acttctaacg ctcaattcat caataactgg
    10801 aatcagaaac acactgataa tcccgctaca attgattttt ctggtgagga tattggtaaa
    10861 cgaatcctag accttgctaa cggagagttt gatttcctag tttttgacaa ggtatccgtt
    10921 caaaagatta tcaaggaccg tggtttagac ctctcagtcg ttgatttacc ttctacagat
    10981 agccccagca actatatcgt tttctcaagt gaccaaaaag agtttaaaga gaaatttgat
    11041 aaagcgctca aagaactcta tcaagacgga acccttgaaa aactcagcaa tacctatcta
    11101 ggtggttctt acctcccaga tcaatctcag ttacaataac actcttcgaa aatctcttca
    11161 aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccta cggctagctt
    11221 cctagtttgc tctttgattt tcattgagta taagatatat aaaagcgatt ggactaccaa
    11281 tcgtttttag tttgcattgg ttattttagg aaactcttac aaaaaatcaa aaaaattctt
    11341 cacatcctct acatacctat gcttttctat taagcttgct aatagtttca gattgtgcct
    11401 ctgatagtta tcttcacgac gtagttcttc atacatttcg ataaagggaa gccccttgga
    11461 tttggccaat tctaactcag cctcgtaatc ataagcaact ttacgaaatt ggatattgag
    11521 taattcccca tcttcaacct ctatcacggc atactgggca cggtgatttt ttaacgcctc
    11581 ccaattaaaa tagggcatgc caatcgaccc tggattgatg atttgttgcc ctttactgcc
    11641 gtagcgaagc aactgcttgt gaacatgacc ataaactgcc acgtccgttt ccgcatctag
    11701 cagttggtca aatttctctg tatcattctc aactagcaag tcaccaccat agtttttgtc
    11761 aggtaaatta tgagagatag aaaagcgcaa tccgtcaatt tctttctttt ccagcaaagg
    11821 caagcttcgt agccagacaa tcgttgcagg atccattcgc tccatcaaaa actgggtcat
    11881 gcgcattgac tggatttctt tcggatattc caaaccatat tcgccatcca agacctcaag
    11941 gacacgatca tcccaattgc ctcgaacact tgctgtgata ggaaggtcct ttagcagggc
    12001 gactaagtca tttgcgcctg gaccaggaag aaaaatatct ccctgaagcc aatattcact
    12061 ggccccttga tttttagcat ctgcaatcac tgcttctagc gccgtcgcat tgccatgaac
    12121 atctgataaa attgcgattt tatggttcat tgtggtttcc ttccgtttgg taatctactc
    12181 tttcttctgc tacttgaggc aaggcttctc cctgcgggtt caactttctt tgcacagcct
    12241 ctgcaacgac tctaggtacc ccaacttcga caatctcatc cacactggct tccttgattt
    12301 tggtcaaaga cttgaaatgc ttcataagat tctgcttgcg tttaggtccc agaccgtcaa
    12361 tcccatccaa ttgagatgag aaagaatttt tggagcgcag ttggcggtgg aaagtgatag
    12421 caaagcggtg cacctcatct tggatgcgtt ggaggaggaa aaattcctga gaattgcgag
    12481 acaagtccac cacctcaagc ggatctccaa agagcaattc atgggtttgg tgcttatcat
    12541 tcttttgcag cccagcaatt ggaatatcca agcccagttc ctcttggatg acttgcttag
    12601 caatattgac ttgaccttgc cccccatcaa tcacaatcaa atctggagga gtcaaagcct
    12661 cacgctgtac tcgaccatag cgtctgcgaa tgacttctct catactagca tagtcgtccg
    12721 gcccaacaac ggtttttatc ttgtacttac ggtaatcttt tttacttggc ctgccgttaa
    12781 caaagaccac catggctgaa acaggactgg tccccatgat gttggagtta tcgaaggact
    12841 cgatgcgaac tggagtcgga atttggagca aacgtcctag attttcaata gctccttggg
    12901 tcttttcgac tgatttttct agcagattga acttctgctc tagactaaca cgagcatttt
    12961 ttatggctag attgaccagc tgttttttct ctccacgttg gggtttgaga atcttggtat
    13021 ccaccaaagc cttgacagct tcttcgtcaa tatcctgcgg aatcagtacc tcattgggaa
    13081 ctaggtgaga tttttcttga tagaattgtc ccacataggt caagaaatcc tcatctggat
    13141 cattgaagta ggggaagaga ttgacatcgc gctcgatgag cttgccctga cgaacaaaga
    13201 aaacctgcac acacatccag cccttatcca catagtagcc aaagacatcg cgattttgga
    13261 gatccttagc catgacccgt tgcttggttc gaagtgttcc aatggcctga atcaggtcac
    13321 ggtattccgc tgcccgttca aactccatac tttgtgctgt tactgccatt ttactcttga
    13381 gatcatcgat gattttgtca tcctgacctt tcagaaaatc agacacctcc tgggccatgg
    13441 acttgaaata ggcctcgtca ttcttacaga tggtgtgggc catacattgg ccgatatggt
    13501 agtaaaaaca gaccttagag ggcgggttgg tacattttcg aaaagggaaa atcctatcta
    13561 gaagtcgctt gatttcattg gctgccccca catctggata agggccaaaa taaagaccac
    13621 cgtccttttt gacctgacga gtaatgataa gccgtggata gtgctcattg gtgattttga
    13681 taaaaggata agacttgtca tccttgagca tgatattgta cttgggctta ttttccttga
    13741 tcaggttgat ttccagcaga agcgcctcaa tattagactc cgtaacaata aattcaaaat
    13801 ccacaatttc agacaccaag gcctctgttt tggtatcatg acttccacgg aaataagacc
    13861 tcacgcgatt acgcagattt ttagcctttc ctacatagat aatggtgccg tttttatcct
    13921 tgtaaatgta gcaaccaggg ctggtcggca agagctctag ttttggttta atcaagttgt
    13981 tcatagttcc attatagcaa aaaagtaggg aaagatagta ccctactcat tagtctcata
    14041 tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac ctgctggttg
    14101 catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact catgttctgc
    14161 cgtatggaca aggcgttcat aggaatagcc atagtatgga ttggacaaat aataatgatt
    14221 caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac tttccgcctc
    14281 tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg ccttactaga
    14341 ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga ttgcttctaa
    14401 ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag cagaggcctg
    14461 tggccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag gcagttgccc
    14521 tgttttctcc cattggtcaa tactttgttg accaattttt actgaccgtt ctgcttgctt
    14581 tagcgctcct tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa gcacacataa
    14641 gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa agaaagcccc
    14701 tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataaa aattatttta
    14761 ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc ctactatttt
    14821 tttgagtaac tggatagctt tgtattttaa aggagatgga tggtaacgga aagtacctgc
    14881 tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat cacttccatc
    14941 aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta tgctttccaa
    15001 cataacatat ttttgaagca gtgcaggggc atagaactta ttaaactcag tgtaggaacc
    15061 actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag ctaaaacaat
    15121 atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa cttcaaacgt
    15181 ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat gaggattttt
    15241 actcaaatca agtcgcaact tgtccaagtt ttcttctagt ttattttgtt caccttgcaa
    15301 tttgctcata tagtccgaaa aatttaagct tgctatgaga aactccgctt gttctccaaa
    15361 agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc tacgttcaga
    15421 ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact ttttcaatcg
    15481 aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa aacttttaag
    15541 caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg gttctccacc
    15601 tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaac cttgaataat
    15661 actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat aagtttcata
    15721 aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta actctgcata
    15781 aaaaactgga agagcatctt gttgggtata aatcggcccc gaattgagtt ccatatgcag
    15841 accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc cttcttgttt
    15901 caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca tctggacaga
    15961 ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt ctttcgtgag
    16021 tgttgttagt gccatatact tactttctat gtttttttct taatgtttta cggaaatcaa
    16081 gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca cccaagtatt
    16141 cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg agagagtttt
    16201 caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga gccgtttcat
    16261 accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca gcatatatat
    16321 tgacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact ctcgcttgac
    16381 ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct ttttccttct
    16441 tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa ggtctcttcc aaggctctat
    16501 ttttcgctaa ctgttcttct aattcttgcg aacgtttaga aacatccaag gtggccaagg
    16561 tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct tcattcctca
    16621 aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa tctaatagtt
    16681 ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata gcctgttttg
    16741 ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc tgaatacgag
    16801 gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc atttgttgca
    16861 aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg attaaacttt
    16921 gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg cgagcatagg
    16981 acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc aatataggtc
    17041 ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa atactagctg
    17101 tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa ttagacttaa
    17161 cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg acaaactgat
    17221 catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct ctttcctcca
    17281 gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca tattttattt
    17341 tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct aatttgaaat
    17401 caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac cactcgtgag
    17461 ttccagcact atggctatag gtcacatcaa aacctagttt tttgagattt ttcactgcga
    17521 gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt ttggtctttt
    17581 tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag tctctaatct
    17641 ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca ggagaaaagt
    17701 tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt gtcgtaagag
    17761 ccagtttgaa gcagccgtag cctcccatag aaagaccagc gataaaggtc ttttcacgct
    17821 tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct gctagagccg
    17881 tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta ttgggcataa
    17941 caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta agccaactat
    18001 tatgatttcc agacatcccg tgcaaaaggt acaagacggg aatatcttca cactctggtt
    18061 cttccactcg attggcatca gggtagagga cattcacccc ccactccata tccaatactt
    18121 gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt tctataagaa
    18181 aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt ccatgactac
    18241 tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca aattatctcg
    18301 aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagataat cttctaccgt
    18361 ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga gataaacaaa
    18421 tccacgcgtg tgaacacgag ccctagccac aattttcttc tcacgacggt tgactgtaat
    18481 agccacgatg aaaattccat cctctgacaa gaccttacgg tcacgaagaa caacatttcc
    18541 aacatcacca atggcattcc catcaatcaa gatatctcct gctgaaaccg atccagctgg
    18601 aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga aaatgcgttc
    18661 tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac gatactcccc
    18721 ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca aatcacgcac
    18781 atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc cacctgcctg
    18841 ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg gagccgtagc
    18901 aatatagacc aggtccccat ccttgatttc tacataacga tggcgaccaa tcgacatctt
    18961 acgaagtcca ttgataggtt cacccatacg acctgtctca agaataatca actcatggtc
    19021 ttcaaagcga gacatatctt taggcttaat caagagaatt tcgttggcta aagacaactt
    19081 cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca agacgatacg
    19141 tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat tactggaaac
    19201 agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt catccctaac
    19261 ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac tgaggagagc
    19321 caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat aagattcact
    19381 agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg atgtcttcaa
    19441 gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa ccactgtccc
    19501 accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt tcttaacggc
    19561 atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc caaatacagg
    19621 aactttagcc tctgccaaga gataaggtag agcaccaatg gcatccgcat gcccgtgggt
    19681 caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt ttggaatcac
    19741 cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca aaacaaaaat
    19801 ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac caccaagtgt
    19861 tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga ttatagggca
    19921 attctaccct cttattctaa aagttctgat actttcagcc gaatcttttc ctaccattat
    19981 accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt tgatttccca
    20041 actctttcct aacttctact ctttttccat caaaaaatca taaatttctt gcaccgtacc
    20101 cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa tttgactttc
    20161 tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt ttatcgtcac
    20221 aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt gaatattaag
    20281 atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact ggtaaatagt
    20341 cttgtacaat ttagcaaact gatctctagt cccataacct gtcagataat aggtcttgtc
    20401 aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg tcttcagctg
    20461 agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa gatttggcag
    20521 ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt ttccacgaat
    20581 gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga gggcagtttg
    20641 gccattccat tggttgacag acaatttaac cgctaactct agattcttgg tttgagaaaa
    20701 ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct cacccttgga
    20761 aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt cgacctgaaa
    20821 attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta aacgttcaaa
    20881 acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta ggtttaactt
    20941 attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa cctgagataa
    21001 atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac ctccaaaggc
    21061 gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt ccacactacg
    21121 agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct gtcccaattc
    21181 ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt ccttggccaa
    21241 gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga tagactgaac
    21301 gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat gcgcttcctc
    21361 atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc gacccaaggc
    21421 attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt tggcagcaat
    21481 cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca acatttccag
    21541 accatattga actaagatac gattttcatc cgtcagactc accatatctg caatagttcc
    21601 aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac aagccaactt
    21661 gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg gatgttcagg
    21721 atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt ctgtcacaat
    21781 gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa ccccattgtc
    21841 caccgtcaca atcaaggaaa ttccttcttg ctcgataaag tatttataaa cactagcatt
    21901 agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag caccaagttg
    21961 ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat agtctccata
    22021 aacgagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg ccttgtccat
    22081 atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa acttcttcag
    22141 actttcttgg tcctgaatcc ctctctcaaa caataaccga gccacctcag gacccagtcc
    22201 agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa actgccattc
    22261 ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg cttcattata
    22321 acatgattta gacgttttct ctatccagat tgctttttta taacatttta tagtatattg
    22381 aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt gactgtcccg
    22441 atcgattttt cctgttctta tttcactata gtgaattttt tcagatatga tttgacaaga
    22501 acattctttt attgcagaat cgtgttataa aatctaacat aaaggagttc tctcatggtt
    22561 ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcact ccgcaacatc
    22621 aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag
    22681 tccactctta tccgtacgat caatggttta gaggctgttg acaaaggaag tctcctagtc
    22741 aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc
    22801 ggcatggttt ttcaacattt taacctttat ccacacaaaa cagtgttaga aaacgtgaca
    22861 cttgcgccca ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac cgccaaaaaa
    22921 tatctggaat ttgtaaatat gtgggacaag aaagattcct atcccgccat gctatctggt
    22981 ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc
    23041 tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg
    23101 cagaaactgg cgcgtgatag gatgaacatg atcatcgtta cccacgaaat gggctttgct
    23161 cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt agatacgaca
    23221 gatgtcgata acttttttga caatccaagc gaacctcgtg cccaacaatt cctcagcaaa
    23281 attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaattcttt
    23341 ttatcagcat tattgattag ccttttcggc cttgctgctg ccaaaccagt ccaggctgat
    23401 acaagtatcg cagacattca aaaaagaggc gaactggttg tcggtgtcaa acaagacgtt
    23461 cccaattttg gttacaaaga tcccaagacc ggtacttatt ctggtatcga aaccgacttg
    23521 gccaagatgg tagctgatga actcaaggtc aagattcgct atgtgccggt tacagcacaa
    23581 acccgcggcc cccttctaga caatgaacag gtcgatatgg atatcgcgac ctttaccatc
    23641 acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga cgcttctgga
    23701 tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg caaaaccatc
    23761 ggagtcgccc aaggttctat cacccaacgc ctaattactg aactgggtaa aaagaaaggt
    23821 ctgaagttta aattcgtcga acttggttcc tacccagaat tgattacttc cctgcacgct
    23881 catcgtatcg atgccttttc cgttgaccgc tctattctat ctggctacac taataaacgg
    23941 acagcactac tagatgatag tttcaagcca tctgactacg gtattgttac caagaaatca
    24001 aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa ggatggtagt
    24061 ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gtcataccgc agattaagga
    24121 ggatacccta tgacagattt atcatcttgg acagcctatt ttcaggattt tggacaattt
    24181 ttcaatggtt tcctctttac tcttgcccta gcgattggat cctttatcct cgccatggtc
    24241 ttaggaatct tctttggtgc catgtcaacc agtaaacgtc caattttacg cattttagct
    24301 cgcatctttg tggaatttta ccaaaatact cctctcttgg tgcagtttgt tattgttttt
    24361 tatggcctac ctcttatcag tgaccatatc atcatgattc caatttattg gacagccgtt
    24421 ctctgcgtgg gactctatca cggcgcttat atcgctgagg ttattcgttc agggattcag
    24481 tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta tatcagtgcc
    24541 atgcgcttga ttaccttgcc tcaggccttc cgcatcattc tccctccatt gaccaaccaa
    24601 attgttaacc tcatcaagaa cacctctact gtagctatca tctctggagt agacttgatg
    24661 tttgtgacta agtcttggtc ggctctcaac ggaaactata tcccagcctt tttaggtgct
    24721 actcttctct actttgccct atgcttccct gttgcccagt ttggtcgcaa gatggagcaa
    24781 gccaacaaaa aagcctattc actttaggag gttactatgg aatctatttt agaagtttta
    24841 accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta tatttctctg
    24901 attgccatca tcctctctac tatcatcggt acggtgctag ctgtcatgag aaatggcaaa
    24961 aatcctgtct tgcgaatcat ctccagcatt tatatcgaat ttgtgcgcaa cgttcccaac
    25021 cttctctgga tttttactat ctttttggtg ttcaaaatga aatccacacc agcaggtatt
    25081 acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg cggtctcaat
    25141 gccgtagaca agggacaata cgaagcagga atgtcacaag gcttcacctc agcccaaatc
    25201 ctctactaca tcattctccc acaagccatc cgcaaaatgc taccagccat catttctcag
    25261 tttgttaccg tgattaagga taccagcctc ctctactctg ttatcgccct acaagaactc
    25321 tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt cttcagtctt
    25381 tgcatcctga ttgccctcat ctacttcagc tttaacctag caatttctag cctgtctcat
    25441 atgctagcca aacgttggca acaagctgca gaataatact cttcgaaaat ctcttcaaac
    25501 cacgttagct ctatctgcaa cctcaaaaca gtgttttgag caacttgcgg ctagcttcct
    25561 agtttgctct ttgattttca ttgagtataa acagccactc tccagttcaa ttggagagtt
    25621 ttttgatgag agtagatatt tatagacctc aatttgacac catacatttt ctatgataaa
    25681 atgtaacaaa tttatttaca acaaatcgaa atctaaatga aatggaattt tctatgaaat
    25741 cagtcaaagg actactcttt atcatagcta gttttatctt gactcttttg acttggatga
    25801 acacttctcc ccaattcatg attccaggac tagctttaac aagcctatct ctgactttta
    25861 tcctagccac tcgtctccca ctactagaaa gctggtttca cagtttggag aaggtctaca
    25921 ccgtccacaa attcacagcc tttctctcaa tcatcctact aatctttcat aactttagta
    25981 tgggcggttt gtggggctct cgcttagctg ctcaatttgg caatcttgcc atctatatct
    26041 ttgccagcat catccttgtc gcctatttag gcaaatacat ccaatacgaa gcttggcgat
    26101 ggattcaccg cctggtttac ctagcctata ttttaggact ctttcacatc tacatgataa
    26161 tgggcaatcg tctccttaca tttaatcttc taagttttct tgttagtagc tatgcccttt
    26221 taggcttact agctggtttt tatatcattt ttctatatca aaagatttcc ttcccctatc
    26281 tagggaaaat tacccatctc aaacgcttaa atcacgatac tagagaaatt caaatccatc
    26341 ttagcagacc tttcaactat caatcaggac aatttgcctt tctaaagatt ttccaagaag
    26401 gctttgaaag tgctccgcat cccttttcta tctcaggagg tcatggtcaa actctttact
    26461 ttactgttaa aaattcaggc gaccatacca agaatatcta tgataatctt caagccggca
    26521 gcaaagtaac cctagacaga gcttacggac acatgatcat agaagaagga cgagaaaatc
    26581 aggtttggat tgctggaggt attgggatca cccccttcat ctcttacatc cgtgaacatc
    26641 ctattttaga taaacaggtt cacttctact atagcttccg tggagatgaa aatgcagtct
    26701 acctagattt actccgtaac tatgctcaga aaaatcctaa ttttgaactc catctaatcg
    26761 acagtacaaa agacggctat cttaattttg aacaaaaaga agtgcccgaa catgcaaccg
    26821 tctatatgtg tggtcctatt tctatgatga aggcacttgc caaacagatt aagaaacaaa
    26881 atccaaaaac agagcttatt tacgaaggat tcaagttcaa ataagtaatc atactctcct
    26941 gggatttccc aggagagttt tttatagcca aatgaaataa gacaggaacg atggaatttt
    27001 ggcattcaaa tcaattgata agaatgtttt atagtggagt gaaataggat acgaacaaat
    27061 tgattaggaa aatcaaatga atttatagaa atcttttagc agttatgttg tcctattcta
    27121 gtttcaaaac gctatagaag cagcattgtg ctagtctaga ttcagtttac tatactaaaa
    27181 cgagtagctt gaaatcaaaa aacccaccct cacaggcagg ttttatctgt attattcagc
    27241 tagattatgc tttaccttct gaaccgaata cgtcgatacg ttcttcaacc gatgcttgga
    27301 tagcttttac accgtcagcc aagaatttac gtgggtcgaa gagttttttc ttgtcgtatt
    27361 ctgcttcgtt tgcttcgtag tcacgagcaa atttacgagt tgcgttagcg aatgcgattt
    27421 ggcattctgt gttaacgtta actttggcaa caccaagttt gatagctgct tggatttgct
    27481 catcaggaat acctgatcca ccgtgcaata cgattgggaa tcctggaaga gcttctgtca
    27541 atttttgcaa gtggtcaagg tctagacctt cccagtttac tgggtaaggg ccgtggatgt
    27601 taccgatacc agctgccaag aagtcgatac cagtttcaac cattgcttta gcgtcttcga
    27661 ttggagccaa ttcaccttta ccgatgattc cgtcttcttc accaccgata gtaccaactt
    27721 cagcttctac tgagatacct ttagcgtgtg ctttttcaac aacttcttta gccaatttaa
    27781 ggttttcttc aactggaagg tgtgaaccgt caaacatgat tgaagtataa ccaacttcga
    27841 tacactcaag tgcatcttcg tagtgaccgt ggtcaaggtg gatagctact ggtacagtga
    27901 tacccattga ttcaacaagg ttagcgatca agttgcgagc aactttgtaa ccacccatgt
    27961 atttagcagc acccattgaa gtttggatca aaactggagc ttttttagct tctgctgcgc
    28021 gcaagatagc ttgagtccac tcaaggttgt ttgtgttaaa tccaccaact gcataaccgt
    28081 tgtcacgggc tgcttggaca aatttttctg ctgaaacgat tgccatttta tcaggcctcc
    28141 tgtatatttt tatgggtcat cccatttaca ttgttcattt tatcactttt tgccaaaaaa
    28201 atctagtttt tcccgcagtt tcgattgatt ttcttctaac tccatctatg taaacccttt
    28261 ctccctagtc ttggacgact tttggaaaat ctataaagaa ggttaaacga ttctcctcca
    28321 tctcgaaacg ataagctaat ttttcatgtt ctaatagact cttaaccaca aagagcccca
    28381 taccagaccc cttgaccttg cgactagcat tgtcagaaaa agactgggct agtttttctt
    28441 gttcctctga gctacagcta ttttcgataa aaagttctcc ttctctttct ccaattcgaa
    28501 ctaagccacc tggaacagag tgcttaatgg cattgctgat gagattagaa agaatcaact
    28561 tcataactga tgggtttaga taagcctgct gatgggtcaa actattgtct atctggagct
    28621 ctctttcctt tgctagcaag gcataatctt tgaccagatt ttgcgtcatc tggaggaggt
    28681 caattgtttc cctatcatct cgcaattcct gcacagaaga gagggaaagt atctgcagaa
    28741 catggtgatt gagttcatcc acaatcccca aggcaactcc cagatactgg tctctatcct
    28801 tataacgacc gatattctct ctcatatttt cgattaggat tttcaaacta gccagcggtg
    28861 ttttcaattc atgagaagct cctcgtagga attcgacctt catcttctcc agctggagaa
    28921 tggcttcatt cttttcatgc aagtccgcaa taacagtcaa gagatgctgg tagaggctat
    28981 tgatttgttc cttgagatta cctatctcat ccttagaatc cacgcgcaat cgcacttggg
    29041 aatccaggtc catcatccga cgggtcaccc gcttgatttc caaaatcggt gcaacaatag
    29101 tccgagcgta gatgtaggcc accaagaggg aaatcagaaa ggaggccagc aaggtatagg
    29161 gaagaaactg gagactgatt tgctccgctt ccttttgtaa atccatggaa gctagaaact
    29221 ggagaatcat agtaccaccg tcttgcgttt tcacctcgcg ctcctcaata aagagagagg
    29281 ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac ttctaacttg tcctcggtca
    29341 tctcaccttt gacggtcccc ttgatatcac tagtctggga atacaagtct aacacttgct
    29401 cgatactctg cctatctttc ccttctaggg actgggcaat ggctgttgcc ttttgaccaa
    29461 tggtttcctg acgatgactc agataagtcg aaggaaaaag aaaataaata gctaaatgaa
    29521 ggcagataac cagaacacta aatatcgaga aggtatagat aaatatcttt gcaaataaac
    29581 ctgttcgttt cattttcgct ccaatttata accaacattg cgcacagtga ggatacaatc
    29641 caagtctagc tttttccgca attccttgat ataaacatca ataacacggt caaagggaac
    29701 ctcatctgtc gctttccaga cggcatcgat aatctgagat cgagtcaagg cccggccttc
    29761 atttttcact agatagtcca gaatttccaa ctctttggca ttgataggca cttcttgacc
    29821 tgcgaggctt gcactgtagc tttcaaagtc caccttggta tccttgtaag aaaagattcg
    29881 tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc acttttaaaa gggagaggga
    29941 gaaaggtttt tccagatagc catctgccaa agaggcaaag gcactcatct tgtattcctc
    30001 atcttgaaaa gctgtcaaca tcaagacagg aacctgactg gttttacgaa tctcagctag
    30061 gacttctaag ccgttgagct tgggcatctg gatatccagt aaaaccaggg ccacctcata
    30121 gctagaaaat tgctccagag cttcctgacc gtccgctgcc tcaatagttt catagccaca
    30181 atccgtcaaa taatcactga ccccctcacg gatcatctct tcatcttcta caattaaaat
    30241 tttcatactt taactgctct ctatttttta tttttcttag aataaatacc taccctattt
    30301 tctattatag tctcttgctg gccttttgtc tgcaagcaac tgaccactag ataaaacgtt
    30361 gtgaaattcc tttctcataa attccataac tttagtatat tatatttaag cactaaagta
    30421 caaagaaagc aactgaaagc aatgattttc accactgctt tcggatttat tttgaattgt
    30481 taaatagcca ttcctatcca ctattcttga atagaaacac aagatgcaat ctttattcta
    30541 gactcatttt ttcaaattta ttcaccatcc agcaagagct cttttggttg ttttctaagg
    30601 agattgcttg aagcaagcgc cataacgaga accactagaa ccaaggcaag gacaaaaatg
    30661 atgataaagt ctgatgtctg aatggaaatg tctaggctcg acaaggtctt gctaaagcca
    30721 tctacttctg caccaccacc aaggttagag gcttgagccg ccttactagc ctgtttggca
    30781 acacctgaag tcacattggc aaggacagtg tttccaattg cacgggcagt gtaattagct
    30841 aggaagtaag cagaaactag agcagggata gcaatcaaga tagattcggt gatgaattga
    30901 cccaagatac ttgcctgctt gaggccgata gagaggagaa ttcccacttc cttgcgacgg
    30961 gcgttgatcc aaaggctgag caagagggca aggaggagaa ctgagaagct caagctaccc
    31021 cagaagagga ggttggccat cttgtacata ccagagatag attgctcaag agctgggtag
    31081 ttagaggagc tcttgacgag tgtgtagctc ttccagttga taccactgat gccattcaac
    31141 tctttcataa catcatccaa gttcttgtct gctgttacaa agaaggttgc gtccccataa
    31201 atggctgtgt cttctgtgta tccataaagt tttgcagcag tgtgaatgtc tgtaatagct
    31261 gtgttttcgt aaagttcttg tgagtaggtt actgctgact tattatgacc atcaaagagt
    31321 cccttgattg tcacttcaac tgtttccttg gctccttttt cattatctgc atcgtagata
    31381 ttagagtcca gtttaacctt gtcccctact ttccagccgt gtttggctgc caagtccttg
    31441 tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct ctccttcgac tagtttataa
    31501 gaaccagaga caaacttgtc ttctttagag gagtcattga cacctgtaat catcaagcta
    31561 cttccaaaac gcttggcacg atcagcagtg agattcttct tggtttctgg cgtttcaatc
    31621 aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt tgacataaga ctcaatggcc
    31681 ttgttttcgg tgattttttt gatgtcttca cccttgatat tcccagcacc acgaggcgtt
    31741 ccttggttga cgcgacgatt gatttgcatg gagaagctat tggtgatatt tttaaaggtc
    31801 tcctgagaag ccttggcagt agctcccttg attgacaagc cgaccaaact caagctcgcc
    31861 atgaggagaa taatcaggaa gatgacaatc gatttgaaaa acttccttgt aacataggca
    31921 aatgcgttgt gtaacataga ttccctttct agattttgtt ttaatcattc tattaaaata
    31981 agctcaaatt atttactagt attgcgcgtt tcagtcagtt tcttatcctt taattcaagt
    32041 gtaatatctg acgcttgtgc cacttcttta ctgtgagtta cgacaatcac acatttacct
    32101 gttttctggg caagtgattt gagtagttcg acaatatctc cagcagtttt aggatccaga
    32161 tttcctgttg gctcatcagc tagaataact ggagcttctg agaccaaact gcgagcaatg
    32221 gcaacacgtt gctgttgacc acctgataac tggagaacat tccgcttgat ctggctttca
    32281 tccaaaccaa gctcaagaag tgtattcttg cttgcctttt tgttgaccaa tcggatattt
    32341 tccagcggag aaagataatc tatcaagtta taattttgaa agaccaggga aatatggtgc
    32401 atgcgatggt aagaatagcc cttcttacga atatcctctc cttgaaaaag gatagaacct
    32461 tcaacaggac tatctagacc agcaagtagg gacaagagtg tggattttcc tgctcctgac
    32521 tccccaataa tactgtaaaa ttttccgggt tcaaaattat aattgatctg atataggact
    32581 gcttcagcag tattcttata acggtaggta acatcttgta attgtaataa agtcatgatt
    32641 tctccttctt aactaataga tgataaaatt tctttcggtg attttctaaa taagaatagg
    32701 aaacaaaggg ctacagataa gcaactaagc agaactagaa aaacatagga ttctgcaaaa
    32761 gataagatgc tagttgataa actgcttgct ttggctagtg tatcttgtaa gcttgcctga
    32821 tctccacttg ctagtagagt ttggagtagg taagttgtga ttgcgtttcc tgcaacaaat
    32881 gctggaagca aagctccaag agataccaaa actacctcta aacagaattg taggaagatc
    32941 gagctcttgc cttttccaag tgcaagtaaa atccccactt catagacccg ttctctcaac
    33001 cagagagaca aaaccagaat taaggctcca gctcctgcta tcaacatccc ataaaggaag
    33061 atggtcagga aggtttggaa agttgcaact gagtctttga tttgttcaaa agccttgttt
    33121 tccttttcga cttggtagcc ttgattttcc aaggccaagt tttctacctg cttcatgagt
    33181 ccgtccattt ccttaggatt ttctacatag aagcgtgctg cactgacttg agcttcacta
    33241 ttgcccaaaa gggtttggct actttcatag tctgtaaaga cttgattttc actgaagtca
    33301 gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa agatgccgat aatctcaaac
    33361 tctactgttt gtccttttcc agattcagac tgaccagcat ccaagccaat cttgtcatga
    33421 agcgaaagac cgttcttctt agccaattct tcgtggataa ggattttctt ggaatcccct
    33481 ttttgaaggt gtcgcccttc ttttagattg aaagccgaac tggtaaaggt tacatccttg
    33541 gatgaatcct caagagccgt taagctaacc aagttattgt ctgcagctga taaatcatca
    33601 cgctccacgc tctgctcgcc agtcactgct tccttgtctt ttagttttgc gaccgtctca
    33661 agttcaggag agacattttc cagcccctta atcttgctta cagatgctag gtctgacaac
    33721 ttgaatgtct gaccattctc tatcttctta atagaaaaag atgtattgag tgatttataa
    33781 agattgcttt ctactgtttt gttggacttc atcagagtca aacaggctga aattccggcc
    33841 aataagacca ataaaatcag aaataaaata aaacttctca gtcgctttct gctgacataa
    33901 gcccaagatc tttggattgg attcatttgt cacctccata tttgtaagac tattataaaa
    33961 cccaaatatg aaatgtttat gaaatacgaa aaaaaaatat cgagtagggg ataatctcta
    34021 gcccctctca caccaccata cgtgccgttc ggcatacggc ggttcaacta acttttaacg
    34081 catgtcgttc aaggtaataa tccaaacacg aaaccagtcc acgtttttca aggactggtt
    34141 ttgatatagc acgtttaagt accgacttct gagctactat agtatattga aactagaata
    34201 gtacacctct acttctaaaa tattgttaga aatcgatttg actgtcctga acgattcgtc
    34261 ctattcttat ttcattttac tataattgat agtggtcgcc ccagccagat accttatctg
    34321 ctatccattt aggaacccct aacttaagca atccccataa tcgtctcgat ttcttcttcc
    34381 attgcttcca gataatcact cgtaggcgag tacgcaagcg ctcatctatg ctagtgacta
    34441 tacttttcat atttataatt cattcctttc gtttcactca aggcacaaca cagaatgaaa
    34501 aagtgttgtg atctttattt tgttttataa taatagtgag aaagcctatc actactacaa
    34561 atcacgggga ggtgaataag tgagtggtac agccactacc tcgcatattt tgtcacatca
    34621 tttaacggta cataataagt tgtaccatct gaataagttg ctacaatatc atttgcatgc
    34681 tctccttcac ctttagcaaa ggttggagct cctgctggat gatttttatt tgcctctttc
    34741 aatttttcaa taatggcatt ttttctgtat cttttatatt atcaggattt ttcactaaga
    34801 ttttgtctgg atatgtcggt ttagcagaaa caatttttac tgttatttct tttttattcg
    34861 aagcacttgt ccagtttcca gcattatctt tagcatttaa ttttacagta attcctgaac
    34921 taggaacttc agtagcaggt tgattatcaa cattattcaa ctttaatttc aaaagagctg
    34981 ttgcatcaga cgttttatca atcgttatat ataatgatga attgttatta taaccagttt
    35041 cttcatattt agctgtttgt gagctacttg aaacagaact gaaattatgc ccactacctc
    35101 cctgattatc ttcaatgctt acgtctaaat gaacttcccc actattattt ggcttagcaa
    35161 caactgttat agtaaaataa cataaaattt gcataaatag attaggtaaa tcaaagcaac
    35221 ttctaggaat gttttagcag tcacagtgta ctttcccagc atcaagccac tataactctg
    35281 cacataaaaa
//
LOCUS       DAVKUR010000017        35243 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKUR010000017 DAVKUR010000000
VERSION     DAVKUR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.017"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..684)
                     /locus_tag="VW749_000942"
     CDS             complement(34..684)
                     /locus_tag="VW749_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0174992.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            796..1638
                     /locus_tag="VW749_000943"
     CDS             796..1638
                     /locus_tag="VW749_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0174993.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            1714..2151
                     /locus_tag="VW749_000944"
     CDS             1714..2151
                     /locus_tag="VW749_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0174994.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            2220..2522
                     /locus_tag="VW749_000945"
     CDS             2220..2522
                     /locus_tag="VW749_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0174995.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(2613..3686)
                     /locus_tag="VW749_000946"
     CDS             complement(2613..3686)
                     /locus_tag="VW749_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0174996.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            3842..4519
                     /locus_tag="VW749_000947"
     CDS             3842..4519
                     /locus_tag="VW749_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0174997.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            4512..5486
                     /locus_tag="VW749_000948"
     CDS             4512..5486
                     /locus_tag="VW749_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0174998.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VW749_000949"
     CDS             complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VW749_000949"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0174999.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(7536..7859)
                     /locus_tag="VW749_000950"
     CDS             complement(7536..7859)
                     /locus_tag="VW749_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0175000.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            8718..9347
                     /locus_tag="VW749_000951"
     CDS             8718..9347
                     /locus_tag="VW749_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0175001.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            9488..9757
                     /gene="rpsO"
                     /locus_tag="VW749_000952"
     CDS             9488..9757
                     /gene="rpsO"
                     /locus_tag="VW749_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0175002.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            10572..11186
                     /locus_tag="VW749_000953"
     CDS             10572..11186
                     /locus_tag="VW749_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0175003.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(11479..12228)
                     /locus_tag="VW749_000954"
     CDS             complement(11479..12228)
                     /locus_tag="VW749_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0175004.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            12361..14697
                     /locus_tag="VW749_000955"
     CDS             12361..14697
                     /locus_tag="VW749_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0175005.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            complement(15134..18280)
                     /locus_tag="VW749_000956"
     CDS             complement(15134..18280)
                     /locus_tag="VW749_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEV0175006.1"
                     /translation="MIRTEVTSMTVPDRLPARMRMDGRSIFQQIKNYFDTENKEYFKH
                     PNTYDGISMHLEPNILTSMEHFDLTGFHCECKDFQNQGVCKHWVAMDLYFRSLPQAIQ
                     ERIGKASHKPSFASQLIPTLPSEELQDELVEEKATAPSLALHGQVEIRNHSLAWTLKL
                     QVEQAPRAYVIKDIAHFIFLIFQKEDYFVSQKIGTIRLSLNQFNQASQNLLLYIKKYF
                     IDRNEHSYFNFSYGINPRDYGRYLETPVSYLNDLVPLFQALDVFQYVTSKAEYPLIFL
                     DDSPFIPEEEIFKVVKSNNHYEIINTAYFGFIIQEKLWIRHNHFHIIKEEHRYFLDKL
                     ATWIYHYQENSPLIFSKENKAELMQVCNIISNYVPISIPDELQIHDFIPTFAFSKTRN
                     EIALNMVWSFGEKQVHSKQDLLTLPYTYQASKARKIYHQLLSAGFKEEFHSLSKIKIV
                     DFFLKELPRFRTLGQVQLDESLEKLLVEDPAVIDIFDDESFLSVQFDFSMISEDEVEK
                     AIQALWNQESHYQTKQGKVLVFDDESLKVAQSLQDLRAKFSDGKIKMHKSRAFSLSET
                     FKDNEHVNFSRDFKKMAYDLTHPEEFDIKPYEVKAKLRSYQKEGVKWLSMLDHYHFGG
                     ILADDMGLGKTLQTITLLEANLKPDQKALILAPASLLYNWKEEFRKFVPHKQVEVAYG
                     SKTERIKQIEKSATITITSYPSFRSDLEHYQKQSYDYLILDEAQMIKNSQTKTAQALR
                     EFDVKTCYALSGTPIENRLEEIWSIFQIVLPGLLPSKKEFSKLSPQLVAKLIQPFVLR
                     RKKDEVLTELPELSEHLYSNELSSSQKTLYLAQLRRMQEMVSGASAYEIKRHKIEILA
                     GLTRLRQICNTPALFLEDYKGDSGKMDSLFELLDTIREKGSRPLIFSQFTSMLDLIEQ
                     ELEKKEMSHFKITGQTPSDKRQEMVNLFNQGEKDCFLISLKAGGTGLNLTGADTVILC
                     DLWWNPAVEMQAIGRSHRLGQTKQVDVYRLITLGTIEEKIQELQESKKELFNTVLEGQ
                     ESRSNLSVDDIKEILGVE"
     gene            complement(18469..19707)
                     /locus_tag="VW749_000957"
     CDS             complement(18469..19707)
                     /locus_tag="VW749_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175007.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYAFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLMMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIDFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            complement(19709..21145)
                     /locus_tag="VW749_000958"
     CDS             complement(19709..21145)
                     /locus_tag="VW749_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0175008.1"
                     /translation="MTPIKDKVRRVKTPMMVNPDTDLTISSVQQDYFSLALIGFSLLT
                     GDFLSFSKGDQKTGLSAFIKICHLIKIARLDNKITKQQEYWLYDLLMMSQGEKIQKIK
                     QLKQVTSDILLNTPDFSSYFEKYNFKEEAENIKSYLLAKSMDKSGRLFPSNEFGEFVS
                     PVSFQHGFGGVLFFMNKYYVEEDENTVKEWLTKLENYEAANFLHGYSLLFGKAGFLFG
                     ILDRYEKTKERYLIDISKRLVDHLMRVYDNISNLDFALGKSGILLSLMKYCTIFDDKK
                     LANFIKNNINDAYSLLESEDNGDIYSNNFAHGRSGAAYVLKAYTDIFGDSRYQNHLQK
                     FSDGISELLEEKLSSFSKLDNLGLSWCDGVSGLILYLCLIDKERYSEIIYKSQLEMVQ
                     QYEAMGTSFCHGLSSLLQTTIYNKNQKVEQFIKKILLTRSYRNNDRLLQFQGEDGINS
                     YFDFGVGNLGIYWTLLGYTFPFELSKGD"
     gene            complement(21219..21749)
                     /locus_tag="VW749_000959"
     CDS             complement(21219..21749)
                     /locus_tag="VW749_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV0175009.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSYIHKLGI"
     gene            complement(21743..22211)
                     /locus_tag="VW749_000960"
                     /pseudo
     CDS             complement(21743..22211)
                     /locus_tag="VW749_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22760..23437
                     /locus_tag="VW749_000961"
     CDS             22760..23437
                     /locus_tag="VW749_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0175010.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLCKEVSPVFVQKWQKEAVKLEFALGQIPDKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23424..24221
                     /locus_tag="VW749_000962"
     CDS             23424..24221
                     /locus_tag="VW749_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0175011.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFGELAQHVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24238..25341
                     /locus_tag="VW749_000963"
     CDS             24238..25341
                     /locus_tag="VW749_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0175012.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25642..26661
                     /gene="galE"
                     /locus_tag="VW749_000964"
     CDS             25642..26661
                     /gene="galE"
                     /locus_tag="VW749_000964"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0175013.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26663..27598
                     /locus_tag="VW749_000965"
     CDS             26663..27598
                     /locus_tag="VW749_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0175014.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTNWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSYHRS"
     gene            27773..28417
                     /locus_tag="VW749_000966"
     CDS             27773..28417
                     /locus_tag="VW749_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175015.1"
                     /translation="MLSKEEYIEEIGLIEKQNYVEVELYPLVADIINPTLKNSLSKRY
                     VFGRRKSNMGQIYYGLSNFPDIVILDKNYQNKARKSIEIEEWKKLRGCVEIKSLKHDL
                     ITEEKIKSTISNSFEHITGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKEEIDNTIV
                     QVVNKRIETEEAGNSFDWWKNIKDLSFNYTDIYLSKDCIQEWDEFVKKVKEIEW"
     gene            28456..28557
                     /locus_tag="VW749_000967"
                     /pseudo
     CDS             28456..28557
                     /locus_tag="VW749_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(28608..28814)
                     /locus_tag="VW749_000968"
     CDS             complement(28608..28814)
                     /locus_tag="VW749_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0175016.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            28866..29342
                     /locus_tag="VW749_000969"
     CDS             28866..29342
                     /locus_tag="VW749_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0175017.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMVTGSWFANPGDVIKIK"
     gene            29351..30022
                     /locus_tag="VW749_000970"
     CDS             29351..30022
                     /locus_tag="VW749_000970"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0175018.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            30153..30491
                     /locus_tag="VW749_000971"
     CDS             30153..30491
                     /locus_tag="VW749_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0175019.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            30494..31123
                     /locus_tag="VW749_000972"
     CDS             30494..31123
                     /locus_tag="VW749_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0175020.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            31363..32514
                     /locus_tag="VW749_000973"
     CDS             31363..32514
                     /locus_tag="VW749_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0175021.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32827..33576
                     /gene="truA"
                     /locus_tag="VW749_000974"
     CDS             32827..33576
                     /gene="truA"
                     /locus_tag="VW749_000974"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0175022.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            33566..34339
                     /locus_tag="VW749_000975"
     CDS             33566..34339
                     /locus_tag="VW749_000975"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0175023.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            34317..34778
                     /locus_tag="VW749_000976"
     CDS             34317..34778
                     /locus_tag="VW749_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0175024.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     AIIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35005..>35243
                     /locus_tag="VW749_000977"
     CDS             35005..>35243
                     /locus_tag="VW749_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0175025.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKVLHEGWTKDRV"
BASE COUNT        10333 a         6386 c         7618 g        10906 t
ORIGIN      
        1 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
       61 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
      121 gctgaagcca tcaaactgct taacttggag ctggtcaccg atgtgaagtg agtgcttgtc
      181 cagataatgg agaatgtcaa aactatcgtg catccgagtc aggcggtagg cgccagcttc
      241 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
      301 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
      361 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
      421 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
      481 cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgagatt
      541 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
      601 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
      661 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
      721 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
      781 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
      841 gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata ctggcttttg
      901 ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt ggatcaacta
      961 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
     1021 gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca gtatgtttta
     1081 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
     1141 cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa ctgggggcga
     1201 gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca tcctccctgt
     1261 gatattgctg tttatggaca cattcaccag cagttgcttc gttacgggac tggtgggcaa
     1321 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
     1381 gacttgcggg cccagtatat gattttggag tttgatgaca agggcctggt agatatggac
     1441 ttccgacggg tagattacga tgtggcagct gaattgcagc tggctaaaga cctgagactt
     1501 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
     1561 gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga cgactggttg
     1621 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
     1681 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
     1741 gcaactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
     1801 tttctggctg ctagtgttgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
     1861 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
     1921 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
     1981 caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
     2041 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcag
     2101 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
     2161 atgccctctt tttttctttg gataattatg ataaaatgta gctattaaag gagtaagaaa
     2221 tgtatctcgt tatagaaatt gtattagcct ttatagtgtc attttggaag gataatagaa
     2281 gtttgtggaa tccagtatta tttttattat ccctcatttc aagttatttt tatctatcct
     2341 acctttttta taaaaatgga tacgagaatg ttcagttagc tttttatgta tttgcctttg
     2401 tcttacttcc ttttttgctt tttctaagtg gcatcttttt aatctataat ggggtcattt
     2461 tgttgaaacg agagggacgt tccaagcccc attatctctc aatgctcttt gatttttatt
     2521 gactattaga ttctatttaa aaagacttag aatgaacatg aaagtatgta ttctaggtct
     2581 tttgttttgt atacatttaa ttttcaagag tattatctat ttttccatgc atggtaacga
     2641 gtatcaatca ataactgggt aaggcgaccc aaggtttctc tttcttctgg agtgagggat
     2701 tgagcttgga caaagagatg atgaatgtat tcaagcgcct ttaaggaagc caagtcattg
     2761 atagagctaa taccagcatc aagaatagtg ccaaagaaga ggtcgaagta gagctgaagt
     2821 tcttcgtcag ggactgtggc cacccattct ttaaaggttg tgtctacttg ccggctatca
     2881 ctgttggtct tatccagttg aacgaagtgc ttgtcctcaa tctgccaact aaaggtatcg
     2941 tgctgggcga tgccacccag ggcagtactc tgaacgatga tttggtgagc aggaatttcc
     3001 agcatcatac cgataatgga accttgtgga atgaatatct tgcttctatc cattatcctt
     3061 tgataacccg cagtctgtgt caattcttga tggagaccag gtgcatcaaa tgtataaact
     3121 gctgtgatct gattttgcaa actttgctca atttggctag cagcatagat agcgagattt
     3181 cctcccttgg aatgcccagc cagaataacc ttttgcttag gatgatgggc aaaaaagttc
     3241 tttaaatagc gaagggcgtg cttttgagca ggaatttcct tcatataggt caggtggaaa
     3301 tcttccttcc agccaatgat actgtcatct gtcccacgaa agacaatcag ataggtatcg
     3361 aggctgacac gataagtcat agccgcaaat tgcttttgca gttcagggtc gatgtcgttg
     3421 ataaaatggg agagtttgca atttttgaag cgcttgtgtt gagccaattc atctaataat
     3481 tgaaggcgat ttttgctagt aagcatggtg ggctctcttg gaacctgagg tgctagatct
     3541 aaaagacgtt gaggaagtgt ggagaccaga ttatcaaagg agaggtaggt gatttctatt
     3601 aaggttagaa tgtctaactc attcaaggga aggtcgtaat aagaatcata tgcgacatct
     3661 ttcagatagt caaaaatatt ggccataaga gctcctttct ttttatttat cttagcaaat
     3721 ttccctcaaa ttagctagta gcatagcctg tttgtactgg ctaaaaacag gctatttcaa
     3781 attcagtttc agaccatcta gcatggaaaa atctgttata ataatggaaa aggagaagcg
     3841 catgcacaag attttattaa tagaagatga tcaggtcatt cgtcaacaga ttgggaaaat
     3901 gctctctgaa tggggatttg aagtggtcct ggtagaagac tttatggaag ttttgagtct
     3961 atttgttcag tcggaacctc atctggtcct catggatatt ggtttgccct tgtttaatgg
     4021 ttatcactgg tgtcaggaaa tccgcaagat ttccaaggta cctatcatgt ttctttcttc
     4081 gagagaccag gctatggata ttgtcatggc aatcaatatg ggggcggatg actttgtgac
     4141 caagcctttt gaccagcagg ttcttttagc taaggttcag ggcttgttgc gtcgttccta
     4201 tgagtttggg cgtgatgaga gtttgctgga atatgctggt gttatcctca ataccaaatc
     4261 catggattta cattatcaag ggcaagtctt gaatttgacc aagaatgaat tccagatttt
     4321 acgcgtgtta tttgagcatg caggcaacat cgtagcacgt gacgacctga tgcgggaact
     4381 ttggaacagt gactttttca ttgatgataa taccctctct gtcaatgtgg ctcgtttgcg
     4441 taaaaagttg gaggagcagg gattggtagg atttatcgag accaagaaag gaatagggta
     4501 cggattgaag catgcttgat tggaaacaat tttttctagc ctatctgcgc tcccgtagtc
     4561 gtctttttat ctatctgctt tctttggcat ttcttgtctt actctttcag tttttatttg
     4621 ccagtctagg aatttacttc ctctactttt tcttcttgtg ttgctttgta accatattat
     4681 ttttcacttg ggacatattg gtggaaacgc aggtctatcg ccaggaactt ctctatggag
     4741 agagggaagc caagtctcct ttggaaatag ctttagcaga aaaattagaa gcgcgtgaga
     4801 tggaactcta tcagcagagg tcaaaagcag aaagaaaact gacggatttg ctggattact
     4861 ataccttgtg ggtccatcag ataaagaccc ccattgcagc cagtcaactc ttagttgcag
     4921 aagtggtcga ccgccaactg aagcagcaac tagaacagga aattttcaaa atcgactcct
     4981 ataccaacct agttttacag tacctgcgtt tagaaagttt ccatgatgat ttggtcttaa
     5041 agcaggttca aattgaggac ttggtcaagg aaataattcg taaatatgct cttttcttta
     5101 ttcaaaaagg cttaaatgtc aatctacatg accttgataa agaaatcgtg acggataaaa
     5161 agtggctgct agtggttatt gagcaaatca tctcaaacag tctcaagtac accaaggaag
     5221 gtggtctgga gatttatatg gatgaccaag agctttgtat caaagatacg ggaatcggga
     5281 taaaaaacag tgatgtcctc cgagtatttg aacgtggctt ttcaggatac aatggccgtt
     5341 tgacccagca gtcctctgga cttggccttt atctatctaa gaaaatttct gaagaactgg
     5401 ggcaccagat tcgtatcgag tctgaggtcg gaaaaggaac gacagtgcgg attcagtttg
     5461 ctcaagtgaa cttagtcctt gagtaaaaat agatgagaaa aagcctccag attggaggct
     5521 tttatgctag actcttattt ctcaacgcgt gatttgttgg cgatatcagc taggatagct
     5581 tgaacaaaat tatcaactga gacagtttgt gtttcttttt ggccgtagcg acgaacgttg
     5641 actgtttcgt cttccatttc tttgtctcca acaattaatt ggtaaggaat cttgctggtt
     5701 tgtgaagcac gaatcttgaa ctgcattttt tcattgcgct catctacgtc tgcacggaca
     5761 ccgcggtcac ggagtttctt ggccacttcc caagcgtagt ccacgtgttt ttcgttagat
     5821 actgggatga gggttacttg gtgtggtgcc agccatgttg ggaaggcccc cttgtagttc
     5881 tcaatcaaga tagctgtgaa gcgttccata gttgagataa ccccacggtg gatcatgact
     5941 ggacggtgat cttcgccatc agctccgatg tatttgaggt cgaagcgttc tggcaacaag
     6001 aaatcaagtt ggatagtaga aagggtttct tcttttccaa gggcagtttt aatctggata
     6061 tccaattttg gtccgtagaa ggctgcttca ccttcggctt caaagtagtc cacgcccatt
     6121 tcatcaagag ctgcacgaag catggtttgg gcattttccc acatctcatc gttatcaaag
     6181 tacttatgag tatcttgagg gtcacgaaga gagaggcgga agcggtagtc agtcaagttg
     6241 aagtcttcat aaacatcgat aatcaactga agggcacgtt ggaattcttc ttggatttgt
     6301 tctggagtaa cgaataggtg accgtcgttg agtgacattt cacgtacacg ttgaaggcca
     6361 gtgagggcac cagatttttc gtaacggtgc atcataccga tttcagcgat acggattggc
     6421 aattcacggt aagagtgaac atggtgtttg aaaacttgga tgtggtgcgg acagttcatt
     6481 ggacgaagga caaattcttc cccgtcaccc atgtccatgg ttgggaacat gtcttcttgg
     6541 taatgatccc agtgaccaga agtcttgtaa agctcaacag aagcaagtgg tggagtgtag
     6601 acgtgttggt agccagaagc caactctttg tttacgatgt agcgttccaa ttcacgacgg
     6661 atagtcgcac catttggcaa ccagaatggc aaaccttgtc ccacttcttg tgaaatcata
     6721 aagaggtcaa gctctttacc aagtttacgg tggtcacgtt ccttagcttc ttcacgcatt
     6781 tgaaggtagt ttttcaagtc tttcttgtca aaccaagctg taccgtagat acgttgcatc
     6841 atagcgttgt cgctgtttcc acgccagtac gcaccagcta catggagaag gtggaagatt
     6901 tggatacgac ctgttgatgg aacgtgaggt ccacggcaga ggtctacata ttcaccctga
     6961 cgatagatag tcaaaccgcc ttcgtcttct gagtgttctt caatcaattc caacttgtaa
     7021 gggtcatttt tgaagatttc acgtgcctcg tctttagtca cttcttcacg aatagatggg
     7081 aagttttctt tgacgatttt ttgcatttct tcttcgatac gaggaaggtc ttcgttagag
     7141 atttgaccag ctgtgttgtc agtatcgtag tagaaaccat cttcgatggc tggaccaact
     7201 cccaagtgaa tgtctgggaa aagacgacga gctgcttggg cgaacaagtg agctgctgag
     7261 tgacgcaaga ttggaagggc atcttcgtga tcaggtgtca caatttcgat gcttccatct
     7321 tcagtgatag cgcgagtagt gtcgatgagt ttgccgttga atttaccagc caaggctttt
     7381 ttagctaggg aattgctgat agattgggca atttcaaaag ttgttacgcc agattcgaat
     7441 tcacgaacag cgccatctgg gaaagtaatg ttaatcatga tgttctcctt ttttattatt
     7501 tcatagtttc taagcattga ttttttatca gcagactact tccaagtcct aacgttcaat
     7561 tgcttttctt tatcagagag gaagttttcc atttccgtca gaatgtctat atccaaacgt
     7621 tgagaaagtt ctaatagcca ccagatattt tctgaaagtt tttgttccag tgtgtagggt
     7681 gtttcatcat agtagcgtcc ttgctttgtc atcaccagtc gttggaaatt tccaatatca
     7741 ttagataaag ccaagaggtc ttcttctacc gtccacttga aatcatgatg cttaacttcc
     7801 agttcgtgat aagcttgtcg gattgcccaa ctgcgctcca ctaattcttg caactccata
     7861 attagtatcc taataaaaaa atgcgacatc ctcgaaagga cgtcgcaacg tggttccacc
     7921 ttcatttatg tacctcaaaa gagagggaca cctctgatcg gctctaacgt ggccaccgtt
     7981 ttatgttttc ataaaaaact caagagtagt atcagtttag acttcctatg cgtttccagc
     8041 aaccacgcac tctctagtag aaagggacta agtgacttgt ctctatggat tattatagca
     8101 tgattgtgag atttttcaag gattttgtga aagttttttg tttttcatat tttgtagaat
     8161 atgcttgatg ctaataccag aatccatgcc caccagagca actgtttcat agattagcaa
     8221 gtaaattagt ataaactcac caaaggttat gatagtaaag taaaagagca gtccgttacc
     8281 aactaaccat caaagtgaga aacggaaacg gtagctatag agtaacgata caatcaagat
     8341 taccagaggt gtaaagaaga gaagattgtt tatatagtgt aaaggggtca gaaacaacta
     8401 gcaagaacaa ctcataaagt ggccaataaa agaataatat gaccagatag taggggagat
     8461 gggaatagaa tctacgcatg ataatcacct cgttttaaaa aaacagacaa cttagatctc
     8521 ttgctatgat tattatagca tgtttaaaac aagaaagtaa atttgttgac aaagaagatt
     8581 tttcttttca ctagaatcat agttagtttt cttggtagaa atattttgat aataattaag
     8641 caagactatt gatattgatt attaagagtg tcacatttgt tgtaactaaa ataattacaa
     8701 caatagaggt ataaaaaatg aaactagcag ttattgcagc aaatggacaa gcggggaaag
     8761 caattgttga agaagcagtc aaacgaggac atgaagtaac ggctattgtt cgttctgaaa
     8821 acaaaagtca agctgagtct attattaaaa aagatttatt tgagttgaca aaagatgatc
     8881 ttactggatt tgatgctgtt atttcagcgt ttggtgctta tacaccagat acgctaccgc
     8941 tccacagcaa atcaatcgaa ctatttaatc agcttcttgc tggaacacag acacgttttc
     9001 tagttgtagg gggagcagga agtctttata tagatgaaac aaaaacgaca cgacttttag
     9061 atacgtctga ttttcctgaa gaatttaagt cactagcaaa agctcaagcg gatgaatttg
     9121 atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct gtagatttta
     9181 ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt actactaatg
     9241 gaaaaggaat aagccagatt agttatgcag attatgctat tggattggta gatgaacttg
     9301 aaaaaggtca tcatataaaa gaacgtatct ctttacttga aaaataataa ctatgagagt
     9361 attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta aagacaaata
     9421 acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa taaaaaggag
     9481 aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat atgcacgtca
     9541 cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg aaatcaacca
     9601 ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg gattgatgaa
     9661 aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg ttaaccgtta
     9721 ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa ggccgtcaaa
     9781 agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga gattttatct
     9841 tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataataa agctactcta
     9901 aattgggtag ctttgttgcg ttgtcacctt acctcgctat actcaagtat aatcttcggt
     9961 tacggttcct agcactgtaa ggtaaaataa actagctttt ctcccttcgt ggagattttt
    10021 ttgtttcact gaaagtttcg tacgatcttc acctcgtccc ctagtctata aacgatttat
    10081 ctagcaagaa tcatgatgct aagggtgtca aaaatccgta tgaaaatagg gaaatgacac
    10141 agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc cgggctaaaa
    10201 tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca attttggaga
    10261 ctacaaaaat ctcaaatggt atcagctaat tacaccataa aggtgcgcag ctactcggct
    10321 tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta caaagtaaag
    10381 tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa attactttgt
    10441 aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc actagcgata
    10501 gctaaattaa tgtgtttgtg ctctcctaaa atctgctgat ttattactga ctaatacagg
    10561 aggttttttt tatgggacag acaatcatat ctgctattgg tgtttatatt tccaccagta
    10621 tcgattattt aattatttta attattttat ttgcacagct atcacagaat aaacagaaat
    10681 ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg agtttagttg
    10741 ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt ggtttaatcc
    10801 ctatctattt agggattcgc tttgcaattg ttggagaaga tgcggaagaa gaagaggaag
    10861 aaattattca aagattagaa caaagcaagg caaatcaact gttttggaca gttacattgc
    10921 tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt gcttcgttag
    10981 attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt atcttttgcg
    11041 agattagtag ggtgttatcc tctattccgt taatattcga gacaattgaa aaatacgagc
    11101 gaatcattgt gcccttagta ttcattctac ttggactata catcatgtat gaaaatggca
    11161 cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt agcctgagct
    11221 caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga caatcttaaa
    11281 gttactctat tgtagagtgg cttttgattt gattagggga ttcttataaa tatagtaaaa
    11341 tgaaataaga ataggacaaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    11401 gaagtagagg tgtactattc tagttccaat ctactatata aatgaaaacc ttagctgttt
    11461 ggccaaggtt catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa
    11521 gcttgcgata aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc
    11581 agggatgcgg ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt
    11641 ttcttcgtcc agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc
    11701 atcattcatt ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg
    11761 ttcacggcta atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg
    11821 gaccttggcc attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct
    11881 accacttgga aacatgatga gagagcggtc actttttttg agaacgttga taggatattt
    11941 gatggctgag gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca
    12001 ccaaccaaag atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg
    12061 cttggtcgca aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat
    12121 ataattttca tcttgattag gaattttatc agtattatga tagtgagcat tgccattgat
    12181 ggaccataag agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc
    12241 gattgttttc ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga
    12301 ctagatgcat atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt
    12361 atggataaaa ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag
    12421 ggtttggtca atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga
    12481 aatgtcttta ccctttttaa cgctttgaac tttgccattg ctttggccct tgcctttgtg
    12541 caggcttgga gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt
    12601 gtgaccgagc tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag
    12661 gtcaaaacca tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga
    12721 gatgtcattc gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc
    12781 tttgcggaag tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt
    12841 gacggcttac ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac
    12901 catgtcggtg cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc
    12961 atcaactccc gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc
    13021 attccctttg gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag
    13081 tcatctgttg taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt
    13141 ttgaccatta cttcgctctt gactgcagtg attaagctag gtttgaaaaa ggtcttggtg
    13201 caggagatgt actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg
    13261 ggcaccatca cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac
    13321 ggtgaagagg ctattgccag catcttgact agctacatgg cccatagtga ggataagaat
    13381 ccaactgccc aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc
    13441 aatcttccct tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca
    13501 gttttcttag gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc
    13561 ttggagagag gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac
    13621 aaaccacaga aaccatctga tattcaggct ctagccttgc tggaaatctt ggaccccatt
    13681 cgagagggag cagcagagac gctggactat ctccgttctc aggaggtggg actcaagatt
    13741 atctctggtg acaatccagt tacggtgtcc agcattgccc agaaggctgg ttttgcggac
    13801 tatcacagct atgtagattg ctcaaaaatc accgatgagg aattgatggc catggcggag
    13861 gagacagcta ttttcggacg tgtttcccct catcaaaaga aactcatcat ccaaacgttg
    13921 aaaaaagcgg gtcatacaac ggctatgaca ggggacgggg ttaatgatat cttggccctt
    13981 cgtgaggcgg attgttctat cgtgatggcg gagggggatc cagcaacccg tcagattgcc
    14041 aatctggttc tcttgaactc agactttaat gatgttcctg agattctctt cgagggtcgt
    14101 cgcgtggtca ataacattgc ccacatcgcc ccgattttct tgataaagac catctattcc
    14161 ttcctgttag cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg
    14221 atttttccct tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca
    14281 ccattcgttc tgacttttga gcgaaatatc aaacctgtcg agccaaactt cctcagaaga
    14341 tccatgcttc gtgccctacc aagtgccctc atggtcgtgt ttggcgttct ttttgtgaaa
    14401 atctttggaa cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc
    14461 ttggggtcaa ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga
    14521 gtcctattga ttgtctggtc agtaggaggc ttcctagcca cagctctctt cccaagaatt
    14581 caaaaactgc ttgaaattgc aaccttaaca ggacaaacat tacctgttta tggtgtcatg
    14641 atgttggtct ttacagtgat tttcatcctg actagtcgct atcaagctag aaaataaaga
    14701 aagactgcaa tctgtggatt gcagtttttt atacgatgga tctatcgtag atctgatgtg
    14761 caaggcctac gtgtctatta tctatcggtg aacccaagag tgattctcaa gcctgcttgg
    14821 attgaggtaa tagattcaaa tatctgtagt tagactattt gaagtctgat gcaagaaata
    14881 attctcttcg aaaatatctt caaaccaggt ccgttctatc cacaatctca aagcggtact
    14941 ttgagcaact tgtggtcagc tccctagttt gatagtataa aaactgtcag ataaaggggt
    15001 ggcgaaattg tatctaaacg aacagaaacg tgatggtaag gcgtatagag ctcataggat
    15061 ggcaaggaaa gtctagaacc taaaaaagaa ctagataaat ccactaagtg tggttactct
    15121 agttcttttt cgtttattca acacccaaga tttctttaat atcatcaacg ctcagattgc
    15181 ttctgctttc ttgtccttca aggacggtgt tgaagagttc ctttttactt tcttggagtt
    15241 cttgtatttt ttcctctatg gtaccaagtg tgataaggcg atagacatcg acttgtttgg
    15301 tctggccaag gcggtggctt cggccgatgg cttgcatctc aactgctgga ttccaccaga
    15361 ggtcacagag gatgacggta tcagctcctg ttagattcag tcctgttcca cctgctttta
    15421 gggaaatgag gaagcagtct ttttcccctt gattgaaaag attgaccatt tcttgacgtt
    15481 tatctgaagg tgtttgtcct gttattttaa agtgagacat ttcttttttc tctagttctt
    15541 gctcaatgag atcaagcata gaggtgaatt gtgaaaagat aagtggtcgt gacccttttt
    15601 cacgaatggt gtctaggagc tcgaataagc tgtccatttt tccactatcc cctttgtagt
    15661 cttctaaaaa gagagcaggg gtattacaga tttgtctaag tcgggtcagt cctgctaaga
    15721 tttcaatttt atgacgttta atctcatagg cgctggctcc tgaaaccatt tcttgcatgc
    15781 gtcgaagttg agctagatag agcgtttttt gcgaactgct gagttcattg ctgtagaggt
    15841 gctcgctcag ttcaggcaat tctgtcagaa cttcgtcttt tttcctacgc agaacaaaag
    15901 gttgaatcag tttagcaacg agttgaggtg acaattttga aaattccttt ttacttggta
    15961 ggagacctgg taatactatc tggaaaatag accaaatctc ttcgagacgg ttttcaatag
    16021 gagttccaga tagggcatag caggttttga catcaaattc tcttaaagct tgtgctgttt
    16081 tggtctgact attttttatc atctgtgctt catctaggat gaggtagtcg taagactgct
    16141 tttgataatg ttcaaggtca gatcgaaaag atggatagct tgtaatagtg atagtagcag
    16201 atttttcaat ttgtttgata cgctcagttt tgctaccata ggctacttca acctgtttgt
    16261 gaggcacaaa ttttcggaat tcttccttcc aattataaag aaggctggct ggagctagga
    16321 taagagcttt ctggtctggt ttaaggttgg cttccagaag agtgatggtt tgcaaggttt
    16381 tccctagacc catgtcgtct gccaggattc ccccaaaatg ataatgatcc agcatactca
    16441 gccacttgac tccttctttt tgataggagc ggagtttggc cttgacttca taaggcttga
    16501 tatcaaattc ttcagggtgg gtcaggtcat aagccatctt tttgaaatca cgagaaaaat
    16561 tgacatgttc attgtctttg aaggtttcag aaaggctaaa ggcacgagat ttgtgcatct
    16621 tgatttttcc gtctgaaaat ttagcgcgaa gatcttggag actttgagca accttgagac
    16681 tttcatcgtc aaagactaga acctttcctt gcttggtttg gtagtggctt tcttgattcc
    16741 ataaagcttg gatagctttt tcaacctcat cttctgaaat catagaaaaa tcaaactgaa
    16801 ctgaaaggaa gctttcgtcg tcaaaaatgt caatgacagc aggatcttct actaagagtt
    16861 tttcaagcga ttcatctagt tgaacttgac ccagagtacg aaaacggggg agttctttta
    16921 ggaagaaatc aacgattttg attttggaaa gactatgaaa ttcctctttg aaaccagcag
    16981 aaagcagttg atgatagatt tttctagctt tgctagcttg gtaagtatag gggagggtta
    17041 ggagatcttg tttagaatgg acttgttttt ctccaaagga ccacaccata ttaagggcaa
    17101 tttcatttct agtcttggag aaggcaaagg tggggataaa gtcatggatt tgtaattcat
    17161 ctgggatact gataggaaca tagtttgaga tgatattaca gacttgcatg agttcagcct
    17221 tattttcttt tgaaaagata agaggagaat tttcttgata atgatagatc caagtagcta
    17281 atttatccaa aaagtaacgg tgttcttctt tgatgatgtg gaagtgattg tgtcgaatcc
    17341 aaagtttttc ttgaataatg aaaccaaaat aagctgtatt gatgatttca taatggttat
    17401 tagatttgac aactttaaaa atttcctctt ccgggataaa gggactatca tctaagaata
    17461 taagagggta ttcggctttt gaggttacat attggaagac atccaaagct tgaaaaagtg
    17521 ggacgaggtc gtttaaatag ctaacaggag tctctaaata gcgtccgtaa tctctagggt
    17581 taatgccata actgaagttg aaataagaat gttcatttct atcgataaaa tattttttaa
    17641 tatagaggag taggttttgg gatgcttgat taaactgatt caaggataat ctgattgtcc
    17701 cgattttctg tgaaacaaag taatcttcct tttggaaaat gagaaaaatg aagtgagcta
    17761 tatccttgat aacataggca cgaggagctt gttctacctg taattttaag gtccaggcta
    17821 ggctatgatt tcggatttcg acttgtccat gaagggcaag tgaaggcgcc gtagcttttt
    17881 cttctaccag ttcatcttgg agctcttcag atggcaaggt aggaatcagt tggctggcaa
    17941 aacttggttt atgactcgct ttaccaatgc gttcttgaat agcttggggg agactacgaa
    18001 aataaagatc catggcaacc cagtgtttac agactccctg attttggaaa tccttacatt
    18061 cgcaatgaaa gccagtcaaa tcgaagtgct ccatactggt caggatgttg ggctccagat
    18121 gcatggaaat accatcatag gtattggggt gcttaaaata ttccttattt tcagtatcaa
    18181 aatagttttt tatctgttgg aaaatagagc ggccatccat tctcatacga gcaggtagtc
    18241 tatcgggaac cgtcattgaa gtaacctctg ttctaatcat tcttttctct atcttatcag
    18301 aatttatagg aaaagaatag atttatctta cataaattgc atcttgatag ggattggaaa
    18361 catttgtagt tgcaagatag ttgtatgtaa tatcgacaat caattacaag gagattacga
    18421 ttccatagaa actatcaagt gaaaactgac ttatccataa cattctagct aaacttcttc
    18481 ttggtttggt aagtttttca tctggtgaac tagataggct gctataagta gtaaaattat
    18541 aagagcaaaa gcaacaactt ccagaccagc acttgttgca agaaatacga gagcaaggga
    18601 taggacagct gggataagta agttgataac attgatggat gattgaactg atcccattaa
    18661 ctcctcagga atgattccaa aaatcatggc ttgcaagcga ggactcaata ctcctgccga
    18721 gaaagcatca cccgcacttc ctagtaaaat aagtaaaaaa cttccacgta gaaaatctat
    18781 aacaatgaga gactccatca atagactcca ataaatattc aggcgaatag aaattttttt
    18841 agatagaaat ccactcagaa gtccacctaa aataacatga agaaggctta tcattattaa
    18901 aattgccaga ctttgccctg ttgacaaacc cataaaagga tggtgaatca gtagaatcgc
    18961 actgacaggc tctaccatca tcaaaacagc ttgactaatg gacaaaatcc aaagcaagac
    19021 catgacatct tccatagtca tcaataattt cattgactct ttcaaatgct ggaaaaagct
    19081 actcattcct acataaggag gaacttcgat tttttcttcc tcttttttca agcggtttcg
    19141 gataagtaga cttcctagaa aggcaaataa aaaggttaaa acatttacaa aagctagagt
    19201 agaaatgcta aacagtccta aaaatactcc tccgctgaga ttacctatca aacgtacaat
    19261 ggaactcgtg gactgcctaa aacccatagc ctccgtcata tcatcgttta ttagtcgtat
    19321 gtaaatcggt gtcagcatgt atcctgcaag aaaaccaatc gtatctgaaa tcaagttcat
    19381 gctgcaaata aagaaaacag aaaagagaga gaagtcggta cttgtcagga gcaaagtcac
    19441 tccagaataa aggaggacct tgataaagag gatagaaata tacttgctga ttcgattttt
    19501 ttgaaaatca gctataactc cagtaaaaag ttgcaagacc tgtggaatgg tttctgatag
    19561 gctaatcaaa aatatagcta agggagcaaa ggcataagaa gagacataat tgataaaagc
    19621 taagtaaaaa atagtatctc caaaacttga aatccactca tttactgtta gctgacgaaa
    19681 agctcgattt ttaagaaaaa tatgcatatt aatctccttt acttaattca aatgggaatg
    19741 tataaccgag taaagtccaa taaataccca gatttcccac accaaagtca aaataactgt
    19801 ttattccatc ttccccttga aattgtaata atctatcatt attacgataa gaacgagtca
    19861 ataagatttt ttttatgaac tgttcaacct tttgattttt attgtatatt gttgtttgca
    19921 ataaactact taaaccatgg caaaaactag ttcccattgc ttcatattgt tgcaccattt
    19981 caagttgtga tttatagatt atctcagagt atctttcttt atcaatcaaa caaagataca
    20041 atattaatcc tgaaactccg tcacaccaag aaagacctaa attatctaat ttagaaaagc
    20101 ttgaaagttt ctcttctagt aattcagata tcccgtcaga aaatttttgt aaatgatttt
    20161 gatagcgact atctccaaaa atatcagtat aggcttttaa tacataggca gcacctgaac
    20221 gtccgtgagc aaaattatta gaatatatat ctccattatc ctcggattct aataaactat
    20281 atgcatcatt tatattgttc ttgataaaat ttgctagttt tttatcatca aaaatggtac
    20341 aatatttcat caaactgagt aggataccag acttccctaa agcaaaatct aagttactaa
    20401 tattgtcata aacccgcatt aaatgatcga ctaatctctt acttatgtct attaaatatc
    20461 tctcctttgt tttttcatac ctatctagga ttccaaatag gaaacctgct ttcccaaata
    20521 gtagagagta accatgtaaa aaattagctg cttcataatt ttctaatttc gtaagccatt
    20581 ctttaacggt attttcatct tcctcaacat aatatttatt cataaaaaat aaaactcctc
    20641 caaaaccatg ttggaaagaa acaggactta cgaactcacc aaattcattt gacggaaaca
    20701 aacgaccaga tttgtccata gatttagcca gtaagtatga ttttatattc tcagcctcct
    20761 ctttaaaatt atatttttca aaataacttg aaaaatctgg agtatttaaa agaatgtcac
    20821 ttgtaacttg tttcaattgc tttatttttt ggattttttc tccctggctc atcattaata
    20881 aatcgtatag ccagtattct tgttgtttag ttattttatt gtctaatcta gctattttta
    20941 ttagatgaca tatttttata aaggccgata atcctgtttt ttgatcacct tttgaaaagg
    21001 ataaaaaatc acctgttaat aaagaaaatc caattagtgc taaactaaaa taatcttgtt
    21061 gaactgagct gatagttagg tcagtatctg gattaaccat cattggtgtt ttaactcgtc
    21121 ttaccttatc cttgatagga gtcattgtct ccaagtctat taatgttata tcaccttttt
    21181 tggtatatat aaaatttgta ggagctatat ctacaatttt atattcccag tttatggatg
    21241 taacttacta tattcacaat gttatccagt gttttttctc taatatttaa ggagtgttct
    21301 gtttctcgaa taaattcttc aaagtttaac ccgtcaactt gttcctgaac aagaaaataa
    21361 tcatccacga tataaaattc atcagttaaa ttagtagtat aacttttatc ggctaatttt
    21421 tttagcatgt gagcttcatt ttttatatca tcaagagctg tccattctcc ttcagcatca
    21481 taattcacaa aaggtcttga ctgcttgatg attacttttt gcccgtccga ttttctaatt
    21541 gcccgataaa catttccttt atttgatctc ttaataattt tttccatttt gtatttattt
    21601 attgcagagt ccttacttga aacttcacat gtggtttgaa aataaatcct tttttcttct
    21661 tctgaaaata aatccatttt ccagctagga agactaggga aattttgtct cttatcttct
    21721 acatagttct tccttttttc atctagcaat aaatagatga cttttttatt tttttcatca
    21781 taagcttgtt tttttaaaaa agccccatat ctataatgaa ctggagaatg cattccacat
    21841 tgatagtcag atagtatttt tggagcctta aattctgaca gtctattcgt aagattacaa
    21901 atcatactct tagcttcaga ttctgactta ggatatagag ttataaattt gttagcagta
    21961 gggctcattt ccctagggga attaattttt tttaattcct ctaaattttt aacaacttta
    22021 aagctacaat tatttagttg ggatagttta tacacaatct taaaaatatt tacagcgtct
    22081 tttatttggg agcttatgtg tattttccac ccttgtgcag gcatcttatc tgataaataa
    22141 tagtaattcc aaatatcacc ctgttggaaa tttttatcac attttaaaca ttctttctct
    22201 aataaatcca taacaaactc ctaattatta aaataggcta gagacacagc actagcctat
    22261 tccgtaagta aagctactta ttttatataa aatataacta gcgacctgta attaaacaag
    22321 taaaagaaca atacttaggg agacctgtga caatgatatc ttcctctgga agtagttcta
    22381 attcaaacaa tgtttgttcc atgactgtat cctcctgtta tgataaattc cagaaagcat
    22441 agagcaaatt cgtggttcgt ctgactaaat ttcttatctg aacaccacct tcaaatacaa
    22501 attttagtca aacttttatt ttttctaact ttctaattat attctaccat gtgtttttat
    22561 atgtcaagaa ttttctgaat aaactgttta ttttttattt tttgacattt ttgcaaattg
    22621 tttaaaatct ttcaattgga ttcacttatt actttaggac attgaaactt ctttcgccag
    22681 aggtgcttat attactggga agttgaagat tgaaatgtgg tataataaga ggtaatagag
    22741 ttttggaaag tgagagaaga tgatttcaaa gagattagaa ttggtagctt cctttgtgtc
    22801 acagggggct attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt
    22861 tgagagaggc caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc
    22921 tgcggttaaa aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa
    22981 tggcttggca gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg
    23041 tggtcgtttg attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg
    23101 tttgatcctc cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg
    23161 attccagatt gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt
    23221 ggtggaagca ggacaaatga agctatcagc cagtgatgtt cgctttggac cgttcttgtg
    23281 caaagaggtc agtccagtct ttgtccaaaa atggcaaaaa gaagctgtta agctagagtt
    23341 tgccctcgga caaatcccag acaaaaatct ggaagaacgt caagttctag tagataagat
    23401 tcaagccatc aaggaggtgc tccatgttag caagtgaagt gatccaagct tatgaagcct
    23461 tttgccctca ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag
    23521 acaagggtat ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg
    23581 ccattgaaaa gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca
    23641 aggacttgct tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgaca
    23701 tcgcagttta tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt
    23761 tttgtcagat gctagaaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg
    23821 gaattggacg tattgggaat attcagcctc agacctttgg agaattggcc caacatgtca
    23881 agcaagtctt tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga
    23941 agcctatttc aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt
    24001 tggcaaaggg ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata
    24061 tgctgtctga tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg
    24121 aaaaaatcgc agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt
    24181 tacctagtca agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg
    24241 aaaaaagttg ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg
    24301 agagaaagtg acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc
    24361 gcagcaggaa ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtacaagatg
    24421 gcgcgcttgg gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa
    24481 gaaatcgact tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaatttg
    24541 gaagaacttt atcaactggc cctccagcgc agagaagaat ctcccttgat agggcaatta
    24601 gccattctga accaagcctc agctaatgaa ttattccctg gtttgcaggg atttgaccgc
    24661 ctgctctatg cttctggtgg agcgagagta gatggccaac tcttggtaac tcgtctgcta
    24721 gaagccagtc atgtcaagct ggtcaaagaa aaagtgactc tgacaccgtt agcatcaggc
    24781 taccagattg gtgaagagga gtttgagcag gttattttgg cgacgggagc ttggttgggg
    24841 gacatgttag aacccttggg ttatgaagta gatgttcgtc ctcaaaaagg acaactacga
    24901 gattatcagc tggtccaaga tatggaagct taccctgttg tcatgccaga aggggagtgg
    24961 gatttgattc cttttgcagg tgggaaattg tccttaggcg ctacccacga aaatgacatg
    25021 ggatttgatt tgacggtaga tgaaaccttg ctccaacaaa tggaggaggc caccttgact
    25081 cactatctga ttttggctga agctacttca aaatctgagc gtgttggaat ccgtgcctac
    25141 accagtgatt tctctccttt ctttgggcag gtgcctgact taactggtgt ctatgcagcc
    25201 agtggattag gttcatcagg cctcacaact ggtcctatta ttggttacca tttagctcaa
    25261 ctgatccaag acaaggagtt gaccttggac cctgaaaact acccaattga aaactatgtc
    25321 aaacgagtaa aaagcgaata atactcaatg aaaatcaaag aacaaactag gtaactagcc
    25381 gcgggttact caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa
    25441 cactgttttg aggttgtaga tagaactgac gaagtcagta accataccca tggcaaggcg
    25501 acgttgacgt ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc
    25561 aggtagttta ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa
    25621 tctgagaatc gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt
    25681 attggaaccc acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat
    25741 aatcttgtca atagcaatcg taagagttta gaagttgttg aaagaattac aggagttgag
    25801 attcctttct atgaggcaga tattcgtgac acagctaccc tcagagatat tttcaagcag
    25861 gaagaaccga ctggtgtcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt
    25921 atccctcttg cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg
    25981 gaagaaaaca actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg
    26041 cacacagtgc ccatcttgga agatttccca ctttcagtga ccaacccata cggtcgtacc
    26101 aagctcatgc tagaggaaat tttgaccgat atttacaaag cagactcaga atggaatgtt
    26161 gtcttgcttc gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat
    26221 ccaaacggta ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta
    26281 gagcaagtgc aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgac
    26341 tatatccacg ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa
    26401 ggttcaggac taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt
    26461 atccaaaaca tggaaaaagc ggtgggacgt cctattcctt accgtatcgt agaacgtcgc
    26521 ccaggtgata tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg
    26581 gaagcagaac tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat
    26641 ccaaatggat ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga
    26701 ggaagtactt cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga
    26761 aatcgagtat gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc
    26821 ctatcgggag caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga
    26881 agcagccctt tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc
    26941 agacctccaa gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt
    27001 agacttggac tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag
    27061 tttctgtgct gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc
    27121 gggtgtccgt gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac
    27181 cgagtccaat cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt
    27241 ggactatcca aatgtcgaaa ggcaggctgg caagacaaat tggagtttta ggcaactctt
    27301 tttctactcc attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt
    27361 agctggtctc ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac
    27421 cctcattttg ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct
    27481 tggaggtatt caactcttga ccattgggat tctcggcaag tatatcagta agatttattt
    27541 agaaaccaaa aaaagaccgc tttatcttat caaagaaaaa agttatcata gatcatgaaa
    27601 aagtaggagt tatctagcgc agtcactttt ttgtaattat aattcttttg gtctggaact
    27661 tgagtgattt ttaaaaaaat tagggatttg acatgatata aatgaactat gtggaataaa
    27721 tttactgcaa agacgataac ttaataaata aaaaattcag gagggttatt ttatgctaag
    27781 taaagaggag tatattgaag aaatcgggct tatagagaaa caaaattatg tagaggttga
    27841 actgtatcct ttagttgctg atataattaa tccgacttta aaaaatagtt tatcaaaaag
    27901 atatgtcttc ggaagaagaa agagtaatat ggggcaaata tattatggtc taagtaattt
    27961 tcctgatata gttattttgg ataagaatta tcaaaataaa gccagaaaaa gtatagaaat
    28021 tgaagaatgg aagaaacttc gaggatgcgt ggaaattaag agtttaaagc atgatttaat
    28081 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    28141 gggacaactt attggagacc ttttatggta taaaaaagta atttatacaa atggaattga
    28201 atggagattt ctaagtttag atgacaagga agagatagat aatacaattg ttcaagtagt
    28261 taacaaaaga atagaaacag aagaagcggg aaattctttt gattggtgga agaatattaa
    28321 agatttatcg ttcaattata cggatatata tttatctaaa gattgtatac aagagtggga
    28381 tgaatttgta aagaaagtaa aggaaataga atggtaggag tctattctca ttgagaaatt
    28441 tagattataa gtcgcagtaa gatttattta gagactaaaa aaagaccact ttatcttatc
    28501 aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag actataattt
    28561 tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta ggcttcctgg
    28621 tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagatatc ctgactagga
    28681 gaaatttctt tttccagttg gtcagggtca tcgtaaaaac gcacgattcc attatcgtgg
    28741 taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg ttcaggtata
    28801 agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa aacaaggagt
    28861 aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa tcaagagcag
    28921 agcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt ttgacgatcc
    28981 tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc tatctatcat
    29041 cgggggggag taatcgcaca gcagccttaa aaggctttca tgattctgat gcaagtgtag
    29101 tacaaatctc atcttcaagc agttctcagc ctgagcagag ttcagagcca gaatctactt
    29161 ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc gcaggagaag
    29221 gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag gccttgaatc
    29281 ctgggcacat ggttacagga tcttggtttg ctaatccagg tgatgttata aaaataaaat
    29341 aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca gcggtaagag
    29401 tacggtcgca aagattattg ctaaggattt tggattcacc taccttgata caggagctat
    29461 gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag aagtcgaagc
    29521 ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa ctggagacca
    29581 gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg aagtgaccaa
    29641 tcatgtttct gctattgcag caattcctga agtgcgtgag aaactggttt ctctccaaca
    29701 agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa ctgttgtatt
    29761 gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag cagagcgtcg
    29821 ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa aaaaggaaat
    29881 tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac aagcagagga
    29941 tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa aaatcaaagc
    30001 agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg gtttttttct
    30061 aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa ttttgatttt
    30121 caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat tgtccaaaat
    30181 gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag tgtgctcatg
    30241 agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc gatgccaacg
    30301 gaaataaatt gactgatggt gatacagtaa ctctcatcaa ggacttgaaa gtaaaaggtg
    30361 cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta gaaggcgacc
    30421 acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca gagtttgtga
    30481 ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta tcttcttgtt
    30541 tctagcggct tttacgggag tttatcttga aattactaag catggtggtt ttgggatgct
    30601 tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt atcttctaaa
    30661 ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct taaaaggtgg
    30721 ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg cgcccattgc
    30781 gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca tctggttttt
    30841 agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc cagcagtgtg
    30901 gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg ttctaaaact
    30961 caatattcca aatgctaagg ataatccttt cccttacttc tttttgaatg tgaacaaggg
    31021 ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg tagcaggatt
    31081 tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt cgaaaatctc
    31141 ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgaaca acctgcggct
    31201 agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat tcattttcga
    31261 atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat ttgataacta
    31321 tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca atttttagaa
    31381 cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat ttcgagtgcc
    31441 ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga gctcttggtg
    31501 agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt agaaaaaata
    31561 tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag cggtacagct
    31621 cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt tggtttgggt
    31681 cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca aggaaaaagg
    31741 cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc tctcattacc
    31801 ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc ctatagtgct
    31861 ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc aaagaaagaa
    31921 gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg cttgattttt
    31981 accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac catccgtatt
    32041 ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt tgttcttagt
    32101 atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat ttctatcttt
    32161 aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat cgtgattgcc
    32221 ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt tgcctatagt
    32281 gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa actcctcaat
    32341 caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac cccatttgtt
    32401 ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat cttaggaggt
    32461 tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc ttaggattga
    32521 ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga ttgagtttgg
    32581 aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttt ctaatagagt
    32641 tattcatatc ttatttcaat ctactataga aagctagccg caggttgctc aaaatagtgt
    32701 tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcgaagag tatgagattt
    32761 ttatacccat acaatatttg ttttaggtcc ttgtttacag actaatttct tgataaaata
    32821 gaggttatga cgagatataa agcaactatt tcctatgatg gttatgcctt tgctggcttt
    32881 cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg aaaaaacctt gaccagatta
    32941 aataaagggc aaaccattac tgttcacggt gctggtagga cagatagtgg ggttcatgcc
    33001 ctgggacagg tcattcattt tgacctgcct tatcagatgg atgaggagaa actccgtttt
    33061 gccttggata cccagtctcc tgaagatatt gatgtgattt cgattgagct tgtggcagat
    33121 gattttcatt gccgttatgc caaacatagc aagacctatg agtttattgt ggatagagga
    33181 cgtcccaaaa atcctatgcg ccgtcactat gccacccact ttccctaccc actcgatgtg
    33241 gaacgaatgc agattgcaat caaaaagcta gagggaaccc atgattttac cggttttaca
    33301 gcctctggga ctagtgtaga ggataaggtt cgcaccatca cagaagctag tttaatagtc
    33361 gatgagacag gacaattttt gacctttacc ttttcaggaa atggtttctt gtataaacag
    33421 attcgcaata tggtggggac tcttctcaaa atcggtaaca accgcatgcc agtagagcag
    33481 attgatctca tcttggagaa gaaggacagg caacttgcag gtcccactgc agcaccaaat
    33541 ggtttgtatt taaaggagat tcgttatgaa gaataatcgt attttagcac tttctggaaa
    33601 tgatattttt agtggtggtg gactgtcagc tgatttggct acctatacct tgaacggctt
    33661 gcatgggttt gtagcagtga cttgtttgac agccttgaca gaaaaaggat ttgaagtctt
    33721 tccaactgat gataccattt ttcaacatga attagatagc ttgcgtgatg tggaatttgg
    33781 gggaattaag attggtcttc tccctactgt cagtgtggct gagaaggcct tggactttat
    33841 caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc ttggtctgca aggaaacgca
    33901 tgatgtagct gtcagtgagc tctgccaaga gttgattcgc tttttccctt atgtcagtgt
    33961 gattacgcct aatctcccag aagcagaatt attatccggt caggaaatta aaaccttgga
    34021 agacatgaaa actgcagcgc agaaattgca tgatttagga gctccagcag tcattatcaa
    34081 gggaggcaat cgtcttagtc aggacaaggc ggtggatgtc ttttatgatg gacagacctt
    34141 tactatccta gaaaatccag ttatccaagg ccaaaatgct ggtgcaggtt gtacctttgc
    34201 ctctagcatt gccagtcact tgattaaagg tgataaactt ttgccagcag tagaaagctc
    34261 taaggctttc gtttatcgtg ctattgcaca agcagatcag tatggagtaa gacaatatga
    34321 agcaaacaaa aacaactaaa atcgcccttg tatccctatt aaccgccctt tctgtggttc
    34381 taggttattt cttaaaaatc ccaacaccta caggaattct aactctttta gatgctggtg
    34441 tcttctttgc ggccttttac tttggtagtc gtgaaggagc ggtagtcgga ggactagcaa
    34501 gtttcttgat tgacctctta tcaggctacc ctcagtggat gttctttagc ttggtcaacc
    34561 atggcttgca gggatttttc gcaggattta aaggaaaaag tcagtggtta ggccttattt
    34621 tagcaattat tgccatggta ggaggctacg ccttgggttc tactttgatg aatggctggg
    34681 cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa tatggtaggg atgattgtag
    34741 gatttattct tagtcaaagt atcaagaaga ttaagtaata ctcttcgaaa atctcttcaa
    34801 accacgtcag cttccatctg caacctcaaa ccactgtttt gagcagcctg aggctagctt
    34861 tctagtttgc actttgattt tcattgagta taaagaggtt gagtaaaaag tatttcaaat
    34921 aagaaaaacg catagtatca ggtgttgaat gaactgcccc ccaaaagtta gacagaaaaa
    34981 atctaacttt tggggtgttt tattatgaaa ctaacttatg atgataaagt tcagatctat
    35041 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaacaat
    35101 tctaatctta ggtatatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
    35161 ggaaaaaatc gttactattc tcctgattta aaacaagaaa tgattaataa agtcttacat
    35221 gaaggctgga ctaaagatag agt
//
LOCUS       DAVKUR010000018        34397 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKUR010000018 DAVKUR010000000
VERSION     DAVKUR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.018"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            554..1006
                     /locus_tag="VW749_000978"
     CDS             554..1006
                     /locus_tag="VW749_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0175026.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1025..2362
                     /locus_tag="VW749_000979"
     CDS             1025..2362
                     /locus_tag="VW749_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0175027.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2441..3325
                     /locus_tag="VW749_000980"
     CDS             2441..3325
                     /locus_tag="VW749_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0175028.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3325..4158
                     /locus_tag="VW749_000981"
     CDS             3325..4158
                     /locus_tag="VW749_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0175029.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4176..6269
                     /gene="nanB"
                     /locus_tag="VW749_000982"
     CDS             4176..6269
                     /gene="nanB"
                     /locus_tag="VW749_000982"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0175030.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6281..7384
                     /locus_tag="VW749_000983"
     CDS             6281..7384
                     /locus_tag="VW749_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0175031.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7557..8255
                     /locus_tag="VW749_000984"
     CDS             7557..8255
                     /locus_tag="VW749_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0175032.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8274..9791
                     /locus_tag="VW749_000985"
     CDS             8274..9791
                     /locus_tag="VW749_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0175033.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9916..11244
                     /locus_tag="VW749_000986"
     CDS             9916..11244
                     /locus_tag="VW749_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0175034.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11496..12362
                     /locus_tag="VW749_000987"
     CDS             11496..12362
                     /locus_tag="VW749_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0175035.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12378..13217
                     /locus_tag="VW749_000988"
     CDS             12378..13217
                     /locus_tag="VW749_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0175036.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13489..13941
                     /locus_tag="VW749_000989"
     CDS             13489..13941
                     /locus_tag="VW749_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0175037.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14074..14382
                     /locus_tag="VW749_000990"
     CDS             14074..14382
                     /locus_tag="VW749_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175038.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14392..14691
                     /locus_tag="VW749_000991"
     CDS             14392..14691
                     /locus_tag="VW749_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175039.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            14673..15317
                     /locus_tag="VW749_000992"
     CDS             14673..15317
                     /locus_tag="VW749_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0175040.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15486..16403
                     /locus_tag="VW749_000993"
     CDS             15486..16403
                     /locus_tag="VW749_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0175041.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16421..17305
                     /locus_tag="VW749_000994"
     CDS             16421..17305
                     /locus_tag="VW749_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0175042.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17321..18172)
                     /locus_tag="VW749_000995"
     CDS             complement(17321..18172)
                     /locus_tag="VW749_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0175043.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18372..20429
                     /gene="pbp2b"
                     /locus_tag="VW749_000996"
     CDS             18372..20429
                     /gene="pbp2b"
                     /locus_tag="VW749_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0175044.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20440..21036
                     /gene="recR"
                     /locus_tag="VW749_000997"
     CDS             20440..21036
                     /gene="recR"
                     /locus_tag="VW749_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0175045.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21212..22255
                     /locus_tag="VW749_000998"
     CDS             21212..22255
                     /locus_tag="VW749_000998"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0175046.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22339..23712
                     /locus_tag="VW749_000999"
     CDS             22339..23712
                     /locus_tag="VW749_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0175047.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            23699..24310
                     /locus_tag="VW749_001000"
     CDS             23699..24310
                     /locus_tag="VW749_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0175048.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24401..25105
                     /locus_tag="VW749_001001"
     CDS             24401..25105
                     /locus_tag="VW749_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0175049.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25324..26697
                     /gene="ftsA"
                     /locus_tag="VW749_001002"
     CDS             25324..26697
                     /gene="ftsA"
                     /locus_tag="VW749_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0175050.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26714..27973
                     /gene="ftsZ"
                     /locus_tag="VW749_001003"
     CDS             26714..27973
                     /gene="ftsZ"
                     /locus_tag="VW749_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0175051.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27978..28649
                     /locus_tag="VW749_001004"
     CDS             27978..28649
                     /locus_tag="VW749_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0175052.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28659..29198
                     /locus_tag="VW749_001005"
     CDS             28659..29198
                     /locus_tag="VW749_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0175053.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29198..29461
                     /locus_tag="VW749_001006"
     CDS             29198..29461
                     /locus_tag="VW749_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0175054.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29458..30243
                     /locus_tag="VW749_001007"
     CDS             29458..30243
                     /locus_tag="VW749_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0175055.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30252..31040
                     /gene="divIVA"
                     /locus_tag="VW749_001008"
     CDS             30252..31040
                     /gene="divIVA"
                     /locus_tag="VW749_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0175056.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31388..34180
                     /locus_tag="VW749_001009"
     CDS             31388..34180
                     /locus_tag="VW749_001009"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0175057.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEYVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPTQDAVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10580 a         6055 c         7483 g        10279 t
ORIGIN      
        1 actaatttag agaatgaaat atagagtatt tctctcttaa aagtttttgg tgaaacgaga
       61 tgtagaaagg agatttagcc aaagagtcta ttagtgctag aataatagat tagaattatt
      121 ttagaaaaac gaagtgagca gcttataaat tcaagtcccc aaatagattc atactagtat
      181 cttttgcaaa aaataaaggg cgacttcctt catgaatatc aatttcatct ataaggaagg
      241 tagctaattg aactaactta tttattctgt ttgtcgctag aaaaatcaga cctccttgtg
      301 aagattgagg agatactgaa tgaaaatcaa agaagaaact agcaagctag tagcagattg
      361 cccaaaacac cgctttgagg ttgtagataa gactgacgta tataatccaa ggtgaagcga
      421 ctgtggtttg aagagatttt caaagagtat aggctagaga gtagtgtttt tatgtccttc
      481 tagtagaaaa tgctagacag aagaatgggg aacttggata ggaaaaatag attgagaaag
      541 gaggttagaa gagatgatta ttacaaaaat tagccgttta ggaacttatg tgggagtaaa
      601 tccacatttt gcaacattaa tagatttttt agaaaaaaca ggactagaaa atttaacaga
      661 aggttcgatt gctatcgatg gtaatcgatt gtttgggaat tgctttactt atctagcaga
      721 tggtcaagca ggggctttct ttgaaacaca ccaaaaatat ttggatattc atttagtttt
      781 ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat gtaagcgtta cccaagaata
      841 tgatgaagag aaagatattg aattatacac agggaaagtg gaacagttgg ttcatttgag
      901 agctggtgaa tgcctcatca cttttccaga agatttacat caacccaagg ttcgtataaa
      961 tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt tcttaatgta gaaagagaag
     1021 aacgatgaaa aaaatgagaa agtttttatg tctagctgga attgcgctag cggctgttgc
     1081 cttggtagct tgttcaggaa aaaaagaagc tacaactagt actgaaccac caacagaatt
     1141 atctggtgag attacaatgt ggcactcctt tactcaagga ccccgtttag aaagtattca
     1201 aaaatcagca gatgctttca tgcaaaagca tccaaaaacg aaaatcaaga ttgaaacatt
     1261 ttcttggaat gacttctata ctaaatggac tacaggttta gcaaatggaa atgtgccaga
     1321 tatcagtaca gctcttccta accaagtaat ggaaatggtc aactcagatg ctttggttcc
     1381 gctaaatgat tctatcaagc gtattggaca agataaattt aacgaaactg ccttaaatga
     1441 agcaaaaatc ggagatgatt actactctgt tcctctttat tcacatgcac aagtcatgtg
     1501 ggttagaaca gatttgttaa aagaacataa tattgaggtt cctaaaactt gggatcaact
     1561 ctatgaagct tctaaaaaat tgaaagaagc tggagtttat ggcttgtctg ttccgtttgg
     1621 aacaaatgac ttaatggcaa cacgtttctt gaacttctac gtacgtagtg gtggaggaag
     1681 cctcttaaca aaagatctta aagcagactt gacaagccaa cttgctcaag atggtattaa
     1741 atactgggtt aaattgtata aagaaatctc acctcaagat tctttgaact ttaatgtcct
     1801 tcaacaagct accttgttct atcaaggaaa aacagcattt gactttaact ctggcttcca
     1861 tatcggagga attaatgcca acagtcctca attgattgat tcgattgatg cttatcctat
     1921 tccaaaaatc aaagagtctg ataaagacca aggaattgaa acctcaaaca ttccaatggt
     1981 tgtttggaaa aattcaaaac atccagaagt tgctaaagca ttcttagaag cactttataa
     2041 tgaagaagac tacgttaaat tccttgattc aactccagta ggtatgttgc caactattaa
     2101 ggggattagc gattctgcag cctataaaga aaatgaaact cgtaagaaat ttaaacatgc
     2161 tgaagaagta attactgaag ctgttaaaaa aggtactgct attggttatg aaaatggacc
     2221 aagtgtacaa gctggtatgt taactaacca acacattatt gaacaaatgt tccaagatat
     2281 cattacaaat ggaacagatc ctatgaaagc agcaaaagaa gcagaaaaac aattaaacga
     2341 tttatttgag gctgttcagt agatgtaaaa gactagaaaa taggtgggct agtgagctga
     2401 aaagctctag cccaatcttg taaaagaagg gagaaggaga atggttaaag aacgtaattt
     2461 aactcgctgg atatttgttt tgccagctat gattatcgta ggattactct ttgtttatcc
     2521 gtttttctcg agtatttttt atagctttac caataagcat ttgattatgc ctaattataa
     2581 atttgttggt ttggctaact ataaagctgt gctgtcagat cccaacttct ttaatgcgtt
     2641 ctttaattca attaagtgga ccgttttctc attagttggt caagttttag tagggtttgt
     2701 attggcttta gctcttcaca gagtacgcca cttcaagaaa ttatatagga ccttattgat
     2761 tgttccttgg gcatttccta ccatcgttat tgccttctct tggcagtgga ttctaaacgg
     2821 ggtttatggc tacttaccta atctaatcgt aaaattaggt ttaatggaac atacacctgc
     2881 atttttgaca gatagtacat gggcattcct atgtttggtg tttatcaaca tttggtttgg
     2941 agcaccaatg attatggtta atgtgctttc agctttgcaa acagtaccag aagaacaatt
     3001 tgaggctgct aagatagatg gtgcttcaag ttggcaggtg ttcaagttta tcgtctttcc
     3061 acatattaaa gtggttgtag gacttctagt tgttttgaga actgtatgga tctttaataa
     3121 ctttgacatt atctacctca ttactggtgg tggaccagcc aatgctacaa cgacacttcc
     3181 aatttttgct tacaacctgg gttggggaac taaattgttg ggtcgtgctt cagcagttac
     3241 agtattgctc tttatcttct tggtggcgat ttgctttatc tactttgcta tcatcagtaa
     3301 gtgggaaaag gagggtagaa aataatgaag aagaaatcca gtatttattt agatattctc
     3361 tcacatgtac ttttagttgg tgcgaccatc gttgcaattt tcccattggt atggattatc
     3421 atatcttctg tcaaagggaa aggggaatta actcagtatc caacacgatt ttggcctgaa
     3481 cagtttacat tagattattt cactcatgtt atcaacgatt tgcacttcat tgataacatt
     3541 cgaaacagtt taatcattgc cttggctaca accctcattg cgattattat ttctgctatg
     3601 gcagcctatg gtattgttcg attctttcct aaattgggag caatcatgtc gagactactc
     3661 gtcattacct acattttccc accaattttg ttagcaattc cctattcaat tgccattgct
     3721 aaagttgggt taacaaatag tttatttggc ttgatgatgg tttatctatc ttttagtgtt
     3781 ccatatgcag tttggctctt agttggattt ttccaaacag ttccaattgg aattgaagaa
     3841 gcggctagaa ttgatggtgc aaataaattt gttacgtttt ataaggttgt gctaccgatt
     3901 gtagcaccag gtattgtagc aacagctatt tatacattta tcaatgcttg gaatgaattc
     3961 ctgtatgcct tgattttaat taacaataca ggaaagatga cagtagcagt agcccttcgt
     4021 tcacttaatg gttcagaaat actagactgg ggagatatga tggcagcgtc tgttattgta
     4081 gttcttccat caattatttt cttctctatc atccaaaata agattgcaag tggattatca
     4141 gaaggatctg tgaagtagac gaaagaagga aaaaaatgaa taaaagaggt ctttattcaa
     4201 aactaggaat ttctgttgta ggcattagtc ttttaatggg agtccccact ttgattcatg
     4261 cgaatgaatt aaactatggt caactgtcca tatctcctat ttttcaagga ggttcatatc
     4321 aactgaacaa taagagtata gatatcagct ctttgttatt agataaattg tctggagaga
     4381 gtcagacagt agtaatgaaa tttaaagcag ataaaccaaa ctctcttcaa gctttgtttg
     4441 gcctatctaa tagtaaagca ggctttaaaa ataattactt ttcaattttc atgagagatt
     4501 ctggtgagat aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcta
     4561 gaccagcttc attatgggga aagcataaag gacaggcagt tgaaaataca ctagtatttg
     4621 tatctgattc taaagataaa acatacacaa tgtatgttaa tggaatagaa gtgttctctg
     4681 aaacagttga tacatttttg ccaatttcaa atataaatgg tatagataag gcaacactag
     4741 gagctgttaa tcgtgaaggt aaggaacatt acctcgcaaa aggaagtatt ggtgaaatca
     4801 gtctatttaa caaagcaatt agtgatcagg aagtttcaaa tattcccttg tcaaatccat
     4861 ttcagttaat tttccaatca ggagattcta ctcaagctaa ctattttaga ataccgacac
     4921 tatatacatt aagtagtgga agagttctat caagtattga tgcacgttat ggtgggactc
     4981 atgattctaa aagtaagatt aatattgcca cttcttatag tgatgataat gggaaaacgt
     5041 ggagtgagcc aatttttgct atgaagttta atgactatga ggagcagtta gtttactggc
     5101 cacgagataa taaattaaag aatagtcaaa ttagtggaag tgcttcattc atagattcat
     5161 ccattgttga agataaaaaa tctgggaaaa cgatattact agctgatgtt atgcctgcgg
     5221 gtattggaaa taataatgca aataaagccg actcaggttt taaagaaata aatggtcatt
     5281 attatttaaa actaaagaag aatggagata acgatttccg ttatacagtt agagaaaatg
     5341 gtgtcgttta tgatgaaaca actaataaac ctacaaatta tactataaat gataagtatg
     5401 aagttttgga gggaggaaag tctttaacag tcgaacaata ttcggttgat tttgatagtg
     5461 gctctttaag agaaaggcat aatggaaaac aggttcctat gaatgttttc tacaaagatt
     5521 cgttatttaa agtgactcct actaattata tagcaatgac aactagtcag aatagaggag
     5581 agagttggga acaatttaag ttgttgcctc cgttcttagg agaaaaacat aatggaactt
     5641 acttgtgtcc tggacaaggt ttagcattaa aatcaagtaa cagattgatt tttgcaacat
     5701 atactagtgg agaactaacc tatctcattt cggatgatag tggtcaaaca tggaagaaat
     5761 cctcagcttc aattccgttt aaaaatgcaa cagcagaagc acaaatggtt gaactgagag
     5821 atggtgtgat tagaacattc tttagaacca ctacaggtaa gatagcttat atgactagta
     5881 gagattctgg agaaacatgg tcgaaagttt cgtatattga tggaattcaa caaacttcat
     5941 atggcacaca agtatctgca attaaatact ctcaattaat tgatggaaaa gaagcagtca
     6001 ttttgagtac accaaattct agaagtggcc gtaagggagg ccaattagtt gtcggtttgg
     6061 tcaataaaga agatgatagt attgattgga gataccacta tgatattgat ttgccttcgt
     6121 atggttatgc ctattctgcg attacagaat tgccaaatca tcacataggt gtactgtttg
     6181 aaaaatatga ttcgtggtcg agaaatgaat tgcatttaag caatgtagtt cagtatatag
     6241 atttggaaat taatgattta acaaaataaa ggagaaaaac atggttaaat acggtgttgt
     6301 tggagcaggg tattttggag ctgaattggc tcgctacatg caaaagaatg atggagcaga
     6361 gattactctt ctctatgatc cagataatgc agaggcgatt gcagaagaat tgggagcaaa
     6421 agtagcaagt tccttagatg agttggtttc tagcgatgaa gtagattgtg ttatcgtcgc
     6481 aactccaaat aatcttcata aggaaccggt tattaaggct gcacagcatg gtaaaaatgt
     6541 tttctgtgaa aaaccaattg cgctttctta tcaagattgt cgcgagatgg tagatgcgtg
     6601 taaagaaaac aatgtaacct ttatggcagg acatattatg aatttcttta atggtgttca
     6661 tcatgcaaaa gaactcatta atcaaggagt tatcggagac gttctatatt gtcatacagc
     6721 tcgtaatggt tgggaagaac aacaactgtc agtatcatgg aaaaaaattc gtgaaaaatc
     6781 aggtggtcac ttgtatcacc acatccatga attggattgc gttcaattcc ttatgggggg
     6841 catgcctgaa actgtaacca tgacaggtgg aaatgtggcc catgaaggtg aacatttcgg
     6901 tgatgaagat gatatgattt ttgtcaatat ggaattttct aataagcgtt ttgccttgtt
     6961 agaatggggt tcagcttatc gttggggtga acattatgtc ttaatccaag gaagcaaagg
     7021 tgccatccgc ttagacttat tcaactgtaa aggaactctt aagctagatg ggcaagaaag
     7081 ctatttcttg attcacgaat cgcaagaaga agatgatgat cggactcgta tctatcatag
     7141 tacagagatg gatggagcaa ttgcttatgg taaaccaggt aaacgtactc cattatggct
     7201 atcatctgtc attgataaag aaatgcgcta tctgcatgag attatggaag gagctccagt
     7261 atcagaagaa tttgcaaaac ttttgacagg tgaagctgcc ctagaagcaa ttgctactgc
     7321 agatgcttgt acccagtcta tgtttgaaga tcgcaaagta aaattgtcag aaattgtaaa
     7381 ataaattttg gtattctcct attataggtc gacttgctcc tctgaaagta cttttagagg
     7441 agctgtttga cttggctagt ttttgaaact gaaatctatt atactacaaa ctattgaaag
     7501 cgttttaatt ttaaggtata ataatctcat agaaataaag aaaaggagga aagaggatgc
     7561 cacagattag caaagaagcc ttgattgagc aaatcaaaga tggaatcatc gtttcttgtc
     7621 aggctcttcc tcatgaaccg ctttatacag aagcgggagg ggtgattccc ttgctggtca
     7681 aagcggctga gcaaggtgga gcagtcggta tccgagcaaa cagtgttcgc gatatcaagg
     7741 aaattaagga agtcactaaa cttccaatca ttgggattat caaacgtgat tatccacctc
     7801 aggaaccctt catcacggct actatgaaag aagttgatga attggcagaa ctggacatcg
     7861 aggtgattgc tctggattgt accaagcgtg aacgctacga tggtttggaa attcaagagt
     7921 tcattcgtca ggttaaggag aaatatccta atcagctttt gatggctgat actagtatct
     7981 tcgaagaagg gctagcagct gtagaagcag gaattgactt tgtcggaaca accttatcag
     8041 gctacacatc ctacagtcca aaagtagacg gtccagattt tgaattgatt aagaaactct
     8101 gtgatgccgg tgtagatgtc attgcagaag gaaaaattca tacaccagaa caagccaaac
     8161 aaatccttga atatggagtg cgaggcatcg ttgttggtgg cgccattact agaccaaaag
     8221 agattacaga acgcttcgtt gctagtctta aataagatgt gagggggagt tttatgttta
     8281 aagttttaca aaaagttgga aaagctttta tgttacctat agctatactt cctgcagcag
     8341 gtctactttt ggggattggt ggtgcacttt caaacccaac cacgatagca acttatccaa
     8401 tactagacaa tagtattttt caatcaatat tccaagtaat gagctctgca ggagaggttg
     8461 tattcagtaa tttgtcacta cttctctgtg tgggattatg tattggctta gcgaaacgag
     8521 ataaaggaac cgctgcgtta gcaggagtaa ctggttactt agttatgact gcaacgatca
     8581 aagctttggt aaaacttttt atggcagaag gatctgcaat tgatactgga gttattggag
     8641 cattagttgt cggaatagtt gccgtatatt tgcacaaccg atataacaat attcaattac
     8701 cttccgcttt aggattcttt ggaggttcac gcttcgttcc tattgttaca tcgttctctt
     8761 ctatcttgat tggctttgtc ttctttgtta tttggccacc tttccaacaa cttcttgttt
     8821 ctacaggtgg atatatttct caggcgggtc caattggaac ttttctatat ggatttttaa
     8881 tgagactttc tggagcagta ggcttacatc atataattta ccctatgttt tggtatactg
     8941 aacttggtgg tgttgaaact gttgcaggac aaacagtggt tggagctcaa aaaatatttt
     9001 ttgctcaatt agccgatccg gcccattctg gattatttac agaaggaaca aggttttttg
     9061 caggtcgttt ctcaacaatg atgttcggtt taccggctgc ctgtttagcg atgtaccata
     9121 gtgttcctaa aaatcgtcgt aaaaaatacg cgggtttgtt ttttggagtt gctttaacat
     9181 cttttattac cggtattaca gaaccaattg aatttatgtt tctattcgtc agtccggttc
     9241 tatatgttgt tcacgcattc cttgatggtg ttagcttctt tattgcagac gtcttaaata
     9301 tttcaatagg aaacacattt tcaggaggtg taatcgattt cactttattt ggaattttgc
     9361 aggggaacgc taagacgaat tgggttcttc agattccaat tggacttatt tggagtgttt
     9421 tgtattatat tatttttaga tggttcatta ctcaattcaa cgttctaacg ccaggacgag
     9481 gagaagaagt agattctaaa gaaatttctg aatccgcaga ttcaacttca aatactgcag
     9541 attatttaaa acaggatagc ctacaaatta tcagagcctt gggtggatca aataatatag
     9601 aagatgtaga tgcttgtgtg acacgtttac gtgtagctgt aaaagaagtt aatcaagttg
     9661 ataaagcact tttaaaacaa attggtgcag ttgatgtctt agaagtgaag ggtggcattc
     9721 aagcaatcta tggagcaaaa gcaatcttat ataaaaatag tattaatgaa attttaggtg
     9781 tagatgatta agtacttact gacttaataa aaaacagagg agagtgatgg atgagtagga
     9841 tgaaatgaaa tcgcatacaa gaaataaaga actcattatc caagttggat acgcttatta
     9901 cataggagaa tacaaatgaa atttagaaaa ttagcttgta cagtacttgc gggtgctgcg
     9961 gttcttggtc ttgctgcttg tggcaattct ggcggaagta aagatgctgc caaatcaggt
    10021 ggtgacggtg ccaaaacaga aatcacttgg tgggcattcc cagtatttac ccaagaaaaa
    10081 actggtgacg gtgttggaac ttatgaaaaa tcaatcatcg aagcgtttga aaaagcaaac
    10141 ccagatataa aagtgaaatt ggaaaccatc gacttcaagt caggtcctga aaaaatcaca
    10201 acagccatcg aagcaggaac agctccagac gtactctttg atgcaccagg acgtatcatc
    10261 caatacggta aaaacggtaa attggctgag ttgaatgacc tcttcacaga tgaatttgtt
    10321 aaagatgtca acaatgaaaa catcgtacaa gcaagtaaag ctggagacaa ggcttatatg
    10381 tatccgatta gttctgcccc attctacatg gcaatgaaca agaaaatgtt agaagatgct
    10441 ggagtagcaa accttgtaaa agaaggttgg acaactgatg attttgaaaa agtattgaaa
    10501 gcacttaaag acaagggtta cacaccaggt tcattgttca gttctggtca agggggagac
    10561 caaggaacac gtgcctttat ctctaacctt tatagcggtt ctgtaacaga tgaaaaagtt
    10621 agcaaatata caactgatga tcctaaattc gtcaaaggtc ttgaaaaagc aactagctgg
    10681 attaaagaca atttgatcaa taatggttca caatttgacg gtggggcaga tatccaaaac
    10741 tttgccaatg gtcaaacatc ttacacaatc ctttgggcac cagctcaaaa tggtatccaa
    10801 gctaaacttt tagaagcaag taaggtagaa gtggtagaag taccattccc atcagacgaa
    10861 ggtaagccag ctcttgaata ccttgtaaac gggtttgcag tattcaacaa taaagacgac
    10921 aagaaagtcg ctgcatctaa gaaattcatc cagtttatcg cagatgacaa ggagtgggga
    10981 cctaaagacg tagttcgtac aggtgctttc ccagtccgta cttcatttgg aaaactttat
    11041 gaagacaaac gcatggaaac aatcagcggc tggactcaat actactcacc atactacaac
    11101 actattgatg gatttgctga aatgagaaca ctttggttcc caatgttgca atctgtatca
    11161 aatggtgacg aaaaaccagc agatgctttg aaagccttca ctgaaaaagc gaacgaaaca
    11221 atcaaaaaag ctatgaaaca atagtcctta gttattctat aaaaagtagt tttttaaaga
    11281 acctaagagt gtataccccc ttttccctct acacagatag tgtaagaaaa gggggctttt
    11341 gtttaaaatg taagaaactg tcacgaaatt aaaatgaagt tcttacataa gcgaatcata
    11401 aaaaatttca ttttgatttt aaaacagttc aagaaagtca aaaaattatt ctatttgaaa
    11461 gagaggtgcc gactgtgaaa gtcaataaaa tccgtatgcg ggaaacagtg atttcctacg
    11521 ctttcctagc accagtatta ttcttctttg tcatctttgt gttggctccg atggtgatgg
    11581 gcttcattac aagtttcttt aactactcaa tgactaaatt tgagtttgta ggcttggata
    11641 actatatccg tatgtttaaa gatcctgtct ttacaaaatc tctgattaac acagttattt
    11701 tggttattgg atctgtacca gttgttgttc tattctcact ctttgtagca tctcagacct
    11761 atcatcaaaa tgtcattgcc agatccttct accgtttcgt cttcttcctt cctgttgtaa
    11821 cgggtagtgt tgccgtgaca gttgtttgga aatggattta tgacccacta tcagggattc
    11881 taaactttgt ccttaagtcc agccacatca tcagccaaaa catttcttgg ttgggagata
    11941 aaaactgggc attgatggcg attatgatta ttctcttgac cacttcagtt ggtcagccca
    12001 tcatccttta tatcgctgcc atggggaata ttgacaattc actggttgaa gcggcgcgtg
    12061 ttgatggtgc aactgagttt caagtttttt ggaagattaa atggccaagc cttcttccaa
    12121 caactcttta tattgcaatc atcacaacaa ttaactcatt ccagtgtttt gccttgattc
    12181 agcttttgac atctggtggt ccaaactact caacaagtac cttgatgtac tacctttacg
    12241 aaaaagcctt ccaattgaca gaatacggct atgccaacac aattggtgtc ttcttggcag
    12301 tcatgattgc tatcgtaagc tttgttcaat ttaaagtact tggaaacgac gtagaatact
    12361 aaagaaagga gacagctatg caatctacag aaaaaaaacc attaacagcc tttactgtta
    12421 tttcaacaat cattttgctc ttgttgactg tgctgttcat ctttccattc tactggattt
    12481 tgacaggggc attcaaatca caacctgata caattgttat tcctcctcag tggttcccta
    12541 aaatgccaac catggaaaac ttccaacaac tcatggtgca gaaccctgcc ttgcaatgga
    12601 tgtggaactc agtatttatc tcattggtaa ccatgttctt agtttgtgca acctcatctc
    12661 tagcaggtta tgtattggct aaaaaacgtt tctatggtca acgcattcta tttgctatct
    12721 ttatcgctgc tatggcgctt ccaaaacaag ttgtccttgt accattggta cgtatcgtca
    12781 acttcatggg aatccacgat actctctggg cagttatctt gcctttgatt ggatggccat
    12841 tcggtgtctt cctcatgaaa caatttagtg aaaatattcc tacagagttg cttgaatcag
    12901 ctaaaatcga cggttgtggt gagattcgta ccttctggag tgtagccttc ccgattgtga
    12961 aaccagggtt tgcagccctt gcaatcttta ccttcatcaa tacttggaat gactacttca
    13021 tgcaattggt aatgttgact tcacgtaaca atttgaccat ctcacttggg gttgcgacca
    13081 tgcaggctga aatggcaacc aactatggtt tgattatggc aggagctgcc cttgctgctg
    13141 ttccaatcgt cacagtcttc ctagtcttcc aaaaatcctt cacacagggt attactatgg
    13201 gagcggtcaa aggataatac tctgagaaaa tctcttcaaa ctacgtcagc gtcaccttgc
    13261 catacttaag tattgcctgc ggttagcttc ctagtttgtt cttcaatttt cattgagtat
    13321 aggaaaatca atctatcaag atacagaagt atattttata gatttagaga atatagaggt
    13381 tataagtgtc tacaaaatgg agggtatgca gttactttat gaagttttgt cagacactta
    13441 taaacttaag aatggtttta gttaactatc agaaacgaag gaaagagtat gatttttgac
    13501 gatttgaaaa acatcacctt ttacaaaggg attcatccta atttagacaa ggctatcgac
    13561 tatctctacc aacatcgtaa ggattctttc gaattaggaa agtatgatat tgatggagat
    13621 aaagtctttc tagttgttca ggaaaatgtc ctcaatcaag ctgaaaatga tcaatttgag
    13681 tatcataaga actatgcaga tttgcatttg ctggtagaag gacatgaata ttcgagctac
    13741 ggttcacgta tcaaagacga ggcagtagca ttcgacgaag cgagtgacat tggctttgtt
    13801 cattgtcatg aacactaccc actcttgttg ggttatcaca attttgcgat tttcttccca
    13861 ggtgagccac atcagccaaa tggttatgca ggcatggaag aaaaggttcg gaaatatctc
    13921 tttaaaattt tgattgatta aaaataggat gaattgtttt tttgtaaagc tttgacaata
    13981 ctctaccatg aaattgatct ttgtgaggta gggaaatgag aataaaatat ttaaaaattg
    14041 gtatcttcta agtatgctgc aagagctagt ttcttggatg gacagggaat tacagttgat
    14101 gagatggctt ggataattag gggcattgtg aatggattga ttggtagata cataaaatta
    14161 ggtacttatg cagccaagta tggtattagt atggcgcgtt cgatcttaag tagggcagct
    14221 gcaactgcag cagcaagagt aggattatcg accaagattt ctggatggat tttacgagta
    14281 gctgtgaatg tagctgatgt atatggtaat tttgccaaca atattgctgc agcttgggat
    14341 gcacatgata aaattcctaa caatggtcgt ataaactttt aaaatgcgag aatgaaagca
    14401 ctttgtattt ttttattgaa tatgttagct tggacagtgc ttgcaatgat aattcgtgga
    14461 gggctagatg gatttgatga gcatacttgg agtactattt taattgcttc gctgttcggg
    14521 gtatatgatt ataagcccat agataaaaat agaaaaaagt ccaaaagaaa aaagaaaaaa
    14581 gaaaaaatag atttgttcat ggtagggact tatgaaagct ttactgacaa aaaagaaaac
    14641 agtttacaaa gaaaaatgat ggaggagcaa acatggcaca aaaaggagta agccttatca
    14701 aggcagcatt tgatacagac aactttctca tgcgttttag tgagaaagtc ttggacatcg
    14761 tgacagccaa tcttcttttt gtcgtctctt gtttgcccat cgtgacgatt ggagtggcta
    14821 aaatcagcct ctacgagacc atgttcgaag ttaagaagag cagacgggtg cctgttttta
    14881 aaatctatct aagatctttc aagcaaaatc tgaaactagg tcttcagctg ggtttaatgg
    14941 agttaggaat tgtgtttctt accctttcag atctctatct tttctggggt caaacagctc
    15001 tgcccttcca attgctgaaa gccatttgtt taggtattct gatttttctt actatcgtga
    15061 tgctggctag ttaccctatc gcggcacgtt atgacctatc ttggaaagaa attcttcaaa
    15121 aaggattgat gttggctagt tttaactttc cttggttctt cctcatgtta gccattcttg
    15181 tcctcattgt gatggttctt tatctgtccg ccttcagtct actcttaggt ggctcagtct
    15241 tcttactttt tgggtttgga ctattggtct ttatccagac tggattgatg gagaaaattt
    15301 tcgcaaaata ccaataggag ccttatttct gaaactactt tcaaacgctc caaacgctat
    15361 tctataagcg agaaactaaa atctaagtgt ctataagata ttgaaagcct tttcggtaaa
    15421 gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat aataggagaa
    15481 aatctatgtc agatttgaaa aaatacgaag gtgtcattcc agccttctac gcatgttatg
    15541 atgaacaagg agaagtaagc ccagaacgta cgcgtgcctt ggttcaatac ttcattgata
    15601 aaggtgttca aggtctttat gtcaatggtt cttctggtga atgtatctac caaagtgttg
    15661 aagaccgcaa gttaatcttg gaagaagtca tggcggtagc caaaggtaaa ttgaccatca
    15721 ttgctcatgt tgcctgcaac aatactaaag atagtatgga acttgctcgc catgctgaaa
    15781 gcttgggagt agatgctatt gcaacgattc caccaattta tttccgcttg ccagaatact
    15841 cagttgccaa atactggaac gatatcagtt ctgcagctcc aaacacagac tacgtgattt
    15901 acaacattcc tcaattggca ggggttgctt tgactccaag cctttacaca gaaatgttga
    15961 aaaatcctcg tgttatcggt gttaagaact cttctatgcc agttcaagat atccaaacct
    16021 ttgtcagcct tggtggggaa gaccatatcg tctttaatgg tcctgatgag cagttcctag
    16081 gaggacgcct catgggtgct agggctggta tcggtggtac ttatggtgct atgccagaac
    16141 tcttcttgaa actcaatcag ttgattgcgg ataaggacct agaaacagcg cgtgaattgc
    16201 agtatgctat caacgcaatc attggtaaac tcacttctgc tcatggaaat atgtacggtg
    16261 tcattaaaga agtcttgaaa atcaatgaag gcttgaatat tggatctgtt cgttcaccat
    16321 tgacaccagt gactgaagaa gatcgtccag ttgtagaagc ggctgctgcc ttgattcgtg
    16381 aaaccaagga gcgcttcctc taatctaaaa ggaggtattt atgacatact acgttgcaat
    16441 tgatatcggt ggaaccaaca tcaagtatgg tttggttgat caagaggggc aacttcttga
    16501 atcgcatgaa atgccaactg aggcgcataa gggtggacct catatcttac aaaagaccaa
    16561 agatatcgta gctagttatt tagaaaaagg cccagtagca ggtgttgcca tatcttctgc
    16621 tgggatggtg gatccggata agggtgagat tttctatgct gggcctcaaa tccctaacta
    16681 cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt actattcctt gtgagattga
    16741 aaatgatgtc aactgtgcag gtcttgctga ggcagtatct ggttcaggca agggagcaag
    16801 tgtgacactt tgcttgacca ttggaaccgg tatcggtggt tgcttgatta tggataggaa
    16861 agtcttccat ggttttagca attcagcctg tgaagtcggg tatatgcata tgcaggatgg
    16921 agcttttcag gatctcgctt ctacaacagc tttagtgaaa tatgtagctg aagcccatgg
    16981 agaagatgtt gatcagtgga atggccgacg tatctttaag gaagctactg aaggaaacaa
    17041 aatctgcatg gaaggtattg accgtatggt tgactatcta ggaaaaggtc tggcaaatat
    17101 ttgttatgtg gccaatccag aagtggttat tcttggtggt ggtatcatgg ggcaagaggc
    17161 tatcctcaaa cctaagatcc gcacagcctt gaaagaggca ttggtaccaa gtttagcaga
    17221 aaaaacacga ttagaatttg cccatcacca aaatacagca gggatgttgg gtgcatatta
    17281 tcattttaag acaaaacaat cctagtttgg ctcagccaaa ctaggatttt cttacacgtt
    17341 tttgtctacg atagccgttg agttttttat tttcccagta gctattaaag attttttcct
    17401 tgctttcgcg attgatttcc aaaaagtagg cataaatcaa atcgataaag aagagcatag
    17461 gaagttgagc ggatattcgt tggatgtagg agggttggct gtgggtggct acaagaacag
    17521 tctctgtata ggtctggcta tctttattgg gaacacttgt aaagagtaca gtctttgccc
    17581 ccatctcctt ggcatctaat agactatcta aaatagaagg agttgagcct gaaagtgaga
    17641 aacccagtac tagacaattt tcatccatga tgctggttgt ccaggcaaag ccgtcttggt
    17701 ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg taatttcatt tcacgggcga
    17761 cgaggccaga actccctgtt ccaaagaagt agatacgctc agcatcttcg attagctggg
    17821 caattcgctc tagttggatt tcgtcaatca agtcttgtgt ttgttccctc atattgctat
    17881 aacttctgag gactcgtttg gtcagtggac tatgcttgga gacttggttg gcttgatttt
    17941 ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc agtaaagcca cactttttag
    18001 caaagcgggt caaagcagct tgagaaatat gtaatttttg ggtgacttgt tgagaagata
    18061 aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc gatttcttgc tctaggtctg
    18121 tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc tggtttgtcc atagggaaag
    18181 ctcctttaca tgggtcatac tggaagacta gatcagggaa tagtcacact tcattataac
    18241 acataatata aggatagata aataaaaacg catctctgtt ttaaaaacga aaaaatcgaa
    18301 aaagcttctc tcttttccat aattttctac tcaaattgtg gtacaattaa gagtaagatt
    18361 ttaagttaga aatgagactg atttgtatga gaaaatttaa cagccattcg attccgattc
    18421 ggcttaattt attgttttca atcgtcattt tactctttat gaccattatt ggtcgtttgt
    18481 tgtatatgca ggttttgaac aaggattttt acgaaaaaaa gctagcctca gctagtcaga
    18541 ccaagattac aagcagttca gcccgtgggg aaatttatga tgctagtgga aaacctttgg
    18601 tagaaaatac gttaaagcag gttgtttcct ttacgcgtag caataaaatg acggctacag
    18661 acttaaaaga aacagctaaa aagttactga cttatgtgag catcagttct ccaaatttga
    18721 cagaacgcca gctggcggat tactatttgg ctgatcctga aatctataaa aaaacagtgg
    18781 aagctctccc aagtgagaaa cgcttggatt cagatggcaa tcgtctatcc gaatcagaac
    18841 tgtataacaa tgcggtcgat agtgtccaaa caagtcaact aaactataca gaggatgaaa
    18901 agaaagaaat ctatcttttt agtcagttaa atgctgttgg aaactttgcg acaggaacca
    18961 ttgctacaga tcctctaaat gattctcagg tggctgttat tgcctctatt tcaaaggaga
    19021 tgcctggcat tagtatttct acttcttggg atagaaaggt tttggaaact tccctttctt
    19081 ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc agcggaagaa gcagaagcct
    19141 atcttaaaaa aggctattct ctaaatgatc gtgtaggaac ctcctatttg gaaaagcaat
    19201 atgaagagac cttacaagga aaacgctcgg taaaagaaat ccatctggat aaatatggca
    19261 atatggaaag cgtggataca attgaggaag gtagtaaggg aaacaatatc aaactgacca
    19321 ttgatttggc tttccaagat agcgtggatg ctttactgaa aagttatttc aattccgagc
    19381 tagaaaatgg tggagccaag tattctgaag gtgtctatgc agtcgccctt aacccaaaaa
    19441 caggtgcggt tttgtctatg tcagggatta aacatgactt gaaaacggga gagttgacgc
    19501 ctgattcctt gggaacggta accaatgtct ttgttccagg ttcggttgtc aaggcggcga
    19561 ccatcagctc aggttgggaa aatggagtct tgtcaggaaa ccagaccttg acagaccagt
    19621 ccattgtctt ccaaggttca gctcccatca attcttggta tactcaggct tacggttcat
    19681 tccctatcac agcggtccaa gctctggagt attcatcaaa tacctatatg gtccaaacag
    19741 ccttaggtct tatggggcaa acctatcaac ccaatatgtt tgtcggcacc agcaatctag
    19801 agtctgctat ggagaaactg cgttcaacct ttggcgaata tggcttgggt actgcgacag
    19861 gaattgacct accagatgaa tctactggat ttgttcccaa agagtatagc tttgctaatt
    19921 acattactaa tgcctttggg cagtttgata actatacgcc gatgcagttg gctcagtatg
    19981 tagcaactat tgcaaataat ggtgttcgtg tggctcctcg tattgttgaa ggcatttatg
    20041 gtaataatga taagggagga ctgggtgact tgattcagca actgcaaccg acagagatga
    20101 ataaggtcaa tatatccgac tccgatatga gcatcttgca ccaaggtttt tatcaggttg
    20161 cccatggtac tagtggattg acaactggac gtgccttttc aaatggcgcc ttggtatcca
    20221 ttagcggaaa aacaggtaca gccgaaagct atgtggcaga tggtcagcaa gcaaccaata
    20281 ccaatgcggt ggcctatgcc ccatctgata atccccaaat cgctgttgca gtggtctttc
    20341 ctcataatac caatctaaca aatggtgtag gaccttccat tgcgcgtgac attatcaatc
    20401 tgtatcaaaa ataccatcca atgaactaga aaggaaatta tgctttatcc aacacctatt
    20461 gccaagttga ttgacagtta ttctaagtta ccaggtatcg ggattaagac ggctacgcgt
    20521 ctggcctttt atacgattgg gatgtctgct gatgatgtca atgaatttgc aaaaaatctc
    20581 ctttctgcta agagagaatt gacatattgt tctatttgtg gacgtttgac agacgacgat
    20641 ccttgttcta tctgtactga tccgactcgt gaccagacaa caattttagt tcttgaggat
    20701 agtagagatg tggcagccat ggaaaatatc caagaatacc atggactcta tcatgtcctt
    20761 catggcctca tttctcctat gaatggtatc agtccggacg atatcaatct caagagcctt
    20821 atgactcgtc ttatggatag tgaagtttca gaagtgattg tggcgactaa tgctacagcg
    20881 gatggtgaag cgacttccat gtatctttca cgtttgctca agccggctgg tatcaaggtt
    20941 acgcgtctag cacgaggtct cgctgtggga gcggacattg agtatgcgga cgaagtgaca
    21001 ctcttacgag cgattgaaaa tcggacagag ttgtaagtgt aggcaaattt acgaactcca
    21061 ttcatttata aaaaatcaaa gaggctgaaa atcgttccta tcggcctctt tttgtatagt
    21121 gtgatgagta ggatcaggtt caagttttaa aaaaccaagc aaatatgata tactaaagag
    21181 cgagtattct agtagaatta ggacaaataa tatgaaacaa acgattattc ttttatatgg
    21241 tggacggagt gcggaacgcg aagtctctgt cctttcagct gagagtgtca tgcgtgcggt
    21301 caattacgac cgtttcacag tcaagacttt ctttatcagt cagtcaggtg actttatcaa
    21361 aacacaggaa tttagtcatg ctccggggca agaagaccgt ctcatgacca atgaaaccat
    21421 tgattgggat aagaaagttg caccaagtgc tatctacgaa gaaggtgcag tggtctttcc
    21481 agtccttcac gggccaatgg gagaagatgg ctctgttcaa ggattcttgg aagttttgaa
    21541 aatgccttac gttggttgca acattttgtc atcaagtctt gccatggata aaatcacgac
    21601 taagcgtgtt ctggaatctg ctggtattgc ccaagttcct tatgtggcta tcgttgaagg
    21661 cgatgatgtg actgctaaaa tcgctgaagt ggaagaaaaa ttggcttatc cagtcttcac
    21721 taagccgtca aacatggggt ctagtgtcgg tatttctaag tctgaaaacc aagaagaact
    21781 ccgtcaagcc ttaaaacttg ccttccgata tgacagccgt gtcttggttg agcaaggagt
    21841 gaatgcccgt gaaattgagg ttggcctctt gggtaactac gatgtcaaga gcacgctacc
    21901 tggagaagtt gtcaaggacg ttgcctttta tgactacgat gccaagtata ttgataacaa
    21961 gattactatg gatattcctg ccaaaatcag tgatgatgtg gtggctgtca tgcgtcaaaa
    22021 tgcagaaaca gccttccgtg ccattggtgg ccttggtcta tctcgttgcg atttcttcta
    22081 tacagataag ggagagattt ttctcaacga gctcaatacc atgccaggtt ttacccagtg
    22141 gtctatgtac ccactacttt gggacaatat ggggatcagc tacccagaac taatcgagcg
    22201 tttggttgac cttgccaagg aaagttttga caagcgcgaa gcgcatttga tataaaatga
    22261 aagagagggt agaagccaga accatcactg cacggtgact agagttctcg gacttcagcc
    22321 ctttttaaag gagtagaaat gaaattaaca atccatgaaa ttgcccaagt tgttggagcc
    22381 aaaaatgata tcagtatctt tgaggacacc cagttagaaa aagctgagtt tgatagtcgt
    22441 ttgattggaa ctggagattt atttgtgcca cttaaaggtg cgcgtgatgg ccatgacttt
    22501 attgaaacag cctttgaaaa tggtgcagca gtaaccttgt ctgagaaaga ggtctcaaat
    22561 catccttaca ttctagtaga tgatgttttg acagcctttc aatccctagc atcctactat
    22621 cttgaaaaaa cgactgttga tgtctttgct gttacaggtt caaatggcaa gacaacgact
    22681 aaggatatgt tggcgcattt actgtcaaca agatacaaga cctacaaaac acaaggcaat
    22741 tacaataatg agattggcct tccttacaca gttcttcata tgcctgaagg aacagaaaag
    22801 ttggttttgg agatgggaca ggatcacttg ggagatattc atctcttgtc tgaattggct
    22861 cgtccaaaaa cagccatcgt gaccttggtt ggagaagctc atttggcctt tttcaaagat
    22921 cgttctgaga ttgctaaagg aaaaatgcaa attgcagacg gaatggcttc aggttccttg
    22981 cttttagcgc cggctgaccc tatcgtagag gactatttgc caactgataa aaaggtggtt
    23041 cgttttggtc aaggagcaga gctgggaatt accgacttgg ttgagcgcaa agatagtctg
    23101 accttcaagg tcaatttctt agagcaagcc cttgatttgc cagtaactgg caagtacaat
    23161 gcgacaaatg ctatgattgc atcctatgtt gccttgcaag aaggagtttc agaggagcaa
    23221 attcgtttgg ccttccaaca tcttgaattg acgcgtaacc gtaccgagtg gaagaaagca
    23281 gccaatggag cagatatcct gtcagatgtt tataatgcca atccaactgc tatgaaactg
    23341 attttagaga ctttctctgc cattccagcc aatgaaggtg gcaagaaaat tgcagtgttg
    23401 gcggatatga aggagcttgg tgaccagtct gttcaacttc ataatcagat gattttgagc
    23461 ctctccccag atgtgcttga tatcgttatt ttctatggag aagatattgc tcagttggct
    23521 caattggcca gtcaaatgtt tccaatcggc cacgtttact acttcaagaa aacagaagac
    23581 caggatcaat ttgaagacct agtcaagcag gttaaggaaa gccttggagc ctatgaccaa
    23641 atcttgctaa aaggttctaa ctctatgaat ctagccaaat tggtagaacg tttagaaaat
    23701 gaagccaagt gattttgtca agtatctgca aagaatgatt gcccttacag atactggctt
    23761 aacctttaca aaagatcctt ttgaccgtga gcgctacgag gacttgcgaa gtctgttatc
    23821 tgaaatgttg aatcagggat cagacctgga tgcagaagaa gtagcagaag tcttgaaacc
    23881 aacttcagct tatgcgactc ccttaatgga cgtccgtgct tggattgttg aggatgagaa
    23941 gatttgtctg gttaggggac aaggagagga tagttgggct ttgccaggtg gctttggtga
    24001 agtcggctat tctccaactg aaaatattct caaggaaatt gaagaagaaa ccggttttaa
    24061 agccaaagtt gaaagactgc tagctgtttt tgataccaat cgtttccaac tacagagtaa
    24121 acaatatgca aagtttgttt ttgaatgtaa gtttctcgat ggacaattcc aagaaaatca
    24181 agaaattgca gaccttcaat tttttgccat tgatcaactg ccagccttat ctgaaaaacg
    24241 cattaccaag gagcaaatcg agattctttg gcaggtttat caaggtcaga gggagcaata
    24301 tcttgactaa gaagatgatt atcgtatttt taaatccatt tttaacaact agcatggtat
    24361 aataatatgc aggaaaattt tgaattatga ggaagactag atgaatttat gggatatttt
    24421 ctttacgact caggcaaccg agccgcccaa atttgacctt ttttggtatg ttagcctatt
    24481 tacgctctta gccttaacct tttatacagc ccatcgctat cgtgaaaaga aggtttacca
    24541 acgatttttc caaatcttgc agactgttca gttaatcctt ctttatggtt ggtactgggt
    24601 caatcatatg ccactgtcag aaagcctacc cttttaccat tgccgtatgg ctatgtttgt
    24661 ggtactcttg cttcctggtc agtccaaata taaacaatac tttgcattat tgggaacatt
    24721 tgggacatta gcagcctttg tttatccagt gccagatgct tacccttttc cacatatcac
    24781 cattctatcc tttatctttg gtcatttagc actcttgggg aactctctag tttatctatt
    24841 gagacagtat aatgcgcgat tgctggatgt gaagggaatt tttctcatga cctttgccct
    24901 aaatgccttg atttttgtgg tcaatttggt gacaggtggc gattacggat ttttgacaaa
    24961 accgccattg gttggggatc acggtctagt agctaattat ttacttgttt caattgtgct
    25021 ggtagctact atcagtttga ctaagaaaat cttagaattc tttttagctc aagaagcaga
    25081 aaaaatgatt gcaaaggaag cttaacacag agctttcttt tttgctctta gagagttttt
    25141 acaagcagct tataaaataa gaatttctga atagacaaac tcaaaaaatg gctgggaaat
    25201 ttaggaaaaa agcaagcacg attaaatttt ttgtgttata atattttgtg aatagctatg
    25261 cctatgttta gctatggaat aatacgaagt gcgaaacttg gaagatagag aggaagcgat
    25321 gtaatggcta gagaaggctt ttttacaggt ctagatattg gaacaagctc tgtcaaggtg
    25381 cttgtggccg agcagagaaa tggtgaatta aatgtaattg gcgtgagtaa tgccaaaagt
    25441 aaaggtgtaa aggatggaat tattgttgat attgatgcag cagcaactgc tatcaagtca
    25501 gccatttccc aagcggaaga aaaggcaggc atttcgatta aatcagtgaa tgtcggcttg
    25561 cctggtaatc ttttgcaggt agaaccaact caggggatga ttccagtaac atctgatact
    25621 aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat cagctttgac aaagagtatg
    25681 acacctgacc gtgaagtcat tacctttatt cctgaagaat ttattgtgga tggtttccaa
    25741 gggattcgtg acccacgtgg tatgatgggg gttcgccttg aaatgcgtgg tttgctttat
    25801 acaggacctc gtactatctt gcacaatttg cgtaagacgg ttgagcgtgc aggtgttcag
    25861 gttgaaaatg ttatcatttc accactagca atggttcagt ctgttttgaa cgaaggggaa
    25921 cgtgaatttg gtgctacagt gattgatatg ggggcaggtc aaacgactgt cgctacaatc
    25981 cgtaatcaag aactccagtt cacacatatt ctccaagaag gtggagatta tgtaactaaa
    26041 gatatctcca aggttttgaa aacctctcgc aaattagcgg aaggcttgaa actgaattac
    26101 ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc aagtagaggt tattggagaa
    26161 gtggaagcag tcgaagtgac ggaagcctac ttgtcagaaa ttatttctgc acgaatcaag
    26221 cacatccttg aacaaatcaa gcaagaatta gatagaaggc gtctattgga cctccctggt
    26281 ggtattgtct taatcggtgg gaatgccatt ttaccaggta tggttgagct tgctcaggaa
    26341 gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag ttggtatccg taatccagcc
    26401 tttgcgcatg tgattagttt atcagaattt gcgggtcaat taacagaagt taatcttttg
    26461 gctcagggag cgataaaagg tgagaatgac ttaagtcatc agccaattag ttttggtggg
    26521 atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg ttcaaccagc tcctgctcca
    26581 gaagtagagc cggtggcgcc tacagaacca atggcggatt tccaacaagc ttcacaaaat
    26641 aaaccgaaat tagcagatcg tttccgtggc ttgatcggaa gcatgtttga cgaataaaga
    26701 ggaaaaataa attatgacat tttcatttga tacagctgct gctcaagggg cagtgattaa
    26761 agtaattggt gtcggtggag gtggtggcaa tgccatcaac cgtatggtcg acgaaggtgt
    26821 tacaggcgta gaatttatcg cagcaaacac agatgtacaa gcattgagta gtacaaaagc
    26881 tgagactgtt attcagttgg gacctaaatt gactcgtggt ttgggtgcag gaggtcaacc
    26941 tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca ctgacggaag ctattagtgg
    27001 tgccgatatg gtcttcatca ctgctggtat gggaggaggc tctggaactg gagctgctcc
    27061 tgttattgct cgtatcgcca aagatttagg tgcgcttaca gttggtgttg taacacgtcc
    27121 ctttggtttt gaaggaagta agcgtggaca atttgctgta gaaggaatca atcaacttcg
    27181 tgagcatgta gacactctat tgattatctc aaacaacaat ttgcttgaaa ttgttgataa
    27241 gaaaacaccg cttttggagg ctcttagcga agcggataac gttcttcgtc aaggtgttca
    27301 agggattacc gatttgatta ccaatccagg attgattaac cttgactttg ccgatgtgaa
    27361 aacggtaatg gcaaacaaag ggaatgctct tatgggtatt ggtatcggta gtggagaaga
    27421 acgtgtggta gaagcggcac gtaaggcaat ctattcacca cttcttgaaa caactattga
    27481 cggtgctgag gatgttatcg tcaacgttac tggtggtctt gacttaacct tgattgaggc
    27541 agaagaggct tcacaaattg tgaaccaggc agcaggtcaa ggagtgaaca tctggctcgg
    27601 tacttcaatt gatgaaagta tgcgtgatga aattcgtgta acagttgtcg caacgggtgt
    27661 tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct agaactgcta ctaactaccg
    27721 tgagacagtg aaaccagctc attcacatgg ctttgatcgt cattttgata tggcagaaac
    27781 agttgaattg ccaaaacaaa atccacgtcg tttggaacca actcaggcat ctgcttttgg
    27841 tgattgggat cttcgccgtg aatcgattgt tcgtacaaca gattcagtcg tttctccagt
    27901 cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa ttggatacac ctccattttt
    27961 caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga acttgttttt cgagaagttg
    28021 cagaggctag tctgagtgct catcgagaga gtggttcggt ctctgtcatt gcagttacca
    28081 agtatgtaga tgtaccgaca gcggaagcct tgcttccgct aggtgttcat catatcggtg
    28141 aaaatcgtgt agataagttt ctggaaaaat atgaagcttt aaaagatcga gatgtgactt
    28201 ggcatttgat tggtaccttg caaagacgta aggtgaaaga tatcattcaa tacgttgatt
    28261 atttccatgc attggactca gtaaagctag caggggaaat tcaaaaaaga agtgaccgag
    28321 tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga aagcaaacac ggtttttcga
    28381 gagaggaact gctggaaatc ttgccagagt tagccagact agataagatt gaatatgttg
    28441 gtttaatgac gatggcacct tttgaggcta gcagtgagca gttgaaagag attttcaagg
    28501 cgacccaaga tttacaaaga gaaattcaag agaaacaaat tccaaatatg cctatgaccg
    28561 agttaagtat gggaatgagt cgtgattata aagaagcgat tcaattcggt tccacttttg
    28621 ttcgtatagg tacatcattt tttaagtagg agagaaccat gtctttaaaa gatagattcg
    28681 atagatttat agattatttt acggaggatg aggattcaag tctcccttat gaaaaaagag
    28741 atgagcctgt gtttactcca gtaaattctt cacaggaacc ggctctccca atgaatcaac
    28801 cttcacagtc ggctggtaca aaagagaaca atatcaccag acttcatgca agacaacagg
    28861 aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat tatagatgtt cgttatccta
    28921 gaaaatatga ggatgcaaca gaaattgttg atttattggc aggaaacgaa agtatcttga
    28981 ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg tttggactat ttggatggag
    29041 cttgtcatgt tttagctgga aatttgaaaa aggtagcttc taccatgtat ttgttgacac
    29101 cagtgaatgt tattgtaaat gttgaagata tccgtttacc agatgaagat caacagggtg
    29161 agttcggttt tgatatgaag cgaaatagag tacgataatg atttttttaa ttcgtatgat
    29221 ttataatgca gtggatattt actccctgat tttggtagcc ttcgctgtca tgtcttggtt
    29281 tccaggtgcc tacgaatcca gtttaggtcg ttggattgta gcgttggtga aaccagtgct
    29341 tgctcccttg caacgcctgc ctttacagat agcgggtctt gatttatctg tttgggtcgc
    29401 gattgttttg gttcgatttt taggagaaaa cctagtgcgt tttctggcga tgataggatg
    29461 aataaaggga tttatcagca tttctccata gaagatcgtc catttcttga caagggaatg
    29521 gaatggataa agaaggtaga agatagctat gctccttttt taactccttt tatcaatcct
    29581 catcaggaga agctattaaa gattttggcc aaaacctatg gtcttgcttg tagcagtagt
    29641 ggggaattcg tctcgagtga gtatgttcga gttttattat acccagatta tttccaacca
    29701 gagttttcag attttgaaat atctctccag gaaattgtgt attccaataa atttgaacat
    29761 ttaacgcatg ctaagatttt agggacagtc atcaatcaat tagggattga acggaaactt
    29821 tttggagata tcctagtaga tgaagaacgg gcgcagatta tgattaatca gcagtttctt
    29881 cttctctttc aagatggact aaagaaaatt ggtcgtatac ctgtttcgct ggaggaacgt
    29941 cctttcaccg agaaaataga taagctagaa cagtatcgag aactggattt atctgtgtct
    30001 agttttcgat tagatgttct tttatcaaat gttttgaaac tatctaggaa tcaagcaaac
    30061 cagttgattg aaaagaaact tgtccaagta aattatcatg tggtagacaa atcagattac
    30121 actgttcaag ttggagactt gattagtgtg agaaaatttg gtcgcttgag attacttcaa
    30181 gataagggac aaacgaaaaa agagaagaaa aaaataaccg tccagttatt attaagtaag
    30241 tgaggaatag aatgccaatt acatcattag aaataaagga caagactttt ggaactcgat
    30301 tcagaggttt tgatccagaa gaagtcgatg aatttttaga tattgtggtt cgtgattacg
    30361 aagatcttgt gcgtgcgaat catgataaaa atttgcgtat taagagttta gaagagcgtt
    30421 tgtcttactt tgatgaaata aaagattcat tgagccagtc tgtattgatt gctcaggata
    30481 cagctgagag agtgaaacag gcggcgcatg aacgttcaaa caatatcatt catcaagcag
    30541 agcaagatgc gcaacgcttg ttggaagaag ctaaatataa ggcaaacgag attcttcgtc
    30601 aagcaactga taatgctaag aaagtcgctg ttgaaacaga agaattgaag aacaagagcc
    30661 gtgtcttcca ccaacgtctc aaatctacaa ttgagagtca gttggctatt gttgaatctt
    30721 cagattggga agatattctc cgtccaacag ctacttatct tcaaaccagt gatgaagcct
    30781 ttaaagaagt ggttagcgaa gtacttggag aaccgattcc agctccaatt gaagaagaac
    30841 caattgatat gacacgtcag ttctctcaag cagaaatgga agaattacaa gctcgtattg
    30901 aggtagccga taaagaattg tctgaatttg aagctcagat taaacaggaa gtggaaactc
    30961 caactcctgt agtgagtcct caagttgaag aagagcctct gctcatccag ttggcccaat
    31021 gtatgaagaa ccagaagtag ctccagtgca tccgacaggt ccaacaccag ctacagaaac
    31081 tgttgattca gcaccaggat ttgaagcacc gcaagaatcc gttacaattt tataagaaac
    31141 gatgtgagaa caatatctta tccttatatt tccagcgagc aggagatggt gtgagtcctg
    31201 cattccctaa cgataagatt atcctctcaa aaactcaagt ctgaatctag taagatttga
    31261 cgtttcccac gttacgggat aagagggaga aagactaaat ctttttccga ataaaggtgg
    31321 taccacgatt ttcgtccttt ttggaagtcg tggtttttaa tttgttatta tttataaagg
    31381 agataccatg aaactaaaag atacccttaa tcttgggaaa acagctttcc caatgcgtgc
    31441 aggccttccg accaaagagc cagtttggca aaaggaatgg gaagatgcaa aactttacca
    31501 acgtcgtcaa gaactaaatg aagggaaacc gcattttgtc ttgcatgatg gccctccata
    31561 cgcaaacgga aatatccacg ttggacatgc catgaatcat atctcaaaag atatcatcat
    31621 tcgttctaag tctatgtcag gttttaacgc accttatatc ccaggttggg atactcatgg
    31681 tctgccaatc gagcaagttt tggcaaagca aggtgtgaag cgcaaagaaa tggacttggt
    31741 tgagtacttg aaactttgcc gtgaatacgc tctttctcaa gtttataaac aacgtgatga
    31801 tttcaagcgc ttggggatgt caggtgactg ggaaaattta tatgtgactt taactccaga
    31861 ctacgaagca gcccaaatcc gtgtatttgg tgagatggct aataagggtt atatctaccg
    31921 tggtgctaag ccagtttact ggtcttggtc atctgagtca gcccttgccg aagcggaaat
    31981 tgaataccat gatttggttt caacttccct ttactatgcc aataaggtaa aagatggcaa
    32041 aggtgttcta gatacagata cttatatcgt tgtttggaca actactccat ttactatcac
    32101 agcttctcgt ggtttgactg ttggtgcaga tattgattac gttttggttc aacctgctgg
    32161 tgaaactcgt aagtttgtcg ttgctgcaga attgttgact agcttgtctg agaaatttgg
    32221 ctgggttgat gttcaagttt tggcaactta ccgtggtcaa gaactcaacc acatcgtaac
    32281 agaacatcca tgggatacag ctgtagatga attggttatc cttggtgacc acgttacaac
    32341 tgactctggt acaggtattg tccatacagc ccctggtttt ggtgaggacg attacaatgt
    32401 tggtattgct aataatcttg aagtcgcagt gactgttgat gaacgtggta tcatgatgaa
    32461 gaatgctggt cctgaatttg aaggtcaatt ctatgaaaag gtagttccaa ctgttattga
    32521 aaaacttggt aacctccttc ttgcccaaga agaaatctct cactcatatc catttgactg
    32581 gcgtaccaag aaaccaatta tctggcgtgc agtaccacag tggttcgcct ctgtttcaaa
    32641 attccgccaa gaaatcttgg atgctattga taaagttaaa ttccatacag aatggggtaa
    32701 agtacgtcta tataatatga ttcgtgaccg tggtgactgg gttatctctc gtcaacgtgc
    32761 ttggggtgtt ccacttccaa tcttctatgc agaagacggt acagctatca tgacagctga
    32821 gactatcgaa tatgtggctc aactctttga agtacatggt tcaagcattt ggtgggaacg
    32881 tgatgccaaa gacctcttgc cagaaggatt tacacatcca ggttctccaa atggcgagtt
    32941 caaaaaagaa actgatatca tggacgtttg gtttgactca ggttcatcat ggaatggtgt
    33001 tttggtaaat cgtccaaatc tgacttatcc agctgacctt taccttgaag gttctgacca
    33061 ataccgtggt tggttcaact catcactcat tacatctgtt gccaaccatg gcgtagcacc
    33121 ttacaaacaa atcttgtcac aaggttttac ccttgacggt aaaggtgaga agatgtctaa
    33181 atctcttgga aataccattg ctccaagcga tgttgaaaaa caatttggtg ctgaaatctt
    33241 gcgtctctgg gtaacaagtg ttgactcaag caatgacgtg cgtatctcta tggatatctt
    33301 gagccaagtc tctgaaactt accgtaagat tcgtaatact cttcgtttct tgattgccaa
    33361 tacatctgac tttaacccaa ctcaagatgc agtcgcttac gatgaacttc gttcagttga
    33421 taagtacatg accattcgct ttaaccagct tgtcaagacc attcgtgatg cctatgcaaa
    33481 ctttgaattc ttgacaatct acaaggcctt ggtgaacttt atcaacgttg atttatcagc
    33541 cttttacctt gattttgcta aagatgttgt ttacatcgaa ggtgctaaat cactggaacg
    33601 tcgtcaaatg cagactgtct tctatgatat tcttgtcaaa atcaccaaac tcttgacacc
    33661 aatccttcct cacactgcgg aagaaatctg gtcatatctt gagtttgaaa cagaagactt
    33721 cgtccaattg tcagaattac cagaagttca aacttttgct aaccaagaag aaatcttgga
    33781 tacatgggca gccttcatgg actttcgtgg acaagcacaa aaagccttgg aagaagctcg
    33841 taatgcaaaa gttatcggta aatcacttga agcacacttg acagtttatc caaatgaagt
    33901 ggtgaaaact ctactcgaag cagtaaatag caatgtggct caacttttga tcgtgtctga
    33961 gttgaccatc gcagaaggac cagctccgga agctgccctt agcttcgaag atgtagcctt
    34021 cacagttgaa cgtgctgctg gtgaagtatg tgaccgttgc cgtcgtattg acccaacaac
    34081 agcagaacgt agctaccagg cagttatctg tgaccactgt gcaagcatcg tagaagaaaa
    34141 ctttgcggaa gcagtcgcag aaggatttga agagaaataa gattgaaaag tctaggcaaa
    34201 attcaatttg agaagaaaag acaactaatt ttatagtcta ttaaacgcat tgtatcacgt
    34261 ttttgaacac ctgatatgat gcgtttttta tttattttaa aaatttgcga ggtatgactt
    34321 tttatactca acaagaatca aagagaaact tagcaagcta acagtagtaa gataaaatag
    34381 gaatttgata ttaggga
//
LOCUS       DAVKUR010000019        34138 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKUR010000019 DAVKUR010000000
VERSION     DAVKUR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.019"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..171)
                     /locus_tag="VW749_001010"
     CDS             complement(<1..171)
                     /locus_tag="VW749_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0175058.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQK"
     gene            complement(353..589)
                     /locus_tag="VW749_001011"
     CDS             complement(353..589)
                     /locus_tag="VW749_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175059.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(602..1075)
                     /locus_tag="VW749_001012"
     CDS             complement(602..1075)
                     /locus_tag="VW749_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175060.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(1093..1278)
                     /gene="briC"
                     /locus_tag="VW749_001013"
     CDS             complement(1093..1278)
                     /gene="briC"
                     /locus_tag="VW749_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0175061.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1437..2204)
                     /locus_tag="VW749_001014"
     CDS             complement(1437..2204)
                     /locus_tag="VW749_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0175062.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(2201..3067)
                     /locus_tag="VW749_001015"
     CDS             complement(2201..3067)
                     /locus_tag="VW749_001015"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0175063.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(3104..4471)
                     /gene="accC"
                     /locus_tag="VW749_001016"
     CDS             complement(3104..4471)
                     /gene="accC"
                     /locus_tag="VW749_001016"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0175064.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4483..4905)
                     /gene="fabZ"
                     /locus_tag="VW749_001017"
     CDS             complement(4483..4905)
                     /gene="fabZ"
                     /locus_tag="VW749_001017"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0175065.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4902..5387)
                     /locus_tag="VW749_001018"
     CDS             complement(4902..5387)
                     /locus_tag="VW749_001018"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0175066.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5390..6625)
                     /gene="fabF"
                     /locus_tag="VW749_001019"
     CDS             complement(5390..6625)
                     /gene="fabF"
                     /locus_tag="VW749_001019"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0175067.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6647..7378)
                     /gene="fabG"
                     /locus_tag="VW749_001020"
     CDS             complement(6647..7378)
                     /gene="fabG"
                     /locus_tag="VW749_001020"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0175068.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7412..8332)
                     /gene="fabD"
                     /locus_tag="VW749_001021"
     CDS             complement(7412..8332)
                     /gene="fabD"
                     /locus_tag="VW749_001021"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0175069.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8325..9299)
                     /gene="fabK"
                     /locus_tag="VW749_001022"
     CDS             complement(8325..9299)
                     /gene="fabK"
                     /locus_tag="VW749_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0175070.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9418..9642)
                     /locus_tag="VW749_001023"
     CDS             complement(9418..9642)
                     /locus_tag="VW749_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0175071.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9702..10676)
                     /locus_tag="VW749_001024"
     CDS             complement(9702..10676)
                     /locus_tag="VW749_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0175072.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10676..11110)
                     /locus_tag="VW749_001025"
     CDS             complement(10676..11110)
                     /locus_tag="VW749_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0175073.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(11204..11989)
                     /locus_tag="VW749_001026"
     CDS             complement(11204..11989)
                     /locus_tag="VW749_001026"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0175074.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12358..13722
                     /locus_tag="VW749_001027"
     CDS             12358..13722
                     /locus_tag="VW749_001027"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0175075.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13725..14096
                     /locus_tag="VW749_001028"
     CDS             13725..14096
                     /locus_tag="VW749_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0175076.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14310..15584
                     /gene="serS"
                     /locus_tag="VW749_001029"
     CDS             14310..15584
                     /gene="serS"
                     /locus_tag="VW749_001029"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0175077.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(15609..16508)
                     /locus_tag="VW749_001030"
     CDS             complement(15609..16508)
                     /locus_tag="VW749_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0175078.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16618..17166)
                     /locus_tag="VW749_001031"
     CDS             complement(16618..17166)
                     /locus_tag="VW749_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0175079.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17384..18706)
                     /locus_tag="VW749_001032"
     CDS             complement(17384..18706)
                     /locus_tag="VW749_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0175080.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18797..18885)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(19049..21385)
                     /locus_tag="VW749_001033"
     CDS             complement(19049..21385)
                     /locus_tag="VW749_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0175081.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21489..22037)
                     /locus_tag="VW749_001034"
     CDS             complement(21489..22037)
                     /locus_tag="VW749_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0175082.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(22034..22336)
                     /gene="zapA"
                     /locus_tag="VW749_001035"
     CDS             complement(22034..22336)
                     /gene="zapA"
                     /locus_tag="VW749_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0175083.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22423..23307
                     /locus_tag="VW749_001036"
     CDS             22423..23307
                     /locus_tag="VW749_001036"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0175084.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            23319..23933
                     /gene="lepB"
                     /locus_tag="VW749_001037"
     CDS             23319..23933
                     /gene="lepB"
                     /locus_tag="VW749_001037"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0175085.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            24061..26427
                     /locus_tag="VW749_001038"
     CDS             24061..26427
                     /locus_tag="VW749_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0175086.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26475..27758)
                     /locus_tag="VW749_001039"
     CDS             complement(26475..27758)
                     /locus_tag="VW749_001039"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0175087.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28602..29738)
                     /locus_tag="VW749_001040"
     CDS             complement(28602..29738)
                     /locus_tag="VW749_001040"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0175088.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29800..30237)
                     /locus_tag="VW749_001041"
     CDS             complement(29800..30237)
                     /locus_tag="VW749_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0175089.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(30239..32194)
                     /locus_tag="VW749_001042"
     CDS             complement(30239..32194)
                     /locus_tag="VW749_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0175090.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(32218..33987)
                     /locus_tag="VW749_001043"
     CDS             complement(32218..33987)
                     /locus_tag="VW749_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0175091.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10116 a         7668 c         6440 g         9914 t
ORIGIN      
        1 tttttgaaag tcatatttct tcatttgact tccgcactca gggcaagatg gggcgtcgta
       61 gtccagtttg gcgatgattt ctttgtgtgt atccttattg atgatatcta gaatcttgat
      121 gtttgggtct ttaatgtcta gtaattttgt gataaaatgt aattgttcca tatgaatctt
      181 tctaatgagt tgttttgtcg cttttcatta taggtcatat gggacttttt ttctacacaa
      241 aaataggctc cataatatct ataggggatt tacccactac aaatattata gagccaacaa
      301 taaaaagaaa aagtgtttga tagatatcaa acactttttt ctttgcctcc cactatctaa
      361 aaaaatgata atagatataa ttgtaaacaa aaatccagat aggttttgca tgattgagaa
      421 agttaaaaaa actatggcag agaatcgtta atctcagatt gtcggtagaa cgataaacaa
      481 gggcaaaaaa gaaaccaatc agactataat ataataaact aattggatct ctgtgagata
      541 gtatcaaatg gctaatccca aagatgatag cagataggat aacatccaaa tagtacttgg
      601 actagggaaa gaaggtattc ataaaatacc ctctatcaag agtctcctca aaaacaggac
      661 cgatgattac aggcaggaca aaagataaga tagtcgataa aaaggttggt tgtccatttg
      721 aaaaaagcac ggtaaaatac tcatcatgaa tattcctatg attaatcaaa tgagcatagc
      781 gtgcccaaaa attaccgaga atctgataaa ccacataagt tgcaaataag tagaagacaa
      841 atgaccagtt ccagctcttt ttctcaaaga taaagagcat ctttttcttt tttaacctcc
      901 aaattaatag aaggaaactt cccactaatc ccattgttaa aataagagaa tagacatcag
      961 ctcctaaccc taaaatgatc gtcacataca atccaattgt ttgtggtaaa taggtagata
     1021 gtaaaataat aagcaaaaat attccaaatt gtcttagttt ttttgtgttt ctcatcgtac
     1081 ttttttgaaa gattaccctg ctcggaagcc gtacttccaa gcatctatat aagaattaag
     1141 tgccccttgc ctcatatagg gagcaaattc tctataatat aaccatctac tatatccatc
     1201 ttcccaaaca gcaagaccac ctgaagtttg ctccaagtcc tcagttgaaa gaactgtaaa
     1261 tgtatttgta cctgtcattg caagtacctt cttaaaatag attgttgtag gctcacattt
     1321 atagtatatt tctttttttg tctattttat agcccatctc ctcaactggc aatttttcga
     1381 cctgaattac atttttccat aaaaaatgag acctttctag tctcatttag tcattcttag
     1441 tattttctaa atcgttgata gcgttcttcc agcaactctt ctagcggttt ttgtgaaagt
     1501 ctagccagct ccgtttggag ttcttttttg acactcttaa tcagttcttt actagaaagt
     1561 cctatttcag aaatcacctt atccaccacg tccatttcta acagttcatg cgaagtgatt
     1621 ttcatcagtt ctgctgcttc catggcgcga gtaccgtcct tccataaaat ggaagcaaag
     1681 ccttctggac tgagaatggc atagatagaa ttttccagca tccagacacg gtccgcgaca
     1741 gctagagcca gagccccgcc tgaaccacct tcaccgataa taatggcgat aataggaact
     1801 ttcaggtcac tcatttccat gagattgcga gcgatagctt ccccttgacc acgttcttcc
     1861 gctccgacac caggataagc acctgctgta ttgataaagg tcacaactgg acggccaaat
     1921 ttctcagcat gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg tggttggcca
     1981 aaattccgtt tgaggttgtc ttgcaaactc ttgccttttt ggataccaac cactgttaca
     2041 gcttgatctc caagccaacc aataccacca acaactgcac catcatcacg aaaagaacgg
     2101 tcaccatgta attggataaa ttcatcaaaa atgcctgtcg caaagtccaa ggttgtcaag
     2161 cgactctgct cacgcgcttc tctgactatt tttgcaatat tcatctagga ctccctccat
     2221 gcaatctgac taggctagca atcgtatctg gtaagtctct tcttttgaca atagcatcca
     2281 caaagccatg ttctaatagg aattctgcct tttggaaatc ctcaggcaag ctttcacgaa
     2341 ccgtattttc aatcacacga cgcccagcaa aaccaaccaa gctctgtggt tcagccagaa
     2401 tgatatcgcc ttccatagcg aaagaagctg tcacaccacc agtcgttgga tctgtcaaaa
     2461 tggtcaggta aaagagacca gcatttgaat gacgtttaac cgccgcagag atcttagcca
     2521 tctgcatgag actcatgatt ccttcctgca tacgggctcc accagaggct gtgaatagga
     2581 caactggcaa tttttcgaca gtcgcatact caaacaaacg agtgattttt tcacctacaa
     2641 ccgtacccat agaagccatg ataaagttag aatccataat cccgagagcc acagtctgac
     2701 ctttaataag agcagttcct gtcacaacgg cttcatgcag acctgttttt tcacgcatag
     2761 atgccagttt cttttggtaa ccagggaaat gcaagggatc cttgctttca atccctgtaa
     2821 acaattcttt gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg gcagaaatac
     2881 gaaaggtata gctacagtgc ggacagatac gttcacttcc cagatccttc tgatagatgg
     2941 tatgcttaca gcctggacac tgggaaaata attcatctgg aacctctggc ttagcttgag
     3001 gtttttccct aaccgaacga ttgggattga ttcgaatata cttatctttt ttactaaata
     3061 gagccattga ttcccctttt cggtttaaac tcttaaagtc attttattct ttttcttgat
     3121 atttaggtaa gaaggtttcc atcaagaagg aagtatcata atccccagca atgacattgc
     3181 gatctgaaat gaggtcaagc tggaaatctg cattggtctg cactccttca atctctaatt
     3241 catagagggc acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg tgtactatga
     3301 ttttggcaat catactatca taataaggcg gaatggtata acctggataa actgctgaat
     3361 ccacgcgcaa gccaactcca ccacttggca gatagagatt agtaatctta cctggacttg
     3421 gagcaaagtt aaaggctggg ttttctgcat tgatacgaca ctcgatggca tgaccgcgta
     3481 ggacaatatc ttcttgctta acagacaaag gctgacctgc cgcaatgcaa atctgttcct
     3541 taacgatatc aacacctgaa acaaactctg ttactggatg ttctacctga acacgagtat
     3601 tcatctccat gaaatagaaa ttgctacttg cttcatcaag aagaaattca atggttcctg
     3661 cattctcata gccaacaaac tctgccgctc gaacagcagc agcacctatt tcatgacgca
     3721 gcgtttttcc gattgcaatc gagggacttt cttccaaaac cttttggtta ttcctttgaa
     3781 gagaacaatc ccgctcaccc aagtgaatca catgtccatg ctcatcacct aggatttgaa
     3841 cctcaatgtg ccgagctgga tagataaccc gttctatgta catggcacca ttgccataat
     3901 tggccttggc ctcactagag gcagtttcaa aggcagaaac gaggtcatct ggtttttcaa
     3961 ccttacgaat ccctttacca cctccacctg ctgaagcctt gagcataaca ggatagccaa
     4021 ttttttcagc aacaatcaaa gcttcttcag agttatgcac ttctccatct gaacctggta
     4081 taacaggcac acctgcttta atcatctgag cacgcgcatt gatcttatcc cccatcatat
     4141 ccataacatg accagatgga ccgataaact tgatacctac ttcttcacac atggtcgcaa
     4201 atttggaatt ttcactgaga aatccaaaac cagggtgaat agcttctgcc tcagtcaaga
     4261 ctgcagctga tagaactgca ttaatattga gataagactc tgttgccttg ccaggaccaa
     4321 tacaaactgc ttcatctgcc aaaagcgtat gaagagcttc cttatcagca gttgaataaa
     4381 ccgctaccgt cgcaatcccc aattcacgtg ccgcacggat aatacgaacc gcaatttcac
     4441 cacgattggc aattaaaatt tttcgaaaca tggagaacct ccttagttcc caattgcaaa
     4501 agtaaggata ccactggctg caagcttgcc atccacttca gcctttgctt caaccacagc
     4561 tatggtgcca cgacgtttta caaaagtcgc tgtcataacc aattggtcgc ctggtacaac
     4621 ttgcttcttg aacttaacct tgtccatacc agcgtaaaag accagttttc ctttattttc
     4681 aggttttgat aactccaaca caccagcagt ttgcgccaag gcttccataa tcagaacacc
     4741 tggcataact gggtattgag gaaagtggcc gttaaagaaa ggttcgttaa tggtcacatt
     4801 tttgatagca acaatggtat cctcgctcac ttccaagaca cggtccacta gaagcatagg
     4861 ataacggtgg ggaagagctt ctttgatttc ttgaatatcg atcatttgat acgtaccaat
     4921 cctttaccaa actcaaccat ttcttcgtta gagacgagaa tttccgttac cacaccatcc
     4981 ttaggagctg ggatttcatt catgactttc atggcttcga taattaccaa tgtttgacct
     5041 tttttgacac tatcaccaac tgtaacgaag gcaggtttat ctggtccagc agccaagtaa
     5101 accactccaa caagtggact ctctacaaga tttccctcag tagccacact tgcttcagct
     5161 ggagctggaa cttcttctgc tacagtctct gctggagcag atgtaggagc tactggactc
     5221 ggtgttgcta gaacgggtgc tggagcgact tgagttgcaa cttcaggcac aggtctcgct
     5281 tcattcttgc taaactgcaa ctcatccgtc ccatttttat aagaaaattc tctcaaactt
     5341 gactggtcaa attgagtcat caagtcttta atatcgttta aattcatact tatctattct
     5401 cccaacgttt gaaagcaaga actgcattgt ggcctccaaa accaaaagta tttgaaatag
     5461 cgtatggaat ttctttctcc aagccttgtc cataaacgac attagcttcg atataatctg
     5521 atacttcact tgtcccagct gtcattggta caaagttatg gcgcatagct tcgatggtga
     5581 cgatagcttc tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac ttggttgatg
     5641 atacaggtac ttccttacca agaacagcta cgatagctcc actttctcct ttttcattgg
     5701 caggagttga cgttccgtga gcattgacat aggctacttg ctctggagaa atctcagctt
     5761 cttccaaggc tagtttgatg gccttgatag ctccctgacc ttctggatgt ggagaagtca
     5821 tgtggtaggc atcacaagta tttccgtaac caaccacttc agccaggata gtagctccac
     5881 gtttttcagc gtgttcaaga ctttctaaaa ccaacatccc tgaaccttca cccataacaa
     5941 acccattgcg atccttatca aatgggatcg aagcacgagt tggatcctct gtagtagaga
     6001 gagctgttaa ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct tctgttcctc
     6061 ccaccaacat cacatcttgg aaaccaaact taatggagcg gaaggcatcc ccaatcgcat
     6121 catttgatga agagcaggca gtattgatag atttacaaac accgtttgca ccaaaacgca
     6181 tggctacatt cccagaagcc atatttggta aagcttttgg aagagtcatt ggtttgacac
     6241 gtttgggtcc tttttcatga aggcgaagta cctgatcttc aatttccttg attccaccaa
     6301 taccagatgc aacgataaca ccaaaacgat ccctattaag agcctctaca tcaagattgg
     6361 catgatttac agcctcttgg gctgcataca aggcatataa agaatagtta tcaaaacggt
     6421 tggtatcttt ttttacaaag tatttatcga acggaaaatc ttggatttct gccgcattat
     6481 gcacatcaaa gtcactatga tcaaattttg taatgccacc aatgccgatt ttcccagttg
     6541 ctaaactatt ccaaaattct tctggtgtat ttccgattgg agatgttact ccataacctg
     6601 ttaccactac tcgatttagt ttcattcttt tcacctctag ctttcgctac atacttaagc
     6661 caccatcaat ggcaatcact tgaccagtta gataatcttg gcctgctaaa aatactgtca
     6721 aatctgcaac ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct agtgtagctt
     6781 ccttaatctt atctgataag atagctgtca tatcagactc aatcattcct ggagcaatca
     6841 cattgactcg tatattccga ctagcgacct cgcgtgccac agacttggta aagccaatca
     6901 agccagcctt agaagcagca tagttagctt gaccaatatt ccccatcaaa ccaacaacac
     6961 tagacatatt aatgatagca ccttctctgg ctttcatcat cggtttcaag actgattgtg
     7021 tcatattaaa ggcaccagtc agattgacct tgagcacttt ttcaaaatct gcttctgtca
     7081 tcttgagcat aagagtatct tgggtaatcc ctgcattgtt gaccaaaaca tctactgaac
     7141 ccagttctgc aatagcttga tcaatcatac gcttagcgtc tgcaaaatct gatacatctc
     7201 ctgaaatggg aaccaccttg ataccatagt ttgaaaactc agcgagcaat tcttctgaga
     7261 ttgccccacg actgtttaag acaatgttgg ctcctgcttg agcaaacttg tgggcgatgg
     7321 caagaccaat tccacgactc gaacctgtaa taaagatatt tttatgttct agtttcattt
     7381 ttttcctttc aaaacttcta cttattttag tctatttttc taaaagtgct actaaactcg
     7441 cttgatcttc cacatgagct aagtgagcag tttgatcaat ttttttaaca aaacctgaca
     7501 agactttccc cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc atgaccccaa
     7561 tactttcata gaaacgaacg ggttccttga cctgacgcgt caagagctga gcaatgtcct
     7621 ctttttgcat cacagcagct tctgtattgc cgactagggg acaagtaaaa tctgaaaaac
     7681 ttacctgagc tagagtttca gctagtttct ggctagctgg ctcaaggaga gcggtgtgaa
     7741 agggacctga caccttaaga ggaatcaagc gtttggcacc tgcttcttgc aaaagttcaa
     7801 ccgctcgatc aactgcaacc acttctccag caatgacgat ttgtgcaggt gtgttatagt
     7861 tggctggagt aaccactcca agttcagaag ctttttgaca ggcttcttca atgacctcta
     7921 ctggcgtatt gagaactgct accatcttgc cagagtcagc aggagccgct tcttccatat
     7981 aggctccacg cttagctacc aaggcaaccg catcttcaaa atccaaggcg ccgcttgcca
     8041 ccaaggcaga gtattctcca agagacaaac cagcaaccat atcaggctga tagccctttt
     8101 cttgcaataa acggtagata gcaaccgaag tcgctagaat ggctggttgc gtatagcggg
     8161 tctgattgag tttgtcttct tccgtatcga tgagataacg caaatcataa cctagcacct
     8221 gactcgctcg atcaatcgtt tctttaacaa tcggatactg atcatagaaa tcccgtccca
     8281 tccctagata ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc atttcttaca
     8341 actcctgtcc agcgagaggc ttcttcttga attttcttag cggctccgta atacaaatct
     8401 tttaggattt cttcagctgt ttcttcttta gaaacaagcc ctgcgatttg acctgccatg
     8461 acagagccac cctccacatc accgtgaaca actgctttgg ctagggcacc ggctcccatt
     8521 tgttcaaaga tttctaaatc aggatcttcc tgcttaaagg catctttttc agccagttca
     8581 aaatctctag tcaactgatt tttaatagca cgaacagcat gaccaaagtg ctgagctgaa
     8641 atcgtagtgt caatatccct tgcttttaaa attttctcct tgtagtttgg atgggcattc
     8701 gactcttttg caactacaaa ccgtgtcccc acctgtacag cctctgcacc tagcataaag
     8761 ccagccgcag caccttcacc atccgcaatt cctcctgcag caataacagg aatagataca
     8821 gctgtggcta cctgtcgcac caaggtcatg gttgttaatt taccgatatg ccccccagct
     8881 tccattcctt ctgcaataac agcgtctgca ccgatttttt ccatgcgttt agctaaagcg
     8941 acactaggaa cgacaggaat aacgattatc ccagcttcat ggaaacgttc catatacttg
     9001 cttggatttc ctgctcctgt tgtgacaact ttaacacctt cttcaataac gagatccacg
     9061 atatcttcca caaagggaga taagagcatg atgttgaccc caaagggttt atcagtcaat
     9121 gatttgattt tatcaatatt ggccttgaca acttctttcg gggcatttcc cccaccgata
     9181 attcctaatc ctccagcctt ggaaacagcc cctgccaaat caccatcagc aacccaggcc
     9241 atccctcctt ggaaaatagg atagtcaatc ttcaataatt ctgtaatacg cgttttcata
     9301 gtgcctccaa ccttccttgc ttacgtaata gttcgatttc accataattt gacagtcaaa
     9361 ctattaccta aacaagaggg agtgggtttc tccctactcc ttctactaat attctgctta
     9421 ttttgcttgc tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt cattttctgc
     9481 ttcgatttgg atatcaaaag catcttcgat ttctgagatt acttggaaca agtccaatga
     9541 atctgcgtcc aaatcatcaa aagttgattc aagtgttact tctgatgcgt cttttccaag
     9601 ttcttcaacg ataatttctt gtactttttc aaatactgcc atgataggac tcctttaaaa
     9661 taaatagttt ttttataaca atgtgttcac cacatgatta cctaaattgt aagaatgagc
     9721 gtgccccagg tcaagcctcc accgaagcct gatagaagaa cagtctggct accatctaaa
     9781 gggatgagac cttgttctac acactctgaa agtaaaatcg ggatactggc tgcactggta
     9841 ttgccatatt ccatcatatt ggctggaagt ttggctcggt caacaccaat ttttctagcc
     9901 atcttatcca aaatacggtc attggcttga tgaagtagca gataatccaa gtctgtcacc
     9961 tctataggag attcatcaat agtctgcttg atagacttgg ctacatctcg aatggcaaaa
    10021 tcaaagactg tgcgtccatc catcttcaaa aatgaatctg cactttcttg atctgaaaat
    10081 ggagaatgca aacctgaatg cccataagtt aaacactcgc tgcgacttcc atcgctattg
    10141 agactctcag ctaagaaatg ctcttgctcg ctagcttcta acaagacacc accagcacca
    10201 tctccaaaca acacagctgt tgatcgatcc gaccaatcga ctgccttaga gagggtttca
    10261 ctaccaatca ccaagccttt ttgaaagcga ccagaagcga taaacttttc agcagttgaa
    10321 agagcaaata caaatccact gcaagccgcg gttaagtcaa aagcaaaggc tttattagca
    10381 ccaatattag cttgaacacg agcagctgta gagggcatca tcgaatctgg agtaatggta
    10441 gctaggatga taaaatccag ttcttctcct gttattccag cttttgccat cagtttctta
    10501 gcaacctctg tagccaaatc actggtagat tctgttcttg aaatatgcct ttgtcgtatt
    10561 cccgttcgac ttgaaatcca ctcatcattg gtatccataa tctgagccaa gtcgtgattt
    10621 gtaaccactt gctctggcac ataatgagca acctgactta tttttgcaaa agccattatt
    10681 tcaaatcctc caaaaattgg taaagattag tcaagccttt acccatgaca gcaatttctt
    10741 cctcgctcat gccatcaata attttttcta ccatggcctt gtggaagcgt ttatgcagtc
    10801 tatgaatcaa gcgacccttc tttgtcaaat gcagatgcac cacacgacga tcctgttctg
    10861 accgaactcg ctcaatgtag cccttacgct ctaaattgtt caaacttgtc gtaacagttc
    10921 caagagttac catcaactct tttgacactt gacttggagt cacatctgga gccttaccga
    10981 tgacatcaat cgtatgcatt tctttgatgg agatatcctt aaaacgacta cctctcaagt
    11041 tcacttcctc aattacaagg acattgttaa atatagatgt taaatattca ttgattcgtt
    11101 ggtagtccat ttttcatatc cctccttctt caaaaaactt ttacaatcaa aacatttgac
    11161 agaaagaatt atatcaaaat tcaaagaatg atgcaagtat tttttatttt cctgtaaatt
    11221 taggtcttct tctctccgaa tgagctcgca ctccttcttt gaaatcctct gtttgagcta
    11281 aggatttctg taggttcagt tctaaagtag cgtaaccctg ccagtcttta aattggctct
    11341 cccaaaccaa cttcttaatg gcagcatagg aattacttga agcacgtctt aattttttaa
    11401 gaagctgttc tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa accaaccccc
    11461 attctagggc tttttctgcc gttaaagcct ctcctgtcat agctaattga gcagcacgcg
    11521 tcacaccgat actgcggctc aagagatgaa ttccccctgc atctggagcc aaaccaacac
    11581 caacaaaggc ttggataaac ttagccttat ccgtcgccaa acagaaatct gccgcaacag
    11641 ccatattcgc tgcggcacct gcaacagcac cgtcaacttc cattaaaaca ggtttggcta
    11701 tttgcttgat tttataagaa atcgtattga ccaactctgc gatttttgtc aatgatggaa
    11761 tatcatcctc atccactgcc cgcttcatct ctaccaaatc tcccccaact gagaagacct
    11821 tcccattggc attgattaag ataaaatgca cagctggatt ttcttctgcc aaagtcagag
    11881 cttctaaaat ctcctcacac atgggaatat gaaaaccatt tgcgacctca ggacggttca
    11941 aggtaaggat tgccaagtcc tcttcaagct gataaataat gtgttccatc agggctcctt
    12001 tttattttat aagcagttta tactcttcga aaatctcttc aaaccgcgtc agcttccatc
    12061 tgcaacctca aaacagtatt ttgagctgac ttcgtcagtc ttatttacaa cctcaaagca
    12121 gtgctttgag cagtctgcgg ctagcttcct agtttgctct ttgatttcat tgagtgttaa
    12181 attatttcac tgtcaaagta tatctttttt aggagcagaa agcaagaaaa aatcgactga
    12241 aagtgtctca gccgataaga aaggctcgct ttaggctaga aagcatctta ttttcttcat
    12301 tgaaaaaagc ctttctttct gctataatcg tataaaatac ttactttagg agttcttatg
    12361 aaagttgtta aatttggagg tagttctctt gcctctgcta gtcaattaga aaaagtttta
    12421 aacatcgtca aaagcgattc agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc
    12481 aatgctgaag atactaaggt tacggatgcc ctgattaaat actaccgcga ctatgttgcg
    12541 ggtaacgata ttagcaagag ccaaagctgg attatcgacc gctatgctgc tatggttagt
    12601 gaattgggac taaaaccagc tgtgctagaa aaaatttcta aaagtattca cgccttggcc
    12661 actcttccta ttgaagaaaa tgaatttctc tacgatactt tcctagcagc cggtgaaaat
    12721 aacaatgcca aattgattgc tgcctacttt aaccaaaatg gtatcgatgc acgctatatg
    12781 caccctagag aagctgggat tgtggtcaca agtgaacctg gtcacgctcg catcattcca
    12841 tcaagttatg acaagattga agaattgaca aacaccaatg aagtccttgt cattcctggt
    12901 ttctttggtg tcactaagga aaatcaaatc tgtactttct cacgtggagg ttctgatatt
    12961 acaggttcta tcattgctgc tggtgtcaaa gctgacctct atgaaaactt tacggacgtt
    13021 gatggtatct ttgcagccca ccctggtatt atccaccaac cacactcgat tcctgagttg
    13081 acctaccgtg aaatgcgcga gttggcctat gcaggcttct cagtccttca tgacgaggct
    13141 cttcttcctg cctaccgtgg aaaaattcct ctggttatca agaataccaa caaccctgac
    13201 catccaggta ctcgtatcgt tctaaaacac agtaatgatg aatttccagt tgtgggaatt
    13261 gctggtgact caggctttgt cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt
    13321 ggatttggcc gcaaggttct gcaaatcctg gaagaactta acatcggttg ggaacatatg
    13381 ccaacaggta tcgacgatct ttctatcatt ctccgttctc gccaactaac tcccatcaag
    13441 gaagaagaaa tcctgcgtca gttggttcaa aaggctaaag tagatcatgc agaaatcgaa
    13501 cacgaccttt ctatcattat gattgttggt gaaaaaatga agagccacat cggagtgact
    13561 gctactgcga cacgcgctct atctgaaaac aaaatcaaca tccagatgat gtctcaaggt
    13621 tctagtgaag tttctattat gtttgttgtc aataaagacc aagagaaagc agcaattaaa
    13681 gccctctaca atgccttttt tggagaaagt aaggaagact aagcatggcc caatcactta
    13741 acaaaacagt actcctcagt acgacaggca cttcctacct ctctatcgct gggaaagttg
    13801 ggaaattcct tgtcggagat caggctttgg aattttaccc agatgtcaat gtcgaacaat
    13861 ttatccagat tccttggagc catatcaatc agattggagc caatgtcact ggacgcaaaa
    13921 tcagccgcca cttcgaagtc tttacagaca aaggaaaatt cctctttgct tcaaaagact
    13981 caggtgccat tctcaaaatt gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc
    14041 cgaccctgat tcagacaatt agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac
    14101 tttagtataa tcatagcaac ggataagtag gttatcttct tctttcagaa agtctgcggg
    14161 tactgcgagc agataggagg gataggtgaa attctaccgt tagtaacaat tacatacaca
    14221 atcaagtgca cacctgtgaa gttggatgga accgtggccc tgccactcca acgttttgtc
    14281 aggcgtgctt ttttcataaa ggagttctta tgttagatat caaacgtatt cgtacagatt
    14341 ttgaagctgt cgcagaaaaa ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa
    14401 tgaaagaaat cgatgctaaa cgtcgtaaca tcttgattaa ggttgaaact ctcaaagcag
    14461 aacgtaacac agtttctgct gagattgccc aagctaagcg caacaaggaa aatacagatg
    14521 acaagattgc tgccatgcaa aatctatctg ctgaggttaa agccttggat gctgaattgg
    14581 cagaaatcga tgctaaattg acagaattta caacgactct tccaaatatc ccagctgaca
    14641 gcgttcctgt tggggctgac gaagacgaca atgtggaagt tcgccgttgg ggtactccac
    14701 gcgagtttga cttcgaacct aaagctcact gggatctcgg tgaagacctt ggtatccttg
    14761 actgggaacg cggtggtaag gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg
    14821 ctcgtttgga acgtgctatc tacaacttta tgttggatga acatggaaaa gaaggctata
    14881 ctgaagtcat cacaccttac atagtcaacc atgattctat gtttggtact ggtcagtatc
    14941 caaaatttaa ggaagatact tttgaactca gcgataccaa ctttgtcttg attccaactg
    15001 ctgaagttcc tctgacaaac tactaccgtg atgaaatctt agacggcaaa gatcttccaa
    15061 tctacttcac tgccatgagt ccgtcattcc gttctgaggc tggttctgcc ggtcgtgata
    15121 cgcgtggctt gatccgtttg caccaattcc acaaggttga aatggtcaaa tttgccaaac
    15181 cagaagaatc ttacgaagaa ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa
    15241 aactcaacct tccataccgt gtcgttgctc tctctactgg agatatgggc ttctcagctg
    15301 cgaagactta cgacttggaa gtgtggattc cagcacaaaa caattaccgt gaaatctcaa
    15361 gctgttcaaa cacagaagat ttccaagccc gtcgtgccca aatccgttac cgtgatgaag
    15421 cagatggcaa ggtgaaactc cttcatacct tgaacggttc tggacttgca gttggacgta
    15481 cagtggctgc aattcttgaa aattaccaaa atgaagatgc ttctgtgacc atcccagaag
    15541 cacttcgtcc atacatgggt ggagctgaag tcatcaaacc ataaaaaata aggtttagct
    15601 atttctagct agaccttttt tcgtaaccaa atcagataag cacctagtac aaagaataaa
    15661 atagttaggc atataatggt ttcagccaat accaggtaat ccagaaatgg aagtttcaaa
    15721 attccctgag ccatcttgag cgaggtcgct gtgataatgg ttgggaaggt gagggctgag
    15781 aaggctggtt gaaaaccttg ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag
    15841 aaggattgag aagccaaaat catgacaatc aagacccaag tcggcaggct ggttcctcct
    15901 actcgaacta gagaagccaa gagtagagag aaaggagcac agtagattcc ttcttgtcca
    15961 agcaaggcta gtgggagtgg atgtttcttt aaatcgctat aaataagggg atagagatag
    16021 aaggtcaaga gaaaaccaaa actcaaggtc gcataggcaa tttcgataat acctaccaga
    16081 ggataggtca aggcagccac tgctatcccc acatagagaa ccgtccaact tggagtggca
    16141 tgaaccctcc gccctggaca agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc
    16201 aagagaaatg aaaaccacca aatcccttgt gctaccaaag gaagataaga gaatacgcga
    16261 aagacatagg tcgataaaat catcccagcc ataggaaagg ttgccattcc tgacaaaaga
    16321 gggggcttgg tcaattcttg cttggtttct ttccaattaa agagatgcag aattagaaag
    16381 taaatccata aaaccaaacc agtcagacta aaaagatggg atagaaccgg caacgtatct
    16441 aaaataagat ttccagctcc tgccaaacct agcaaacaac ctgaaaatac taaggggagt
    16501 tttttcatcc taacctccaa taatcatgtt agtttcagta taacataaaa gcgcttaaat
    16561 gaggatttaa aaaaacgaag tccgcttatt tcagacttca ttttactcag atatgaatta
    16621 ggcataaggt tgcaattctg gattaattgg tgtattagct aagttgttgg catagttaca
    16681 gaggattgct aggctgacac caaaaaccac atccaaggca ttttgttgag tgtagccagc
    16741 ttctaaaaac tcagacaagg cttcatctcc tacacgaccc ttggtattga taactgccaa
    16801 ggtaaactta gctagggtat ccaatttagg atctgtttca attggagtac gattgcgaag
    16861 agcttgaatc aagtcatcat tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc
    16921 gacacagaag gcacaaccat tggtcacggc tgccgtgatt tgcaccactt cacgctcaac
    16981 gggtgtcagg ctgttgcgac ggtggataga tgagacaatt tgataggctt ctaaaacagt
    17041 cggggcattg gccaagagac cgattaggtt gggaatatag ccattgttgt ctttttctac
    17101 tgtttcaaga atttctttca cttctgctgg tgctgactct actgtatgga tagtaaatgt
    17161 tgtcataaga tacctctttt cttattattg acactaatat tattggaaaa tcttataaaa
    17221 tcctgattcc taagtttatc taagataaag ctttattctc tcataagatt ttcgttgtta
    17281 tattagttta tcacacttcc aatcacttgc ataatatata ttatatatca ggctgataaa
    17341 aattatttat aggcaaaaaa atcacacgag ctgtgtgatt ccattatttg tcaaaatact
    17401 ttttagtttc agcaataacg actggcgaca agaccaagag ggcaatcaag tttggcagag
    17461 ccatcaaggc gttaacgata tctgcgataa tccagaccat atccaactcg ataaatcctc
    17521 ctaacaagac catgagcaca aaaaccacac ggtagagcca gataaagcga accccaaaga
    17581 ggaactcaaa acagcgttct ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa
    17641 gtacaaggaa gatggtcaag agggcaggcc caaagtgtga aaagactgtt gagaaagctg
    17701 actgagtcaa ggcaacccca ttcaagtcac cactccaaac tccagttacc aagatggtca
    17761 aaccagttag agtacaaatg atgagggtat caataaaggt tcctgtcatg gaaatcaaac
    17821 cttgctctac tggttcattt gtcttggcag ctgcagctgc aataggagca gaacccagac
    17881 cagattcgtt tgagaacaca ccacgcgcca caccattttg aatagccatc cgaacgctag
    17941 caccagcaaa tccacctacc gcagcaaggg gactaaaagc tgaggtaaag actaaagcga
    18001 ttgtgccagg gatttttccg atattaaaga aaataactgt aagagttcct aagatataaa
    18061 tgatggccat aaaaggaaca acagtagttg aaaccttaga aatagacttg agtccaccaa
    18121 agactgcaat cgctacaaag acagacaaga cgagagctgt gatggctggc gaaatcgtcg
    18181 ttgtattttg gatagattct gcaatcgagt tgacttgggt gaaggttccg attcccaaga
    18241 gagcaaccaa tactcctgct actgcaaaca aaacagcaag tggtcgccac ttttctccca
    18301 tccctagaag gatataatgc atgggacctc ccgctactgc accatggtcg tccttggtgc
    18361 ggtatttgat ggccaagagt ccttccgcat acttggtagc cattccaaag aaagccgcca
    18421 tccacatcca aaatagagct cctggtccac caaccttgat agccgtcgca actcctatga
    18481 tatttcctgt tccaacagtt gatgccaagg ctgtacacag agctgcaaaa ctggatacat
    18541 caccatgtcc cttatcctgg ataaaaataa gctgaaaagc cttgggcaga cgcaaaacct
    18601 gcaagagtcc tagccgaata gttaggtaaa tccctgttcc gaccaataaa atcaagaggg
    18661 gcggtcccca agcaaaagca tcgattgatt taagcaattc taacatttcc ttctcctatc
    18721 gtttcaaccc caaaagaaag agcacatgca agatacatgt actctggaat gcttagataa
    18781 atgctaaaaa gcggtctatc ctagctctgt ccttttacct gagagtttga gcagttgcct
    18841 gccttgcccc ttcggtgcct ttacggtctc tccagagttc cgtccattta cagtcatgga
    18901 aaatcaaacg attccccact tctattaaac ttcattcggt gttggtattt aattgattct
    18961 aattttacaa aaaatgttgg cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag
    19021 tttttacttt ataaagtcca gaatactgct atcctttaaa agtgacaata gtcgcaccac
    19081 tgcctccagc attttgtggg gcatagccga aactcttgac atgtttgttt ctttgcaagt
    19141 atttggtaac tccttcacgg atgactcctg ttccgatacc atggatgata tcaacttgag
    19201 ccatattgtt aagcaaggct tggtcgatga aggtatctag ctcattcatg gcttcttcat
    19261 agcgcttgcc tcgaagatcc agtctagctt gaggtcctcg cccagaagtt cgtttcacaa
    19321 cattgacctg tttcttcttg actggttttt cttgctgggc ttgaacaaga tcaaactctt
    19381 tctcttccaa ggtcatctta atcaagccaa cttgggcttc ccagcggccg tccttgagtt
    19441 gactggtcaa ggtaccacgc tgaccataac tgagaaccac gatatcatct cccacctttg
    19501 gagctcgttt tttcttggcc ttttgaagga ccttgttttt agacaagtcc actttttcag
    19561 gagccaattt tttcaacttg gccttggctt caatgatttc gtggggcttg agttgggatt
    19621 tactgtggag atttttgaga atctggtcac tttcacttag ggccatatcc acaatctcag
    19681 cagcctgttc acgcgccttg ttaagctcgg tttccttttc acgattaagc tcgttgtaga
    19741 gtttttttag cgcacggttc atcttgagat tttcttgctc cacctcacgg atattgtcca
    19801 agcgtttgcg gctttccagc gtctgctctt ctaattgctc aatgatacga ttgacgtcat
    19861 tgtcctgatc gatctgctga ctggcatctc ctacgataac ttcagatagg cctagacgtt
    19921 tggcaatttc aaaggcatta cttcggccag gaacaccctg cataaagcga taggtcgggc
    19981 gaagagttgc agtatcaaac tccatactgg cattttgcac aaaggctgtc tcaataccgt
    20041 aggccttgag ttctggatag tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt
    20101 cctccagaat agccatggca agggctgctc cctcttgggg atcagtacca gcccccaact
    20161 catccaaaag taagagtgaa tgttggttga ccttgccaag aatatccacg atattggtca
    20221 tatggctaga gaaggtagac aagctctgct caatagactg ctcatctcca atatcagcaa
    20281 aaatttcttc aaaaatacca acacgacttc ccttgtctgc taaaatcggc aatcctgact
    20341 gggccatgac ctgtgtcaag cccagagttt tgagcatgat ggtcttccca cctgtattgg
    20401 gacctgtaat gacaatagct gttaaatctt gaccaaaata gacatcattt gcgacggcat
    20461 ttttgaccaa aggatggcag acatggagca gttgaatctc ttgattttct gacagctgag
    20521 gcacgactgc ttgtctttct tggataaatc gaaccttggc acgaatcaag tccagatgac
    20581 cgataatcca agcatcatta gcaatctcag ccgcatgagg gcggacacgc tcagaaattt
    20641 cttggagaat gcgaagcatt tcatagcgct catctgctcg cagactagca atttcttcgc
    20701 tcagtttgac tacctcacgg ggttcgatat agacggtgtt tccactagca gaaatatcat
    20761 gaacgacacc tgcaatctta ttgcggtagg tgtttttgac tggtaaaacc ttacggccat
    20821 ttctgctagc aacaattcct tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta
    20881 aaacatcgcg tacctgactc tcgctatcat gtatttttcg acggattcgc gccaattctt
    20941 cactggcaaa attttcaatg aaacccgcat cattaaaggc ctgaagattt ccttgtaatt
    21001 gcggaaaatc atgtaatttc tcaaaccaaa gggctaattc ttccaagctg acattttcca
    21061 gattggcgta aaaactttga agttctcggc tggcaagaag cacgcgtttc aagagtagga
    21121 actcctcgat attgagatcc gctcccatct ccaacctctt gcagactcct gcaatttcct
    21181 tagttgagag aatagtaaaa tgcggttgct cgacgaaaag agcctgcatt tccttcatct
    21241 cagcaaaagc ctgtttgatt ttatctgctt tggcagtcgg agccagttgt ctcaattgct
    21301 ccaagccctg ctcggtcaac aaatgaggct caaacaaggc cttgacctta tcgaactcta
    21361 atgtttctaa tattttctta ttcatcttta tttccttgtc tttgaatgtc taggtgtggt
    21421 aactttttac attctgatag attcaagtca aatctgtaaa caaagggcta ggaaaactcc
    21481 tgcccttttt atccgattaa atttgtcacc cagatttgtt tgagccaact ggttgttatc
    21541 ggtatgctct ggatgatgtg ttttgcgacg atactctttt caagaggatt ttgtataact
    21601 gccatgggga tggtcgccaa gattgtcaag gccatttgca agacaaataa ggtcaccaac
    21661 atggacaaga tacctgctga aacttggaac aacttaccac ccagtttttt gctaggaatc
    21721 aagtgtaaga gaagaccaag caaacgacca atgctataga caatcccaaa tacaagcaag
    21781 tagccgatac ctgcataaaa gaccttatcc agctgaaaga gttgatccga tgggaaaaag
    21841 aaagtcccct gaccttcctg cgaatttgca taagggagca ataaatggaa ttgctctcca
    21901 agccccttat aaaactggcc agccataaaa gccgatgcca tggctgaaat caggtaataa
    21961 atctgtaaga gcaggcctct ccgatagccg atataaaatc cccaaaccaa gaccaataga
    22021 agaaggaatg aaatcataag gaatcctcaa tcttgctctg ttcttgctta caagtcacaa
    22081 gcttgtgacg gagttcttct agctcttgct ccttatcgtc aaattcaatc tcacggctga
    22141 gctgagttga taaacagttg actgccaaca aaagagcgat tgtttcatca tctgcgctag
    22201 gcatttgttc tttaattgct tggtattttt ctgtcgcaac cttagcgatt tcctccataa
    22261 aaaggttatc atgttcactt gtcaaggtta acgatttttt cccgaatgta aatttgaatc
    22321 gatttagatt tgccataaaa ttcacctcac gatattatac caaaattcgc taattttgtc
    22381 agtttttaca aattttactg cttttgtggt acaatagaaa ctatggcaag tatcacactc
    22441 acaccaagcg aaaaggatat tcaggctttt cttgaacact atcaaaccag tctggctcct
    22501 agcaagaatc cctatatccg ctactttttg aaactacctc aagcaacggt ttctatctat
    22561 acttctggaa aaatcttgct tcagggtgaa ggggctgaaa aatacgccag tttctttggc
    22621 tatcaagctg tagagcaaac cagcggacaa aatcttcctt tgattgggac agatgaggta
    22681 gggaatggtt cctactttgg tgggcttgca gttgtggctt cctttgtcac acctgaccag
    22741 catgccttct tacgaaaact cggtgtggga gattctaaga ctctgaccga ccaaaagatt
    22801 cgtcagattg ctcctattct caaggaaaaa attcagcacc aggcactcct tctctcaccc
    22861 agcaagtaca acgaggtcat cggagaccgc tacaatgctg tttcggttaa ggttgccctc
    22921 cataatcagg ctatctatct cctccttcaa aaaggtgttc agcctgagaa aattgtgatt
    22981 gatgccttta ccagtgctaa aaattatgac aagtacttgg cacaagagac caatcgtttc
    23041 agcaatccta tcagcaatcc tatcagctta gaagaaaagg ctgagggcaa atacttggct
    23101 gtcgcagttt cttctgtcat tgcgcgtgat ctctttctgg aaaatcttga aaatttggga
    23161 cgagaactgg gttatcagct tccaagtgga gctggaacgg cttctgacaa ggtggctagc
    23221 cagattttgc aagcctatgg tatgcaggga ctcaacttct gcgccaaatt gcactttaaa
    23281 aatactgaaa aagcgaaaaa cgcttagaaa ggtaagttat gaatttattt aaaaatttct
    23341 taaaagagtg gggattattc ctcctgattc tgtcattact agctttgagc cgtatctttt
    23401 tttggagcaa tgttcgcgta gaaggacatt ccatggatcc gaccctagcg gatggtgaaa
    23461 tcctctttgt tgttaagcac ctccctattg accgttttga tatcgtggtg gcccatgagg
    23521 aagatggcaa taaggacatt gtcaaacgtg tcatcggaat gcctggcgat accatccgtt
    23581 acgaaaatga taaactttac atcaatgaca aagaaacgga cgagccttat ctagcagact
    23641 atatcaaacg cttcaaggat gacaaactcc aaagcactta ctcaggcaag ggctttgaag
    23701 gaaataaagg aactttcttt agaagtatcg ctcaaaaagc ccaagccttc acagttgatg
    23761 tcaactacaa caccaacttt agctttactg ttccagaagg agaatacctt ctcctcggag
    23821 atgaccgctt ggtttcgagc gacagccgcc acgtaggtac cttcaaagca aaagatatca
    23881 caggggaagc taaattccgc ttctggccaa tcacccgtat cggaacattt taagagacct
    23941 aagaggccga gaatcaccaa tctcagcctc ttcttctatc gtgagaaaat gattggtaac
    24001 tatctaaact taccagaaca gaaacacctc aactctcacc tattcatgca aaggaatttt
    24061 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    24121 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    24181 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    24241 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    24301 aaaccaacta gtaagggctt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    24361 ctcaagacag ctcagaaaat cgtggatacc tatggcgaaa ataccattga cgaaattttg
    24421 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    24481 gtctccactc tccgtctcaa ctacggaacg gagatggttt tggccaaact agccaactac
    24541 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    24601 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttaccatt
    24661 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    24721 ggtctagttc acagtctttt tcaggcctgt atggaaacag gggacaccta tgttgaagca
    24781 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt ggaactagac
    24841 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    24901 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggcatccg cagtcacttg
    24961 gttcgtatcc ttgaaaaagg aaaacagaag agtcatgatt taaaaaccat tcaaaaacat
    25021 atcactacta tcgagaaaga gcttggaatt gagtatgata acattcaaaa acaggctatc
    25081 tgtgatgcta tccagaataa ggtctttatc ctgacaggtg gacctggtac tggtaagaca
    25141 actgttatca atgggatcat cgctgtttac gccctgttag agggacttga cctcaggaag
    25201 aaaagcaacc tgcccattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    25261 gaattgacag gtttgcctag cgcgaccata caccgccact tgggaatgac aggtgacgat
    25321 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    25381 atggtggata cttggctggc caatcaactc ttctccagta tctcttctaa cagtaagatc
    25441 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    25501 ctgcttcata ttcctttgat tcctcagact cgcttggaaa aaatttatcg acaaagcgaa
    25561 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    25621 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    25681 attgaaaaaa tcttaggtgc cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    25741 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    25801 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    25861 aagggagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    25921 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    25981 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    26041 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    26101 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    26161 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    26221 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    26281 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    26341 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    26401 gacctcaaag agatttttgg aaaatagtac atcagaaaac ccaccaattc aggtgggttt
    26461 tctgtttatt aagattattt tactgttgct gtgcttgtga tcaattcaac agcttttttg
    26521 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    26581 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    26641 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    26701 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtgatttg gaagtacatg
    26761 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    26821 tcttcatgga tcatttcttc tggaagttct acgatttcag cgttttctac agctgtatca
    26881 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    26941 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    27001 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    27061 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    27121 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    27181 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    27241 gaaccaacga agtcgatcac aacagtgtcg ccgttttcag cagcagcttc cttgataacc
    27301 aattcagcca ggttgttgcg ttcgcgttcg atacgctctt caacatcagc gtcagttact
    27361 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    27421 tttgtaacga cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    27481 atttttggtt gggcaaccac ttcaagacca gcttctttta cagctgcttc ataagcgttt
    27541 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttatcgaag
    27601 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    27661 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    27721 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    27781 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagccaat
    27841 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    27901 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttcagttat
    27961 atagtagatt gaaactagaa tagtacacct ctacttctaa aacattttta gaaatcgctt
    28021 tgactgtcct gatcgatttg tcctgttctt gtttcatttt actatataga tcgcattcga
    28081 aagaattcgt tccaaaattg cttggttcgt tcttctcttg gacgactaaa gaattgatgg
    28141 gcattatttt tttcaacaat tttcccaccg tccataaaaa taacatgatg ggctacatct
    28201 ctagcaaaac ctatctcata aagctgatca aaaactcaat ctgaggagaa aatccaataa
    28261 ggctttccat aataaaggac atcctatcaa gatttttgaa cacccgatag gctgcctttt
    28321 tccgattttg aagacttttt gtccagcttc ttttacctta taaataacaa caaaaatcaa
    28381 agacaagcta gaaagattac cgcagataac tcaaacagtg ttttgaggtt gcagataaga
    28441 ctgacggagt cagctcaaag cactgctttg aggttgcaga taagactgac ggagtcagct
    28501 caaagcactg ctttgaggtt gtagatagaa ctgacgaagt cagtaacata tgcctaagac
    28561 aaagcgatgc taacctgatt tgaagagatt ttcgaaaaat attaaatata ctctacaatt
    28621 tgctcaatca attcttggtc gtctaaacct gtaacttgta taacaacatc tttgactgat
    28681 tgtttagcca acaattcacc taatcgaata ctttcttcat catttacatc gcgatagtca
    28741 aaggcatagc caactgtttt aagtaggttt ttatatgaca aactgagttc tttcaattca
    28801 cgtatcggcc ggatgaatcg ttcattatag cctaattttc ggattggagt acgagctacg
    28861 cgactaacct cgtccactat gaaagggttt tcaaaccgtt ctataatgac tttgtgataa
    28921 ttctccaatt cttttttatc aaagttccat ttggcaatca agagactccg aatttcagct
    28981 aatacagatt caatccgaga tttaatatta ggattttgaa gagcttccaa aattgtcttg
    29041 gcaccataat gcgcaccaat gtaagctgaa gttgcatgtc cagaattgac tgaaaaaagt
    29101 tttcgctcaa taaagggttc taaatcttct tcataatgca catcttttag acgtaaatct
    29161 ggatttttaa gacgcttggt ttccacgacc cattcattaa agggctcgac cacaacaaaa
    29221 agggaatctt cgtgactttg tgctggaaca atcctgtcta ctgcagcatt tggaaaacct
    29281 atgtagttat cagcaaatgt caaaccttcc ggacttaaat atttcttgac ttcttgataa
    29341 agaaattgag acccgccaat catattttca caggccataa catccaatac ctgtgtattc
    29401 cctgcaactc ggcgagcttc gattcctttg gctagaagtt cagcgataaa agggagtata
    29461 ttaggtccga ttgcagtagt aataatatcc gtcttttgaa tcgcttcaat gacttgctca
    29521 ggatgttctt tgctattaat tccagccaca ttagttactt ctatacgaga ctgtcctttc
    29581 tgtgcaattt caatttcata cttgcccttt tcatttagag catgaattat ctgattattg
    29641 acatccacaa aatcaatatg gaaaccattt ttaaatagaa tttcacctat aaaaccacga
    29701 ccgatattac cggcaccaaa atgaacagaa tgtttcattc aatttctcct tttcctattt
    29761 gagggacata tatactagat ggcaaatgac gaaattcaat tattcaacag catcaaataa
    29821 gcgcaatact tcctcttttg actgagcatc ggctaattta agaacattat ctacatctgc
    29881 acagaagata gaaattttct gaataatttc taagtgttca ttaccaatac cagcaatacc
    29941 aaaaagaacc gttgccactt gagggttaga tacattccca aaatcaaccc ctctagggac
    30001 ttgaacgact gtaataccag acttgaggac atcctttttt gctgcatctg ttccatgcgg
    30061 tattgcgata aagttaccca tgtaaacaga tagctcttta tctcgctcaa tcatggcttc
    30121 aatatagtct tcattaacat atccaccctc ataaagaact tgcccacaat aacaaatagc
    30181 ttcctccttg ttagaaaatt gtttattaag cttaatcaaa tgtttttcaa gtttcatatt
    30241 agttctccaa tttcttaatt ttttcgttaa aaatagtatt tagcatctga taaataatgg
    30301 attgatttcc cgtcttgtaa atctctgtat aaagatgatt ttcaataatc gactgactaa
    30361 tagctgtcat taaatctctc gcttcctcgc tagcttcttt agacattagc attagcagac
    30421 accttttgac ctcttcttcc tctcgtttca ttgacaatgc ggagataggt agtttgagtt
    30481 caaacatagt aaaactattt gttgttactt tgctagactg actatgtaaa agcaccagac
    30541 cagtattagg aatagccata ggactattct ggaagtgaga taacaatttt cttgttaggt
    30601 aatctctgtc actcacattc ttctgatatt ggatgatttg ttctaccgtg tgctcaaatg
    30661 attgattatt ctccaattga accaactcga attgactcaa aagctgacta ctagatatta
    30721 aataatcttg caagtcataa cttttctctg gagcgatagc atcacgcgcg acaattgtac
    30781 gatgtgcctg tacatactga agtcgttcct gtaattcaag caattctttg acggttggaa
    30841 aactagaaat tacatcgatt tcctgattag tcagcggctt ggtagataaa atataatcat
    30901 actgactgag atcaatactg tggtaatcta ctagagactg aatatctatc aactctacaa
    30961 aaggagcaac actcttaatt ttactgacta ataaatctct agtgacccga cgttcatccg
    31021 ttaaaagcaa aacacggact ggataaatct ctggactacg gcctaagcta gagataaaat
    31081 gtagggcaat catgccatac tcatactctg tatgaagata tttcggaaaa atatcattca
    31141 ctaaaagact gatgactgta taaagaaatt tattcctttc aactaaaatc tggacagatt
    31201 ctggcaaatt ttcaccctga aaaaggatag ggacgcctaa actgagccga atatgatgga
    31261 aaagaaaatt gaataaaacc ttgtccttaa aaaagtcaat cttggtatac atggaaaccg
    31321 tatcaatcag atttgaaata ttgtagaaaa attcaccatc aaatttctcc gtaaagagcg
    31381 gattgtcctg acgtttaatg attaattcat ccaagatgct cgcaaaatag ataatttcct
    31441 gaatactata aaattgtgca gtctgcttag agtaagcttg aaaaattttt tgagaaattt
    31501 ccaaagcctg cttactagta ttaggtgaat tttcaatgtt ttgctcctga cctataagag
    31561 ataacaagat cgcaaaaaac atcttcatcc tagcatccat atctggaaaa cctgacagtt
    31621 gcttattaac aatctgactg gccagcctag ttctatctgc ttctaaaata tcaaagctcc
    31681 caaaattacc ggttgaaaaa tctgctactg agatacagtt tgtcagtaaa atagccaaaa
    31741 atcttctctt accaactgaa tcaccagaaa tccgataacc tttttgtcgt tcaattttca
    31801 gatcaaagtc taaaagacgc ttatcaatat ctgaaatatc ctgaataata gttacattac
    31861 tgactttcgt gcactcttgc aatgcttcat tggtgacaaa accactctca gtcagaaggc
    31921 gataggtaat caactcttgt ctttcttggg gactatactc aactaacact tcaagttctg
    31981 tcggcaaatc atccaactct ccagtcaaaa tatagtattt cccatgcttc gttatttcga
    32041 ttccatattg ctccatgcta tctgtcaaat ctgataaagt tcgataaatt gttctagatg
    32101 aaacctgtaa gatttcagtc atatcttgca ttgaaagctt ccctacatgt aggaaagcct
    32161 tcaataattg ttcttctcgt ttggttaata gcattcgtaa tttagaaacc tctagttcta
    32221 tttgtacatt ctagcagcca ttttgtcata ttctggtgtt gttactaaac tatccacaat
    32281 aagaaattga gaattcggtg ctgcttgctg cacttctgcc tgtaaagaaa tagttgttac
    32341 aatcattatg tttttagaat taaattcacc taattctgaa attttggcag tagaaactgg
    32401 aatacgaata ttcttgtttc taaagatagc ccgaatcgtt tcacagccca tagttgcagt
    32461 tccctgtgct ttaccataag caactactac agcatcaata tggttaaggt caatttcctg
    32521 actatctact ggtgctgaag ttggtatatc tccttcaatt tctgctattg gaaaagctcc
    32581 tgttaatgaa gctacaattt catcataacg aggggacgct aagaaattat caacagaaac
    32641 atgaatagca cttggactct tgtctttagc tcttggtgtc agttcttcct gagtaacaat
    32701 taatgttttt ggtgtatcaa gcaaatttga gattgcctga ttagatactg gaatctctag
    32761 acctgctttt ttaaccttat ctcgaagaat actagctccc atagcagagc ttcccatacc
    32821 agcatcgcag gcgaaaatga ttttttccac tgagtctgtc gaaataactg catcaacaga
    32881 agttgatact aactgacctt tagactgagc tttagctgct tgggtagcct cttgagcagc
    32941 ttcgagcgaa tcctcagttg acttgtctgc atgaagaata agggctgcta caaagaaaga
    33001 aacaactgct gccactaaaa cacctagaag aacatttaga tggggccaaa caccttttgg
    33061 cgccgtagcc ataatcgcaa taatagaacc tggtgaagct ggagatttaa gaccagcgtc
    33121 taagagttga aaagtaaaag ttccagagat acctcctgcc atagcagcta aaaatagagt
    33181 aggcttcatc ataacataag gaaagtaaat ttcatgaatc cctccgaaga aatgaataac
    33241 cattgccccc caagaagaag atttagcaga acctttaccg aatacagcat aagctaatag
    33301 aattcccagg cctggtccag gattagcttc caataggaag agaattgact taccagcttg
    33361 agctacctgt tctactccca gaggagtaaa aatgccatga ttgagggcat tattgaggaa
    33421 aaggacttta gccggttcga tgataatatt agctatagga aggaggcgag cattgacaat
    33481 agcctcaaca ccattcccaa cagctccagt aagagtcgat acgactggac cgattgcgta
    33541 gaaagccaaa agcaataatg caaaaccaac gagaccagct gagaagttat taactaacat
    33601 ttcaaatccg ggacgaattt tttcctggaa cttctcatca aatttcttga tagtccatcc
    33661 tcccagtggg cccattacca tagctccgat aaacatagga acactagaac ctgtgattgc
    33721 accaacagta gcaatagctc ctacaacggc accacgttgg ccatggatca tatatccacc
    33781 tgtgtaacca atcaggattg gcaataaata cgttaacata ggaccaacaa cagtagctaa
    33841 ctgttcattt ggcagatagc catcagcgat aaagagggca gtcaatactc cccaagcaat
    33901 aaatgctcca atattgggca taaccatatt tgaaagcgat gtccctagtt tttgaaccct
    33961 gactttcaat gatacttttt cttccattag atcatcctcc ttttcttaaa actagtatat
    34021 acaaagttaa aaacctttaa aactaaagtt ttgtcacaaa ttttgtgtca aaacattact
    34081 tttgacgagg ctgggcaaaa aggcttaaaa atgataaaac gcatcatatc cggtgtac
//
LOCUS       DAVKUR010000020        32160 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKUR010000020 DAVKUR010000000
VERSION     DAVKUR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.020"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..999)
                     /locus_tag="VW749_001044"
     CDS             complement(<1..999)
                     /locus_tag="VW749_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0175092.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKKPEKFFG"
     gene            complement(1275..3380)
                     /locus_tag="VW749_001045"
     CDS             complement(1275..3380)
                     /locus_tag="VW749_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0175093.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            complement(3989..4969)
                     /locus_tag="VW749_001046"
     CDS             complement(3989..4969)
                     /locus_tag="VW749_001046"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0175094.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(4971..7223)
                     /gene="pbpX"
                     /locus_tag="VW749_001047"
     CDS             complement(4971..7223)
                     /gene="pbpX"
                     /locus_tag="VW749_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0175095.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(7227..7544)
                     /gene="ftsL"
                     /locus_tag="VW749_001048"
     CDS             complement(7227..7544)
                     /gene="ftsL"
                     /locus_tag="VW749_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0175096.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(7556..8506)
                     /gene="rsmH"
                     /locus_tag="VW749_001049"
     CDS             complement(7556..8506)
                     /gene="rsmH"
                     /locus_tag="VW749_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0175097.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            8672..8866
                     /locus_tag="VW749_001050"
     CDS             8672..8866
                     /locus_tag="VW749_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175098.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8882..9424
                     /locus_tag="VW749_001051"
     CDS             8882..9424
                     /locus_tag="VW749_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0175099.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            9435..9677
                     /locus_tag="VW749_001052"
     CDS             9435..9677
                     /locus_tag="VW749_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175100.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            9688..10023
                     /locus_tag="VW749_001053"
     CDS             9688..10023
                     /locus_tag="VW749_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175101.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(10133..11134)
                     /locus_tag="VW749_001054"
     CDS             complement(10133..11134)
                     /locus_tag="VW749_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0175102.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(11194..13095)
                     /locus_tag="VW749_001055"
     CDS             complement(11194..13095)
                     /locus_tag="VW749_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0175103.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHYSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(13117..13410)
                     /locus_tag="VW749_001056"
     CDS             complement(13117..13410)
                     /locus_tag="VW749_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0175104.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(13410..14228)
                     /locus_tag="VW749_001057"
     CDS             complement(13410..14228)
                     /locus_tag="VW749_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0175105.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(14215..14994)
                     /locus_tag="VW749_001058"
     CDS             complement(14215..14994)
                     /locus_tag="VW749_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0175106.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(15009..15500)
                     /locus_tag="VW749_001059"
     CDS             complement(15009..15500)
                     /locus_tag="VW749_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0175107.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(15511..16701)
                     /locus_tag="VW749_001060"
     CDS             complement(15511..16701)
                     /locus_tag="VW749_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0175108.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(16713..17147)
                     /locus_tag="VW749_001061"
     CDS             complement(16713..17147)
                     /locus_tag="VW749_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0175109.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            17421..18236
                     /locus_tag="VW749_001062"
     CDS             17421..18236
                     /locus_tag="VW749_001062"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0175110.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            18255..18896
                     /locus_tag="VW749_001063"
     CDS             18255..18896
                     /locus_tag="VW749_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0175111.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            18927..19928
                     /locus_tag="VW749_001064"
     CDS             18927..19928
                     /locus_tag="VW749_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0175112.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            19938..20567
                     /locus_tag="VW749_001065"
     CDS             19938..20567
                     /locus_tag="VW749_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0175113.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(20946..21331)
                     /gene="tnpA"
                     /locus_tag="VW749_001066"
                     /pseudo
     CDS             complement(20946..21331)
                     /gene="tnpA"
                     /locus_tag="VW749_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(21684..24763)
                     /locus_tag="VW749_001067"
                     /pseudo
     CDS             complement(21684..24763)
                     /locus_tag="VW749_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            24986..25462
                     /locus_tag="VW749_001068"
     CDS             24986..25462
                     /locus_tag="VW749_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0175114.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(25684..27897)
                     /locus_tag="VW749_001069"
     CDS             complement(25684..27897)
                     /locus_tag="VW749_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0175115.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(28298..28474)
                     /locus_tag="VW749_001070"
     CDS             complement(28298..28474)
                     /locus_tag="VW749_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175116.1"
                     /translation="MSLDIDKEKMTIMGIDFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(28854..30200)
                     /gene="celB"
                     /locus_tag="VW749_001071"
     CDS             complement(28854..30200)
                     /gene="celB"
                     /locus_tag="VW749_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0175117.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVIIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDVFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(30280..30786)
                     /locus_tag="VW749_001072"
     CDS             complement(30280..30786)
                     /locus_tag="VW749_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175118.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(30817..31131)
                     /locus_tag="VW749_001073"
     CDS             complement(30817..31131)
                     /locus_tag="VW749_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0175119.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(31141..>32160)
                     /locus_tag="VW749_001074"
     CDS             complement(31141..>32160)
                     /locus_tag="VW749_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0175120.1"
                     /translation="NFSSDFQLIEGLITHLMTLQVRLESRITLNNPLVDEIKQNYSDI
                     FFMTREILANMDKFLEWTISDDEVAYVSLHFLAAMERSKESTKFNILAICATGFGAAQ
                     MLRNRLETEFGKRVEVVDVIGYYELNQEKLKGIDFIVSAVDLSNLYFQIPVFKVSVFL
                     KSDEMEMIRKAMDQMQVSSYVQSSKINKFENNGFRQYFSKENFLICTESDKVNLLEKM
                     VESLSVGESNEFEQSLLYGIKQREELSSVVFSEKIAVPHPIQPFGTEGKVSVAICKDS
                     LLWDNQSSHVQLVFLLSPSIYGNEGLATVTKKIVSLTENDELQNQLISCNNFEDFINI
                     FEKIK"
BASE COUNT         9630 a         6946 c         5542 g        10042 t
ORIGIN      
        1 tccgaaaaat ttctccggtt tcttattctg aaagtgaaac agcaagagtt gatagagctg
       61 atagtggtgt ttcaagtctt gtgaatagct caaaagcttg tctaaaatct ctttattggt
      121 taagtgcata cgaaaagtag gacgataaaa tcgcttatca ctcagtttac ggctatcctg
      181 ttgtatgagc ttccagtagc gcttgatagc cttgtattca tgggattttc gatgaaactg
      241 attcatgatt tgaacacgca cacgactcat agcacggcta agatgttgta caatgtgaaa
      301 gcgatccaac acgattttag cacacgggaa aagttgtcta gctaaatcat agtaaggact
      361 aaacatatcc atagtaatga ttttgacgcg acatcggacg gctctatcat atttaagaaa
      421 gtgatttcgg atgacagctt gtgttcttcc cttaagaaca gtgatgatat tgagattgtt
      481 aaaatcttgc gcaatgaagc tcatctttcc ttttgtaaaa gcatactcat cccaagacat
      541 aatctcagga agacaagaaa aatcatgttt aaagtgaaag tcattgagct tacgaataac
      601 agttgaagtt gagatggaaa gctgatgggc aatatcagtc atagaaatct tttcaattaa
      661 cttttgagca atcttttggt tgatgatacg agggatttgg tgattcttct tgacgataga
      721 agtttcagcg accatcattt ttgaacagtg atagcacttg aatcgacgct ttctaaggag
      781 aattctagta ggcataccag tcgtttcaag ataaggaatt ttagaaggtt tttgaaagtc
      841 atatttcttc aattggtttc cgcactcagg gcaagatggg gcgtcgtagt ccagtttggc
      901 gatgatttcc ttgtgtgtat ccttcttgat gatgtctaaa atctggatat tagggtcttt
      961 aatgtctagt aattttgtga taaaatgtaa ttgttccata tgaatctttc taatgagttg
     1021 ttttgtcgct tttcattata ggtcatatgg gacttttttt ctacaataaa ataggctcca
     1081 taatatctat agtggattta cccactacaa atattataga accgtttttt tcagctggct
     1141 ccttcttttt tatcctcaaa attctatctt atactcaatg aaaatcaaag agcaaactag
     1201 gaaactagcc gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg tttgaatttg
     1261 attttcgaag agtcttaggc tttctcacga ataaccaaaa cgccatcttc catatctgct
     1321 tccagatgtt tagtatctaa atgatccaag tggaagtctg tcaccttatc acgaatttct
     1381 tgttcaacca cgcgacggag aggacgaacc cccatgactt cgtcgtaacc ttcttctgtg
     1441 atataatctt tagccgcttg actgactacc aagtcaatgt ctttcttagc caaggtttgg
     1501 ttaacttcag ccaacatcaa atctacaatc ttagaaaggt cttccttagt caattgtgag
     1561 aactcgatga ctgcattaaa gcggttgagg aattctggac ggaagaaggg tttcaaacgg
     1621 tccatcaatt ctggtttatc cgcatcttct gtcaagttgg cttcatagcc aaatccagca
     1681 tttgaggtcg caataatgac agtgttcttg aagtttactg tatttccttg accatctgtc
     1741 aaacgaccat catctagaac ttggaggaga agggtaataa cttgaggatc agccttttca
     1801 atttcatcca agagaatgat agagtatgga ttgcgacgaa cacgttctgt taaggtattg
     1861 ctattgtcat cataacccac atagcctgct gttgtaccaa ttagcttaga aacagctgtg
     1921 cggtcactgt attcagacat atccaaacgg ataatcgcat cctgggttcc aaacatatcg
     1981 agtgccaatt gcttagcaag ctccgtctta ccaaccccag tagaccctac aaagaggaag
     2041 ctgccgattg ggcgatttcc ttcatcaaaa ccagcacggt tacgacggat agcgcgagct
     2101 acagcttcta cggccttatc ttgaccaatc accttgtctt gcaagcgatg agccatatct
     2161 ttcaaacgtt cgatatctga agctcccatt tgcgatactg ggatacctgt cattcgttcc
     2221 acagattcag ccacatcgtt gacacttgca gtcactttca tatcttctgt gtggttttcg
     2281 attttctttt ccaattctgc aatgcgtgtt ttatagttta gagctgcttc aaaatcttct
     2341 gcttcaactg ctttttcttg cttgtctttt tccgtttcga tttctcgttc aacagcatgc
     2401 acatctgtta ctggatgttg agccgccaag tgagcagccg ttacatcgac aaggtcaata
     2461 gccttatctg gcaagctacg ttgaggaatg tattgaacag aataatccac cgctgctttc
     2521 aagacttcgt ctggcaagat gacattgtgg tgttgttgat agaggtcacg aattccttga
     2581 agaattttaa aagtattctc tgccgaagga gcattgacct tcacttcgtt gaaacgacga
     2641 gcaagagcag cattcttcaa gatggtgtta cggtattcgt cttgagttgt tgccccaatc
     2701 actgtcaatt ctccacgaga gagagctggc ttgagaatat ccgcaagtcc tttagaacca
     2761 ctgtctccac cagtgctacc agcaccaaga atttggtgaa tttcatcaaa gaagaggata
     2821 atattccctg cttctttcac ttcattgact aagttttgga cattttcttc aaagctacca
     2881 cggtattgag taccagcctc aagacctgag atatcaatag aaataatttc cttgttcttg
     2941 atagcagcag gaacatctcc gttcacaatg gcttgcgcta gaccttcgac aactgctgtc
     3001 ttaccaacac ctgcatctcc gaccaaaaca ggattgttct tggtgcggcg tgagaggatt
     3061 tcagatgttt cttgaatttc cttgtttcgt ccgataacag gatccaactt gccctcacgc
     3121 gcttctgctg ttaagtttcg acctagtttt gcaaggacac cgtcttgttt catacctgat
     3181 gcctgttgtg gcatttgcac atcagtttct gcatttcctg gtaattgacc agtcgcacga
     3241 tagtgagcaa attcctcagg tgtgacttcg cgtccattaa ttaagtaacg gcgattttca
     3301 gaactgtatc ctcgcatacc acccatcaat tggttaaata aatcatccat gttattaaaa
     3361 ttattaaagt tgttattcat attctttacc tctttttgtt tacttagtta tgattactga
     3421 tattgactat ctttgaccat tgttttaaaa aatttagact agctagatcg ctaccctacg
     3481 tactatttct ggtttttctt tttcaagcag gagtagacta tctttacttc tgaagatttc
     3541 tagatgaaac atagacccac ctctttctat tttactttaa ataagtgttc tagtaaggct
     3601 ttcatttacc ttacgttcat aatatactac attggtcaga aaaggtcaag agttttgact
     3661 ttaactgacc aatatttttt tacactcttc gaaaacctct tcaaaccaca tcagcttctc
     3721 cttatctaca acctcaaaac cgtgttttga gctgacttcg tcagttctat caaccatctc
     3781 aaaactgtat attaaaacga aataagaaca ggacaaatca atcaggacag tcaaatcgat
     3841 ttctaacaat attttagaag tagatgtgta ctattctagt ttcaatctac tatattttga
     3901 gcagcctaaa gttagctttc tagtttgttc tttgattttc attgtgtatt taaacacaaa
     3961 aacaccctga aacatcaggg tgccattctt acatcaaata taaaattgct agggtcagga
     4021 gacttgctag aagtcccact ccccaaaaga agaagtcaac cttccactcg ctccaaggat
     4081 ttcctttacc agacaatccc ccaagctcaa aatggtgatg tacaggcgtc atacggaaaa
     4141 tacgtttacc acctgtcagt ttgaaataac tgacttgcat cataacagaa gttgtttcaa
     4201 aaacatacac aattccgata atcaagagag tccattcttg gtggagagcc atagagatag
     4261 ctgccagcat cccacctagg gccaaacttc ccacatcacc cataaagacc ttggcaggct
     4321 tatggttaaa gatgaagaaa ccgagcaaac caccaatcat ggcaagaatc actagaagaa
     4381 tatccatctg accttgcaca taggcaataa ctccataggc agacaaacta atcacaacgg
     4441 aaatactagc taaaccgtca acaccgtctg tcaagtttac tgcgtttgaa aaaccgacta
     4501 gccagaaaag agcgaagaaa atatagaaaa atcccaaatg aactggataa ccaaagacag
     4561 acaggatatc gccaccgcgc tcatagaaaa gatagaagat aactccacct agaagctgaa
     4621 gagctaattt ttgcttagga ttaagcccct cattgatttt acgaaagacc ttgagaaagt
     4681 catctaaaaa tccgaccaag ccatacaaga ccaagatgaa caaaatcatt cccacattat
     4741 tgctgaattg gctactaaat agggcgaaaa agaaagcaac caaaacagaa gtaatcaaga
     4801 aaaccaaacc tcccattgta ggagtcccag cttttgcctg atgctgtttg acatcttcat
     4861 gcatctgctg tcctgtaatt tgcgcctttc tataaaattg gataaaggcc ggaattccta
     4921 ctaaagttag taaaaatgtc acaattccag cactgatgga aataaacata ttagtctcct
     4981 aaagttaatg taattttttt aatgtccttg atagctgtgt tagcacgaac atcttgcttc
     5041 tgcacagtag agcccgaacc ttgaaattca agttctatat tgagccactt agcaagggtc
     5101 tcagcagtct cctttgtcca accatacata tctggaactt cctctgcttt atcagataag
     5161 ataaggactt gctgattcgg ggcaagattc ttcccttctt cagcagaact gtttttaatc
     5221 ttcgttcctg ttcccacaac gatgggttgt acaagattgc gacgcaattc ttctgctaaa
     5281 tcaccaggtg aaatatcctt gacactaggc ataggataag gactttgttg acttacttgc
     5341 tccaaagctt tagctgttgt ttgaagattg agagagtctt tcatagctga agcccgctcc
     5401 aagataggat tggcaaattc tcccaactga atacctgaat aatgttcagg ttgttggacc
     5461 gtcacataca agataaaatc aggattttca gccggactca tcgatacagc cgagaaaata
     5521 tagtcggtta ccccgactag ataaccacca tttttctcgt cagcaatctg agccgtacca
     5581 gacttgaggg ctacattttg cccaggaaca gttacagttg gcttgcctgt gctgtggtta
     5641 tacatggttc cataaaccgg atccgtccct accaaaacca tgttagtccg agttagacta
     5701 gctgcatctt tagaaacagg atttcccaca atttcttttt gagatttccg agcagtttga
     5761 tcatttggat cataaatggc actaataaat ttaggctcca gcatgacacc gtcattagca
     5821 atagctgtaa aggcacgaat catttgcgtc tgggtcactg aaatcccttg tccaaatgag
     5881 ctttgcgcaa tgttgacaat attatccgca ggaagctgac cagcatactc atccgtcaaa
     5941 ccgaaacggg tcggaactcc aaatttaaaa cgattaagat aatcaagcca ggtagcatct
     6001 cccatctttt gctcaaggag ggtcatccca acgttacttg agtgtgcaaa accttgagaa
     6061 aaagtcatca ttctgccacc agtcaatcct tcattaacgt cccaatctcg aatcgtggca
     6121 tctgcaattt ttaactcact actattaaag acttctcctc ctggaaaggt attattatca
     6181 atagcagcag ccaacatcat cactttcata gtggaacctg gctcatagtt actttggtaa
     6241 aggatatcac gccaaacaaa gtcctctgta atgccttctt ttgtatctgc atcaaaggtc
     6301 ggtcgttgcg ttgttgccag aatttcccct gttttagcac tgaccaaagt cgctgtcatg
     6361 tactttcctt ttaccttctc ttgaaaagca tccatctggg tttccataaa ggactggagg
     6421 gggctggaaa tggttgtata aacatcctta ccgtccatcg ttcgttggga aacttgttct
     6481 gttccgggta caatattacc cagacgatcc ttttcatagg taataatgcc gtctgtccct
     6541 gcaagaatac tgttcaagga actctccatt ccagaggttc ccagcaagct cttgcttcca
     6601 tcttcatttt catggagctg agctaggccg ataaaactag aagcaaattg tccgtttggg
     6661 taactacgat tgggactggt tgtaaaatca atccccttga cctctgcagc ttccaattct
     6721 tttttgatag acatcatatt ggcataggta atcccatttc cctttgctcc aaaggaaact
     6781 tgcttgagat taggttgcga gagttgctct cttacatagg attcttccat gtccaaatac
     6841 ttatgaaaga cctctgcaac cttgttaaat tgtgtttttt ctacgtaaag aatcttaccc
     6901 gttgctgact tatagttctc atcaatgacc gcatagacat tataggaggt tgcatcctca
     6961 gcaatcggga ctccatttcg gtcataaata gtcccacgtt tggcaggaac tgtacgggtg
     7021 gtttgatgaa ctttcttagc ttccttcgct aaatctgttc caaagcgagt gcctgtccca
     7081 ataatgaccg caaaattgac taaaaaaatg gcaaaaacaa agacagataa taaactcaga
     7141 ctttttccaa ctctgcgtct gttttcagcc ggcgatttcc gatttttggt cgcataacgg
     7201 attactcttt ttgtccactt catatcttac tccgctattc taatattttc attgtttaat
     7261 tgcaaatcgt gtgaattggc aatttctttc aaacgttctg cacgtaatag ttcattgacc
     7321 tcttgcttgg catcgtccaa ttcggttttc ttttcctcta tctgcgcatt gatttttgtc
     7381 aaatcattct gcacttgcaa gagcttggtc tgcataaaaa taatactaat ggctacaata
     7441 agagtggtta cagcaatgga aaagtaaaaa gctttttcca cacgcgaaaa ccgtttaagt
     7501 tgcatctgta gtatttgacc tgttttttcc attttttctg ccatcttttt ccctcttact
     7561 tgtgaatttt tctggccacg cgcaacttgg ctgagtgcga gcggttattg gcttctaact
     7621 cttccgcact tggcaagatt ggcttacggg acaccaattc catcttgggc ttgagatcat
     7681 ctgggatgaa aggcaagcct tttggaactt caactgttga agcttccttg aacaattgct
     7741 tggtcaagcg gtcttctaag gaatgaaagg taatcactga aattctacca tccagagcca
     7801 acatatccat agcctgctgg atggactcat ctgccgcccc cagttcatca ttgacttcaa
     7861 ttcgaatagc ctggaaaatc tgcttagcag gatgcccctt cttcttgagt tccttggcag
     7921 gtttgaccaa cttgataatc tctgctaact cagtcgttgt ctcaatcggc ttcacttcac
     7981 gcgcttgctc aatcttacgc gcaatctgtt tagagaattt gtcctctcca tacttgaaga
     8041 aaatacgaac caagtcatga tagtcataat tgttcaccac ttcatacgct gtcagactag
     8101 catcctgatt catccgcatg tccagtggcg catccttttt ataagaaaaa ccacgctcac
     8161 gctggtctaa ttgaggacta gacactccca agtcataaca aattccatca atttcctgaa
     8221 caccagcttc gcgcaaacgt gcctgtaaat gacggaagtt gtccttgata aaggtcacca
     8281 ttcccttctc aatgtaaggt gccaagcgtt tttgcgcatt gtcaatggca ttctgatcct
     8341 ggtcaaaggc atagagatgg cctttttcac ttaatttact taataaatac tcgctatggc
     8401 ctgctccacc caaagtcgca tcaacgtaga taccgtcagg ttttacgtca agcatatcaa
     8461 tcgtttcgtg gagtaagacc gttacatgat gaaattcttt tgtcatatct tatctatttt
     8521 accacaaatc cgaccagctt gcacttgtca gacaaatagg acaaggagac tactatttct
     8581 tcaaaaaata tgtcaaaaat acttgacact ttatgtttaa aagactataa tatagtcaaa
     8641 tatatacgac ataaatcaga aaggagacca gatgaatcgt gtgaaagaat ttcgcaagga
     8701 attgggtatt tcccagctcg aactcgccaa ggatatcggt gtctcgagac agactatcaa
     8761 tatgattgaa aacgacaagt acaatccaac cttggaactc tgtctcaatc tcgcccgcag
     8821 cctccaaact gacctcaaca gtctcttttg ggaggaagat ttttaaaaaa ggagcaaact
     8881 catgaaaaaa gaaaccttca ctgaaaaact gatcaaacgc acatacggta tttctggtcc
     8941 ccttgacgaa tacaaacggc gtgaggccga tagtattggg aaccaagtct ttatcgtcct
     9001 cttttatctg atgattttcg gaaatattat tccactcctt ctggcctata aataccctca
     9061 agaagtggct ctaatctatc ctcctctgat tttagtgatt gccctcatcg cttctggcta
     9121 tgtcacctac caaatgaaaa aaacaggcat cacagtcatt gaaccagata tgctgaatga
     9181 gaaagaaagc aagcaactac actaccctgg tctgaaagca ggtttgttct ttggtctatg
     9241 gatgtttttt ataactcctc ttctcagtat actcatagat gaaggtcagg actattttca
     9301 ttctcttctc actataagaa atggtgtatc aagtattctc ggttctattt tcttcggagc
     9361 gagcatacag ttcctcatct cccgtcgcat tgcaaaaact aagaaaaatc aagatgagga
     9421 ttaggaggaa actcatgaaa aaagaaaaga aacagttacg ttatcctggt ctgaaagcag
     9481 gttcgattta tggaacagtg atatttttta taattccact cattgatacc ctaacaagtg
     9541 aaaatccaaa ttttatcagt tctcttctaa atacaaaaca tatttttaaa actatactgg
     9601 gagctttctt tttcggagtg atgatacata ttgtcgactc acttcgtatt gcaagagcta
     9661 aaaaagacca ggattaggag gtgccttatg aaatcactag ctagactact gatcattcat
     9721 gtttttatca gtattttcct tttcttcgcc cttacttcag gagctatttc tcatacagtt
     9781 ttactactcc tactcctctt tcttcctgcg ctcaataaag gacttgagaa aatacaatca
     9841 aaacggatac ctgtcctcaa cgcagccctc ttctttctcc tcatatcctt tccacaactt
     9901 ttaaccaacc ctgtccaatg gaaattttca atattcctag tcgtaaccat catttcaagt
     9961 ttggcctact tctataactt ttatcaagta gttaaagaag tagatcaaaa acagttgatt
    10021 taggagcttg ctcccataat ttctcatttt ataggcaaat aatcccacct agcttgttct
    10081 aggtgggatt attttatttc ttaacagaga ttgcaagtca ttttccttca ttttagaaag
    10141 tcgactcttt ccaattcaca ctacaatcca agacttgttg cctttcttct tgattgcgac
    10201 cttcaatctg gtcaatcaaa atctttgtag cctgttgtcc ttcctcaaag gagggctgaa
    10261 ccagcgtcga aacacttgga gaagaaaagc aagtccactc cgtattgtca aaaccaatca
    10321 acccaacttg cggcaagtta taattcaact ctttgataac ggtaaagact agaggtaggg
    10381 cccaacagtt agggataaat accagagttt tttcatcggg atcgatttct ttttgtaaaa
    10441 attctttaat ttgttccaaa ttcgtatgct tatcttcaat ggttagactg gcgtgacgca
    10501 tattagcatc tgttaaagca tccacaaaac cacttgcccg ctcaatccga gtactcaaac
    10561 gactcgtatc cgctgtaatc aagagaaaat gttcataacc tttttcgata caggactggg
    10621 tcatgtcata aacggcatca tagttattgg ttttaaccca gctagtccgg tgttcataga
    10681 gctgactatc aaaaaagacc attttcttct ttttctcatc gatgatacga gaatattttc
    10741 ggaaattaga ggtcggctga ataataaagc cgtctactcc caagagaagc atgctttcaa
    10801 tataccggtc ctcactctct tggctgtaat tactatttcc tatcattacc tggtagccat
    10861 tctggctggc gatatcctca attcccttaa caatttggtt tgagaaactg ttggtaatat
    10921 caccaatcaa aacaccgatt aattttgttc gtttggagtt taagctacgc gcaacaatgc
    10981 tcggtttgta atttgtttca tgaataactt tttcaatctt ttcacgtgtc tcttgggaca
    11041 ttttttcata tttcccgttt aggtaaaatg acacggttgt tttcgaggtc tgagccattt
    11101 ccgcaatgtc ttttatggtc agtttcttct ccaatctaaa acacctccta ctaatactta
    11161 ttataacata ttcactattc aaaatgccta tttctagcac tgcaagcgaa tcattctctc
    11221 atttatttta tcatatacta gacattttcc acgcattttt gttccgtcaa cgaggcacaa
    11281 tttttcacct acacgaatat cctcgcttaa taacagaatc agcttgtctg tttcgtcatt
    11341 tttcacttca aaagccagag cattttccac ttcacgatca tctgtctggt agacagaatg
    11401 acggatgatt tcaaaactct catgcgcaat gatggtataa tccagcatct gattctcaaa
    11461 gaattggcgc ttggtgagtt tgctacttct ttcaagctca ttgtatttag gagaaatgat
    11521 ggtatcttcc aaatcaaaat caacttcact ccatagtctc aactgattga ttttcccatc
    11581 ttgataggtc acatccttgt caaggataaa ctgagtcaac gcctcatgct gaccttgaca
    11641 cctgatgtca tctaccaaga gccagacatc ctctaccaac atgaggattt ttctcttgtg
    11701 aagataaggc aaatcaggtt ctgctgacca ataagcccct tcaatataat gcactccctc
    11761 cctttcttta tggtgacaaa acagggagtg aggatagtat tcatattccc aggatcccgt
    11821 gattctttcc ggagctttcc catctacaat gcaggtcgaa tgactccaag cactctttaa
    11881 gagataacgt tcatatatct cccgataaga ataacgccca gcatctatga aaataggttg
    11941 gccttgatac tgtaagcaaa aactattctc gtcactatgg ctatgggcac ttcctagcgg
    12001 accatttttg aaaaatagat aacgatgttc atccttaatg cagacatgtc cagagtcttc
    12061 aaagatcatg gacttaggct gccaagctct cctttcaaat tcctgcagtc gcttgacctt
    12121 ttctcgcccc aggaacaaga ggctaagcaa atcgacttta acatccagac cgttaagaag
    12181 gtcttccttg ttcaaaacca cagcagacag actcaaaatt tctgtcgttt ctgtagaatc
    12241 gctatcacca aaagccaaag ttcgtccatc taagcctgtc atcatttgaa tataggtcgc
    12301 catcttttcc agcaactctc ggtaactatc ttgcaagtct ggaagcaaga gacacaaatc
    12361 cagcaaggct ttataaacct ctacatgata gagaatcgac tgttcaaact ggcttccatc
    12421 tcctaaaatc tgtgtctcaa tttgctgttt caactcctct gaagcaaaat ggtaagcttc
    12481 ttctagatcc atcttatctg aaaagaaata atagatagca agcatcggaa ttgtttgtaa
    12541 aatcccccag ttactaaggg tgtacttggc gcgatagtgg cttttcataa agtcaatctg
    12601 cttttctaga ctgaccaaaa ttttctctag ttctttctcc tctagcaagt caaatttcaa
    12661 gaggagcaag agtagtttca accaagtaaa ggaacgaata cccgtatcca aggttctagt
    12721 catcaaggat tgaggagaaa attctctcac ctgctcaatc caatcaaata gaaagaactt
    12781 gcacttttga atatagctct tatctccttc taccacatac cctatcataa actgcaagag
    12841 atattcttgt cgattgagca tataagccca ttctggatca tcttcaaata cttgatccca
    12901 taccatcggc tggatttgat ggatttttga acaaggctcc atatcccaag gactatcaaa
    12961 cataaaacga ttgtccatca agcgttcaag ggaacgcttg actttctcat agtcttttga
    13021 atagtgggac aagatataat cacgacattg gtttccatcg attctttcaa aaaattgtct
    13081 tctttcttct ttcattatct attaccagaa aaagaactac ttaaaaagca gttcttttgt
    13141 ctttcccatt acactttcct tttctacata gatgaccaca ccttttgcaa tctgcaagga
    13201 gaccaagtca tctttgatag aaatgatttt tccatgaatt ccagacaata acaacacttc
    13261 atcaccagat gttaaagaag ctaaatactc ttgtcgttgc tccatctgtt tgcgaagcaa
    13321 cttttgctga cgaatagaat gaaagcttga cagtaaaagg ggactcactg ccaagacaat
    13381 cactattcca taaaacaatg ttgtatccat taagctataa tcttaagcca gcttccgata
    13441 attccgatga taactgttaa aataacgagt ttatatgttg tccatttctt ttctttgatc
    13501 aagtagtaaa ctaaaagtgt aaatagggct ggtagaagag ctggagcaac cttatcaagc
    13561 attccctgaa tacttacgat actttgttta gcgtctgctt taacttcccc tgcagcaaag
    13621 gtaatcggca ccataatctt aacagatgtc gctgccaaac cagcaattac ggttacaccg
    13681 ataatattgg caatacgaga aatcgttgcc atctgctcgc ttagtttatc aatcacagtt
    13741 gttcctagtt tgtatccata cagaccagtt gacaatttaa tcgctgttaa aatcgtattc
    13801 atcgcaagga agaacaagat tggaccgaca accaagcctt cttgagcaaa cgaagctgcg
    13861 atggttgaga acaatggagc taaacagaat tgagaaagag aatccccaat acctgccaat
    13921 ggtcccatca aggccatctt gatgctacgt gtttcttttg ttggtcgacc attttccaac
    13981 attacaagat gcaagctggt aataaaaggc aggaagtgtg ggttggtatt atagaattca
    14041 cagttttctt ccaaggcttg gtagaaacct tcctgatcct ctccatagtg ttttttcaaa
    14101 gcaggataca tcacattggc atatcccaac ccttgatagt tactatagtt aaatccattt
    14161 tgacaaaaga atgcccgcaa agacgtttta agataatcac gttttgttaa tttgttagat
    14221 ccagtcatcg tgtgcttcct cctctaccac atgatccgct gtttttggct tgttataaaa
    14281 ttcaatcaaa gcaaagatag tacctacaat tgcaatacca attgttggga tgtttagata
    14341 agctgcacaa acatatccca acaagacaaa gggaatcaac tctttcttag ccatcactga
    14401 caagatcatc gcaaaaccga tagctgggag cattttacca gcaactgtca aacctgtaag
    14461 taataccggt ggaatgtagt ctacgagttt caacaaggta tccattgaaa gggcacccaa
    14521 gcaacccaag gtaaatccaa taaaggcaaa caaccaaatt gttgcattta gagtgaactt
    14581 aaatttcttc aaattatggt ttttcaagtg cttcatcgct gtttcaggcg caccagcacg
    14641 tacagtgtag gcgaaagttt gtaagaattg aatcgccaca gcaatcggag tagagagggc
    14701 aagagccgct tctggactga ctttaccagc actagtgata gccatcaagg taccaaagat
    14761 accaggtccg attgggtttg gtggaacagt acctccagca cctacaccga atcccatata
    14821 agccaattca ccaatagctc ccattgcaag agcagtaggc agatcaccta gaataattcc
    14881 gacaccaaat gacagaacaa tacatctatt ggtgtaaatt cctaacagca ttccactaaa
    14941 acagaaagct gtccataatc caattaaaat cgcttgaaat acattaatcg acataacgat
    15001 ctcctctttt aaatatagtc cataatgttg acttgaacag ctccatcatt tcctgttgga
    15061 gttgttttcg tattaaatgt tacttgatga gtttggctca attccttgag ggctgccttg
    15121 tcctcttcac ccaggaagat ggagcgtgtc acttgctctt taccaggggc attgtgaatg
    15181 ttcccaatat tgatttcttt gatagggaca ccaccttcta ccaaggttaa agcgtccttt
    15241 acatccttta caacgataaa gatcgtttga gcaggattag ccttgtgaat gatatcaatc
    15301 accttttgca aagggaagaa acgcatggca actgagtctg gcacaactgt tttcatcaga
    15361 gtttgttgca tcttgtccgt gcttacttcg tcattggcaa caatgaccgt attacaacct
    15421 aggtatttta cccaaagttg tccttgtcca tgaatcaacc gttcatcgat acgggtcata
    15481 ataatatttg gcattgtcat atttctcctc ctaccaatat aggttccagt ctttgtagaa
    15541 acggataagg gcttctaggt aatagtagtc accccagata ttgccttcat ccactccttt
    15601 acctgaatgc catgagtaca caccgtggag gagacttgtc ccaccagggg taaattgatc
    15661 atttgcataa tgttcgatca aggaacgaag catggcatgc atagcatgtt tataaatatc
    15721 tttgtcagca tccacctctg ggagatgttt tagcatttca tgaatcccac agacggcgat
    15781 agctgttgct gaagaatctc gtgattgatc actaccatca ttaaaaatca aatcccaata
    15841 ggacacatga tcttttggca gacgattcaa gaaataattg gtcacaccct taaacaagtc
    15901 aaagcaggac tcgtctttta agtgacgata agtcaaagga ataccataga ctccccatga
    15961 ttgaccacgt gcccagcatg aatcatcact atacccttgt ctcgttacac ctttaaaggg
    16021 ttgacctgtc tcaggatcaa aatagaaggt gtggaaggac gaagcgtcat cacggattac
    16081 attattagct gaagcataga aatgactttc tgcaatatcg tagtattttt gatcacctgt
    16141 ttcttgataa gcaaagaata agagttggat attgagcaag cagtcgataa tcaaacggta
    16201 atgctctttc ttgcccaagt ctccccaagc ttgaataaaa ccaccttttt cttgatagcg
    16261 ttcaatcaac ttatctgcag ctttcaaggt tgcttctcta gcctctccat ctccatttat
    16321 cttatattca gccatacaag acggtgtgta caagaagccg agatcatggt gatccaattc
    16381 tactctctta ttgacacgat ccaggaaaga aagaacattt ttatgagcga tgtttttaaa
    16441 tgcatcctgt tgactgtatt cataagccaa ccacagttct cctgtccaga aaccattggt
    16501 ccattccgtg ttatccatga ttggatagac attatcaaag gtagctggcg tcgggaaatc
    16561 ttccttgaaa tagtcaaggt tgagttctaa ctgccgaata accttatcga ttgcctggcc
    16621 gacttcttct ttcgtcagaa gtggtacttc taagaagcgc tcaggcgatt ttattttttc
    16681 aatcgtaacc ttttttatca ttcttttacc ctttaaatac ccgattcgaa atcttcttcc
    16741 tcttcctctg catccgttga aaacaattct ttaccattta cgactccgcc ctgggccgcc
    16801 actactgatt tattaacaac ctcatcaaag ctatgagcca ttctagcaaa gactgcttcc
    16861 attaacatgg ctaagttcaa acccgagaga acattcattg ttttggctgg attttctccc
    16921 attatggtag aagaaacctt gaatggcgat cctcccaaga gatcacttag gattaaaact
    16981 tcttcttcat ttgaaattgc aagtaagatt ttttgcttga gttcatctgc tgacattcct
    17041 tccacaaagt caatcgcctc cacattttct tgattgcctg caatcaattg taaagaacta
    17101 taaatccctg tagcaaaatg tccatgccct acaagtacaa ttttcatctt ttctcctttc
    17161 ttgtttaggt ttaccggttt actttatatt ccccattgta atcctttatt tttatcttgt
    17221 caatagtttt ttaaaaaaaa aatattagcg ctttcattat ctttttaacc attttaatag
    17281 gcagaaattt caaaatcttc cgttttttta ggaaaacaaa cctttttata aataaaaata
    17341 tttatttatt gacaaaaccg gtttactaga atataatttg gttatagaga agtcttaaca
    17401 aatttgaaag gaagtatcaa atgacaaata catcattctc aattgagcag ttttctttaa
    17461 aaggaaaaat tgctctcatc accggcgctt cttatggaat tggatttgct attgccaaat
    17521 cctacgctga agccggcgct actattgtct ttaacgatat caatcaagat ctggtcaata
    17581 aagggattga agcttatcgt gaagttggca tcgaagccca tggatatgtc tgtgacgtga
    17641 cagacgagga cggtatccaa gccatggtca agcaaatcga acaagaggtt ggtgtcattg
    17701 acatcctcgt taataacgct ggtattatcc gccgagttcc aatgtgcgaa atgagcgccg
    17761 ctgatttccg taaggtcatc gatattgact taaacgcacc atttatcgtt tcaaaggcag
    17821 ttattccttc tatgataaag aaagggcatg gaaagattat caatatttgt tcgatgatga
    17881 gcgaactggg acgtgaaaca gttagcgctt atgctgctgc taaagggggc ttgaaaatgt
    17941 tgacccgcaa cattgcgtct gaatacggtg gagccaatat ccaatgtaac ggaattggac
    18001 cgggttatat tgccactcct caaacagcac ctcttcgtga gttgcaagaa gatggttctc
    18061 gccacccatt tgaccagttc atcattgcaa aaacacctgc tgcacgttgg ggaaatcctg
    18121 aagatttgat gggccctgct gtctttctcg ctagtgatgc cagcaatttt gtcaatggcc
    18181 acatcctata tgtagatggc ggtatcttag cctacatcgg aaaacaacct gagtaaaaat
    18241 agaaagaaga tcttatgaaa atcgcattaa tcaatgaaaa tagtcaagct agcaagaatc
    18301 acattattta cgatagtcta aaagaagcga cagataaaaa agactaccaa ttatttaact
    18361 atggtatgcg tggagaagaa ggagaaagtc aattaactta tgtgcagaac ggactaatgg
    18421 ctgccatcct tttaaataca aaggcagttg actttgttgt taccggctgt ggtacgggtg
    18481 taggggctat gcttgcttta aacagcttcc ctggtgttgt ctgtggtcta gcagtggacc
    18541 caactgacgc ttacctttat tctcaaatca atggtggtaa cgccttgtct atcccttatg
    18601 ccaaaggatt tggctggggg gcagaactga ccctcaaatt gatgtttgaa cgcttatttg
    18661 ctgaagaaat gggcggtggc tacccaagag aacgtgtaat ccctgaacaa cgtaacgctc
    18721 gtatcttaaa cgaggtgaaa caaatcaccc acaatgattt gatgaccatc cttaaaacaa
    18781 tcgaccaaga cttcctcaaa gacaccatct ctggcaaata cttccaagaa tacttctttg
    18841 aaaactgcca agatgatgaa gtcgctgctt atttgaaaga agtattagcc aagtaaagct
    18901 attctaaacc agaaaggaac taatggatga cgaaaatatt actgtttggc gaaccattaa
    18961 ttcgaatctc accattagat gccaccagta tcggcgatca tgttgccagt tcgacttatt
    19021 ttggcggatc agaaattaac atcgcttgta atttgcaagc cctgggtatc tcaacgaaag
    19081 tctttaccgc actccctgcc aacgagattg gagatcgttt tctcacattc ttgaaacagc
    19141 accaaatcga taccagttca atctgtcggc ttggcgatcg aatcggcctc tactatttgg
    19201 agaacggctt tggttgtcgt caaagtgaag ttttctacga tcgtaagcat acgagtatca
    19261 gccagattcg gccaaacatg ctagatatgg attctctctt tcaggggatt agccattttc
    19321 attttagtgg aatcaccata gctatcggtc aagaggtccg tgcgatcctt ctcctactct
    19381 tggaagaagc caagcgccga ggaattgtcg tttcaatgga tctcaatctg agaacaaaga
    19441 tgatttcagt cctagaagcc aagtatgaat tttctaagtt tgcacgtttt actgactatt
    19501 gcttcggtat tgatcctctc atgattgatg accaaaatct agagatgttt ccaagagaca
    19561 gtgctagcct agaagaggtg gaaaatcgca tgcgactttt aaaagaagcc tatggtttca
    19621 aggccatttt ccataccctc cgatctagtg atgagcaaga caaaaatgtc tatcaagcct
    19681 atgctctgga agaacgattt gaagagtctg tccaactaaa aactgcagtc tatcaacgaa
    19741 ttggtagcgg ggatgccttt atatctggtg ccctttacca actactccat cattcctccc
    19801 taaaaactac cattgacttt gcagttgcga gcgcaactct caaatgcact cttccaggag
    19861 accatctctc cacttccgca actagtattg aaaatttact ggcaaatgca caagatatca
    19921 ttcgttagga gaattacatg accaaatcag atacgattat tgaactaaaa aaacagaaaa
    19981 ttgtcgctgt cattcgagga aatacaaagg aagaaggact acaagcctcg attgcttgta
    20041 tcaagggcgg tatcaaagct attgaaatcg cctataccaa tcagtatgca ggacaaatca
    20101 tcaaggaact tgtagacttg tatcaggacg atcagagtgt ttgtatcggt gcaggtactg
    20161 tgcttgatgc cgtaactgct agagatgcca ttctagctgg agcaaattac gttgtttctc
    20221 catctttcca tgctgaaact gcgaaaatgt gcaatctcta cagcacaccg tacattccag
    20281 gctgtattac cctcacagag atcacgactg cacttgaagc cggtagtgaa atcatcaaac
    20341 tcttcccagg tagtactctc agtccagcat atatctctgc agtcaaggca ccgatcccac
    20401 aagtttccgt aatggtaacc ggaggagtcg gcctaaacaa catccctcaa tggttcgctg
    20461 ctggtgcaga tgccgttgga attggtggcg aactcaataa actcgcttcc caaggcaact
    20521 ttgaccgcat cagcgagatt gcccaacagt atattacact cagataaaat cataactacc
    20581 cgtctaacgg gtggtttatc tcagagctat aagcccaaat catcagccag cgcctaaaga
    20641 cgctggcttt cacgttgttc aagccttatt gctcttgact cgtcacttgc ctctttaaga
    20701 gactttggta ttacttacca ctatccctaa agggatcctc atattctttt acactcaatt
    20761 tatctagtgc tatagtagat tgaaactgga atagtatacc tctacttcta aaacattgtt
    20821 aaaaatcgat ttgactgtcc tgatcgattt tgtcctgttc ttatttcatt ttactatata
    20881 tcatacttta ctagttctca aattttcata ctcgtgaaga aatcatccac tcgataattt
    20941 ctttaatctt gactatattt cttaattgtg gcttcattaa gccctactgg acttacataa
    21001 taaccttccg cccagaaatt ccgattccca aacttgtact tgagattggc gtgtttgtca
    21061 aacatcatga gtgcactttt gccttttaaa taccccataa aacttgaaac acttagcctc
    21121 gacggaatac tgactaacat gtgtacatgg tctggcatta agtgaccctc gatcatttca
    21181 acacctttat aactacacaa gcgatgaaat atttcgccta aactacttct atattgatta
    21241 tagatgactt ttcgtctata cttaggggtg aacacaatat gatagaacac atccactttg
    21301 tgtatgataa actatgagtc ttttgtgcca tattttttct cctttcgctt tacaattgga
    21361 ttgaatacct ttattgtatc gcgtttggag tttttttggt ataaccttcg acgcgcacct
    21421 cacggagcga gacggactta tatagtggag tgaaatagga tacgaacaaa ttgattagga
    21481 aaatcaaatg aatttataga aatcttttag cagttataac gttctattct agtttcaaaa
    21541 cgctatagtc acataataat gaagtaaaaa aggataagta tcaacttatc cttttttaaa
    21601 agaaaaatcc gaagatattt ggccttcttc ggattttttc tattttccac agtttcatgt
    21661 aattcatcta gatgatgaac aaattagttg ttctttcctc tacggaatag ataaaatgcc
    21721 ccaagtagca agaaccctag acttgccaag attgactgac cttctcctgt ctgagggaga
    21781 ttcttttgat ccgaatggtt cttttcctct tcagattttt ccttttcttt tgaattctgt
    21841 acttgtggct gagctgcttg ctctagcttt ttaaagactt cctgatctgg agctgattcc
    21901 tgggtttcag gattatagta ggcaatctta tattcatccc cttcttttcg aatggtatag
    21961 actccacgtt tcaaaacttg gaattggttg gaaatagtag agacagaatc atcatatttc
    22021 acaatgcccc aaactccttg tttagcatca taaacagact gaagggtttc gctattttcg
    22081 atgaggctac tttctaactc ttttatcatt tgattgaagg tggcacgatc cacgttagga
    22141 attagcatat agccataaga atctccattt tgcttatgag cctgactaat cgtaagaaat
    22201 tcattttcaa cttccttgtc tgactgtcct tcattgatat ccttccaggc tcccttttgc
    22261 aaagccttac tcatactgat tgaactcttc ttaaagaaaa agtaaccaat attctttttc
    22321 gaatcggacg attctaaaaa gacactttgg gtttcaggat aatccttttc ttgttctgta
    22381 agggaggctt ctttatcatt gacatagact ttatatggat tacttgattc cagttggtga
    22441 aatccatggt tgctgtcgca ttggcatcat ctagtttgct cgttccaacg aaagcagacg
    22501 gtagaacttt acctgtatcg ctatccgctc tcttagcatc cgtctctgtt gtaccaggca
    22561 tcttatatgg attaactgtt ggccagtagc catcgctata gtgactcaaa tcgccattgt
    22621 aaagatagaa catcccatca ctcgtatacc aaccatgttt attttccttg ttcatgtgtt
    22681 cgtaattcaa ggtacgactg gaaaagagtg acaagccaaa tccaaaccct ttctctgcat
    22741 tgtacatggc tgttttatcc atcttgttaa aggcagatag gtaacttgtt cttggaacac
    22801 ttgcgactcc tgcatcactt aacaaggatt gcatcaaact gatatcctta taagtcttca
    22861 aattcttaaa gacatcataa taactatccg attgaacaat ggtcttcaca agactctgca
    22921 aacgttgttt ggtttctcct tcagacatat ccgctattcg gtgaatccct cttagtactt
    22981 ctactgcggc cacgtgcccc tcgctatttg cacgactgat cgagcgtcca cgactcatat
    23041 ccatcagctc tccattcacc agcaaaggag caaacgattt atcaatccag tggtacatgg
    23101 tttgcatttt atctttatcg attggattct tggtcttttg aatgactggc aacagttgag
    23161 acaggccatc aatcaaaaca ttcccataag cacccgtata ggcaacattg gtatggtcga
    23221 tataggatcc atcttgataa aaaccttcac cttggtctac caacttgaac acttgctcaa
    23281 tcgagcgaat ggtagaagaa atttcttgat catccttacg cagtaaacca gctattactt
    23341 ttactcttcc catatcaact aagtttccac ctagagcctt aaatgggtta tcagtcgtct
    23401 ttcggaaatg ttcgggatct ggtacaaatt tttcaatcac atctgtatat tttttaattt
    23461 cctcatcaga gaagtattct ttcatcagag acaaggtatt gttgatggca cgaggtgtac
    23521 cgatttcata atcccaccag ttcccaacaa tgctcttttc actattgtag acatgtttat
    23581 gcatccattc catggaatcc ctgactgttc gaacgacagt ttcatcttga taataacgag
    23641 aagaaggatt ggtcacttgc ttggccatct cctccaattt ccgataagtg gcagtcagat
    23701 ttgcagacat tttataattt gaaaattttt cccacaaata ggtgcggtcc gcctgacttg
    23761 aaatactaga taggctatca gctacctttc cttccaattc ctggtttaat ttggccatct
    23821 gttcattttt agaatcatag tattgattcc cagcaatgat gccattccag tcatccaaac
    23881 ggtctgtgta tgcatcctta acagaggcta gaatcttcaa aggaatcttt ttcacttcct
    23941 tgccatcttt actgacaatg acattggttg tcccttcctt aagaggttct aaaattccat
    24001 ttttgactga agcaacgtca ggattttcta ccttataagt atagtccgca agagaaaaaa
    24061 catgtttttt tccaattggt aaatcaatct tttcctcaag ctgtttatct gtttgagaat
    24121 cctcagaaag ctgggctgct acctctacca gctcaatatc cttaaaggaa acagtcccag
    24181 ttcctgtttc atagaataac tccagcttga ttttatcaac atctaaagtc gggctatagt
    24241 ctgcttcaat ggtctgccag tcctttgttc ctgacgtcgt tgcagaattc cacaatcgct
    24301 tgtccttacc actttcctca atgatacgaa ctttggcaat cccgacttta tgatctgttt
    24361 taatcttgaa acgcagttta tactttttct tagcttcaat aggaaccata cggtgaaccg
    24421 ctgcccttaa tttctcaggg cttgagatag tgatagcccc atccttagcc tcaatgactc
    24481 gagttgaggc atctgcagaa ctattcttct ggtctaccca agctgaccac ccctgagctt
    24541 tgcttcctgt ccacggactg cttccgtcct ccgtctgacc aaaatcacca ttttcaacta
    24601 aattttttgt atccctttgc tgatactgaa cttccttctg gctttgctga atggtattcg
    24661 tagtcgtttc ttccgctcca actgtcatat aatggtttaa taaaaatcct gataaaacaa
    24721 gtgaagacaa actcacaatg agcttctttg tttttgtttg catgtataca ctccaataaa
    24781 catattgtaa aatcaatagg aactaaatct caaattagag atttatagca actaagtaaa
    24841 ccggtttaat taaattatac catttttaaa gttatttgta aacggtttct atcatattga
    24901 gggcttattc ttcaacaata tcttccatcc gactcgacga aaaaagtaaa aactgttaca
    24961 atgtagaaaa agaaaagagg ccctcatgac ttcactttat gatttttccg ttttgaacca
    25021 aaacaaccaa gcaactccct tggatagcta tcgtggcaaa gttctcttga ttgtcaacac
    25081 tgctactgga tgtggtttaa cgccccagta ccagggactt caagaactct atgaacgcta
    25141 tcaagatcag ggctttgaaa tattggattt cccttgcaat cagtttatgg gacaagcacc
    25201 cggcagcgca gaggaaatca acgccttctg tagcctacat tttcaaacca ccttcccacg
    25261 ttttgccaag attaaggtca acggtaagga agcagaccct ctctatgtct ggttaaaaga
    25321 ccagaaatcc ggcccactag gaaaacgagt cgaatggaat ttcgctaagt ttctcatcgg
    25381 tcgagatggg caagtctttg aacgcttttc ttcaaaaaca gacccaaaac aaattgaaga
    25441 ggcgatacaa actctactat aattcacaat ctcactatga ttaggtttcc tttaacctga
    25501 tgaatagtga gattttttga ttggctttga cttaaataga aaaacacccc atgatatgaa
    25561 acatgaagtg ttgtaaagtc tatgttgtag gtgcttattt cacattttca atgtgaccag
    25621 tgataacgaa taccatacag aatcttcata tacactaaac aaatgacttt ctaattatat
    25681 caattagttt tggctagtaa atatcatttc caacaaacgc cctctcaatt ccttatcctg
    25741 atgatgcaag atattcatta agtcatgaga gtttttcgca ttgatgaatt gatttaacaa
    25801 tctatctttt aattcatatg gaagagaagc tgtctttagt agtctaaaaa cttcatcatt
    25861 taaagatatt gttttattat ctttacattc aaatctagct gtatcattct tatttggtaa
    25921 ttcaattata gacacattcg ttcctttaaa atgaattcta tgccttctat tgcttggaac
    25981 gatactagaa tctccttgta atgttaactc taccatcccc atttcccaat cgattgataa
    26041 tcttgtttta tatctttgac cattttgatc ttcaagcatt tcaaaagaat gttgtttgcc
    26101 tgggaataca taccaatcta caacttcagg taaatcaaca cccatatcta tctcagaacc
    26161 aaccaaggga atgatcgcac cactttttgc aaacacaggt atagtcgaaa tgtctctata
    26221 aacactcaac ttcacaccac ctgtatattt tttctctgaa aagaagtcat accattcacc
    26281 ttcagggaac catacatcca cttttgcaga ttggaatgcc aagtccatct tttctacaat
    26341 gggagccacc attagttctg ttccaaaaaa gtattggttt ggaacattat agctctcatc
    26401 attctctggg tagaaataat acattgggct gattaatggg gcaccttcct cgtgtgtctt
    26461 tacattcata gtgtatagat atggaatcat ctgatgcctc aaacgaaggt atttcttcat
    26521 aatcttagat gttgtttctg aaaaaaacca aggttcttta ctattaaaag gacttctaga
    26581 actatgtaat cgagtgatcg gactaaaaac accaaactgt agccatctag tttgcagctc
    26641 ttcgtcataa tctcccagca tgtgcccacc gatatcatgg ctccaccaac tataaccgat
    26701 attagatgct gtcgctgtaa aataaggttg aaatcttaag gaattccaac taataatagt
    26761 gtcccctgaa aaaccaacag ggtagcggtg gctaccagga cctgcatatc ttgataaaat
    26821 caaaccacct tctgcatttt tacaactatc ctgataatga taatggttta aaagccatag
    26881 tggatccaat atgccttgag tcccttgttg ccagtcaatc caccaaaaat ctactccctg
    26941 cttttctagc tcataatgaa catctttaaa gtaggcttcc ctaaaagagg gattaaaaaa
    27001 atcaaaaatg gcaggttctt ctagttctac atttaaccct aatcgtttgg cgacttgagg
    27061 ataagcttct tcataagccc gtataccatc agcaggatgg acatttaaag agagttttaa
    27121 ctttctatca tgaagttgtt gcaataactg ttctggatta ggtattaagt ttttattcca
    27181 actatatcct gtccagccac ttccaaaacg agctggaatg tcagttatat gccaatccat
    27241 atctaacaca ccgatagata atggaatttt ctctgtttca aatctgtcta ttaaatccaa
    27301 gtattcatcc gacgtataag gccaatatct actccaccaa ttccctaaag catatcttgg
    27361 taacaagggt gttgaaccag tcaaatggta aaagtctctg attgctcctc tataatcatg
    27421 cccataggca aagaaataga ggtcaatttg attttctctc tcaatataac cagactgttc
    27481 atcccaaata aatccttgag aatcatccaa taaggctata ccatttcgac taataattcc
    27541 atcttctaat gggattgctc catctgcctt atccagagtc cgagctgttc cttttaacgt
    27601 ttcaatcgat tcaccaaaat accagcgact accatatacg gcaaaatttc cttttaattc
    27661 tataaataaa ttttcggcgt taaattctcc tttattaaag tgcagatgaa aatagtccgt
    27721 cataatatct agtacgtttg atgtctcgat ataatctaac gaaacttggc caaaatctct
    27781 attatagata agttgtgtag ttctatcctc aaaactgcca gttttagagt attctaacct
    27841 tactagcttg tctgttaata cagagatgcg ataaaactct cccttaaaaa ttttcaattt
    27901 gtttccctcc ttttatggta gcataaaaac agaacgcacc atttttgatg cgtttttcat
    27961 tattctgaat gcaatgttct atctgttata tctatgacaa ataatagtca attgaaaaaa
    28021 tgtagtggac aaaatatctt ttaacaaacc aagagtttat taaagagtta tcacttttca
    28081 acttttctaa gcttatgcag ttgtgaaaca aactactttt aaactattaa ctaagatagg
    28141 attgataaat aatttcaaac tcttactagc aatcatacaa tattcaagct cacgtgcttt
    28201 tttccttcct gcttatttct tagaactgaa gaacccggat cggtatataa attatccgga
    28261 tcaacatagt cataagattc ataacagttg cgcttcatta agtcatcccc agagcaagag
    28321 cttcatctcg taatttttca acatcactaa ccgtaggtcg ccatccttca atcatatttg
    28381 tacttaaagc ataccaaaca ctcttaaaaa cggatcggtt ttcaaaatct attcccatga
    28441 ttgtcatctt ttctttatct atatctaagg acatatgcta cctcctttag atacattata
    28501 ccatgtttct atgtagcttt taaaaatttt attttgtttg tcatatctaa gttttcagca
    28561 tgcttatcct attttataag cctcaaaccc aaatataaaa cgcattcttt ttgctttttt
    28621 actattgtat cgtattctac gataacatac tttactttat tgttttttta aaataacagc
    28681 agttccctgt ttatcaacta ttcgaactac tttctatttt gcttcatacc ctacatagcg
    28741 aaaaaatatg aaaaagcaga gaagaatatc ttaaaaagac ctcttcactg ctaatgttaa
    28801 cgctcattat ttaaactata tggattctat catcgagtat acttttttac ttattagata
    28861 ccttgctctt ctttcaccaa tttttgatca tatacacgga tgaatggaag atagactagg
    28921 aatgctgcaa atgcacatac tagagcaact aatacagctc gaagatctgc tgtccctaag
    28981 aaagctccaa tccctactgg agttggccat ggaacctgtg cgataattgg cttaataaag
    29041 tttagagaat tcgctacgta ataaatagta gcagtaacca ttggtgctaa aataaatggt
    29101 atagccaagg ctggattata gataataggt aatccaaaaa ttaatggttc attaatatta
    29161 aataaggctg gaactacaga tgctcgtcct attgctttaa gctgttcaga tttagaggca
    29221 aaagcaatat ataaacatag tcctaaagtt gcaccagaac cacctgcaat tacaaacata
    29281 ttagaaaatt cacctgcaac agcgaagtgc ccgccagcag cattttcagc catgttagca
    29341 agagcaattg gactaacaaa tgcaaaaaca atgttcgcac cgtggatacc tacaatccaa
    29401 agtagttgag tcagtaaata aataatcatt aaaccaatcc acgaattagt cagattggat
    29461 acaaaaccaa atggaattgc aatgacttta aaaacatctg ttcccattgc tacaagaaga
    29521 ccgttgataa agataacaac aaatgcaaca acaaatcccg gaaccaaagc ggtaaatcca
    29581 cgagaaactc cttctggaac agcttcaggc attttaataa cccaattatg tttaacacac
    29641 atacgataaa taataacagt cacaattgcc ataatgattg cggtaaaaat ccctgttgtc
    29701 ccaaaacgtg cgactccatt tcccattgcc catccatctg caattactgc accttctttt
    29761 agacttgtca cagtcttcat cattccacca tcaaaaatga tttgcggtac tgtcatgaca
    29821 aaagccatca aggcaagcaa ggcaccatta agaggattca tattgagttc ttcttcctct
    29881 gcataaattt ttgtcaattc atatgcaagt gatagaacga aataaagaga tagagaaccc
    29941 atagtcgcat agtttgcaac catgtaaagt gatgtgaatt tatcaaatga agcagagaaa
    30001 atatctgcca caattggcca aaatgagaaa gcttgtggca aaatactgaa taccaaaaac
    30061 attgatccta caatagtaaa tggtacagca gccatacctg cagccgtgat agcacgcact
    30121 actttaaact gagcaagttt gcccattggt cccataacat ggttttcaag aaaaccaaac
    30181 aacccgtttt gttgatccat aaatagacct ccttaataaa acataataat ttttactttc
    30241 taaagactag tttcaaatac aaattatact agatcaggat tataaactaa gtgagttctt
    30301 ttccaattgg acaaattgtt gataagcctt atctgttcgt ttataaattt ttttaattct
    30361 tctaatgtct aacaaactca gaactaaacc taatagaaga actacaaaaa caaataaacg
    30421 tgctacttgg ttattttcaa aaatcggaaa aagattctta aaccaacttg tccaagttaa
    30481 aacaagtaat cctattgaaa taagcatttg tattctaaca aacattagtg ttattcccaa
    30541 cttttctttc ctatttccat agagtttaaa ttgttcaaca gttgctaaaa tagaaaatac
    30601 tatgagcata atggggaaaa taataatagg cgagggatta ataaactgat tcaaaagcca
    30661 ataaatattc ccaaaaaaga agagtgctat tgaataacgt agaagaagat atcgattaaa
    30721 aaaagtatta gttagagcca tctctcgacg ttgttgttca atcttttgtc gttctttttt
    30781 atccatatca tttcctcctt atataacaac acatatttag ttaactttct tataaagagc
    30841 taacatttcc tttgctactt ctaataatgt catagtggtc attaaatgat cttgagcatg
    30901 taccatgata atttcaattt taatttccac tccacttgcg tattcttgca agagtttggt
    30961 ttgtgcatga tgcgcttcaa gaattatctc atttgattga tttaatttac tttctgcatc
    31021 atcaaaacta ccttctctca tttttgcaaa tgcttcatgt atttctgacc ttgcatttcc
    31081 cgaatgcagg ataatttcaa atgctgcaac ctgcagttcc tcttgattca tatgaacctc
    31141 ctattttatc ttctcaaata tgttaataaa atcttcaaag ttattgcaag atattagctg
    31201 attttgcaat tcatcattct ctgtcagaga gactatcttt ttagtcacag ttgccaaacc
    31261 ttcgttccca tatattgatg gagatagaag aaatactagc tggacatgtg aactttgatt
    31321 atcccagagt aacgaatctt tacaaattgc aaccgaaacc tttccctctg taccaaaggg
    31381 ctgaatagga tgcggaactg caattttttc agaaaaaaca actgaactta attcttcgcg
    31441 ctgtttaatt ccataaagta aagattgttc aaactcattt gattcaccaa cagataaact
    31501 ctcaaccatc ttttcaagta aatttacctt gtctgattca gtacatatta aaaagttttc
    31561 tttactaaaa tactgtctaa agccgttgtt ttcaaatttg ttaatctttg atgattgtac
    31621 ataactagaa acttgcatct gatccatagc ttttctaatc atttccatct catcactctt
    31681 aagaaacaca ctaactttaa aaactgggat ttgaaaatat agatttgata aatcaacagc
    31741 tgacactata aaatctattc ctttaagttt ttcttgattc aattcataat agcctattac
    31801 atcaacaact tctactcgct tcccaaactc cgtttccaaa cgatttctta acatttgggc
    31861 tgcaccaaat cctgttgcac aaatagcaag aatattaaac ttagtactct ctttgctacg
    31921 ttccatagca gctaaaaagt gaagacttac atatgctact tcatcatctg atattgtcca
    31981 ctccaagaac ttgtccatat ttgcaagaat ttctctagtc ataaagaata tatcactata
    32041 attctgttta atttcatcta ccaaagggtt atttaaggta atccggcttt ctaaacgtac
    32101 ttgtagtgtc attagatgag ttatcaatcc ttcaattagt tggaaatctg aagaaaagtt
//
LOCUS       DAVKUR010000021        32102 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKUR010000021 DAVKUR010000000
VERSION     DAVKUR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.021"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            486..605
                     /locus_tag="VW749_001075"
     CDS             486..605
                     /locus_tag="VW749_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0175121.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VW749_001076"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VW749_001076"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0175122.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPAIDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VW749_001077"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VW749_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0175123.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="VW749_001078"
     CDS             complement(2517..3044)
                     /locus_tag="VW749_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0175124.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRVRLFLEKKEK"
     gene            complement(3180..4376)
                     /locus_tag="VW749_001079"
     CDS             complement(3180..4376)
                     /locus_tag="VW749_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0175125.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9445)
                     /locus_tag="VW749_001080"
     CDS             complement(4466..9445)
                     /locus_tag="VW749_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0175126.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            9738..11369
                     /locus_tag="VW749_001081"
     CDS             9738..11369
                     /locus_tag="VW749_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0175127.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11910..13517)
                     /locus_tag="VW749_001082"
     CDS             complement(11910..13517)
                     /locus_tag="VW749_001082"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0175128.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENRN"
     gene            complement(13907..14494)
                     /locus_tag="VW749_001083"
     CDS             complement(13907..14494)
                     /locus_tag="VW749_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0175129.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14622..15071)
                     /locus_tag="VW749_001084"
     CDS             complement(14622..15071)
                     /locus_tag="VW749_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175130.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15076..15465)
                     /locus_tag="VW749_001085"
     CDS             complement(15076..15465)
                     /locus_tag="VW749_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0175131.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15493..16119)
                     /locus_tag="VW749_001086"
     CDS             complement(15493..16119)
                     /locus_tag="VW749_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0175132.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16133..16696)
                     /locus_tag="VW749_001087"
     CDS             complement(16133..16696)
                     /locus_tag="VW749_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0175133.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16861..17010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17070..17573)
                     /locus_tag="VW749_001088"
     CDS             complement(17070..17573)
                     /locus_tag="VW749_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0175134.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17766..18596)
                     /locus_tag="VW749_001089"
     CDS             complement(17766..18596)
                     /locus_tag="VW749_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0175135.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18581..20263)
                     /locus_tag="VW749_001090"
     CDS             complement(18581..20263)
                     /locus_tag="VW749_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175136.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
     gene            complement(20365..20622)
                     /locus_tag="VW749_001091"
     CDS             complement(20365..20622)
                     /locus_tag="VW749_001091"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175137.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(20629..21177)
                     /locus_tag="VW749_001092"
     CDS             complement(20629..21177)
                     /locus_tag="VW749_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0175138.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21192..22040)
                     /locus_tag="VW749_001093"
     CDS             complement(21192..22040)
                     /locus_tag="VW749_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0175139.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22228..23577
                     /gene="trkA"
                     /locus_tag="VW749_001094"
     CDS             22228..23577
                     /gene="trkA"
                     /locus_tag="VW749_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0175140.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23581..25020
                     /locus_tag="VW749_001095"
     CDS             23581..25020
                     /locus_tag="VW749_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0175141.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKIKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25145..26824)
                     /locus_tag="VW749_001096"
     CDS             complement(25145..26824)
                     /locus_tag="VW749_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0175142.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(26893..28305)
                     /gene="lacG"
                     /locus_tag="VW749_001097"
     CDS             complement(26893..28305)
                     /gene="lacG"
                     /locus_tag="VW749_001097"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0175143.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVQYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(28315..28659)
                     /locus_tag="VW749_001098"
     CDS             complement(28315..28659)
                     /locus_tag="VW749_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0175144.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(28827..30713)
                     /locus_tag="VW749_001099"
     CDS             complement(28827..30713)
                     /locus_tag="VW749_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0175145.1"
                     /translation="MVIRVFDQQKNTYSSFALEELRYYMNQVFNTDIELVEEKEADIF
                     VGLVNEEDGKDHIFISLNKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFIP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYKDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(30715..32037)
                     /locus_tag="VW749_001100"
     CDS             complement(30715..32037)
                     /locus_tag="VW749_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0175146.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRIFIQRGITIKMPNGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
BASE COUNT         9567 a         7069 c         5675 g         9791 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 aacctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttggcaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattag tttctagaaa tttttagcag atgtagtgta
      361 ccattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttaattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtgtagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aatgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatggcagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 agccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagt ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtatagaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaaa accttatcta
     1921 actgttcatc tatagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattgataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaaca cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaacgt ttctgataca cgcacaaaca cgtacgaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcagggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagaccg aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagtcgg ttgataagta ggttttggaa
     4921 ggactttgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtgt ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 tcaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcgt aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgtaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgaa cctcacctgt taagcgatca agctctgtct
     5521 tttcttccgt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaag gcttctttta cttctgatga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tttgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagctaa cttcatggcc ttggtaatga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcgtct tggccagtga cagtcactga caaattagca tttaccggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcga
     6421 gcggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttacc acggacttcc ttagctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttagtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gctcctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttca gtcttaggga
     6961 aagtactatc aataactgtt gcacctggaa cgatattttc agctagtggt tttggtaggc
     7021 tggtatcttt tacagtcata ccccaatcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc taggttaaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cccgctagtg
     7441 agctaagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctggagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgatct gtcttaccag ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttggcca gtggggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcatac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata ctttgccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaattg gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcgtcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttctgct gctggtttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacttgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgcagtt tcagtagttg cagcttcatt gcttgctggc gaagcagttt
     9181 cagatgctat cgctactcct tctgcctttt ctagcttgtt ttctctagca tgttcccctt
     9241 cattctgctt atcagcttca ttggtcgaat gctcactctc tcctgaaaca agctctgtat
     9301 tagctccgct attttcagga actgcagttt cttcagccaa ggctggacca gcaaataaaa
     9361 cagcaccaat catcagcgag caggctccta ctgataactt acgaatactg taacgacaac
     9421 gtctttcaaa aaatggattc ttcattttct cctcctaaaa gattgatttt gttgttttca
     9481 agaaagcgct ttatattctg tagtttttta tcaaactcta gaaccatgat aatcacattt
     9541 ttatcctaaa acatttttag acaaaaaaca atagctgctt tcataaatct aaaataaggt
     9601 taaaaactct taaaaataat acacttatca attataattt tcttttacaa acttgacgtt
     9661 aacacttgtt agatttactt ttatccttta aaatagaata ggagatattc cgcgattatt
     9721 tttcggagga aaaagaaatg tccattaatt ggcaggaaat tttatttcac tttttaggtg
     9781 gtctggggct attcttatat agcatcaaga ccatgggaga cggtttgcaa caagctgctg
     9841 gagatcgcct tcgtttttac attgacaaat atactagtaa tcctttcttt ggagttctgg
     9901 ttggtattgg gatgactgct ctaattcagt ctagttctgg tgtaacagtt attacagtcg
     9961 gcctggtcag tgccggtctc ttaaccttac gtcaggctat cgggattgtc atgggtgcta
    10021 atattgggac aactgtcaca tcctttctca tcggttttaa attaggtaac tatgccctac
    10081 ctatgctctt tatcggtgcc gtctgtctct tttttacgaa aaatcggaca gtcaataata
    10141 tcggacgcat cctctttggt atcggtggta tcttttttgc cctcaatctc atgagcggcg
    10201 caatggctcc actcaaggat ttacaggtct ttaaggacta tatgattgag ctaagtaaga
    10261 atcctgtttt gggtgtcttt gtcggtactg gcttgacctt gctaattcaa gcttcttcgg
    10321 ctaccattgg gattttacaa aacctctacg ccggcaatct aattgaccta cagggagctt
    10381 tgccagttct atttggtgac aatatcggga caaccattac agccatcatt gcctctttag
    10441 gggctaatat tgcagctaaa cgggtagcag gagctcatgt tgccttcaac attatcggaa
    10501 cagtcgtctg cgttattttt ctagttcctt ttactgtcct gattcattgg tttgaagcta
    10561 cgctaaatct agcaccggaa atgaccatcg cctttgctca cggaaccttt aatattacca
    10621 acaccattgt ccaatttcca tttatcggag ctctggctta ctttgtaacc aagattattc
    10681 ctggagagga cgaggttgtc aaatacgaac ccttatatct tgatgaacat ttcatcaaac
    10741 aggccccatc tatcgctcta ggaaatgcta agaaagagct cttgcactta ggaaactacg
    10801 ctgctaaagc ctttgacctt tcctataagt acatcattga cttggatgaa aaagttgctg
    10861 aaaaagggca taaaaccgaa gaagcaatta acaccatcga tgagcaatta acacgttatc
    10921 tcattgccct ttcaagcgaa gctctcagcc aaaaagaaag tgaagtgctt accaatatcc
    10981 ttgattcctc ccgtgatttg gaacggattg gagaccacac ggaggctcta ctcaatctga
    11041 ctgactatct tcaacggaaa aatgttgaat tttctgatgc cgccttgaaa gaattagagg
    11101 aagtttaccg ccaaactagt gactttatca aagatgctct ggatagtgtg gaaaacaatg
    11161 atattgaaaa agcacgcagt cttgtagaac gtcatgaagc aatcaataag atagaacgtg
    11221 ttctcagaaa aacccacatc aaacgcctca acaaaggcga atgttcaaca caagctgggg
    11281 tcaactttat cgacatcatc tcacactaca ctcgtgtatc agaccacgct atgaaccttg
    11341 ctgaaaaggt ttttgcagaa caaatctaat aaccaagaag ctatccatca taattggatg
    11401 gcttcttact ttttcctaag caagactagg ctgaatgaaa ctgaaagagt attctgcaga
    11461 tatatagtat attgaaacta gaatagtaca cctctatttc taaaacattg ttagaaatcg
    11521 atttgtcctg ttattatttc attttactat aatggattaa attaaaaaag tatagtgtat
    11581 tgaatctata acagtccatc ttgactgcta aaatatttct ataaattaat ttgacttttc
    11641 tgatagagat gttcacatct tatttcaatt catgatacaa tccagttcct aaaactttgc
    11701 tagaaattaa tttggctttc cgaattaatt tgttcagatt ttatttcatt tcaatatact
    11761 gataaatcca ttcactagca cagggcaaga gggagtcgct attgatttca acggtagcag
    11821 gtacatacag aggactccta cctcagatat actgcaatat catcgtgtgc aaaaaacctc
    11881 tgagattttt ctcaaaggtt ctgattttgc taatttctgt tctcaaccgc tgcagtaaca
    11941 aaggcagtgt agagttcttc tggtcggttt ggacggcttg acagttcagg gtgatactga
    12001 caagctacaa agaatttatt ttcaggaatt tccacgattt ctaccaaacg attgtctgga
    12061 gaaactcctg aaaagacaaa gcctgctgcc tcaaactgct cacggaaggc gttattaaac
    12121 tcataacggt gacggtgacg gcgttgcacc acttcttgat tgtgataagc agcagcagcc
    12181 ttagagccac gtttcaactt agacggataa agtcccaaac gaagggttcc acccatatcc
    12241 tcaatatcaa tctgatcacg catgatatca atgatagggt attttgtttc tggtgcaagc
    12301 tctgcagaat tggcaccttc aagacctaaa acgtgacgag caaactcgat acatgtcaac
    12361 tgcattccca agcagactcc caacattgga acatcatttt cacgcgcata gcggatggct
    12421 tggattttcc cttctgtacc acgttgacca aaaccacctg gtacgatgat cccgtctgca
    12481 tcagacaaga gttctgctac attctctgct gtcacatcat tggcattgac ccaattgatt
    12541 ttaacttctg catcattgac atagccagag tgtttcaagg cttcgaccac tgagatatag
    12601 gcatcttgca actccacata cttaccaaca agggaaatct taacttgttt cttgaggttc
    12661 atgaccttgt ccaccatggc tgaccattct gtcatatccg ctgctggtgc gtctaatttc
    12721 aaatgatcac aaacaatttg gtccatccct tgtgcctgca agttcagtgg aatttggtaa
    12781 agatgttcaa catccaacga ttcgataacg gcttctggtg ccacatcaca gaactgggcc
    12841 agtttatttt taattccttg accagctggc tcttctgtac gaataaccaa catatttggt
    12901 tggattccca agccacgcaa ttctttgaca gagtgttggg ttggtttggt tttcatttca
    12961 ccagcagcct tgaggtaagg aagcaaggtt gtatggatat acatgacatt atccgcaccc
    13021 acatctgcct tcatctgacg aagagcctct aggaatggca aggactcgat atctcctact
    13081 gttccaccaa cctctgtgat aatgacatca gagtcggtcg ttagagcggc acgcttgatt
    13141 ttttctttca aagcatctgt gatatgagga atgacttgaa cagttgcccc aaggtattct
    13201 ccacggcgtt ctttacgaag aacttcactg taaattttcc cagttgtcac gttggaatat
    13261 ttgttgagat tgatatcgat aaaacgttca tagtgaccca agtccaaatc tgtctcagct
    13321 ccgtcatctg tcacaaaaac ttccccgtgc tggtaaggac tcatggttcc cggatcaata
    13381 ttgatataag ggtcaaactt ttgaatggtt actttgagac cacgattttt caagagacgg
    13441 cctagactcg ctgccacaat ccctttccca atggacgata ccacaccacc agttacaaaa
    13501 atatatttcg tagacataga ttcctctttc taaaatgctc aaggtcttgt taactacgag
    13561 gggatataga aaacaagacc ctactaataa gaataatctg ggacgactgc accagattca
    13621 caactaatac tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtagatatg
    13681 tgttcctgac tttgtcagtc ttatctacaa cctcaaaaca gtgttttgag cagcctacgg
    13741 ctagtttcct agcttgctct ttgattttca ttgagtataa aatacaagaa gataacttct
    13801 tgaaaaaaca aaaatagctc cctaagaact agggagcccc gacctctaaa agaggtgccc
    13861 aaacaatatg atacctaaaa ataggataat tgtcaatagc taactcttat tcctcgctgg
    13921 tttcagcgtc gtcatctgaa aactcgtcgt cgtcttcgtt gagatccaca tcttctccca
    13981 agtcatctgg agcgatttcg ttgatttctg catcataagc ttccacttca tttttttcat
    14041 catctggatt ttcatcatcg tatgaaagag ctggatctgc ttcgtatgca tcttcgtctt
    14101 ctggatcatc tgcattgtag tcaatggcat ctgaatcacc atccataaag gcattgacac
    14161 gttttttctt agcttttggt gctacttcat cgtcgtcatt ttcttcaaga gcgatgattt
    14221 cttcgtcgat ttcgtccaca ccataccatg aacgaagacc ccatttgttg tccccaagtg
    14281 agatgaagct accgtcaaag ttcaactctg tgtagaacaa aggcaaagct tcgcggatat
    14341 cgctgtttga tgttccaagg tagttttgaa tttcgtttac aagatcgcta aaatgcatct
    14401 catgatcgcg accacgaagt tccaagatag cacgcgctac ctcaatcata gatagttcac
    14461 ttttttcttg cccagcaaat acttctaatt ccaaagcgtt tctcctcatt tatactacta
    14521 tcgccagagc gaacagactc tgacctcatt ttatcattta ctctttattt tacgataatt
    14581 ttgcggaata gtcaaaggtt aagggggaga aagtggcagg attagactaa ttccaatata
    14641 aaactccttc ctttttctgt tgctccattt tccacaaatc caagcgactt gaaacacctc
    14701 ctagaagcat gattgtaggt gtagatttcc ttgactctca attctttcca tccttttact
    14761 cgagccaatt caatcaaagc acttagaatc ttttttccaa gtcctcgatg ttggtaagcg
    14821 gaattcccaa tcacaatggg gagattatcc tgagatagtg taatatcccc aattggaaac
    14881 cattctccct tctccttgac ttcaatccaa aaaagctcac catgccgatc caaataggaa
    14941 tacatggctt ccaaggtcgc ttgactgtaa ggaagcttca ccccatctac gaggtaaacc
    15001 aagttcacat cctgatacca agcaaaagct tcctcacaat gattgacctt ataataagga
    15061 acaaaacaca atgcactacc ttttcaacaa aagagttgct gcttgattaa aaccatcaca
    15121 ccagttatac cattttgctt catacccatc ttgagctagg atacgatctt ctaaatcaaa
    15181 aacagagtaa atctttcttt cctcgcaagc ttgcgcatag agatgatata gttcatcacc
    15241 accatctcta tcccactcag cagaaatcgt atcccgacct gccaataaag cctgataagc
    15301 cctgtgatgc ccatctgtaa tcagcaaaca atctccaaag gcaagaatac tgattggatc
    15361 gacttggttt gtttctgccg actggtaaag catctgaata tcttgcaact tcttttctga
    15421 taaatatagt tgagtcggat gaagatctgc tatattgact ttcatttctt tctcctcaag
    15481 ggaattcgat actcacttct gtttgccttt aaatcgccat tggaagcgga gcttgtcata
    15541 gaagggaaac tcgataaaca ggactcccaa gcccacacag agactggcaa agacgtctga
    15601 tgggtaatga acccccagat agactcttga taccagcaca ctgactaggt agaggccaag
    15661 gacgatttgt acgatttttc tccagactgg atttttaatt cgttgactga gaatgacaat
    15721 cagagtacct accatcaaag ttacagccag agaatgtcca cttgggaagg aaaatccctt
    15781 ctcttccacc agatgtaaga tagctggtcg tgggcgctgg tagatatttt taaaggtcac
    15841 gattaaaaga cctgccaaag ccagatttcc cagcatgaag aaactttcta tcttccatcg
    15901 cttacgataa aagacaaaag ctgtaatgac aacccaagtg ataatcactg ggatatcaat
    15961 cagacgtgtg agggctcgaa aaagaatagt caaataatct ggtaagtctc ctcgaatggc
    16021 agtctgaatc gattggtcaa aattgaccaa catttcaggg taaaatttga ccatatagcc
    16081 aagaataacg aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt gtttatcttt
    16141 catagtgttt taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga
    16201 ttacaccctc aatcaagtta aaaggtaata ccatggtcat taggtagttg gaaagtccca
    16261 aaatttttcc aatatcaaag ttagcaaact tagcgtacaa aggaacagca taaacatagt
    16321 tgagaaccaa catggccaag gttaaaccaa cagttccagc tagagagcct agtaggaaac
    16381 gaagggttgt ccgttccttt ttccaaatca aagcaaatac gatgacaaaa actcccaaag
    16441 ctacgatatt catcggcaaa ccaatgtaag tattcactcc ttggctgtta agaagcaatt
    16501 tcaatagtga gcgaagcaag agcactccta gagcagcagg caaatccatg accaccagac
    16561 ccacaaggac tggcaagata ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg
    16621 gaaagtcaaa gtacatcagc acaaatgaga tggctgataa aattgcaatg gtcgaaagtc
    16681 gacgtgtgtt tgtcataaca ggttcctcca attttctata aaatcagaag aagttggaaa
    16741 ggattcctct atctattctc actttttata tcccaaaaat tccctcttac tctattaaag
    16801 aaaaacaaag caagtggtta caatccggct ataaatctat caaaacagac aaagctattc
    16861 tttcgtcttc tcccatccag actatactgt cggttgtgga atctcaccac atcagcttgc
    16921 gctcgcggac ttctttaaag agaaggaaaa gatcatttcc tagttaaagt caccgccggt
    16981 cgggaatcac accctgccct gaagactctt ttatcataac aaaaaacgct tgcaagcgca
    17041 agcattttgt tcattttcat tttcattttt tatttcaatt tatccacttc ataggtatgg
    17101 acgagctcaa gacctgcaaa gttctgctgg cgaagagcct catagacaat catgcagacg
    17161 gtattagaca cattgagact gcggacatgt tcatcattca tgggaatacg gagagccttc
    17221 tcaggatgtt ctcgcataaa atcttcaggt aagcccttgt cttcacgtcc aaagagaaaa
    17281 taatggtcct cgtcagtcga taaatccacc tcagaataga ctttttctgc gaatttcgaa
    17341 atcagataga gttttccctt catctgagat atgaaatctt ccaaactctc gtaaaaataa
    17401 atctctagct tatcccagta atccaatcca gcccgcttca tcttgcggtc atcaatagga
    17461 aagcccatag gcttgatgat gtggagggga gaattggtcg cagcgcaagt acgcgcgata
    17521 ttgcctgtat tttgtggaat ttgaggttca aataatacaa tgtgatttgt catgacttgc
    17581 ttcctttcac cattgcaaaa aaatagccac actgcccgga gtcaagctca gcaaacagcg
    17641 tggttaaggc atcgttaact tacctcacaa caggtttgaa gtaaatcagc gaaactactt
    17701 tcttagtata acactttcag aatcattgtc aatagaaatg acttgatttt ttcaattttt
    17761 tcaagctatt tccaagggtt gtaaaatcgt ccctgattct gcaagataag tagtaaacta
    17821 actactaaaa acaaggttgc caagagcaag gtaatatagt ctcctttttt caaggcctga
    17881 taactatacc atgtgcgttt tttctctttc ccaaagcggc gaagctccat ggcagtcgca
    17941 atggtatcaa tgcgttctag cgagctaaaa atcaagggag taataatgag cagattgcct
    18001 ttgattcgtt gcataagaga agctttcttg gataattcca tcccacgcgc ttcctgagac
    18061 atcttgatgg taaagaattc ttcctgcaaa tctggaatat agcgcaaggt tagactgaca
    18121 gaataggcaa tcttgtaagg cacaccaatt tgatttaaac tggaagcaaa ctgactaggg
    18181 tgggttgtca tcaaaaagat aatagccaga ggaatagtgc aaaggtactt aatagccaaa
    18241 tttagcagat aaaagagctc ttgactggtc agagtgtagg caccgattcc ctgccaaatc
    18301 acacttctct ctccgtaaag tccaacccca tactcgggag aaaagagata gaccatcaaa
    18361 acgtttaaaa cggcaaatac cgtcgcaaaa acggctacaa aggaaacatc tttaaaatgg
    18421 atttctgaca aatagaggag aaagaccgaa aagatggcaa tcagaacaag cagtctggta
    18481 tcatagctaa tcatggccgc caatgacacg agaatgaaaa agaggagttt cccagcgcct
    18541 gacaagcgat gaatcacagt atctctatgc tggtaaccga ttaatttagc ttgcatcctt
    18601 ctctcctttc tttgtaaaat gccgttaaag caagtggatc cacgtcgagt ttcttagcca
    18661 agttgaagat agaagtctct tttaggttgg cttttactaa cagctcagga ttgctcaaca
    18721 gactagctgg atcagtatca gcaatcaatt ccccatccac catgacaagg gctcgatctg
    18781 aataatccag catcaattgc atatcatggg taatcatgac aatggtatgc ccttgttgat
    18841 gcagttcttc gagaaattcc ataatctcag tatagttctt ctggtcttga cccgcagtcg
    18901 gttcatctag gaggataatt tcagcgccta agaccaaaat tgaggcaata gtcacacgtt
    18961 ttttctgacc aaatgacagg gcagaaatgg gccaattacg gaattcatag agaccacaga
    19021 ttttcaaggt ttcatagact ctcgtttcaa tttcctgctc gtccacacct cgcaaacgga
    19081 gtcccagagc cacctcatca aaaatcatat tggttgaaat catttgattg ggattttgca
    19141 gcacatagcc tactcgttcc gcccgctctg caacagaatc tccttttata tcctgtcctt
    19201 cccaaagata gcggccttca gtctggataa agctactcaa ggccttggct agagttgact
    19261 tccctgctcc attttttccg acaatggcaa tcttttcacc ctttttaata tctaaatgaa
    19321 gagattttaa aatcggtcta tcatcataag aaaacgacac gtcctctagt ctaaagagtg
    19381 actgcaattc tggggtttct tttaccagtt ccgtccgcaa ctgaacctga ccttttgaga
    19441 tagacaagtt atccagatct gctaattgtt cttccttgac taaatccaca cccaattgac
    19501 ggagagtggt gagataaagg ggttcgcgaa ttccattttg ggtcaacaaa tcagtcgcca
    19561 gtaactggtc agggctccca ttaaaaagga tacgaccatc gtttatcaag acaatccgat
    19621 ccacagggca atgcagaaca tcctccaaac ggtgctcgat aataagggtc gtcgtcccct
    19681 cctccttatg aatctggtca atcaattcga taatatcctg acctgacttg ggatcaagat
    19741 tggcgagtgg ctcatcaaac aagagaatcg gactttcatc aatcaagaca ccagccagac
    19801 tgactcgctg cttttgtcca cctgacaaat cctgagggcg ctgatccagt aaaggaagaa
    19861 ggtccagctt ttcagcccat ttataaacac gacctttcat ctcatctagg gctgtcacat
    19921 cattttccag agcaaacgcc aaatcttctg ccacagacaa gccaataaac tgcccatctg
    19981 tatcctgcaa aactgtgcta accagatgag acttatcata gatgctcata tcaaaggctg
    20041 tttgaccctt tatcaaaaat tctccatatg tctgaccctt gtaaatattg ggaataatcc
    20101 cattcaaaca ctgacccaag gtagatttac ctgatccaga tggtccaaca attaagactt
    20161 tctctccctt gtaaatggtc aagtctatcc cttgcaaggt cggttcttgt tgtgtttcat
    20221 accggaaaga gaaatccttc cactcaatta tagcttcttt catcttactc tcttcattcg
    20281 cttcttagac ttctatttta tcataaatca agcccttctt gcagtctctt ctcttaaaat
    20341 cttagcgcca aaaagattcc tatcctagct tacttgccta actaatctat aaacatcgaa
    20401 aaagactagt tgcccagcct tccccatcat tttatactct tcgaaaatct cttcaaacca
    20461 cgtcagcttc gccttgccgt aggtatggtt actgacttcg tcagtttcat ctacaacctc
    20521 aaaaccatgt tttgagctga cttcgtcagt tctatccaca atttcaaaac actgttttga
    20581 gcaacctgcg gctaacttcc tagtttgctc tttgattttc attgagtatt agtccttttt
    20641 caaacttcct gcacgagttt gggttcctgc ataggcaagt aagagaagag ttcctgcaat
    20701 agctacagat acaccattgg caattcccgc aacaatccct tgtgcaaata ctttttctgc
    20761 cgcttcttga taaatcacaa catctccaag tggtgccaag acaccccaaa caagggcatt
    20821 tgcaagtagt tgaatgaggt taaaaataag aatatctttc cagtcaaaaa caccattgat
    20881 cacgcgaacg tactttctaa aaagtcccac aactaaacca aagagtccgc tagcgataat
    20941 ccaagtccac catagaccat aaccagcaag agagtccttg attgcatgac caatcaaccc
    21001 gacaagcaaa ccgataatcg gtccaaaaat aatagaaagt agcgcttgta ccgcatactg
    21061 aagctggatg cttgtatttg gaacaggggt tggaatgttg atcatcccga tgacgacaaa
    21121 gagggcagcg ccaattccga cagcaacaac ttgtttaatt gtaaatttaa tttccatact
    21181 attctcctat tttatccttc tattttcttt atttcaatgg tccaagatga accgacacct
    21241 acattatagg ccttggcaaa ggaaccttgg ttgatagcca aacctaaacg atagagagag
    21301 ttgatgtaaa ggatgggttg cccaattctc acatctgcaa atgatttgcc atagacaacc
    21361 tgattttgat agaccagcat atcagcatga tagatggtca cttcaaaacg atcaccaaat
    21421 tctggttcca gcttgtaaaa ttcttcccgt gtgatagagg tccaaagcga accgaaacgc
    21481 acatccagaa tatcaatggc tcccttcacc agatgatctt ctatgatggt cgctacgact
    21541 ggaagctcta caatctgttc cacactgagc tctggcccta cttcctcaaa agtaatgtga
    21601 ccactggcca gtttagcacc agtataggca tagacatcac gaccgtggaa ggtataagaa
    21661 tgctctgtgt tttgacgcct attggccacc tcagaaatct cacgaatggc tacaatgcca
    21721 acgtgtttct tgataaagga aagcgtccca ttatctggcg tgacaatgta ttgatttttt
    21781 gcagtcttgg caactacact cttacgtttc gaaccgacac ctggatcgac aaccgataca
    21841 aacgtcgttc cctcaggcca gtaatccacc gtctgaaaga gacgatagct cccctcaaaa
    21901 atattataag gcgtgatatc gtgcgtcaag tgatggattt ttaaggttgg agactcttct
    21961 aaagccactc caatcatagc cgataccgca ccatcaacca gaccaaagtc tgattgtaat
    22021 accagtaaat tattattcat tttatctcct tgtatatcct ttatcatacc atatttcaga
    22081 gaaagtcgct aatagctatt tcaattggtt agggtatagt tttaccttat agcgaatttt
    22141 cactaaaagc tcttgttatt agctagtagg tgcatttttt cttgaaaaag ggtatgatag
    22201 ttacatcatg aaaaagtagg ttttattatg aaaattatcc ttgtcggagg gggaaaagtt
    22261 ggttttgccc tctgtcgctc cttggttgca gaaaagcatg atgttttgct gattgagcaa
    22321 gacgaagctg ttctcaatca tattgtcagt cgctttgata tcattggtat ccttggtaac
    22381 ggggccgatt ttgccattct tgagcaagcc agcgtccaag attgtgatat ctttatcgcc
    22441 ctgactgagc acgatgaagt caacatgatt gcagcagttc tagccaagaa aatgggagct
    22501 aaagaaacta tcgttcgggt gcggaaccct gaatattcta actcttattt caaggaaaag
    22561 aatattctcg gtttttctct tatcgttaat cctgagctct tggctgcccg tgctatcgcg
    22621 aatatcattg acttccccaa cgccctgtct gtcgaacgct ttgctggtgg acgcgttagc
    22681 ctcatggaat ttgtcgtcaa gtccaccagc ggtctttgcc aaatgcccat ttctgatttt
    22741 cgtaaaaaat ttggtaatgt cattgtctgt gcgatagaga gggatcatca aattatcatt
    22801 ccaagcggtg acatgactgt acaggataaa gatagaatct ttgtcactgg taaccgtgtc
    22861 gatatgatac tcttccataa ttattttaaa tcacgcgccg tgaagagcct tctcatcgtt
    22921 ggggcaggta gaattgccta ttatctactt ggtattctca aagatagtcg tatcgataca
    22981 aaagtcattg aaatcaatcc tgaaatcgcc agcttcttta gcgagaaatt cccaaatctc
    23041 tacatcgttc aaggagatgg aaccgcaaaa gatatcctgc tggaagaaag tgctcaacac
    23101 tatgatgccg ttgcgactct aacaggagtc gatgaggaaa atctgattac atctatgttc
    23161 cttgacaggg taggtgtaca gaaaaatatt actaaggtca atcgtaccag tctcctcgag
    23221 attatcaatg cgcctgattt ttcaagtatc atcacaccta aaagcatcgc tgtagatacg
    23281 attatgcact ttattcgtgg tcgagttaat gcccagtatt cagaccttca agccatgcac
    23341 catctagcca atggccaaat tgaaaccctg caattccata tcaaggaagc caataaaatg
    23401 actgccaaac ctctttctca actgaaattg aaaaaagggg ttcttattgc agccattatt
    23461 cgaaagggca agactatttt cccaactggg gaggatatgt tggaagttgg agacaagctc
    23521 ctagtaacaa ccttgttgcc aaacatcacc aagatttatg acttgattgc gaggtaagaa
    23581 atgaataaaa gtatgattcg ttacctcctt tcaaagttac ttttgattga agctgttctc
    23641 ctcttggttc ctgtggctat cgctgtctat taccgtgaat cgagccaagt ctttacagcc
    23701 ctcttttcga ccatagggat tctcgtattg ttaggcggtt cagggagttt acagaagcca
    23761 aaaaatcaac ggatttatgc caaggaggga gtcttgatcg ttgccctctg ttggatcctt
    23821 tggtctttct ttggtggtct cccctttgtc ttttctgggc aaatccccag ccttattgat
    23881 gccttttttg agattagttc cggctttacg actactggag caagtatttt gaacgacgtt
    23941 tcagttctca gtcgttccct cctcttctgg cgaagtttta cccacttgat tggagggatg
    24001 ggagtgcttg tttttgcact tgctattatg gacaatgcca aaaatagcca cctagaggtg
    24061 atgaaggctg aggttccagg tcctgttttt ggcaaggttg tatccaaaat aaaaaacact
    24121 gcccagattc tctatctcct ttatctagct ctcttctccc tctttgtcat catctattat
    24181 ctagctggta tgcctctcta cgatagtttt gtcattgcta tggggacagc gggaactgga
    24241 ggctttaccg tctataacga tggaattgcc cactatggta gctcactgat tacctatctg
    24301 gttagtatag gagttttggt ttttggggta aatttcaatc tctactacta ccttatgctc
    24361 cgtcgggtta aggccttctt tggagatgaa gagcttcggg cttacttggt catcgtgctg
    24421 gtttctacag gcttgattag cctcaatact ctctacctct acccaggatt ttccaaaagc
    24481 tttgaaatgg ccttcttcca ggtttccaac atcattacaa caactggttt tggatatgga
    24541 gatattacca actggcccct cttctcccag tttatcctcc tcttcctcat gacaatcggt
    24601 ggttctgctg gatcaactgc aggtggactc aagattattc gaggcctcat cctttcaaaa
    24661 attgccaaaa atcaaatttt gtccattcta tctccccacc gtgttttgac tctccatgtg
    24721 aataaaacgg tgattgataa ggatacccag cataaaattc tcaagtactt tgtcatctat
    24781 gctatgattt tgctatccct tatctttatt gtcagcctag atagcaatga ttttctgatc
    24841 gtgaccagcg ctgtctttag ctgtttcaat aatatcgggc ctattctagg aaccacttct
    24901 agtttctcaa tctttagtcc tatctcaaaa attctcctct cctttgcaat gattgcaggc
    24961 cgcttggaga tttacccaat cctccttctc tttatgaaga gaacttggtc taagagataa
    25021 aatacaaaat ccctcttttt acaattgtga aagagggatt tttatattaa aaagggggaa
    25081 cgtttttaaa tccaagcctg tctgtaagca aagtccttac tcaaataaaa gatggaaaaa
    25141 cttactacac agcttggtaa tgctccaata caaattgtaa ggctttactt ggattctttg
    25201 ttaaatgaat atattccatt cctctggtag caactatctg aatacctaat ctttctgcat
    25261 ccaccttcat ctctctataa taactccgaa cttgtggagc cagaataatt aaatcataaa
    25321 cacccataat atcataatga gctccgtacg ctcctgaatt cgcaatcact ctaacttctg
    25381 ctaattgagc gccctcgtta attgcattgg ctaattgcgc acttgttcca gaccctgcac
    25441 aaagaaccag tactttcaac tccttacttt ttatttcatc taactcacca ggcattattt
    25501 cacttgtctc ctcctctaaa ataatatcat ttgagcttgc aacatcttct ttcatcagta
    25561 actgtctatc atacgctcta cagaatggca aataaatcaa tatgtcgaca actaaaatca
    25621 aagataaaaa tacaaaggag atagattgaa aattcgttcc aattaacaat cccaagggac
    25681 caggaaaggc ccaaggtaac tggatataaa atccattcat tccaaagaaa tcaataaaga
    25741 cctttcctag aaatacattc actggtggag tcatcaaaaa aggtacaaaa agatagggat
    25801 tcaaaataac tggcatacca aatagaagag gttcattcac cgcaaataaa acaggagtaa
    25861 ttgtagcttt acctaccgat tttaattgtt tagaccgcat aaagaaaatc aaaataaatg
    25921 gtacaacaaa ggtagccccc gttcctccga tagcagcgat ataatttccg aaattaggcg
    25981 ttaaagaatg ataaggaaac tgcccatttg caagaagttg agcattctct tccatattgc
    26041 tcagttgtaa agctgtaaca gcaggtaaga caatagatgg tccatgaatt ccaacaaacc
    26101 aaagcaaagc gcacataaac caaatcaaca tcatagcagg atatgattct gcccccttaa
    26161 aaataggagt caatagttgt tgaaatactt gggcaaaagg aacatctaaa ctaaaccgag
    26221 atacaatatc taacaaacca ctaataagta aaacaaaaga aaaaggaaaa atatctctaa
    26281 aagcttgtga tatagcccca ggaacttcct taggtaaatg aatagtaatg tctcgcttaa
    26341 tacagaatcg gtaaacattt acagtaataa aggcactgac aaacgaagtt atcaatcctt
    26401 gagatcctaa atagtttgtc gacaaacttg tagatcccgt cttctcatca actacaagcg
    26461 ttacagttaa taccagataa ctacatatgg ctgccaacat tacagaagta tcatttatta
    26521 cctttccagg aggcattttt ctattaacat ttccagccaa tgactttgca actgtccctg
    26581 aaacaataac acccaaaact cccatggtta gcatatacac tttcctcatc caggcaatag
    26641 ctggactcgg taactctact ccgaaatttt taggaatcat aataataatc atcaaaaagc
    26701 ttgaaaacat aattaaaggc atagtagcaa tgaatccatc tttaatagcc atcatataat
    26761 tattagtaga aattttttca aatttccctt gttgcttttc aatggcagcg actagcttat
    26821 ccataaaact cctcctataa aaaattcaac ctcatattta aaacatatta aacatcattc
    26881 aaatcgctaa ccttaattcc gttttagccc ttttacccaa agagcacttt tcttaatata
    26941 tcgcttctgt gtctcataat caacaaagaa aagaccatat cgcttattgt agccattcgc
    27001 ccaagaaaat tgatcttgca aagaccatat aaaatatcct tgaatattga ctcccctatc
    27061 tcgagcctct aaaactttgt gtaaatgttg ctcaatataa cggattctct tactgtcatc
    27121 aataatatca ttctcgccct ctggcttaac ctctttaagg gctgtaccat tttcagttaa
    27181 ataaatgaca ggatgttgag gatattcttc tttgatacga agtaacatat caaataagcc
    27241 ttgaggataa atattccaat cccaatctgt tgtcggaata ccaggctttt ttacaaattc
    27301 acctagagca tttaatttaa aagaggactg tccttttatt cctgttgaat taaattcttg
    27361 tctattttca cctttgtatt cacgaataaa ttctgaacga taataattca tcccaaacat
    27421 cgtattaaga ggtgcagctc ttttcataat ttctaaatca ccatcttcaa taataaagct
    27481 agaattatta gcttccaata tttgatttaa gtgaaaaagc gtgtcatcac tgtagtagcc
    27541 caaaaaagtt ccatctaata gaaatttatt attataaaca tcataccgtt tagctgccaa
    27601 aatattttct ttttgcccat caataggata gcctggcttt aaagcatgaa tacaacctac
    27661 ctttccctca atccctaatt gatgaaattc gaggactgca agagcatgcg ccaacaacat
    27721 attatgattc gcttgaattg cttcagataa ttgaaaatga tgattcggag gaaactgacc
    27781 tcctatatat tgacctgcag caagagacat cagttcattg attgtaaacc aatgcttgac
    27841 ttctgtaaat tcttggaaac aaaagcgagc atatcgtatg aaacgatcaa tattctctct
    27901 attcaaccaa tcccctgttt ctaacatttt ctgaggcgaa tcaaaatgat gtaaagaaac
    27961 aaacggaatc acattatgtt ttaagcagga ctgaaagact ctatggtaat actgaacagc
    28021 caatatattc ggctccccat ctatatcagg aaatatgcga acccaagaaa tagataaacg
    28081 caaagcctgc aaaccatgtt ctgccgccaa ggctatatct tcttcgtaac gataataaaa
    28141 atcactagct ggatctggta agaacggact attttcttgc aaataaacat cccacatatt
    28201 tattcctttg ccatctaccc tagttgcacc ctctacttga taagcagcgg tagcagctcc
    28261 taataaaaac tccttcggta aggctttaac ctgtaaattt tccatgacta atcctcattg
    28321 caaaccaata tgttcttcaa tctttcgaat tcgttcatat tcatcaataa aaaactttac
    28381 ctgatcatac aatagcatcg ttgtcatcaa agtatcttga ccatgaatca tgataaaact
    28441 cacttcaaaa ttatctccag atgcctcctc cgctaataaa ttagtctgtt ctcgatgggc
    28501 agacactatt gagtcgtttg cagactcaac caattctctt gcctgttcaa aatatccatc
    28561 tctcgcaaac gccaaagcat ccatcaaatc tgaccttgca tctcctgcgt aagcgacaat
    28621 tgtaaaacca agcatattta tttcttcttt tgatttcatc tttcttcctc ctcaatcttg
    28681 atacatcttt tacacatcat tattaaaatg acttcgctac gatacaaata gaaagttgac
    28741 cctaaatatc ttaaaaatcc ttaaatttca taatatttag gatcaatctt ctctgaatac
    28801 cttagttcat tttctatact tataatttat aagtggaaac cagcgtaatt ttttgctact
    28861 tcaattacac gataaacatc caaattagat tggaatagca attcgtgacc acggatataa
    28921 ttcaaaacat ttctccattc atcttgagct tgccttgttt ttccagttgc ttgaagatat
    28981 aaagccttcg ccatcttaac aacatattca cgatgataac tgagctgttt ccattcatcc
    29041 ttttgactat ttaataactt agaaatattt tcctcaataa ttggtaaaaa attatcagct
    29101 agattgtaag ctatataata atgattcgct aaaacatcat tttgacggct gccaattgca
    29161 ttaaaataat cacatgagga ataactagat aatttttcta aatattcaac aacagactgc
    29221 caatttgacc catacaaagc agaaaagtat tcttcaatca attcttcata acttcttgtc
    29281 ttcttccaga gcatttgccc cataacataa ttaggaaaat tatgagggaa tccggcacgt
    29341 aattcttgac acgaaatgta cccgttcaaa tgtaggtttg aaagataaga tacatctttg
    29401 taaatagttt gactaatttt catatagcct aaatcgccat aatgagcacg ccctaaagga
    29461 tagtcatata cgaaactatc tcctttaaat gttttttgcc actcaaaaag ataagataaa
    29521 ttttcttcaa gagaattcgg aagtataatt ttattacgca gataaggttt aggcgtaggt
    29581 atggaattgt caaaatctac atctgcataa ctcatttcaa atgttcttgt aatcggtgca
    29641 aacatcatgg taaagcgttc aggattatct aatttttctt tctgaggcgc ccataacaac
    29701 tcatggtaaa gtaggaaaca aatctttgta tctaatccct cactcgttaa agccctatcc
    29761 aattgattga gaatacgaat atactgatcc gaaaccaatt cttgtctaca gttttcgcat
    29821 tcacaaatat tattacgagc atccgacaac catacatgta agtagttaac atcaggtctt
    29881 ttcttggcat aatccttaat aatttctacc atcttatcag ctacatctgg atttgaaaaa
    29941 tccaggctgg ttaaaatcgg agccgtatta aacaattctc gtttcccgtt tatttcagcg
    30001 acatagggtt tcttctcctc tgaaatacta agacctgatt cccagccaaa ttttgaagag
    30061 taacctaaaa cctcacctgt ccatccatga ccaacacgat gatgaataag acctcttttt
    30121 tgcaattctt tatccaacct atcactcaat tcttgtacta attcatttga gaatttttct
    30181 ttatttaggt atggattaaa ctcatgttca taccaacgtt tcaaaaaaga atagggattt
    30241 tcaaactgaa tgaaaaaact gttcatccca atcttaggta gccaatcaat gaaatctagt
    30301 atattttcaa atgaatctgc tccctctata catactcccc tatgatagta acttgctgtt
    30361 tcatctatag atagctcttt atctaaaaaa tcttcaaatc ttaactctgg aataaagtca
    30421 tgtccgcgcc ctggtctagt atacacaaca ccaaattcat gaaacattcg gtaaattcca
    30481 ataagtaaac ctacaattgt attggactca attctcccct tacctttgtt taatgagatg
    30541 aaaatatggt cttttccatc ctcttcattg actaatccta caaaaatatc cgcttccttc
    30601 tcctcgacaa gttctatatc ggtattaaat acctgattca tatagtatct taattcctct
    30661 aaggcaaagc tagaataagt atttttctgt tgatcaaata ctctgataac catcttattt
    30721 ccctccaaca gtagcttttt ctttttcaag attgcgttta tctgcaattt tgaagaatgg
    30781 ataataaatt gctacagaaa ccaaaatcaa aacaacttgt aatagagctc ctcgccaact
    30841 agcccctgtc gcaaggaagc ctcctatgat aggtggcatt gtccacggaa ggattacacc
    30901 tgttgtatag ggtactaagc ctacagccat tgatacatag gtaatcaagg cattgattgt
    30961 aggagtagca ataaacggaa tcagcataat aggatttaaa accgttggaa acgtaaatag
    31021 aatagctgta ttgatattaa agatagacgg tataatagct agcttaccta atgttttatt
    31081 agcacgactc ttactaaata ggaagagaca aatcgcaaga ccaatagtcg ctccaccgcc
    31141 accaataaat acaaataaat ctttaaacgg taatgtaata atgtgttgta gggtttgtcc
    31201 tgcagccaca gcttcttggt tttctgtagt aaattgtaac caaactgggt ctacaaaagc
    31261 atttaaaact tgtcccccat taactccaca gaaccaaaag aatgagttta caataacaca
    31321 taaaatcata cctggaagtg ttcctgcaat taacttaagc ggcgttccaa caattgcacc
    31381 taaaagtccg ttgagacctc ctgcaactcc tgctgcttcc agacctttta agaccaaagc
    31441 ccacaaaaca aaagtagtaa aaccaggtaa aagagctgaa aatgatttac tgaccacatc
    31501 tgggacacca tttggcattt ttatcgtaat tccgcgttgg ataaaaatac gataaatctc
    31561 cgctgtaacc aatccaatgg taatcgccat aaacaaagaa gacgcattca ggctagaaaa
    31621 tggtattgca cctccaaata actgcttgac ctgctcccca tttttatcat aaaccatact
    31681 tgaaaaacga ggggccatca atacaaaact ggataaggct atgatccctg cagacggacc
    31741 atctgtacca tatccttccg acaacctgta ggcaataccg aaacaagcga ccaaggagat
    31801 aatcgctact gttgactgat tcatagttgt caagatactt agcaatccaa cactattcag
    31861 ccaatttgta aaagcctctt gaggccaact gattagaata agaaataaag agccgactaa
    31921 aatcaaaggc attgccatca taaatccttc acgaatagct ttcaaatgcc gttgattgcc
    31981 aactttttca ccaaacggag cgactttcgt ttctaaaaac gttaaaatat tgttcatcac
    32041 cggaactcct ttttttattt tttataaatt aaatatacca ctaacagaaa gcgttgtcaa
    32101 ta
//
LOCUS       DAVKUR010000022        31716 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKUR010000022 DAVKUR010000000
VERSION     DAVKUR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.022"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..182)
                     /locus_tag="VW749_001101"
     CDS             complement(<1..182)
                     /locus_tag="VW749_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175147.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIEN"
     gene            complement(195..968)
                     /locus_tag="VW749_001102"
     CDS             complement(195..968)
                     /locus_tag="VW749_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0175148.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(1414..2169)
                     /locus_tag="VW749_001103"
                     /pseudo
     CDS             complement(1414..2169)
                     /locus_tag="VW749_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2307..3929)
                     /gene="groL"
                     /locus_tag="VW749_001104"
     CDS             complement(2307..3929)
                     /gene="groL"
                     /locus_tag="VW749_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0175149.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3945..4229)
                     /gene="groES"
                     /locus_tag="VW749_001105"
     CDS             complement(3945..4229)
                     /gene="groES"
                     /locus_tag="VW749_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0175150.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(4499..4894)
                     /locus_tag="VW749_001106"
     CDS             complement(4499..4894)
                     /locus_tag="VW749_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0175151.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(4972..5733)
                     /locus_tag="VW749_001107"
     CDS             complement(4972..5733)
                     /locus_tag="VW749_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0175152.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(5766..6392)
                     /locus_tag="VW749_001108"
     CDS             complement(5766..6392)
                     /locus_tag="VW749_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0175153.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(6408..6725)
                     /locus_tag="VW749_001109"
     CDS             complement(6408..6725)
                     /locus_tag="VW749_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0175154.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(6722..7021)
                     /locus_tag="VW749_001110"
     CDS             complement(6722..7021)
                     /locus_tag="VW749_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0175155.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7271..7459)
                     /locus_tag="VW749_001111"
     CDS             complement(7271..7459)
                     /locus_tag="VW749_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEV0175156.1"
                     /translation="MKASTWVYDKGEWYYVSSSGAMLANDWVKDNGKWYYLASSGKML
                     RNTYTPDGYYVGNSGAWQ"
     gene            complement(7710..8384)
                     /locus_tag="VW749_001112"
     CDS             complement(7710..8384)
                     /locus_tag="VW749_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175157.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(8390..8836)
                     /locus_tag="VW749_001113"
     CDS             complement(8390..8836)
                     /locus_tag="VW749_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175158.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(8950..9453)
                     /locus_tag="VW749_001114"
     CDS             complement(8950..9453)
                     /locus_tag="VW749_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0175159.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(9450..9812)
                     /locus_tag="VW749_001115"
     CDS             complement(9450..9812)
                     /locus_tag="VW749_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV0175160.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(9878..11737)
                     /locus_tag="VW749_001116"
                     /pseudo
     CDS             complement(9878..11737)
                     /locus_tag="VW749_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(11776..12225)
                     /locus_tag="VW749_001117"
     CDS             complement(11776..12225)
                     /locus_tag="VW749_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0175161.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(12349..13065)
                     /locus_tag="VW749_001118"
     CDS             complement(12349..13065)
                     /locus_tag="VW749_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0175162.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(13946..15361)
                     /gene="ply"
                     /locus_tag="VW749_001119"
     CDS             complement(13946..15361)
                     /gene="ply"
                     /locus_tag="VW749_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0175163.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(15372..15704)
                     /locus_tag="VW749_001120"
     CDS             complement(15372..15704)
                     /locus_tag="VW749_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175164.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(15775..16383)
                     /locus_tag="VW749_001121"
     CDS             complement(15775..16383)
                     /locus_tag="VW749_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175165.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(16396..16854)
                     /locus_tag="VW749_001122"
     CDS             complement(16396..16854)
                     /locus_tag="VW749_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0175166.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            16979..17378
                     /locus_tag="VW749_001123"
                     /pseudo
     CDS             16979..17378
                     /locus_tag="VW749_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18143..18403)
                     /locus_tag="VW749_001124"
     CDS             complement(18143..18403)
                     /locus_tag="VW749_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175167.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(18462..19013)
                     /locus_tag="VW749_001125"
     CDS             complement(18462..19013)
                     /locus_tag="VW749_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175168.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(19003..19200)
                     /locus_tag="VW749_001126"
     CDS             complement(19003..19200)
                     /locus_tag="VW749_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175169.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(19204..19998)
                     /locus_tag="VW749_001127"
     CDS             complement(19204..19998)
                     /locus_tag="VW749_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175170.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(20406..20831)
                     /locus_tag="VW749_001128"
     CDS             complement(20406..20831)
                     /locus_tag="VW749_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175171.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(20960..21343)
                     /locus_tag="VW749_001129"
     CDS             complement(20960..21343)
                     /locus_tag="VW749_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175172.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(21365..21571)
                     /locus_tag="VW749_001130"
     CDS             complement(21365..21571)
                     /locus_tag="VW749_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175173.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(21558..21731)
                     /locus_tag="VW749_001131"
     CDS             complement(21558..21731)
                     /locus_tag="VW749_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175174.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(22090..23046)
                     /gene="lytA"
                     /locus_tag="VW749_001132"
     CDS             complement(22090..23046)
                     /gene="lytA"
                     /locus_tag="VW749_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0175175.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK"
     gene            complement(23422..24792)
                     /locus_tag="VW749_001133"
     CDS             complement(23422..24792)
                     /locus_tag="VW749_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0175176.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(25106..26272)
                     /gene="recA"
                     /locus_tag="VW749_001134"
     CDS             complement(25106..26272)
                     /gene="recA"
                     /locus_tag="VW749_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0175177.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(26327..27583)
                     /locus_tag="VW749_001135"
     CDS             complement(26327..27583)
                     /locus_tag="VW749_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0175178.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(27668..28684)
                     /locus_tag="VW749_001136"
     CDS             complement(27668..28684)
                     /locus_tag="VW749_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0175179.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(28692..29210)
                     /locus_tag="VW749_001137"
     CDS             complement(28692..29210)
                     /locus_tag="VW749_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175180.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(29200..29643)
                     /gene="tsaE"
                     /locus_tag="VW749_001138"
     CDS             complement(29200..29643)
                     /gene="tsaE"
                     /locus_tag="VW749_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0175181.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(29729..30349)
                     /locus_tag="VW749_001139"
     CDS             complement(29729..30349)
                     /locus_tag="VW749_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175182.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(30732..31595)
                     /locus_tag="VW749_001140"
     CDS             complement(30732..31595)
                     /locus_tag="VW749_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175183.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT         9564 a         6973 c         5368 g         9811 t
ORIGIN      
        1 aaattctcta tcgaaacatt gatatttgat aataattcaa aaaatgttga aagagaaatt
       61 tcattttctc ccctttcaaa tctagaaagt tgagattttg atataaaatc agctgcagca
      121 tactctaaag aatatccgtt taattttcta aaatatcgaa aagcttctcc gtaatttttc
      181 acactttcat tcccttaact ttcttttcga gcgataaaca taccatattc tttaggaatg
      241 atcaacatac cattattaaa ctcactttcc aatcttttac gtattatttc ctcttctagt
      301 gaacctattt ctgaaattcc tttaaacgat tggatgtatt taactaggtc atctatacta
      361 gttacctgta actcatcatc atagagtaat gtatcgacag agttaaaata cctactcagg
      421 taccttttac cattttgtaa agtaaacgtt ctattttcta aatcttgatt aacctcatct
      481 ttaaataaac ttgccaaata atttacaact ccattttcac caaatgtagc acagtaaaaa
      541 atgcctccgg tttttaagac cctattcacc tcagagagag ctttaggaat atcattcaca
      601 tgatgtagaa gcatattagc aataacaata tcaaaagttt cattctcaaa agaaatcttt
      661 tgaatatcca ttatctcata attgacattg tttctatttc caatcactga cttcgttgat
      721 tttaccatat ctttagaaaa atctgtaaca atcaactgct tcattttatc tatagaatca
      781 ctattacttt tccacaattc tcctgtacca catcccaatt ctagaacctt tacttcatca
      841 gtgatttggt agttagaaaa tatccaatta ttaaatccca atttattttt tgaatacttc
      901 ttatgcaatt ctactcgaat atcaagatta tcatgacttt tatattgttc aattacttta
      961 tcaatcattt taaatgacct ccactctata atttggcatt atatcacaag aataaagata
     1021 gtgttaaata agttatataa atgcaaaaaa ggaatattcc gttatagcag agttgtaaca
     1081 catttctata aagaaattta ttcctacgac tcagtttggc atgcttaact tcctaactca
     1141 aaaacaaagc atcgattaat ttatccgttc ttcttttgaa acagatttga actgataatt
     1201 gctcgtttta atttaaaaag ctcttttgag caaaacttca tttttttaag agtccaacaa
     1261 tttctgtcta tcgcttttct actagcaaaa aacctacctt gaggcaagtt ttcatttata
     1321 tatctaattt cgtaacagta tagtaaaatg aaataaggac agtcaaatcg atttctaaca
     1381 atgttttaga agtaaaggtg tactattcta gtttcaatct actataaatt tgatatgaga
     1441 atagtctttc tcaacatcct tatccaacaa gcatgctgtg gcgtccttct taacttaaac
     1501 caggtcaata ttctgggctt gggctgcata gacgcagcca caataacatt gacgatagat
     1561 atcatactcc tcacacatct ctactgaacg tttgtagcct tgatttttct tgaaatcgtt
     1621 gggaagatag tggggcgtgt aaattttttg cacatcgatt ccgatgctat tgatagtttg
     1681 agaattctta tgaggactga tggtcaaggc tgaaccaaag tagtcaaagc ccaagtccat
     1741 agccacttgc gctgttttat ccagtcggta gtcaaaacaa accttgcaac ggtcgccacc
     1801 ttcgggctcc tcctctagcc ccctaactag ttttcggtat taattgggtt cgtagggagc
     1861 ttctaggtac tgaaccgtat ttcctgtccg ctcattaaaa tcactaacaa atttcttggt
     1921 gacatagacc cgcttatggt attctgcctt gggatggata ttagaattgg caaaatagat
     1981 ggtcacatct gcatacttgg tcaaatattc tagtgtatag gtactacaag gggcacagca
     2041 aacatgcacg agaatggttg gccgctactc atttttttcc catgcttgta ccattttctg
     2101 catgacacgg tcataattaa tcttctgatt gggggtcatc ttgcacagaa tttcttctac
     2161 atcgatcatg ttcttctcct ttttctagtc ttattttatc atataagtta ggagagctca
     2221 aatcaattta gaagtgaata ttataaaaag aagggttagt cattccctcc ttttgtgttt
     2281 tttataagtt gttttctata gaaagcttac atcatcccgc ccatcatact tggatccatt
     2341 gctggagctg gggctactgg ttctggttta ttggctacga ctgcttctgt tgtcaaaatc
     2401 aagctggcta cagatgctgc attttgtagg gctgaacgac tcactttaac tggatcaatg
     2461 ataccttgat caatcatgtt aacccactcg ccagttgctg cgttgaatcc tataccaagc
     2521 tcagcatttt tcaaacgatc gataacgata gatccttcaa atcctgcatt gtgagcaatt
     2581 tgacgaacag gttcttccaa agcacggaga acaatattac gtcctgttgc ttcatctcct
     2641 gtcaattcca aggtagcaac agctggaatc acattggcaa gagctgttcc accacctgca
     2701 acaatacctt cttcaacagc tgcacgagta gcgttgaggg catcttcaat gcggagtttc
     2761 atttctttca actcagtttc agttgcggct ccgaccttaa taaccgctac accacctgac
     2821 aatttggcca agcgttcttg caatttttca cggtcaaatt cagaagttgt agtttcgatt
     2881 tgagacttga taaccgcaac acggtgagaa atcgcttcag gatttcctgc accttctaca
     2941 ataaccgtgc tatctttgtc cacggtcact ctcgctgctt gaccaagagc ttcaattgtc
     3001 gcatctttca actcaagacc aaggtcttct gtgataactg ttccgcctgt taagatggcg
     3061 atatcttcaa gcatggcttt gcgacggtca ccaaaaccag gtgccttgac tgctactacg
     3121 ttgaaggttc cacgaatctt gttcaaaaca agagttggaa gagcctcgcc atccacatca
     3181 tccgcaataa tcaagagtgg acgattgctt tggagaatgc tttccaaaag tggcaagatt
     3241 tcttggatat tggaaatttt cttgtctgta atcaaaatgt acggattttc aaggtcagcc
     3301 accatttttt cgctatctgt caccatgtac tgtgaaaggt aaccacggtc aaactgcatt
     3361 ccttctacga cttcaagctc tgtttccata ccacgtgact cttcgatggt gatgacaccg
     3421 tctttgccaa ctttttccat tgcttcagag atgtactcac caactttttc agaacgagaa
     3481 gatacggctg caacttgagc gatagcttct ttattggcaa cagggatggc gttgtttttc
     3541 aaagcttcaa ctgctgcggc aactgctgtt tcaatcccac gacgaatacc gattggattt
     3601 gcacctgctg tgacgttttt gattccttca cggacgattg cttgggtcaa aacagttgca
     3661 gttgtagttc catcacctgc gatatcattg gtttttgaag ctacttctga taccaatttg
     3721 gcacccatat tttcaaaatg gtcttctaat tcaatttctt tggcaatagt cacaccgtca
     3781 ttggtaatca atggtgagcc aaatgatttt tcaagaacga cattgcgacc ttttggtccc
     3841 aaagttactt taacagtatc tgcaaggata tcgacaccac ggaccatggc tgaacgggca
     3901 tctgatgaaa atttaatttc ttttgacata cttactttct ccttctattc ttcaatgatt
     3961 gccaagatgt tagcttcgcc tacgatgatg tacttttcat cgccatcttt gacatcaaga
     4021 cctgcgtggg cttcaactaa gacacggtct ccagttttaa cacttggagc aaccaagtca
     4081 ccgttcaagg tacgaacacc ttgtccagta gccacaactt gggctgtttt ggttttttct
     4141 tgggctgaac ctgcgagaac aaagcctcca acagtttgtt ctttttcttc tacttttaag
     4201 accacacggt cccctaatgg tttcaacatc tgatttcctc cataatgaga tagatattat
     4261 tagcactctt tatacctgag tgctaattca tagttctatt gtatcactta gtcagaaata
     4321 atcaagaaaa aagtctgact ttctcaagat aaaaagcctg agaccaactc agacttttta
     4381 atgtttatac tcaatgaaaa tcaaagatca aactaggaag ctagccgcag gctgctcaaa
     4441 gcattgcttt gatgttgtgg ataaagctaa cgtggtttga agagattttc gaagagtatt
     4501 aaaatggcaa ttcttcctct tccaagacta aatctgccaa atcttggcct gcattatttt
     4561 cacgcatggc acgttgagca cgactttcca agagttggaa tcctgttaca agtacttcgg
     4621 tcacgtagtt catttggcca tttttctcaa agcgacgggt acgcaattct ccatcaacgg
     4681 aaatgagact acctttggtt gcgtagcttg ccaaagtttc tgctagtctg ccccatagga
     4741 ccatattgac aaaatcagct tcacgttcac cgttttggtc tttgtaacga cggttgacag
     4801 cgatagttgc tcgcgctacc gacttgtcat tgttggtttt gtgcaattct ggtgtagacg
     4861 ttaaacgccc aatcatgata actttattat acatattttc ttcctcctac ttatctattc
     4921 gtaggaaatc aaaaaaagtt acagaaattt gtaacttttc gaggaaattt cttatttttt
     4981 atgaatcatg aaacctgtcg cctgttgatt ggccataatg gtcatatctg taatctgaac
     5041 acggcgaggc tgactggtca catagactac tgtgtctgca atatcctgag cttgcaaggc
     5101 ttctattcct tggtaaacgg acgcagctcg ctctttatca ccatgaaaac gaacagttga
     5161 gaaatctgtt tcgacaatcc caggctgaat ggttgtcacc ttgatatccg ttgcgatggt
     5221 atcaattcgc agtccatccg aaaaggtctt aaccgcagcc ttggtagctg agtaaacagc
     5281 ggcaccagca taggcgtaga ttcctgcggt tgaccccata ttgataatat gaccttgatt
     5341 gacttttatc attgctggca agaaacagcg agtaaccgcc atcagacctt taacattggt
     5401 atccaacatg gtcaacatat ccaactcctc atagtcttga tagggagcca agtcaagagc
     5461 cagtccggcg ttgttgacca agatatcaat cctccctatc gtttctagaa tatcagagca
     5521 aacagtcttc accatgacca tatccgtcac atctagtgga aaagtccaga cggtttgatt
     5581 tggaaagctt actgcaaact ccgacttgag gatttctaat ctgtctatcc gtcgtcctgt
     5641 tagaacgaca tcctcaccct gctccagata agcacgcgca atcgcttcac cgattcctga
     5701 ggttgctcct gtaatcacta cattttttgc catcttattt ccttctatca gatgctgaca
     5761 agttcctagg cagtccagtg tttcgctggg tcgaacggtg ttccgacaac ttggtcttct
     5821 gataattcaa gcaccccacg tttttgtgga gcatttggca gatgcaattc acgaggactg
     5881 cacatcatac caaaactctt ttcaccacga agttcacctg ggaaaatgag attccctttt
     5941 ggcatcatag ctccaggaag cgcgacaatg gttttcaacc ccacacgcgc attgggagct
     6001 cctgcaacga tttgtacagt cttatcactt gcgactgcaa cttggcagat gttgaggtgg
     6061 tcactatctg gatgggctac catctcaaca atttcaccga caacaaactt aggttcctta
     6121 tcattaacaa tttcttctgt aaaaccttcc gcctgcaact cttggttcaa acgagcgact
     6181 tgctcatctg tcaaaaagac ttgaccgcgc tctgcaattt caaataaact tgaaacttcg
     6241 aaaatattcc aagccactgt ttccccatta tctttgagaa aaacacgggc taccttgcct
     6301 ttgcgctcca catccagttt ggcatctccg ctatttttca cgatgaccat aaggacatca
     6361 ccgacatgtt ctttattata tgtaaaaatc attgtttcct ttttctccta tttcagtcct
     6421 gctaaaaagt cattgatttg ttgcttgctt ttacggtcgc gattgacaaa acgaccgatt
     6481 tccttgtcct tttctagaac aacaaggcta gggattccat atacatccca gagtttggcc
     6541 aaatctatat actggtctct atccactcga ataaaggtaa actctggatt agtctcctca
     6601 atttctggta aggcaggata gatataacgg caatcgccac accagtccgc cacaaaaagg
     6661 aagaccttct taccgtcttt ttctactaaa gatgccaatt cttctaaact tgctggttgt
     6721 atcataagac ttcctcctca tagactaggt cttcattttc atagacaaaa gtataatgac
     6781 ggccatcctc aaaaatgacg ccaccaagca agctctctag actgctttca tagacttgaa
     6841 catagagggt cgcaatttcc cccatgtctg aaaaatggtc tcgtacaatc gctgtcaact
     6901 cttcctgagt cttcatgagc ttatggtcat ctgcaacttt tttcgtagca agggcaaggc
     6961 tcccaatacc aagcagagcc agacctgcca tccacatttt tttagctttc ataccattca
     7021 ttttaacaca aaaaaggctt taggacaaat gaggaaacag caaaaaagca agtaaaaagc
     7081 ctcttccttt aaggaaaagg acttcttata ctcaatgaaa atcaaagacc aaactaggaa
     7141 gctagccgca ggctgctcaa agcactgctt tgaggttgta gatagaactg acgaagtcag
     7201 ctcaaaacac tgttttgagg ttgtggatga agctgacgtg gtttgaagag attttcgaag
     7261 agtattattc ttattgccag gcgcctgagt taccaacgta gtaaccatca ggtgtgtagg
     7321 tattgcgaag catcttacct gatgaagcta gataatacca cttgccatta tctttgaccc
     7381 aatcattcgc tagcatggct ccagaagaac ttacataata ccattctccc ttgtcataaa
     7441 cccaagtgct tgctttcatg gctcctgagc aattaaaggt tcaaaaaact gtccaatatc
     7501 attcattttt ttaaagcatt ttacactaca tcatccacgc tgtaggacat agatacatca
     7561 aacgtaagag ccaaaatatc gaaaaatata caacttttaa aggcaacatt tcatttttta
     7621 aagtctaaca accatagaac tgaaatcaga gcaaggcatc aacttcctac tcttagtacg
     7681 tctattttga tggttgaagt gaagattttt tatttaacgt agacaagctc caacttccca
     7741 aaagccacat ctccacggat aatcaaggtt ttgctggttg gggctacagg agcgtcagcc
     7801 ttagctgcac caaaggaggt ttctactttc aaatctacac gccagtgttg tggaacatag
     7861 acggttgcat tcccgaaggc cacttcaata tttaaagttg caaaatcacc tagcatctct
     7921 gcattatcat agtagatttt agcatcccca aaagcgactt ccacttggtc atctacgaga
     7981 tcttgatctt gcttatagaa ggtcccgcta ccaaaagcga cttccttatc cgtgacgact
     8041 gtttttttcc cattgtacca ccattttttt tcattccaga acttacttga atgcgtcaga
     8101 taaccaacac caagtaccac caagatgcta gcccaaataa gagaatgatt ggtaactggt
     8161 aacaagtcat aagcgtaatt tgcaatgatg agcgccagta aacctgtaaa aactgccgaa
     8221 gtgagatgac gtctaaggat ggactcaatg gacttataag caaaaaaaac aatacctagt
     8281 aaaggccata ttttaccatc caaagaagga attccaaaat tcccttgcag caagatccaa
     8341 gctgctaaaa ccaataaaac aataccaaat gctttctttt tcatgttttt tacctcatgt
     8401 ttcttagatt ttcttttagg agggattggt aatgccgtga gacatgaacc tccttgtgcg
     8461 tctgataaaa ggaaatggtg cccgttcctg aaaaggactt gtccactgag taaatctgac
     8521 ggatgtttgc gatcgttgac ttggaaactc gattaaaata gcgaggcaag atagactcca
     8581 actcatagag cttgaggcga acctcataag cttccttctg gttatgagcg tagatcttgc
     8641 tcccttctgt ttcaaagaag agaatttctg acaggtctag ataatattca cctgtcccct
     8701 tgtaaaaagt caacctcgga gcctttgact cttgcaagag ccgttgcaag tctgcaattt
     8761 catctgtcaa agtgggggtc ttgatgacaa tttcagtctc ctctaaattg ccgtcaatct
     8821 caattcgtaa cttcatcaca tctcctttct gactctacta tatcaaagct aagttaggaa
     8881 tacaagggca aaaaagcaag tggtcaattt gaagcagtaa gtggttgtag gactagctta
     8941 acttacatgt cagaatagga agaaaaggaa tccccacacc agaccacaag catagccaac
     9001 caagacatcc ttgggataat gaacaccccc taaaaccctc accaacccca gcaaagctga
     9061 aaagatcaag catactaagc caataggtag actagcatgc agacaggcca tggagatgat
     9121 agttgcagaa aagacatggc gactgggcat cgaccgtccc gaactatcct tatcaagaag
     9181 gggacagata tcccaagttt cataaggtct cgggtgattg attttcttac gaaacaggga
     9241 caaggccaca aaacctgatg caggaataag cacataaacc ccaacttgct gaccaagtcc
     9301 tagttgcagg taagtggtga ctagcaagat cagatagacc aggggcatgg cgactgtcat
     9361 caaacgattg aaactgcgta ataggaataa aagaattgga cgactagtta gtctggagct
     9421 gatatttcga taccattctt gataattttt catttatgct tctcatactt ttctagaact
     9481 tgttgagatg ttttcccctt ggcaagccaa tccactagct tgtccaaacg acgtatttcc
     9541 tgcatcagag gatcatcaat ttcctcaata tggacaccgc aaatcttccc tgtaattgca
     9601 attcgttcag ggacataata tggtgcttgt agaaaaaaat ctccgtaagt aacatcccta
     9661 tccagacaag caagaacgtc actcacttca taccctgtca accaactggt cacttggtga
     9721 actgactctg cctttccacc ctttcgctca acttttgcaa tcaaggctaa gtagacagca
     9781 gcaaatttca tattgtataa tttctgactc atacttctct ctttctatgt gtactagtat
     9841 aaataagaaa aagaaggccg tcaagccttt ttttgattta ttcttctgct tcatcttctg
     9901 taaattgact attgtacaag tcagcgtaga agccaccttg cgccatcagt tcctcatagt
     9961 tgccttgctc gatgatattt ccatctttca tgaccaagat caagtctgca tttcggatga
    10021 ttgacaagcg gtgggcaatg acaaaggatg tgcgtccttc catcaaacgg tccatggctt
    10081 tttggatcaa ttcctctgtc cgtgtgtcaa cagaagaagt cgcctcatcc aaaatcaaaa
    10141 gcgatgcatc cttaagaagg gcacaagcaa tagtcaatag ttgtttttgt cctacagaca
    10201 aggtcacggt gtcatccaag atggtatcat agccatctgg caaggtcata ataaagtggt
    10261 gaattcccac agccttacta gcttccatca ttcgttcatc actaatccct atttgattat
    10321 agatgagatt gtctcgaata gttccttcaa agagccaggt atcctgcaag accattgaaa
    10381 aggcatcatg cacttctgaa cgcgtcatag ccttggtatc cacaccatca atgcgaatac
    10441 ttctcttatc aatctcatag aatttcatca aaagattgac aatggttgtc ttaccagccc
    10501 cagtcggccc aacaatggca accctttgac cagcatgagc tgtcacagag aagtcatagt
    10561 cttgaacatt gacaccgtcc accagaattt ctcctgctga cacgtcgtag aaacgtggaa
    10621 tcagattgac cagagttgat ttaccagaac ctgttgaccc aataaaggcc actgtttgac
    10681 cagtttctgc tttaaagcta acatgttcaa taactgcctc cgaatttgcc gcatagcgga
    10741 aggtcacatc cttaaactcg acctgacctt tgaagttttc atcagtcagc tgcacttgaa
    10801 cagggttttg gatagaagaa tgcaaatcta aaacttgatt aatccgctta gcagagacca
    10861 tagttcgggg aagaacgatg aagagtgctc ccatgagaag gaagcccatg acaacctaca
    10921 tggcataaga catgaaaata atcatgtcac taaagagagg cagacgcgct atcggagcag
    10981 cgtcgttaat cacataggcc ccaatccagt aaatcgctac actcaaacca cttgaaatcc
    11041 ccatcatgat aggattcaaa atagccataa gacggttgac aaacaaattc aaacgggtca
    11101 attcatcatt tactgctgca aatttttcat tttgataatc ctctgcattg taggcacgaa
    11161 cgacacgaat acctgttaaa ctctcacgag tgatactgtt cagtttatct gtcaacccct
    11221 gaatcaagga ctgttttgga aaggctagcg tcatcaaaac ggtcgtcatc aggacgttga
    11281 caatcactac cacaagtacg gcccagagcc agtattctga atgacctaaa atcttcccaa
    11341 tagcccagat agccataatt ggaccacgcg ttaccacttg caagcccata gtaatcaaca
    11401 tttgaacttg agtaatgtca ttggtagtac gcgtcaagag gctaggaatt gaaaatttct
    11461 taatctctgt ctgcgagtaa tccaaaactc ggttaaaaat atcacttctc agcctactag
    11521 tataagaagc cgccactcgg gatgcaaaaa atccaactgc aactacggac aagaaggcaa
    11581 gaaaggacat tcccatcatc atgcttgccg gctgccacaa ctcatctaaa ttagtttctt
    11641 gactacctag caaatccgta attttcgaga tataggtcgg cacttccaac tctagataga
    11701 ccgaaaagca agtaaagaga atggctagta aaatcatccc ccattctttt ctactaattc
    11761 ttttggctaa tttctttatt ctctcctcct attcccttga tattttgcct gtagttgacc
    11821 gagaaccttc tcaaaaatca gtaattcatc ttcatcaata tcttccatca actgcttgtc
    11881 tatgcgttca aaaaaagcct taacctgttg catctgagaa cgtgctttgt ccgtcagacg
    11941 aacaaactta gcccgcttat caacaggact cgcctccaat tccaccaaac cattttgcac
    12001 tatacgctta accagattac tagcaacaga cttggtaata ttgagttcct gatcgatatc
    12061 tttaatcaag accaagtctt ggtttttctc gcgattatcc aaaaaatgca caacctgacc
    12121 ttgcggccca cccataaatt caatgccgca acgtttggct tccttttgca ccatcaggtg
    12181 aatttgatga ccaaaacgct taaagactaa catcggttta cccataatct cccccttcta
    12241 aataaaaata gttctctgga gaataattaa atttctatga gaactatttt cttgattaaa
    12301 aaaatcccaa gtgattttct cacttaggat catgttctat aggttaaatt aaaacccatc
    12361 tacgttcgta taaatctttt ggacgtcttc gtcgtcttca agaacgctgt aaagtttttc
    12421 aaaggtttca aggtcttcgc ctgacaattc cacttctgac tgaggaatca tttccaattc
    12481 agtcacttgg aattcttcaa taccagactc acggagggca acgatagcct tgtgaaggtc
    12541 agttggcgct gtgtaaactg tgattgtacc ttcttgtgct tctacgtcat ccacatccac
    12601 atccgcttcg agcaattgct caaagactgc gtccgcatct tcacctccaa atacaataac
    12661 acctttgttg tcaaagaggt aagaaacaga acctgaagcg cccatgtttc cgccgttttt
    12721 accaaaggct gcacggacat tggctgctgt acggttaacg ttagaagtca aagtatccac
    12781 aattagcata gagccatttg gcccaaaacc ttcgtaacgt ccttctgtaa aggtttcgtc
    12841 tgtgtttcct ttggctttat caatcgcttt atcgataatg tgttttggca cttgggcttg
    12901 tttagcacgg tcgataacga atttcaaagc tgagtttgat tctggatctg gatcaccttt
    12961 tttagctgct acatagattt ctacaccaaa ttttgcatat actttagagt tggctccatc
    13021 tttagccgtt ttcttggcta cgatattggc ccatttacgt cccattagga atctcctttt
    13081 ttcacatttt aatctttctt attataacac aagttttttt gattttcact agaggaaatg
    13141 gattttatta gcaaatcaag ctaggatagc actttacctg ctaagatggt cttgcctttc
    13201 tatctttatc aacagacact catccacatt caaaaaacaa actagaccat tatctgcaaa
    13261 tagaaagttt cagccaagtt tgacaaagtc agctcaaatt actgtttgaa gtttgtagat
    13321 ataagcgaca aaaacaatca tactgcacct tttgttgaca gtctactcca gacatatcat
    13381 agttcaagta aatactttga aattcaacag ttcttatagg cgctattgta ttctaagaaa
    13441 tcaatagaag agtttctaag caaacctcta atactcaata aaaatcaaag agcaaactag
    13501 aaagctagcc gcaggttgct caaaacactg ttttgaggtt gcggataggg ctgacatggt
    13561 ttgaagagat tttctaagag tataatttac gtgttcctaa gatggagaag ttagactagt
    13621 acactggcac ttctaaacca ttgctagcaa ttgatttgtt catatttaat ttcatttttt
    13681 ccataaatgg gtattagata taaacagcaa aatatttccg atacgtgtca ttcttgaatt
    13741 tccaatcatc taaaacaagt aaaggataat caatcccctg tatatcaagg aattggctac
    13801 cctttttact tttttacaca tcctgtttga tagactcatt ttaacatcac gagcatactc
    13861 caatggaaat cgctaggcaa gagataaact ttcagatatc cgcagagaga tcatcgcctc
    13921 tttttgtcgc aagcattctc ctctcctagt cattttctac cttatcctct acctgaggat
    13981 agagagttgt tccccaaata gaaatcgtcc gcttacgcac tagtggcaaa tcggtttttt
    14041 cataaaccgt acgccaccat tcccaggcaa gcccggtaca ctctctaatt ttgacagaga
    14101 gattacgaac attccctttt aaaggaatac tagtggtaaa gtgagccgtc aaatcctgcc
    14161 catttctgtc ccaagcctta ggagtcaaga cttccttacc ttgatgatca taggataatt
    14221 catcccaagt aatataatat tgggcaacat aggcaccact atgatccagc agtaaatctc
    14281 cgtttctgta agctgtaacc ttagtctcaa catagtctgt actgttttga aaggtcgcaa
    14341 ctacattgtc acgtaaaaaa gaagttgtat aggaaatcgg caagcctgga tgatctgctg
    14401 taaagcgact gccttcttga atcaagtcct ctaccatatc caccttgcct gttacaactc
    14461 gggcacccga acttgggtcg ccccctaaaa taaccgcctt cacttctgta ttgtccaaaa
    14521 tctgcttcca ctctgtctga ggagctacct tgactccttt tatcaaagct tcaaaagcag
    14581 cctctacttc atcactctta ctcgtggttt ccaacttgag atagacttgg cgcccataag
    14641 caacactcga aatatagacc aaaggacgct ctgcagaaat tcctctctgt tttaaatcct
    14701 ctaccgttac agtatcttga aacacatctc ctggattttt aacagcgtct acgctgactg
    14761 tataataaat ctgcttaaaa ttaacaatct gaatctgctt ttcacctgaa tggacagagt
    14821 taaaatcaat atcaagagaa ttccctgtct tttcaaagtc agaaccaaac ttgaccttga
    14881 gttgttccat gctgtgagcc gttatttttt catactgcat tctagctggg acattattga
    14941 cctgaccata atcttgatgc cacttagcca acaaatcgtt taccgctccg cgaacacttg
    15001 aattgctggg gtcttccact tggagaaagc tatcgctact tgccaaacca ggcaaatcaa
    15061 tactataagt catcggagca cgatcaaccg caagaagagt gggattattc tctaacaagg
    15121 tctcatccac tacgagaagt gctccaggat agaggcgact gtcgttggta gctgttacag
    15181 aaatatcact tgtatttgtc gacaagctcc gcttctttct ttcgataaca acaaactcat
    15241 cgggtagctg attaccctct ttgatgaaac gattttcaat actttctccc tgatgggtca
    15301 agagtttctt tttatcgtaa ttcatagcta gtataaagtc atttactgct ttatttgcca
    15361 tcttctacct cctaataagt tcctggattg agttgcataa actcagactt gttcagcgaa
    15421 atcagccgtg gttggactaa gtgatccaaa atttcctcgt acaattcttc tgagacattg
    15481 cgtcgccgtc tggctagata agaagtcgga ataaccgtat tatccaacat aaatacctta
    15541 tctaagtcaa tcaaggttgg tcttgtaaaa ggattacgag ctagatccgg ctcttctatc
    15601 ataaagttct tgaccaaacg tctggtcaag agagctggtt tgaaggtctg atttttaacc
    15661 aactctttgt ttttagtcat gctgttgtca atacagatat acatatgatt cttcacagcc
    15721 aaatcgctac taatagtcgg aaaaggcaaa taaagagcta caacatctcc tctcttaatc
    15781 aagcaagagc accccctttt ctcctaatgt aacatagaca ggattgacca agtcttctga
    15841 ttgactcaga atttccaaag tttgagtttg gcgcgctgtc aatttagtag catcttgtct
    15901 cttcaataca aaatgcttgt cgccaataac cttgacaata taatccttct ccaaagctga
    15961 ctggtaaatc cacatcagat gttgtctgtc ctgagaactc aagagagaag gattttcaag
    16021 cctcccgata gtctgataaa aatcaaaaac aggagctaac tcctgccaat ctgattggct
    16081 agttgtcaag gctagaaaaa gggctttgcg agctgatact tcttggttag ccttgagagt
    16141 tactttcccc tccaagtttt ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa
    16201 ctgcgagaaa taaaaacctt tcgttcccag acataagtct ttcatgtcgc tttctctagc
    16261 aaataagagc tcaaacattt gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat
    16321 cttttcctta tcggcttctt tttttaacca gagcaagggc gacaggtaac tggattgaga
    16381 catttcctct acctcctact cttttttaac tggagcatct gcactagctg ccacttcttt
    16441 tgactggata ctttcccact ggttaatctc ctctgagata agaccttcgc atgtcttgac
    16501 aaatagggca aaagccttgg tctttcctgc atatttctcc gtttggcatt gatagaggaa
    16561 tttttctttc tccaggagtt gcgcagtttt ttggtaagaa atccaatttt cctttgcatt
    16621 atacaaattg ataatcccct cacacagcaa gccgagactg gataaggcaa ccgaaatcaa
    16681 acggtagcga tcacctggca taggaatagc acaaaagaca gctatgagga aacctgccac
    16741 gatttctgtt atttttaata ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa
    16801 atgagctatc tgtacgtcta atcgctctgt caggtacatt tcttctggcg tcatattcgt
    16861 aactcctttc atttactttg ataaccatag tataacatat ttgaatatca aagtatagta
    16921 aaaactggac tataacttat tagacttcct gcgaaacaaa atatggtata gtagttctat
    16981 gaatgatgaa gcaagtaaac aactaactga tgcacgattt aagcgtcttg ttggtgttca
    17041 gcgtaccact tttgaagaga tgttagctgt attaaaaaca gcttatcaaa aaagtcggac
    17101 aagctggtaa aatcttggct gacagtaatt atcaagggct catgaagata tatcctcaag
    17161 cacaaactcc acgtaaatcc agcaaactca agccactaac agttgaagat aaagtctata
    17221 accatgcgct atctaaggag agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt
    17281 ttaaaatgtt ttcaacaacc tgtcgaaatc atcgtaaacg cttcggatta cgaatgaatt
    17341 tgagtgctgg tattatcaat catgaactag gattctagtt ttgcaggaag tctattatat
    17401 atatgcacag acatatgaaa tctttttgat acagccttct ttttacatag agagacagca
    17461 gttatgatat atttatccat tcacaacatc ttctgtacca atactacaat aattggtaca
    17521 ttttgattac acaatcgttt caaaaaatat gatggaagac tgagtatttt atagtaattc
    17581 ccttcctatc aactagatca accagttgag tgttgaatgt tgaaacaccc tagcctcagc
    17641 aaaggactat gatcagcatt tcctagccaa taggacgctc caaatcacct attctaagtc
    17701 catcactagc ttggtcagta agatacagac tgcaaggcaa gactgacgtg gttgatgaga
    17761 ttttggaaga gtattacaat catagattca ccagtagact tgaccgcaga tttaactata
    17821 gtagattgaa actagaatag tacacttctg cttctaaaac attgttagaa atcgatttga
    17881 ctgtcctgat caatttgtcc tgttctcgtt tcattttact atactaaaaa accacctgaa
    17941 acaaatcaag tgactagagg ataaaaacaa agactgggca aaaagttttg aaaagcaaaa
    18001 aacgcataat atcaggtctt gaaaaacctt gatactatac gtttgattgt gggaagattg
    18061 acttcatttt ctcctgaaat tgaagttttt tctagtttcc aggtatagac gaattcaata
    18121 tagccatctc gctacaatta ttttaaccat cgaaaaaatt tttcagaatt tcaaaaattt
    18181 cattttgatc caatgaaatg tcattatttt gaagaatagt tgacttcaca ggctctaatt
    18241 ctatcacaaa gcggtgcatg tctgctttta ccgcactact tgatgttata gccgataact
    18301 tttcatctcc tagcaaggaa gctgtcaaac gggtaaggtc attcaaatgc tttttaatgg
    18361 acttacttaa accttgagca cctgtggcag agcgctccct catatccagc caagctttag
    18421 ccttaaaaat aattaatact caatgaaaat caaagagcaa actaggaagc tagttgcagg
    18481 ctgctcaaaa cactgttttg aggttgtaga tggaagctga cgtggtttga agagattttc
    18541 gaagagtata gaccacaatt actcaatacc gaatacccct gaatggtttc ttttacatgc
    18601 accaatatat tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca
    18661 aaatataagg gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat
    18721 agttcaatca tagaaggaaa ctcagaatta gttgttgtaa atcgaaaaag ctgcgctttc
    18781 tcatctttct gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa
    18841 aattccttat tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt
    18901 ttaaatcctt gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag
    18961 ttctgaaaat ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc
    19021 tcccagatac tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc
    19081 atcatcatct tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt
    19141 atttttaaaa tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat
    19201 ctttcatttt aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca
    19261 tatgacatag ctaatatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata
    19321 agcaccacca tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa
    19381 taaaatccgt tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt
    19441 ctttgacacc gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa
    19501 agtcctcaaa cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc
    19561 aacatctact actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct
    19621 aggtgttaat tccttaggga cttcagtatc attcgcattg agtactagtc ccaatggagg
    19681 gaagaagagg tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt
    19741 ttcactgtct gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat
    19801 agtgcgagcc tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa
    19861 aaatgattcc ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg
    19921 taaagtcaaa gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat
    19981 tatctttttg acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc
    20041 ggtataataa aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc
    20101 acattaccct acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac
    20161 ttttctctca tccactatgc aggacttact atttcacttc tactcctata ggctcaattt
    20221 gacacttttc tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa
    20281 atttattttt gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca
    20341 ccaattttcc ttctcttttt aagcatatta ttccagatat gattgccctc ttgttcagta
    20401 ataaattacg ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa
    20461 aattcttcta catatgattt aacatctctt aggttattac ttcctaatat cccattatgc
    20521 tttttcgcta aggaaataga agccgcttct cccttaccaa taatcttgtt attatcatga
    20581 tttcttgtta aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc
    20641 tcagctgaac ccttagctac caactgatct atcctagatt ttaaatgggg aattgtaggt
    20701 atattgattt catcatacac ctcttgtgga ataacaattt tacccgaata gagcttttct
    20761 aaaagatgtt cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca
    20821 cgactagtca aacgacaact cccccctctt catctagccc atatacaata tcatatctga
    20881 aagcatctag taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt
    20941 gttcagttga attaatatat tatcctaata ccatttcctt tttactttct gacaaaggac
    21001 gatataaact tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat
    21061 ttttaatttc ttctgcatca aggtatccat cattcctcaa tctatataac atagctttat
    21121 gactgatacc ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat
    21181 tggcattttc tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat
    21241 aagaagcaag ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac
    21301 tgactgaact cttcttcacc tcatcataat aaagatgata cagttcatgt gctaaagaaa
    21361 atctttacct tcctaatgac atgtctgaat tgactgcaat gagactgaac tgagttcctt
    21421 tataacagac tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta
    21481 tcttttgtac caatttaaaa atatctatcg gcgcttcacc atcagctccc aacttttttc
    21541 taagatttga agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt
    21601 ttggcaatca tgctttgatt caaagacaaa tataaagaca aatattcagc aatcttatct
    21661 tgagtaagat ttgaagatat tctaagttct tttattcttt ttccaacatc acatacattt
    21721 atcacataca tttatcatat tcatacacct ctcataaaaa gaatagcaca cttttgtcat
    21781 aattttttaa ataaaaaaat tatgacaaaa caaggaagca atttattgat gctgcttaaa
    21841 aatctaaaat tgatgagttc ctatcaaaaa tcgtatcttc aacctcaaaa cagtacttaa
    21901 agctatccga ctcggtttac attgtcaaat ttagatttta tttgagcata actttctagt
    21961 ttgctttctg atttttgttt aatatagtag caaacattga aggaaatatc tccacaagaa
    22021 aacgcatact attaagcttt ttcaagacct aataatatgc gctgttctga tttgaaagac
    22081 attccattat tattttactg taatcaagcc atctggctct actgtgaatt ctggcctgtc
    22141 tgccagtgtt ccgtctggtt tgaggtagta ccagcctgtt ccgtccgctg actggataaa
    22201 ggcatttgat accatggcgc cttctttagc gtctaagtag taccaagtgt ccttgtactt
    22261 gacccagcct gtcttcatgg caccttcttc gttgaaatag taccacttat cagcgatttt
    22321 cttccagcct gtagccattt cgcctgagtt gtcgaaccag taccagttgc cgtctgtgtg
    22381 cttcctccag cggtctgcaa gcatatagcc tgaactgtca aagtagtacc aagtgccatt
    22441 gattttctca aacttgtctt ttggataaga gccgtctgaa tgtacgtacc agtagccagt
    22501 gtcattcttc tgccagcctg tttcaatcgt caagccgttc tcaatatcat gcttaaactg
    22561 ctcacggcta atgccccatt tagcaagata tggataaggg tcaacgtggt ctgagtggtt
    22621 gtttggttgg ttattcgtgc aatactcgtg cgttttaatt ccagctaaac tccctgtatc
    22681 aagcgttttc ggcaaacctg cttcatctgc tagattgcgt aagagttcga tataaaggcg
    22741 gtagtccgtc atgaactctt ctttggttga atggctttca atcagttcaa ccgctgcata
    22801 ggtctcagca ttccaaccgc ccccaacgtc ccaggcacca ttatcaacag gtcctacctg
    22861 catgatgcaa ccgttcccaa caatgtgcga gaaaaaacct aattctgggt ctttccgcca
    22921 gtgataatcc gcttcattct gtacggttga atgcggattc ccagttgagt gtgcgtgtac
    22981 ttgcctatat ggttgcacgc cgacttgagg caaatctgtt cttaatttac tcacattaat
    23041 ttccatattc tactccttat caattaaaac aactcatttt ttacaatcca gaaccagaaa
    23101 ctcctttatt tctaccttac aaagaagaca atcttagtca cgattaggct tgtagataga
    23161 acttcaaaac gcactatttt gacactgtaa ataggactga caaggtctgc attctatcta
    23221 caataacacc ccagactaaa aagcttttca aaagtatatt tttacagtct ctatatgtcc
    23281 ttttcataaa tactatactt tattatatca tataaaagaa gtcaaaagtc tgttaaacta
    23341 ttttcaacac caaactaaag acgagaacac aagttttttc gattttcact agaggaaatg
    23401 gattttattc agtaaatcca actaggattg cactttggtt gccaagattg ccttgccttc
    23461 ttttatcaag ggatgacgga ataatgagaa gtacagttga actgtcatgg caacccagat
    23521 aagaggttca caaaggataa cacccttata tcctgcccaa ggaataatca aaaccacaaa
    23581 aacgattttt ccgattagtt caataaagct agaaactaga ggaaggatct tttgccccaa
    23641 gccctgcaag caattgcgat aaatcaacaa gaggctcaaa atgggataaa aggttgaact
    23701 gatttgcaga tagagacttc cattttctat caagtaacca tctgtcgaac tagccaagaa
    23761 ggaaaccaaa gctggactgg caaaaaagag gaaaatacaa acaaaaactg cccaggatat
    23821 acttaaacga ctgccgattc gaagaccttg aacaatacgg tcaggtcgct tagctcctag
    23881 attctgagaa gcaaaggtcg tcattgatgc agaaatagcg gtcataggaa gaagggcaaa
    23941 ggtcataatg cgtcgagctg ccgtctgggc actaataatc actgcaccaa atgtattaac
    24001 agaaaactgt aaaatcacac tgccgataga tacaattgaa ctcatcaagc ccatagccaa
    24061 accttgctcc aagagatccg cgtacaagct tttgtcccat ttgaaatgtt taaactgtgg
    24121 caagagttct ggcacacttt tacgaatata ataaaagcag agaaccgctg ataaaccttg
    24181 cgaaataatg gtagcaagtc ctgcggattg aactcccaga tgcaattgcg taataaaata
    24241 gagatccaga accacattaa ccaaggcaga gaaaatcaga aatcccaggg ctgctagact
    24301 gtcaccaata gaccgcaaca agcctgcaaa aagattataa gcaaagctga cacctacaca
    24361 ggtcacaatc atagaaatat attgataaga ttgaggaaga atttctgcag gagtatctaa
    24421 gtattgcaag agaggataca agccaagaaa gcccagcaac ataactagaa tgctcaaaag
    24481 agcacctaaa atccaggtgg ctgctactgc ttccttgatt ttagtgaaat tccgagcccc
    24541 ataataacga gcaatgacaa tccccatgcc attgccaaca ccaagtgtaa agcctacaat
    24601 caggtcaaaa atcgctgtcg tcgctcctac tgcagccaag gattcttgac caagaaatcg
    24661 tccaacaatc aagacatcag cagtgttata gagctgttga aaaatatttg atagcaagat
    24721 tggaaaggtg aagcttaaga gcgagggaag aatcggacca tgtatcaggt ccactgttcg
    24781 ttttttattc ataaagctat tatatcagct ttccagagga gcgacaagaa acagcaaact
    24841 tatatatagc ggaatgaaat aaggacagtc aaatcgattt ttaacaatgt tttagaagta
    24901 gatgtgtact attctagttt cgatctatta tagttggttg agtttggaat agtacgctgt
    24961 agctgctaaa acatttctag aaattaattt gactttccta ataaagttgt tcatatctta
    25021 tttcaagcta ctatatataa tatataatct aaaaacttga atcaaaaatc gaaaaagtag
    25081 cggatttctc cactgcttta acagcttatt cttcaatttc gatttcaagt tcatcgccta
    25141 agtcaagcgg aacttcttca ttcactgctt cttctttctt tggctcatct tttttgtttt
    25201 cagtatcttg ttctgaaact tcttctccat caatcaagcc aaatttagaa cggacttgct
    25261 tatcaatttc atcaaagatt tctgggtgct ctgccaagta tttcttagca ttctcagaac
    25321 cttgcccaat tttttcatct ttgtaagaat accaagcccc tgcttttttg ataatatcca
    25381 aatcgcttgc aatcttcaaa agctcaccag tcttagaaat tccttctccg tacataattt
    25441 caactacggc ttccttaaac ggtggagcta ccttattttt tacaacctta atcttagttt
    25501 ctttaccgac attggtttct ttttgatcac cagttccctt aatttgtgta ttaccacgaa
    25561 catccaagcg gactgaagca tagaatttca aagcacgtcc gcccggtgtt gtttctggat
    25621 ttccaaacat cactccaact ttttcacgca attggttgat aaaaatggca attgttttgg
    25681 ttttattgat agaggcgcca agtttacgca tggcctggct catcatacga gcctgcaaac
    25741 caacatggct atctccgata tctccatcaa tttccgcacg aggaacaagg gcagcaactg
    25801 agtcgactac gacaagatca actgcacctg agtcaatcaa ttttcccgca atctcaagac
    25861 cttgctctcc tgagtctggt tgagacaaga gcaattcgtc aatattgaca ccaagggccg
    25921 cagcataagc tggatcaagg gcatgttccg catcgataaa ggcagcaatc ccaccttctt
    25981 tttgcgcttg tgcaactgca tgaagggcaa ccgttgtctt accagatgac tctgggccat
    26041 agatttcgat gatacgtccc ttaggataac cacctgagcc aagggcaatg tcaagagcta
    26101 aagaacctga gctcatcact tgcacctttt gctccgcacg ttcacccaaa cgcatgattg
    26161 atcctttacc aaagtctttc tcaatcaatt taagagcgtc attcaaggcc ttttcacgtt
    26221 ctgccccaaa tttttttgaa atttcttcta atttttttgg ttttttcgcc attctattct
    26281 cctacattct aatgatcctc agacctatct actattatat caaaagttag tcacttaata
    26341 aagccttgcg aactaggtta aaggcatgca taaccgcaat gtgacgtaca tctgctcggc
    26401 ttctgcctcc aatattaacc ttgataacct cagttccttg atcttgcgcc aagcctatga
    26461 agactgtccc aactgggtgt ccttctaggc tatctggtcc tgccactcca gtcaaactaa
    26521 ttccaaaatc agactgggtc ttgcttcgtg cctgctcagc catcttctga gctgtaaatt
    26581 cagacaccac accatgttct tccaaattct tggcaggaat atccaacatc cttgattttt
    26641 cctccaagct ataggtcaca aaaccaccct caaatatact tgaaactcca gaaaaattcg
    26701 ccacggtagc ttggaaaaga cctgccgtca aactctctgc agccgcgatg gttttccctt
    26761 gccttttcag ttcttctacc acaatgctgg ctaaactagt ttcttcccca taaccatagc
    26821 aaaagtctcg taaagaaatt ccttcgaaag tctggcagtc caagatttga ttttccaaga
    26881 tatccagcgc ttgattcgcc tcttcttgac tgctagcctt tgttgacaga cgtagagtga
    26941 cttctcctgt cttggcataa ggggccaagg taggatcgat ctgattatca attaaatcag
    27001 ccaaaatcgt aaccaactgg ctctcgccaa tcccaaagaa acgaagaact cgggaataca
    27061 gcttgctccc tgtcatcaac ttgggtagaa gttggtttaa gaccatgggt ttcaattcac
    27121 ttggcggacc tggaaggacg acataggtca ctccgtctac ttctaatttt cctccaacag
    27181 ccagtcctgt ttcgtttggc agtggaatcg ctccttctac aatttgagct tgtctttcgt
    27241 tattcggtgt tcgggcatag tctggtcgca gggcaaaaaa gatatccaac ttctcctgag
    27301 cctgaggatc aaagactaat gctttcccta aaaatttagc tagggtttgt ttggttaggt
    27361 cgtcctcagt tggccccaaa ccgcctgtca aaatcaccag actgctacgt tgactggcaa
    27421 tctcaagcaa agacaagaga cgaacttcat tgtctcctac agccgtctga aaatatacat
    27481 ctaccccaat ctcagctagt ttttccgaca aaaactgggc attggtgttg acaatctgtc
    27541 ctgtcaaaat ctctgttcca acagcaatga tttctgcttt catgtttcct cctacctatc
    27601 tattcgtatt tttttgaaaa aatcgcagga attttcctac gattgatttt tttatttgta
    27661 tcaaaagtta attatcttca tcaccaacag gtgctctgcc aaataaatct tcaaataaaa
    27721 ccgcattggt ttcaagctga gtaacttctt cttgtcccaa agaacgtcgg agtatatttt
    27781 gcatttccaa catatgtgct ctcgaaacaa tctggtaaga aacaccttga agtatctctc
    27841 cttcaccctg caactgctga gtttcaatgg ttttaaatga atctttatag cctagcaagt
    27901 tagggatact ttttgcagac aaatcaatat tggtctgcat attgtcactc aaagctttta
    27961 gaatctcttg ataatgacca atgctattta aactgagagc tttttccatg actttttgaa
    28021 taacttcacg ttgacgtttt tgacgaccat aatccccctc aggatcttgg taacgcattc
    28081 gtgcatagac tagggcttct tctcccccaa tatgttgctc cccaacaccg atagaaatgg
    28141 tattaaattc ttcttggtca ctgatagaaa ttgggaaacc taggatatta ttgactgtaa
    28201 tacctcctac tgcatccact aatttttgca accctctcat attgaccatc acatagcgat
    28261 caatatggat attcatcatt ttttgaatgg tttctatagc aagctctgct ccaccatctg
    28321 catatgctga gttcagtttc gcttcatgag cctgaccatt ccctgattca atgcgcgtca
    28381 gaatatcccg ctctaaactc atcattgttg tttttttcgt tttaggattc actgtcatca
    28441 agatcatgct atcacttcta ccgacccaag tttcagttcg ttcaacattt ccggtgtcca
    28501 ctcccattaa cagaatggtt agaggttcag tcgcttcaat aaccttggtt tcttcaccga
    28561 tttttttata ggttttagct aaggtttctg tcccttgttg ataaatagta taagcaaaaa
    28621 cacctactcc tactacagtt acagaaagta aagctagcac cattccaata atttttttaa
    28681 ccatatttct actaacctat cagtttaccc atcaagtaaa catcgataaa tttcccttct
    28741 tctatatatg ccccacgctc ttggctacct tcaatgacaa agccatgctt ttgataaaga
    28801 tggactgctg cttgattacg agtttggaca gtcagttgga gacgacgcag aatgccactt
    28861 gcttgtgccc actctatcgc ttcttctagc aacaaacttc ccaagccatt attccaatat
    28921 ctttttccaa tcacaatgaa gagatctcca atatgacgga ctctcttacg ctgatcagct
    28981 gtaatattta caataccagc aattttgcca tttaagaatg caagtaaggt tatctgattg
    29041 tccgaactag cttgcttgtt gaggaatatt tccatctcct cactagtcaa gagaatacca
    29101 tctccgtcta ggctggtaaa gtctgtctcc aaactcacac gatttaaaaa ggccactaat
    29161 tcagctgcat ctttgggctc tgcttcccta atgagcaatt catactccat attgaagctc
    29221 ctctaacaat ttctcagcac gcaaaccctt tgcctgaaaa tttaaacggc gtccatctgc
    29281 ttcttttaga atttccaatt ctaaataagc atctggcaag gcatctccta agagatttcc
    29341 ccactcaata acagtcacgc cgccaccaaa gataaactca tccaagtcga tagaatcagc
    29401 atctccttca atacgataaa catctaggtg ataaagtgga agtcgacctt catactctct
    29461 cacgatagta taggtgggac ttttaatcat ttgagaaatc tgtaatcctt ttgcaagtcc
    29521 tttagtaaag gtcgttttac ctgcacccag ttctccagtt aagattaaaa catcattctt
    29581 tgctaataga tggcccaaac gctcccctaa ggcttgcaac tcttcttcat tttttgtgta
    29641 catactctta ttataccaaa aacttttctt ttgtgtctat tttcctacta aacttatcat
    29701 cataacatcc ataaaaaaca ggctttctct aaaagaaaat gagcgtaaca atgaccaata
    29761 caagatctcg gaaaatatga ccataaaagg aaacttcctt cttaaccgaa tttgggacaa
    29821 gataggctgc aaaaaacaag cccagtccaa tataaatcag aagtgagaca atggtcattg
    29881 gatttcttaa gaaaagaagt gttgctaaaa tagtcaccaa cactgtcttt tttctgtcca
    29941 gcatagcaag aaaatcgcgc acgtattttt tcaagggtaa aaaaatcagc aaatctagcc
    30001 caaataggaa aaagaaggat ggcaataaaa agtcaactaa ttcttgctgc agcgtatttt
    30061 tgatgaacaa gttatctgac aaaacaagaa cagctcctaa caaattaatt aagagtaaca
    30121 tactgtaaaa aagcttcacc gacttcttac tggctaggac actatggact tcttgcttac
    30181 gggtataaag ataatttact ccagcacaga ttcctgaaac gaaaaccatg cttccgatga
    30241 aaaaagctgt actttgttta aaggacaaga tgcattcctt ccataggaaa cagctactca
    30301 aactgatttg aattaaagct aacaaaaata agattctcat tgatttcatc ttctctctcc
    30361 cttcctacca atcattatac taggagaaaa gagagaactg tttctaatct tctcaaatgt
    30421 ctctttaaga cgctaaacaa acactagaga ctaatactca atgaaaatca aagatcaaac
    30481 taggtagcta gccacaggtt gctcaaaaca gtgttttgag attgcagata gagctgacgt
    30541 gatttgaaga gattttcgaa gaatataaat ttgaaatcat gaaaatccgt caaacgggtg
    30601 attgttttgt ctcgcacctc acggagcgag acggactcag agtcacataa ttataaggct
    30661 gatagtatta atctaactat cagccttaca ggttatttaa cgtttcagaa aaactataat
    30721 gtcaagatta actaaacagt atctagttcc ttcaaataat tttctatctt catcaacatt
    30781 aaaggattgt tataaatctt acataactct cttgcttcta tataataatt tttgacttgt
    30841 tctctgtcta gaaatttggc tccagcattt cctacaagaa taagtagagg agccaattgg
    30901 tagcttgtct gtctttgttt acagagttca atcgtttcaa gagcttcttg gatggcttca
    30961 ttatattttt cctttgatac taggtagtga gcgtagttgt aacgaactct gatgtagcca
    31021 aataaaaact cttgatggtc caaatttttt gtctgataca actctattaa atgagagtag
    31081 tttgcctcat attcttgttc acgacccact aaggaataga aattagatag agtattcaac
    31141 gcctttaaat aaatcagagt atttgaagag acttttaata atatattttc caatgacgaa
    31201 attgcctcac acttactgtc atattgatag aagtcaatta tagatttaat ccattcaagg
    31261 taagttcggt cttctaatgt tagaaaagtg cttcgttcta cctctatttt ataaagatat
    31321 tctaaatcgt cataatttct gtcatctaat aggcgagcag atagatgttt gaaattagag
    31381 aggttagact taacttcgat ttgttcattg aaaaagtaat ccaaagggac ttcaagtcgt
    31441 tgagagagtt tgaataacaa gtctgcggag ggaataaaat gacctctttc aattttacta
    31501 atctggcttt gttcacaaat tccttctgca agagtttgtt gggagagtct caactctttt
    31561 cttttcaatc tgaatttctc tgcgagtgta ttcattaaag ataataaacc ttcctatttg
    31621 cttaatttca ttataaagtt tttagttcaa aatagcaagt taaaggaata aataattctt
    31681 tatggtaata aacaaaaaaa aaagttaaaa attaca
//
LOCUS       DAVKUR010000023        27237 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKUR010000023 DAVKUR010000000
VERSION     DAVKUR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.023"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            200..769
                     /locus_tag="VW749_001141"
     CDS             200..769
                     /locus_tag="VW749_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175184.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            837..1487
                     /locus_tag="VW749_001142"
     CDS             837..1487
                     /locus_tag="VW749_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV0175185.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            1471..3711
                     /locus_tag="VW749_001143"
     CDS             1471..3711
                     /locus_tag="VW749_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0175186.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            3891..4079
                     /locus_tag="VW749_001144"
     CDS             3891..4079
                     /locus_tag="VW749_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175187.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            4111..4698
                     /locus_tag="VW749_001145"
     CDS             4111..4698
                     /locus_tag="VW749_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175188.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMTDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            4702..5877
                     /locus_tag="VW749_001146"
     CDS             4702..5877
                     /locus_tag="VW749_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175189.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    6051..6182
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            6198..6728
                     /gene="infC"
                     /locus_tag="VW749_001147"
     CDS             6198..6728
                     /gene="infC"
                     /locus_tag="VW749_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0175190.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            6761..6961
                     /gene="rpmI"
                     /locus_tag="VW749_001148"
     CDS             6761..6961
                     /gene="rpmI"
                     /locus_tag="VW749_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0175191.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            7013..7372
                     /gene="rplT"
                     /locus_tag="VW749_001149"
     CDS             7013..7372
                     /gene="rplT"
                     /locus_tag="VW749_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0175192.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            7430..7810
                     /locus_tag="VW749_001150"
     CDS             7430..7810
                     /locus_tag="VW749_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0175193.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            8060..8860
                     /locus_tag="VW749_001151"
     CDS             8060..8860
                     /locus_tag="VW749_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0175194.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            8823..9809
                     /locus_tag="VW749_001152"
     CDS             8823..9809
                     /locus_tag="VW749_001152"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0175195.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            9851..11752
                     /locus_tag="VW749_001153"
     CDS             9851..11752
                     /locus_tag="VW749_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV0175196.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(11813..13468)
                     /gene="pavA"
                     /locus_tag="VW749_001154"
     CDS             complement(11813..13468)
                     /gene="pavA"
                     /locus_tag="VW749_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0175197.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            13573..14070
                     /gene="ybeY"
                     /locus_tag="VW749_001155"
     CDS             13573..14070
                     /gene="ybeY"
                     /locus_tag="VW749_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0175198.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            14051..14446
                     /locus_tag="VW749_001156"
     CDS             14051..14446
                     /locus_tag="VW749_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0175199.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            14463..15362
                     /gene="era"
                     /locus_tag="VW749_001157"
     CDS             14463..15362
                     /gene="era"
                     /locus_tag="VW749_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0175200.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            15411..16235
                     /gene="mutM"
                     /locus_tag="VW749_001158"
     CDS             15411..16235
                     /gene="mutM"
                     /locus_tag="VW749_001158"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0175201.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            16235..16840
                     /locus_tag="VW749_001159"
     CDS             16235..16840
                     /locus_tag="VW749_001159"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0175202.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            16827..18026
                     /locus_tag="VW749_001160"
     CDS             16827..18026
                     /locus_tag="VW749_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0175203.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            18026..18175
                     /gene="rpmG"
                     /locus_tag="VW749_001161"
     CDS             18026..18175
                     /gene="rpmG"
                     /locus_tag="VW749_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0175204.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            18215..18448
                     /gene="secG"
                     /locus_tag="VW749_001162"
     CDS             18215..18448
                     /gene="secG"
                     /locus_tag="VW749_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0175205.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KVRGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            18550..20904
                     /gene="rnr"
                     /locus_tag="VW749_001163"
     CDS             18550..20904
                     /gene="rnr"
                     /locus_tag="VW749_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0175206.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAANYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            20867..21334
                     /gene="smpB"
                     /locus_tag="VW749_001164"
     CDS             20867..21334
                     /gene="smpB"
                     /locus_tag="VW749_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0175207.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            21350..22210
                     /gene="tehB"
                     /locus_tag="VW749_001165"
     CDS             21350..22210
                     /gene="tehB"
                     /locus_tag="VW749_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0175208.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            22283..23236
                     /gene="coiA"
                     /locus_tag="VW749_001166"
     CDS             22283..23236
                     /gene="coiA"
                     /locus_tag="VW749_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0175209.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            23255..25057
                     /gene="pepF"
                     /locus_tag="VW749_001167"
     CDS             23255..25057
                     /gene="pepF"
                     /locus_tag="VW749_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0175210.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            25059..25772
                     /locus_tag="VW749_001168"
     CDS             25059..25772
                     /locus_tag="VW749_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0175211.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            25839..26780
                     /gene="prsA"
                     /locus_tag="VW749_001169"
     CDS             25839..26780
                     /gene="prsA"
                     /locus_tag="VW749_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0175212.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFKKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(26897..>27237)
                     /locus_tag="VW749_001170"
     CDS             complement(26897..>27237)
                     /locus_tag="VW749_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0175213.1"
                     /translation="LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLS
                     PVQYRTKSFR"
BASE COUNT         8248 a         4983 c         6109 g         7897 t
ORIGIN      
        1 tcttttggga ttccgattaa cattgagata acctaccttt caattgacgg tcttgttttg
       61 gttgtcacat tccagttcat aaatcaaaaa tgtgacggtt tcattgtata tgaaaccgct
      121 tcaaaaatca agaaaaactt gtcatccaaa tttttttatg ctagactagt gaaaatcaag
      181 ctctaatgga gggaaaagta tggaatcaat atttgtgaaa tttgcccagt atccgtctat
      241 agaaacggag cgtttattgc ttagacctgt aactttggat gatgcggaag caatgtttga
      301 ctatgcctcg gacaagggta atacacgtta cacttttcca accaatcaaa gcttggaaga
      361 aaccaagaat aacattgctc agttctactt ggctaatccc ttgggacgtt gggggattga
      421 attaaaagat aacggcaagt ttatcggaac tattgactta cacaagattg atcctgttct
      481 taagaaggca gctattggct acattatcaa taaaaagtat tggaatcaag gattaacgac
      541 agaagccaat cgtgctgtga ttgagctagc ttttgagaag atagggatga ataagttgac
      601 tgcccttcac gataaggcta atcccgcgtc aggaaaggtc atggagaaat caggcatgcg
      661 tttttcccat gcagaaccat atgcttgtat ggaccagcat gaaaaaggcc gaatcgtgac
      721 aagagttcat tatgtcttga ccaaggaaga ctattttgca aataaataag cagttgaaaa
      781 gaaatttttc gactgttttt tcttcctctt acgaataatc taagagagga gaaaatatgg
      841 aagcaattat cgagaaaatc aaagagtata aaatcatcgt catctgtact ggtctgggct
      901 tgcttgtagg aggatttttc ctgctaaagc cagctccaca aacatctgtc aaagagacga
      961 atttgcaggc tgaagttgca gctgtttcca aggactcatc gaccggaaag gaagtgaaca
     1021 aggaagagaa ggaagaacca gttgaacaag atctaatcac agtagatgtc aaaggtgctg
     1081 tcaaatcgcc agggatttat gacttgcctg taggtagtcg agtcaatgat gctgttcaga
     1141 aggctggtgg cttgacagag caagcagaca gcaagtcgct caatctagct cagaaagtta
     1201 gtgatgaggc tctggtttac gttcctacta agggagaaga agcagttagt caacagactg
     1261 gttcggggac agcttcttca acaagcaagg aaaagaaggt caatctcaac aaggccagtc
     1321 tggaagaact caagcaggtc aagggactgg gaggaaaacg agctcaggac attattgacc
     1381 atcgtgaggc aaatggcaag ttcaagtcag tagacgagct caagaaggtc tctggcattg
     1441 gtgccaagac catagaaaaa cttaaagact atgttacagt ggattaagaa tttctctatt
     1501 cccctaattt acctgagttt tctgttacta tggctttact acgccatttt ctcagtatcc
     1561 tattttgctt tgttgggttt tgtttttctg ctagtctgcc tctttatcca atttccttgg
     1621 aaatcagcag gtaaagttct agtgatttgt ggagtctttg gcttctggtt tctgtttcaa
     1681 acttggcaac agagtcaagt gagtcaaaat ttggtggatt ctgttgaaag ggtacggatt
     1741 ttaccagaca ctattaaggt taacggtgac agtctgtcct ttcgtggtaa gtctgatggt
     1801 cgtgctttcc aagtctatta taaactccag tccgaggagg agaaagaagc ctttcaagct
     1861 ttaactgacc ttcatgagat aggactagaa gggaagcttt cggagccaga agggcagaga
     1921 aattttggtg gctttgacta ccaaggctat ctgaagactc agggaattta ccagacactc
     1981 aatattaaaa gaatccagtc actccaaaag gttggcagtt gggatatagg tgaaaacctg
     2041 tccagtttac gtcgaaaggc tgtggtttgg attaagatgc acttcccaga ccctatgcgc
     2101 aattacatga caggactctt gctaggacat ctggacaccg attttgagga gatgaatgag
     2161 ctttattcca gtttaggaat tattcacctt tttgccttgt caggtatgca ggtagggttt
     2221 ttcatggacg gatttaagaa actactttta cgattgggct tgacacaaga aaagttgaag
     2281 tggctgactt atcccttttc ccttatctat gcgggactaa ctggattttc agcatcggtt
     2341 attcgcagtc tcttgcaaaa gctactggct caacatgggg ttaagggctt ggataatttt
     2401 gccttgacgg tgcttgtcct ctttattgtc atgccaaact ttttcttgac agcaggagga
     2461 gtcttgtcct gtgcttatgc ttttatcctg accatgacca gcaaagaagg ggaggggctc
     2521 aaggctgtta ctagtgaaag tctagtcatc tccttgggca tattgcccat tctatccttc
     2581 tattttgcgg aatttcaacc ttggtctatc cttttgacct ttgtcttttc ctttcttttt
     2641 gacttggtct tcttaccgct cttgtctatc ttatttgtcc tttcctttct ctatccagtc
     2701 attcagctga actttatctt tgaatggtta gagggcatta ttcgcttggt ctcgcaggtg
     2761 gcaagtagac cgcttgtctt tggacaaccc aatgaatggc ttttaatcct attgttaatt
     2821 tctttggctt tggtctatga tttgaggaaa aacattaaaa agctaacggt attgtgctta
     2881 ttgattacag ggctctttct cctgaccaag catccactgg aaaatgaaat caccatgctg
     2941 gatgtggggc aaggagaaag tattttccta cgggatgtaa ctgggaaaac cattctcata
     3001 gatgtaggtg gtaaggcaga atcttataag aaaatcaaaa aatggcaaga aaagatgacg
     3061 accagcaatg cccagcgaag cttgataccc tatctcaaaa gtcgaggagt agctaagatt
     3121 gaccagctaa ttttgactaa cacggacaag gagcatgttg gagatttgtc agagatgacc
     3181 aaggctttcc atgtagggga gattctagta tcaaaagaca gtctgaaaca gaaggaattt
     3241 gtggcagaac tacaggcgac tcaaacaaag gtgcgtagta tgatagtagg ggagaacttg
     3301 cccatttttg gaagtcagtt agaagttcta tctccaagga aaatgggaga tggaggacac
     3361 gatgataccc tagttctgta tgggaaattc ttggataagc aatttctctt cacgggaaat
     3421 ttggaggaga aaggagagaa ggacttgctg aagcactatc cagacttgaa agtaaatgtt
     3481 ttgaaagcta gccaacatgg caataaaaaa tcatcaagtc cagcctttct agaaaaactc
     3541 aaaccagagc ttactcttat ctcagttgga aagagcaatc gaatgaaact cccccatcag
     3601 gaaacattga cacgactgga aggtatcaat agcaaagttt atcgaactga ccagcaagga
     3661 gctatacgtt ttaaggggtt ggatagttgg aaaatcgaaa gtgttcgata ggaaggataa
     3721 atgttgtaga ttagtgaaat aaactaaaaa tttgttgcat aataatgata aaaacggcat
     3781 aatgaaaacg tattcaatat tgaggatata aaatcattaa aaatcagcaa aagttgtttt
     3841 agttagttag tttataatct attggtcttc ttcagtccag tgtatctgct gtgacagtca
     3901 ctaaaagtta caagtatgat tggaatacgg ttttggaata tagtaccaac tatcacgacc
     3961 atcagtatgc ttggattccg gaatggtctc gttattacag ctattctgag tataaagttg
     4021 gcggaggctg gaactacgct cgttatgagg tcataaacta ctatactgga agttattaat
     4081 ccttaaagag tgagaaaagg agggctggat atgttaaatc ttactcatgt taccttaaaa
     4141 acgcgacaag tcatcttgca agatgcggat tttaccttta aaaagggtag gatttatggc
     4201 cttcttgcta tcaatggctc gggaaagacg acactattcc gagctatgag caagttgctt
     4261 ccccttagta gtggacacat cgcagttcct ccttctttgt tttattatga gagcgttgaa
     4321 tggctggatg gaaacttaag tgggatggac taccttcgtc tcataaaaaa catctggaag
     4381 tcagacctaa acttgagaga tgaaatcgcc tactgggaaa tgactgacta tatcagtctt
     4441 cccatccgca agtattcctt agggatgaag caacgcttgg tgattgctat gtattttctc
     4501 agtcaggcca aatgctggct catggatgag attacaaatg gcttagacga gtattatcga
     4561 cagaagtttt ttgataggct agcacaaatc gatagacaag aacagctggt tcttttaagt
     4621 tcccactata aggaagagtt ggttgatatc tgcgatagag tagtaaccat tcatcagggg
     4681 cagatagaag aggtttagtt tatgaaagat gttagtctat ttttattgaa aaaagttttc
     4741 aaaagtcgtt taaactggat tatcttagct ttatttgtat ctgtactcgg tgttaccttt
     4801 tatttaaata gtcagactgc aaactcacac agcttggaga gcaggttgga aagtcgcatt
     4861 gcagccaacg agagggctat caatgaaaat gaagagaaac tctcccaaat gtctgatacc
     4921 agctcggagg aataccagtt tgctaaaaat aatttagacg tgcaaaaaaa tcttttgacg
     4981 cgaaagacag aaattctaac tttactaaaa gaagggcgct ggaaagaagc ctactatctg
     5041 cagtggaaag atgaagagaa gaattatgaa tttgtatcaa atgacccgac tgctagctct
     5101 ggcttaaaaa tgggggttga ccgcgaacgg aagatttacc aagccctgta tcccttgaac
     5161 ataaaagcac atactttgga gtttccgacc cacgggattg atcagattgt ctggatttta
     5221 gaggttatca tcccaagctt gtttgtggtt gcgattattt ttatgctaac acaactattt
     5281 gcagaaagat atcaaaatca tctggacaca gctcacttat atcctgtttc aaaagtgaca
     5341 tttgcaatat cctctcttgg agttggagtg ggatatgtaa ctgtgctgtt tatcggaatc
     5401 tgtggctttt cttttctagt gggaagtctg ataagtggtt ttggacagtt agattatccc
     5461 tacccaattt atagcttagt gaatcaagaa gtaactattg ggaaaataca agatgtatta
     5521 tttcctggct tgctcttagc tttcttagcc tttatcgtca ttgtggaagt tgtgtacttg
     5581 attgcttact ttttcaagca aaaaatgcct gtcctctttc tttcactcat tgggattgtt
     5641 ggcttattgt ttggcatcca aacaattcag cctcttcaaa ggattgcaca tctgattccc
     5701 tttacttact tgcgttcagt ggagatttta tctggaagat tacctaagca gattgataat
     5761 gtcgatctaa attggagcat gggaatggtc ttacttcctt gcctgattat ctttttgcta
     5821 ttgggaattc tatttattga aagatgggga agttcacaga aaaaaagaat tttttaatag
     5881 attctagctt tcctataggt agggaaaata agtaaaaact aacatagaga gggaatcaac
     5941 ttgattctct ctttttgatt cgaaaaccaa accaaaatac aaacacaaac ttttcaaaaa
     6001 ataacttttt atcttgacaa gagctagaaa acttggtatc atataaaagt tgagaaaagc
     6061 agaagtgaga gcttctcgcc ttgtgacatt aagttgcctg gccctacgga tgaaaagttt
     6121 cgaagaaacg ctatcataac gtgcgggctt gtatatttac gagtccgcta ttgtttttct
     6181 ctaataaaac aaaagaggtg aaaaccatag caaagcaaga cttattcatc aatgatgaga
     6241 ttcgtgtacg tgaagttcgc ttgattggtc ttgaaggaga acagctaggc atcaagccac
     6301 tcagtgaagc gcaagctttg gctgataacg ctaatgttga cctagtattg attcaacccc
     6361 aagccaaacc gcctgttgca aaaattatgg actacggtaa gttcaaattt gagtaccaga
     6421 agaagcaaaa agaacaacgt aaaaaacaaa gcgttgttac tgtgaaagaa gttcgtctaa
     6481 gtccaactat tgacaagggt gactttgata caaaacttcg taatgcacgt aagttccttg
     6541 aaaaaggaaa taaagttaag gtatctattc gctttaaggg tcgtatgatt acccataaag
     6601 agattggtgc aaaagtttta gccgagtttg ctgaagcaac tcaagatatt gccatcatcg
     6661 aacaacgtgc taaaatggat ggacgtcaaa tgttcatgca attggcgcca gcgactgaca
     6721 aaaaataatt gtcagaaagt taaataaagg agaaaaaatt atgccaaaac aaaaaacaca
     6781 ccgcgcatca gctaaacgtt tcaaacgtac aggttctggt ggacttaaac gtttccgtgc
     6841 ttacacttct caccgtttcc acggaaaaac taagaaacaa cgtcgtcatc ttcgtaaagc
     6901 atctatggtg cattcaggag attacaaacg tatcaaagca atgcttactc gcttgaaata
     6961 atagcttgac tgtaagtaaa caattctagg aaatatttgg aggaaataaa acatggcacg
     7021 tgttaaaggt ggcgttgtat cacgcaaacg tcgtaaacgt attcttaaat tagcaaaagg
     7081 ttactatgga gctaaacaca tcttgttccg tactgcaaaa gaacaagtaa tgaactctta
     7141 ctactatgca taccgtgacc gtcgtcagaa aaaacgtgac ttccgcaaat tgtggatcac
     7201 tcgtatcaat gcggcagctc gtatgaacgg actttcatac tcacaattga tgcatggttt
     7261 gaaattggct gagatcgaag ttaaccgtaa aatgcttgct gacttggctg ttaacgatgc
     7321 agtagctttc acagctcttg cagatgcagc taaagcaaaa cttggtaaat aacaactgat
     7381 gagactggaa caggattgtc cagtcttttt aaaaataaag gagaaaaata tggcttcaaa
     7441 aatgctacac acttgcttac gagtagaaaa tcttgaaaaa tcaatcgcat tttatcaaga
     7501 tgcttttggt tttaaagaat tgcgtcgcag agattttcca gaccatgcct tcacgattgt
     7561 ctatctaggt cttgagggtg atgactatga gttggagttg acttataact acgatcacgg
     7621 tccgtatgtg gttggtgatg ggtttgccca tatcgccctc agtacacctg atcttgaggc
     7681 acttcatcaa gaacacagtg caaaaggcta tgaagtgact gagccaaatg gtctaccagg
     7741 aactacacca aactattact ttgtcaaaga ccctgatgga tataaggtcg aagtcattcg
     7801 tgaaaaataa tttcgtgcaa gttaagtaga atattcgttt tttacttgac tttttttagc
     7861 tgaaagagta tactaataaa aattcaacct ttaaggggag tccagagaga ctcacaaggt
     7921 gtcagataaa agaatagtgc aattttctag aggagacttt ttgagtgtgc tctcttgtgt
     7981 tgtacgattt taactgaggc cttgcactag caaggtcttt tctttatctg gtccccttaa
     8041 aatttaagga ggaaaagtta tgaatcccac atgtaagaag cgtttgggtg tcattcggtt
     8101 ggaaaccatg aaggtggttg cacaagagga aatcgcgcca gcaatctttg aattagtcct
     8161 agaaggagaa atggttgaag ccatgcgagc aggccaattt cttcatctgc gtgtaccaga
     8221 cgatgcccat cttttacgtc gtcctatttc aatttcgtct attgacaagg caaacaagca
     8281 gtgtcacctc atttatcgga ttgagggagc tgggactgca attttttcaa ccttaagtca
     8341 gggagacact cttgatgtga tggggcctca gggaaatggt tttgacttgt ctgaccttga
     8401 tgagcagaat caggttctcc ttgttggtgg tgggattggt gttccaccct tgcttgaggt
     8461 ggccaaggaa ttgcatgaac gtggagtgaa agtagtgaca gtcctcggtt ttgctaataa
     8521 ggatgctgtt attttgaaaa cggaattggc tcagtatggt caggtctttg taacgacaga
     8581 tgatggttct tatggcatca agggaaatgt ttccgttgtt atcaatgatt tagatagtca
     8641 gtttgatgct gtttactcgt gtggggctcc aggaatgatg aagtatatca atcaaacctt
     8701 tgatgatcac ccaagagcct atttatctct ggaatctcgt atggcttgtg ggatgggagc
     8761 ttgctatgcc tgtgttctaa aagtaccaga aagcgagacg gtcaaccaac gcgtctgtga
     8821 agatggtcct gttttccgca caggaacagt tgtattataa ggagaaaatt atgactacaa
     8881 atcgattaca agtgtctcta cctggtttgg atttgaaaaa tccgattatt ccagcatcag
     8941 gttgttttgg ctttggacaa gagtatgcca agtactatga tttaaacctt ttaggttcta
     9001 ttatgatcaa ggcgacaacc cttgaaccac gttttgggaa cccaactcca agagtagcag
     9061 agacgcctgc tggtatgctc aatgcaattg gcttgcaaaa tcctggttta gaggttgttt
     9121 tggctgaaaa gctaccttgg ctggaaagag aatatccaaa tcttcctatt attgccaatg
     9181 tagctggttt ttcaaaacaa gagtatgcag ctgtttctca tgggatttcc aaggcaacta
     9241 atgtaaaagc tatcgagctc aatatttctt gtcccaatgt tgaccactgt aatcatggac
     9301 ttttgattgg tcaagatcca gatttggctt atgatgtggt gaaagcagct gtggaagcct
     9361 cagaagtgcc agtttatgtc aaattaaccc cgagtgtgac cgatatcgtt actgtcgcaa
     9421 aagctgcaga agatgcggga gcaagtggct tgaccatgat caatactctg gttggaatgc
     9481 gctttgacct caaaaccaga aaaccaatct tggccaatgg aacaggtgga atgtcaggtc
     9541 cagcagtctt tccagtagcc ctcaaactca tccgccaagt agcccaaaca acagacctgc
     9601 ctatcattgg aatgggggga gtggattcgg ctgaagctgc cctagaaatg tatctggctg
     9661 gggcatctgc tatcggagtt ggaacagcta actttaccaa tccttatgcc tgccctgaca
     9721 tcatcgaaaa tttaccaaaa gtcatggata aatacggtat tagcagtctg gaagaactcc
     9781 gtcaggaagt aaaagagtct ctgaggtaaa ctgcaatcaa tctgttcttg attttttatt
     9841 agtttgtaat atgaatttag gagaattttg gtacaataaa ataaataaga acagaggaag
     9901 aaggttaatg aagaaagtaa gatttatttt tttagctctg ctatttttct tagctagtcc
     9961 agagggtgca atggctagtg atggtacttg gcaaggaaaa cagtatctga aagaagatgg
    10021 cagtcaagca gcgaatgagt gggtttttga tactcattat caatcttggt tctatataaa
    10081 agcagatgct aactatgctg aaaatgaatg gctaaagcaa ggtgacgact atttttacct
    10141 caaatctggt ggctatatgg ccaaatcaga atgggtagaa gacaagggag ccttttatta
    10201 tcttgaccaa gatggaaaga tgaaaagaaa tgcttgggta ggaacttcct atgttggtgc
    10261 aacaggtgcc aaagtaatag aagactgggt ctatgattct caatacgatg cttggtttta
    10321 tatcaaagca gatggacagc acgcagagaa agaatggctc caaattaaag ggaaggacta
    10381 ttatttcaaa tccggtggtt atctactaac aagtcagtgg attaatcaag cttatgtgaa
    10441 tgctagtggt gccaaagtac agcaaggttg gctttttgac aaacaatacc aatcttggtt
    10501 ttacataaaa gaaaatggaa actatgctga taaagaatgg attttcgaga atggtcacta
    10561 ttattatcta aaatctggtg gctacatggc agccaatgaa tggatttggg ataaggaatc
    10621 ttggttttat ctcaaatttg atgggaaaat agctgaaaaa gaatgggtct acgattctca
    10681 tagtcaagcc tggtactact tcaaatccgg tggttacatg acagccaatg aatggatttg
    10741 ggataaggaa tcttggtttt acctcaagtc tgatggcaaa atggctgaaa aagaatgggt
    10801 ctacgattct catagtcaag cctggtacta cttcaaatct ggtggttaca tggcgaaaaa
    10861 tgagacagta gatggttatc agcttggaag cgatggtaaa tggcttggag gaaaagctac
    10921 aaatgaaaat gctgcttact atcaagtagt gcctgttaca gccaatgttt atgattcaga
    10981 tggtgaaaag ctttcctata tatcgcaagg tagtgtcgta tggctagata aggatagaaa
    11041 aagtgatgac aagcgcttgg ctattactat ttctggtttg tcaggctata tgaaaacaga
    11101 agatttacaa gcgctagatg ctagtaagga ctttatccct tattatgaga gtgatggcca
    11161 ccgtttttat cactatgtgg ctcagaatgc tagtatccca gtagcttctc atctttctga
    11221 tatggaagta ggcaagaaat attattcggc agatggcctg cattttgatg gttttaagct
    11281 tgagaatccc ttccttttca aagatttaac agaggctaca aactacagtg ctgaagaatt
    11341 ggataaggta tttagtttgc taaacattaa caatagcctt ttggagaaca agggcgctac
    11401 ttttaaggaa gccgaagaac attaccatat caatgctctt tatctccttg cccatagtgc
    11461 cctagaaagt aactggggaa gaagtaaaat tgccaaagat aagaataatt tctttggcat
    11521 tacagcctat gatacgaccc cttacctttc tgctaagaca tttgatgatg tggataaggg
    11581 aattttaggt gcaaccaagt ggattaagga aaattatatc gataggggaa gaactttcct
    11641 tggaaacaag gcttctggta tgaatgtgga atatgcttca gacccttatt ggggcgaaaa
    11701 aattgctagt gtgatgatga aaatcaatga gaagctaggt ggcaaagatt agtactataa
    11761 gtgaatatga tttgagtgaa tagtaagtta aaaatcctga tttcaagtaa aatcaggatt
    11821 ttttcatgga tgcaattttt ttggagtctg gtgtgacgcg gagggtcttt tgtcctgtgt
    11881 aagtgacaaa gccgggtttt ccaccagttg gtttattgag ttttttgact tcaatcatat
    11941 ctacctgcac cagattcgac aggcgccctt gagagaagta ggcagctaac tctgctgcgt
    12001 ctgtcttgac tgcatcagat gggtcaagat ttcctgagat gacaacatgg cttccaggaa
    12061 tgtccttagc atggaaccaa agttcctcct tgcgggccat tttaaaggtc aattcctcat
    12121 tttgaagatt gtttcgtccg acatagatga tggttttgcc atcgcttgct agatattgtt
    12181 ctagtttttt gcgtttctgg attttctccc gttgtcttct gcggataaaa cctgtttgaa
    12241 tcaattcttc acggatttca gcgatttctt ccagtccagc ttggttgagg acggtttcta
    12301 cactttccag atagagaata gtggctttgg tttcttcaat caaatcagtc aagtatttga
    12361 cagcttcttt gagtttctga taccgtttaa aatagcgttg ggcattctgg ttgggagtca
    12421 gagccttatc aagcgcaatc atgataggtt ggttggtata gtagttgtct aggataacct
    12481 ggtcttggtc gttaggcact tggtggagga aggttgtcag caattctcct ttttgacgaa
    12541 attcttcagc gttgtctgtc gccagtaact ctttttcctg ttttttgagt ttgtgtcggt
    12601 ttttctgaag ttcattttca acacgacgaa tcagttcact ggcctgctgt ttgacgcggt
    12661 cgcgctcagc cttatcctta tagtaggtgt ccaacaaatc agaaagattt gcaagaggct
    12721 ctcccacctg atttgcaaaa ggaactggac tgaaggaagt ctcagtcaag catggcttgg
    12781 tttcttgatt gaaaaaattt cggaaagcgg aaagtttttc actaaccagt atcctttcca
    12841 attcatttgc cgtatcgcgt cccagacctt gaaagaggct ttgaagattt tttgctgtta
    12901 gttcttgggt ttgcaggatt tcaaagagct tttcatcctt gatagtaaaa ggattgagag
    12961 attttgtact tggcggagcg atataggtcg atcctggaag taaggtgcgg tagctatttt
    13021 gtgaaaagcc gacgtgtttg ataacttcga ggattttatg actgctttta tcgaccagta
    13081 gaatattact gtgtttcccc ataatttcga taatcaaggt agcctggata tggtctccaa
    13141 tctcgttttt attggaaact gtaatttcca caatacggtc attttccact tgctcaatcg
    13201 actcaatcag ggccccctgc aaatactttc tcaaaaccat gataaaggta gaaggttggg
    13261 ctggattttc aaaagtcgtt tgggtcagct gaatgcgtcc aaaaactgga tgggcagaaa
    13321 ggagcaggcg atggctttgg cgattgctgc ggatttgcaa gaccaactct tgttcaaaag
    13381 gctgattgat tttctggatg cgaccattca ctaattcgct tcgcaattcc tcaactatgt
    13441 ggtgtaaaaa aaatccgtca aatgacatcg ttctctcctt gtgattgtat tccatagtat
    13501 tatatcaaaa aggtagaata aaatcatgga aatgtggtat aataaagcca agtaaagaga
    13561 aacgagaagc acatgtatat tgaaatggta gatgaaactg gtcaagtttc aaaagaaatg
    13621 ttgcaacaaa cccaagaaat tttggaattt gcagcccaaa aattaggaaa agaagacaag
    13681 gagatggcag tcacttttgt gaccaatgag cgtagtcatg aacttaatct ggggtaccgt
    13741 gacaccgacc gtccgacaga tgtcatcagc cttgagtata aaccagaatt ggaaattgcc
    13801 tttgacgaag aggatttgct tgaaaatcca gaattggcag agatgatgtc tgagtttgat
    13861 gcctatattg gggaattgtt catctctatc gataaggctc atgagcaggc cgaagaatat
    13921 ggtcacagct ttgagcgtga gatgggcttc ttggcagtac acggcttttt acatattaac
    13981 ggctatgatc actatactcc ggaagaagaa gcggagatgt tcggtttaca agaagaaatt
    14041 ttgacagcct atggactcac aagacaataa acgaaaatgg aaaaatcgtg acctgatatc
    14101 cagtttagaa tttgccatca cagggatttt tactgctatc aaggaagaac gcaatatgcg
    14161 aaaacatgca gtgacggctc tagtggtcat ccttgcaggt tttggttttc aggtgtcacg
    14221 aatcgaatgg ctctttctcc tattgagcat tttcttggtg gtagcctttg aaattatcaa
    14281 ttctgctatc gaaaatgtgg tggatttggc cagtcactat cacttttcca tgctggctaa
    14341 aaatgccaag gatatggcgg ctggcgcggt attagtggtt tctctttttg cagccttaac
    14401 aggcgcattg atttttctcc cacgaatctg ggatttatta ttttaaacag taagaggaaa
    14461 ttatgacttt taaatcaggc tttgtagcca ttttaggacg tcccaatgtt gggaagtcaa
    14521 cctttttaaa tcacgttatg gggcaaaaga ttgccatcat gagtgacaag gcgcagacaa
    14581 cgcgcaataa aatcatggga atttacacga ctgataagga gcaaattgtc tttatcgaca
    14641 caccagggat tcacaaacct aaaacagctc tcggagattt catggttgag tctgcctaca
    14701 gtacccttcg cgaagtggac actgttcttt tcatggtgcc tgctgatgaa gcgcgtggta
    14761 agggggacga tatgattatc gagcgtctca aggctgccaa ggttcctgtg attttggtgg
    14821 tgaataaaat cgataaggtc catccagacc agctcttgtc tcagattgat gacttccgta
    14881 atcaaatgga ctttaaggaa attgttccaa tctcagccct tcagggaaat aacgtgtctc
    14941 gtctagtgga tattttgagt gaaaatctgg atgaaggttt tcaatatttc ccgtctgatc
    15001 aaatcacaga ccatccagaa cgtttcttag tttcagaaat ggttcgcgag aaagtcttgc
    15061 acctaactcg tgaagagatt ccgcattctg tagcagtagt tgttgactct atgaaacggg
    15121 acgaagagac agacaaggtt cacatccgtg caaccatcat ggtcgagcgc gatagccaaa
    15181 aagggattat catcggtaaa ggtggcgcta tgcttaagaa aatcggtagc atggcccgtc
    15241 gtgatatcga actcatgcta ggagacaagg tcttcctaga aacctgggtc aaggtcaaga
    15301 aaaactggcg cgataaaaag ctagatttgg ctgactttgg ctataatgaa agagaatact
    15361 aagtagaggt gggctcatgc ctgcttcttg tttttacaga aggaggactt atgcctgaat
    15421 tacctgaggt tgaaaccgtt tgtcgttgct tagaaaaatt gattatagga aagaagattt
    15481 cgagtataga aattcgctac cccaagatga ttaagacgga tttggaagag tttcaaaggg
    15541 aattgcctag tcagattatc gagtcaatgg gacgtcgtgg aaaatatttg cttttttatc
    15601 tgacagacaa ggttttgatt tcccatttgc ggatggaggg caagtatttt tactatccag
    15661 accaaggacc tgaacgcaag catgcccatg ttttctttca ttttgaagat ggtggcacgc
    15721 ttgtttatga ggatgttcgc aagtttggaa ccatggaact cttggtgcct gaccttttag
    15781 acgcctactt tatttctaaa aaattaggtc ctgaaccaag cgaacaagac tttgatttac
    15841 aggtctttca atctgccctt gccaagtcca aaaagcctat caaatcccat ctcctagacc
    15901 agaccttggt agctggactt ggcaatatct atgtggatga ggttctctgg cgagctcagg
    15961 ttcatccagc tagatcttcc cagactttga cagcagaaga agcgacagct attcatgacc
    16021 aaaccattgc tgttttgagc caggctgttg aaaaaggcgg ttccaccatt cggacctata
    16081 ccaatgcctt tggggaagat ggaagcatgc aggattttca tcaggtctat gataagactg
    16141 gtcaaggatg tgtacgctgt ggtaccatca ttgagaaaat tcaactaggt ggacgtggaa
    16201 cccacttttg tccaaactgt caaaggaggg actgatggga aaaatcatcg gaatcactgg
    16261 gggaattgcc tctggtaagt caactgtgac aaattttcta agacagcaag gctttcaagt
    16321 agtggatgcc gacgcagtcg tccaccaact acagaaacct ggtggtcgtc tgtttgaggc
    16381 tctagtacag cacttttggc aagaaatcat tcttgaaaac ggagaactca atcgccctct
    16441 cctagctagt ctcatctttt caaatcctga tgaacgagaa tggtctaagc aaattcaagg
    16501 ggagattatc cgtgaggaac tggctacttt gagagaacag ttggctcaga cagaagagat
    16561 tttcttcatg gatattcccc tactttttga gcaggactac agcgattggt ttgctgagac
    16621 ttggttggtc tatgtggacc gagatgccca agtagaacgc ttaatgaaaa gggaccagtt
    16681 gtccaaagat gaagctgagt ctcgtctggc agcccagtgg cctttagaaa aaaagaaaga
    16741 tttggccagc caggttcttg ataataatgg caatcagaac cagcttctta atcaagtgca
    16801 tatccttctt gagggaggta ggcaagatga cagagattaa ctggaaggat aatctgcgca
    16861 ttgcctggtt tggtaatttt ctgacaggag ccagtatttc tttggttgta ccttttatgc
    16921 ccatcttcgt ggaaaatcta ggtgtaggga gtgagcaagt cgctttttat gcaggcttag
    16981 caatttctgt ctctgctatt tccgcggcgc tcttttctcc tatttggggt attcttgctg
    17041 acaaatacgg ccgaaaaccc atgatgattc gggcaggtct tgctatgact atcactatgg
    17101 gaggcttggc ctttgtccca aatatctatt ggttaatctt tcttcgttta ctaaacggtg
    17161 tatttgcagg ttttgttcct aatgcaacgg cactgatagc cagtcaggtt ccaaaggaga
    17221 aatcaggctc tgccttaggt actttgtcta caggcgtagt tgcaggtact ctaactggtc
    17281 cctttattgg tggctttatc gcagaattat ttggcattcg tacagttttc ttactggttg
    17341 gtagttttct atttttagct gctattttga ctatttgctt tatcaaggaa gattttcaac
    17401 cagtagccaa ggaaaaggct attccaacaa aggaattatt tacctcggtt aaatatccct
    17461 atcttttgct caatctcttt ttaaccagtt ttgtcatcca attttcagct caatcgattg
    17521 gccctatttt ggctctttat gtacgcgatt tagggcagac agagaatctt ctttttgtct
    17581 ctggtttgat tgtgtccagt atgggctttt ccagcatgat gagtgcagga gtcatgggca
    17641 agctaggtga caaggtgggc aatcatcgtc tcttggttgt cgcccagttt tattcagtca
    17701 tcatctatct cctctgtgcc aatgcctcta gcccccttca actaggactc tatcgtttcc
    17761 tctttggatt gggaaccggt gccttgattc ccggggttaa tgccctactc agcaaaatga
    17821 ctcccaaagc cggcatttcg agggtctttg ccttcaatca ggtattcttt tatctgggag
    17881 gtgttgttgg tcccatggca ggttctgcag tagcaggtca atttggctac catgctgtct
    17941 tttatgcgac gagcctttgt gttgccttta gttgtctctt taacctgatt caatttcgaa
    18001 cattattaaa agtaaaggaa atctagtgcg agtaaaaatt aatctcaaat gctcctcttg
    18061 tggcagtatc aattacctaa ccagtaaaaa ttcaaaaacc catccagaca agattgaggt
    18121 tttaaagtat tgtcccaagg aaagaaaagt aaccctacat cttgaatcta agtagatttt
    18181 atggtaaaat aatagggatt ttaaggagtt tgatatgtat aacctattat taaccatttt
    18241 attagtatta tctgttgtga ttgtgattgc aattttcatg caaccaacca aaaaccaatc
    18301 cagcaatgta tttgatgcca gttcaggtga tttgtttgaa cgtagtaaag ttcgcggttt
    18361 tgaagctgta atgcagcgtt tgacagggat tttagtcttt ttctggctag ccattgcctt
    18421 agcattgacg gtattatcaa gtagataaga aaataatggg caggactagg tctttgcctc
    18481 tttttatttt taaaggatgt ttgagaaggt tttacagtaa aagaaaatta aaaaatctag
    18541 aaagaaaata tgaaagatag aataaaagaa tatttacaag acaagggaaa ggtgactgtt
    18601 aatgatttgg ctcaggcttt gggaaaagac agttccaagg attttcgtga gttgattaaa
    18661 accttgtcct taatggaaag aaagcaccaa attcgttttg aagaagatgg tagtctgaca
    18721 ttagaaatta agaaaaaaca tgagattacc ctcaagggga tttttcatgc ccataaaaat
    18781 ggctttggct ttgttagtct ggaaggcgag gaggacgacc tttttgtagg gaaaaatgat
    18841 gtcaactatg ctattgatgg tgataccgtc gaggtagtga ttaagaaagt cgctgaccgc
    18901 aataagggaa cagcagcaga agccaaaatt attgatatcc tagaacacag tttgacaaca
    18961 gttgtcgggc aaatcgttct ggatcaggaa aaacctaagt atgctggcta tattcgttca
    19021 aaaaatcaga aaatcagtca accgatttat gttaagaaac cagccctaaa attagaagga
    19081 acagaagttc tcaaagtctt tatcgataaa tacccaagca agaaacatga tttctttgtc
    19141 gcgagtgttc tcgatgtagt gggacactca acggatgtcg gaattgatgt tcttgaggtc
    19201 ttggaatcaa tggacattgt atccgagttt ccagaagctg ttgttaagga agcagaaagt
    19261 gtgcctgatg ctccgtctca aaaggatatg gaaggtcgtc tggatctaag agatgaaatt
    19321 acctttacca ttgacggtgc ggatgccaag gacttggacg atgcagtgca tatcaaggct
    19381 ctgaaaaatg gcaatctgga gcttggggtt cacatcgcag atgtttctta ttatgtgacc
    19441 gaggggtctg cccttgacaa ggaagccctt aaccgtgcga cttctgttta cgtgacagac
    19501 cgagtggtgc caatgcttcc agaacgacta tcaaatggca tctgctctct caatccccaa
    19561 gttgaccgcc tgacccagtc tgctattatg gagattgata aacatggtcg tgtggtcaac
    19621 tataccatta cacaaacagt tatcaagacc agttttcgta tgacctatag cgatgtcaat
    19681 gatatcctag ctggcgatga agaaaagaga aaagaatatc ataaaattgt atcaagtatc
    19741 gaactcatgg ccaagcttca tgaaacttta gaaaacatgc gtgtgaaacg tggagctctc
    19801 aattttgata ccaatgaagc gaagatttta gtggataaac aaggtaagcc tgttgatatc
    19861 gttcttcggc agcgtggtat tgccgagcgg atgattgagt cttttatgtt gatggctaat
    19921 gaaacagttg ccgaacattt cagcaagttg gatttgcctt ttatctatcg aattcacgag
    19981 gagcctaagg ctgaaaaggt tcagaagttt attgattatg cttcgagttt tggcttgcgc
    20041 atttatggaa ctgccagtga gattagtcag gaggcacttc aagacatcat gcgtgctgtt
    20101 gagggagaac cttatgcaga tgtattgtcc atgatgcttc ttcgctctat gcagcaggct
    20161 cgttattcgg agcacaatca cggccactat ggactagctg ctaactatta tactcacttt
    20221 accagtccaa ttcgtcgtta tccagacctt cttgttcacc gtatgattcg ggattacggc
    20281 cgttctaagg aaatagcaga gcattttgaa caagtgattc cagagattgc gacccagtct
    20341 tccaaccgtg aacgtcgtgc catagaagct gagcgtgaag tcgaagccat gaaaaaggct
    20401 gagtatatgg aagaatacgt gggtgaagag tatgatgcag ttgtatcaag tattgtcaaa
    20461 ttcggtctct ttgtcgaatt gccaaacaca gttgaaggct tgattcacat cactaatcta
    20521 cctgaatttt atcatttcaa tgagcgtgat ttgactcttc gtggagaaaa atcaggtatc
    20581 actttccgag tgggtcagca gatccgtatc cgtgttgaaa gagcggataa aatgactgga
    20641 gagattgatt tttcattcgt acctagtgag tttgatgtga ttgaaaaagg cttgaaacag
    20701 tctagtcata gtggcagagg gcgtggttca aatcgtcgtt cggataagaa ggaagacaag
    20761 agaaaatcag gacgctcaaa tgataagcgt aagcattcac aaaaagacaa gaagaaaaaa
    20821 ggaaagaaac ctttttacaa ggaagtagct aagaaaggag ccaagcatgg caaagggcga
    20881 gggaaaggtc gtcgcacaaa ataaaaaggc acgccacgac tatacaatcg tagatacgct
    20941 agaggcaggg atggtcctga ctggaactga aatcaagagt gtacgagctg ctcgaattaa
    21001 tctcaaggat ggctttgctc aagtgaaaaa tggagaagtt tggctgagca atgttcatat
    21061 cgcgccttac gaagagggca atatctggaa ccaggaacca gaacgtcgtc gtaaactcct
    21121 gctccataaa aagcaaattc aaaaattgga acaagagacc aaagggacag gaatgacctt
    21181 agttcccctt aaggtctata taaaagatgg ctacgctaag cttcttttag gacttgccaa
    21241 agggaagcat gactatgaca aacgggagtc tatcaaacgt cgtgagcaaa atcgagatat
    21301 cgcgcgtgtg atgaaagctg ttaatcagcg ataaaaagag gaattgaaaa tggaaaaatt
    21361 agttgcctat aaacgcatgc ctttgtggaa taaacaaaca atgcctgaag ctgttcagca
    21421 aaagcacaat acaaaagttg ggacttgggg gaaaattact gtcttgaagg gagctctcaa
    21481 gtttattgaa ttgacagaag aaggggaagt tctagctgaa cacctctttg aagcaggggc
    21541 agacaatcca atggcccaac ctcaagcctg gcaccgagtg gaagctgcca cagatgatgt
    21601 ggaatggtac ttggaatttt attgtaaacc tgaggattat tttgctaaaa aatacaatac
    21661 caatcctgtt cattcagagg tcctagaggc catgcagaca gtgaaacaag ggaaagcttt
    21721 ggatttgggt tgtggtcagg ggcgtaattc tctttttcta gcccagcaag attttgatgt
    21781 gacggctgta gatcaaaatg gactagctct tgaaatcttg caaagcattg tggagcagga
    21841 agatttggac atgcctgttg gcctttacga tatcaattca gctagcattg aacaagaata
    21901 tgattttatc gtttcaacag ttgttctcat gtttctacaa gcggaccgca ttccagctat
    21961 tattcaaaat atgcaggaga aaaccagtgt tggtggttac aaccttatcg tttgtgccat
    22021 ggacacggag gattatcctt gctcggttaa tttcccattc acctttaaag aaggagaact
    22081 ggcagactat tacaaggatt gggaattggt taagtacaat gaaaatccag gccatttgca
    22141 ccgtcgcgat gagaatggca atcgtattca actacgcttt gcgaccttac tagctaagaa
    22201 aatcaagtaa acacacatga agattaggaa ttttcctgat cttttttctt ttttacgaat
    22261 gatatagaaa aggagggaat tcatgtttgt tgcgagagat gctaggggag aattggtaaa
    22321 tgtgttagag gataaacttg agaagcaagc atacacctgc ccagcttgtg gaggccagct
    22381 ccatttgcgt caaggaccaa gtgtacggac gcattttgcc cataaatcct taaaagactg
    22441 tgattttttc tttgaaaatg aaagtccaga acacctggcc aataaggaat ccctctatca
    22501 ctggttgaaa aaagagacaa aggttcaatt agagtacccg ctttcagaac ttaaacagat
    22561 tgcggatgta tttgtaaatg gcaatctagc tctagaagtt cagtgtagtc ccttgcctca
    22621 gaaagtcctt aaagagcgaa gtgagggata tcgtagtcag ggttaccaag tactgtggtt
    22681 gctgggtcaa aaactgtggc tcaaggagcg tttgactcgt ctacagcaag gttttcttta
    22741 tttcagtcaa aacatgggct tttatgtttg ggaattagac aaggaaaaac aagttttaag
    22801 actcaaatac ctgatttacc aggatctccg cggtaaactc cattatcaaa tcaaggaatt
    22861 ttcctatggt caaggtagtt tattggaaat attgcgtctt ccctataaga aacaaaaaat
    22921 atctcatttt acagtttctg aggacaagga catctgtcgc tatatccggc aacaacttta
    22981 ttatcaaaat ctcttttgga tgaaagaaca agcagaagcc tatcaaaagg gagaaaatat
    23041 cctgacttat ggactgaaag aatggtatcc acaaattcga ccaatagtgg gcaaattttt
    23101 ccagattgaa caagacttga ctagctatta tcagcacttt tatacctatt accaaaaaaa
    23161 tcctcaaaat gattggcaaa agctttatcc accagccttt tatcagcaat atttcttgaa
    23221 aaatatggta gaatagaaag gatggaggaa tctaatggta ttacaaagaa atgaaataaa
    23281 tgaaaaagat acatgggatc tatcaacgat ctacccaact gaccaggctt gggaagaagt
    23341 cttaaaagat ttaacagaac aattggagac agtagcccag tatgaaggcc atctcttgga
    23401 tagtgcggat aacctactag aaatcactga attttctctt gaaatggaac gccagatgga
    23461 gaagctttac gtttatgctc atatgaagaa tgaccaggat acacgtgaag ctaagtatca
    23521 agagtactat gccaaggcca tgacattcta cagccagtta gaccaagcct tttcattcta
    23581 tgagcctgaa tttatggaga ttagcgaaaa gcagtatgct gactttttag aagctcaacc
    23641 aaagctgcag gtttatcaac actattttga caagctcttg caaggcaagg atcacgttct
    23701 ctcacaacgt gaagaagaat tattggctgg agctggagaa atctttggtt cagcaagtga
    23761 aaccttcgct atcttggaca atgcggatat tgtgttccct tatgtcctag acgatgatgg
    23821 taaagaagtt cagctatctc atgggattta cacacgtttg atggagtcta aaaaacgtga
    23881 ggttcgccgt ggtgcctatc aagctcttta tgcgacttac gaacaattcc aacacaccta
    23941 tgccaaaacc ttgcaaacca atgttaaggt gcaaaattac cgtgctaaag ttcgtaacta
    24001 caagagtgct cgtcatgcag ccctcgcagc gaattttgtt ccagaaagtg tttatgacaa
    24061 tttggtagca gcagttcgca agcatttgcc actcttacat cgctatcttg agcttcgttc
    24121 aaaaatcttg gggatttcag atctcaagat gtacgatgtc tacacaccgc tttcatctgt
    24181 tgaatacagt tttacctacc aagaagcctt gaaaaaagca gaagatgctt tggcagtctt
    24241 gggtgaggat tacttgagcc gtgttaaacg tgccttcagc gagcgttgga ttgatgttta
    24301 cgaaaatcaa ggcaagcgtt caggtgccta ctctggtggt tcttacgata ccaatgcctt
    24361 tatgcttctc aactggcagg acaatctgga caatctcttt actcttgttc atgaaacagg
    24421 tcatagtatg cattcaagct atactcgtga aactcagcct tatgtttacg gagattactc
    24481 tatctttttg gctgagattg cctcaactac caatgaaaat atcttgacgg agaaattatt
    24541 ggaagaagtg gaagacgacg caacacgctt tgctattctc aataacttcc tagatggttt
    24601 ccgtggaaca gttttccgcc aaactcaatt tgctgagttt gaacacgcca ttcaccaagc
    24661 agatcaaaat ggggaggtct tgacaagcga tttcctaaat aaactctacg cagacttgaa
    24721 ccaagagtat tatggtttga gtaaggaaga caatcctgaa atccaatacg agtgggctcg
    24781 cattccacac ttctactata actactatgt atatcaatat tcaactggct ttgcggccgc
    24841 ctcagccttg gctgaaaaaa ttgtccatgg tagtcaagaa gaccgtgacc gctatatcga
    24901 ctacctcaag gcaggtaagt cggactatcc acttaatgtc atgagaaaag ctggtgttga
    24961 tatggagaag gaagactacc tcaacgatgc ctttgcagtc tttgaacgcc gtttaaatga
    25021 gtttgaagcc cttgttgaaa aattaggatt ggcataaaat ggttgaatcg tatagtaaga
    25081 atgctaacca taacatgcgt cgtcctgtcg tcaaagaaga aattgtagac ttgatgcgtc
    25141 agcgtcaaaa gcaggtcaca ggtttcttga aagaattgga aaactttgcc cgcaaggaaa
    25201 atattcctat tattccccat gaaacggttg cttatttccg ttttcttatg gaaaccatgc
    25261 agcctaaaaa tattctggaa attgggacgg ctatcggttt ttcagctctc ttgatggctg
    25321 aacatgcgcc aaatgctaag attacaacta ttgatcgtaa tccagaaatg attggttttg
    25381 ccaaggaaaa ttttgcccag tttgacagtc gcaagcaaat cactctccta gagggagatg
    25441 cggtggatgt cttatctaca ctgacagagt cttatgattt cgtctttatg gattctgcca
    25501 agtctaaata catcgtcttt ctgccagaaa tcctcaaaca tttggaagtt ggtggtgtgg
    25561 ttgtcttgga tgatattttt caaggtggtg atgttgccaa ggatattatg gaagtccgtc
    25621 gtggtcagcg aaccatttat cgaggccttc aaaaattatt tgatgcaacc ttagacaatc
    25681 cagaactcac cgcaacatta gtgcctttag gagatggtat tctcatgctt cgtaaaaatg
    25741 tagcagatgt tcaactgtct gaaagcgaat gattttcaga aaaatttaag aaaaaatagt
    25801 aaaatagata gagtaacact tatctcaaag gagtagacat gaagaaaaaa ttattggcag
    25861 gtgccatcac actattatca gtagcaactt tagcagcttg ttcgaaaggg tcagaagggg
    25921 cagaccttat cagcatgaaa ggggatgtca tcacagaaca tcaattttat gagcaagtga
    25981 aaaacaaccc ttcagcccaa caagtcttgt taaatatgac catccaaaaa gtttttaaaa
    26041 aacaatatgg ctcagagctt gatgataaag aggttgatga tactattgcc gaagaaaaaa
    26101 aacaatatgg cgaaaactac caacgtgtct tgtcacaagc aggtatgact cttgaaacac
    26161 gtaaagctca aattcgtaca agtaaattag ttgagttggc agttaagaag gtagcagaag
    26221 ctgaattgac agatgaagcc tataagaaag cctttgatga gtacactcca gatgtaacgg
    26281 ctcaaatcat ccgtcttaat aatgaagata aggccaaaga agttctcgaa aaagccaagg
    26341 cagaaggtgc tgattttgct caattagcca aagataattc aactgatgaa aaaacaaaag
    26401 aaaatggtgg agaaattacc tttgattctg cttcaacaga agtacctgag caagtcaaaa
    26461 aagccgcttt cgctttagat gtggatggtg tttctgatgt gattacagca actggcacac
    26521 aagcctacag tagccaatat tacattgtaa aactcactaa gaaaacagaa aaatcatcta
    26581 atattgatga ctacaaagaa aaattaaaaa ctgttatctt gactcaaaaa caaaatgatt
    26641 caacatttgt tcaaagcatt atcggaaaag aattgcaagc agccaatatc aaggttaagg
    26701 accaagcctt ccaaaatatc tttacccaat atatcggtgg tggagattca agctcaagca
    26761 gtagtacatc aaacgaatag tccaaatcaa tgagtcaggg aaaaaaactc gacttcagga
    26821 aaaaatgaag caaacattcc cacaataaaa cgcatagtac aaggtttgta ctgaccccaa
    26881 aagttagaca attaatttat ctgaaggatt tagttctgta ttgcacaggg ctaagtcctt
    26941 ttagttttac cttaattctc ttattgttgt aataatcaat atagtctata atggcttgtt
    27001 ccaattgatt aagtgattta aatgttttct catagccata aaacatttcg gattttaaaa
    27061 tgccaaagaa agattccatc ctaccgttgt cttggctgtt tcctttgcgt gacatagatg
    27121 cttgaattcc cttactctct aggaagcgat gataagaatc gtgttggtat tgccagcctt
    27181 ggtcactatg gagaatcgta ttctcgtagt gcttctcttt gaatgcctgt tccaaca
//
LOCUS       DAVKUR010000024        25807 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKUR010000024 DAVKUR010000000
VERSION     DAVKUR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.024"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            343..1386
                     /locus_tag="VW749_001171"
     CDS             343..1386
                     /locus_tag="VW749_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0175214.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIIARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1553..3640
                     /gene="topA"
                     /locus_tag="VW749_001172"
     CDS             1553..3640
                     /gene="topA"
                     /locus_tag="VW749_001172"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0175215.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEENIK"
     gene            3746..4105
                     /locus_tag="VW749_001173"
     CDS             3746..4105
                     /locus_tag="VW749_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0175216.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4198..4830
                     /locus_tag="VW749_001174"
     CDS             4198..4830
                     /locus_tag="VW749_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0175217.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGVLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQVGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4874..5530
                     /locus_tag="VW749_001175"
     CDS             4874..5530
                     /locus_tag="VW749_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0175218.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5549..6169
                     /locus_tag="VW749_001176"
                     /pseudo
     CDS             5549..6169
                     /locus_tag="VW749_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            6197..6631
                     /locus_tag="VW749_001177"
     CDS             6197..6631
                     /locus_tag="VW749_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV0175219.1"
                     /translation="MVAGSMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6643..7680
                     /gene="leuB"
                     /locus_tag="VW749_001178"
     CDS             6643..7680
                     /gene="leuB"
                     /locus_tag="VW749_001178"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0175220.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLATIGSPQYDGAVVRPEQGLMTLRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVSMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7677..7946
                     /locus_tag="VW749_001179"
     CDS             7677..7946
                     /locus_tag="VW749_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0175221.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7950..8309
                     /gene="leuD"
                     /locus_tag="VW749_001180"
     CDS             7950..8309
                     /gene="leuD"
                     /locus_tag="VW749_001180"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0175222.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8528..8671
                     /locus_tag="VW749_001181"
     CDS             8528..8671
                     /locus_tag="VW749_001181"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175223.1"
                     /translation="MTSDKAGLERKFAAKEGKRNKPGVVLCGSMDELCALAQLNPKIE
                     AFY"
     gene            8690..8944
                     /locus_tag="VW749_001182"
     CDS             8690..8944
                     /locus_tag="VW749_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175224.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            8934..9095
                     /locus_tag="VW749_001183"
     CDS             8934..9095
                     /locus_tag="VW749_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175225.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNL
                     WDYRQVEYY"
     gene            9258..9621
                     /locus_tag="VW749_001184"
                     /pseudo
     CDS             9258..9621
                     /locus_tag="VW749_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828316.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
     gene            9597..9911
                     /locus_tag="VW749_001185"
     CDS             9597..9911
                     /locus_tag="VW749_001185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175226.1"
                     /translation="MDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAM
                     VTKLLCIYSEGDSFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVPKLILSWSH
                     RN"
     gene            9971..11188
                     /locus_tag="VW749_001186"
     CDS             9971..11188
                     /locus_tag="VW749_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0175227.1"
                     /translation="MDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTD
                     GNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGG
                     QDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYE
                     LYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEIS
                     KIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFD
                     FAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPS
                     YFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVA
                     DDNEGDENDDADY"
     gene            11175..12491
                     /locus_tag="VW749_001187"
     CDS             11175..12491
                     /locus_tag="VW749_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0175228.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12666..13652
                     /locus_tag="VW749_001188"
     CDS             12666..13652
                     /locus_tag="VW749_001188"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0175229.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13716..13787
                     /locus_tag="VW749_001189"
     tRNA            13716..13787
                     /locus_tag="VW749_001189"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13749..13751,aa:Arg,seq:ccg)
     gene            13970..14668
                     /locus_tag="VW749_001190"
     CDS             13970..14668
                     /locus_tag="VW749_001190"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0175230.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14659..18198
                     /gene="smc"
                     /locus_tag="VW749_001191"
     CDS             14659..18198
                     /gene="smc"
                     /locus_tag="VW749_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0175231.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLEIILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18195..18989
                     /locus_tag="VW749_001192"
     CDS             18195..18989
                     /locus_tag="VW749_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0175232.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            18989..19807
                     /locus_tag="VW749_001193"
     CDS             18989..19807
                     /locus_tag="VW749_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0175233.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19811..21100
                     /gene="ftsY"
                     /locus_tag="VW749_001194"
     CDS             19811..21100
                     /gene="ftsY"
                     /locus_tag="VW749_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0175234.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21146..22633)
                     /locus_tag="VW749_001195"
     CDS             complement(21146..22633)
                     /locus_tag="VW749_001195"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0175235.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(22782..23522)
                     /locus_tag="VW749_001196"
     CDS             complement(22782..23522)
                     /locus_tag="VW749_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0175236.1"
                     /translation="MVKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23522..25687)
                     /locus_tag="VW749_001197"
     CDS             complement(23522..25687)
                     /locus_tag="VW749_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0175237.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT         8035 a         4569 c         5716 g         7487 t
ORIGIN      
        1 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
       61 tggttattat aaaaaatggt ctgaaataga tgatgatact tttcgaaaat ctttttacat
      121 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      181 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catctgagtc aggatattat
      241 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      301 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      361 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      421 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      481 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      541 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      601 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      661 gctagttcgg agattattgc tagaacctct ccgactattt gggatgttct cattgctttt
      721 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      781 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      841 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
      901 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
      961 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1021 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1081 aagaaattta tatcagagca gtttcagggg cataatattt tgaaaaaaac ctattctaaa
     1141 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1201 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1261 ttgtctgatt cagaacaact tagtaaggaa gaactggtgg agtatttctt ccagtatatc
     1321 aaggataagg aagcaaaaga aaaggaaaaa gctaataagt tttatacaga gtctgaggag
     1381 caataatttc ttgagaatag ctggtttttc tcgtgagtct tctatgtata tcaaaggaag
     1441 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     1501 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     1561 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     1621 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     1681 gcatatccgt gatttgaaga aatccagtat gtccgttgat attgaaaata attatgaacc
     1741 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     1801 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     1861 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     1921 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     1981 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     2041 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     2101 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     2161 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     2221 tggtaaaaag atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac
     2281 tagtaaagac ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt
     2341 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     2401 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     2461 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     2521 ggcggcaagc ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt
     2581 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa
     2641 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     2701 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     2761 attgtctcaa aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     2821 tcttgccatt tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga
     2881 tgtggtcaaa caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     2941 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     3001 cgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     3061 tgaaccgaca gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat
     3121 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     3181 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     3241 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     3301 agtgtgtggc agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     3361 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     3421 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tcttctatgg
     3481 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     3541 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     3601 ttgtagcaaa ggcgactacg aggaagaaaa tattaaataa gaggaggggc ccgaaagtaa
     3661 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     3721 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     3781 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     3841 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     3901 caagctctat caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg
     3961 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     4021 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcacct attatctctt
     4081 caaggtcatt ccagacaaag aataattaaa acagtagtta tttcccttga taaaattgaa
     4141 agcatattca taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
     4201 atttacgaat tttgtgctga aaatgtgacc ttgcttgaaa aagcgatgca ggctggagct
     4261 cgtcggattg aactctgtga taatctagca gttggtggga caacccccag ctatggagtg
     4321 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
     4381 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
     4441 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagttttaac tgctgataaa
     4501 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
     4561 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
     4621 agtcaagtcg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
     4681 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
     4741 ccaggtgggg ggattgacct tgacaaccgt caaaccttta tcgaccaggt gggggtaaca
     4801 cagttgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
     4861 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
     4921 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
     4981 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
     5041 agagactggc gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
     5101 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
     5161 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
     5221 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
     5281 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
     5341 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tactttcaca
     5401 aaaggggatt tatccagcct ttcatatgag caagcgctac tggattagtg tgtcccttga
     5461 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
     5521 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
     5581 gaagaaattt tcagaaaata taggatttac cacactagag gaatatggtg catcttcaaa
     5641 tacctgattg agaatgtcaa gacggatcgt cagatcatct attcgcctca ctgtcatgat
     5701 gacctcggaa tggcagtggc aaatagcctt gctgctgtca agaatggtgc aggacgtgtt
     5761 gaagggacta tcaatggtat tagggagcga gctggaaatg ctgctttgga agaaattgca
     5821 gtggctctca atattcgcca agattactac caagtagaaa ccagtattgt cctaaatgag
     5881 accatcaata cgtcagaaat ggtttctcgc ttctctggta ttccagttcc taaaaacaaa
     5941 gccgtcgttg gtggcaatac cttctcccac gaatctggta ttcaccaaga tggagtcctt
     6001 aaaaatcctc tcacttatga gatcatcaca cctgaattgg ttggtgttaa gattccgctt
     6061 gggtcgccat gcttttgttg agaaactgag agaattggcc ctagatttta cagaagagga
     6121 tatcaaacca ctctttgcta agttcaaggc actggccgat aagaagtaag aaatcacaga
     6181 tgcagatatt cgagctttgg tagctggaag catggttgaa aatccagaag gcttccactt
     6241 tgatgattta caacttcaaa ctcatgcaga taatgacatt gaagcgctcg ttagcctagc
     6301 caatatggat ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat
     6361 ctttaatgct atcgataagt tctttaacca atctgttcgt ttggtgtcct acactatcga
     6421 tgcggtaaca gatggaatcg atacccagga tcgggttttg gtcactgttg aaaacagaga
     6481 tacagaaacc atctttaatg cagcagggct tgattttgat gtgttgaagg cttctgctat
     6541 tgtctatata aacgctaata cctttgttca aaaagagaat gcaggtgaga tgggacgcag
     6601 tgtttcttac cacgatatgc ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta
     6661 gctctagtag gagacggaat tggcccagaa atcatggagg ttggtttaga agttctggag
     6721 gctctagctg aaaaaacagg ttttgactat gagattgaca gacgaccgtt cggaggtgca
     6781 gatattgatg cagcatggcc tcccttacct gatgaaaccc ttaaggcaag tagggaagca
     6841 gatgctatcc tactagcaac tatcggtagt cctcagtatg atggagcagt ggttcgccct
     6901 gaacaaggcc tgatgactct ccgtaaggaa cttaatcttt acgctaatat tcgtcctgta
     6961 aaaatctttg acagtctcaa gcatttgtca ccactcaaac tggaacgaat tgctggtgta
     7021 gactttgtcg tggtgcgtga attgacaggc gggatttact ttggagatca tattcttgaa
     7081 gagcgcaatg cgcgtgatat caacgactat agctatgagg aagtggagcg gattattcgc
     7141 aaagcctttg aaattgcaag aaatcgcaga aaaatcctta ctagtatcga taagcaaaat
     7201 gttctagcga cctcaaaact ctggcggaaa gtagctgagg aagtcgcaca ggatttctca
     7261 gatgtaacct tggaacacca gctggtagac tcagctgcta tgcttatgat taccaatcct
     7321 gctaagtttg atgttattgt aacggagaat ctttttggag atattttatc tgatgaatca
     7381 agcgtcttat ctggtacact tggggttatg ccatcagcca gtcattctga aaatggacca
     7441 agtctctatg aacctattca cggttcagta cctgatattg caggtcaagg aattgccaat
     7501 cctatttcca tgattttatc agtttccatg atgttaagag atagtttcgg aggttatgag
     7561 gatgcagagc gtatcaaacg tgctgttgag acaagtttgg cggcaggaat tttaacgaga
     7621 gatataggag gtcaggcttc aacaaaggaa atgacggaag ctattattgc aaggttatga
     7681 agttagacga aaaaattact ctagtccttt tgatttggaa tgtcatcatt ttcttgattt
     7741 atggcattga caaattcaag gcaagaagaa gagcttggcg catcccagag aaaatcttac
     7801 tcattttagc ccttacttgt ggtggttttg gggcctggtt agctggaatc acttttcacc
     7861 acaagactcg aaaatggtac tttaaaacag tttggtttct tgggatggtg accacactag
     7921 tagccttata ttttatttgg aggtaatgga tggcagggtc ttcgagggaa cacgctgctt
     7981 gggctctagc ggactatggt tttaaggtcg tgattgcagg atctttcggt gacattcatt
     8041 acaataatga actcaataat ggcatgttgc caatcgttca gcctagagag gttagagaga
     8101 aactagccca gctaaaacca accgaccagg taactgtgga cttggaacaa caaaaaatca
     8161 tctcaccagt tgaagaattc accttcgaga tagatagcga gtggaaacat aaactcctaa
     8221 atagtttgga tgatatcggt attaccttgc agtatgaaga gttgattgct gcttatgaaa
     8281 aacaacgacc agcctactgg caggattaga aaaaatagaa aaggaaatat agtaaactga
     8341 aataagatgt aaacaaatga attggagctt aacatccatt tccagcaatt ttttagaaac
     8401 tacagtggac tattctggat tcaacacatt ataaaattat gacaaaacac attcacaaga
     8461 aggctacgac attttaaaag gtgagggcgg atgtatcgtt tgccctacta aagttggtta
     8521 cattatcatg accagcgaca aggcaggact tgagcgtaag tttgcagcca aagaaggtaa
     8581 gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat gaactttgcg ctttagcgca
     8641 actcaaccca aaaattgaag cattctacta aaaacattgg gatgaagata ttcttcttgg
     8701 ttgtatcctt ccttggaaac cagaagcctt tgaaaaactc aaagcatacg gggatggccg
     8761 tgaagaactt atgactgatg tacgtggtac tagctgtttt gttatcaagt ttggaaaagc
     8821 aggtgaacaa ttggctgcca agctttggga agaaggtaaa atggtctacg cctcatatgc
     8881 ttcaatgaca aaacgattga aactcgctat gagagcaagg tgtaatggtg tctatggtcg
     8941 ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacctca ccagcaccag
     9001 ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca gacaccttta
     9061 acttatggga ctaccgtcag gttgagtatt attaggatag agaagaagtc tagtgttaag
     9121 gacattacag ctcataatac taggcttttt tatagaaatt cttttctttt tctataggat
     9181 atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa acatcattag
     9241 taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt tataaatggt
     9301 atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag tttaatgata
     9361 aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca atgtcaatcg
     9421 atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct cttgagaagg
     9481 gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa tttggtattt
     9541 attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt tcagagttgg
     9601 atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt
     9661 ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt attggtcgtt
     9721 ctgctatggt gacaaaatta ctttgtatct attctgaggg agattctttc tttggtgtaa
     9781 atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat caaggtggac
     9841 cttatctgca aaatcataaa ataattgaac tggtgccaaa acttatcctg agttggagcc
     9901 atcgaaatta ggaactatgc tttttgagta ttctaagctt tttatggaaa ataaggaaga
     9961 caatagtaca atggattcat caaacaattt tcgtcatcaa ttaactcaat ctctattaaa
    10021 gtctccaaac cttatccttc gtggtgctcc tggcacagga aagacttatc ttgctaaaga
    10081 aattgccaaa gaattaacgg atggcaacga agaccaaatc ggatttgtac aatttcaccc
    10141 atcatatgat tatacggatt ttgtagaagg tttaagacca gtatcaaatg gggatggagc
    10201 tattgagttt aggctacagg acggtatttt taaagatttt tgtcagaaag caaaagaaac
    10261 ccaattgatt ggaggacaag ataattttga tgaggcttgg gattcttact tagaatatat
    10321 aaatgttgct gaagaaaaag aatatataac aaaaacatct tacttatctg ttaatagtag
    10381 acaaaatttg tcagtaaatt atgatagtgg tgttccagga tggtcactac ctagcaaata
    10441 tgtttacgag ttgtataaag ataaaaatta taataagcaa gaatactaca aaagtggtgg
    10501 aaaaactgtc ctagaaacat tgagaaagag atttggtttg aaagactatg tttccccaac
    10561 agaaattgat actgataaga aattcgtctt catcatcgat gaaatcaatc gtggggagat
    10621 ttctaagatt tttggcgaac tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg
    10681 aagtgtttct acccaatatg caaatctaca cgaaactgat gaaaagttct atatccccga
    10741 aaatgtttac atcatcggaa ctatgaatga tattgatcgt tcagtggata cctttgattt
    10801 tgctatgcgt cgtcgttttc gttttgttga agttactgcc gagggtcaag ttggcatgtt
    10861 ggataaagag ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc
    10921 tgctatcgaa aatgttcagg aattaaacag tcattatcat attggaccaa gttattttct
    10981 taagttgaag gatgtagatt ttgactatga attactctgg tccgattata ttaagcctct
    11041 cctagaagac tacttgcgag gttcttatga tgaggttgaa actttggaaa ctttgaaaaa
    11101 agcatttgaa ctgacaaata atgagcaaaa agatcaggca gtagctgatg acaatgaagg
    11161 tgatgaaaac gatgatgcgg attactgata atcaacacaa gattattaaa gaaaaatttg
    11221 ttgaagaata tcctaaacta agcaatcttc ttttagacag aaccttggaa agtctatccc
    11281 aagatgaacg tattttcatt tttccaaatg atttgactca tactcctgat ttggataagg
    11341 accaaaagat ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg attggttttc
    11401 ttggatatgg tcaggaaaga ttaacgattt cctcacgatt ttctgatgag agtaatgacc
    11461 attttttgca ttatctctta aacaaggttc ttcatatcaa tctcactagt ttagatgttg
    11521 ctttgtctcg tgaagagagg ctttatcaac ttttggtgta tctctttccc aagtatctac
    11581 aagctgctat tcgaaaaggt ctttataagg aatatcatcg attttctcat aacgacagta
    11641 atgttaaggg agtgattgat gtaagaagcc atctcaagaa aaatcttcct ttcacgggaa
    11701 atattgccta cgcaacgaga gagttcacct atgataatcc cctcatgcag ttggtccgtc
    11761 acactattga atacattaag aatcagaaaa gcattggtca aggggtacta gataatctct
    11821 caactagtcg tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat aaactagctg
    11881 atcgtgctaa gattattcgg ggaaatcaat ctaaacctat acgtcatgca tactttcacg
    11941 agtacagaaa cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag cacggtttag
    12001 ggtatcaaga tcaaaaaatc tatggtattc tctttgatgt tgcctggctt tgggaagagt
    12061 atgtttacac cttgttgcca aaaggttttg tacatcccag aaataaggat aagacggatg
    12121 gaatttcagt attttctgtt gggaaacgaa aagtatatcc agatttttat gacagagaac
    12181 gaaagattgt tctagatgca aaatataaaa aactggaatt gactgaaaaa ggaatcaacc
    12241 gtgaggactt attccagctg atttcctatt cttatatttt aaaagctgag aaggctggac
    12301 tgatttttcc tagtatggag cagtcagtaa atagtgaaat aggaaaagta gctggctatg
    12361 gagctcaatt gaagaagtgg tctattcgaa tccctcagaa tgcctcattc tatagtacat
    12421 tttgtaaaat gatggaaaat tcagaagaaa attttaaagc gattattgat gaagaagtgg
    12481 ggagaaaata atttcccctc tttcttttat ttttaacaca agtaaaaccc gaacgatata
    12541 ttttaattca taaaataatt tgacaaaaac tgtactttgg tttataataa attaaggaaa
    12601 cgtcggaaaa ggcgtagtga tgcaagagca taggtaggtc attacaaaag aaacgagaca
    12661 tcgatatgtt aaatgaattt ccaatttttg attacgaaga tattcaattg attccaaata
    12721 aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt cactttagga aatcacacct
    12781 ttaaactacc tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat gtagcagagc
    12841 aactggctaa aggtggttac ttctacatta tgcaccgttt tgatgaggca ggacgcattc
    12901 cttttattaa acgaatgcac gatcaagggc tcattgcttc tatctctgtc ggtgttaagg
    12961 attatgagta tgatttcgtt agacagctca aggctgatgc tcctgagtat atcactattg
    13021 atattgctca tggtcatgcg gatagcgtga tttctatgat tcaacacatc aagaaagaat
    13081 tgccagatac ctttgtcatt gctggaaatg tgggaacacc agaagctgtg cgtgaattgg
    13141 aaaatgctgg tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt tgtatcacca
    13201 aggttaagac tggttttggt acaggtggtt ggcagttggc tgctctacgc tggtgtgcca
    13261 aggctgcgcg taaaccgatt atcgctgatg gaggaattcg tactcacggt gatattgcta
    13321 agtctatccg cttcggtgct agcatgatca tgattggttc cctctttgca ggacacattg
    13381 aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat tatggttcag
    13441 cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc ttgcttcctg
    13501 ctaaaggtca tctgcaagac actttaactg agatggaaca agaccttcaa agtgctattt
    13561 cttatgcagg tggacgtcag gttgctgacc ttaaacacgt tgattatgtg atcgtgaaaa
    13621 actccatctg gaatggggat gcttcccact aagacggggt ctttgaccaa aaaacttgtt
    13681 attagagcaa atttctgtta taataaaaca agtttccacc cttagtgtaa tggatatcac
    13741 gtaagattcc ggttcttgag atgggggttc gattccctca gggtggatgt aaacatccta
    13801 aaaagccttt aatagggctt ttttctttat cctgacccaa atttgccgct aaaactgaga
    13861 atctctgtct aaagaattcc caaatgcttt ccagtcccgt tttagagtga ctcagggggc
    13921 tttttttgat ataataaaaa ggactattat cagttagaaa gaggttggta tgaaagaatt
    13981 acaaactgta ctaaagaatc attttgcaat cgaatttgca gacaaaaatt tactggaaac
    14041 tgcctttact catacgagtt atgccaatga gcaccgcctc ttaaaaattt cacacaatga
    14101 acgcttggaa tttttaggag acgctgttct acagttattg atttcagaat atctatataa
    14161 aaaatatcct aaaaagcctg aaggtgacct atcaaaactc cgtgctatga ttgtccgtga
    14221 ggagagttta gctggttttg cgcgtgattg ccagtttaac cagtttatca agttgggtaa
    14281 aggggaagaa aaatcaggtg gtcgcaatcg tgacaccatt cttggtgatg cctttgaagc
    14341 ctttcttggt gcccttcttt tggataagga tgtggccaag gtcaaggaat ttatctatca
    14401 agtcatcatt cctaaggttg aagcaggcga gtttgagatg attacagact ataaaaccca
    14461 tctccaagag ttgcttcagg tcaatggtga tgtggctatt cgttatcagg tgatttctga
    14521 aacagggcct gctcatgata aggtctttga tgtagaagtt cttgttgaag gtaagagcat
    14581 cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag gaagctgcca aaaatgccgt
    14641 tgagaagggg ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt caagtctttt
    14701 gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg acccaatgga
    14761 tctggaaagt ccaatattac agaaagtctg cgttgggctt tgggggagtc tagtgtcaag
    14821 agtctccgtg ggggcaagat gccggatgtc atctttgctg gaaccgaaag tcgcaaaccg
    14881 ctcaattatg cttctgtagt tgtgactctg gataatcatg acggatttat caaggatgca
    14941 ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg gagatagcga atacaagatt
    15001 gacggcaaga aagtccgtct gcgtgatatt catgacctct tcttggatac tggattggga
    15061 cgagattcct tctctattat ttcccaaggg aaggttgagg agatttttaa ttccaagcct
    15121 gaggaacgac gagctatttt tgaagaagct gctggagttt taaaatacaa gactcgcaga
    15181 aaagaaaccg agagtaaact gcagcaaact caggataatc tggaccgctt agaggacatt
    15241 atctacgagt tggataatca aatcaagcct cttgaaaagc aagctgagaa tgcccgtaag
    15301 tttttagact tggaaggaca acgtaaggct atttatttag atgttctggt tgctcaaatc
    15361 aaggaaaata aggctgaact agagtcgaca gaagaagagt tggctcaggt tcaagaactc
    15421 ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac tcttaaaaag
    15481 caacgccaag atttacaggc tgaaatggcc aaagaccaag gcagtttgat ggatttgacc
    15541 agtctgatta gtgacttaga gagaaaatta gccctatcga aactggaatc tgagcaagta
    15601 gccctcaatc aacaggaagc acaagcccgt ttggctactt tggaggataa gagaagttca
    15661 ctcagccaag aaaaatctga taaagaaagc tctttagccc tcttggaaga aaatctagtc
    15721 caaaataatc aaaaactcaa tcgattagag gctgaattgc tagctttttc agatgatcct
    15781 gatcagatga ttgagctctt acgtgaacgc tttgtggccc ttttacaaga agaagcagat
    15841 gtctcaaacc aactgacccg tattgagaat gagttggaaa atagtcgtca gctttctcaa
    15901 aaacaagcag atcaactaga aaagctgaaa gaacagttgg ctacagctaa agagaaggct
    15961 ggtcagcaaa aggctgagct tgaaactgcc aaggagcagg ttcagaaatt attggccgac
    16021 tatcaagtct gtgctaagga gcaagaggag cagaaaactt cctatcaagc tcaacaaagt
    16081 caactctttg accgtctgga tagtctcaaa aacaagcagg ctagagcgca aagtttggaa
    16141 attatcctga gaaatcatag taacttttat gcaggtgtta agagtgttct ccaagagaaa
    16201 gatcgtctag gtgggattat tggagcagtt agtgagcacc tgacctttga tgtgcattat
    16261 caaactgccc tagagattgc gcttggagcg agtagccaac atatcatcgt ggaagatgaa
    16321 gagtcggcaa ccaaggcgat tgatttactc aaacgaaaca gatctggtcg tgcaaccttc
    16381 cttcctttga ccactatcaa ggctcgtacg atttctagtc agaaccaaga tactattgct
    16441 gcaagtccag gatttctggg catggcagat gagctggtta ctttcgatac tagactggaa
    16501 gccattttca agaatttgct agctacaacg gccatttttg ataccgtgga gcatgcgcgt
    16561 gcagcagcgc gccaggttcg ttatcaggtt cgtatggtga cattggacgg aacagagctg
    16621 cgcacaggtg gttcttatgc aggtggagct aatcgccaga ataacagtat tttcatcaag
    16681 ccagaactgg agcaattaca aaaagaaatt gctgaagaag aagcaagttt gcgttcagat
    16741 gaagtgagtt tgaagaactt gcaagatgag ctagctagat tgacagaaag attagaagcc
    16801 atcaaatctc agggagagca ggctcgtatt caggagcaag gcttgtccct cgcctatcag
    16861 cagaccagtc agcaagttga agagctagaa actctttgga aactccaaga agaggaatta
    16921 aatcgtcttt ctgagggaga atggcaagcg gataaggaaa aatgccaaga gcgccttact
    16981 acaatcacta gtgaaaagaa taatctggaa gctgagattg aagagattaa gtctaataaa
    17041 aacgccatcc aagaacgtta tcaaaacttg caggaagagc tagctcaagc tcgtctactt
    17101 aagacagaac tgcaagggca aaaacgttat gaagttgctg atattgaacg cttaggtaag
    17161 gaactagata atcttgatat tgagcaagaa gaaattcagc gccttcttca agaaaaggtt
    17221 gacaatcttg agaaagttga tacggatttg ctcagtcaac aggctgatga agccaaaact
    17281 caaaaaacaa atctccaaca aggtttgatt cgcaagcagt ttgagttgga tgatattgag
    17341 ggtcaactgg atgatattgc tagtcatttg gatcaggctc gccagcagaa tgaagagtgg
    17401 attcgcaagc aaactcgtgc tgaagccaag aaagaaaagg ttagcgagcg cttgcgccat
    17461 ctacaaagtc aattaacaga ccagtaccag atcagctaca cagaagcttt agaaaaggcg
    17521 catgagttgg aaaatctcaa tctggcagag caagaagtta aggatttaga gaaggctata
    17581 cgctcactgg gtcctgtcaa tttagacgct attgaacagt acgaagaagt tcacaaccgt
    17641 ctggatttcc taaatagcca acgtgatgat attttgtctg cgaaaaacct gctccttgag
    17701 accattacag agatgaatga tgaggtcaag gaacgcttta aatcaacctt tgaggtcatt
    17761 cgtgagtcct ttaaagtgac cttcaagcag atgtttggtg gaggtcaggc tgacctcatt
    17821 ttgactgaag gagacttgct gacagctggg gttgaaattt ctgtccaacc accaggcaag
    17881 aaaatccagt ctcttaatct catgagtggt ggtgaaaaag ccctatcggc tcttgccttg
    17941 ctcttctcca ttattcgtgt caagactatt ccatttgtta tcttggatga ggtggaagct
    18001 gcgctggatg aagccaatgt taaacgtttt ggggattacc tcaaccgctt tgacaaggac
    18061 agccagttca tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga ttccatctat
    18121 ggagtgacca tgcaagaatc gggtgtttca aagattgttt cagttaagtt aaaagattta
    18181 gaaagtattg aaggatgaca attaaactag tagcaacgga tatggacgga accttcctag
    18241 atgggaatgg acgctttgat atggatcgtc tcaagtctct cttggtttcc tacaaggaaa
    18301 aagggattta ctttgcggta gcttcgggtc ggggatttct gtctctagaa aaattatttg
    18361 ctggtgttcg tgatgacatt attttcatcg cggaaaatgg cagtttggta gagtatcaag
    18421 gtcaggactt gtatgaagcg actatgtctc gtgactttta tctggcaact tttgaaaagc
    18481 tgaaaacttc accttatgta gatatcaata aactgctctt gacgggtaag aagggttcat
    18541 atgttctaga tacggttgat gagacctatt tgaaagtgag tcagcactat aatgaaaata
    18601 tccaaaaagt agcgagtttg gaagatatca cagatgacat tttcaaattt acaaccaact
    18661 tcacagaaga aacgctggaa gatggggagg cttgggtaaa cgaaaacgtt cctggtgtta
    18721 aggccatgac aactggcttt gaatccattg atattgttct ggactatgtc gataagggag
    18781 tggccattgt tgaattagtt aaaaaacttg gtatcacaat ggatcaggtc atggcttttg
    18841 gagacaatct taatgactta catatgatgc aggttgtggg acatcctgta gctcctgaaa
    18901 atgcacgacc tgaaatttta gaattagcaa agactgtgat tggtcaccat aaggaacggt
    18961 cggttatagc ttatatggag ggcttataat ggcagatata aaattgattg cattggactt
    19021 ggacgggacc ttgctgacta ctgataaaag gctgacggat cgtaccaagg aaaccttgca
    19081 agctgcgcgt gatcgtggta tcaaggtcgt attgacaact ggtcgtccct taaaagccat
    19141 ggatttcttt ctccatgagt tagggactga cggtcaggaa gatgagtata ccattacttt
    19201 taatggtgga ttagttcaga aaaatacagg agaaatcctt gataaaacag tcttttcata
    19261 tgatgatgtg gcacgtttgt atgaagaaac agagaaatta tcactgcctc ttgatgccat
    19321 ctcagaagga acagtttatc aaatccaatc ggaccaagaa agtctttatg ccaaattcaa
    19381 tccagctttg acctttgttc cagtggactt tgaagactta tctagtcaaa tgacctacaa
    19441 caaatgcgtg actgcctttg ctcaagaacc cttggatgca gccattcaga agatttctcc
    19501 agaattgttt gaccaatatg aaatctttaa atcacgtgaa atgttgctag aatggtcacc
    19561 aaagaatgtt cataaagcaa caggtttggc aaaactaatc agccatcttg gaatcgacca
    19621 aagtcaagtg atggcttgtg gtgacgaggc caatgacctc tctatgattg aatgggcagg
    19681 tcttggtgtt gctatgcaaa acgctgttcc tgaagtaaag gcagccgcaa atgtagtgac
    19741 gccgatgacc aacgatgagg aagctgtcgc ctgggctatc gaagaatatg tgctaaagga
    19801 gaactaagat atgggattgt ttgaccgtct attcggaaaa aaagaagaac ctaaaatcga
    19861 agaagttgta aaagaagctc tggaaaatct tgatttgtct gaagatgttg atcctacctt
    19921 cacagaagtt gaggaagttt ctcaggaaga agcagaggtt gaaattgttg aacaagctgt
    19981 gttccaagaa gaggaaatcc aagacacagt tgaagaaagt caggattcag agccagctgt
    20041 aggggtttct caagaagaaa tagaagaatt accaaactca gaagaattac cagaggaaga
    20101 gaagcttgag cacgaaggaa ctgtagaaga aaataattct gaagtgcttg aaccagaagc
    20161 tcctcaaaca gaagaaactg ttcaggaaaa atatgaccgc agtcttaaga aaactcgcac
    20221 aggtttcggt gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt
    20281 tttcgaggaa ctggaagaac tgctgattat gagtgatgtt ggtgtccaag tcgcttctaa
    20341 cttaacggag gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgtact
    20401 tcgtcgtgtc atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga
    20461 aagcatccac ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg
    20521 gaaaacaact tctatcggaa aactagccca ccgctacaaa caagctggta agaaggtcat
    20581 gctggttgca gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg
    20641 acgagtagat gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt
    20701 tgatggtatg gaacgtgccg tgactgaagg tatcgatatt ctcatgattg atactgctgg
    20761 tcgtctgcaa aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa
    20821 acgtgttgtg ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca
    20881 aaatgcccta gtacaggcca aagaattttc gaaaatcaca cctttaacgg gaattgtttt
    20941 gactaagatt gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa
    21001 tattcctgta aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc
    21061 agaaaacttt atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca
    21121 aggcataaac ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggtgatat
    21181 ctggttgcca agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc
    21241 ccatgcttcc agctttatag tcatgaagtg gggcaccatt ttcagcccag agcttttcaa
    21301 tacggtcaat caacttccat gacgcacaaa cttcatccca gtggctaaag ttagttgagt
    21361 tgttatttag gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag
    21421 tcgcatctgt acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct
    21481 tcccatttag gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg
    21541 gagcaagtgg ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgggttc
    21601 ctttttcagt cagtcgttta cctgtacgga aaaagaaagg aacaccacgg aatcgatcgc
    21661 tgtctacaaa gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg
    21721 gctcgctacg ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac
    21781 ggataaagtg ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa
    21841 tcttttcagc acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg
    21901 aaagaagttg tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt
    21961 agccaccacg ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa
    22021 aatccttgtt ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt
    22081 ggatcatttc cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg
    22141 ctaggagttc gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa
    22201 cgatcaagcg ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa
    22261 tggttccaaa gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt
    22321 atttttcatt aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga
    22381 catcatggct ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg
    22441 ccaaatcaag gatggactcg acaactacag attcaaaata ttccttactc caaggtctac
    22501 gggcagttcc aataacggca aagtgcttgg aaagattgcc ggattgatat agtctaaaaa
    22561 gggaagggta gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa
    22621 ccttagatga catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag
    22681 gaaacctcat ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat
    22741 acgaggtaga aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta
    22801 tctaagaact ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg
    22861 tcttcaagga actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat
    22921 cccatctcat gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg
    22981 ttaagtacgt ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg
    23041 atgtctggat tcattgctag gccacgagcg atggccacac gttgtttttg accacctgat
    23101 aggctatctg gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt
    23161 cccaattcct cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg
    23221 ttgtccaata cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt
    23281 tcacggacgt ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg
    23341 tgaccgctag tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa
    23401 cctgaaggac cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt
    23461 aggacttcat tttttccata gtgcttgtgt aaatcattta catcaatttt taattttacc
    23521 attaacgaat cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa
    23581 gatagaagat agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa
    23641 tcttaccagt ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa
    23701 gagcgataac gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga
    23761 taatcttacg catggttttt ccataagaga tacccaagct tcggctggct tccatttggc
    23821 caactggaac ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga
    23881 gtgagagggc aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag
    23941 actcgatgaa gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac
    24001 cacgaataac gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc
    24061 taaacatacc gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag
    24121 caagagtgat accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga
    24181 gcgttgtttc gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt
    24241 caagaatctt ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt
    24301 caatcagttc tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc
    24361 cagagattgg agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat
    24421 catccataac ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag
    24481 caaaggtttt gattttgtag ccgtatttgc tttgattttc tgttaggaag gtttgagaag
    24541 cagttccgtt tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc
    24601 ttgattcttt gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag
    24661 ttgccttacg agcatctgtg acagacatac cagcgatgat accatcggct tgaccagctt
    24721 ggacagcact gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt
    24781 ctttagcgat tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt
    24841 ggaaaacaaa aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa
    24901 tagcttttaa tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc
    24961 atttcttgat aattttatca agactaccat cttttttcat ttcagacaag gcttggttaa
    25021 attcagtaac caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta
    25081 cagcttcacc atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa
    25141 caggtttgtc atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat
    25201 caccagtgtc aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac
    25261 gttgagcggc agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc
    25321 taattttgtg tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca
    25381 tggtgaagac tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt
    25441 gcccagcttg aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc
    25501 agcctttaat ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat
    25561 ctgaatcttt aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg
    25621 ctttggcaat acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt
    25681 tcttcatttt tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa
    25741 ggcaaatttt tatatttttc gtgtcagaaa atataacatc gattttttcc tttccttgaa
    25801 ttgctat
//
LOCUS       DAVKUR010000025        25737 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKUR010000025 DAVKUR010000000
VERSION     DAVKUR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.025"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            114..278
                     /locus_tag="VW749_001198"
     CDS             114..278
                     /locus_tag="VW749_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0175238.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            362..928
                     /gene="amaP"
                     /locus_tag="VW749_001199"
     CDS             362..928
                     /gene="amaP"
                     /locus_tag="VW749_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0175239.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            940..1110
                     /locus_tag="VW749_001200"
     CDS             940..1110
                     /locus_tag="VW749_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0175240.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1149..1757
                     /locus_tag="VW749_001201"
     CDS             1149..1757
                     /locus_tag="VW749_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0175241.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1788..1991
                     /locus_tag="VW749_001202"
     CDS             1788..1991
                     /locus_tag="VW749_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0175242.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2086..2364)
                     /locus_tag="VW749_001203"
                     /pseudo
     CDS             complement(2086..2364)
                     /locus_tag="VW749_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2562..2849
                     /locus_tag="VW749_001204"
     CDS             2562..2849
                     /locus_tag="VW749_001204"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0175243.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3127..3897)
                     /locus_tag="VW749_001205"
     CDS             complement(3127..3897)
                     /locus_tag="VW749_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0175244.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3912..4760)
                     /locus_tag="VW749_001206"
     CDS             complement(3912..4760)
                     /locus_tag="VW749_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0175245.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4757..6232)
                     /locus_tag="VW749_001207"
     CDS             complement(4757..6232)
                     /locus_tag="VW749_001207"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0175246.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6555..7910)
                     /locus_tag="VW749_001208"
     CDS             complement(6555..7910)
                     /locus_tag="VW749_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0175247.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7920..8237)
                     /locus_tag="VW749_001209"
     CDS             complement(7920..8237)
                     /locus_tag="VW749_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0175248.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8254..8571)
                     /locus_tag="VW749_001210"
     CDS             complement(8254..8571)
                     /locus_tag="VW749_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0175249.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8584..10269)
                     /locus_tag="VW749_001211"
     CDS             complement(8584..10269)
                     /locus_tag="VW749_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEV0175250.1"
                     /translation="MKNKKLILSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(10274..11170)
                     /locus_tag="VW749_001212"
     CDS             complement(10274..11170)
                     /locus_tag="VW749_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0175251.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(11173..12435)
                     /locus_tag="VW749_001213"
     CDS             complement(11173..12435)
                     /locus_tag="VW749_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0175252.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            12715..13893
                     /locus_tag="VW749_001214"
     CDS             12715..13893
                     /locus_tag="VW749_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0175253.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(14121..14567)
                     /locus_tag="VW749_001215"
     CDS             complement(14121..14567)
                     /locus_tag="VW749_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175254.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVQKYSRLKLE"
     gene            14637..15296
                     /locus_tag="VW749_001216"
     CDS             14637..15296
                     /locus_tag="VW749_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0175255.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLL
                     V"
     gene            complement(15348..16499)
                     /locus_tag="VW749_001217"
     CDS             complement(15348..16499)
                     /locus_tag="VW749_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0175256.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(16514..17245)
                     /locus_tag="VW749_001218"
     CDS             complement(16514..17245)
                     /locus_tag="VW749_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175257.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            17474..17575
                     /locus_tag="VW749_001219"
                     /pseudo
     CDS             17474..17575
                     /locus_tag="VW749_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(17547..18323)
                     /locus_tag="VW749_001220"
     CDS             complement(17547..18323)
                     /locus_tag="VW749_001220"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0175258.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(18316..19539)
                     /gene="trpB"
                     /locus_tag="VW749_001221"
     CDS             complement(18316..19539)
                     /gene="trpB"
                     /locus_tag="VW749_001221"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0175259.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGCPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(19517..20116)
                     /locus_tag="VW749_001222"
     CDS             complement(19517..20116)
                     /locus_tag="VW749_001222"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0175260.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     YFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(20103..20870)
                     /gene="trpC"
                     /locus_tag="VW749_001223"
     CDS             complement(20103..20870)
                     /gene="trpC"
                     /locus_tag="VW749_001223"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0175261.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(20867..21871)
                     /gene="trpD"
                     /locus_tag="VW749_001224"
     CDS             complement(20867..21871)
                     /gene="trpD"
                     /locus_tag="VW749_001224"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0175262.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIITGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(21882..22448)
                     /locus_tag="VW749_001225"
     CDS             complement(21882..22448)
                     /locus_tag="VW749_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0175263.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQTIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(22445..23806)
                     /gene="trpE"
                     /locus_tag="VW749_001226"
     CDS             complement(22445..23806)
                     /gene="trpE"
                     /locus_tag="VW749_001226"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0175264.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(24727..25728)
                     /locus_tag="VW749_001227"
     CDS             complement(24727..25728)
                     /locus_tag="VW749_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0175265.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         8079 a         5484 c         4132 g         8042 t
ORIGIN      
        1 aaattgattt tttgatatta aaataaaaaa ggagggtagg cagtgttgtg atcaattatt
       61 gctggaggtc ttattggtct cttggcaggt aaaatcacta aaaaagtagt tctatgggaa
      121 tcatcgcaaa tgtattcgct ggtttagtcg gggcatatgc aggacaatct cttttaggta
      181 gttggggtcc atcaatcgct ggaatggctt tgctcccatc tattgtaggt gcagcgattg
      241 tgattactgt agtgtcattc tttacaggta gaaagtaaac ttttcgccag taaagttagc
      301 aaactatttt taaatcaatg acgggaaaaa tagtttaaat gttaaatcga aaggattgta
      361 tatgtcaaaa gcaaagaaaa tatgtttcat tattttctgt attttaatct tgacaatttt
      421 ccttcctgtt ttgatagatt atcatcaagt tagtgatcta ggtattcatc tacttagctg
      481 gagacagaac tccgtagttg aattctatct tgctagatat gtcttttggg ggacagtggt
      541 tctatcaact ttagttttat tatccatttt agttgtgatg ttttatccta aacgttactt
      601 ggaaatccaa cttgaaacta aaaacgatac attaaaatta aagaattcgg caatcgaagg
      661 ttttgttaga agtttggtga gtgatcatag attgatcaag aacccaactg ttcatgtaaa
      721 tttacgaaaa aataaatgtt tcgttcatgt agaaggtaaa attcttcctt cagacaacat
      781 cgctgacaga tgccaaataa ttcaaaatga aataactaat ggattgaagc agttttttgg
      841 tattgagcgt caagtaaaac ttgaagttgc agtaaaaaat taccaaccaa aacctcaaaa
      901 caaaaagact gttagtcgtg tgaagtaagg aagtaaaaaa tggaatggct taaacaatat
      961 cgatatccaa ttatcgctgg tctcataggc gtatttctgg cttgtttgat tgtctccttt
     1021 ggcttcttca aaacaatatt tgtattgatt ttaggagcac tgggagttgc agctggatta
     1081 tatatcgaaa aaaactatat agataaataa aaaaataaaa attactaatt taattaaagg
     1141 agtttcatat gtcaaacgaa aaaaacacaa acactaacgt agaaaagaaa gatgctactg
     1201 ttgtagctca cgaaatcaaa ggggaactta cttacgaaga taaagttatc caaaaaatca
     1261 ttggtctttc actagaaaac gtttcaggtc ttttgggaat cgatggtggt ttcttctcaa
     1321 atcttaaaga aaaaatcgtt aacagcgatg acgtaacaag tggtgttaac gtagaagttg
     1381 gtaaaacaca agttgcagtt gacttaaacg ttattgttga gtaccaaaaa aatgttccag
     1441 ctttatattc agaaatcaga gaaatcgtat cttcagaagt tgctaaaatg actgacttgg
     1501 aaattgttga aatcaacgta aacgttgtcg acatcaaaac taaagaacag catgaagcag
     1561 actcagtaag ccttcaagat cgcgtatctg acgttgctga atcaacagga gaattcactt
     1621 cagaacaatt cgaaaaagct aaatctggtc ttggatctgg tttctcaact gttcaagaaa
     1681 aagttagcga aggtgtagaa gctgttaaag gtgcagcaaa tggtgtagta tctcacgaaa
     1741 acactcgtgt aaactaagat aaaataaata taacaggaga aattatcatg tcagtagaag
     1801 aaaaattaaa tcaagctaaa ggttctatta aagaaggtgt tgggaaagcc atcggtgatg
     1861 aaaaaatgga aaaagaagga gcagctgaaa aagttgtttc taaagtaaaa gaagttgccg
     1921 aagacgctaa agacgctgta gaaggtgctg tagaaggtgt taaaaacatg ttgagtggcg
     1981 acgataaata aggttaaaag ttactttatc tttttggtaa cattagtcaa gatgattctc
     2041 agaaaacaaa aagctagaga ttcccaattg cggaacccta gctttttaat tttgcctctt
     2101 tctcttatta tatttcagca ggttgttggc catgagtacg aatcccatgt caattctcac
     2161 ttgacgcttc cctctcagat gacatctctt ataacccaaa caaaccttta tctgcccaaa
     2221 gacagatttc atatcaatct tacgtttagc gaaaatttgt ctacccttgg aagataaaag
     2281 tgcctgatat tctttagttt ttaaacactg gtaacgttca ttcatataca gtcccttttg
     2341 aggggctgat tcaggttcat aatcgcagtc aacattgatt tcaaggctgt ttgctttcta
     2401 tctccccttt ttcatgatat attttcgtac aggtgcttca atagtttcta tagtaaaatg
     2461 aaccaaaaat agtacacgtt gcggtataat gttcttgtgg catattcatt agattttcgt
     2521 aaaaagttct ctcctatttg tgagcgaaca ggtatagtca attgattgtc agtttgaaga
     2581 ccaagagtcg taaggcaaag gatatggcag aatccatcca agggtggctg gcacaatttc
     2641 tagtgaacct ctttaaatct attacgtttg actgtggaaa agagttttca aaatggaaag
     2701 atatttccaa tcatcacgat agtgagagct tttttgcgaa tctaggatgt ccaagacagc
     2761 ggtgtctcaa cgaacattca aatagacttt taaggtgtca tgacttgcca aagcagacag
     2821 atttcaacga agtcagtcaa gaattttagg ctgggtaaaa actcaatttc aggagaaaat
     2881 gaaataaata ttcccacaat aaaatgcata gtatcaaagt ttttccaaca cctgatatta
     2941 tgcatttttt aattttaaag actttttccc agcctcaaga aatcacatcc cacctaaatc
     3001 ctttggatac caaatacctc atcaggtatt ttctgagttg gtaagactgt ctagcttaat
     3061 ttgacaaatg gagggcgtta aatccagttt ttacaggaag tctatttaaa tattttcaca
     3121 ctgaccttac aaaatatgaa acaaattata taaagtcatt cccatgacaa agaataacat
     3181 ccctttaaaa cagtatctta cccaattttc aggtaagact tttgatacaa ccgtccccaa
     3241 tacccctccg catatagaag caagaaaaat aactggaaca ggtgctaaat gatactgatt
     3301 taaacctgta accacaacaa ttgtagccaa atgagacagc tgggaaaaga aaataattgc
     3361 aagagaatac atcgttgctt cttttatcga aatagaaaaa aacaccatca ataaagatac
     3421 attgagcgga ccaccaccaa tccctaaaaa actagaaatt aagcccaata gaagaccaca
     3481 aatcatatag aatcctatct tatcaaattg ataagttttt ttaaaatctg ttaaaacaaa
     3541 tgatacaagt agcatcacaa atagtaaaat catttgaaca atggatacta gccgtactga
     3601 taattgagat aacaaaactt gaaaaataag atgacctaga aatcctccta aaacagaaga
     3661 aaaggatacc gtaaaaatca atctccattt tatctcttta ctttgtgaaa atcttttgat
     3721 tgttgaaata atcgccatta taaaaacaga gaaactagaa taaaaagcaa tatcactgac
     3781 cgaatggtat ccaaaactat ccataagtgg cttaattata attccaccac ccatgcctga
     3841 tatagaaccc aatccactag ctattataat gattagaaaa taaataatct caaccacttt
     3901 ttaagtccat cctattcttt caaacatcta aaacctagat ggctactagt ggaagtagaa
     3961 atacatccat ttctagcagc tactcggtat cgattacaat aagaacaatg acataaaaag
     4021 gaacctcctc tgatagcata ctcctcatct tgtatcccat attttggcaa ctcatagtca
     4081 tcttcattaa aactagctaa taaggtatat ctcggattgc gacaccattc ccaaacattc
     4141 ccaatcattt gatatagacc aaaatcatta ggtaaaaatt catagacagg agccgttcct
     4201 ataaatccat ctaaggcagt attttcataa ggaaatcttc cttgccaagt attggcatga
     4261 taatatccac cttctaaaag agtatctccc caaggatatt cagattgtct tcctcctcta
     4321 gcagcatatt cccactgtgc ttcagtcggt aaagacattc cgctccaatt acagaaagcc
     4381 aatgcatctt ctaaagcaac atgaactact ggatggtctt ctaaacccac tagattacta
     4441 ttctcaccgt agggatgttt ccagcaagcg ttcggaactt gtaaccacca cggagcccca
     4501 gcaggatgag gatatccctc cctttctgcc tctggaacga acaatataaa aacaaaagac
     4561 cactcttgtc gctcagctag tgttttatag cctgtttctt tcacaaattg agcaaattct
     4621 tgattcgtaa ctggagtatc cgcaatggaa aaatccttta cactaacagc gacttgagga
     4681 ccttcaaaat catctaaaaa gccctcttca gaatttgttc ccatcataaa tgtcccaccc
     4741 ttgatttttt tcattttcat gattgactat cccccgtttt cgttagagtt ggcgttattt
     4801 tagaaagttc aacaggaact aactcttcat ccacaacaaa accttcttct ctatatctaa
     4861 gaaagtctac taattttttc ttcatctgac gaacaatagg ttgatatttt tcacttggat
     4921 acaaatcatt catttcatgc ggatcttttt tcatatcaaa taactgataa tgatttaaaa
     4981 caggaaacca gataaatttc cactggtctg tcaaaatata ttgactagaa tcttttccta
     5041 aagcatgttc accatgaaat tctgttcgcc acccctcgta ctgtccaaat aataaattct
     5101 taacactccg tccatctagt tcatctgtag tagttcctcc tgccaaatcc acgagtgaag
     5161 gaaaaatatc ttgaattttc actaattgct tgattgttcc cctattacca gctatcaatc
     5221 cagccggatc gtaaataaac gaaggaatgt ggatacttcc ctgataagga tatccctttc
     5281 taaacagata atgttcacca agctgatctc catgatccga aacaaaccag ataatcgtat
     5341 ctttatcatg acgaaattct tttagggcag tcaaaaagcg actaatttga tggtctatat
     5401 gagtaatcaa tccaaaataa gcagcaacca ttcttctttg atcatcttcc tttaatttcc
     5461 ctcttaaagc ataaatagac ggaatttgct tttctaatac ttcccaattc ccgatatgca
     5521 aatcgagaaa ttgaggcaag cgttccatat acatatcaaa atagtatttt gggggattta
     5581 atggagcatg tggtttttca aaagacattt tgagaaaaaa aggaaccgtt ggatctcttc
     5641 tttgtaaaaa tgaaatggac tcactcacaa cccagtttgt tggatgtaac ttctcatctt
     5701 tatcccaagg tctagcttcc caagaattac aatccattcc gtcatcaatc aaatcaacat
     5761 cataaccaac tttacccttt aaaaaggcta gatagtcact agcataatca aattgacttc
     5821 cataagcctt atcatacttt ctatcaacat gtagataccc atcgtgaagt aagacatgat
     5881 caaacccaag tctctgtctg gaaggaaaaa catgcatctt accaatacac tctgtttgat
     5941 aacccatatc tttaaagact tttggaagag tattagtaaa attccaaggc acctcatctt
     6001 gataaccaac tcgtccactt ttatcttggt ctaagccagt caataaagct gccctagcag
     6061 gaacgcaaga aggaactgga gaataggcat tttcaaaatt ataacctaca ctagccatca
     6121 tatctaatgt tggagtgcta actagcttat ccttactatt caaggataag gcgtctgctc
     6181 tcatttgatc tacaacaatc aaaataatat ttggctgttt tgtctgaacc ataaaatctc
     6241 ctttctaata tggcaaaaga ggcacaagaa gatatctacc tttactgcac ccctttctat
     6301 atcaatctct ctatataaaa caataacatt cttgttatgt tttatagaaa aatgaactaa
     6361 aatatgacta aatcgattag gaaattcaaa tcattttcta gtactgtttt agaagttaca
     6421 gtgtactatt ccaacttcaa taaactataa acctttgtct aataacaatt ttagtggaga
     6481 taagaaatcc tacacctaac tcatcttaca cgtaatctat ttctatttta tcacaaaaaa
     6541 cgcaagtaag accattaact caattcagtt ttatctgcca ttttcacaaa tgggaaataa
     6601 gtcaagacac taataatcaa acaaacaact gataagatga tggcacgcca atcaaatgct
     6661 gtagagaaga aaccatataa aattggaggc attacccaag taacgttttg tgtaacaggt
     6721 gaaacaagac cccagcttgt tgcccagtaa gctaccgttg ccatgaaaac cgggctaagt
     6781 acaaatggta taaatagcaa aggattcaag acaactggta aaccataatt gaccggctca
     6841 ccaatattaa acagaactgg tgctagacca agtttagcaa cttttcgata atgactgttt
     6901 cttgaaaaaa ttaaaatagc aagtactaat cctaatcctc caaaccagac aaacgcccca
     6961 aaagacccac ttgtccatat ataaggaatc ggttcacctt tttggaaagc atccagattc
     7021 gctaacatag caactccaaa cagcccttcc atgatgggag ccaatacatt tcctccatgg
     7081 agaccaaaaa accagaataa cttattcaaa aagatcatca gaataactgc aaagaaactt
     7141 tgagacaaac ctagtaatgg cgtttgtaac accttgtaaa cccaatcaat caataagtca
     7201 ttgctaagta aatggaaaac ataagtcaag atggctacta tatacatcgc cataaatcct
     7261 ggaatgatag aagtgaacgg cttagcaatc gcagggggaa ctgaatctgg taacttgatt
     7321 acccagttct ttttcattac tttacagaaa ataatagagg ctaaaaatcc aatcatcatg
     7381 gctgtaaagt agcctctggc attaatatgg tttcctggaa tcacattccc aatagttacc
     7441 atcagatttt taccatcaaa tgctagatta tcaattcctt gtaagatttg atctaatttc
     7501 acatctccta catttgccaa agggaaactc tttgtaactg tacttccaat cgaaatgaca
     7561 aacgaagcaa gtgataccaa accagcagaa actgtatcaa ccttgtaaat cttagcgata
     7621 ttcactccca agcaatagat gaacaacaag gaaacaattg gtatacttcc cttgaatacc
     7681 aaattattga tgtcaacaag ccactgaaag gttttcgtaa tactttctag gtgaaattgt
     7741 tgtggtaaat ccactagaaa agcatttaat aacaaagcaa tggaacctgt cataataaca
     7801 ggcatagtcc ccacaaatga atcacgtaaa gcaactaaaa acttctgatt cccaactttc
     7861 attgcaattg gagaaagttt ttcttgcatt ttatccaaca ttgtattcat accaaactcc
     7921 taattttttt caaatcgttc gtatacttct accacttctt tcgccaagtc aacaaaagtc
     7981 agactcgtca ttaaatgatc ttgcgcgtgt accatcaaga ggctaattga tgttttttcc
     8041 ccctgtgcct ctcttgtcaa catttctgtt tgagccttat gcgcctgtaa taaggcagca
     8101 ttcgcatcag ctaatcttcg attggcttta gagaaatccc ctttttttgc tgcctgaata
     8161 gcctccatag cattactttt ggcttcccca ccatacataa ttagccccat tacagattct
     8221 aaattacttt catccataac attctcctca atcttagtct aataaacttt cagctaaatc
     8281 taaaacttta gaaccattca tcattccgta atctgtcatc ggaataaccg ccacaggaat
     8341 ctgtctatct tttagttttt cttgaaagtc ccctagtaaa tagcgaactt gaggacctaa
     8401 aagcaacaca tttacttctt ttgttgctac aatttcttct gcttcaggag ctggaactgc
     8461 aaaaatttct gcatccaacc ccttatcttc tgctgccttt tgcatctttg tcactagcag
     8521 acttgtactc atacctgctg cacatgctaa cataattgtt actttagcca tagcttactc
     8581 cttttatttt attgtcaatg ttactgtttt tcgatcaact ttagactcat aatctaaatg
     8641 tttgggacga ctagtataat gcaaattata aactcctgga ggcatttgtg aaatcttttc
     8701 tttttcagtt ttattgcgaa ttaataaatc taccgaagta ttccctccaa agttattaaa
     8761 cataggttca ttttcaatag aataatctaa ctcatatcca ctattagttg taattccttt
     8821 taataaatca ggaacatctc ctctgtttat tactatatcc ttagcgccat ttattttggg
     8881 agattgacta taatactctt cagcttgatg ttgttgtaaa tcatttctag agtaagaaac
     8941 ataatcaact acaaattcag tccctgataa attattgtcc actaccccag gccaacttcc
     9001 tcccatcgct aaatttaact gaacatactg aggtctatta aaaatctttt tcgctatatt
     9061 atctgatcca taatatactt ttctaacaat atgattgtca accatccata caatataatc
     9121 tttataccaa tcaattgaaa aagtatgata cgaatcatta aagtttccac tcgataattt
     9181 aaaggctgta ccacgtcctg caaattttcc atcatcatta tccgactgtc cataatgaag
     9241 cgtttgataa actgtcttat tcccacttcc atttgaattt cgttcaccaa ctaattccat
     9301 tatatctatc tcacctgttg acggccatcc tcgtccctga acaggattaa tcttcccatc
     9361 aagtgtaaaa tccgatccaa gagtccagaa agcaggaaaa actccttgac ctttcggtaa
     9421 ttttgcacgc atctctaatt taccataaag aaattctact ttcccatgtg ttctaacact
     9481 tcctgaatta tatacaacct ttctgtgatt gtttcttggg ttaaaatact gatcttcctt
     9541 agagcgattc gtagctctaa gaactaaatt tcccgaacgt agaaaaacat tctcatcact
     9601 tcttacataa tgttgctgtt cccaaccacg aattgatcct aattcatatc cccaatattt
     9661 tttatttaat tgttcgccat caaaatcatc tctccaaatt ttcttatatg aatttccttt
     9721 agacagttga tacatctcta cattatcaat aaaaatatta gatttttttg tagtatcgtc
     9781 ttctgaccat ttcactaatt gaatcaaaac tttatcgtgt ttaccggaat tgaaagaaaa
     9841 catgtatttt ttccattcgg ttgtattaac tgtttgatca acagcttctc caatgttatt
     9901 ttgaacaatc tctccttgct tattattatc aaaccatctt gcggtaaaat atccctctgc
     9961 tccactaata tctactttgg caaaagcaga tactaaataa tcttcattag gttctatatc
    10021 aataacttgt ccaatatatc catctgctct attatcatta attgcagtag aaggaatcat
    10081 acctgagtaa tgtccgttac tataactctc atttgaatta attattcccc tatttctaga
    10141 gttccaaaac agctctcctt gctcaaaatt tgaatttttt attaaatttt cattagcaaa
    10201 aactttcgca tgaataaata ttaataaaaa taatataaat aaacttaaaa ttaatttctt
    10261 attcttcatt ttatcaccta tttactgacc tagccaagcg agatactgta tgtctcactc
    10321 ctctaattgc cttgctcaat gcataaatat tatcgactgt tgccagtccc ccatatcctg
    10381 cgtcacctat atgttgaata tcaactccac aaattttatt tctaagtgca atttccttga
    10441 tagtatctgt atcagatgtt tcttggctag taccaatagc actcaataca agaccaccct
    10501 tactatgaac gagatcaacg acttcacgca actcttggtc atgaaaggct ggaacggttc
    10561 caactgctgg aacaagtatc acatccgcac ctgcttccaa caattgctct gcgacagaaa
    10621 gctctgccac aggctcattc actcctgccc cgtgcatttt accagctata atcaaacctg
    10681 agaaattctc tttagcagat tgaactgctt tgataatctc ttgattgcta actcctgttc
    10741 caggatttcc agtcaaacag acaaagtcaa aacctaactc ctctattcga ttcaatgttt
    10801 caacactagc aacacgacct gcaacaattt cctgtgtttc ctctagcatc tttgcagatg
    10861 ggtcaatcgg ttccaaattt acaccaattg gacaagcaac aagctggtgt aagcgatgaa
    10921 taacatcatc acctgaacta tccaaagcat aaattttagg ctcaaaaaca tcaacacaat
    10981 tcaataaaat catatcagct ccaaaagctc tagcaatttc agaattagtt atatccccaa
    11041 caaatgtctc acgagtaact acattttcag atagaacaac tctaccttca cttgctaaaa
    11101 tactttgttt taattcttca gcattcatct gtaatatctc agatggattt gcactaatta
    11161 aacgtttcat tctcaatcct ccaataactt aaaccgtttt tcaatagcta ttacaaatgg
    11221 taaataaagt aagacatcca aaacaatcaa tacaatttgt aataatgaac cagaaatact
    11281 tcctgtagca agtaaaccac ttataacagg tggcatagtc caacctggat ctgtataagt
    11341 tagcggaacc aaacctgatg ccattgctcc ccacgctact agtaagttaa acattggagc
    11401 taagataaat ggaactagta acaaaatgtt caaaacaata ggaacgccaa acattgctgg
    11461 ttcatttata ttaaataatc caggtataac agttataggt gccaaagttt ttagttgttt
    11521 actagctttc ttcttatgtg ctaaatatcc taacgcaaga actaaaccta tggttgcacc
    11581 accgccacct atgaatacaa aattatccat aaatacgcta gtaaaaatat ttggaagagt
    11641 ttctccagtt tgataagcta ctttatttgc atctagatta gctaaccata acggtttcat
    11701 aactgcatta acaacatttc ctccgtgtaa tcctacaaac caaaaactac tattaaggaa
    11761 aattaagata agaagaccaa taacattatt tcctaaaagt ccaagtggac ctcccaaagc
    11821 tacttgagca atttcatgaa gattaggtaa acttaattta tctaaagttg cataaacaat
    11881 caaccaacca acaatagtca ctgcaccagg aataatggca ctaaagcttt tagatactgc
    11941 tggtggaaca ccatccggca tttttatctg tatattatga tttataaacc attggtagat
    12001 atagccatta atcaatccta aaatcatagc aacaaataaa ccttttgatg ccatgaaagc
    12061 ggtaggcatt cctgctccag cctctcctct aatgaaaggc gtaactgtaa taaaagatga
    12121 taatgacaca ataccagcag gaataccatc aactttgtat tgtctagcca taaagtaagc
    12181 gataccaaaa ctagctacaa gaccaagtaa tccaaaacta ctatcaacac ccttccataa
    12241 atagtcagca acaccaatat cacccagata tttttcccat cctggaatag gaaaacttgc
    12301 aataaccatt agtaatgaac ctatcaacaa taaaggtata gttagagtaa taccgtctcg
    12361 aatagaaacc aacgctttat tattacccaa tctagccgct actggaagta acttttcttg
    12421 taataatttt tccataacct tttcctctta aatatatttt attatcaaaa gttatcaatt
    12481 atctttattt tttgacgtca agttgttatt tgattatctt ttgttattta tattttacaa
    12541 ctataagaaa gccttgtcaa ggatttgtgt aaacatttga ttatttttta ttatcaatat
    12601 ataataaaaa gagaccagta agtaatgaaa agcttaaaaa aattaacatc tacatttatc
    12661 catagcaaaa aatcatagga ttttaagaat ctgacaacta ggaagaaaac taatatgacc
    12721 ttatctaaga aacaattaca actaagagct aaaatactgg aaacagttta cacattaggt
    12781 cccatttcac gaattgaaat cgctactaaa acaggaataa cacctgcaac aactagcagt
    12841 atcacaaatg atctgattaa agaaaatatt ctcttagaac ttggtgaaga cgaacacgat
    12901 acaagcgtag ggagaaaaaa aatcctgcta gacattcaag ctaaacgatt ttactacatt
    12961 ggttgtgaac tatctgaaaa acatttcact tttgctttag gagataatct aggaaatatc
    13021 ttaaaggaag agaaagaaat tgttactaaa cagttaatcc aagaaaaggg aaatcaactc
    13081 attaaccaga cactaaagca attcttaaat aactgctctg attatgaaat agaagcaatt
    13141 ggaatcgcgc tacctggtcg ctatttagat aattataaaa taacaacaaa caatccttta
    13201 tggcaacata tcgacttaga aatgattcaa tcccactttg ataagccttt gtttttctct
    13261 aacaatgtta actgtatggc tataggtaaa cgcctattta gtcgccaaca gaatgaccct
    13321 aattttgctt attttcattt tgctagaggt atgcactgtt cttatatcta cgacggaaac
    13381 atttatggga aaggaaatct aatgattgga gaaatagggc atacagttgt ttcatctgag
    13441 ggagaagaat gtagctgcgg gcgcaaggga tgcttacaaa cttttgctgg agaatcttgg
    13501 ttaatcaaaa aatcaaaaat tctatatcat caatctccct attctctact tcctagttta
    13561 gtcaaaaatg ccgatgatat tgatatccaa gttattttaa ctgcttatca attaggtgac
    13621 actggaataa tcacacttat ccatcaagcc ttactctatc ttagtcaaac cattttaaat
    13681 atcagtatga tgattgactc tcaaaaaatc tacctacata gtcctttact aacaaatcaa
    13741 cacatcatcc aaaaactata tagtgaaatg aactacaaac ccaaactgct ctataatcgc
    13801 ctacctgaag tcattattga accttacaat gattttacag ccgcacactc agctattgca
    13861 ctttgtttgt atcatacaat tctacattct taattttcta ttacatttaa taaataggct
    13921 aaaaagaggg agtatatcat aaaaagcgaa taaacctgtt ttctgaaaat cagaattctg
    13981 ttttgttcgc tttctttata tttggaatta tactcctatc tccccttttt cataatgtat
    14041 agtaaaatga aataataaca ggacgaatcg atcgggacag tcaaatcgat ttctaacaat
    14101 gttttagaag tagaggtgta ctattctagt ttcaatctac tatatttttg tacaggtgct
    14161 tcaaccattt gaacgatttc aaatccttct ttttggtaaa gattctgagc tctttgattt
    14221 gcctcgaaga catttagaga aatactatct atatcttcat tttcaaaggc caaactaaca
    14281 aatttcctta aagcctggct acctaagtct tgctcctgtt tctgggggtt gataaaaaat
    14341 ctcccgatat gaagattgct gtcttctagc ctgattttct ggataagtcc cacaaactct
    14401 tgttcatcaa agattgaaaa gactccttcc aaggcttgaa gggtcagtag aaaaggaatc
    14461 cttggtccca tccattgttc ttgaaaggat ttgcctaggg agttggacca ctggcataca
    14521 aattgagcgt tttctatact caccttttct tcaaaacgaa ttgtcatctt ttcctcacca
    14581 tcttatctat gtttctccat tatactattt ctcccatttt ttacgaatag ataagtatga
    14641 ttgattttta tttttttctc gtcgggagca ttctcgcttc ctttcttggt ttggtcattg
    14701 accgttttcc agagcaatcc attatcagtt cagccagtca ctgcgattcc tgtcagactc
    14761 gcttgcgtcc cttagatttg attccgattc tctcacaggt cttcaatcgc tttcgctgtc
    14821 gctactgcaa agttcgctat cctgtctggt atgccctctt tgaattagtc ttaggactcc
    14881 tctttctgct ttactcttgg gaattgcttt ccttggggca agtcgtccta atcaccgctg
    14941 gtttgacctt gggtatctac gactttcacc atcaggaata tcccttactg gtctggatga
    15001 ctttccacct aatcctaata gcttcctctg gctggaatct ggtcatggtc tccttccttg
    15061 ctcttggaat tttggctcat tttatcgata tccgcatggg cgcaggggat ttcctctttt
    15121 tagcttcttg tgctctcgtc tttagcgtaa cggagttact gatcttgatt cagtttgctt
    15181 ctgcgacggg tatcctggcc tttctcctgc aaaagaaaaa ggagagactt cctttcgtgc
    15241 ctttcctctt acttgctgct tgtgggatta tttttggtaa gctactgctt gtctgataaa
    15301 atccaatttc tgccatatgt ccttcatgaa attatttcac agttaaatta taaattattt
    15361 cttttgtaca aagggatgat gttatcaaat cgatctgttc ttctatcttc ttgatactga
    15421 tcaaaaaatt tcatttcgac tgaaaatatt tcgcttataa actgtaaacg aatactttgt
    15481 ttagacatta tagtcgctag actgactaga tgattactca aaacgacgtc cagaatactc
    15541 tttactttgc ttggtttttt aacaaaaatt tgatcatcca aaggttcaat cattttgtaa
    15601 cctttttgcg caatttgacg ataaaagtaa gaatgttgct ttggagtcaa taatcctaac
    15661 ttaaaagctc gatactctaa agcctgtatc gaaacattca aatccgactt caataaaata
    15721 taactatcag gattgctgac acgcttgcca accctctctt caaatttgac taaaaactct
    15781 tcttttggca ataaaaaaca tgatgcaaaa taatttgctt cttgctccaa acgattgcca
    15841 tcttcattca tatctttata tttatgtaaa agaatatgtc ctagctcatg agctaagtca
    15901 aaatttcgac gtacagatga tttattcgtt cccaacacaa tataaggtct tcccaatttt
    15961 gaccatgcgc tataagcatc agcttggcca ttaattaatc gttccacgat atagatacct
    16021 gaacgttcta atttataaag caaatcatga ttatcttttg aaatacctaa tttttccctg
    16081 gcataaagag ccaattcctc aatggattct cccttatgat aagattcact cactacatta
    16141 cttaggtcat gaattataat attaggtata attacaaaac tttcaaaata atcaatcaaa
    16201 ctatctacct tatgtaaata catagtttga atatctattg ttttccgtgt tgctaggtct
    16261 gcatttctaa aggcaattac agaagaatca aatcgaatgc tctcttcttc ctgttcaaaa
    16321 taagttaaat caacatgaaa ttggttggcc aaatgcattt tggttgataa tttaggtttc
    16381 gtttcgttgg actcaaactg ccaaatggct tgttccgtta aattaattct ctgagctaat
    16441 tctgctctac ttaaaccatt taacagccgt aattctttca atacccgacc attaaacatt
    16501 tatatactcc ttactacttt tgaccttctt gtttttctat tcttggaata atttcaaaat
    16561 cttctgtttc cgataattct gaaaaattag gaatatcttg atatttagct tcttcgaaat
    16621 ggtacgaact tgattgaata tactcagaca aatcttgaat caagtgtagc tgaccagttc
    16681 gtgcatcagg cataacaaca tctacagata taatattgtt ttctgagtcc gcctcataag
    16741 ttaaaatcat aaatttttcg atattcgaat ttttagtagc ttgttcaatt tcttgaatca
    16801 tttcatcaga aactaactcc atctgaattg gaaaggaatg actatcttca tcatttttgt
    16861 aggaagaatg ttgattaaga taaagtgtat tcatctgagc gtattcaaat aagtagccac
    16921 tcttattttt ttgtaccaaa ggaaattggt tcgtaagtcg cttcttaccc tttataatta
    16981 acaatacttt cccatatttt tctgtatttg tttcaaattc taaatatccc caagtctgtc
    17041 ctgctaattg taatttatac tcaaacaaat ctgctgatgc aaatgcagta tcaatatgat
    17101 taggtcgcgt ccatgcataa ccattcgaca ctatcattgt ctctcttttt tctagacgtt
    17161 catctacata atctttttgc cctttcatca aagtatctac aattttttgt gcctcaagcg
    17221 aatcaaagag atcctgattc aacataattc ttcctcctcc aaatactttt taatgaatta
    17281 tatcattttc ttaaagaaat tactacaata attatctttt tcttaaagtt ctgtgtcaga
    17341 gtaatttaga aaattatatc ttctatagta aaatcaatta aaaactgaac aaatttattg
    17401 ggaaattcaa atcgctttct gaaaatattt taggaaccgt agtgtaatat tccagattca
    17461 attcactata aaactgacct ttctcctgca aaagaaaaag gaaagacttc ctttcgtgcc
    17521 tttcctctta cttgctactt gtttgattat ttttggtaag ctactgcttg tctgataaaa
    17581 tcctgaatcg gctctccttg gtggagagct tttactattt ttgaaccgac gataacacca
    17641 tctgacaccg cattgaagcg ttccagatcg gcttgactag atacaccaaa acctgtcaag
    17701 actgggatgt cggccacttg atgaagttgc gccaagtgct tgtccaaatc tgcacggtaa
    17761 ttgcctgatt tccctgtcac cccattgatg gcaacggcat agacgaatcc ctccgcgcct
    17821 tcaatcaact ctttctggcg ctcaattcct gtggtcaagc ttactaaagg aatcaaggcg
    17881 atatctgtat ctgccaaaaa tggttctaca aagttggcat gttcatgagg caagtctggg
    17941 ataatcaagc ccttcacagc tgtatcagcc agatctttga caaagttctc cacaccgtac
    18001 tgaaagaggg ggttgaagta ggtcatgatg accagtggaa tctctgtttc aatggttttc
    18061 aaggtttcaa ctaaagcctg ggtagaggtc ccgtgggcta aactgcgcaa gccagcttct
    18121 tcgataacag gtccatctgc aacagggtct gaaaagggaa tacccacttc aattgcagag
    18181 acacccaaat cttctagaaa gtggattgtt tctcctagtc catccaaacc tttctcgtgg
    18241 tctccagcca tgatataggg aacaaaaatt ccttttccag ctgctttaat agcatttaat
    18301 ttttttgtta gtgtcttagg catgagcttc tcccttcttt gctgcatctg cttccaagcg
    18361 gtctttgact tgaaccacat ccttgtcccc acgacctgat aggcagacaa tcatagactt
    18421 ttctggtcca agttctttgg ccaatttcac cgcaaaggcg atagcatggc tagattccaa
    18481 agctgggata atcccttcca cacgagacaa gagttggaat ccttccaaag cttcttcgtc
    18541 tgtcacaggg acatagctgg cacgtttaat atcgtggtag tgagaatgct ctggaccgat
    18601 accaggatag tccaaacctg ctgagataga gaaggcttca agaatttgac catgggcatc
    18661 ttggagcaca tccatgaggg aaccgtgaag gacacctgga caacccttgg tcaaggtagc
    18721 tgcgtggtgc tccgtatcca caccaagtcc agccgcttca gctccataca tggctactga
    18781 ctcatcttct acaaagggat ggaagagacc gatggcattc gacccaccac caacacaggc
    18841 tactagggca tctggcagat tttgtcctgt caagtcacgg tactgttgtt tagcctctcg
    18901 accaatgaca ctttggaagt cacgaacaat ttctggaaat ggatgaggcc ccaaggcaga
    18961 accaagaata tagtgggtat catcgatatt agccacccat gaacgaaggg ctgcattaac
    19021 cgcatccttg agcacgcgcg aaccatctgt cacggcctcg accttagctc ccaaaagctc
    19081 cattcggaag acattgaggg cttggcgttt gacatcttcc tcacccatgt agatggtaca
    19141 ttccatgtta aagagggccg cagcagttgc agttgccaca ccgtgctgac cagcacccgt
    19201 ttctgcgata attttctttt tacccatgcg tttggcaagc caaacttgtc ctaaggcatt
    19261 gttaatcttg tgggctcctg tatggttaag gtcttcccgt ttgagataaa tcttggctcc
    19321 gccgatatgc tgggtcaagt tttttgcgta ataaagagga gtttcacgtc ctacgtactg
    19381 gcgcaaaagc tggtttaatt cctcttggaa acttgggtct gcctgacttt cacggtaggc
    19441 cttctccaac tccaaaactg ctgtcatcaa tgtttctggg acaaaacgtc cgccgaattt
    19501 tccgtaaaat ccatctttat ttggttcctg atatgccatg ctttaccctc tctataaatc
    19561 ttctaatctt ttcatgatct ttttgtccat ctgtctccac tccgctcgat acatctactg
    19621 catagggagt aaaatattga attgctttta ctacattatc ttcattaagg ccacctgcga
    19681 taaagaaggg ctgtgctagt ccagtcgtat ccagttgacc ccaatcaaag ggctggccac
    19741 ttcctgccac aggggcatca aagagtagat aatctgcctg agaattaggg acatgcccat
    19801 ttccatctac ctgcacagcc tgaatactgg cacaaggcaa attctcaaat aaatcatctg
    19861 ccacctgacc gtgaacttga accaagtcca agccaacttt gtcaatcgct tccagcagtt
    19921 ctacccgact tggtgaaaca aatactccaa cctttttcac atctgcagga ataagctttg
    19981 ccaactcagc tgcctcttct aaagtcacct gtcttttact aggtgcaaag acaaaaccga
    20041 tatagtcggc tcctgctgaa acggctgttt ccaccgcttc tttggtcgat agtccacaaa
    20101 ttttaacctt tgtcaatctg caactccttg attctctggg ccacattttc tgcctgcata
    20161 agagctgtcc ctaccaaaat tccgttaaag tatggggcta gtcgttccgc atcctgccct
    20221 gtgaaaatgg cagattcaga aatgtaatag cgaccttcct caaagtaagg ggctaaatct
    20281 acactggtct gcaagtcgac ctcaaaggta gtcaagttgc ggttgttgac cccgataatc
    20341 tcagcaccaa gtctgtgggc tacctctagt tcagctagat tgtgagtctc cactaagact
    20401 tccagaccaa gctctgtcgc gtagtcatac agttccttga ggcgttcttc ggacaaggct
    20461 gccacaataa gcaagataac tgtcgcacct gcattgcgag cgcggatgat ttgcttttca
    20521 tctatgataa agtctttgtt gagcgtcgga atctctacct gactggaaat ttcccgtaga
    20581 taatccaaat gccctttaaa gaaaacctca tctgtcaaca ccgaaatcat cactgctccg
    20641 ttttcttcat aagtctgggc ctgttgcaca atatccacat cgagattgat atctcccaaa
    20701 ctagggctag ctttcttgac ctcagcgatt acctgcaagc agtcctgatg attcttcaaa
    20761 aattctgcca agcgataggt ctggcgcaga ggctggattt gctccagctt catctgctcc
    20821 acctcacgcg ccttctgctc taagattcgt gctaaaaatt cctgactcat ttttggtact
    20881 cctgtaacag tctgagtttt tcaagggcct tgcctctagc aatcacttga cgggccaagg
    20941 caactccttc cttgatgcta tcaatcttac cattagcata gaaaccaaga ccagcattca
    21001 agactgtcgt ttccaagaat ggacttgctt cgtttttcag aacgctaagc aaaatttctg
    21061 cattttcctg agcattccct ccacgaatat cttccatagc atagccttcc attcccaaat
    21121 cctctggagt aaagcttgac aagctgattt cgccattttc aagaagtgca atcttggttg
    21181 ttccgttcaa gccagcttca tccaaccctt ctggtccagc aaccacgatg gcacgtttgc
    21241 gacccatatt tttcaaaacc tgagctgtac tttctaggag ttctggacga ctaattccaa
    21301 gaagctgtgt ttctaaagcc attggatgaa tcagtggacc agtcaagttc ataatcgttg
    21361 gaattcccaa ttccaaacga gctggcatga tgtatttcat agctgggtgc atatttttag
    21421 cgaagagaaa gacgatgcca gttttatcaa agaccttacc tagttcagct ggtttgaggt
    21481 caagattgat tcccaaggct tcgaggacat ctgcggaacc agatttagaa gaaatcgagc
    21541 ggttaccatg cttggccatg tgaataccgc caccagccaa gacaaaggct gcagttgtgg
    21601 aaatattaaa actgaaagac ttgtccccac ctgtaccaca attgtccatg gcatcatgaa
    21661 tctcagttgg aatatgctgg gcatgtcctc tcatgacttg ggcaatggct gtgcgttctt
    21721 caggtgtttc ccccttcatc ttaagagcta agaggagaga agcaatctgc gcttcagtta
    21781 cacgcccagt tatgatacgc tcaatgacat ccgtcatttc cacacctgat aaattttcaa
    21841 attttgctag tttttcaata atctctttca tcctagtttc ctcactttac aacctcctcg
    21901 ataaaattcc gaatagaaga caagccgtct ggcgttccaa tgctctctgg atggtactgg
    21961 aagccataaa tcggtaggtt tttatgttga atccccatga tggtttggtc atcagtcgaa
    22021 cgagctgtca cttcaaagtc ttctggcatt tcctcaatca aaatactgtg ataacgcatg
    22081 accgcacgtc catcctcaat accttgatac aaaacagatg gcgcttcaaa gttgatattg
    22141 ctctgtttcc catgcatgac ttttggagcc aaacctagct taccaccaaa gacttctgca
    22201 atggcttggt ggcccaaaca aatccctaga atcggcttct tgcctgcaaa atcacgaatc
    22261 atgtcttcca tctttccagc atcaactggc caaccaggac caggagaaaa gaccagacca
    22321 tctgcttttt cagcttcttc atacagcttg gaatcatcat ttctcagaac ctgaacttct
    22381 gcaaaattcc caatgtattg ggccaagtta taggtaaaag aatcatagtt gtcaatcaat
    22441 aaaatcatgg tcttagttct ccaattctag tcatagattt tgctttgtta atggtttctt
    22501 ggtattcgtt ttgggcgata gagtcgtaga caatccctgc cccagcctgc acataggctc
    22561 tttgattttt gagaatcatg gttcggatgg cgatggccaa atccatatca cccgtcgcag
    22621 acaagtagcc gattgcccca gcgtatactc cccgtttttc cgtttccagt tcatagatgc
    22681 gtctcatagc tcgaattttt ggtgctccag aaacggttcc agcaggaagc gttgctttca
    22741 aggcatccat ggcagtgagt tctgcaagca aacgtccctt gaccacactg gtcaaatgca
    22801 tgacgtagcg gaagagctcc acctccatat acttagtaac ttggacactg gccgtttcag
    22861 agatgcggcc aatatcgtta cgccccaagt ctaccaacat tcgatgttct gctgtttcct
    22921 tctcatcaga gaggaggtca gtcgccaagg ccttgtcttc ttcatccgta gcccctcttg
    22981 gtcgcgtccc tgcaatcgga ttggttgtca cgatgccatt tttgacagaa accaaacttt
    23041 ctggactagc tccgatgatt tgataatccc caaaatcata gaaataaagg taattagatg
    23101 gattagtcac gcggagattt ctgtagaagt caaatggatt tccagtaact tctgctgaga
    23161 aacgctggct gagtacacat tggaacatat ctccgttacg aatcaagtca cgagctgttt
    23221 ctaccattcc ctcaaactta tgtggagcga tatgcggttt gaagtcaagt ggtgataaat
    23281 ccaagtcttc aaattcattt ggagcaggaa tgcgtaattc ctcaagcact tggttcaagg
    23341 atttttccaa ggcctcttga ctgcgctcac tataaagtgc atcctctatg acatgtatct
    23401 tctccttctt gtggtcaaag accatatagc tctcatagac aaagaaatgc atgtctggcg
    23461 tcccaattgt atcctcaggg atttgaccaa tttcttcata aagcgaaatc atatcgtaac
    23521 caacaaaacc aatggctccc ccaccaaaag ggaggtctga atggtgctgg ctcttatgag
    23581 tcacttcata aaggaaatcc aagggatccc gatcaatcac ttgaccattt tgatagagaa
    23641 ctccattttc aaacttaatc tcaaaaactg gattataggc taggatagaa aaacgagccg
    23701 tttccttgtc tctcggaata ctctctaaaa taaccttatg ttgccccttt aagcgcatat
    23761 aagccaagat tggtgataag acatctccat gaatgattcg ttccattgta atttcccttt
    23821 cagttctaat tctagttcgt ggcgactgta tgaaaaatcc ccacgcaaaa taacttgcgt
    23881 gaggacgaaa ttcgcggtgc cacctcaatt ataggatttc tcctatctct cattcctgtc
    23941 tcagatacct cctgtaacag gctgtgcgat aaagggcact cccttgagaa tgatgttttc
    24001 ttctctcgtt tcagatgaac ccaactttac agctttctct gcttgttttc agcaaccaca
    24061 agctctctgt gagagaaaag actgtaattt ttccatctat tattttttag cttctagtaa
    24121 tctgcaatcg cagctaggtc cttgcctcca cgaccagaga cattgatgaa gagatgttca
    24181 tctcggtaca cctttatact cttcgaaaat ctcttcaaac cgcgtcaacg tcgccttatc
    24241 gtaggtaacg acggatagaa aaaagcccac acacagaata tacttccgtg tgagggcgtt
    24301 ggtaacgcgg tgccacctca attataaagg gactatccct ttacatctct gccttgttta
    24361 acaacaagct gcactgtaag gtgtgcgcac cgaattttca ttgtttcaaa ttcattttca
    24421 aaatcagccc actttcacta cttccaacca cctattcaca atcaccacag gctccctgaa
    24481 gatcaaaaat agttactttt ctgatttgtt gaacttattt taatactttg ttttttcttt
    24541 gtcaagactt ttttacgatt tttttgatat cattcgaatg tgaccatatc ttccttagat
    24601 cgaacatgaa catgtcccac ttgttagaaa ttggatccaa ctcaatagaa actgaatgga
    24661 ggctaaacag aacttatttt agaacactcc atcttttcca ctaggatttt caagaattaa
    24721 acaatactag aaactctgtc tcctaacaaa tttaggagaa acttcaacag atgtgacact
    24781 ttccccttta ataattgcta aaacaccttc tatcatttct ttagccaatt taacataatt
    24841 gggagcaatt gtagacaaag ctggagtata atactgagaa ataggaatat tatcaaatcc
    24901 aatgatagaa atatcatctg gaataagaat tcctttctca tagcacgcac gaatcaagcc
    24961 ctgaaccttt tcatctcctg aaacaaaaat aatgtccgga taattttggg tagtcaagtg
    25021 ctgcattgca taagaataaa ctgaatcaat tgtagataag ccataaatga cttttaaatc
    25081 cataaagtaa tttttatcat tcagaaaaga acgcacacct ctttcacgat ccttattaac
    25141 atgagattct cctcccataa gcaaccacat atttttaaat ttttcttcag ttacagcttt
    25201 catcatatca taagtagctt gaaaattatt attagataca tagactactc cagacgtttg
    25261 agattcaccg aaaacaagaa aaggcatatg gttcttcttt aaatactgaa ttctgatatc
    25321 atctacactt tcataaaaaa caataacacc atctactagg ctacctgtgc ttgatataat
    25381 tgaattacta attgtatcct cctctccaaa gtactcaact atagcattaa caccaaattc
    25441 tttacacgtc cgtaacactt tatctaacag cgtatgaaac caaattaaag gaaaagagtc
    25501 gatttttttt acagaaatca atatatttat agcttctttt ttagttaaat tttttgcata
    25561 cgcatttgga atatacgaca attcctctat aactttttga atcgcttgat aagtttcttc
    25621 tttaacattt actccaccat taataactcg tgaaactgtt tttggagaaa aacctgataa
    25681 acgtgcaata tcataaatag ttaccttttt cccatttata tttttcattt cagtcct
//
LOCUS       DAVKUR010000026        25315 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKUR010000026 DAVKUR010000000
VERSION     DAVKUR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25315
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.026"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(174..545)
                     /locus_tag="VW749_001228"
     CDS             complement(174..545)
                     /locus_tag="VW749_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0175266.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1303..1623
                     /locus_tag="VW749_001229"
     CDS             1303..1623
                     /locus_tag="VW749_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0175267.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILFHLKKEVEIYYQ
                     AKER"
     gene            complement(1912..2382)
                     /locus_tag="VW749_001230"
     CDS             complement(1912..2382)
                     /locus_tag="VW749_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0175268.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(2348..3154)
                     /locus_tag="VW749_001231"
     CDS             complement(2348..3154)
                     /locus_tag="VW749_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0175269.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3370..4011)
                     /locus_tag="VW749_001232"
     CDS             complement(3370..4011)
                     /locus_tag="VW749_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175270.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4008..6116)
                     /locus_tag="VW749_001233"
     CDS             complement(4008..6116)
                     /locus_tag="VW749_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0175271.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6168..6455)
                     /locus_tag="VW749_001234"
     CDS             complement(6168..6455)
                     /locus_tag="VW749_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0175272.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            6880..7200
                     /locus_tag="VW749_001235"
     CDS             6880..7200
                     /locus_tag="VW749_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0175273.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(7253..7825)
                     /locus_tag="VW749_001236"
     CDS             complement(7253..7825)
                     /locus_tag="VW749_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0175274.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8067..8738
                     /gene="sdaAB"
                     /locus_tag="VW749_001237"
     CDS             8067..8738
                     /gene="sdaAB"
                     /locus_tag="VW749_001237"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0175275.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            8747..9619
                     /gene="sdaAA"
                     /locus_tag="VW749_001238"
     CDS             8747..9619
                     /gene="sdaAA"
                     /locus_tag="VW749_001238"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0175276.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9641..10273
                     /locus_tag="VW749_001239"
     CDS             9641..10273
                     /locus_tag="VW749_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0175277.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            10323..10400
                     /locus_tag="VW749_001240"
                     /pseudo
     CDS             10323..10400
                     /locus_tag="VW749_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10666..12516)
                     /locus_tag="VW749_001241"
     CDS             complement(10666..12516)
                     /locus_tag="VW749_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0175278.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(12558..13715)
                     /locus_tag="VW749_001242"
     CDS             complement(12558..13715)
                     /locus_tag="VW749_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0175279.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            13773..14939
                     /locus_tag="VW749_001243"
     CDS             13773..14939
                     /locus_tag="VW749_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0175280.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15078..15404
                     /locus_tag="VW749_001244"
     CDS             15078..15404
                     /locus_tag="VW749_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0175281.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            15391..15984
                     /locus_tag="VW749_001245"
     CDS             15391..15984
                     /locus_tag="VW749_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0175282.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            15977..16888
                     /locus_tag="VW749_001246"
     CDS             15977..16888
                     /locus_tag="VW749_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0175283.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            16951..18015
                     /locus_tag="VW749_001247"
     CDS             16951..18015
                     /locus_tag="VW749_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175284.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(18193..19053)
                     /locus_tag="VW749_001248"
     CDS             complement(18193..19053)
                     /locus_tag="VW749_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0175285.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFERVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(19328..20314)
                     /locus_tag="VW749_001249"
     CDS             complement(19328..20314)
                     /locus_tag="VW749_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0175286.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEREQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINTLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(20586..22061)
                     /locus_tag="VW749_001250"
     CDS             complement(20586..22061)
                     /locus_tag="VW749_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0175287.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(22271..23194)
                     /locus_tag="VW749_001251"
     CDS             complement(22271..23194)
                     /locus_tag="VW749_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0175288.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(23208..24137)
                     /locus_tag="VW749_001252"
     CDS             complement(23208..24137)
                     /locus_tag="VW749_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0175289.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(24456..24676)
                     /locus_tag="VW749_001253"
                     /pseudo
     CDS             complement(24456..24676)
                     /locus_tag="VW749_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24630..24890)
                     /locus_tag="VW749_001254"
     CDS             complement(24630..24890)
                     /locus_tag="VW749_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175290.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         7698 a         5446 c         4495 g         7676 t
ORIGIN      
        1 cactgattgc tatcaatatt tcaattggta aaaaatagta attccaaata aaatgagaaa
       61 tcagcaatga tagaaaaata acaatatcaa ttttcctgtt gttgacatac tctgtaattt
      121 tatgatacag gaatgcaaca ataactgaaa ttaaaacaat caacataaga ttattaacct
      181 attctcaatt gattatcacg tcgcccatcc cagccatcaa taatattggt aaaaatccaa
      241 tcagctccag caccaattcc agcagatgca atacttctaa taacagtatt tgcaaaagca
      301 tttccaatat gaattcctaa tactcctaaa cctttaacaa tcccagctac cagtgcggag
      361 cgtaatccat aagatgcaag aactagttga aggcctccac ctcctgctgc tgctaatgct
      421 gcatatgctg caccagtaat ggctcctgta attgcccacc tgggtatata tatagccccc
      481 ccatcaaggt acatcatctc ttcttcatca atcacaacat aattatttgg taatacaagt
      541 tccatttatt ttctcctttt ttattaagca tgcttaggat ggtttcctaa caagtgatcg
      601 caggctttgt ttagttacct aaattagact tccttccttt atcttatttt aaatatttaa
      661 aaccagttac tgcttgaagc ttaacagttt acttaattca aataacagct aatcactgat
      721 tccctgattt tatcaaatat actaataaca acaattgtga tacgatcatc attataagaa
      781 caacatttaa cgaatcaaag tttttccgag ataataataa agcaacagca agcagtatta
      841 ttactaaaga ttgaataact actattactc ttaacatttt atcctccact aacaactcaa
      901 gctcccttac attatatcga ccagccccat ggaaagatta tagctagact aatcaatgat
      961 ataatacata ctagaataca aaatattttt ttattcatac tttttctcct atctttattt
     1021 tctacctaca tcatacctct tattaagctc atttcaaaat tacgttaact tttttcacga
     1081 aaaggagaca attatgcgtt atgattatgg atagcgcttt caaattttta aactcctatc
     1141 ccatcctttt atctatatta tgagcgaaaa tataataact gtcaagtaac taaagtgaat
     1201 tttataaaaa aattacaagc caaatttgta aagtttacac taagccgcta gggcaatcgt
     1261 ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc
     1321 tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
     1381 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag
     1441 gacgccaaga ataagaaaag ctacgatagg ctggctatct gctatgtccg tattgggatt
     1501 tgtagggatg atgcgaaact tatccaaaaa gggttctccc ttctggagct aaccgaggaa
     1561 acttctatac tgtttcatct caaaaaagaa gtagagatct attaccaagc gaaggaaaga
     1621 taaaaaagcc gagggatttc ctcgactctt tacatattat ttgttcgtta gttcttaata
     1681 ccagctattg ttaagccaga agtttttagc tctgccaagc cacatagtgt gtttactact
     1741 atgtgtccat gtcaccatga atcgccgaac gatttaacga gaaagtatga cttttccgtt
     1801 tatcccaact caattatgac atttttttca aaagtcaata tatctcactt tttcaacgac
     1861 aagaaagagg ctgataatct accaacctct tattctgaac ccatcactcc atcacttttt
     1921 agcttcattc gctttcttag cgactgcaat ctggtattcg acttggtcat tccccttacc
     1981 ggtacaacca tgagcaattg tagtcgctcc tatctgatgc gctatttcaa ccaatttttt
     2041 agaaatcaga gggcggctca aggcagatac caagggatac ttttgttcat aataggcatg
     2101 tgactgaaga gccactagca cataatctgt agcaaattcg tccttaacat caatgacata
     2161 agattctact gccccaacct taagagcctt atcatggatg aaatctaagt ctttcccttc
     2221 acccacatcc atacaaactg aaacaacatc atagtctttc tttaaccagg taatagcaac
     2281 tgatgtgtcc aaaccgccag aataggccaa aattactttt tctttactca tgttcttttc
     2341 cttctttcta tttttcaatg gatgctttaa aggcatcctc aatgagtttg tctaattccc
     2401 cagactcctt caacttttga atggttttat cgactgcctc tttcaattcc ttgctatctt
     2461 ttttcatggc taccgcgtag gaatcatctt gctctttttc aaaattgagg tctgcgattg
     2521 ctaaatcagg attattttcc acaaatccct tggaaacagg ttcttcaaag ataacggcat
     2581 ccacttgtcc tgattttaaa tctgtgatta aattcccatt tttaggcaga gatacgaggg
     2641 aagaattttg tagcaaatct ttcgccatcg tctcttgaat cgaacctttc tgcgctccaa
     2701 cctttttctg cgccaagtcg tttacagact gataagtagt caagtcagat tttttgacaa
     2761 tgagtttatt ttttgcagta tagtagggaa tggaaaagtc aaacaccttg ctccgttcat
     2821 ctgtcttaga aacacctgat atggcaaggt ctgcttttcc tgattgaaca ctagccagta
     2881 cattatcaaa actcatggga gatagttcca attcgacacc tagttctgtt gcgatagcct
     2941 tggctaattc gatatctgaa cccacaatct gatttttccc atcaaccact ttttgatatt
     3001 caaatggagc aaaatctgga ttgagggcta caaccaattt tcctttggac ttgatggctt
     3061 caattccagc cgattgattg ttactacaag caaatagtag ggggagcatc actaaaccaa
     3121 acatcgtcat caacaccttc ttcatcttat tcataacaaa gccttcttta tgtttattct
     3181 tttttattgt ataaataata ctcctatact catatactca tcctttgtca agcctaaatt
     3241 gaaaaaattt tcaatttgaa acaaaaaaaa acctagaaat gctacataaa atgtcattcc
     3301 taggcgtatt tatgctattt ttctctggaa aacatgagta ttcagccagt caaaaggagc
     3361 tgaatgaact cattttccct cgcccaattc aatgacacga tgacattgtt gggctacata
     3421 agcatcgtgg gtcacaataa tgactgtttt cccttctcga ttcatctcta agagaaactt
     3481 caagaccaaa tctctatttt caggatccag cgaacctgta ggttcatcgg ctaaaatcag
     3541 ctggctgggt tttaagatgg ctctagcaac tgcaattcgt tgttgttcgc ccccagacaa
     3601 ctcggagacc ctttgatgca aagtagctga caaacctact ctctctaaaa tctcttccac
     3661 ctttttgagc ttgtctttct taggcaattt cacatatttc agcgccagca tgagattgta
     3721 ctcgaccgtt tcatcatcaa tcagggcaaa attttgaaac agataagaga tatgttcacg
     3781 gattattgtt tgcgacttag cagaattaac cgctagattt gtctgaccaa aaatctcata
     3841 ccgtccgcta taatcaccat ctatcaaacc caataaattt aacaaggtcg acttcccact
     3901 accactctta ccaacaatag ctaccaaatc cccctgatca atcctgagag ataagttatc
     3961 caaaatcact tttcccccaa tggttttggt aatatttttc aactcaatca taagatgccc
     4021 cctttcaata actctactag acttcttttc tccatcctag aagctaagcc tagcacaaat
     4081 agtatatcca gacatgtaaa acctgcaaac agtagaagtg gtaagaacgc atgggcaaag
     4141 aaaatcaaga ctagaagagg gaaactatag cccagcaaga gcagaacgag gagaggacgg
     4201 tagcgatcga ccagtttcca ccccataaac ttcttggtaa tgatatccct gcgcttcaat
     4261 aagaaagttg ttactagtaa gaagtaggaa atcatcatgc taaggagacc aaacaaagca
     4321 aagagtaggt taaaattccg aacagcatct ctataagaat ccactttctc ttgttgaatg
     4381 gcttgaatag atgaaaattt taaataattt ccatctgaca atttctcaac taactctgta
     4441 atctcttttt gatgttgaac cgtattttca attttaatcg gattatttaa gccagttgtt
     4501 gacagggagg ctttctcatc ccacatcata tcagaatcat tgaccaagct aataattgga
     4561 ttggagagat tttcctttcg cttatcacta tatgggaaaa atgaccaatc tccttcataa
     4621 taggcaatct cgacatccat ctcctctatc gttcgttttt gctgctcttc atacttcatc
     4681 gaatgaaagg caattaactt ccccaagagc tgatttttat cttcttcacc tttcgtactt
     4741 gctggcatca aaataacttt tttaataccg gtatctggta gcttgaatcc cttgctcttt
     4801 agaaaattgc gattggcata gtaaacatcc accgtatctg ttaactgata ttgctgaatc
     4861 tgttctgatt ggacaaaatt ttttacagga agactgctac tctgcacata gcccgcctgc
     4921 gttttttcta ccaaatcctg ataaaatcga tagaaataat ctgtagattt ccctgaccct
     4981 gctagctctt cttgccacag attatcattg agtttgaagg tttctaaggt caggtaatta
     5041 ccttgactta cccactgttg ctgataagca agttctttgt tttcttgttc taaacttctg
     5101 cccaccccaa tcagtaaggc cgtcagtaaa atagttgtcc ctattttcat cacataattg
     5161 aagataagac caaatttgaa agatgaaaaa cctttcagca gagagctgat tgtcattttt
     5221 tggattaaga ggtaagtcaa ccaactgata aagagataaa gctgcaacag caaaaaatga
     5281 gacaaccaca gcataggaaa caaatctttt ggcttataat caagcaagaa aaacacgcct
     5341 agattgatca caagagcccc acctaggagg aggtaaaggt tgccttttac aacatcagct
     5401 aaaacagccc tatcttgaaa accaagtaat ttttgtaccc caactctttt catctccatc
     5461 atcggttgat acactgtcac taacacaaga agcaaaatag ccaagacaaa aacaatggca
     5521 gataaaagca aatctcgatt tatgacttcc actgcacttt tgtaggtcgg ctctagcaag
     5581 gtagcctggt ctatcttgaa aaaatcgctc catttctgta caatcctatc cttgtccatc
     5641 tcttgtgtag aagttatcgt atagcgacca tttaaactac gagatgtatc cttgatatag
     5701 gtttgaaaag tcataagctg aataggtttg gcttttagaa aggtcggaat cgtaccaagt
     5761 ttattggaaa tttctttatt actatagact ccttcaccat ctgtggtaaa atcaagagaa
     5821 gaaatcccaa actcttggta ggggaaggta tctttatcaa aaacaccaga cttgaccacc
     5881 tcatcaccac tgtctgtttt gatgatggag actttatact cctttgatac atcctcaaaa
     5941 aatcgaagaa cagacgctgc aggttcgtta atatctttca aatacaaatc caaagaatct
     6001 acagtctttc ccatttcttg aatccgaacc acttctcgtg tatagtttac attaaaaaca
     6061 aaaaaagtgg tacacagaag caggagtaac atacagaaat tactgatttt tttcataaaa
     6121 gtgcctccac tacagttttc cctctccaaa taggagaggg aagaatttta ctcaaatcca
     6181 tagaaatatt ccattcctgt tggcggaatc ttggtgaggg aagctctagc ccatgcctca
     6241 ggttttgcat aatccttaga ggttctaccc ccatgtctaa cagttgctgt atgatatcga
     6301 gtagaatgta agtaatcaga atatccaaaa gttcctgtcc aacctactcc atagttccat
     6361 tgaccaccct caacccatac tgctaaagca tttgtagtag caagtatacc acataccatt
     6421 aaagatgcaa caccaatttt aactaatttt ctcatgattt atttctccta ttatcgagag
     6481 ctgttccgta aaaacagcta tagtaattta tcaacaagta tcgtagtcca ttggactcac
     6541 cttccttcta tctcatttca ttttttaaca acgaacttac tcttaaccgg gagaatggtg
     6601 cgcttctgta tcaggtcctt gaacaaccag agtagtatta agcacactct aactattact
     6661 caagaatcag tccaataaac aatatggata gcgctttcaa atttttaaac tcctatccca
     6721 tccttttatc tatataataa gcgaaaatat aataactgtc aagtaactga agtgaatttt
     6781 ataaaaaaat tacaagccaa atttgtaaag tttacactaa gccgctaggg caatcgtcta
     6841 tcagaatgtc cgtttatttg tcaataatcc gagaaaatct tgcaacgctt agaagtctat
     6901 aaaaactatc aacatttata tgacttgcga atagcaatcc tgctaaacct ttccacactc
     6961 tatctataca atcaagataa aaacatgtgt aagcaaatct gctacacttt actggaggac
     7021 gccaagaata agaaaagcta cgataggctt gctatctgct atgtccctat tgggatttgt
     7081 acagataatg ctaaacttat ccaaaaaggt ttctcacttc tggagctgac cgaggaaact
     7141 tctatgctgt ctcatctcaa aaaagaagta gagacccatt atcaaccaaa gaaattataa
     7201 aaaaagtcga gggagctcct cgacctttta catattattt gttcgttagt tcttaatacc
     7261 agccattgtt aagccagaag tttttagcag cagtccatga accgtaacgt cctgcaacgt
     7321 aggcatctgc tacacgttct tggttttcag ctgagtagtc accgttcagg tatgaatctg
     7381 ttaattggta acgtccgata taacgtccat ttgtagctgt atagctacca cctgattctt
     7441 tttgagcgat ccattctttg gcttctgctt cagatccgct tacagttgaa acaactgttt
     7501 cacttactac tggagctgaa acagtttcat cttgagcggc tggtgccgca taagtagctg
     7561 gcgctggtgt tgcaacaggc gctacagggc catcgataac caactcttga tcaacataaa
     7621 tcaaatgaat gttatcaatg tggttgtttt ctgccaattt ttcaactgtt gtgttgtgag
     7681 tttcagcgat ttctgaaagt gtatcacctt ctttaacagt gtaagttgat gattcttgag
     7741 cagatacaaa tgatggagca aatactgcaa acaaggcagc tactcctgca agagttgctt
     7801 taatcttttt agttattgat ttcatattcg aaaattctcc ttctttctat agttctatca
     7861 taccctttaa atattaccgt ttcttgacac ttttatgtag aaatattaca aaattatttt
     7921 ttatttccct aaataaggtg ttttttgtca taaaagatac tatttttatg ctatttgagg
     7981 tattagaaag gttttcatcc acaattaaag ccaagcccct cattctttga tataatagag
     8041 ataagaattt ttataagggg aaactgatga aatcacttcg ttttcaatct gtctttgata
     8101 tcatcggacc agttatgatt ggcccatcta gtagccatac cgctggtgct gttcgtattg
     8161 ggaagattgt ctcttccatt tttgatgata ctccgacaga agttgaattc caacttttta
     8221 actcatttgc caagacctat cgtggtcacg gaacagacct agcccttgtt gcaggtattt
     8281 taggaatgga tacagatgat cctgaaattc caaatagtct ggaaattgcc cacaagcgtg
     8341 gtatcaagat tgtctggacc attcagaaag acagcaatgc ccctcaccct aacaccacta
     8401 aaattactgt taaaaatgcc cacaagacca tcagcgtgac tggtatttct atcggtggag
     8461 gaaatattca ggtaaccgaa ctcaatggtt ttgccgtctc tctcaatatg aatacaccga
     8521 ctatcatcat cgttcatcaa gatattccag gtatgattgc ccttgttaca gaggcgcttt
     8581 cccgctatgg tatcaatatc gcccagatga atgtcactcg tgaaaaagct ggtgaaaaag
     8641 ccattatgat tatcgaagtt gacagtcgca actgtgatga ggctatcgaa gaaattcgaa
     8701 aaatccctca tctccacaat gtcaatttct ttaaatagga ggaagcatgt tttattctat
     8761 caaagaattg gtcgagcaag cagatctaga ctttcaagga aatgtcgcag aactcatgat
     8821 tacaacagag tttgaattga ccggtcgcga acgtgaagaa gtcttccttc tcatggaacg
     8881 caatctggaa gttatgaaag cctctgtcca acttggcctc aatgaaaata aatctcgtag
     8941 tggcctgaca ggtggagatg ctgccaaatt ggatcactac atcgaaaacg gaaaaactct
     9001 gtcagattac acgattctct ctgctgcccg aaatgccatc gcagtcaatg aacacaatgc
     9061 caaaatgggc ttggtctgtg ccactccaac cgctggaagt gctggctgtc tgccatccgt
     9121 tctcactgct gctattgaaa aattagacct cagccacgag caacaattgg atttcctctt
     9181 tgctgctggt gcctttggac tagtcatcgc aaacaatgcc tccatctcag gtgctgaggg
     9241 tgggtgtcaa gctgaagttg gttcagcctc tgctatgagt gctgccgcct tgactctggc
     9301 tgcaggtgga acaccttatc aggccagtca agctattgcc tttgtcatta aaaatatgct
     9361 aggcctcatc tgtgaccctg ttgcaggttt ggtcgaagtt ccctgtgtca aacgtaatgc
     9421 catgggagct agctttgctt tcatcgcagc agacatggcc ttggcaggta tcgaatctaa
     9481 aatccctgtg gatgaagtga tcgatgccat gtaccaagta ggagcaagca tgccaactgc
     9541 ctttcgtgaa acagctgaag gtggactcgc taccacccct actggtcgtc gcctccaaaa
     9601 agaaattttc ggagaataag cttatcaaat aggagaaacc atgacctcta tcacagcgat
     9661 ttttttcgat ttggatggaa ccctcgttga tagttctatc gggattcaca atgcctttac
     9721 ctataccttt aaagagctgg gggtgcctag ccctgatgcc aaaactattc gtggttttat
     9781 gggaccacct ctcgaaagta gttttgcgac ctgcctgtcc aaagaccaaa tttctgaagc
     9841 cgtgcagata tatcgttctt actataaggc aaaaggcatc tatgaagctc aactctttcc
     9901 tcagattata gacttgcttg aggagttatc gagcagttat ccactctaca tcaccacgac
     9961 aaaggataca tctactgctc aagacatggc aaaaaacttg gaaatccatc atttctttga
    10021 tggcatttat ggttctagcc ctgaagcacc ccataaggca gatgtcattc accaagcctt
    10081 gcagacacat caactagcac cagaacaagc catcatcatc ggagatacca agtttgatat
    10141 gctgggagct cgagaaacag gtattcagaa attggccatc acttggggat ttggagagca
    10201 agcagatcta ctaaactatc aacctgatta tatcgctcac aaacccttag aagttttggc
    10261 gtattttcaa tagcatagac tgggtaacaa ttccatttca gaagaaaatg aagtaatact
    10321 caatgaaaat caaagagcaa actaggaaac tagctgcggg ctgctcaaaa cactgttttg
    10381 aggttgcaga tagaactgac gaagtcagat caaaacactg ttttaaggtt gtggatggaa
    10441 ctgacgaagt cagatcaaaa cactgttttg aggttgcaga tagaactgac gaagtcagat
    10501 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat atacggcaag
    10561 gcgacgttga cgtggtttga agagattttc gaagagtata agtctctaca taataaaacg
    10621 catattacca aggttgtgta actggatact atgcgttttt cttttttatt caatgtgggt
    10681 tgtttgatta gcaaaggcga taatagcttg cttcaactca tctccactga gagtgcggaa
    10741 ctctccaatc ttttgattga tggattctaa aggcatgaca ttaaccttac caacgaaaat
    10801 cttatccata acttgattat caacgagttc ggttgatacc aagagttctt cgtagagttt
    10861 ttcacctggg cggattccaa cttcaacgat tggaatttca ctttcagtgt ggccacttag
    10921 aagcaccatc ttcttggcca agtcataaat cttgactggt ttgcccatat caaggataaa
    10981 gacttcccca tctttggcat aagcaccagc atggataacc agacggctag cttctggaat
    11041 ggtcataaag taacgggtca tgcggaagtc tgtcaccgtt acaggcccac cttcagcaat
    11101 ctgacgttca aagactggaa tgacactacc acggctacca agaacattcc caaaacgaac
    11161 tgcacagtag gttgattggc tacgttggtt aaagccagtg acaatcaact ccgccacgcg
    11221 cttggttgct cccataacat ttggtggatt gactgcctta tctgtcgaaa tcataaccat
    11281 cttagacact ttagcttcat caacagcctt agcaacattg taagttccac ggatattgtt
    11341 tttgaaggct tcttttggat tgcgctccat cataggaaca tgcttgtggg cagccgcatg
    11401 ataaacaata gcaggtttgt actgctcaaa gacttgcaac aaacgatcat agtcttgaat
    11461 gtccgcaatc acaggtacat aatcaatccc ttggaactta cgaatcaatt catgataaac
    11521 aaggtagatt gagttttccc catgaccgag caagacaatg cgttcaggat tgaagcgact
    11581 aacttgacga cagatttcag aaccgattga acctccagct cctgtgacta agatggtctt
    11641 acctgtcagt tctgcaccca gacgcgattc gtcaagacgg atttcctgac gacccaaaag
    11701 gtccgtaata tcaatttttt ggaagccagt acctgcttgg tgaaggccct gaacaacagt
    11761 ttcaacctta ggcatcttgt aacatttgac acccagctta ttacacatct gcaagatacg
    11821 ctcatattct gacggatcca gcgacggaat cgcaacgatg acacgctcga tttgatggcg
    11881 tttggctaat tcaggcagat tgtcataaga gcccaaaaca ggaataccac caagtttttg
    11941 accctttttc ttagaatcct tatccaaaat accgaccagt tctaattcac tggttggatg
    12001 ttggtaacta tccataaaga gagccccacc atcaccggca ccaatcaaga aggttcgacg
    12061 gtgttctcca tcaccactac cttttttgcg tctggagtag attaactgcc aagtaatccg
    12121 tggcaataaa atcaagaagg tactcaacaa gataaagaga atgatgaaac ggatggagaa
    12181 gagtggcaag aaggcataac agatactata tgacaagaca ctgctagcag tcacaccaaa
    12241 aaagattttc atgaaatccg taatcttgct gtaacgacta atgctcgcgt tcaaccccca
    12301 aaaaccaatc atcaattgat agaacaggaa ggccaaactc gtatagataa tgtagtcaac
    12361 aggtgctgga ttaatcagcc cataaaataa aatataagat acaatgatgg aaaccaccat
    12421 actgaaaata tcaaatattc cccagaaaac ctgcttttgt tgtttattta aaatttccac
    12481 cagatcaatc acataatctg ttagtttttt attcatagaa atctactcct ccttaaaaga
    12541 gttttactat attgttatta tagcatattt tgatttattt ggcttatttt atccaaataa
    12601 attattgttc tcttgtactc cttcttccat ttaaatcctc taattaaacc tacaatcgtc
    12661 ccaaagccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat tagaaatcca
    12721 tttttatgtt ttaataaagt cagcaaagtg agtaatgaca aaagtagaaa ataggcacct
    12781 aatagtaaag ttatgaatac gaatgtgatc ggtaacaatg ctagactaaa cacaagactc
    12841 aaaacaaata aacaaggaac atagtgaaat aatgataaac acttaaactg aacatgactt
    12901 gtcaagccaa tccacaaacc atttgaatac ttttgatgca gcattttctt gaatgttggt
    12961 cgaatatact gataagatag aatacttggg ctatagcgga ttttataacc atgttctcga
    13021 attctataat gaatatcatt atcttcagtt cggccaagtt gctcatttac taaaccaacc
    13081 ttctggaaaa cctctcgttt atacatccca tgaaaaatag aagaaacata tctatcctcg
    13141 gaactatttc gataattggc aatgctactg ccaaacatat tttcctcaac aagatgcaag
    13201 gtctctgccc attttccttt tccttcgaca atcgtcggtc taggcccccc acagacaaat
    13261 tcaccttgtt gaataatagc cacattgttc attacaaaac tctcagtaac ttttgaatga
    13321 gcatcaattt ttaaaataag gtcccctaca gaatgtttaa ctcccaggtt aaaaccacta
    13381 gcttgatttt tcttaggatt gttatacaat ctaattgagt taaactctgt atcttccttt
    13441 ataaattgct gaatgatagc tgtggtccca tctgtggaca tagcatttat aaatagaatt
    13501 tcaatatcct ctttaggata ggtttgattt tttaagtctt caattagacc aggcagatat
    13561 ttttcttcat tgtatgcact gattacaatg gatacgagaa gactttcaac attttgagtc
    13621 actactactc tcctgaattt ttccttccac cattctatca taattttcaa gactttccca
    13681 tttttatctt gaaagccaga aaccttactt gacattatag tgaaaaagcc ttaaaataag
    13741 ctgttattaa aatcagctag aagaggtatt atatgaaaaa gcaatcactc ttttttgttc
    13801 caggtattat cctgattggt gtttccttgc gaactccttt tactgtttta cccattattt
    13861 tgggaaatat ttcgcaaggt ctggaggtag aagttagttc gcttggtgtc ttgaccagcc
    13921 tgcctctcct tatgtttacc ctcttttcac cattttctac ccaactggct cagaaaatcg
    13981 gcttggagca tctcttcacc tacagcctct tcttcttgac catcggctca cttattcgac
    14041 taatcaatct gcccctgctc tatctaggaa ccttgatggt tggggcaagt gtcgcagtca
    14101 tcaatgtcct gcttcctagt cttatccaag ccaatcaacc aaagaaaatt ggttttctga
    14161 ccaccttata tgtaacgtct atggggattg caacggctct ggcttcctat ctagctgtgc
    14221 ccattacaca agccagttct tggaaaggac ttatccttct cctcacgtta ctctgtctag
    14281 caactttttt ggtctggctc ccaaatcacc gctataatca tagactagct ccacaaacca
    14341 aacaaaaaag tcaaataaag gtcatgcgta ataaacaggt ttgggcaatt attatctttt
    14401 caggttttca atccttgatc ttttacaccg tcatgacctg gttacctacc atgtctatcc
    14461 atgcaggtct atccagtcac gaagctggct tgctgacttc tatcttatct ctgattagca
    14521 ttcctttttc aatgaccatc ccaagcctga caaccagttt atctactcgc aaccgtcagc
    14581 tcatgctcac tctggtttca ctagctggtg tggtcggcat ttccatgctc tttttcccaa
    14641 tcaataattt catttactgg cttgccatcc atctcctcat cggaaccgca accagtgccc
    14701 tcttccctta tctcatggtc aacttttcac tcaagacaag cgcccctgaa aagacagccc
    14761 aattgtccgg cctatctcaa acaggaggct atatcctagc agcctttggg ccaaccctct
    14821 ttggttacag ttttgacctg ttccactctt gggtaccatc tgtagctgcc ctcttgctca
    14881 tcgatatcct gatgactgtg gccctcttta cagtggacag agcggataag atcctttaaa
    14941 cttctagttt tagctagaag ttttttatat ataaaaattt tacacatttc tcttgacagg
    15001 gctttctttt agatgtacaa tgtatgtgta gaaaaattat atataaaaat cttacacatt
    15061 agaaaaggag gtttcccatg tactttccaa catcctctgc cttgattgaa tttctcatct
    15121 tggctgtact ggagcagggt gattcttatg gttatgagat tagccaaacc attaagctga
    15181 tcgctaatat caaagaatcc acactctatc ccattctcaa aaaattggaa ggcaatagct
    15241 ttctgacaac ctactctaga gagttccaag gtcgcatgcg caaatactac tccttgacaa
    15301 acggtggtat agagcagctc ttgaccctaa aagatgaatg ggcactctat acagacacca
    15361 tcaatggcat catagaaggg agtatccgcc atgacaagaa ctgaatacct gactcagcta
    15421 gaactctatc tcaagaaact acctgaagct gaccgtatcg aagccatgga ctatttcaga
    15481 gagctctttg acgatgctgg agtcgaagga gaagaagaac tcatcgctag tttgggaact
    15541 cccaaagaag cggcccacga agttctatcc aatcttctcg ataaaaaaat caatgaagca
    15601 cccgctcaaa aaaataaccg acaaatttta catatcgcct tgttagccct ccttgcagca
    15661 cctatcggca ttcctctggg aatcgccatc ctcgtgaccc tgttcgcaat tcttgtagcc
    15721 gctttgactg tcattctggc tttctttgca gtttccatac tgggtatcat cggcggattc
    15781 ctatttttag ttgaaagttt cactgtcctc gcccaagcca aatcagcctt tatcttgatt
    15841 tttggttctg gtttactggc tatcggtgct tcttcgctag ttttacttgg catttcctat
    15901 gcaactcgct tcttcggtct actcattgtt cgtctggtac aatttgttct taaaaaagga
    15961 aagagaggta atcagcatgc gtaaatggac aaaaggattt ctcatctttg gtgtggtgac
    16021 taccgttatc ggctttatcc tgctttttgt aggtatccaa tctgacggga ttaagagcct
    16081 actttccatg tccaaagaac ctgtctatga tagccgtacg gaaaagctaa cctttggcaa
    16141 ggaagtcgaa aacctagaaa ttactctcca ccaacacacg ctcaccatca cagactcttt
    16201 cgatgatcaa atccacattt cttaccatcc atctctttct gctcaccatg atcttatcac
    16261 caatcagaac gatagaactc tgagtctcac tgataagaaa ctgtctgaaa ctccgtttct
    16321 ctcttctgga attggtggga ttcttcatat cgcaagtagc tactctagtc gttttgaaga
    16381 agttattctc cgactaccaa aagggagaac tctaaaaggg atcaacatct cagccaatcg
    16441 cggacaaacc accatcataa atgctagcct tgaaaatgcg accctcaata caaacagcta
    16501 tatcctccga attgaaggaa gtcgtatcaa aaacagtaaa ctcacaacgc ccaatatcgt
    16561 taatatcttt gatacagttc ttacagatag tcagctagag tcaacagaga atcacttcca
    16621 cgctgaaaat atccaagtcc atggcaaggt tgaactgact gccaaagatt atctcagaat
    16681 catcctagac cagaaagaaa gccaacgaat taactgggac atctcaagca actatggttc
    16741 tatcttccaa ttcacaagag aaaagcctga atcaagaggt acggaattaa gcaaccctta
    16801 caaaactgaa aaaaccgatg tcaaggatca actcattgcg agatctgatg ataatattga
    16861 tctaatatcc acaccaagca gacgttgaca aaaacgctta catttgctac tatggaaaca
    16921 tatttatcta actaaaaagg aggttctacc atgaaacaag aatggtttga aagtaatgat
    16981 tttgtaaaaa caacaagcaa gaacaagcct gaagagcaag ctcaagaggt tgcagacaag
    17041 gctgaagaaa cgatagccga tctcgataca ccaattgaaa aaaatactca gttagaggag
    17101 gaagtccctc aagctgaagt cgaattggaa agccagcaag aagagaaaat tgaagctcct
    17161 gaagacagtg aagcgagaac agaaatagaa gaaaagaagg catctaattc tactgaagaa
    17221 gagccagacc tttctaaaga aacagaaaaa gtcactatag ctgaagagag ccaagaagct
    17281 cttcctcagc aaaaagcaac cacgaaagag ccacttctta tcagtaaatc tttagaaagt
    17341 ccttatatcc ccgaccaagc tccaaaatct agggataaat ggaaagagca agtgcttgat
    17401 ttttggtctt ggctagtgga agcgatcaaa tctcctacaa gtaagttgga aacaagtatc
    17461 acacacagtt acacagcctt tctcttgctc attctgtttt ctgcatcttc ctttttcttt
    17521 agtatctatc acatcaaaca tgcttactat ggacatatag caagcattaa cagtcgcttc
    17581 cctgagcagc tagctccttt aactcttttt tctatcatct ctatcctagt agcgacaaca
    17641 ctcttcttct tttcattcct cttgggtagt ttcgttgtga gacgatttat ccaccaggaa
    17701 aaggactgga cgctagacaa ggttctccaa caatatagtc aactcttggc aattccaatc
    17761 ttcctcactg ctattgctag tttctttgct ttctttgata gcctacgatt tacagccctc
    17821 ttgtgtgtga ttagcattgg aatcattctg cttgccagtc tccatatcat tacaagacca
    17881 agtcaagcaa gtgaaaccga ctccttctat caattattct tgtctgtcct tgtgaacgga
    17941 gttattatcc tcctcttctt tgtagctgaa gtggcactga ttggagatta tcttcgtatc
    18001 ttggcctttc tttaaacttc atactcttca aaaatcaaat tcaaaccacg tcagcttcgc
    18061 cttaccgtac tcaagtacag cctgcggcta gcttcctagt ttgctctttg attttcattg
    18121 agtagcaatc ctgtcatcct tggcaggatt ttttctatgt caaaaaagca agtcgattga
    18181 cctgcttctg ctttactttt cttgtgctaa tgttttaaaa tctttgtcta atatgggttg
    18241 cacttctatt tgattggcgt ctagttggtg gtaaaaagat gggggtaata cctctaagaa
    18301 ttttgcatag tccaagcgag caatggcttc atagtcttct ggtttagagc catctcctgt
    18361 gatttgaacc aagtcaatct cccactggac ttccttatcc accaattgct caatataggc
    18421 tgcaggaaca aacggttctc tcggtaaaac tgtcttgact ccttgagcta gatggtaaac
    18481 gccatgcact tttccttctc catcctgata gaaggaaact ctctcaaagt aggcatctgt
    18541 ctcttgaacc gcacgcacac gcgcttcaaa ctgagccaag ccatctgcct ctaaaaagct
    18601 tttcaagttc tcacgactaa agaaaatagg attaaaaatt ccttggcaaa tcgtaaaacg
    18661 agctacaggg tctgctagat aggcttgaat acttgcttgg aaataagctt caaaatcaaa
    18721 accatctagc ccttcaatat cagtccctgt ataagcaagc aaagcatcta aaaatgactt
    18781 gataatctgc cagtctgtct ttgttagtag gtcaggaaga tcgacacggt aagccttttg
    18841 accatcagca taactgacct taaagagaaa ttgtgattgc cccactatcg cacactcgat
    18901 atattcgaga cgattaagag gctgacggag atagactaca tcatagctat gtgactccaa
    18961 accgtctagc aaggccaaga tcgacttggc attcaaaatc tcttgttctc ctaaaatgct
    19021 ctgtttattt ggaataaaaa atgttttcgc cataactgga ctcctttgaa atcgtttaca
    19081 tacagtatac cttatttttc tgaaagatac aaaaacaaac tttatactct tcgaaaatct
    19141 cttcaaaccg cgtcagcttc gccttgccgt agatatatgt aactgacttc gtcagtctta
    19201 tctacaacct caaagcagtg ctttgagcag cctgcagcta gcttcctagt ttgctctttg
    19261 attttcattg agtattagat ttttgagtac aaagcataga aaaacagccc ctaaggactg
    19321 tttgatctta tacagtagct gcctgatcca agctttcacc gatagcggct aggcgctcaa
    19381 tcacttcagc ttgtgtcaat tcattttttg aaacatagcg gttacgtggg tgaacacggc
    19441 actcgtgtga gcatccacga aggtacttgt cttcattttc ttctgatgtc aagatacgac
    19501 ggttacagaa gggatttcca cagttgacat aacgttcaca tggtgttcca tcaaaccagt
    19561 ctttccctac gatagttggg ttgacatggt tgacatcaac ggcaatacgc tcgtcaaaga
    19621 cgtacatttt cccatcccaa agctcacctt gaacttctgg gtctttaccg taagttgcga
    19681 ttcctccgtg caattggccg acatctttgt agccttcacg gaccatccag cctgagaatt
    19741 tctcacagcg aacgccacct gtacagtaaa ccacgacacg cttgtccatg aatttttcct
    19801 tgttatcacg gacccattgt ggtaactcac ggaagttgcg aatatctggg cgaatagccc
    19861 cacggaaatg tcctaggtcg tactcataat cgttacgtgt gtcaaggaca acggtatctt
    19921 tatcaagaag cgcttctttg aactcttttg gagacaagta agcacctgtt gtttcaagtg
    19981 tgttgatgtc attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt
    20041 agcgaacaaa catcttcttg aaggcttgtt ctctttcttc gtcaatcttg aaccagagat
    20101 cttccatacc tgggaggctg tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac
    20161 ctgaaactgt tccgttaatt ccctcgtcag cgactaggat acggccttta aggccgattg
    20221 atttacagaa agccaagtgg tctgcagcaa attgctctgc attttcaatt ggagtataaa
    20281 ggtagtaaag taagacacga atatcttttg ccataagatt tgttctcttt tctattctta
    20341 aattttctaa attttttatt tatccatact agtatacctg cttgagaaaa cgaatgcaat
    20401 ttatttgact ggaaattgta gagggttctc gaaatttcct gaatggttaa aataaggaca
    20461 agagaaaaca tggatatcta tatccttgtg ccaaaaaaac cactgccctc cccagaccaa
    20521 cctgaggaaa gcagtgattc ttattttagg agttaggaat gaatacacga aatcaattta
    20581 gctgattatt ttttgttttt caagaattca tcgtattgtt tttgcatttc gttcaatact
    20641 ttttcgtagg caccttcaga tttcaatttt tccatcaatt ctggaatagc tttatctggg
    20701 tctacagtac cagtgttgat agctgtatca aattgttgca ttgtgttagc aatagctgag
    20761 atttcagatt tcacattgtc agtattgaag ataaatccaa gcgctggaga ttctttagct
    20821 tctgccaatt ctttcttaga attttcgatt tgttggtctg taacgttttc gttgatgtaa
    20881 aggatccagt tgttaccagt gttccatcca cccatgtgag tgtttccttt gtagccatca
    20941 agaacgcgaa cacggttttc tttaccttca attttttccc agttcttgcc ttctggaccg
    21001 taaacaagac cgttcaagag ttctggattc gtattcaaga ggttcaagat ttccattgat
    21061 ttttctttgt tcttagagtt gtttgagatg acaaagttag caacttgtgt tgtttggttt
    21121 ttcttgatga agttagtaat tggtttgatt tggatatctt tgttggcaac acgtgaaagc
    21181 aagctgttac cgtagtcagc tggtcctact gtttcttcac gaacgaacca agtatcttgt
    21241 tgaaggtcaa aggaagtatc gcttgttgcg acatcttttg gaatgtagcc agcttcatag
    21301 aatttgtgaa gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg gtttacaact
    21361 ttagtagtat cgccttcaag gtcaataacg aatggaagcc cgtttgctac tgggtagtca
    21421 aaattatcag atgggatgaa aactttacca atagcaaatg gtactacgtc tggagctttt
    21481 tctttgattt gtttcaagac tggctcaaga gtttcgtaag aagtaacacc tgaaatatcg
    21541 ataccatatt tggcaaggag agttccgttg aaggcaaagt tttgagatga tgctacgttg
    21601 gctgcaactg gtacagcata aatcttacca tttacagtat tacccttgat ataagctgga
    21661 tcaagtgcct tgtaaaggtc tttaccttct tttttgtaca attctgtcaa gtcagcataa
    21721 gcaccttttt gagcatttac aatatagtta tctgcaaagg cgatatcata gttttcacca
    21781 gatgatgtga taactgacat tttcttacca tagtcacccc agccaaggta ttggatatcc
    21841 aatttggcac caactttttc ttcgatgatt ttgttggcat ttgctaacaa ttcatccaag
    21901 ttatctggtt tgtcaccgat ttggtacatt ttgataacag gtttgtcacc tgaatcagca
    21961 gcttttttac tgttacctgt caagttgcca caagcagcaa gacctgcagc caaagcgact
    22021 acactagcag atgcaaaagc atattttttc cagtttttca tgataaaaac tccttttttt
    22081 atttttaaac ttataaacaa tgtaatgatc ttatactcaa tgaaaatcaa agagcaaact
    22141 agaaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgc ggtttgaatt
    22201 tgattttcga agagtattaa cttcacacaa gggaagttgg gaactgagaa atgttatttc
    22261 tcaataagca ctattctttc acaccaccga tagtcaaacc ttttacaaag tagcgttgga
    22321 aaaatggata caaaatcgcg attggaaggg ttgcaaccac aaccatggcc atacgacctg
    22381 tttctttcgg tagagcaact cccagttgac cagtcaagcc gaccgctttg gcaatgtagt
    22441 ccatattttg ttggatttgc atgagcaaat attgcaatgg atacaagttg tcactcttga
    22501 tgtaaagaag ggcgttgaac cagtcattcc agaaaccaag agctgttaag agcgtgatgg
    22561 ttgcgatacc tggtagtgac aatggcaaac agatttggaa gaaaatccgg gcttcactgg
    22621 caccatcgat acgagccgat tctagaatgg cttctggaat ggtcttcttg aagaaggaac
    22681 gcatcaagat gatgttaaat ggtgagagaa gcattggaac aatcaaggcc caaacagtat
    22741 ccccaagctg aagcacacga gtcaccatga tataacctgg taccaaacca gcgttgaaca
    22801 acatactgag cagaacgaag atggtaaaga atctgcgata cttaaaggtt gtccgtgaaa
    22861 tagcgtaggc ataggttgtt gtgataaaga catttgtcaa tgtcccaact acggttacaa
    22921 agacagagat gaagagggct tgtaggattt tatccttaaa ctgtgccaaa aactcaaaac
    22981 cgtctaagcc aaattgggat gggaagaagc tatagccgta ttggaggagg cttttctcgt
    23041 ctgtcactga aataatgata acgaatacaa aaggtaggat acaagagagg gcaatcaaac
    23101 ccgaaatgat actgaagaag atatctgctt tcttactgaa ggagtgaatg ccgacattat
    23161 caattttttc ttttttaatt ttcttttttg ccatattctc ctcctttcta gaacaaagct
    23221 gagtttggat cgactcgtct tgcaagcaag tttgatagga taaccagaat caaaccaaca
    23281 acggattggt aaagaccggc tgctgcagcc ataccgatat ctgctgtctg agtcaaacca
    23341 ttaaagacat atacgtccaa aacgttggtt acattgtaaa gctgaccagc attgtgtggg
    23401 atttgataga agagaccaaa gtctgcgcgg aagatatttc cgactgcaag gatggtcaat
    23461 acagttacaa gcggagtcaa ctgaggaatg gttacgttgc gaatacgttg ccacttgcta
    23521 gctccgtcca ctgtcgctgc ttcgtagtag gttggatcaa ttcccatgat cgtcgcatag
    23581 tacatgacac tgctatatcc aaagcctttc caaataccta ggaaaagtag gagatagggc
    23641 cagatgccca ggtcagcgta aaaattgact tctttgagac caagactttc caatagatga
    23701 ttgaacaccc ctttatcaat atttaggaag gcatctgtaa agaaactgat gataacccaa
    23761 gacaagaagt aagggaacaa catagaagtt tggaaaatct tcaccattct cttagaacgg
    23821 agctcgctga ggataatggc aatccctaca gatacaacta aacctagaaa gataaagcca
    23881 agattgtaga ggacagtatt tcgtgtgata ataaaggcgt ctcttgaact aaataagaat
    23941 ctgaaattat cgagtccgac ccatttacta tttatgatac tatctatgaa accattactg
    24001 gtcatgtggt agtctttgaa ggcaaccacg ttcccaaata ctggaatgta aaagaataga
    24061 atcaaccaga gtgtccctgg caaaaccatc aagagaaaga tccagttgtc tctcaatgtt
    24121 tttgaaaact ttttcataat ttcctccctt tttattttga tatccatcta aaaattcttt
    24181 tttagacttt tgataacgat tacattatta gtatactcct atttgcaggt taggttaaac
    24241 tcctaattat agaaaaaact ccacaaatta tgtagcagat ttaaaacttt atcaccacta
    24301 tcaaacaaat gtcctaaatc aattgtttat tttatctcta ttagcccagt gatggcgtca
    24361 ctctgttata agcatccaac aacggggtat actgaaaaat ctccagacta gggaactcag
    24421 agatagttcc taatctggag atttttaata tgttattagg cgtttgcttt caacttagca
    24481 ataacctctt taagattatc aatcacctct gcttcagtat gctcagagct ttttcatctg
    24541 ccaagaacaa aactgctttt tgaagttctt tttgagagtt ttcaaggaca tccttatcta
    24601 ctgtttcaag gtttgagtct ttaagaagtt tacttaattc cttggctaat ttcttgagtt
    24661 tgatttgcag actcatcttc tcctgctgtt tctttgcccg ctgtttgtcc tccatcctta
    24721 gttgctgact ggctttcctt aatggactct agggaagcaa tggcatcttt gactgtttgc
    24781 aaaatatcac gtaaaccttg ctctgtcaaa ctatcatctg caaaagcttt cttagcctct
    24841 gccaaaacca gacgtgctga atctgtggta ggattcgata cacctgtcaa tgatctcaaa
    24901 agattttcta aggtttgagt ctgcttacta atactagact aaaatcaaaa agcattatat
    24961 aacagtgata tgaaatcaac taaagaagaa atccaaacta tcaaaacact tttaaaagac
    25021 tctcgtacag ctaaatatca taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga
    25081 acaggacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagatgt
    25141 gtactattct agtttcaatc cattatattt cgtctgatgg gcaaatctta ataaagagat
    25201 tatagagctt ttatagtgat ttgaaataag atgtgaacaa ctctatcagg aaagtcaaat
    25261 taatttatag aaatatttta gcagccaagg tgtactgtta taaattcaat acact
//
LOCUS       DAVKUR010000027        24474 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKUR010000027 DAVKUR010000000
VERSION     DAVKUR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.027"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(258..476)
                     /locus_tag="VW749_001255"
     CDS             complement(258..476)
                     /locus_tag="VW749_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175291.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(722..1000)
                     /locus_tag="VW749_001256"
     CDS             complement(722..1000)
                     /locus_tag="VW749_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175292.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1214..2845)
                     /gene="rlmD"
                     /locus_tag="VW749_001257"
     CDS             complement(1214..2845)
                     /gene="rlmD"
                     /locus_tag="VW749_001257"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0175293.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKIFMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2919..3893)
                     /locus_tag="VW749_001258"
     CDS             complement(2919..3893)
                     /locus_tag="VW749_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0175294.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3967..4581)
                     /gene="pmp23"
                     /locus_tag="VW749_001259"
     CDS             complement(3967..4581)
                     /gene="pmp23"
                     /locus_tag="VW749_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0175295.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4581..5555)
                     /locus_tag="VW749_001260"
     CDS             complement(4581..5555)
                     /locus_tag="VW749_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0175296.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5563..6819)
                     /locus_tag="VW749_001261"
     CDS             complement(5563..6819)
                     /locus_tag="VW749_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0175297.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6881..7312)
                     /locus_tag="VW749_001262"
     CDS             complement(6881..7312)
                     /locus_tag="VW749_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175298.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7314..7916)
                     /locus_tag="VW749_001263"
     CDS             complement(7314..7916)
                     /locus_tag="VW749_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0175299.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7900..8739)
                     /gene="prmC"
                     /locus_tag="VW749_001264"
     CDS             complement(7900..8739)
                     /gene="prmC"
                     /locus_tag="VW749_001264"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0175300.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(8739..9818)
                     /gene="prfA"
                     /locus_tag="VW749_001265"
     CDS             complement(8739..9818)
                     /gene="prfA"
                     /locus_tag="VW749_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0175301.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLKELNK"
     gene            complement(9828..10307)
                     /locus_tag="VW749_001266"
     CDS             complement(9828..10307)
                     /locus_tag="VW749_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175302.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFCFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10297..10896)
                     /locus_tag="VW749_001267"
     CDS             complement(10297..10896)
                     /locus_tag="VW749_001267"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0175303.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPIMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            11020..11202
                     /locus_tag="VW749_001268"
     CDS             11020..11202
                     /locus_tag="VW749_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0175304.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11339..12712
                     /gene="mnmE"
                     /locus_tag="VW749_001269"
     CDS             11339..12712
                     /gene="mnmE"
                     /locus_tag="VW749_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0175305.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12759..13694)
                     /gene="dapA"
                     /locus_tag="VW749_001270"
     CDS             complement(12759..13694)
                     /gene="dapA"
                     /locus_tag="VW749_001270"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0175306.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13750..14826)
                     /locus_tag="VW749_001271"
     CDS             complement(13750..14826)
                     /locus_tag="VW749_001271"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0175307.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15168..15240)
                     /locus_tag="VW749_001272"
     tRNA            complement(15168..15240)
                     /locus_tag="VW749_001272"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15205..15207),aa:Thr,seq:ggt)
     gene            complement(15340..15849)
                     /locus_tag="VW749_001273"
     CDS             complement(15340..15849)
                     /locus_tag="VW749_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0175308.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIQKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15847..15943)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15972..16403
                     /locus_tag="VW749_001274"
     CDS             15972..16403
                     /locus_tag="VW749_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0175309.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16485..16862
                     /gene="mscL"
                     /locus_tag="VW749_001275"
     CDS             16485..16862
                     /gene="mscL"
                     /locus_tag="VW749_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0175310.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16904..17998)
                     /gene="hemH"
                     /locus_tag="VW749_001276"
     CDS             complement(16904..17998)
                     /gene="hemH"
                     /locus_tag="VW749_001276"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0175311.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(18076..18951)
                     /gene="srtG2"
                     /locus_tag="VW749_001277"
     CDS             complement(18076..18951)
                     /gene="srtG2"
                     /locus_tag="VW749_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HEV0175312.1"
                     /translation="MTVQKRARFKNVFLVFFCVFVALFSWQRVVEASDYDHYNPIEKD
                     ASSTGFETLQHLNKDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTIMGSIFLD
                     YRFNPNFTDFNTIIYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFG
                     ILEVDAYDTEIYRTLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNIT
                     NGRHILLAKITDAPVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLI
                     ILIIRRDKKTKEQKK"
     gene            complement(19029..20027)
                     /gene="srtG1"
                     /locus_tag="VW749_001278"
     CDS             complement(19029..20027)
                     /gene="srtG1"
                     /locus_tag="VW749_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HEV0175313.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(20045..21240)
                     /gene="pitB"
                     /locus_tag="VW749_001279"
                     /pseudo
     CDS             complement(20045..21240)
                     /gene="pitB"
                     /locus_tag="VW749_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
     gene            complement(21285..21836)
                     /gene="sipA"
                     /locus_tag="VW749_001280"
     CDS             complement(21285..21836)
                     /gene="sipA"
                     /locus_tag="VW749_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HEV0175314.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21836..23596)
                     /locus_tag="VW749_001281"
     CDS             complement(21836..23596)
                     /locus_tag="VW749_001281"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175315.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYIGSNDSI
                     TSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQL
                     LPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYVL
                     KFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDYS
                     EKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTSP
                     VQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLTV
                     KKILEGEQSPNKSFTINVTLSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYLP
                     RDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVIKKVTGAFANLL
                     QSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLNA
                     RYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVVL
                     PLGGIFFIILLGHLVVNRRK"
     gene            complement(23918..24421)
                     /locus_tag="VW749_001282"
     CDS             complement(23918..24421)
                     /locus_tag="VW749_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HEV0175316.1"
                     /translation="MNVQYDFKKIQYFTSILVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
BASE COUNT         7033 a         5115 c         4522 g         7804 t
ORIGIN      
        1 atttttcatt aactcatcaa taaaaatttg tttgctaata tctctttctt ctgattttgt
       61 ttcaaggatt attgctacat cattcatatt tttaggtaaa taccaaccat ctggcttatc
      121 tgaatatccc ttgaagccta attgattaaa agtagttatt tgaccagtac cttgattgat
      181 gttttcttca acttcattaa agcctatact tctcttgcat aatccctaac ttgatcttct
      241 gtccttaaag tcattttcta ttcctcgtca ctaaaattat cttcaaaact aataatatca
      301 ttaggagtgc aagataaagc cttacatatt ctttctaaat tcttaaatgt aattggttta
      361 tcctttccca tttgtgccat aacatttgtt gtaagtcctg ccatagctat tacatctgtt
      421 ttctttagtc ctttttttgc taactgtatc cataatggtt tatagttaag tgccataata
      481 tccctctttt tttcttcatt agatttattt aattatagca taaatattga tttcattcaa
      541 tcttacattg atttagtgat ttgttttaga gaatttgttg tgttattccg tccttatttt
      601 gccataaatt gttttaagtg ggacctctta tccttaccat ttttacctcc taattttgag
      661 tataaaaaag acgatagagt ttttaatttc tatcgtctga gatttacata ttaaattttc
      721 atcacaaaat aagactcttt aaagaatctt taaattcatt ggtatgctgc ttacaatatc
      781 cattattaaa atggatattg taagcagcat accaactatt tattttttga gttttaaact
      841 ttggtagaag tcttgaactc cttatattta cataactatt tgcctctata actgttatga
      901 cacgaaacca acaagcaagt tcaagcacct ccatatcttt attcaaatga ggactaagat
      961 attcacaaac tttatcataa acctctttat cttttttcat aaaaggggca tacaacttag
     1021 caaatttatc ctaaaatttt ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat
     1081 aaaaatgatc ctatcaatct ttatattgag cctattttct aattgatacc ttgcaagaaa
     1141 ggaataatag ctgttcctat accaagtagg aatgtaataa atgcagaaag tcatatactg
     1201 tcattctttt ctattaaatc attttgaagt gtctcaaagc atccatgatg gcttcttctt
     1261 tttcaggtgt acactgtgga ataatttgtt tatccttttt agacttgttg taatgttctc
     1321 gtaattctat tccacatttc ttttttatct gtgcaatata taatgtcgaa acttttaatt
     1381 caaatttatt ccaaacatat tctttgattt gagcatatgt tgctttgctc tccgcacttg
     1441 tcaaatccat ctcatccagc tcaatttcaa cacttatgtg cttatcgaca tcaagtttgg
     1501 acaaaagtgc taccgtctcg acgtgatgcg tttgaggaaa tagatccacc ggctggactt
     1561 tcttcaattc atatcccaat tcttggtaga gtttgatatc acgcgccatg gttgcgacat
     1621 tgcaggagat ataggcgatg cgatcggctc ctgtttgggc gcttgctttg ataaagcttt
     1681 ctgtcaagcc cttgcgtgga ggatcaacca agataacggt tggttgaatc ccatctttaa
     1741 gccaattctt catagcattt tcagctgtgt cacagacata gtgggcgttt gaaatattgt
     1801 tcagctgagc atttttttta ctattctcaa ccgcttctgg aatcagttca acaccgtaga
     1861 cttctttgac atgcttggcg actgataaac caatggttcc aataccagaa taagcatcaa
     1921 taaccacgtc atcttttttt aactctgcaa agtcaatggc tgtttgatag agtttctccg
     1981 ccatttcagt attgacttgg taaaaggctg ggccagcgat ttggaagtca tttcccaaca
     2041 tctggtccgt aatatagtct tgaccataaa gagtgcgcca ctccttacca aaaatcgcat
     2101 tggtattctg gtcgttgata ttttgcatga cagacacaat ctctgggaac tgcttgataa
     2161 cttgttcaat caattggtca acacgaaaaa cttttggacg agttgtcacc aaaacgacca
     2221 tgatttgtcc tgaatagtga ccacgacgca ccacaagatt ccgaatcaat ccagactgtt
     2281 ccttttcgtc ataaggtttt aaatcaaaac gacggagcag gtctcgaaga gctactacga
     2341 cttggtcaat gacaggatcc tggataaaga aatcttcaag gggcatgagg ttatgcgaat
     2401 tcttacggaa aaatcctgtt tccaagacac cattcactcg acgaacgggc acctgcgcct
     2461 tattgcgata cttgactgga tgttccatac caagcgtttc agcaacttct acatctgcaa
     2521 ttccagcaat cttgtagaga ctgtccttga cttgcttggt tttaaacttg agctgttctg
     2581 gataagaaag gtgtcctaaa tccgcgattc ctgaacgcag gtaagccaaa tctagatctt
     2641 gattacggtg tggtgactgg acaaggtatt tttcaacttt tccaaagcca atctttttat
     2701 tgaccttgag gacacgcatg aaaatttttt cactcggtaa agcattctct acaaaaaaga
     2761 ccaaaccatc taccttggca actcctgccc cttcatgggt caaatcaaca atttcaactt
     2821 ctacaatatc atttttcttt aacattcttt tctctttcta ttggccgaca aaaaagacgg
     2881 caacgttacg gttaccatcc attataccat gaaatttctt aagaaccaaa actcttgaag
     2941 aagttgacaa gggcttgcca gagggagctt aagaagttac caccgtcctc tagcgcctta
     3001 tccgcatcaa agttaaggtt gatattttta aaactgtcgc cagcttgtga tacgatgctt
     3061 tgtttaaggt catttagggt tttagtgaaa tctgcattgc tgaggatatc actctttgag
     3121 agattcaagg caaaattgat gatgatattg atctggtttc ctgttatgac ctgatcaagt
     3181 ttgtaatttt ttaaggtatc ttcaacaatc ttgcggatat cttcttctgt cagatttccc
     3241 ttgctttctt tagctttggc gagtcctgac ttgatatcag ctagggcaac gtttaattta
     3301 ttagcatcat agcctgattt gtccttgttt tcagcattga tatctgacaa agcctttagc
     3361 tcttcttgag ccaaatcttt attggcttgc ggcaccttgg ctccattagc ttctagcgaa
     3421 tagtagatcc cagccaaagc actctcacct gtaactggaa tgggtgctgc tacagtgatt
     3481 ttggcgtgtt ccacacccaa agttacggct gcatttcggt acatatcctg agttacctta
     3541 gtgatgtttt caggtgtttc aatcttgacc tcaagtggcg atttgtcacc tagcttttga
     3601 atcttggctg atgaatacaa ctgtaagcta gagtcattgg ccacattcat gattttagaa
     3661 taaacatcag gtgtcatggt cttgagttct ttggtatctg ttgaggcatt gtagcccagt
     3721 tttttaagag tttgattttt ttggtcttca gatagggaag aacctaggac atattcaggt
     3781 tggacatagg tttcatcgat aactttttga acatctgttg ctgcatggac gctattcata
     3841 gctgttactg cccacaagat cgcagcgcta gtcagaaaga gtttctttct catagggaat
     3901 ttcctccttt acttctttag agtaatatat ctatcttaaa gaaaacttat aacaaaaaca
     3961 cctggtctag ccagatgttg aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg
     4021 tacctgtcta gaataataat agtttcctcc atttacatag agttcagcac cgtgaaaaat
     4081 ggaaatgggg tgaatataac tataagtctt tccagtcgta ttaccaagca agggggcaac
     4141 agtctcacga gagtactgtt tggctagagc caaggtattt tccttgccat tttgggcgat
     4201 aaaatcgata taggcaggtc caaaattata ggcttgaaca gctgtccaga tatctacacc
     4261 cttcttctgc gccagataga gattgcctgt cagagtttga atgccttgcc gaatgctaga
     4321 ggcattatca ttgatggtgt tggtggaacc acttgcagac tcactagact gcataacatc
     4381 gccttctttt ccttttgttt cagtataaat catagcaagc acaagctctt cgtttgctgg
     4441 ggtgtctttt tcactcaata tttctcgcac catgggttga taggtcatga cttgtttgac
     4501 atcttgatga acgcggtaag ctttatagcc agcaaaaagg aagactgcta gtacaagcac
     4561 tcttcgaatt cgtttaaaca ttatttactt tggatatcct cgatattttt gattaagata
     4621 gagtaggttc cattttcgtt ttggataaac tcaacagact cggcgtcttg atagacgtta
     4681 ttgggaacga tgagctcaat tccatttgat aaggagagtt tttggttttc aaatttcttt
     4741 aattggcgac tggcatcaat ttcatcaaat tgaacaggtt ctggtacggc ttctttgact
     4801 tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc
     4861 tcaggtgaca attcattgct ttcttctagg ttgttgaaaa tagctgattt gaccttggat
     4921 tgaaattgaa aatcatctgt gttaaaagat tcagcaattc tctgggctgt tttttccagt
     4981 tccttgatag attttttagg agaaatctta ggagcgacag caagaagatt atctgaaaaa
     5041 tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa tcaggtgata cttgcgactc
     5101 tgaagattga ccaccaaggc ctcgtcagca cccgttccaa atccaggcag gttattctga
     5161 gtcagcttga ttggattatc aacttctcct ccgaggtggg tcaaggtctc ccgcagggca
     5221 attcgcaaga aagcgaaatg ttctacacct tctttagaaa attgaacaaa aatcaagtca
     5281 ttggtcttga gattttcaga aatgctaaac tcctctttcc agagattagc cagcgttact
     5341 gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc
     5401 ccagtcttgg cttcatctga atacacatgt tcaatttttt tacgtaggta ttcttcgatt
     5461 tttggagtaa tattgagaaa cttatctgct aagaacagct cggtatcatc cggactgaac
     5521 tggtgaataa tggctttctt aatataaatg tccataaaag ttttattcct cgtataatgg
     5581 gaaggcatct gtcaattctt tgactgcact tctcacttct tctaatacag cctcattttc
     5641 tgaattctta agggttttaa tgatgagttc agccactttg cgactttctt cttcaccaaa
     5701 tccacgtgca gtaatggctg ctgctccgat acgaatccca cttgtcttga atggtgacaa
     5761 gctttcgtaa gggattgagt ttttatttaa ggtaatattg acttcatcca acaagttttg
     5821 agcaactttg ccgttttcta caactttagt cacatcaaca aggaagagat ggttttcagt
     5881 tccacctgaa ataatacgga aatcagggtc ttgcaagaag acatctgcca tagccttgct
     5941 gttcttaatt acattggcag catattcctt gaaggctgga tccaaaactt ctttgaagga
     6001 aactgcctta gccgccacaa catgctctaa aggaccgccc tgaatacctg ggaaaatagc
     6061 tgaattgatt tttttagcaa gttcttcgtc attggtcaaa atcaaaccac cacgaggacc
     6121 acgaagggtt ttgtgggtcg ttgttgttgt gatatgagcg tatggaactg ggcttggatg
     6181 aaggccagcc gcaaccaaac cagcgatatg ggccatgtcc accatgagct tcgcaccgac
     6241 agcatctgcg atttcacgga attttgaaaa atcgataatt tgagaatatg ctgaagcacc
     6301 agctacaatc agttttggtt ttacttcttg ggcttgtttc aagatagcat caaagtctaa
     6361 gagttccgtt tcaggatcaa cactataaga aacaaagttg taggtttgac cagagaagct
     6421 aacaggagcc ccatgagtca aatgaccacc tgatgccaaa tccattccca taaccgtatc
     6481 acctggctca atcaaggaca tgtaagccgc acagttagct tggcttcctg aatgtggttg
     6541 gacattggca aatttagcac cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac
     6601 aacgtctact acatcagttc caccataata acggcgtcct gggtaaccct cggcatattt
     6661 atttgtcaag atagaccctt gagctgccat aacagccttg gaaactacgt tttccgaagc
     6721 aattaactcg atattatttt gttggcgttc ttcttctttg gcaatagcat tccagagatc
     6781 agcatcatat gctttaaaat catctttgtc aaaaatcata ggtcttctcc tttattgtgt
     6841 gactagtcca ttagtttgat tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc
     6901 gtttctgcat tttatcacaa gtatagccaa ctttttcata aaatgcatga gcacccagac
     6961 gatgattggc agaatttaag cggataaacc cataaccaca tcttttggct tcttgttcca
     7021 acccttgtag taaactttta ccgatacctt caccttgcgc ttgaggtgaa actgctaaag
     7081 ctaagatatt aaatcctgct ttggaataga gtgattcgta aacttcagcg tggacatatc
     7141 caagtaagac atgattagct gcatcctcat agccaagtag gaaatgatgg gaatcctgag
     7201 acagtctagc tagttggcta gccgtttcct ctagactaaa agtataaccc aaagcctctt
     7261 ggttgatgtc acatatcgct ttcacatctg tttcttgcaa atctcttagc atttcaagcc
     7321 tcctcaaaag aaatctctgg caaccgagca agaatatctt ctcgtttaat tgcgccttgg
     7381 cgtaagattt tcaccttgtc tccagacaaa tccacaatag ttgaatcctg tccagttaga
     7441 aaagcatcgt cttccagacc cagaacctct tggtcaaaat ccttcagaat ttgttcaaag
     7501 gttacaccac ttgcctgacc tgagatattg gcagacggcc caatcaaggg acctgtctct
     7561 cgaattaaat ccagtgtgat agggtgactg ggcatccgaa atccaatagt tgcaaggtca
     7621 gaatttaccc aatagggaac tcggtcattg gcttcgagaa taatggtcaa gggacctggc
     7681 aaaaaggtct ctacaagttt ttgtagataa gttggctgat tcttagaaaa gtgcaagata
     7741 tcctcgaaag aggcgatatt gagattgagt gccttatctc taggacgacg tttgagttgg
     7801 taaacatggt caactgcttt ttcatctaag gccttggcaa aaagaccata aacagtctct
     7861 gtaggtagaa cgacagctcc accattttcc aactcttgtc taatcctgtc tatcatcaac
     7921 cacgaccatc ctattttgac caaattggtc cttgagtgtt cgaactcttt tttcaggaag
     7981 atgtttccta aaaagttcgg gaacactttg accttgcttg tatccaattt caaggtaaat
     8041 cttaccacca tctttgagat agtcttttgc atcttccgca attctacagt aaatagctag
     8101 gccatcctcg tctgcaaaga gagctagatg aggctccgaa tgcaaaacat tcaagcctac
     8161 ctctgactca tcttcacgag agatataggg tggattggat acaattatat catatttttc
     8221 agaaatttct gcaaaacaat cagatttttt aaaaaatata ttaagatttt gattgctagc
     8281 attctctgat gcaagctcta aggcctcttg agaaacatct gctgctgtca ctgaccaatc
     8341 tggtctattt tttgctagag cgagagcaat agctccacta cctgttccaa tatccagaac
     8401 tgaaagattc gtctcaagat tttcagttag aataagctcc actaactcct ctgtttctgg
     8461 acgaggaatc aaaacccgtt catccacctt taaatgcatt ccataaaaat ctgcctgtcc
     8521 aatgatgtac tgagctggct tgtgagctgc tagttgctgg taaatatctt ctacaaattg
     8581 tttttcttcc tctgttgtca cctcctgctg gagggcaaaa ataaagtctg taaaagatag
     8641 atttttcaga ctacgataga caaaagagag gctttccgct tcctctcctt gtcttatcaa
     8701 ctcttcttca aaatttgaaa ataattgagc taatttcatt atttgtttaa ttcttttagt
     8761 ttttgtgttt ggtcataaag caccaaggca tccacaactt cgtccaattt accagacaaa
     8821 atcgtatcta gtttttggag ggtcaagccg atacggtggt ctgtgacacg gttttgtggg
     8881 aagttataag ttcggatccg ttctgaacgg tcaccagtac cgattgtcga cttacgctca
     8941 gcgtcttgtt catcctgagc aatctgagca aagtggtcag cgacgcgtgc acggataatc
     9001 ttcatagcct tctcgcggtt cttctgctgg gtacgttctt cctgcatctc aaccttgata
     9061 ttggttggca agtgaacgat acgaacggca gtcgcaacct tattgacgtt ctgtccacca
     9121 gcaccagagg cgtgatagat gtcgacacga aggtcttttg gatcaatgtc gtattcaacc
     9181 tcttcaactt ctggcataac aagaactgtc gctgtcgaag tatgaacacg gccttggctt
     9241 tctgtcacag gaacacgttg cacacggtgg gcacctgatt catacttaag cttagagtat
     9301 acagactgac ctgaaaccat agcaaccact tctttaaaac caccgacacc attcatagag
     9361 gcttccatga cttcaaagcg ccaaccttgg gcttccgcat acttttggta catagttagc
     9421 aaatctccag cgaaaagtgc cgcttcgtct ccaccagctg ctccacggat ttcaaggatg
     9481 atattcttgt catcgtttgg atcctttgga aggagcaaaa ttttcagttt ttcttcatat
     9541 tcttcttttt cagccttggc atctttgagt tcttgcttgg ccatttcttc caagtccgca
     9601 tctccgcctg attccttaat catctcttcg gcatcgacga tattttgaag gacttgttta
     9661 tactcacggt aggctattac ggtgtcacga ttggaagctt cttcttttga aagctccata
     9721 aaacgcttgg tgtctgaaac gacatcaggg tcactcagca attctcctag ttcttcataa
     9781 cggtcttcta cagcttgtag ttgatcatag atgttcattt tttctcctta tttctcaatt
     9841 gttaaatcat agattgctac tacttcattc tcggatattt ccccagtttc tttaaatcca
     9901 taactgagat aacaaaatct tgcctgttca ttttctggtt cataagacaa ccaaagttta
     9961 ttgcttaaac ctgctggcgc tgttcgaaca tagtctagta ctttatccat aattggttta
    10021 aaatatcctt gattttgaaa attcttatca atcataaaac aaaatagtaa ataatttcca
    10081 ctactaatta cgatcttttt atcataagct atcatcacaa aacctataat tacatcatta
    10141 tcataaactg ccaatggagc tacaaaatct ccatttttag tgtagacgta tgcttcagct
    10201 aaactaattg cgttggttgc aatgaattgt ttttgatatt ccttgacatc caaatttaaa
    10261 acatcaaaat aattttccat tgtaacatct cttagttcaa ttgtcatagt tttgctcctt
    10321 gttagaggtt atcattggcg caaaataatg tttacggcaa accgagatat aggtttcatt
    10381 accaccaatc tggatctgtt ctccatcgta aacgggcagt ccatcctgtg ttcgcaacac
    10441 catggtcgcc tttttcttgc aatactgaca gatggtcttg atttcgtcaa tcttgtctgc
    10501 taaaagcaag agatatttgg aaccttcgaa caattcattg cgaaagtcat ttttcaaacc
    10561 aaaagccatg atgggtatgt ctaactcgtc cacaacacga gctaggtcgt aaacatggtg
    10621 gcgtttaaga aactgggctt catcgaccaa aacacagtaa ggtttttctg gtaggtctcg
    10681 gatatagcca aagatatccg ttgtttcctc aatcgcaagg gcagggcgtt tcatgccaat
    10741 tcgactcgac acatagccaa caccgtcacg cgtatccaga gccgaggtca taatgacaac
    10801 accttttcct tgctcctcat agttataggc caccttgaga atctcgattg tctttccaga
    10861 gttcatggtc ccataacgat aatacaactg tgccatgttt cttgcttcac gtccatttct
    10921 aaatttttgc tacattctag tatatcataa ttttcttaag ctttaaacgg caaaatgtgg
    10981 taaaatagaa gaaatcaaaa actagtggag gaagctatta tgccatttgt acgcatcgat
    11041 ttatttgaag gacgcacgct cgagcaaaag aaagctcttg ctaaggaagt aacggaagcg
    11101 gttgttcgca acactggagc acctcaatct gctgtccatg tcatcatcaa cgacatgcca
    11161 gaaggaactt acttcccaca aggggaaatg cgtaccaaat aagctagctt aagcagaatt
    11221 gcttaggctt tttcaatctc caagtagcat tcattgaaga aatatcctaa atttgttaca
    11281 atttgaaaag aaacttggag aatttccaag aaaatagcta ttaattaaag gaaacattat
    11341 gattacacgt gaatttgata ccatcgctgc tatctctact ccactaggtg aaggggctat
    11401 tggtattgtc cgcctgagcg gaacagacag ttttgctatt gcgcaaaaga tttttaaagg
    11461 aaaagacttg aacaaggttg ccagccacac tctcaactac ggtcacatta ttgatcctct
    11521 gactggtaaa gtcatggacg aggttatggt tggggctatg aagtctccaa agaccttcac
    11581 tcgtgaggat attatcgaga ttaacaccca cggtggtatt gcggtgacca atgagattct
    11641 ccagctagct atccgtgaag gagctcggtt ggcagaacct ggtgaattta ccaaacgtgc
    11701 ctttttaaac ggtcgcgtag atttgacaca ggccgaggcg gtgatggata tcatccgcgc
    11761 caagacagac aaggccatga acatcgcggt caaacaactt gatggttccc tttctgatct
    11821 tatcaataat atccgtcaag aaatccttaa cacacttgcc caagttgagg tcaatatcga
    11881 ctatcctgag tatgacgatg ttgaggaagc cactactgct gttgtccgag agaagacaat
    11941 ggagtttgag caattactaa ccaagctcct taggacagca cgtcgtggta aaattcttcg
    12001 tgaaggaatt tcaacggcta tcattggacg tcccaacgtt gggaaatcaa gccttctcaa
    12061 caacctcttg cgtgaggaca aggctatcgt aaccgatatc gctgggacaa cacgagatgt
    12121 catcgaagag tacgtcaaca tcaatggtgt acctctcaaa ttgattgata cagctggtat
    12181 tcgtgaaacg gatgatatag tggaacaaat cggtgttgag cgttcgaaaa aagccctcaa
    12241 ggaagccaac ttggttctac tagtgctaaa tgccagtgaa ccactgactg cgcaagacag
    12301 acaacttctt gaaattagcc aagataccaa tcgcattatt ctacttaata aaaccgacct
    12361 gccagaaacg attgaaactt cgaaactacc tgaagacgtt atccgtattt cagtccttaa
    12421 aaaccaaaac atcgacaaga ttgaagagcg aatcaacaac ctcttctttg aaaatgctgg
    12481 cttgattgag caagatgcta cttacttgtc aaacgcccgt cacatttccc tgattgaaaa
    12541 agcagttgaa agcctacaag ccgttaatca aggtcttgag ctggggatgc cagttgattt
    12601 gcttcaagtt gacttgactc gtacttggga aatcctcgga gaaatcactg gggatgctgc
    12661 tccagatgaa ctcatcaccc aactctttag ccaattctgt ttaggaaaat aagaaaaatc
    12721 catgatcctt cattcggtca tggattttat tgtctttatt agtaatctgg tcttaagacc
    12781 cctgttacag ttgccttagt tgcttcgtag tcgccatcta cgacaacctt gataatgcgt
    12841 ttggcatctt cttctggtgc tggaacaaga ggtagacgag tgggtccagc ttcaaatccc
    12901 atatagttaa gaattgcctt aactggagca ggacttggat aagagaagag agcattaacc
    12961 ttaggaatga atttacgctg aattgctgcg gctttcttca tatcgctttc tgcaatggca
    13021 gtaaacatct cgtgcatttc atccccattt gtatgagagg caacagaaat aaccccatcc
    13081 gccccaaggt tcatggcatg gaaagcatct ccatcctcac ctgtataaat caagaactct
    13141 tcaggcttgt gctcaatcaa gtaagccata ttagccaagc tagtacattc tttgacaccg
    13201 ataatatttg gatggtcagc caagcgaagc atggtttctg gagtcaattc gacaactaca
    13261 cgccctggaa tgttatagat aataattggt aggtcagaag catctgcaat agtcttaaag
    13321 tgctgataca tcccttcttg agaaggtttg ttgtagtaag gaacaatagc aagcccagct
    13381 gcgaaaccac caaattccgc tacttctttg acaaactcaa tagagtcacg cgtatcatta
    13441 gtacctacac ccgcaatcaa aggaacgcgt ccattgacaa ccttttgtac agccgcaaac
    13501 aactccaact cctcatcgtg ggtcaaagtt ggactctcag cagtcgttcc tgcgagaaga
    13561 attccatccg tatgatgggc caataaatgc tcaatcaagg ctggaatagc atcaaagtta
    13621 atagaaccat cctcatgaaa gggggtaata aaggctgtaa tgattttaca ttcttttaaa
    13681 tcttgataag acatgaaaac acctctctat ttcaaagaag gagttcatct gaactcctaa
    13741 acgatatgac tattttaatt caaatttcaa ttcggctgtt ggacgaacca atccacgttc
    13801 atgaagagtt tcagcaatct gaactgagtt ccaagcagca cctttgagaa ggttatctga
    13861 aacaacccac atgtgaattc ctttttctgc atccaagtct ttacggatac gaccaacaaa
    13921 ggtatcacgc gaaccaactg cattgatagc ttgaggatag atttgatgag ctacatcatc
    13981 ttcaagaaca gcacctggga aggctgcgat agctgctttt acttcttcga ttggagccac
    14041 ttcttttgtt tcgatataaa cagactcaga gtgagctgac aagactggaa tacgcacaca
    14101 tgttgcagat actgcaatgc tatcatcttc cataattttc ttagtttcct tggtcatctt
    14161 catctcttcg tacgtgtaat cattatcagt gaaaacatca atttgtggaa gagcgttaaa
    14221 ggcgatagga taatgtttct tgtcaccacc tgaaggcaaa atttccgcat gcaaatcaca
    14281 tggtttcaca ccatcattca agacttcacg aagttcacgt tgtgtctcaa gaattgctcc
    14341 cataccagca cctgaaacgg cttgataagt tgaaacaatg atacggtcca agccccattt
    14401 ttggcgaacc ggctcaagag ccaccatcat ttggattgtt gaacaattag ggcaggcaat
    14461 gattccgttg tgggcatcaa gtgcatgagc attgacctct ggaacaacca aaggaacatc
    14521 tggattttga cggaaataag atgtattatc cactactacc acgccagctt ttactgcgta
    14581 tggtgcatac ttagctgatg tagaactacc tgctgaaaag agagcaatat caactccttc
    14641 aaaagctgtt tcagtcgttt cttcaattgt aatatcttga tctttaaatt tcaatgactt
    14701 acctgctgaa cgtgcagaag caaggtaacg gattttatcg attggaagtg ttgattcttc
    14761 caacattttt atcatctgag caccgacagc acctgtcgcg ccgactacag caactgtata
    14821 tcccataaat aacctctttc ggaattttct aaaaatttct ataatagaag tattatacta
    14881 ctttttccat gaattgcaaa gctttttcat cattttttgg aaaataaaaa tcccagtcgc
    14941 tagactaggg actaagaggc atcttcatgt gatgagcagg ttcacacaac tcatcaaggt
    15001 ccgctcctgc gttatgacct ccttatgctc aatagtagtc cgaagactac ctatcgactc
    15061 atcgcatatt ctatattact agagatactt gattttgtca ataagaaatt ttttcgatcg
    15121 agtataacaa aaaactctcg tattcaagag tttccctata catatcatgc taattgccgg
    15181 gatcgaaccg gcgacctcat ccttaccatg gatgcgctct gccaactgag ctaaatcagc
    15241 ttacttaaga agtatactat attcagaaaa acttgtcaag tttccttaga aattttccat
    15301 aggaaaaagc caggtaagaa ctacctagct tatcttcttc tatttactta aatcaattcg
    15361 acgaccaatt ttaccaataa taatcgcccc aataatcaat gaagcaaatt caccgattcc
    15421 tgttgtaaac caagtaagga agaatggtaa ttctgctaca atatttaact ctgcagcgat
    15481 agtaaacatg gaaattgaaa agaggattga aaagaagaaa tgatcttttt gaatcaatcc
    15541 gttaaagagg taatccttgc tatattttgc aaaaagccaa acacctaaac tgaggaatac
    15601 taaggttgaa ccaccaccaa caaagacatc tagcagtccg aagctaaaga aattagcaat
    15661 catacaaccg atggtaactc cgatgatgta cttaggattg taaaaagcca taaagttcat
    15721 catttctgaa atacgaaact gataagcacc atagctgatg gcatttaggg gcggtgtgac
    15781 agtcaaaacg acgtagatag cagcgacgat tgcaatatct gcaacatcac gaatagttaa
    15841 ttttttcatc ttttctcctt tggcggttgc ccgcgtgtaa tatgcttggt gaaagaagct
    15901 aagcaccaag ggttgcttta ttcaacccta ctagtatagc acaatagcct gctttatgct
    15961 atacttaaca catgaaaatt cctattcaaa aattttttaa caatgaaatc ttagcctatc
    16021 tcttttttgg ccttgcgaca actctagttt cgattctctc acgactagtc atttatcaac
    16081 taagtcatca ggaactcctg gctactgccc tagcaaatat tatcggtatc ctatttgcct
    16141 ttatcacaaa tgatacgatt gtatttaagc aaaaaaagaa aaatagactt atccgtttag
    16201 tgaaattttc tcttgctcgc ctttctactt ttctgttaga cttgttttta acttttctct
    16261 ttgtaaccca atttcctcac attatagggc aattcgtaac tgaaaacatt gataagataa
    16321 atgctattga aacaataatt gcacaaatat tcattattat catcaattat atattgagca
    16381 aggcctatat ttttagaaaa taatgctcca tttatgagcc ttttaattgc cttctataat
    16441 gatttaggat acaatgaaac acgaaacatt gaaaggaaaa cagtatgtta aaaaatctaa
    16501 aatcgttctt gcttcgagga aatgttattg accttgctgt cggtgttgta attgcctctg
    16561 cttttggtgc tatcgttact tcacttgtaa acgacattat cactcctctt attttaaatc
    16621 ccgctttgaa agctgctaaa gttgaacgta tcgctcaact ttcttggcat ggagtcggct
    16681 atggtaactt cttaagtgct attatcaatt ttatctttgt gggtaccgcc ctcttcttta
    16741 ttatcaaggg cattgaaaaa gcacagaaac tgactggcat aaagaaagaa aaaactgccg
    16801 aaaaaaaacc aaccgaattg gaagtccttc aagaaataaa agctctcctt gagaaaaaat
    16861 aatcgattaa aaggatctag cgcaaagcta aatccttttt tctttactct ttgggtaact
    16921 tgcctgcttt ttcaagcatt tttttgatca gataaggcat cttaacattc tcccgccctt
    16981 ttttctcaat cagttttttc acaaattctg gcatttgtaa atcttcagat tcagctaaaa
    17041 tgtttttcgt ctcgtctgaa ggaactaact catcaaaggt ctcttcttct gggagaaatt
    17101 ccttaaactc ttgattttca ttgactctaa ctgtattgac caaagcatca atcaaacgag
    17161 aatctgtatt tggcattggt ggacgatggt agtttacccc aaattcctgg cataagtcat
    17221 aacattctac atcattgtca aacaagacct caatatgctc actgatgaaa ctaataggta
    17281 caaaaatata atggtctgga tgttctgtct gttctctgag atactccaaa acatctggtt
    17341 taatccatgg aataccaata tcactctcac tctgccaagt gttggtatat tgttctgaac
    17401 tcaagcccag tttttcagcg actagcttgc tattttcgaa aatttggtct atataaggat
    17461 caccaaagtc caaggcaaaa atgggcacac tatgggctga aaagatgact ttaaagctgt
    17521 cttgctttac ttcttctttt aaaatcttag caatttcatc tgcccaatag tttaagagca
    17581 cttcttcctg ataccagtcc ttaatgacca aaaattgaat ttgtttgctt tctaaaaatt
    17641 tttcatagcc catgacagag tagaaagaat aatggggctc caaaatcaag cagatacatt
    17701 cttcaacacc atcagtttcc atctgcttga tcacgtctgg aataaaggga cgagaaaatt
    17761 tgttggcaaa gtagataccg tactcctccc ctaaacgttc tttgactaaa ttgacctcct
    17821 cacgtgtaat ccgctgcaaa ggcgtcccac cgatacgaat atagttgtca tagagagtct
    17881 ggatttcgtg gtcttggggt ctaactccac gacgaatgtt tgtaaagaat tctgctactc
    17941 cttcaaaact aatctcctct ggagatccaa aggtcatcat taatatggct tttttcatgt
    18001 tatcatcctt atgatattat tttctctatc cattctatca tgaaagaaaa aaatagtaaa
    18061 cgtttcctac gtctactatt tcttttgctc ttttgttttt ttatctcgtc ttataattag
    18121 gatgataagg acaagaagta agaggacgat aataaggagt agaaaggcta gaatgtaaat
    18181 ccaatgactg ggaattccgt gatcgaaata ccgtgttcct actgcttccc cactttcatc
    18241 ctgtgctact ttcaccggtg catccgttat tttagctaaa aggatatgtc gtccattagt
    18301 tatgttaagg aaacaggtgc ttaataaaac aatcttgtcc gttgaggtca aggaaacatc
    18361 tcgcttgtac ttggctttac ttagcagata ttgatagtaa gcctggtgtt cctcatcctt
    18421 ggaactcaag gttcgataaa tctccgtgtc ataggcatcc acttctaaaa tcccaaaaat
    18481 ttcaagacca cgttctcgac cattgtagta gatagaaccg tagcgatgct ggtcgaagaa
    18541 ttccttatca gcaaatttct taatctcacc gaacatagcc cctgaagcca tagagtgtcc
    18601 gtagatgatc gtattaaaat cagtaaagtt gggattaaag cgatagtcga gaaaaattga
    18661 tcccattatc gtataatcgc caaaggcatt gcggtcaagg tatttgacat tatcctgact
    18721 ttgtagaagc ggatagtcta ccttggtccc atcaaggcta atccaaccgc aaacatcttt
    18781 gttcaagtgc tgtagggttt caaaacctgt gctcgaagca tccttttcaa taggattata
    18841 gtgatcatag tcacttgctt ctactactct ctgccaacta aaaagagcta caaaaacaca
    18901 gaagaatacc agaaatacgt ttttaaatcg cgctcttttt tgaaccgtca tcagcactcc
    18961 tttctatgcg agatttctta aaaggaaagg aggcgggaca aaaccgcctc ttttctattc
    19021 acccttagtc agtaaaaggg tctgcttctt gcattttttt tactctctct tctacgacgt
    19081 aggatcaagt agaggacaag gagtaagaaa atcaagagca agaacaatac aaacaagata
    19141 aggtaccaaa tccatagtgg gattgatgag aggaaacgtc caagagacga gtcatcaaag
    19201 acactgtatg gaaatggttt tgattttttt gtatggaaag tatttttagg gacggtgtct
    19261 gtaatctttg cgactacgat atgacgacca ttggtcacat cgagaaaaca ggtactgagt
    19321 aggatgatac gatcactcgg tgagagtgag atatcccgct tgtgcatggc gactgagagc
    19381 aggtggtcta gataggcctg ctggcggtcc tcaccctgta ttcctggatc atagatgtta
    19441 aagtcatagg catcaacctc caacatctca aagatctcga gccctttttc cacaccattg
    19501 tagtatatac taccgtaacg atgctggtca aaaaattcct gatcagcaaa cttagccaca
    19561 tcaccaaaca tgaccccatt ttctacgtgg tgcccgtaga taatggtatt aaagtcttcg
    19621 aacttaggat tatttcgtgc atcgagaaag atagcgcctg tcgctgcaaa ctcacctttg
    19681 gagtccttgt tgagatactt ttcattgtcc ttggcttgga ctaagggata gtcgatattg
    19741 gtgccataga cattgatcca accgaggact tcgggattga gttcttggag tttgctgaag
    19801 cctgaaaaac tggccagctc atcctgttgc gtcgtgacag gtcgataagc ttcgtactca
    19861 cttgacgaag ctaaggagta gacttggttg gaatcccaaa gggcgtagaa accaaagaga
    19921 aagatcaaag ctgcaaaaat gagcagcaag tgattgatca ccccatccac agcaagaacg
    19981 agacgcctag acagactctt ttttggtttc tcacgcttgg ttttcatcat ctgcccccag
    20041 ccgtttaggc ttctctacgt tttttagaca agacaacaaa tccagccaaa ccaagaccaa
    20101 tcatcaaaat gaatggaagg ttatcaatca agagaccagt aggagtaacg tcgtcgattt
    20161 tgttagtaac tttgttgtcg tttttctttt cacctatgag gatatctgtt aatgtaaaat
    20221 ctacattttt tgtccttgag atgtttgttc tgcaccattt gtagtataaa ttgatgaatc
    20281 tgtataacct gctactccag tttcagttac tgtatattta gaacctgctg gtagttgttc
    20341 aactgtaaat gtttcaccat ctttaagagt aaaattgtac tcaactgtat ctgctggggt
    20401 cactactgcc aacacctctg acttagatcc atgttttact ataatattcg taacaggggt
    20461 ttctgctgtt ttatttgtac ttggaagttg aatcttgata tggaattgga aatctcttgt
    20521 tttatcccct gaagctccat caactttttt agtaattgtt aatgctttcg cattggggtc
    20581 tacttgactc ggatcatcag gattaggctc cttacttgcg tctttggtat atgtgttatc
    20641 aaataaatta taaacgcctt gttcacttgg ttctacttta ggggcgttag atttattatt
    20701 ttccttaaag tatactgatg aaatatagac accaccattt actttattct taacaataac
    20761 gtgcatttca tatgtacgtt tgtcgtatct catggcatca attgttttac catttttggt
    20821 aatcgcctgc catccagttt ttgcttccgc tacatcataa acgtattcac cagcatggcc
    20881 ataagcaact cccgaaaaaa tgtcttctgt tgctttttga atcttatcag cagttgggtg
    20941 atcattttta ttgtattcta catttctatc tggaattgca actccggttt gatatggcgc
    21001 accgttagaa gattgtcctg ttttttctgt aaacttaaat gtaaatgtcg ctgttggtgt
    21061 tgttattccc tctgcaatat tcaacgtttt attaatcttc acaacagcat tattttcacc
    21121 atttgctttg gttattgctg aattatcatc cgcaaaagtc gggacacctc tgaatacgga
    21181 caaagcggtt atagctgcaa tgcttgcagt gaatagcttt ttaaagaatg tttttttcat
    21241 gattatttct tttgtttttt tattttcttt tttcattatg atcatcaaaa gcctcgtctt
    21301 ctaatgactg ttacaacttt gccttgagta tcctgtatag ggatggttcc aaaagcacga
    21361 ctgtctacag ccgttgttcg attgtccccg aggacaaaaa gttgtcctgc tgggactttc
    21421 atcgggaagg ttgccccttc cttatagagc agcgtttctt tgtagatatc ttgctcttgt
    21481 tgaggagaac cgttgatgat gagaccattt tcgtttatat cgattgtact tccttcggtt
    21541 gctatgacac gcgccactct ttccttacct ttataactat agactagcaa atcaccaatc
    21601 gaatagcgtt tatccaacct ataatagacg accaagtcgc catcttttaa ggcgggcttc
    21661 atgccatcgt cattgtatct taataatcca aagacgaaaa agtaaaggat ggctagtaca
    21721 aatccaacca tcagaagttt actgactaag taaaggatat ctccccagac actcggcgga
    21781 gacttatccc gattgacttg tgttactggt ttcttatgtt tctttttaag cagcatcact
    21841 tcctcctatt caccacaagg tgaccaagta agatgataaa gaagatccct cctagaggaa
    21901 gaacgactcc aagcacgaga gtgctactca agaagtcaat tcccgtttca ggtacgctgt
    21961 ttttattatt cgtgactgtc gcagacttat ttgcatcaag agttccttct tttttatcat
    22021 aggacacctg atacccacga gacgaacttg cttcttcttc gatactataa cgagcattta
    22081 gaggaaggtc gagaatcttg atggttttat ctttctttag atcaactgtc gccttaccat
    22141 tggtgaattg tagcgttgtt ttttgattat ttactattgc actatacgat ccattcaatg
    22201 gtttattttg cgcatccttt acgttaatgg taatcttaaa ggattgcaga agattagcaa
    22261 aagcacctgt aacttttttt atgactgaaa gtgtcggaag tctgtggttg gtgacgattg
    22321 tttgaacatc ctctgacaaa gtcccctctt gtttttcata ggtgacatga tatcccgttc
    22381 tagagttctc tacttcttcc accttatagt gggtatcacg aggcagataa ctgagggcag
    22441 tttcctgact atttttgaga gaaatctgtg ctttcccgtt agtcactgtt gtattcccaa
    22501 acttgccgtt aatcggcttg ccatccttat ctgaaagggt aacattaatt gtgaaagatt
    22561 tattaggtga ttgttcacct tctaggattt tctttacggt gagacttgga agctgtcggt
    22621 aaataacttt gaaggatggt ttctctttcg tacctgtctt ttgaacttcg actgtgtatc
    22681 ccggagcgtc tggtgctttc agttcgtagt catatccctt agctaccttt gcaaaactag
    22741 tattttcagt aaaactattc gtttgaactg gactagtgac ctttcgatag gaatccttta
    22801 tacttccatc tttcttttgg tttaagttta attcgacact aggtggacga tttgctgatg
    22861 gatttgattt tccatccaca cctttccact caatctctac aggaaccgtc aatggatctg
    22921 acggcttgaa agtgggcttc tcagaatagt cttttatttt ggtacgtgag gtcccaatac
    22981 cataggaata ggcaactttt gcccccttgt tggagtagag tttagtagca tcggcttctt
    23041 cggcatcatc actagtaagt gtcttatcac ccgcaatcgc atcaaatgcc tcttggctag
    23101 aggtgacagt aaacttgaga acgtacttgg cgtcatcctc taaagtgtaa ctcggattaa
    23161 acttggctgt tacttccact aatccctgtt cgttcttctt agtttcaatc gtaacttgat
    23221 tgtcattcag ttcttgctcg ttaccatcct tgattttgac gacacgaagg tgtgaagcat
    23281 caccaggtaa cagctgcacg tacttggaca agacatctga tatagttaca tggtgtacgc
    23341 ctagaggtag aattttatct gtgatttctt tgaatttttg ttgcaagtca ttttcattat
    23401 tggcagaaaa tatttcgttg gggattccag aattataacc actgatatat cctttaagag
    23461 atgtgatact atcgtttgaa cctatatatc tgaatttgat tgaataaaag ccatctattt
    23521 ttggagctat taaactagat atattcagca ttcctctctc taaaccagag gtaaaccaat
    23581 atggagtatc aatcatacgt cccacatttg gattagaata atagttatat attgttctcc
    23641 cactattaga ctcgtaatac atattagctt cgccatctga cagcagaata actacttttt
    23701 ttgccccagc ccttgcactt tgcaacaatc tttgagcttc agttaaccca gcatttatat
    23761 ttgtcccagt gccaatgccc gcgtccatac cataagaacg actagagtca gcaattgtta
    23821 acgaactaac aatatttttt gagctattag aatccgtgct ccaagatact aaagttttag
    23881 catcatcata tgaagagata tttgaatacc aaccagctca atttggccaa gttccatatt
    23941 gataactcag ataatattca ttataataac ggtcattata ctgattatca atctttccgg
    24001 caaaaccaac tatagacaga cggttttggg aattagaaag aattgtatca atgagcccct
    24061 gacgaccatt cacacctttc agtgtatgtt ttagtgcttc aatcctacta atgtatcgtc
    24121 tactagagta agaccacaca tctcgctctt ccatactccc tgaaagatcg gcaaccaaga
    24181 ctacatccaa gggttctgac tgggtctccg ttcccagttt agatgtgata tccagtgaca
    24241 actcatactg gtctttttgc cctgatatcg gagtaatcgt tttgtgcaga gttgtctgag
    24301 gttcagttat tgaatctgca cgtaaagaat taattggtgc acacaaaaaa agaatagcga
    24361 gaaagataac taaaatactg gtaaaatatt gaatcttctt aaaatcatat tgaacgttca
    24421 tgctatctcc cttgctagaa tatgttttaa tctgatacta tataaatctg agac
//
LOCUS       DAVKUR010000028        24031 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKUR010000028 DAVKUR010000000
VERSION     DAVKUR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.028"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            186..416
                     /gene="blpU"
                     /locus_tag="VW749_001283"
     CDS             186..416
                     /gene="blpU"
                     /locus_tag="VW749_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0175317.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1131..3284
                     /locus_tag="VW749_001284"
     CDS             1131..3284
                     /locus_tag="VW749_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0175318.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3297..4646
                     /locus_tag="VW749_001285"
     CDS             3297..4646
                     /locus_tag="VW749_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0175319.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4816..5523
                     /locus_tag="VW749_001286"
     CDS             4816..5523
                     /locus_tag="VW749_001286"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0175320.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5525..5668
                     /locus_tag="VW749_001287"
     CDS             5525..5668
                     /locus_tag="VW749_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0175321.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5725..9450
                     /locus_tag="VW749_001288"
     CDS             5725..9450
                     /locus_tag="VW749_001288"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0175322.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9543..10985
                     /locus_tag="VW749_001289"
     CDS             9543..10985
                     /locus_tag="VW749_001289"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0175323.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGVEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11204..12226
                     /locus_tag="VW749_001290"
     CDS             11204..12226
                     /locus_tag="VW749_001290"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0175324.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12223..12768
                     /gene="purN"
                     /locus_tag="VW749_001291"
     CDS             12223..12768
                     /gene="purN"
                     /locus_tag="VW749_001291"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0175325.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12852..13361
                     /locus_tag="VW749_001292"
     CDS             12852..13361
                     /locus_tag="VW749_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0175326.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13386..14933
                     /gene="purH"
                     /locus_tag="VW749_001293"
     CDS             13386..14933
                     /gene="purH"
                     /locus_tag="VW749_001293"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0175327.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15055..16317
                     /gene="purD"
                     /locus_tag="VW749_001294"
     CDS             15055..16317
                     /gene="purD"
                     /locus_tag="VW749_001294"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0175328.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16720..17208
                     /gene="purE"
                     /locus_tag="VW749_001295"
     CDS             16720..17208
                     /gene="purE"
                     /locus_tag="VW749_001295"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0175329.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17195..18286
                     /gene="purK"
                     /locus_tag="VW749_001296"
     CDS             17195..18286
                     /gene="purK"
                     /locus_tag="VW749_001296"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0175330.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18296..18523
                     /locus_tag="VW749_001297"
     CDS             18296..18523
                     /locus_tag="VW749_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0175331.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18586..19884
                     /gene="purB"
                     /locus_tag="VW749_001298"
     CDS             18586..19884
                     /gene="purB"
                     /locus_tag="VW749_001298"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0175332.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19939..23877)
                     /gene="strH"
                     /locus_tag="VW749_001299"
     CDS             complement(19939..23877)
                     /gene="strH"
                     /locus_tag="VW749_001299"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0175333.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLETLDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
BASE COUNT         6593 a         4742 c         5749 g         6947 t
ORIGIN      
        1 tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa
       61 agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac
      121 tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat
      181 tcgttatgaa tacaaaaacg atgtcacaat ttgaaattat ggatactgag atgcttgctt
      241 gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag
      301 cagtacgagg tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg
      361 ctgcgggagg agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat
      421 ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt atatggatga
      481 tttaattaga aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa
      541 ataatcaaaa ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag
      601 tcttatagta acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc
      661 tattctgact aggaatagat cataccagag gtagcttaga aatagcaggg acattagaaa
      721 ttgaagtaat aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt
      781 gcctagggtg acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac
      841 tcttgttctg cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg
      901 ggaaggaagt ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt
      961 atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact
     1021 gacttcgtca gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt
     1081 cctagtttgc tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg
     1141 ggaaacgtca ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca
     1201 tggtttttgg ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga
     1261 cgaccatgga tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg
     1321 agacgcgagc cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt
     1381 ttgttgccca tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg
     1441 ataaggatag cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac
     1501 gtgagcgttt tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact
     1561 ataagcctta taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc
     1621 agcgtggctt gattgccaat atcgttttgg caacactctt ggtaaccggg attaacattg
     1681 tgggttctta ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga
     1741 cactagggat tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt
     1801 acgctcagga gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt
     1861 cctatatcaa gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg
     1921 agatcgtgtc tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc
     1981 tttcgatttt cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa
     2041 ataccaatct ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg
     2101 cctttatgaa gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt
     2161 cttcttctat cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa
     2221 gtcagcgtta ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct
     2281 atagtcgagc agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg
     2341 tcggcattct ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt
     2401 tgattaccta taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc
     2461 tgcaaaccaa gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag
     2521 tagcttctga gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata
     2581 tgaccttcaa gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca
     2641 atttaaccgt tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga
     2701 cgactttggc caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg
     2761 gtggtgtcaa tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc
     2821 ctcaacagcc ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg
     2881 aggggacgac acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata
     2941 tcgagcgcat gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag
     3001 gtggtcaacg tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga
     3061 ttttggatga ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc
     3121 tcatggcttt ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga
     3181 cagagaaggt agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt
     3241 tgcttgcaca gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga
     3301 aaccagaatt tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta
     3361 gtgtgattgt acccatggcc cttctgcttg tgtttttact tggctttgca actgttgcag
     3421 agaaggagat gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc cttgcaaata
     3481 tccagtcaac tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta
     3541 agaaggggga tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct
     3601 atgccagtca gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga
     3661 gcctgcaaga aggggagaac cactttccag aggaggataa gtttggctac caagccacct
     3721 ttcgcgacta catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga
     3781 ccatcgcgtc ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca
     3841 gtcaaacaga ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg
     3901 cttccttggc cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg
     3961 aggaaaatcc ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt
     4021 tagaatctag tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct
     4081 atgcgtcagg gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg
     4141 gtcaggaatt gacccttcta gcccagaaaa ttttggaggc agagtcaggt aagaaggtac
     4201 agggaaatct tttagacaag gggaaagtta cggcgagtga ggatggggtg cttcatctta
     4261 atcctgagac cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc
     4321 catctttgga aagagaaggg aaagccaaac tcacagctta tctaagttca aaatatgtag
     4381 caagaatcaa ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac
     4441 ttttcctaga ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga
     4501 atttctttaa aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt
     4561 acggggtgga aggccgcttg cagatgatta cgggcaagaa aagttaccta cgttattatt
     4621 tggatcaatt tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac
     4681 tgtgagaaag attcttcttg cagttttttc tttacaattt ttgaaaaaca tctactattt
     4741 attcggttaa attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga
     4801 aaggcgaact ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat
     4861 acaactgagg atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac
     4921 ggtgtcaaga aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt
     4981 atttttgaga aattaaatgt ggctggtgtg gcgactcact ttgtggagaa actttcagac
     5041 acggaacaac tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat
     5101 actgctggtt ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg
     5161 attgtcgaat tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat
     5221 gtgaaattcc tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt
     5281 cgtatcaatg aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt
     5341 aagctagagt tcggttttga caaggatggc aagattatct tggcagacga attttcacca
     5401 gataactgcc gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga
     5461 ggattgggag aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa
     5521 taatctgttt gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt
     5581 cccccagacc ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt
     5641 ctgggaaaag ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga
     5701 gctgaaataa aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat
     5761 tttcaggtca agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc
     5821 ttgaaaagta ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt
     5881 gcacctgcag agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta
     5941 tctgtgcagg cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag
     6001 tttgaccagc gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac
     6061 gtgacagtca acacagccca actttacttg gtgaataaag atattgatgc gactgagttg
     6121 gaagctgtca aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca
     6181 gggattgcca agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt
     6241 gaaagctata cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa
     6301 gtggatgatt tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag
     6361 actgaactca aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag
     6421 acagagttga aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc
     6481 tatgacaagt atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg
     6541 atggatatgg cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg
     6601 gaagtctctg acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc
     6661 aaggaacctt ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag
     6721 ccatttggtg gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt
     6781 tcctatgttt accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg
     6841 gaaactcgtg ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat
     6901 tcttcatatg gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca
     6961 ggctttgtag ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat
     7021 gttgtccgtg aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt
     7081 cgtgatggtg tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag
     7141 actgctggtg ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc
     7201 ttccgtaatg gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc
     7261 gtctgtgtgg ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct
     7321 cttaaatacc agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg
     7381 gcggtcgtgg ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat
     7441 attgatgctg ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat
     7501 ggtgagacaa tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt
     7561 gtcgatgcca aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct
     7621 gaaacactgg aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa
     7681 ggattacaga ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt
     7741 ggtcgttacc aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt
     7801 gtgactcata ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct
     7861 ccataccacg gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt
     7921 gccaactggt ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa
     7981 gcagagcgtt tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag
     8041 cttggcttgc catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc
     8101 gttccgccaa ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct
     8161 ccagaattta aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca
     8221 gagattgatt ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac
     8281 cataaagtga cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt
     8341 gctacctttg gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg
     8401 acagctcaat taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag
     8461 attggacaaa cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac
     8521 aagcttgaca gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa
     8581 gcgaaagaac tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa
     8641 aaggttgaaa aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat
     8701 tcagctaagg ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg
     8761 aatgaagaag ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat
     8821 attctcttct ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt
     8881 atcgtcaata tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt
     8941 ggtggcttga ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta
     9001 ccatacggaa actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc
     9061 aaccaacacg tggccaagat ggtggaaact cgtattgcca ataccaactc accatggttg
     9121 gctggtgtgc aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt
     9181 gtcgtgacgg ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac
     9241 gttgacttta acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat
     9301 gccatcgaag gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa
     9361 cgttatgagg atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca
     9421 tcagcggtta aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca
     9481 gtaatgtaaa agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa
     9541 aaatgacata cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac
     9601 atccagatgc tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg
     9661 agggggcagg aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc
     9721 ttttatcaga agttttcaga aatccagcca atttggataa attgacagga gctggtgcga
     9781 ttgggcatgt gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc
     9841 tcttccgttt tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag
     9901 cctctctcaa gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg
     9961 aaatcttggc tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg
    10021 aagcgctcag ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga
    10081 ttgcggctct tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag
    10141 cggtggttgt ttcctctgaa acctgtgctt ttgaggtcat tggtgtcgag tggatttgtg
    10201 atttgaagcc aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata
    10261 cagatgatac ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt
    10321 ctaatatcca cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc
    10381 gagaatttaa gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg
    10441 ctatgggatt tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat
    10501 acacccagcg aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga
    10561 aactgtctgc tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca
    10621 ttgtacgtgg aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg
    10681 aggttcacgt tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata
    10741 tccagacccg tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca
    10801 ttggtgcgga cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg
    10861 aaacagatgc gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc
    10921 ctctctatga ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca
    10981 agtaggcgac agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat
    11041 atgcctcacg tctcactact gactaaaggc ttaagcattt agtcagtaga cgctttgtcc
    11101 tataggatca aagctagagc cctgactagt atttttagat aaaaagatgg tttatctaaa
    11161 aatacgtcgc agtctttctc aaaaaaagaa aaggaaaaat aaaatggcaa ataaaaatgc
    11221 gtacgctcaa tctggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa
    11281 gcacgtggct cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat
    11341 gtttgacctt tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt
    11401 cggaaccaag ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg
    11461 tgtggccatg tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga
    11521 ctacgtagcg acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc
    11581 agaaggttgt gtgcaggctg gtgctgccct catcgctggg gaaacggctg aaatgccggg
    11641 catgtacggc gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc
    11701 tcaaatcatt gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag
    11761 tgggattcac tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga
    11821 ggaagtccta ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg
    11881 tatctatgtc aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca
    11941 catcacaggt ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc
    12001 tgaaattgat gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg
    12061 tcagattaaa cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc
    12121 ggtcagccct gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat
    12181 tggtcgcatc gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt
    12241 tttgcctctg gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt
    12301 gtcttttcag accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg
    12361 tcctatgctt ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc
    12421 gaactcttgg aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt
    12481 ggaccaacct tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg
    12541 ccagaatttc caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct
    12601 ggtgtgacca ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt
    12661 cgtgtgccac gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca
    12721 gagtacaggt tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat
    12781 tcatatgata tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg
    12841 aggtatttgt aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga
    12901 tgttattaac ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt
    12961 tcttagctcc aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa
    13021 aaattgtttt tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt
    13081 tccctttgat aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta
    13141 gtttattgtt tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt
    13201 tgactttaaa tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag
    13261 tgttcaaatc acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg
    13321 cttatcttgt tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga
    13381 atataatgac taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg
    13441 cccaagaact aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc
    13501 ttgataatgc tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga
    13561 tggatggccg tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg
    13621 atttggatag ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag
    13681 tggtcaacct ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg
    13741 cagttgaaaa tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg
    13801 ccagtgttac agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag
    13861 caaacggcga aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca
    13921 cagcggctta tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc
    13981 ctgaaaaact cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc
    14041 aacaagacgc ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca
    14101 aacagctcaa cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc
    14161 gtatcatccg tgacttcaaa gatagtccaa ccgttgtggc tctcaagcat atgaatccat
    14221 gtggtatcgg ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc
    14281 cagtgtctat ctttggtggt atcgttgttc ttaaccgtga ggtggatgct gcgacagctg
    14341 agaagatgca cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc
    14401 tagctatttt gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc
    14461 aagaggctag cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa
    14521 atcaagacgt ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa
    14581 ccgagacaga agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa
    14641 atggtattat cgtgaccaac gatcacatga cacttggtgt tggtccaggt caaaccaacc
    14701 gtgtggcttc tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc
    14761 ttgcttcaga tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa
    14821 ttaaggccat catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg
    14881 ataaatatgg cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata
    14941 aaagggaaga aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta
    15001 aaacgaactt ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa
    15061 ctgcttgttg tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca
    15121 aaagacgtgg aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg
    15181 gaattggtaa atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat
    15241 gatgttgctt ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat
    15301 tttaaccaag ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg
    15361 tccaaggatt tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc
    15421 acattttcag atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta
    15481 gtcaaggcgg atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa
    15541 gcggtcgaag ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc
    15601 gtggttattg aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt
    15661 gataagttct acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa
    15721 gggcctaaca cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta
    15781 gttgatacag cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt
    15841 cgcccttatc tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc
    15901 attgagttca acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc
    15961 tctgactttg ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg
    16021 acggacaagg gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat
    16081 gaaaggggcg ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg
    16141 gctaagtttg cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc
    16201 gttaccacag cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa
    16261 caaaaaatag aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga
    16321 tataagaata acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca
    16381 gaacagtgaa tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat
    16441 gaaaccgaag gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa
    16501 aattcacaaa atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac
    16561 aatcaccgcc gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa
    16621 gaccttgggt ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa
    16681 gctaaggtga ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc
    16741 atcatgggct caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc
    16801 ttcggtgtag cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc
    16861 aaacatgcag aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc
    16921 gcagcgcatt tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca
    16981 gtcaagtctc gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt
    17041 ggggtgcctg ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt
    17101 gccctccgtc tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct
    17161 gaagaacaag gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat
    17221 tatcggtggc ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa
    17281 ggttatcgcg ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt
    17341 ggcaccttat aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac
    17401 ttacgagttt gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact
    17461 ccctcaagga acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt
    17521 gtcaaacaag gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt
    17581 ggcagatatc gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg
    17641 tcatggacaa aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga
    17701 ctcagcagac tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt
    17761 gtcaggaaat ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa
    17821 tatcctgtct aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa
    17881 agctatggca gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat
    17941 gtttgcgact gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg
    18001 gcactattct attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct
    18061 cggagcacca ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg
    18121 tcagcatgtc gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat
    18181 gtatggtaaa atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga
    18241 tgtaccggat agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat
    18301 acaaattatc gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt
    18361 gtatgccagt gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata
    18421 ccccgaaaat tatttagcta tctatgatgt accgctggat acggatttga atacactaga
    18481 tcattacccg tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta
    18541 gatagcttat tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac
    18601 tctcgccctg agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag
    18661 gtggaaatcc tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg
    18721 gctttgattc gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag
    18781 acgcgccacg atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc
    18841 aagtgggttc actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc
    18901 tacaagcagg ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct
    18961 gacaaggcca aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct
    19021 gagccgacaa cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc
    19081 gagcgtttcg agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg
    19141 aactttgcca atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt
    19201 gcccaagaaa tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt
    19261 cttgccagca ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa
    19321 tctgagcaac gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg
    19381 cctcacaaac gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt
    19441 ggtcacatga ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac
    19501 tcatcagctg agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac
    19561 cgttttggaa atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg
    19621 aactcgactt ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc
    19681 atgacccgtg agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac
    19741 caagtagact ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa
    19801 gaagaaatcg atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt
    19861 gaacgtcttg gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt
    19921 attttttatc gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt
    19981 ggacatgagt cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt
    20041 tttctctgtt accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc
    20101 agttgatgga gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc
    20161 ttgtccgttt tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac
    20221 ggcttcctgt gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt
    20281 gctcacagag tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt
    20341 tcctttgagt aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg
    20401 gatatccagt ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg
    20461 agttacagga gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc
    20521 aaggactgtt tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc
    20581 acctttgact cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt
    20641 cttgataact tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac
    20701 attggcagcc acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc
    20761 ttgaagagcg gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt
    20821 gaggttgtaa tttagagctg ttttagctgc gtcaagggtc tcaagacttt ctttactata
    20881 tccttctaag tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg
    20941 gaagtagtct ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt
    21001 gtattcagcg cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc
    21061 tacttcagga tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat
    21121 agctttcttg aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc
    21181 accgttggta ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt
    21241 atatccccac cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc
    21301 gtccttgtct tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt
    21361 ggccatagct gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt
    21421 gaggtagtac cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt
    21481 gaaaatcttt gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa
    21541 gttcatcgct tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc
    21601 ttgaggattt ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg
    21661 actgttaata gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt
    21721 tacttctgcc tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc
    21781 gataatagct tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat
    21841 atcatcgagt agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc
    21901 gagctcactg gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc
    21961 agcatcgatt gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc
    22021 ttctttttga gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat
    22081 ggcttgatca atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc
    22141 tttttcagct tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg
    22201 tacctcgtta agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc
    22261 atttgcaaaa tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt
    22321 gtcagcccaa gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg
    22381 tacagaagtg attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc
    22441 ttggccatca gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg
    22501 gtgacctttt tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt
    22561 ccacatagaa acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta
    22621 gataccgtcg ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc
    22681 attggcgtag gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta
    22741 tttatcagct tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc
    22801 aagtccgatg ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag
    22861 ggcttttgta aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt
    22921 cccaaaatag ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc
    22981 atccatgtgt ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata
    23041 gttaatcaga tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata
    23101 atcatttgta cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt
    23161 agctgtgatg ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg
    23221 taaatcagtg tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga
    23281 gaaatattta cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac
    23341 agttgcagca cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc
    23401 atctttttta gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac
    23461 ctctttcgct tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt
    23521 ttcagcagaa gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc
    23581 ttgtggtttt tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt
    23641 ttctacagtt tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt
    23701 ttcggatgat tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt
    23761 aggagtaact ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga
    23821 agctgctcct acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc
    23881 aaaacctcct gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt
    23941 atttcttata ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa
    24001 atataaaatt taaacttaag atttcagatt g
//
LOCUS       DAVKUR010000029        23126 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKUR010000029 DAVKUR010000000
VERSION     DAVKUR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.029"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            168..1649
                     /locus_tag="VW749_001300"
     CDS             168..1649
                     /locus_tag="VW749_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0175334.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2011..3012
                     /locus_tag="VW749_001301"
     CDS             2011..3012
                     /locus_tag="VW749_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0175335.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3163..4080
                     /locus_tag="VW749_001302"
     CDS             3163..4080
                     /locus_tag="VW749_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0175336.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4091..4981
                     /locus_tag="VW749_001303"
     CDS             4091..4981
                     /locus_tag="VW749_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0175337.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5010..6626
                     /locus_tag="VW749_001304"
     CDS             5010..6626
                     /locus_tag="VW749_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0175338.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6636..7955
                     /locus_tag="VW749_001305"
     CDS             6636..7955
                     /locus_tag="VW749_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0175339.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8167..8239)
                     /locus_tag="VW749_001306"
     tRNA            complement(8167..8239)
                     /locus_tag="VW749_001306"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8204..8206),aa:Lys,seq:ctt)
     gene            complement(8504..9775)
                     /locus_tag="VW749_001307"
     CDS             complement(8504..9775)
                     /locus_tag="VW749_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0175340.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10045..10245
                     /locus_tag="VW749_001308"
     CDS             10045..10245
                     /locus_tag="VW749_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175341.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10449..10628
                     /locus_tag="VW749_001309"
     CDS             10449..10628
                     /locus_tag="VW749_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175342.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10765..10944
                     /locus_tag="VW749_001310"
     CDS             10765..10944
                     /locus_tag="VW749_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0175343.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10981..11433
                     /locus_tag="VW749_001311"
     CDS             10981..11433
                     /locus_tag="VW749_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0175344.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11724..12194
                     /locus_tag="VW749_001312"
     CDS             11724..12194
                     /locus_tag="VW749_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0175345.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12213..13301
                     /locus_tag="VW749_001313"
     CDS             12213..13301
                     /locus_tag="VW749_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0175346.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13282..13440
                     /locus_tag="VW749_001314"
     CDS             13282..13440
                     /locus_tag="VW749_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV0175347.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13550..14584
                     /locus_tag="VW749_001315"
     CDS             13550..14584
                     /locus_tag="VW749_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0175348.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14646..16829
                     /locus_tag="VW749_001316"
     CDS             14646..16829
                     /locus_tag="VW749_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV0175349.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16880..17896
                     /locus_tag="VW749_001317"
     CDS             16880..17896
                     /locus_tag="VW749_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0175350.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            17911..18861
                     /locus_tag="VW749_001318"
     CDS             17911..18861
                     /locus_tag="VW749_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0175351.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVLA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18863..19606
                     /locus_tag="VW749_001319"
     CDS             18863..19606
                     /locus_tag="VW749_001319"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0175352.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19617..21413
                     /gene="pepF"
                     /locus_tag="VW749_001320"
     CDS             19617..21413
                     /gene="pepF"
                     /locus_tag="VW749_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0175353.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            21660..22214
                     /locus_tag="VW749_001321"
     CDS             21660..22214
                     /locus_tag="VW749_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0175354.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            22325..22993
                     /locus_tag="VW749_001322"
     CDS             22325..22993
                     /locus_tag="VW749_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0175355.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7341 a         3798 c         4892 g         7095 t
ORIGIN      
        1 ccctcaatag acggtaaaat aagaaaattg tttatatatt gtctccgtag tgttattata
       61 cgaaataaaa gattttagga aaagtcgtta tatcatgcta tacctattct ttgtggtata
      121 attgcaagag gtttaatccg ataatttata aagagagaaa gatattcatg agagatttat
      181 tatctaaaaa aagtcatagg caattagaat tattagaatt attatttgaa cataaacgtt
      241 ggtttcatcg ttctgaacta gcagagttat taaattgtac agaacgtgca gtcaaagatg
      301 atctatccca tgttaaatct gcttttcctg acttgatttt tcattcttct actaatggta
      361 tacgcattat taataccgat gatagtgata ttgaaatggt ttaccatcat ttctttaaac
      421 attcaactca tttttcgatt ttagaattca tcttctttaa tgaaggttgt caagctgaga
      481 gtatttgtaa agaattttat atcagttcat cttcgctcta tcgtattatt agccaaatca
      541 ataaagtgat taaaaggcaa tttcaatttg aagtcagtct gacccctgtt caaatcattg
      601 gaaatgagag agacattcgt tacttttttg cacaatattt ttcagaaaaa tattatttcc
      661 tagaatggcc atttgaaaat ttttcatcag agccactatc tcaattgtta gaattggttt
      721 ataaggaaac aagctttcca atgaatttgt caacgcatag aatgctaaag ttgctcctag
      781 ttacgaacct atatagaata aagtttggtc attttatgga agtagataaa gattctttta
      841 acgaccaaag tttggatttt ttaatgcagg cagaaggaat agaaggtgtt gctcagagtt
      901 ttgaatcaga atacaatatc tctttagatg aagaagttgt ttgccaatta tttgtgtctt
      961 actttcaaaa aatgtttttc atagatgaaa gtctctttat gaaatgcgta aaaaaggata
     1021 gttatgttga aaaatcttac catctattga gtgattttat tgatcagatt tcagtcaagt
     1081 atcagattga aatggagaat aaggataatc tgatttggca tctgcataat accgcacatc
     1141 tgtatcgtca agagttgttt actgagttta ttttatttga tcaaaaaggg aatacaatca
     1201 ggaactttca aaatattttt ccaaaatttg tttcagatat aaaaaaagag ctttctcact
     1261 atttagagac tcttgaggtt tgttctagtt caatgatggt aaatcatcta tcttatacct
     1321 tcatcactca taccaaacat ttggtgatta atttgctaca aaatcagcct aaactaaagg
     1381 ttttagttat gagtaatttt gatcagtatc atgcaaaatt cgttgcagag acactttctt
     1441 attactgtag caataatttt gaactggaag tttggactga attagaatta tcaaaggaat
     1501 ctttagaaga ttcaccttat gatatcatta tttctaattt tattattcct cctattgaaa
     1561 ataagagact catctattca aataatataa acacggtctc actcatatac ttgttaaatg
     1621 ccatgatgtt tattcgatta gatgagtaac caaaaataac aaaaaaacgc tatttcgcgt
     1681 ttgaactgta cctcaaaagt tagacagaaa aaatctaatt tttggggtgt ttttgttaag
     1741 aaaagacctt caatcattta agcaaaatgt acatctagat ttatagccct ctaaaactct
     1801 tgcttttttt gtagaagata cgaaaaaagc cataaaacca aggcttttcc tgttttatgt
     1861 agatgtttac acatgaaaat tgaagtattt tcaaaagcta attggagtga ttttattcat
     1921 gatgggataa atgatctggc caaaaatgat tgagaaatag ttgcttaaaa agcatttgca
     1981 tgatactata tattgaaagg aggtgataat atggtagaac aaagaaaatc aattaccatg
     2041 aaagatgttg ctttagaagc aggagttagt gttggaactg tttcacgtgt aattaataaa
     2101 gaaaaaggca ttaaagaagt aactttgaaa aaagtggaac aagcgattaa aactttgaat
     2161 tacattccag attactatgc tagaggaatg aaaaaaaatc gaacagaaac gattgcaatc
     2221 attgtaccaa gtatctggca tcccttcttt tcagaatttg ctatgcatgt ggaaaatgaa
     2281 gtctataaga gaaataacaa attactctta tgttctataa atggtacaaa tagagagcaa
     2341 gactatctgg agatgttgcg tcataataaa gttgatggag tggttgccat tacctatagt
     2401 ccaattgaac attacttgac gtcaggaatt ccctttgtta gtattgaccg cacatactca
     2461 gatattgcca ttccttgtgt ttcatcagat aatgatgcag gtggaagaga agcagctaaa
     2521 caattaatta gtaaaggatg tcagcattta gcctttgtgg gcggacataa tacaaccatt
     2581 aatgaaacca aacgtcgtag aatttcattt gaaaagtatg tccaagagca taaaatacct
     2641 cttagtattt ttgatttgga tgagacagtt actgactatt atggaaagct agagagtttc
     2701 ttggaagaaa attcttctat agatggaatt tttacaatca acgattttac agctttggat
     2761 gtgattgaaa tactagaaaa aaatggcaaa cgtattcctc atgatgtcca aattattgga
     2821 tacgatggaa ttaaaatggc tggagataga gattatctac tttcaactat tgaacaacca
     2881 ttggaagaaa tggcaaaaga agcggttcgt attttgtttg atataattga tggaaagact
     2941 gttaatttgc agacaatcct accagtaaaa tttgttgaag gaaaaacaac aaaaaatgaa
     3001 aataagtctt gacagaaagc gctatcaatg atagaatgaa ttcagataaa aagatttatt
     3061 tttaaaacaa aaatgaaacg tttcaaaaaa agaaataaaa agacagcgcc aagcgctatc
     3121 ttttatagaa aaaatgaaac gtttcaaaaa aaggaggttg ctatgaatag caaagcgaag
     3181 caagtttctc tttgggaaag aatcaagaaa caaaaactct tgttattgat gactgtcccc
     3241 ggtttagttt taacctttat ctttaaatac atccctatgt atggggtttt aatcgcattt
     3301 aaagattaca atcctttaaa aggaatttta gggagtgatt ggattggttt ttctgagttt
     3361 acaaaattca tatcctctcc caactttggt atcttgttag ccaacacatt aaaattaagt
     3421 atctatggtt tattgcttgg ctttttacca ccaatcattc ttgcgattat gctcaatcaa
     3481 ctcttgagtg aaaaagtcaa aaaacgaatt cagctcattt tatacgcacc aaactttatc
     3541 tcagtcgttg ttattgtcgg tatgattttc ctcttctttt cagtgggagg accaatcaac
     3601 aattttcttt ctatgtttgg aatgaaggct gacttcttga caaatccaga cttctttaga
     3661 cccttataca tctttagtgg tatctggcaa ggaatgggct gggcttcaac gctctacacg
     3721 gcaacattgg taaatgtaga tccagcctta gtagaagcag ctcgactgga tggagccaat
     3781 atcttccaac gaatctggca cattgatatt ccagctctta agcctattat ggttatccaa
     3841 tttgttttag ctgcaggtgg aattatgaat gtcggatatg aaaaagcatt cttgatgcag
     3901 acatcgttaa atttgccaac ttctgaaatt atctcgacat atgtctataa agttggtctt
     3961 gtatcaggag actattctta ctcaacagcg gttggtttgt ttaatgcagt gattaacgta
     4021 gtattgcttg ttgcagttaa ccaaatcgtt aaacgcatga ataatggtga aggaatttaa
     4081 ggaggaaagt atgaaaaatt cgattatgga tacaaaattt gatagacgta tcttactctt
     4141 aaataaaatc attattgtct ttatcgtttt gatgactttg cttcctttac tttatatcgt
     4201 cgtagcatcc tttatggatc ctaaggttct ggttagtaga gggattagct ttaatccagc
     4261 cgattggact gtagaaggtt accagcgtgt attcagtgac caatctattc taagaggttt
     4321 tatcaattct ctactatact cttttggatt tgcagcttta acagtattgc tatctgtgtt
     4381 tacagcttat cctctttcta agaaagactt ggttggacgt cgttggatta actacttctt
     4441 gattgtgact atgttctttg gtggtggttt agtcccaact tacttgctcg taaaagaatt
     4501 gggaatgctc aatactccat gggctatcat tgttccaggt gctgtcaatg tttggaatat
     4561 tattcttgct agggcctatt tccaaggatt gcctgaagaa ttagttgaag ctgctgtcat
     4621 tgatggagcg aatgacttgc agattttctt taaaatcatg cttcctcttg caaaaccaat
     4681 tatgtttgtt ctcttcctct atgcttttgt aggacagtgg aactcatact ttgatgcaat
     4741 gatttatatc aaggatccaa acttggaacc attgcaactt gtacttcgta aaattctcat
     4801 tcagagccaa ccaggtcaag acatgattgg agcacaagcg gctatgaatg aaatgaaacg
     4861 tttagctgaa ttgattaaat acgcaactat tgtcatttcc agcttgccat tgattgttat
     4921 gtatccattc ttccaaaaat actttgataa aggaattatg gctggttcac ttaaaggata
     4981 aaaaaagaaa aaataaaagg agttttctca tgaaattcaa aacattctca aaatcagcag
     5041 ttttgttgac agctagttta gcagtacttg cagcctgtgg ctcaaaaaat acagcttcaa
     5101 gtccagatta taagttggaa ggtgtaacat tcccgcttca agaaaagaaa acattgaagt
     5161 ttatgacagc cagttcaccg ttatctccta aagacccaaa tgaaaagtta attttgcaac
     5221 gtttggagaa ggaaactggc gttcatattg actggaccaa ctaccaatcc gactttgcag
     5281 aaaaacgtaa cttggatatt tctagtggtg atttaccaga tgctatccac aacgacggag
     5341 cttcagatgt ggacttgatg aactgggcta aaaaaggtgt tattattcca gttgaagatt
     5401 tgattgataa atacatgcca aatcttaaga aaattttgga tgagaaacca gagtacaagg
     5461 ccttgatgac agcacctgat gggcacattt actcattccc atggattgaa gagcttggag
     5521 atggtaaaga gtctattcac agcgtcaacg atatggcttg gattaacaaa gattggctta
     5581 agaaacttgg tcttgaaatg ccaaaaacta ctgatgattt gattaaagtc ctagaagctt
     5641 tcaaaaacgg ggatccaaat ggaaatggag aggctgatga aattccattt tcatttatta
     5701 gtggtaacgg aaacgaagat tttaaattcc tatttgctgc atttggtata ggggataacg
     5761 atgatcattt agtagtagga aatgatggca aagttgactt cacagcagat aacgataact
     5821 ataaagaagg tgtcaaattt atccgtcaat tgcaagaaaa aggcctgatt gataaagaag
     5881 ctttcgaaca tgattggaat agttacattg ctaaaggtca tgatcagaaa tttggtgttt
     5941 actttacatg ggataagaat aatgttactg gaagtaacga aagttatgat gttttaccag
     6001 tacttgctgg accaagtggt caaaaacacg tagctcgtac aaacggtatg ggatttgcac
     6061 gtgacaagat ggttattacc agtgtaaaca aaaacctaga attgacagct aaatggattg
     6121 atgcacaata cgctccactc caatctgtgc aaaataactg gggaacttac ggagatgaca
     6181 aacaacaaaa catctttgaa ttggatcaag cgtcaaatag tctaaaacac ttaccactaa
     6241 acggaactgc accagcagaa cttcgtcaaa agactgaagt aggaggacca ctagctatcc
     6301 tagattcata ctatggtaaa gtaacaacca tgcctgatga tgccaaatgg cgtttggatc
     6361 ttatcaaaga atattatgtt ccttacatga gcaatgacaa taactatcca agagtcttta
     6421 tgacacagga agatttggac aaaattgccc atatcgaagc agatatgaat gactatatct
     6481 accgtaaacg tgctgaatgg attgtaaatg gcaatattga tactgagtgg gatgattaca
     6541 agaaagaact tgaaaaatac ggactttctg attacctcgc tattaaacaa aaatactacg
     6601 accaatacca agcaaacaaa aactagaggt tgattatggg agataagaaa tacacagtag
     6661 aaaaagccaa tcgttttata gcagaaaata aacatctcgt taatactcaa tataagcctg
     6721 aagaacattt ttcagctgag attggttgga tcaatgatcc aaatggattt gtctattttc
     6781 gtggagaata ccatctcttt tatcaattct atccatatga tagtgtttgg gggcctatgc
     6841 actggggaca tgctaaaagt aaggacttgg tgacttggga gcacttgcca gtggcacttg
     6901 ctcctgacca agattatgac cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg
     6961 atcgcctctg gctcatgtac actggacata tcgaagaaga aaccggtgtc cgccaagtgc
     7021 aaaatatggc attttcagat gacgggattc actttgaaaa gatttcccaa aatccagttg
     7081 caactggatc agacttgcca gatgagttga ttgctgctga tttccgtgat ccaaaactct
     7141 ttgaaaaaga tggacgctat tactccgtag tagctgccaa acataaggat aatgtgggct
     7201 gtatcgttct actagggtcc gataacctag tagaatggca gttcgaatcc atctttttaa
     7261 aaggggtaga acaccaaggc tttatgtggg aatgcccaga ttacttcgag ttagatggga
     7321 aagattgcct tattatgtca cccatgcgtt atcagcgtga gggagactca tatcataaca
     7381 tcaactcatc gcttttgttc acgggtaagg tagattgggg agaaaaatgt tttatcccag
     7441 aatcagttca agaaattgat catggccaag acttctatgc gcctcaaaca ttgttggacg
     7501 atcaaaatcg tcgtatcctg attgcttgga tgcagacatg ggggcgtacc cttccaaccc
     7561 atgaccaaga acacaaatgg gcatgtgcca tgactttacc tagaatttta agattggaag
     7621 atggcaaact aagacaattc cctgttaaaa aaggccaata tcaaatccaa atagataaag
     7681 attgtcatta ccacttagga aatgatatag attatcttga atttggttat gatagtaatg
     7741 cgcagcaagt ttacattgat cgtagccatc ttattcaaaa aattctaggt gaagaagaac
     7801 aggacactag tcgacggtat gtagatattg aagctaaaga attggaagtt gttctagata
     7861 aaaattccat cgagattttt gtcaatcaag gtgaagcaag cttgactgca acttattact
     7921 taacggtgcc agctgagcta tcacgaattg attaaaaatt aagttatttc tcctaaagaa
     7981 aaagttctct ttctaaaata gtggaaagag gactttttgt gttttgggta tataagctta
     8041 gtttatggta tttgtaaaat tggtgttgga ttatgattta agctagtttt ctaaagaatt
     8101 tgaaaaaaat tttatttaag caaaaaaaaa acccttggtt ccaaggcttt tcctgttgta
     8161 tttatatgcc ccctacaggg atcgaacctg tgacccacgg attaagagtc cgctgctctg
     8221 ccagctgagc taaggaggca aagaaaaaag ctgtattggt gccgaaactt cacggtttgt
     8281 attgaacccg cgcaattaag caggtgggca actcgctcta actgaagctg tttccgtgtg
     8341 agacggccta catgctgtta gaagactttt gtttccctaa taatacaaaa aatagtcggt
     8401 caacacttaa gtgtgaagtc gtacaccaca gcgtttctat acttatatga taccactttt
     8461 tcaaaaaaaa tcaagaggaa agtgcaattt tttgaaaagg atttcagatt tttcgcaaac
     8521 ggtcgatagc ttcctttctt tgagccaaag cccgttcata tttaccagta tcttctgctt
     8581 ggaaatagtg atgattacga attttttctg gcagatagtc ttgcttgacc caatttccag
     8641 gatagttgtg tggatagaga tagtcttggg cattccccag ttccttgctt ccactgtagt
     8701 gcccatcacg taggtgtcgc ggaataggca agtgccctga tgttttgagg tcagcaagtg
     8761 ccttatccat agctacatag gctgagttgg attttggaga aagggccaaa tcaatcacga
     8821 cattggcaat gagaatgcgg gcttctggga acccaatctt ctgggcagca tccagagcag
     8881 tcacggtatg aatctgggcc tcaggattgg ctaagccgat atcttcatag gcgataacag
     8941 tcaagcgacg agcgagacta ggcagatccc cagcctcaat caagcgggca gtatagtgga
     9001 gactggcatc cacatctgag ccacgaatag acttttgcag ggcagataga acatcatagt
     9061 gaccgtctcc atccttgtcc atagtgatgt agcttctctg aagactattt tccatgatgt
     9121 ctaaggtgat gtggcgaatg ccctcgtcat tctcaggggt agagagaaca gctaagtcca
     9181 gtgagttaaa ggcagagcga aggtctccgt ttgtagaggt tgcgatgaaa tccagcgcat
     9241 cctcatctag ttctattgga aaatcaaaac cacgttcagg gttacttaga gctatctgca
     9301 gggcctcttt gacgtcttgg ttagacagag gttccaactc gaaaatttga actcggctac
     9361 gaatggcagg agtgacagag aagaaaggat tttcagtcgt tgctccaatc atgatgacca
     9421 gtccactttc caagagaggc aagaggaagt cttgcttggt cttatctagt cgatgaattt
     9481 cgtctagcaa taggacgaga ccaccagaaa atttagcttc ttccgagatt tcttgcagtc
     9541 gctttttact atcaactgtc gcattgaaag ttcgaaaggc atacttggtc gttccagcga
     9601 tggcagaggc aatactggtt ttgccgattc caggagggcc atatagaatc atggaggaca
     9661 ggcggttggc ttccaccatg cggcggatga tttttccagg tccgaccaga tgctcctgac
     9721 cgatgacctg gtcgatggtt ttagggcgca tgcgaagcgc gagattgtct ggcatagcag
     9781 tcctttctag cgtggatttg agtagaatga ctcatctact atatcttact atgtccattc
     9841 tagcctatta gttgtgatat ttcaatggtt ttgtaataat cagggagtga gatagaatct
     9901 tttttactat ttaatttaat gaggagaggt atcagcatga gagatttgat tttccttaaa
     9961 gctcaaaata ggatagttga gcctaaagaa gtggaagtgc tgacttgaga aataatattg
    10021 ctgaatgtca ttgtatgaac tataatgaaa agagaggtga taagtaatgg aaatgatgga
    10081 ccaagtcagg aaattttgat ttttacaaaa caaattcgtc attggattct tagtgatcaa
    10141 gttatttcag ggaaaagaaa acttttcttc cgggaagata ctccaaaaga gattttagat
    10201 ttgtacgaaa acattaaatc taaacttgat tttgcttacc aataagttta ttctaataat
    10261 gggttgaaaa aatatgaaaa atagaataat tgatgttttt gaagtagtaa atcgcatcct
    10321 tgtaataact gttgaaaatc ctgatttcga agacttgaga gttaatcata ctcaatgaaa
    10381 atcaaagagc aaactaggaa actagccgca ggctgtactt gagtacggta aggcgacgtt
    10441 gacgtggttt gaatttgatt ttcgaagagt atcagtttgt aaaaattgga gataaaaaat
    10501 atagagtacg cagtgttcct atgattcatt caactccgcc tcaatctgtc ttagatcgag
    10561 atacttttac aattgactat acagatgatg aattgctcga taaagaagca gtttttacta
    10621 ctcattagaa aaataggtct gaataaattg gcttccctta gaaccacatc taggggcttt
    10681 tatgtataat agaataataa gtatcactcc tttacaatac gtgtaacacg tgttataatg
    10741 gtgttgtcag gaggtaaaag cgctatgcct atgacacaaa aagagatggt taaactcctt
    10801 acggcccatg gttggataaa gactagaggc ggtaaaggct cccatattaa aatggagaag
    10861 caaggggaaa gacttatcac aatccctcat ggtgagctga ataagtacac tgaaagaggg
    10921 ataagaaagc aagctgggtt gtaaaattca gcccctgttt tttgatatgg aggtagtgaa
    10981 atgttagtta cgtatccagc tttattttat tatgacgaca cagacggaac agaagcgact
    11041 tattttgtcc atttcccaga ttttgaatac tcagctacac aaggagaggg gatttctgag
    11101 gctttggcta tggggtcgga gtggctaggg ataactgttg cagatttgat agagagtgat
    11161 ggagagttac ctcagccatc agatatcaat agcttgtctt taattgataa tgatcctttt
    11221 aaagatgatg aagatttcgt gtcaacctat gaccttgata aatcttttat ttctatggta
    11281 tctgttgatg tatcagaata cctaggaagt caggaaccca taaaaaagac tttgaccata
    11341 ccaaaatggg cagataagtt gggacgagaa atgggactta acttttctca gactttgaca
    11401 gacgctattg cagataagaa agttcaagcc taagattaag cgtggtatcg tggtaatagt
    11461 caataaaaaa gcacgtccac ttgtgctagt tactcgccta ttgattttat agatttatta
    11521 gccctttcgc gggcttttta tattgatttt tatgagaaat gaagaaatca gacttttaag
    11581 aaaatcactg ataccaaggg tttaaatgag gtaatatggt ataattagga cataaaataa
    11641 ttttgtggta agatggtagt atctatttta gcatatttcc gagcaatcgg ggcgattaaa
    11701 gagtcgcata gaaagaggac aaaatggcaa catacggatt tttagatgtt ttagaggaag
    11761 agttggacaa gaactttccc tttgactttg agattagctg ggacaaacgc aaccatgcgg
    11821 tagaagtgag ttttctattg gaagcgcaaa atgctgcagg tgtggagatg gtggatgaag
    11881 acggagaggt tttatcagat gacattcttt ttgaggaagc ggtccttttc tacaatcctg
    11941 ccaagtcaac agtcaatgag gaagactatt tgactgttat tccttacctg cctaaaaaag
    12001 gattttcccg tgaattttta gcttattttg cgcttttcct taaagatact gctgaggttg
    12061 ggctagatgt cctcatggac tttttggaag acccagaagc agaggaattt gtcatggaat
    12121 ggaaccaaga agtctttgaa gaaggaaaag ttggcttgga agagggagaa ttttatcctt
    12181 atccaagata ctaggagttg gttggaggtg ttatgaagaa aattgggact tatttggttt
    12241 atgtgctagc ttttgtcttt attatgctag cttttgcttg tggaacaatc gcatttgcag
    12301 agttggggta ttccgcagtt ttagccttta cttttggtta tgccttcgct cttctaagca
    12361 tgtatttaat ctttattctt catgagctgg gtcatgcttt ttgtggctac ttgacaggct
    12421 atcggctggt ggcttttgga ttaggacatt ttattttgac caaaaagtca ggcaggtttc
    12481 atcttagtag aacagccatt ctgaaaaatg ttggtgctca atacattggt ttaaaagagg
    12541 atgaaagcga tcaaagaatc atcctgatgc tttcaggagg cttgatggtt catctcggct
    12601 tgatattatt ggcgatagtg tttggatttt tgacaagaag ctggtatttt gcagggactt
    12661 ggatttttct taatttatct ttcttcctaa ataacatttt gccagtcgac atcaccgatg
    12721 gagcaaaaat ttgggaatta ctacaacacc ctgaaaatac caaatacgcc tacctggtat
    12781 tgagacattc tgctcaaact ttgctggctc ctcaagaata tgatttgaaa gactttgttc
    12841 aagcagttcc tgaggatgca cgagggagtt ttgcggatgg tgtattaggt atgcaaggtg
    12901 aagtttccat tttggaaggg aaggaagaag tagctaaaca gcagtttcaa gcattacttg
    12961 agaggacaac tactccgatg atgcagacag ttgcccaact atccctgctt catatcgcct
    13021 tgttggaagg agattttgag caagcggagc aatatgctag tattcgacag gtcaaatcgt
    13081 ttctgtctct caaactgtcc aatcttcaag tgatacaagc ttggtatcaa tttaaggtaa
    13141 agaaagatgt agatcgaact cgtaaggctc tcaagattgc tagacagaaa atggatagta
    13201 gtcgaatgtt gagggacgag aaacgctatt atgaaaactt gttagcagag ctggaaaagg
    13261 aaatgttaga aggaactgaa gatggaacta gaaatttctg atttcccagg ctgtaagatt
    13321 gctttgtttt gtggggataa gctcttgact atcttacgtg atgataaggc aagtattccc
    13381 tgggccaata tgtgggaact gccaggtggt ggaaagagtg tcagggaaaa tctgatatag
    13441 ttttgtatta aaagaatatc ctttcaaggt tattcttttt taattttgtc ccaaaataat
    13501 tgactttgtc ccgaaaatat agtattattt gtgtaaggag gaatgaatca tgaaaaaatc
    13561 agatgttctt gatttaataa agtatcatta tgagggcaga gagacagaat ttagaaatca
    13621 atccatagca attgctcgga acttcaataa acatggtgat acacaaatag cacaatatat
    13681 tatggggtta atgtctcaaa gtgatagatt catgccacaa atagaaaatc ctagtgagta
    13741 tttgactcct gctaaactag atattggtcc tctcccattg cctctttcaa ttatgaatga
    13801 tttaaaagga ataataaacg ctgtcaatca tcatattgga ataaataaat ttttatttgt
    13861 gggatctcca ggtactggaa aaactgaaag tgtaaagcag gtggctagac ttattggcaa
    13921 ggaattactt gtagtagatt tcagtcactt agtagatagt aagctagggc aaacagtcaa
    13981 aaacttagca actcttttta atgaaatcaa taatcttcct ttcaagcaaa attatatcat
    14041 cctatttgat gaaattgatt ccatagtgtt ggatagggtt aatcagaatg atttaagaga
    14101 aatgggacga gtgacttctg cctttttaaa ggagttggat aggctgtcac cagaaattgt
    14161 attaattgca acaacaaatc tttttgaaaa tcttgataaa gcagttacga gaagattcga
    14221 tgccataatt gactttgacc gttatactga tgaagataaa gtagaagtag ctactattat
    14281 tttaaatgag ttattaaagc aatttaagaa tgtagctaga gatttaaaat tatttaaaaa
    14341 aattatcaat agtgccaatg taataccgaa tcctggtgat ttgagaaact caataagaac
    14401 gtcattggca tttagtgacc catcagatcc gcatgattac caaaaacgcc tgctaagaag
    14461 tttgcataat ggtagaaatt tatctatttc taaattatcg aagctaggtt ttactgttag
    14521 agaaattgag attttgacag gtatttctaa gagtagtgta tcacgagagt taagcgagga
    14581 ttaaaatgaa tacattattg acattacgag gtaaaagttt tacacaaaaa tcaagaaata
    14641 atggtatggg accaataact atacccaaaa aaacaataat tacattggaa catttgaagt
    14701 atcttcattt ttcattagaa gagacgaaaa catattggga gaaaaataac attatcgatg
    14761 gtattttgat cagtatttac tataatcgaa ttgttgccaa aagtaaccgt attaatggct
    14821 atttcaatgt aggaggaggg aatccattcc ctaatgatac tattgtggga gcaaaattca
    14881 atgatgagaa gacaaaacat attgttactc attatatttc tagagatgct cttaataaaa
    14941 caataaccgt tttaagtaag ataattgaag tttttgagga acattttgat agagcgataa
    15001 catgtgagat gttttctgat tcatcaacgt ttgcttctat aaatttttcg gagtatggta
    15061 tttcaaaaag caaatttcaa cagtatttga gagattcttg ctttattgag aattttggag
    15121 ttgagcacac tactgtttct gatattcaaa attctatcgt gacattttat gatgtccata
    15181 cagacatttt tagattactg aataaattaa atattgatat ttcagaagct aatatcatga
    15241 atcagaccac ggtcttgctt gatgaaaaaa atattgaatt gctactatca aaagcgccct
    15301 atcttgtctc catgattgtg gaagattttt ctaagttatc tgtagatgat ttttctttag
    15361 ataataatga tttaaaaata aatcttccat ctccaatgaa cgaaccagtt gttggcgtta
    15421 ttgatacctt atttgacaaa agagtttact ttaatgagtg ggtagaatat catgattttg
    15481 tctcacctga tattagcaaa gatagccaag attacaagca tgggacagct gtgacttctt
    15541 taatcgttga tggagccaat ttgaacccta atctggatga tggttgtgga aattttagag
    15601 tgaggcattt tggtgtgtca ctacaaagtg gatttaattc atttacaatc ataaaacaga
    15661 taaaagagat tgtttctcag aatgctgata ttaaggtttg gaatctttct ttagggtcca
    15721 atgatgaaat aagagaaaat tttatctctg cagagggagc attattagac gaaattcaat
    15781 ttgagaatga tgtaattttt atcatagctg ggacaaatgc ttcagtaata aatgggaaac
    15841 gcaaaagaat aggtgctcct gctgattcac ttaattctat aatagtaaat tctgttgatt
    15901 ttaataatca atcagtgtca tattcacgag agggtattgt tttatcattc tttgttaaac
    15961 cagatgtgtc atattatgga ggaggaaatg gtgactttat aaatgtttgt gaacctctag
    16021 gattaggtcg tgtagctgga acaagttttg cggcaccttt tattgcaagg aaaatggcct
    16081 atctcattca tattatggga cttagccgag aagaagcgaa ggctttgcta attgatgcag
    16141 caataccctg gaatgataag aaaacattca ctgatttatc tttgatagga aatggtattg
    16201 ttccaataaa aatggatgat attttatcta cacctgatga tgaaattaaa tttattgtgt
    16261 cagatatctc tagggcttat gatacctata attatgattt tccagtacct atttctagtg
    16321 agagttatcc atatgtagct aaagcaacaa tgtgttattt ccctaactgc tcaagaaaac
    16381 aaggggttga ttatacaaat actgagatgc agcttacttt tggtaggtta aagtcagacg
    16441 gtatcaaatc gataaataaa gacaaccagc atgccgaaga taccccagga tatgtgagag
    16501 aaaacgctgc tagaaatata tttaggaaat gggataatgt caagcatatt ggagagtcgt
    16561 ttacttctcg aaagagagct aaagcaattt taaatccatc taatcctcag tgggggatga
    16621 gtattaaaac aatcgaacgt ttgaaaagcg gtgatggaca aggagtacgt tttggtgtag
    16681 tagttacatt aaaagaatta aatggggtta atcgtattga agattttatt cagcaagctg
    16741 aattacgcgg ttggttagtt aatagattgc aagtagaagc tcaagtagac ctctttaata
    16801 gtttaaatga agaaattgaa tttgaatagt ggatatttta tccttatttt agatcttagg
    16861 aacacaagag ggcaaagata tgaatattac ttatatagtt ggaaatggtt tggatttgca
    16921 atatggtttg aaaacaagat atagggattt ctacgaattc caaaataagg tttatataag
    16981 taggacagag aacgaggaaa aatattcaaa tttcatttat gagtctctat tttctgataa
    17041 agtaaatgat tatgaaaatt ggtcagattt tgaattgtca attggtaaat tgacaaaaga
    17101 taacgacctc atctcctcaa gtatagaaat aaaggagaaa tttatagatg attttagtga
    17161 agtagttgat gatttaagag aatatctacg catacaacaa gaaaaaaatc ttgagaaagg
    17221 taatgcaatt gactttataa gcactctaga tgatatgagg acctctctcc ctgtaattaa
    17281 tcaacctgct atcgataaaa aatacaatga gaatccacat caggacgaca ttgtaaatat
    17341 agtaacactt aattatacac atgtaatcga taaattatat aatgggtcag caaaatcatt
    17401 caggaatcaa ttacgagcta atctttataa tttttatatt gagccaccaa ttcatgcaca
    17461 tgggacggtg gatgtctgca cggttttagg ggttagtgat gaaatacaaa tttcaaatag
    17521 tttagaagaa caaaaggaat ccctaataaa aagtttagtt ttaaaaaact atagagaaaa
    17581 tatggatgta aagaatagtg atattataaa aaattctgac atcattattc tctatggggt
    17641 ttctttggga gaaactgata ggtatatctg gagtcagatt gctgaacgat caatcagcgg
    17701 ttctgttcct gtcataattt accactatgt acctcatttt gatccgggga atcccattag
    17761 agcaaaacgc ctatatagaa atgtagaaga taaattcata cagaatagtg gtatagactt
    17821 agagttagag aaaaaattaa gagacaacct tattgtcgtt attggtaaga ctatttttga
    17881 tctaatagag aggtaatttt aaaaaacaaa atggaaacat ggcaagagtt aaaagttaca
    17941 gtgaagcgtg agggagagga gttggtttcc aatctcttga ttgagctggg agcgcaaggt
    18001 gttgcgattg aagacagtat ggactatgtg ggaaatgttg accgctttgg cgagattttc
    18061 ccagaggtgg agcagcaaga agaaatcgta gtgacagcct actaccctga cacggtggat
    18121 gtgacagtgg ttgaggcgga cttgcaggct cgcttagcag aattgacgga ttttatggat
    18181 ttgggagagt taaaaatagg tacgactgtc ttggctgagg aagactgggc agataactgg
    18241 aagaaatact atgagccagc tcgtatcact catgatttga ccatcgttcc ctcttggaca
    18301 gactatgagg cgactgcggg ggaaatgatt atcaagctgg atcctggcat ggcttttggt
    18361 actggaaccc acccaactac caagatgagc ctttttgcct tggaacaggt tcttcgtggt
    18421 ggcgaaacgg tgctagatgt ggggactggt tcaggggttc tctctattgc cagctcgctt
    18481 ctgggggcta aagaaatttt cgcctatgac ctagatgatg tagcagttcg tgttgctcag
    18541 gaaaatattg aacttaaccc tggaatggaa aatatccacg ttgctgctgg agacttgctt
    18601 aagggtgttg agattgaggc agatgtgatt gtagctaata tcttggcgga tattctcatt
    18661 catctgacag acgatgccta tcgtttggtc aaggatgaag gctacctgat catgagtggc
    18721 attatcaagg acaagtggga catggtgcgc gagtcggctg agtcagctgg atttttcctt
    18781 gaaacccaca tggttcaagg ggaatggaat gcctgtgtct ttaagaaaac caaggatatt
    18841 tctggtgtga ttggaggcta gcatgcagca gtattttgta aaaggcagtg ctatctctcc
    18901 tgtcactatc gaggacaagg aaaccagtaa gcatatgttt caggttatgc gcttgaaaga
    18961 agaggatgag gttaccttag tctttgatga tggcatcaag cgcttggcgc gcgtgctgga
    19021 tatggaaaat cgtcagtttg agttggtcca agaattaaat gacaatgtgg aactaccagt
    19081 tcaagtgacc atcgcatctg gatttcccaa gggagacaag ctggagttca tcgctcaaaa
    19141 agtaaccgaa ctgggtgcta gccaaatctg ggcctttcct gcagactggt cagttgccaa
    19201 gtgggatggc aagaaattgg gtaaaaaagt tgaaaaacta gaaaaaattg cccttggagc
    19261 agccgagcaa agcaagcgta atattgtacc aagtattaaa cttttcgaga aaaaagcaga
    19321 ttttctaact cagctggacc agtttgactc tatcatagta gcctatgaag aatcagctaa
    19381 agaaggagaa gccgctgcgc ttctgcaagc agtcactggt cttgaaacag gagccaaact
    19441 gctctttatc tttggtccag aaggcggtct ctcacctgca gaaatcgaaa gttttgaagc
    19501 taagggagcc gttttggtag gcctaggtcc tcgtattttg cgagcagaaa cagcaccgct
    19561 ttacgcctta tcagccctta gtgttttagt agaattagag aaataagagg aagaaaatgg
    19621 aacaaaaaca ccgttcagaa tttccagaga aggaactttg ggatttaaca gctctatacc
    19681 aagaccgtga ggatttcttg cgtgcaatcg agaaagctcg cgaagacatc aaccagttta
    19741 gccgtgatta caagggcaat cttcacactt ttgaggattt cgagaaggcc tttgcggaat
    19801 tggaacagat ctacattcag atgagccata ttggcaacta tgcttttatg cctcagacga
    19861 cggactatag caatgacgaa tttgcaaata ttgctcaagc tgggatggaa tttgaaacag
    19921 atgccagcgt agccttgacc ttctttgacg atgccttggt ggtagcagac gaggaagtct
    19981 tggaccgttt gggtgaattg cctcacttga cggcagctat tcgtcaggcc aaaatcaaaa
    20041 aagcccacta tctaggggct gatgtggaga aggccttgac caatctcggt gaagttttct
    20101 atagtccgca ggacatttat actaagatgc gagctgggga ttttgaaatg gctgactttg
    20161 aagcccatgg caagacctat aaaaacagct ttgtcaccta tgagaatttc taccaaaatc
    20221 acgaggatgc tgaggttcgt gagaaatcct tccgttcctt ctcagaggga cttcgtaagc
    20281 accaaaatac ggctgcagca gcctatctgg ctcaggtcaa gtctgaaaaa ctcttggctg
    20341 atatgaaggg atacgactct gtctttgatt atcttctagc tgaacaagaa gtggaccgtg
    20401 tcatgtttga ccgccagatt gacctcatca tgaaggactt tgcaccagtc gctcagagat
    20461 acctcaagca tgttgccaag gtaaatggtc ttgaaaagat gacctttgca gactggaaat
    20521 tggacttgga cagcgccctc aatcctgaag tgactattga cgatgcctat gatttggtca
    20581 tgaagtcggt agaacctttg gggcaagaat attgtcagga agttgctcgt taccaagaag
    20641 agcgctgggt ggactttgct gctaacagtg gcaaggattc cggtggttat gcggcggacc
    20701 catatcgcgt acacccttat gtactcatga gctggacagg ccgtttgagc gatgtctata
    20761 ccttgattca tgaaatcggg cattctggtc aattcatctt ttcagacaat caccaaagct
    20821 atttcaacgc ccacatgtcg acctattatg ttgaagcacc gtcgaccttc aatgaattgc
    20881 tactcagtga ttacttagag aaccagtcta atgacccacg tcaaaaacgc ttcgctctgg
    20941 ctcatcgctt gacagacacc tacttccata atttcatcac ccacctcttg gaagccgcct
    21001 tccagcgtaa ggtgtataca ttgattgaag aaggagaaac cttcggagca agcaaactca
    21061 acagcattat gaaggaagtt ttgacagatt tttggggcga tgccattgaa atcgacgacg
    21121 atgcagcttt gacttggatg cgccaagctc actactatat gggcttgtat agttacactt
    21181 actctgctgg tcttgtcatc tcgacagctg gttaccttca tcttaaaaac tcagaaactg
    21241 gagctgaaga ctggctcaat ctcctcaaat caggtggtag caagacacca cttgagtcag
    21301 ccatgattat cggtgctgat atttcaacag acaaaccact ccgtgatacc atccaattct
    21361 tgtctgacac agttgaccag attatcgcct acagtgctga gttgggggag taaggggaat
    21421 agaaaaattt tctagaatga tgtttatggg cttgttaagc gtcattctat ttgtcttagt
    21481 tgtagctatt ttcaaaaatg tcgttgaagg tcgtgatgtt aaatttgaac ttactgtaga
    21541 actggtattg atagttattt acgtcatttt atatcagatt gtatttaatt gagaattcaa
    21601 tattgagtca tttaagactg cctttttgaa cagttgctag aaatgtagag gtattgacca
    21661 tgtatcaaga tttactaaga aaaatagcag aagaaaaacc aaattataac caggaagaaa
    21721 tccagtggtt gtttgatcat ttgggaaatc cttctccaga aattcgtgat gacctttcaa
    21781 atcaaggctt gcactatctt tcaaaagaaa aggatacaac aggtttctca agtcagtatg
    21841 gttgggttca cgcttttgca catggagccg atttactgac agaggtggtt tgtcatccag
    21901 actttcctaa aaacagagtt catgaagtat ttgatatact tggccaacta tttaaaagaa
    21961 tgtcgattcg ctttacagat gatgaggatt ggcgtttagc aagagtgatc tatgaaccta
    22021 ttttacaagg gaagttggag caagaacaag tagcttcttg gataaaaact gttgattttc
    22081 cgatagaaga aagggaggat ttttacaaat tttccaactt tagatcctgt ctggtggaag
    22141 tctatgtcca acttgaccag agaaatagtt tacaagatga gttgaaagaa gctatccagt
    22201 cttttcaata ctagagatta gctaatagtt ctatgatttt caaaaaattt ccaatcaatt
    22261 ttcttgaaac cctttcctac ttttgataga ctagtatcta gtttttgaaa aaaggagaaa
    22321 gaaaatgaaa aaatttgttg ctgagttaat cggtacgttc atgcttgtgt tcgttgggac
    22381 aggagctgtt gtttttggaa atggtcttga tggccttggt caccttggaa tcgcctttgc
    22441 ctttggtttg gcaatcgtgg tggcagccta ctcaatcgga actgtttcag gtgctcactt
    22501 gaacccggct gtttcgattg ctatgtttgt aaacaaacgt ttgtcatctt cagaacttgt
    22561 aaactacatc cttggtcagg ttgttggagc tttcatcgct tctggcgctg tcttcttcct
    22621 cttggctaac tcaggtatgt caactgctag tcttggtgaa aatgccttgg caaacggtgt
    22681 cactgtcttt ggtggtttct tgtttgaagt catcgcaact ttcttgtttg tattggttat
    22741 catgactgtg acttcagaaa gcaagggcaa tggcgcgatt gctggtttgg taatcggttt
    22801 gtcattgatg gcgatgattc ttgtcggatt gaagattact ggactttcag taaacccagc
    22861 tcgtagcttg gcaccagctg tcttggtagg cggcgcagcc cttcaacaag tttggatttt
    22921 catccttgca ccaatcgctg gtggagttct tgcagccctt gttgcaaaaa atttccttgg
    22981 aacagaagaa taattgaaac tcaaaaagcc ttgctcctca tcttgaggaa cagggctttt
    23041 tcgtatgata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg ccgtaggtat
    23101 ggttactgac ttcgtcagtt ctatcc
//
LOCUS       DAVKUR010000030        22959 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKUR010000030 DAVKUR010000000
VERSION     DAVKUR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22959
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.030"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..942)
                     /locus_tag="VW749_001323"
     CDS             complement(<1..942)
                     /locus_tag="VW749_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0175356.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEEGPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFL"
     gene            1190..1615
                     /locus_tag="VW749_001324"
     CDS             1190..1615
                     /locus_tag="VW749_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0175357.1"
                     /translation="MELSIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPEL
                     ADAMLAAKITGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            1616..2029
                     /locus_tag="VW749_001325"
     CDS             1616..2029
                     /locus_tag="VW749_001325"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0175358.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            1975..2301
                     /locus_tag="VW749_001326"
     CDS             1975..2301
                     /locus_tag="VW749_001326"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175359.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(2668..2928)
                     /locus_tag="VW749_001327"
                     /pseudo
     CDS             complement(2668..2928)
                     /locus_tag="VW749_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(2931..3431)
                     /locus_tag="VW749_001328"
     CDS             complement(2931..3431)
                     /locus_tag="VW749_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175360.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            3467..3646
                     /locus_tag="VW749_001329"
     CDS             3467..3646
                     /locus_tag="VW749_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175361.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(3624..4592)
                     /locus_tag="VW749_001330"
     CDS             complement(3624..4592)
                     /locus_tag="VW749_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0175362.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(4678..4893)
                     /locus_tag="VW749_001331"
     CDS             complement(4678..4893)
                     /locus_tag="VW749_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0175363.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(4902..5756)
                     /gene="cvfB"
                     /locus_tag="VW749_001332"
     CDS             complement(4902..5756)
                     /gene="cvfB"
                     /locus_tag="VW749_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0175364.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(5816..6373)
                     /gene="frr"
                     /locus_tag="VW749_001333"
     CDS             complement(5816..6373)
                     /gene="frr"
                     /locus_tag="VW749_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0175365.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(6382..7119)
                     /locus_tag="VW749_001334"
     CDS             complement(6382..7119)
                     /locus_tag="VW749_001334"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0175366.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(7203..8537)
                     /gene="trmFO"
                     /locus_tag="VW749_001335"
     CDS             complement(7203..8537)
                     /gene="trmFO"
                     /locus_tag="VW749_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0175367.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(8832..9086)
                     /locus_tag="VW749_001336"
     CDS             complement(8832..9086)
                     /locus_tag="VW749_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0175368.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            9081..9885
                     /locus_tag="VW749_001337"
     CDS             join(9081..9449,9451..9885)
                     /locus_tag="VW749_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0175369.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(9874..10520)
                     /locus_tag="VW749_001338"
                     /pseudo
     CDS             complement(9874..10520)
                     /locus_tag="VW749_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(10629..11147)
                     /locus_tag="VW749_001339"
     CDS             complement(10629..11147)
                     /locus_tag="VW749_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0175370.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(11374..12243)
                     /gene="rsmI"
                     /locus_tag="VW749_001340"
     CDS             complement(11374..12243)
                     /gene="rsmI"
                     /locus_tag="VW749_001340"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0175371.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(12246..12563)
                     /gene="yabA"
                     /locus_tag="VW749_001341"
     CDS             complement(12246..12563)
                     /gene="yabA"
                     /locus_tag="VW749_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0175372.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(12603..13493)
                     /locus_tag="VW749_001342"
     CDS             complement(12603..13493)
                     /locus_tag="VW749_001342"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0175373.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(13490..14128)
                     /locus_tag="VW749_001343"
     CDS             complement(13490..14128)
                     /locus_tag="VW749_001343"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0175374.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(14348..15145)
                     /gene="proC"
                     /locus_tag="VW749_001344"
     CDS             complement(14348..15145)
                     /gene="proC"
                     /locus_tag="VW749_001344"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0175375.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(15149..16411)
                     /locus_tag="VW749_001345"
     CDS             complement(15149..16411)
                     /locus_tag="VW749_001345"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0175376.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(16421..17551)
                     /locus_tag="VW749_001346"
     CDS             complement(16421..17551)
                     /locus_tag="VW749_001346"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0175377.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(17631..19514)
                     /gene="cbpE"
                     /locus_tag="VW749_001347"
                     /gene_synonym="pce"
     CDS             complement(17631..19514)
                     /gene="cbpE"
                     /locus_tag="VW749_001347"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0175378.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(19517..20404)
                     /locus_tag="VW749_001348"
     CDS             complement(19517..20404)
                     /locus_tag="VW749_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0175379.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(20394..20855)
                     /locus_tag="VW749_001349"
     CDS             complement(20394..20855)
                     /locus_tag="VW749_001349"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0175380.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(20852..21760)
                     /locus_tag="VW749_001350"
     CDS             complement(20852..21760)
                     /locus_tag="VW749_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0175381.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            21753..21950
                     /locus_tag="VW749_001351"
                     /pseudo
     CDS             21753..21950
                     /locus_tag="VW749_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(22002..22673)
                     /locus_tag="VW749_001352"
     CDS             complement(22002..22673)
                     /locus_tag="VW749_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175382.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(22727..22948)
                     /locus_tag="VW749_001353"
     CDS             complement(22727..22948)
                     /locus_tag="VW749_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0175383.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
BASE COUNT         6594 a         5286 c         4116 g         6963 t
ORIGIN      
        1 aagaaattca cttggcgact tgtagtccaa gcatttttta gggtagttgt taatccaatt
       61 ttcgataaaa gctacttctt tcggagtcgt tttcttggtt cctttaggta accatctccg
      121 aattaatcga ttatgatttt catttgaacc tctctcccat gaagagtaag catgtgcgta
      181 gtagatatgt tcctcaggaa atacctcaga caatcgtttg aactccgaac cattatctgc
      241 agtaatggac agaatacgat gctcccctaa tagtaacgta agcgcctgat tgacagattc
      301 agcagtttta tttggaatta accttataat ttggtgtctg ctccgccggt cggttaagac
      361 taacaggcaa taatttttta tcttagtcag taggacggta tcaatttcat aatgaccatt
      421 ttccaagcga agattaataa cgtcaggacc ttcttcgata gatttacctg ccggcttaaa
      481 gttcggacta gcttgcttct tgacaccttt cctttttctg ggataaagca tgtcggcctt
      541 cgtcaatcct aaatgaccat tatgaaacca gtagtagatg gttgaaatac caactttcac
      601 ttgcttcttg ttaaccatca tttcaggcga aaatttttgc ttatgatagt gtaagatctt
      661 ctctctgatt tcctttgtta aaattaactt tttcaccgac cgttttcgat tgaattggta
      721 aacagtttgt gcgtaatcgg cagaatagac ctttttgtat agcccttttc tcacttgttg
      781 taaagttgta cctcttttga cttcattatg aatcgtttga ggcgcctttc ctaacaagcc
      841 tgcaatttca cgattggact tattttcatt cttccaccgc tcaatcaagc gacggttatc
      901 tattgtcaaa tgtttccctt ttggggtata atgttcttgc atctctgtgc ctttccttgt
      961 gtttgtggtg aacaacaagt atagcacaga ggtgttttct tataccttaa atcacatttc
     1021 atttgacaac aggaaccctt gaacctgttt tttcagctaa accaaggcta tgattagcct
     1081 tggccaccta gcctaacagt ttcaaacctg ttatcaaatg aaatcatcaa cttactcaaa
     1141 catagtgaaa catctaattc ttgactaagg taaggtggct aacttcatta tagaactttc
     1201 aatcccaaaa gaaattaaaa ataacgaaaa ccgtgtcgcc ctcacacctg caggtgttca
     1261 tagcttagtt agtcgtggtc atcgtgtcct tatcgaaaca aatgctggtc tcggttctgg
     1321 ctttactgat gctgactatc aaaagcaagg agctgagatt gtcgctactg ctggtgaagc
     1381 ttgggcagca gagttggttg tgaaagtaaa agaaccttta agttctgaat acggttactt
     1441 gcgcgacgtt cttcttctct tcacctactt gcacatggcc gctgctccag aattagcaga
     1501 tgctatgtta gcagcaaaaa taacaggaat tgcctatgaa actgttcgtg acaatcaagg
     1561 acaactaccg ctcctcgttc ctatgagtga ggttgcaggt cgtatggctg tttaaatcgg
     1621 agctcacttc cttactaagc aagctggtgg ctctggtgtt ctacctggtg gtgtaccagg
     1681 tgttccaaaa ggaaaagtaa ctatcatcgg tggtggtgtc gtcggtacac atgctgcccg
     1741 catcgccctt ggtcttggtg ctcaagtgac tattttagat attagtgcca agcgtctctc
     1801 agttctagaa gaagtctttg gaagtcaaat tcaaactctt atatctaatt cattcaacat
     1861 tgaagcaagt atgagagatg ctgatgtggt gattggagcc attctcatcc ctggtgcaaa
     1921 agcaccggaa ttggtgacag atgagatggt caaacaaatg cgtccaggct ctgtatcgtt
     1981 gacgttgctg ttgaccaagg tggcgttatc gaaacagctg accgtgtgac aacgcacgat
     2041 gaacccgtct atgaaaaaca cggtgttctc cactatgccg ttgccaatat ccctggtgcg
     2101 gttgctcgca cttcaaccat cgccctaacc aatgtcactc ttccttatat cgaagctttg
     2161 gctggcaaag gattcgcaca agcaatctct gaagatgaag gcttgcgtca aggtgtgacc
     2221 acttatcaag gttacttgac tagcctacca gttgctcaag gacttaatcg tgactacact
     2281 gatatcaatg atttagtata aattttgaaa agaaaagggt gacttcgcaa gtcctaccca
     2341 ctgtgctttg tgtcatcagc tattacatcg ttggtttatt gtactgtata ctttgcaact
     2401 ggagactttc gttccagact caattgtgca taagaaactc taaattgaat aaagtcaaca
     2461 gagtttcgcc caaccacttc gtcttgtaat gacaattata taaaccaaag gaagctgagc
     2521 tctttagtcc cagcttcttt ttatatataa aattttaccc gtgcaaagac agggccttag
     2581 cagacttctt ttttacttcg ttcacccttg ctttttcttt ttaggtttgg gcgttggcag
     2641 ttggttatac atagctaaaa tcaggtctta tagaaacatc ttattatcaa gttcttccac
     2701 tcaaatcatt tctttggcac ctttgtatgg aaactcaaaa aaagattggt caatcttatc
     2761 taagactgct tgcacgggtt taactaaaaa gcgatcatca taaatgccgc caataatctt
     2821 gccgcggaag taaagaatat actcccccat catggaacgg taagtcacat catctaatcc
     2881 tgataattgt tccaaaacaa attccaaata gttcttactt gatgccattt ctaatcttct
     2941 aggctctgtt cagcgataac aaccgtatag agttcttgct taacctcgca tccaattgat
     3001 ttaaagccct gcttttccca aaaatgctga gattgcggat ttcccttaac ataagccaaa
     3061 cgtgcctttc gaaagttctt agcaaaataa gctagtgctt ctgtcacaat atgactacca
     3121 atccctttcc tctgataggc ttgatcaacc ataaacaaac caataaaaac agtctcctca
     3181 tcaggatgtg catagacaaa atctataaca gccacaaggt cagatccatt ccaaaatcca
     3241 acaaaaaact tatcagcctt agctttacct tcaggtagac aaagcatgtc ctcttttaca
     3301 gttgcaaaat ttggctctgg tggacaatgc tgaaaataca gaggattact ttcatataaa
     3361 gataaaatac ttggaatatc cttttcagtt agtatcctac aactgtaata cttagatagt
     3421 tggtcaatca tcttttcaaa ttcctacttt cttgtgccct gtgattatga cacaggaaga
     3481 tgcactgatc gtcatcagcc acataaaagt tctttccatc gtgcctaatc gttgtctcaa
     3541 acctttggat aaaaccttta gcctatacaa ctggattttc ctctctcaaa agtatattct
     3601 tttgcaggca aacttcctca aaatcagtcg tgtgcaactt cagtagaata ttcataggct
     3661 cggataatct gagcgacaac tggatggcga accacatcct tggctgaaaa atgaacaaag
     3721 tcaatctgat ggatgttctt gagtttctct tgagcatcaa tcaaaccgga cttgacatta
     3781 cgtggcaggt caatctgact aatatctcca ttgacaatca tcttagaatg aaaacctaaa
     3841 cgagtcaaga acatcttcat ctgcatgatg gtcgtatttt gcgcctcatc gagaatgaca
     3901 aaggcatcat ccaaggtccg tccacgcata taggcaaggg gcgcaatctc gataatttca
     3961 cgctccatga gtcgagttgt ttggtctttc cccagaatct gatacaaggc atcgtaaaca
     4021 ggacgaaggt aaggatccac cttctcctta agatcacccg gaagaaatcc aagactctct
     4081 cccgcttcca ccgctggacg agttaggata attcgcttga cttgcccacg tttaagggca
     4141 gtcactgcca aggtcactgc aaggaaggtc ttccctgtac ctgctggccc aattccaaag
     4201 gtcacatcat gctgtttgac actgtccaca taaagctttt gccctagggt tttgacacgg
     4261 ataggtttcc cagtattatc tttgataatt tcttcttcgt aaagggcgac aaacttgtca
     4321 atttcatcat ttttgaccat gctaatcgca gtgactacat ctggcgtacc aacggtcatc
     4381 ccacgattta ccaagaccat caaagcctga ataacttgac gggcttcctc acaggcagac
     4441 tcttctccca aaacctggac aatctccgta cgagcatgaa tcacaacatc aagctcttct
     4501 tccatcaaac gaagatggcg ttcattggaa ccaaaaagat gaaacaggtc atctggatga
     4561 ctcagttgaa tgtctattga atgttccttc aaataaagaa cctctctaat ccttttattt
     4621 ctttttatta tagcagaggg atggagaaat tactagccca aacccaatga ataaatgcta
     4681 gtgttctaga tattcctgcc aaatgctgtc aaaatctcct aggttaaaag agaaactggc
     4741 atgctcctcc aaaaagcgac tgacctcatc aaaatcatct gtatgttttg gaaaagctgc
     4801 ctcttcaaaa gcgaggtctg ccaaaattgc tttgggactg ttacttttag gattgcgctc
     4861 ggtcatgagc caagtgtaaa atgattttct cataagcctc cctaaatcaa ctctgtccca
     4921 aactggtcct gcttgatttt accagccttc ataagaccac ctaaagcttt cttgaactga
     4981 cctttagaaa tgccaaaggt tgccttgatg tcgtctggag atgacttatc atttaaggtc
     5041 atgaaaccgc cattactttc caaataagtc aaaatcatct gagcatcgtt ttccaacatt
     5101 tcaaaggagc gtggtttgag ggagaggttc agagtgcggt ccacttcacg gaaaccaata
     5161 acgcgcgcat ctaatacttg ccccaaacgt ggctctgcgt aacgctcgct aggatgaata
     5221 aaaccaagca tattattttc tggtaggtaa acaaaagttc ctgacagctt gagacggtaa
     5281 acaatggctg gccagttttg gttctgcatg ttgttgtagg caggacgagc aagacgttgg
     5341 aagtcttctt gataagccaa gaggccccag atacggtctt tcttatccac ttcaagacgg
     5401 atgtagagtt ggtcgccctt cttaggccag agttccttga gctcagggag aatatcgagt
     5461 gacacaacga tttccttgtc aggaaggcct gtatctacaa agacacccaa gtccttacga
     5521 acctctgtga cacatcccca accaaattgg tcctgagtgg cagtcacttc taaggttgtc
     5581 aggcggagtt tttgcttcat atccgtgtat gcaaaacctt tgaccgtatc ccctactgta
     5641 tgttggccct cttccttagc aagagcatag gtttgaccat ccttttgcac aaagtaaaaa
     5701 cggtcatttt catcgatgat cagtccaacg ataaaacttg caagatttgt attcatattt
     5761 ccttctttcg aataaaactc agccagcaat gccaactgag tttttctgtt tatttttaga
     5821 cttccaaaag ttctttctct ttgttagcag tcatgtcgtc gatgtgttta acagcatcgt
     5881 ctgttacttt ttgaatatct ttttcaagag tcttcaattc gtcttcagtg atttcttttg
     5941 ctttttcttg tttcttagct tcgtccatag catcgcgacg gatattgcgg acagccactt
     6001 tagcattttc gccgaccttc ttcacttctt tagcaaggtc acgacgagtt tcttctgtaa
     6061 gagctgggat aaccaagcga atcacagaac cgtcattagc cggtgtgata ccaagatcag
     6121 aagcgttcaa ggcacgttcg atgtctttca atgaagactt gtcaaatggt gttaccaaca
     6181 aaacacgcgc ttctggaatc gtaattgaag cgatttggtt aagaggagtt tcgactccat
     6241 agtattctac atgtacacgg tcaagcaagc ttgcattggc acgaccagca cggataccac
     6301 caaattcacg agcaagtgat tggtgagatt gggtcattct ctctttagct ttttcaataa
     6361 ttacgttagc catattcttt cttattcctt ttcttcgata ttatttgaaa ctgttgttcc
     6421 gatattttca ccaaatacga cacgtttgat gttgcctgat tggttcatgt tgaagacaac
     6481 caagtcaatg tcgttgtcca ttgagagggt tgaggctgtt gagtccatga tacgaagacc
     6541 tttgttgata acatcacggt gggtcaattc ttcaaactta acggctgtct tgtccttctt
     6601 aggatcggca ttgtacacac catcgacgcc atttttagcc atgaggatgg catctgcttc
     6661 gatttcagct gcacgaaggg ccgctgttgt atctgtcgag aagtatggtg aaccaattcc
     6721 agcaccaaag ataacgatac ggcctttttc aaggtgacga agggcacgtc cacggacata
     6781 aggctctgcc acttgttgca tagcaatagc tgtttgtaca cgcgtatcaa ccccaacttg
     6841 ttgcaatgaa tctgccatca caagagcatt cataacagtc ccaagcattc cagtgtaatc
     6901 tgcctgaaca cggtccatac ctgcttctgc tgcaggttct ccacgccaaa gatttcctcc
     6961 accaataaca agggcaattt cgatacctaa gctatgaact tcttgaatct cttttgcgat
     7021 tgtttgaact gtttggatat caatccctac gccacgttca ccggcaaggg cttcacctga
     7081 taacttgatt aaaatacgtt tatacttggg attcgccatt ttcactctcc ttctttcatc
     7141 ctacctattt tatcacaatt tctaagattt ttatagtatc atgagcaatt ctttcaaaaa
     7201 aattagacag tcaaaaattc ctctaagtcg gcaagggcac gctctgcaat tttttcataa
     7261 cgagccttct tatcacggat acgctcgcct tccaactcct tgatgatccc aaaattgaca
     7321 ttcattggtt ggaaatgttt gctgtcggca tgggtaatgt aatgagctaa gcttccaatc
     7381 gctgtcgtct cggggaaaat aacctcgctt tcttccttga agagacgagc tgcgttaatt
     7441 cccgcaacta agcccgaagc cgccgactca acatagcctt ccacccccgt catctgacca
     7501 gcaaagaaga gatttggttg tttcttggaa cggtaagtct gctcaagaag atttggtgaa
     7561 tccatgtaag aattgcgatg catgacacca taacggacaa actccgcatt ttcaagaccc
     7621 ggaatcattt ggaagacacg cttttgttct ccccatttga ggtgggtctg gaaaccaaca
     7681 atattgtaga ggctaccagc tgcattatcc tgacgaagtt gcacaaccgc ataaggtgtt
     7741 ttaaattctc catcacgagg tcctgtgtag tcgtccggat actcaagacc gactggcttc
     7801 atagggccat aaagcatagt tttaatgcca cgtttggcca taacttcgat tggcatacat
     7861 ccttcaaagt acttttcttt ttcaaaagaa ttgagcggtg cttcttccgc attgaccaag
     7921 gcttcatgga aatccataaa ctcttgcttg gtcattggag cattgagata ggctgcttct
     7981 cccttatcat aacgagattt gagatagacc ttactcatat cgatagtgtt gacatcgata
     8041 ataggcgctg ctgcatcgta gaaatagaag ccatcgccat tattaagggc atgaatcttt
     8101 tcagccaggg catcgctagt caagggacca gtcgccacaa ctgtaataac atctgttggc
     8161 aattctgtaa tttcatcacg caccacttca atcaaggggt ggttgaccac tttttcggtc
     8221 accatttgag agaaaccatc acgatccacc gcaagggctc caccggcagg aacacgtgta
     8281 gcctcagcag attccaagat aacagaaccc aagcgacgca tttcttcctt gagaagacca
     8341 actgcatttg tcaaagcatc cccacgcaaa gaattggaac aaaccaactc agcaaaattg
     8401 tctgttttgt gctgaggagt cgacttgaca ccacgcattt cataaagttt aactggaata
     8461 ccacgctctg cgatttggta ggctgcttca gaacctgcca aaccagcacc gataacattg
     8521 atataagatt gagacacgac actaatacct ctttgggagt gtgaagttaa gattcacatt
     8581 gaaaaagcca atcagactta cgagatttcg agtttcttgg ctcaggctga aaaagtcccc
     8641 cagactttcc tcgctctcga atttcttggc tcaagctgaa aaagtccccc ggactttttc
     8701 actcccacaa atctttctat ttttttcttc tactagtata acaaaaaaag ggaagaaggc
     8761 aaacttccct gtttagtcat tttcttgatg taaagagata gagagtattc cagttaagaa
     8821 tcaattatat gctactctat aaaatctttt ccacataacg gatcgatagg gactgttatt
     8881 ctatctcttg ctataaccgt attatctaaa acagcataac attcaacata gtgatctcct
     8941 ttaaactgtg aatcttcgtg atattttatt ttacctgaaa aaatagcacc acgctcacaa
     9001 tttcttctaa tagcctcagc ttcaatattt cttactttcc aatagacttc ctgcgaaaca
     9061 aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact gatgcacgat
     9121 ttaagcgtct tgttggtgtt cagcgcacga cttttgaaga gatattagct gtattaaaaa
     9181 cagcttatca acttaaacac gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc
     9241 ttcttatggc cactcttcaa tatgtgcgag aatatcgaac ttatgaacaa attgcggctg
     9301 attttggtat tcacgaaagc aacttaatcc gtcggagcca atgggttgaa gtaactcttg
     9361 ttcaaagtgg tgttacgatt tcaagaactc ctctcagttc tgaggacacg gtaatgattg
     9421 atgcgacgga agtaaaaatc aatcgcccta aaaaaacaat tagcgaatca ttctggtaaa
     9481 aagaaatttc acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct
     9541 ttggatatcg ctgtgaacta ttgtcgtgat atgaagttgt tcaaaatgag tcgcagaaat
     9601 atcggacaag ctggtaaaat cttgtctgac agtggttatc aagggctcat gaagatatat
     9661 cctcaagtac aaactccacg taaatccagc aaactcaagc cgctaacagc tgaagataaa
     9721 gcctgtaacc atgcgctatc caaggagaga agcaagattg agaacatctt tgccaaagta
     9781 aaaacgttta aaatgttttc aacaatctat cgaaatcatc gtaaacgctt cggattacga
     9841 atgaatttga ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct
     9901 aatgtaattc tcaagctgtg agttcattat gatttgtaaa tccgatatat cttcagcagc
     9961 taaaaacaca ttttgaaatg ttccaagtcc gttttcacca aaactatatt ctctcttact
    10021 atacttactc ttattattct ctatatagtt agagtcaagg ttcttaacct cttgaagttc
    10081 attttcttta cttctgaggt taaaatcttt tacttctgaa gttaagtttt ttgacttctg
    10141 taagtcattt tcttttacct gaaatatact cataaagtct ttaacataaa tgatgttcgg
    10201 cttaccaagt ccaagcctta ctctttcgat cagtcctatt ccttttttac atcaagctca
    10261 tctaatgttt ttatggcagt tggctttgag atatttcttc ttttcataat ttcttcgaca
    10321 gtaaaataga taaatactct gccttccttg tctatccagt tattcttaaa tgacattcct
    10381 gtctgtttaa gaagtatgga ataaaggata attgcttctg ctgataagcc ccgaaattct
    10441 tctctatcaa ctaatatctc cggtactttt aagaagttaa atctttccgc ttctctgtta
    10501 taaaaatatt caaagtccat gcaagatcac ctcccttctt aaaaatttgc aaagaaaaag
    10561 acgatagttt ttcttctatc gcctttggta accattttta tgaaattttt taaagttaaa
    10621 aatataattt ataatactat cttcttccat tttctgattt tagttctgaa agttccaaaa
    10681 ggtgcaaccg tatttacatg aataaactta tacacttccc aagtcgctgt tttagtcgct
    10741 tcatcagccc actttctcat atgcggttca aataattctt cctcactcaa cgaatcaatc
    10801 attgcagaga tagaattaat attttcattt aattttgctt tcaactcttg cagagataaa
    10861 tgagcgtagg tatctgtgaa ccactgatat aattcaccaa gttgattcca tttaaattta
    10921 tccgatggtg tttttacttg aagccccttt ctttcatctt cttcccattt aagaaccaag
    10981 ttggtccaac caacctgata agcaaggttt tctgctggag ttctgtcaac ttcatcagct
    11041 ctcttatctt ttaaattttc tggaatatta tcaaattcta aaatatattt ctcaaatgtt
    11101 ttctctatct cagcttttag ttcttcttta ttttcgtatg ttcgcaaaaa atcaccttct
    11161 ttctgattta tcaatccttt gatttaaaat gaccttattt ttctatttat accttctaag
    11221 aacgctataa ctgctgctcc aaccatcggt attccgtatg ggcttaataa aaaacttaat
    11281 accaaagctt ctataccaag tgatacatct ttatattatc atcactaatt aagttaaaca
    11341 gaaacagaca gaattattac atcctgtctc cctttattgt ttttcttccc agtcgtggta
    11401 ggcagcgtag agctgacttt tattccactg gtaaatctta gcgacttcct tgatagcttg
    11461 gtttttcttc acaccttgct ggatgcgggt ttgaatttct acgaacaagt cttcctcgtc
    11521 cttttcctcc acaccctgac tggcaccctc aacaatgaga agacattcgc ccttgagtgg
    11581 cgtttcagca atgctttcta ataactcaga gatagtacct cgttggtatt cttcatagat
    11641 tttggtcaat tccctgacca agacaacgga gcggtcaccg tagacttcta acatattttc
    11701 caacgtgtct gctacacgat gaggtgattc ataaaaaatc tgtgtttcag gataatcttt
    11761 tttcaagcca aaaaattgct tctgctgacc tgattttctc ggtaaaaaac cgtaaaagat
    11821 atgtggctgt ggcgctaaac cactggcaat caaggcagaa attcctgcag aggcacctgg
    11881 aactgtcaca actgcaattt cttcctcaat agctgcctta actaaatcat gaccagggtc
    11941 tgaaatgcta ggcaaaccgg catcagagac ctgagcaata ctttgccctg ctttcaagaa
    12001 accaatcaaa tcaggaattt tttccttggc attgtgctca tgaaaactga tctgcttggt
    12061 ggaaatgtca aaatgcttga gcaaaagccc tgtattgcgc gtatcctcag cagcaatcca
    12121 gtccacttct ttcaaggtct ggatagcacg aaaagtcata tcatctagat tgccaatcgg
    12181 cgttgccact agatacagct tgccataggg agactgcccc ttaaaacttt tttgaatttg
    12241 catgcttact ccctgtataa caactcatca cagaacatac attcttcgtc ctgctctcga
    12301 cgttgtccat aaaaatcatt acatacgtga aatccatcac ggtaaatacg acggacactt
    12361 tcgcgaacat gcttggcctt gacgggagcg tctgcttcca cctcacccaa gcgttctcgc
    12421 aacttactat tttccaagcg aagagctgta ttttcttcta ccaagctctt gagatttttc
    12481 ttgatggctt ccacatcggc taaggttacc aataattgtt gggaaaaatc atccagcgcg
    12541 tcaaataatt cttttttgtc cataaaacag ccctttcctt tctttatcat tcatttttga
    12601 gtttatattt ctttcaagac cagatattcc atggcatttt gaaagctgac attagcttgc
    12661 cacatttttc tagcttctag taaatcttgt agaatcactc ttactcttac ctgcaagagg
    12721 tcctgcccac agagaacttc aagaatccgt aaaacctgat cctgtttttc cttatcatct
    12781 gccaagttgg ctaatttggc aacctgtaga taactttctt ttttcttagc tactaaccaa
    12841 gtcagcaggc gttcactttc atcgaccaag gtccaaaaac ttgcctgatt agccaacttt
    12901 tctgcttcag ctcgcgattg actaaactta gctaaaagag tcgctttttt cttaacaagt
    12961 cccatttgtt ctaagagtaa gataagtttt tcttcttgct ttttaaagtg gaagatctga
    13021 gtccgacttc ggattgtcgg taacatcttt tcctcatcgc tagtcaagaa gaaaatataa
    13081 acttcactct ggggttcttc gatgaccttg agcagagaat tggctgcgtt gggatgcatt
    13141 ttatccgctt gctcgataat aaagacctgt tgctggcttt caatccctgc ttgagaaaac
    13201 tgtcccacca attcccgaat gcgttctgtc ttgatgacct gattgactgg cttaatcaag
    13261 gtgacatctg gaaactcttc ctgttcaatc agcttgcaac ttcggcattt ctcacatggt
    13321 aagacgccaa ctttatccgt acaaaagagg ctcttagcta aaaattgcgc catttccaag
    13381 cttccaaaga aacctgaaaa gagataggcg tgattgagct ggtcttgttc taagatacgg
    13441 acaaaacggt caaactgagc tggttgccaa gcctttagtt gatcttgttt catttggcca
    13501 agtccattcc gtcaaacaag acagccttgg tagtttccac aacttgctcc aaagggagac
    13561 tagcatcaat cttgacaatg cgatttcctt ctttttccag gagagaaagg tagccttgac
    13621 ggactttctt gtgcaattcc aaaccttcca agtccagacg attgacctcg cggtcactat
    13681 tcgcagcaat gcgagccagc ccttcttcca cctcgatgtc aaaatagagt gtcaaatcgg
    13741 gtttgaggcc atctgtcgca aactgattga gccagtcaat ggcttcaata tctaagccac
    13801 gaccaaatcc ctgataggca acagaactat cgataaaacg atccatgatg accaacttgc
    13861 cagcttcaag ggctggaaga actttttcca ccaaatgctg tctgcgactg gcaatataga
    13921 gaagtagctc tgttttagca tccatctgag tatgacttgg atccaaaatc acttcccgaa
    13981 tcttctcccc aatcaagact ccgccaggtt cacgggtcgt cagcaccttt actccttttt
    14041 cctctaaaat tggtagcaga gcctctaaaa cactggtctt gcctgctccc tctggtccct
    14101 caagagagac taaaaatcct tttgacatgt ctaactcatt tcttttttac tacttctatt
    14161 ctatcaaaaa aataggggtt tgtgacaatc tttttgtctt ctcatttcat actcaatgaa
    14221 aatcaaagag caaactagga agctagccgc aggctgtact tgagtacggc aaggtgaagc
    14281 tgacgcagtt tgaatttgat tttcgaagag tatcaaccac cataaaagag gcagataaaa
    14341 ctacctctta tttacctagt tcttgtgttc gtttgtaggc ttgatgaact gcatccatga
    14401 ctgttcctcg gaaagcatgc gcttctaggc ttgctacacc agcgatagtc gaaccgcctg
    14461 ggctacagac ttggtctttc aatactccag gatgttgctg actttcaagg accaattgcc
    14521 cagctcctac cacagtttgt gctgccattt tcaatgctat ttctcgtggt aatcctgtct
    14581 gaacacctgc atctgccaag gcctcgataa aaagatagac aaaggctggt ccacaacctg
    14641 caagacctgt cgctgcatcg attaaacttt ctcctagttc aaccaagaga ccagccttgg
    14701 ctaaaagctg ataaaagagc tcactgtcct cagccctgca attaggagac aaggcataac
    14761 taatcactcc ttgcccgata gaagcagggg tattaggcat catacgaata attcggtgtt
    14821 gacttgggat aagacttgct agtttttcta aggtcaatcc agctgccatc gaaatcaaaa
    14881 gaagactttc tcttttttca aggatggtct ggtattgaga aagcagttca gaaaactgag
    14941 caggcttaac tcctagaaaa atcacatctg cttctgcaaa catttcttca ttgctggaag
    15001 cctgaccacc aaagtctgca atgaaagcat ctaccttagc ttgactacga ttggcaagga
    15061 gaatctcatc tgacgtccta gtctgcaaga cagattttgc caagctagca cccatattcc
    15121 ccaaaccgat aaatccaatc ttcatctctt actcccttat ctgcccatca ccggcaacca
    15181 catacttgta gctggtcaac tctttcaagc ccatgggacc acgcgcgtgc aatttctgag
    15241 tagaaatccc catttcacaa ccaagaccaa attgtcctcc atctgtgaaa cgagttgagg
    15301 cattaacata caccgctgca gagtccactt gatctgtaaa gtatgctgca gcttcagcat
    15361 tttccgtcac aatagcatcc gaatgatggg tgctgtggga ttcaatgtgc gcaaccgctt
    15421 cttctaaact gctcacaacc ttaacagcaa ggacatagtc taaaaactcg gtgtcaaagt
    15481 cttgggtctc agctgcttga cctgaaacaa actggcttgc tttgctatcc aagcggaatt
    15541 gaattggttc cagtccagct tccttacgct ctgcaaccag catttgatcc aagcgaggaa
    15601 ggatgcttgc tgccttgttt tcatgaacca gcagaacctc catggcatta caaacagaag
    15661 gacgactggt tttagcattg ttgatgatag acagcgcctt gtcttcgtct gcatccttat
    15721 ccacatagac atggacaatc ccagtccctg tctcgataac aggtacaatc gcattctcaa
    15781 ccactgcatt gatcaagcca gctcctccac gaggaatgag aaggtctaga tagcccttgg
    15841 ccttcatcat agcataacta ctttcacggc tagtatcctc caccagttga atcacatttg
    15901 gatgaatagt agtcgtctcc aagcccttct tcaaggctgt gacaatggca tgggttgttt
    15961 gataggcatc cttaccacta cgaagaacaa ccgcatttcc actcttaaga gtcaaagcag
    16021 ccgcatcaga cgtcacattt ggacggcttt catagataat accgatgaca cctatagcta
    16081 cacgtttttt tgtgataacc aaaccatttt caagctgact tgtttctaaa acttcaccga
    16141 ttggatctgg taaggcaacc acttcacgaa ttcctcttgc catcgcttct atacgatctg
    16201 catccaaata aagacgatcc aacatcacat ctgagatttt ccccttagcc gctgccatat
    16261 cgagggcatt agccgctaaa atttcctcag tagcagccac taagtgatca gccatggcta
    16321 gcaaggcttg gtttttcact tcttcactag ctgtgttaat cgatttttta acagcctgta
    16381 cctgttcaaa ttgttcttgt ctactcacca tagtttacct ctaaaattct gtaaaaagta
    16441 gttggatttc aggagtaatg gaaatccagt cgtcacggta aatcaagaca cccttggctt
    16501 tttgagaacg caacatatcc tccaaagcag atgctccaaa ttgcacgcgt ccttttccaa
    16561 gtgattttcc actttccttg tcaaatactg tcacgatatc accgtaagaa aaggctcctt
    16621 ctgcttcaac gataccagat aagagaagac tctttccatg ttgagagaga gcttccgcag
    16681 cccctttatc aacccaaata gaaccttgac tctgagcata gaaggcaagc cattgtttct
    16741 gggtacgaag ccccttctct tgagcaacaa agtaagaacc atcctcggtc tcctctgccg
    16801 cctcaatcat ggaatctgat ttcaaggatg agcagatata aacaggaact cctgattccg
    16861 tcgcgatagt tgcagccttg attttggtta acataccccc agttccgttt gacgaaccag
    16921 ctccaccagc catatcaata atctcacgat tgatggtctc gattctctcc aagcgtttgg
    16981 ctcttggatc tgaattagga tttccagtat agagaccgtc cacatctgtc aagaaaacta
    17041 aaaggtctgc ttggaccatc gccgctactt gagcacttag agtgtcattg tccccaacct
    17101 tgagctcatc aataacgaca ctatcattct cattgatgat aggaattgcc ccacggttga
    17161 gcaaaaccga caaagcctga tgggcatttt tataacgacg cttatccaca aagtcatctt
    17221 gggtcagcaa gatttgtgca gaaacgattt gacgcaagag aagattggtc gtatattctt
    17281 ccaacaaaag tccctgccct accgctgctg aagcctgttt atcagcaatt ttagtcggac
    17341 gctttttaaa tcctaaggct ccaaaaccag ccgcaatggc acctgaagac accaaaatca
    17401 actcatgacc agcctcgtgc agcatagcca actgctgggt aatatccttt accttactac
    17461 gtgataaact tccatcctca tttgtcagag aagaagtacc caccttaaag acaatccgtt
    17521 tgtatttcat agtctcactc cgattattca tatttatcca ttataacatg aataacagga
    17581 aatagaaaag agttgatagg aaaaagaagg ccctaaaacc ttcttttcta ctactgttct
    17641 gattccgatt tgtttacact cgtttcagag ctttgtgaag ttgaggatgt caaatcttga
    17701 ctagttgaaa aatttgtaac actttcatgt tgactcgttt ctttattttc aagatccttt
    17761 ttcactactt ctttggattc ttttatttct gaatgacttg tagttttaat tgtagcagat
    17821 ttctcgatcg aaacatccac taaccaggca ccacttgaat ccacagtata accttctggt
    17881 gtcttaccgt tcacaagtaa ttgaccattt tctttcaaga agtaccattt atccttgtcc
    17941 ttgatccaac ccacagctcg tgaaccgtct gtcttgtaga aataccaatc atttgccttt
    18001 ttatgccagc cttgcttcat agctcctgaa tcttccagat aataatgttg accagcaact
    18061 tctatctcac ctgtcttcat gacaccagta gaatccatat agtaccaggt ttctttatct
    18121 tttacccagc ccattttcat ttcccctgat ggagcaaagt aataccattg ccccatatat
    18181 tgaagccatc ctgtcttcat agaaccatca acatccaaat aataccactg ctctttatct
    18241 tgaatccaac caatttccat ctggttttct ttgttaaaat aataccagat tccagcgatt
    18301 ttcttccaat ttttagcaga agcaccagag tctgtcaaat agaaccaatg attgttccat
    18361 tttttccatt gattctgtaa caagataccc gtttggttaa agtaatacca ttcaccttcg
    18421 atttcattcc aaccgacagc atactctcct gtagaatcag gcgcttgata ccaccagttc
    18481 ccatatgcac tcttatgcca accagcttga aaacttggaa tcggcttgta ggatgttgaa
    18541 atattgacaa aaccgtcttt tcgaatatca aaaactgttg catcatagtc tttgctggct
    18601 gcgttgattc tctcaattcc tcgttctttg agccaattaa catactcact atcaacacca
    18661 tttttccaag gtagactatc cgaagtttga acaatcaaac tcggactcaa atttttaatg
    18721 aaatccttgg tatttgattt gttggtatca tggtgatgat taaacttcat caaatcaact
    18781 tttccaatga gaggaccata cttgtcttct gctccatgaa cattatctaa atcgccccca
    18841 aggtaaattt tcttgccatt gactttcacc acgctaatca aggaattgga attgtcatcc
    18901 caaattttct ttaattcacc cgatgaatca gtttcatttt cataattata gagctgaata
    18961 tccatgtccc caaactgaaa atgagcatcc ccttgtgtga tattttgaat aactgaaaca
    19021 cctttttctg cagcagtctg taaaacctta tcatagccat acagattatc ccatagacgt
    19081 tcagaattag taatacgact atcactatat ttcttaagat agactcggtc aactggatag
    19141 gtagacagta attcatcaac atttccaata tgatcactgt gggtatgggt caccaaaata
    19201 aaatcaagtt tttggacacc caattccttc aaacgacgaa agacacggtc tgttagaaca
    19261 tgcttataag acgtttcaat tccttctctc catggatagc gagaatcact tccatctggg
    19321 aaatcataat cttctcctgt atccaccatg gcaaaatgtc cattgctttc aagaataatc
    19381 gcatcactgc caccttcttg aacattgata aagtggattt tatttcctga actttcttga
    19441 gcctgaacat tcccatacca tgacaaacct aaaaaagcgc ctacaagtgc taaactagtt
    19501 aatttctttt tcattcttac tttctcaatc tctccaaggt ttccttaaaa atctctggga
    19561 tatctgcttt aaattccaag gtcttacctg ttctcggatg agtaaaacct aaagtcttgg
    19621 catgaagaaa ttgtccatgt cctttcaaag tcttgcgagg accatagacc tcatcaccag
    19681 cgactggatg gccgatataa gccatgtgga cacggatttg atgagtgcgc cctgtctcca
    19741 gttgcaactc tactaagcta taatcgccaa agcgttccaa gacgtgaaaa cgcgtcactg
    19801 caggcttccc tttagcagtt acagcctgtt tcttacggtc tttttcactc cggccaatcg
    19861 gcgcttcaat tacaccacga tcattaggta gatttccatg aacaatcgcc caatatttgc
    19921 ggagagactt tttatccttg agttcttggg caagtgctag atgcgcatca tcgtttttag
    19981 caatcatgag aagacctgac gtatccttat caatacggtg aacaatccct ggacgcagaa
    20041 ccccattgat acccgacaag tccttaatat gatacatgag ggcatttact agggttccac
    20101 tggtatgacc agcactcggg tgcacaacca ttccctgagg tttgttaacg acagccacat
    20161 cctcatcttg gtagactatt tctagcggaa gatcctcagc cacatactct aatacctctg
    20221 gttctggcac atggtaagtg acgacatcac cctcttggac tgtgtattta gctttcttga
    20281 cttgaccatt gaccaagacc tggcctgatt taatttgttc attcgcgaga ctacgtgata
    20341 attctgacaa atctgacaaa gccttatcca aacgcagacc accagtttca attttaattt
    20401 ccatttattt cctcttttag cattgcaatc aataaaataa tcactccaac cgtcagatag
    20461 ctatctgcca cattgaaaat tgcaaagttg ataaagtcaa ggtggaacat atccacaaca
    20521 aagccctgac tgaccctgtc aataaagttt ccaagaccac ccgcgattat tagagtcaaa
    20581 cccaagacca tccagaatga gtcctccatg tgtttatgta aataccaaat ggcacctatc
    20641 acgacaacca gagtaatgac agcgaataac aactgctgat cttgtaagat agaaaaggct
    20701 gcacctcgat tttgcaggta ggtcaagcta acgaaattgg ggatccagga gcgcacttca
    20761 cccagtggaa tctgctggac gatgtaggat ttgaccaact gatccagccc aatcaaaagc
    20821 agtacaatga ctgccactat tgctcttttt ttcatgattt cctcttttga tcaaaatatt
    20881 cttgcatgac ttctacgaag agagtcccag cttgactaag ctccacttct tcacgtttaa
    20941 catagaccat gcggttatct aggttatcct tgagacgaat aactgtaatg ccattaacac
    21001 tgtcactatc taaaaatcca gaacctgtcg cataggcgtc cgtccgctcc aaaataccat
    21061 tcaaggtggc acggtctgtc acattaaaca tctgtgagct agcgctggta tcaacaaagt
    21121 tctctgaata ataaaggtac tcgtctttct cttgagtgaa acgaaccgtt ggtaaatccg
    21181 ctaaatcctc catgactaat tcctctttct gggctaaagg atgaccctca cagagataaa
    21241 tatgggtatg gaaaggaatc aattcgatga cctccagacc taacttttca acccgttgca
    21301 taatcccctt tttattttga ttgttgaggt agataatccc aatctcacta tgcccttgcg
    21361 ccacttcatc taatatttga acagtagttg attcaaaaat acggaagttc ttatagtcag
    21421 gatagcgctc tgaaaaggcc gtaatagttg gtggtaagaa gtcatagtgc tggctagcaa
    21481 cggaaaattc atctttttct tcttcaggat tggcatactg attttgaaaa atatcaaatc
    21541 ctttaaccaa ttcttgcgct ttttcataaa attccatccc acgacgggtc aagaaagtcc
    21601 ctgagctggt ccgacggaaa atcttaaaac ccaactcttt ttccaaatcc cgaacagaaa
    21661 tagacagact cggctgacta acatacatct tttcagcagc ttcacgaaaa gtaccactat
    21721 tggcaatagc cacaacatag cgtaattgtt gaatgttcat cttctacccc taacttcttt
    21781 atcttttcat tataccatat tttagaagtt ttccaaaaag gaaaaaagaa catcctattc
    21841 ttcttaacta tcttcactat ctgcctttct cacgccaatc ttattttcaa aatcaattca
    21901 aaaaaataag tggctacaca ccacttcagt atcggaaaga aaaacgttga ctatttgtga
    21961 aaaaagaaaa tgccggaaaa ttccgacatt tttttagtaa gctaacttcc tgaaaatagg
    22021 agtaaccaaa catcccagaa ggcagtgata ttgatgagaa tatgaactag tattggatag
    22081 tagagatttt tagtcatgcg atacaataga gctaaaatca gacctccact agcataaatg
    22141 aaaaaagcaa gaggagttaa agcaaaattg atatgaatat aaccgaaaat aatagcagaa
    22201 agcaaaacat ctccgtacca aggtgagttt ttgaaaaagg ttgtcataag cacacctcga
    22261 taaatcaatt cctcagcaat aggggcgatg aagcaaacga tgagcaagaa ataagggaac
    22321 tcctgtctcc ccatcatttc tatcgtttca ttcaaagaaa tctgatttga agacagggat
    22381 atgaaatacg aaaagaggaa gtcagacata tatgaaatga tgtagcccag taaaaggtag
    22441 atgaagtacc tcagctgcca cttgaaatga aaaattttct ttcctgcaaa aaccagtaga
    22501 tagatgaccg ctaagaaaag aactccgctc tccatcaaaa gcagaatctg aaaaaattca
    22561 cgacttgctg gtagataggg ctttgcgagg tgattgaaaa ctctccaaaa ccaagttgat
    22621 ttgtaaaaaa ttaaggacaa tgctagtaaa atttgaatag cccgtttttt catattaaat
    22681 tctctgcttt ctccccttgt ttcttcatat tactaataaa ttttacttaa aatctcgcag
    22741 cacttccttt gcaaagatga ttgcctcctc caatatatcc taaatcatag gtgcctctgg
    22801 gacaaaatcc atgaaccggc agagttaata ctggttctat ttcccaatcg tacctaccat
    22861 taggattttt accatatgaa tctgctccac cttgtatcag ctctaattct tcatttgtta
    22921 gatttatatt ttttgtcatt aaaatcatga tatatttcc
//
LOCUS       DAVKUR010000031        22675 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKUR010000031 DAVKUR010000000
VERSION     DAVKUR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.031"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            862..1920
                     /locus_tag="VW749_001354"
     CDS             862..1920
                     /locus_tag="VW749_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175384.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2234..3211
                     /locus_tag="VW749_001355"
     CDS             2234..3211
                     /locus_tag="VW749_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175385.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            3588..3962
                     /locus_tag="VW749_001356"
     CDS             3588..3962
                     /locus_tag="VW749_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0175386.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4170..5072
                     /locus_tag="VW749_001357"
     CDS             4170..5072
                     /locus_tag="VW749_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175387.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5128..5481
                     /locus_tag="VW749_001358"
     CDS             5128..5481
                     /locus_tag="VW749_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0175388.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            5478..6206
                     /locus_tag="VW749_001359"
     CDS             5478..6206
                     /locus_tag="VW749_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175389.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            7342..7581
                     /locus_tag="VW749_001360"
     CDS             7342..7581
                     /locus_tag="VW749_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175390.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            7566..7844
                     /locus_tag="VW749_001361"
     CDS             7566..7844
                     /locus_tag="VW749_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175391.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            8129..9967
                     /locus_tag="VW749_001362"
     CDS             8129..9967
                     /locus_tag="VW749_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV0175392.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASSPTVVRAEEAPVASQSKAEK
                     DYDTAKRDAENAKKALEEAKRAQEKYADYQRRIEEKAAKETQASLEQQEANKDYQLKL
                     KKYLDGRNLSNSSVLKKEMEEAEKKDKEKQAEFNKIRREIVVPNPQELEMARRKSEVA
                     KAKESGLVKRVEEAEKKVTEARQKLDAERAKEVVLQAKIAELENEVHKLEQKLKEIDE
                     SDSEDYVKEGFRAPLQSELDAKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDG
                     EQAGQYLAAAEEDLIAKKAELEQTEADLKKAVNEPEKPAPAPAPAPETPAPEAPAEQP
                     KPAPETPAPAPKPEKPAEQPKPEKPADQQAEEDYARRSEEEYNRLTQQQPAPAPKPEQ
                     PAKPEKPAEEPTQPEKPATPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANG
                     SMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNSNGAMATGWLQYNGSWYYLN
                     ANGDMATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYY
                     LEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            10368..11489
                     /gene="mnmA"
                     /locus_tag="VW749_001363"
     CDS             10368..11489
                     /gene="mnmA"
                     /locus_tag="VW749_001363"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0175393.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            11630..12085
                     /locus_tag="VW749_001364"
     CDS             11630..12085
                     /locus_tag="VW749_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0175394.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKSQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            12095..14008
                     /gene="mnmG"
                     /locus_tag="VW749_001365"
     CDS             12095..14008
                     /gene="mnmG"
                     /locus_tag="VW749_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0175395.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVSCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            14212..14289
                     /locus_tag="VW749_001366"
                     /pseudo
     CDS             14212..14289
                     /locus_tag="VW749_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(14387..16066)
                     /locus_tag="VW749_001367"
     CDS             complement(14387..16066)
                     /locus_tag="VW749_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0175396.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(16068..16301)
                     /locus_tag="VW749_001368"
     CDS             complement(16068..16301)
                     /locus_tag="VW749_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0175397.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            16581..16796
                     /locus_tag="VW749_001369"
     CDS             16581..16796
                     /locus_tag="VW749_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175398.1"
                     /translation="MYNLFAFAIGVRLLAFIVFVACVYGGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(17119..17271)
                     /gene="cibB"
                     /locus_tag="VW749_001370"
     CDS             complement(17119..17271)
                     /gene="cibB"
                     /locus_tag="VW749_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0175399.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(17273..17458)
                     /gene="cibA"
                     /locus_tag="VW749_001371"
     CDS             complement(17273..17458)
                     /gene="cibA"
                     /locus_tag="VW749_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0175400.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            17636..18319
                     /gene="tsaB"
                     /locus_tag="VW749_001372"
     CDS             17636..18319
                     /gene="tsaB"
                     /locus_tag="VW749_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0175401.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            18316..18753
                     /gene="rimI"
                     /locus_tag="VW749_001373"
     CDS             18316..18753
                     /gene="rimI"
                     /locus_tag="VW749_001373"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0175402.1"
                     /translation="MIEIKRIQQHPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            18743..19753
                     /gene="tsaD"
                     /locus_tag="VW749_001374"
     CDS             18743..19753
                     /gene="tsaD"
                     /locus_tag="VW749_001374"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0175403.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHELPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(19793..21099)
                     /locus_tag="VW749_001375"
                     /pseudo
     CDS             complement(19793..21099)
                     /locus_tag="VW749_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(21432..21726)
                     /locus_tag="VW749_001376"
                     /pseudo
     CDS             complement(21432..21726)
                     /locus_tag="VW749_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21833..22126)
                     /locus_tag="VW749_001377"
                     /pseudo
     CDS             complement(21833..22126)
                     /locus_tag="VW749_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            22369..>22675
                     /locus_tag="VW749_001378"
     CDS             22369..>22675
                     /locus_tag="VW749_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0175404.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     "
BASE COUNT         7010 a         3877 c         4827 g         6961 t
ORIGIN      
        1 caactaggtc attagatttt attgaagata taaattaaaa acgaggttgg gaaaaaactc
       61 aatttgaaag tgagattgag taaatctttc tatctatata atgtatatca tcaatatttt
      121 tgaacacctg ataatatgca cttttcttat tttaaagatt ttttgccttt attcatttct
      181 tgaatgaatt ggagagatga ctttatttag gtgtttgaca ttactataga taggatttag
      241 cagtactaat atgaactcat attataggtg tagacttaaa ttttggaagc aagctaaagg
      301 atatcttatc taggtaacta agtgctataa caagatatat tggtggagtt agtatggcaa
      361 ctattactaa tgctcttaat attgtggcta ctgttgctga agtcttctca ttaggaggag
      421 ccattgcata tggtttagat atcgtagacg gtaaatttga tgggtattta tgggcgtaaa
      481 actatagcta tgaaacattt ttttgcagga attggtgaaa ttcatttttt gttattttta
      541 ttatatctaa gcatgtctgc tagtccaatt attggactag tgattggata tactaaaata
      601 aatctaataa attctattat tatagctctt ggtatgatat tggcattaat tttggtatta
      661 tcaagagtgt atagaaaata tttttataga gacgatgatg actaaagttt ttatcaataa
      721 tttgggctcc ttgtcaactg tagtgggttg aataaaagct aacgtctggg gaagggttta
      781 aagctttgct ttatcaaata ttgacttaca gagttgctct attgtattga tgcattctta
      841 gtaaataata tggtgtttta aatgaaagat gatcagaaat atttattagc gggactttat
      901 tcgcttctag ttgcaatatt ttattttcca ttgattgatt ccaaggggat ttttgtaagt
      961 atattgatgg cggttttact tttatattta atatacttca ttgcaacagt cattcatatt
     1021 gtgataatta agtttataag aaaaaaatct tttaagtatt tggttctata tccatttact
     1081 tatgatggga gctggagatt tcaacctata aacttactct actttccaga aatggtgaga
     1141 gatgtcattc cgattaattt agttcaagaa tattgccaag gacaacctta cggactgtta
     1201 aaaaagatgc tgaaaagaat tcgattgtca cgagagatat ctttactcct ggctaccatt
     1261 atcgtctatt tttttacgca tagaattcta cctctttcag tatttacgtt catattttct
     1321 tacatattgc tatttgcaca atcttatttg ggtggtaata ccgcttggat tggaaataga
     1381 agattaataa tagatgatga atttgaaaaa atcttgcttt caaaaagtta tataaaagaa
     1441 atatcatctg cacgatactc agaatacttg acatgtgaat acaaaaactt tacaccaatc
     1501 atattgttag ctatttttga aaatttgctt gactcctact tgcttcagaa tcagagtgag
     1561 gttgacttag atatttttta taaagtttta cctttgcttt ataaagaaaa atatactatg
     1621 ggattcaatt actttgtaag tttaaattat ttactatata aggttggatt tttgggaatc
     1681 atttacgata atgaagcatt aagagatttg tcaaaacaat atttaaacaa aaatatttcg
     1741 gaattacaag atggttcttt cgaggacggt atacaagatg ctgttgcctc taaacaaata
     1801 gtagttataa atgaatttat agcttgttta aattccagat gcgtgccatc ccaatatgat
     1861 agattttttt ataaagatag accttatatt ttttccagaa agagtcctat taaggggtga
     1921 aaatttgtta catttggatt aacaagtgtc ctagggatta gaaataactc tagtatagct
     1981 agatattttt gagtaactag aaatatcatt agtctaccca tatgattgcc agaaaagatg
     2041 gctgatgaat cttatttata ctgttgcagt aggcgttgtc taggataaat aagctatctt
     2101 gatgggggag attggaataa ttttagtaga aacattaaag gattatggac aagtagcgca
     2161 ggattaggtg atgcaatgtg ctaagttggc ttggtgttag cagtagtatt atttaacaat
     2221 ggaaagtaga ctaatgaaaa ataagcgtta tttttttgac acaattttaa taattttact
     2281 gcttataagc acgatatttt gtgtcagccc agtatttata aaattggaca tcttaggaac
     2341 tccctctcat gccatcttaa cctttgtatt ggcgataccg ttattctata ttttgtctca
     2401 atgcttacat actttgctat tactagtttc ctcaatcttt tgtaaattaa gaccaattta
     2461 tttttatttt atatttgtga tcattatagg agctaggaaa tactatcgaa ttctctttca
     2521 ccaactaatg ggatttagtc caggaatagc agtgttttat aaggagagtc aaacaactaa
     2581 gaatctgttt aaattttact acttcttgta ctttacaaca ctaatttcat actatttttt
     2641 ctttactttt gtgtatgaca aatcgttgct tttgcctctt attccatttt ctattatcat
     2701 agcattagta caaaaacttt atagaattga gaatcaacaa ttatttctgt taaaatcaaa
     2761 agtactaaca atactggaat ctaagaggga ttgtgagttt aatcttcagg attatcatga
     2821 aatttggaaa ttgcaatcaa aatctgagtt gccatgcgtg gctttatctt atatcagttt
     2881 gatcaagcca tatctttcag agagtgtgcg tgaacaaatt gatttattag aagttaagcg
     2941 atttaaaaaa ataaatcatc caatatcact ttatggtatg ttggatgtta taaaattaaa
     3001 tctatattta cggcattata atgaaaaaaa taaatatgaa tcaatgttaa agaaaatttt
     3061 agaggtaaga ccagactttg ttttaatcga gcagaatatt gatgatagtt taaatagctc
     3121 gcaaccctta tctttatctt tagccatttc agaaatccaa cttttgcttg aagtgtatat
     3181 ggggatcaaa catgtttcaa ttaggagata aaaccagaat aatatttgcc attatagggg
     3241 caagttgcat attagtcagt atgtatctta ttccacttat taaaactgag aataaatttt
     3301 gggaaatact tttatttata ttaggtgtat tgctaattgg aattgcgtta ctaagtcaaa
     3361 aaaaataaat tttgaaatag tattagtgag ttcgcaatta tttattgcta gtggtttaga
     3421 actgttaagt ttcaaacaat aattgatttt aaaccttagg taacctataa aaacaaataa
     3481 ggtagagaaa ggatatctta tataggtagc taagtgataa aaacacagtc gtctatcact
     3541 tgttaggaaa ctatcctaac tatgcttaat aaaaaaggag aaaataaatg gaactcgtat
     3601 taccaaataa ttatgttgct cttgagcaag aagagatgat gtatcttgat gggggatttt
     3661 ctattctgag atggcctgtt gcaacagcca ttaatatagc ttttaatggt gttttaggtg
     3721 gaggagcaat cagtctagtt agaaattata ttcgtaatta tggtttgcgg cgagttacaa
     3781 gcgcaattgc tggagcagct gcaagatatg ttggggtacg agttgcaaat agagtggcag
     3841 gatttgcact gtctgctatt aatggatttg cagcttggat gtcaattggc gatgctatta
     3901 caacaatctg ggccaacaat gatgtaaata ggagagaccc aaatttaaac gccttgtggt
     3961 aactagatat gggtattaaa atggaaaaaa tttttgttat tatttttttt gtatgtctat
     4021 ttatatcatc cataactttt ttagcctatg attttgttag cgaagaaata aaaaaattga
     4081 ttatttggat gaatgtcgtt tttttgattt taatcatagc aatgataatt tatccaaaat
     4141 taagaaaatg ataaggacac tgtaaaatta tgatacgtaa actaatcatt tttttattaa
     4201 tgctccctct ttttgtcttg tggctagagt tgcatgtcct agtgaataac ttactattga
     4261 atctagaatc tccccttgat tttgtgatta gtatgagtct tgctttctgt agtttgattt
     4321 tatcaaaaat agttttagac atactatacg cattgaaaga tttgtacaag aaagaagctc
     4381 ttattacgat ttttcctttt atttttatag gcaggaagaa agtaaatgtg aggttctcgc
     4441 cctatttttc attccatcgt aaaagtttgt cgcctgatga tttaagatct aggattatat
     4501 ggagttttat tcttgaaatt gctattatcc tagtatttat tttaaaaatt ccttttgcaa
     4561 tcatcatgct tactacaata tttttctgga ctataatgga tatcaatcat ctcgttttta
     4621 ataagacgga atttcttttc aatcaaaata aatgggaaaa agaagattcg tttgaaagtg
     4681 atttgacaaa tacgttaaag gataaaatac aaaaatcaga tctcagttat tctgacttaa
     4741 tgtctcttca gctgtatgat gcgatgaatc aatctacctt tttaacggat agtgaactct
     4801 ttgaggatat tctgagtaaa attgaagatt ctcataacac ccttctgtgt acaggtcttg
     4861 tcgagttact gctgtatgag atttctatta gtaacaataa caactggtcc aacaaggttg
     4921 ataaaattag gatacacctc atcagaatca atcaattaga ttttttctat tatacaagtt
     4981 ggttaaggca aaattttgat ttctgtatga atagagagta tcataaaatg aaatctcgga
     5041 aattattact gagtaataaa aagatagttt aagttcgtcc tatttgtaaa acaaatgaaa
     5101 caatttcaac taaggaggag aaaacaaatg gaacttgtat taccaaataa ttatgttgtg
     5161 attgatgaag aagaaatgat gtatcttgat gggggggctt atttaagcaa gagtgattgt
     5221 caaggaattt gtgcagcttt agctatgagc ccaggaactt ttatagcatt agctggatct
     5281 gcagttttaa ctaaaaaact aataaactat attaagtttg gaggtcttgg aggctggctt
     5341 attggtgcag cagcaggtgt attggctaca gcagcaggaa aaatagctta ctgtattgga
     5401 tatggtgctc ttaatagagg ttgtgatatt agcgggaacc cttatccttg ggatggattc
     5461 atatctgcga cagtaagatg aataatgtag ataagattcg aaaaatacat attatcgtat
     5521 gttggatgta tatattttta tcattcaggg cgattataaa tgacacggag tattttttgc
     5581 ttattttttt agcttttatc tactcaatag tatcactacc tctatattct gtgaaaaata
     5641 aaatagtatc tatctgtcta gccataaatt cgattctgtt aatgagtttc cccattttaa
     5701 tcaataagtt tttcccagaa agttttttga cttataccgt attaataagt gtttttatcc
     5761 tagagttagc aatctttcat ttaattgggg aagattttgc tactaaattg actaacgaat
     5821 ataagaaaat tagtcagttt agaagcaagg tgtctcaatc tccttggata aaatatttag
     5881 agatttctag ttttatatta actatatttc catctattct ttacggtaca gttgataatc
     5941 gtgtattggc tcttatcttt ttgataaaaa tttgtgtaga tactacgata aaatttttat
     6001 tcatcagatt atttgacaca agtactttaa tgaagaggag aatatttttt cttttcgcat
     6061 tggatgttat agcttactta tttttaggat atcttttagt gattcaaaaa gcaggctatt
     6121 tgttttcggt tttacttctt ttttctaatt tttcagttcc atttatcaaa gcaaaggaat
     6181 acgaattatt taaaaatagc aagtaataga aacataggtt aaatcttaga acggcttaaa
     6241 atcagatatg ataaagggaa atagtcttat ctaggtaact aagtgctaca aacacagtcg
     6301 aggatcactt gttaggatta cattttaatc atgcttaata agaatggaga attcctatgg
     6361 ggattgtatt actctgaagt ttcgaatacc ttagttctcg tgattttgag ctgttctagc
     6421 tttagaatcc ttcagaatgt aaaattttaa gcagtcaaag acttagaata gcctggaaac
     6481 atttatttta tagcaattct aggcttagaa ttgctcatat atatgtattt gagctgctcg
     6541 atagttagga cagctctatt ctgagaaatc tgagctatca atgcttcaga atagtatttc
     6601 gcaaatggtt tttattgaag aggtgattgt tttatgatag tctaaaataa aactgattta
     6661 atggagtaaa tggagaatcg tcacatgaaa catttttttg caggaattgg tgagataaaa
     6721 cttgttggct acttattgta tatatgtgta ggactagccc ctctttttca tatatatgtc
     6781 ataggttcgg aactgagttt tgtgaaaata gtgttatcta ttttgggagt tatatttgta
     6841 agtatgttaa ctattgctcg aatttatagg acttttttct ataaagaata gtttggactt
     6901 gaactgtatc taaaaacaga ggttggtcga ttatcagcct ctttcttgtc gttgaaaaga
     6961 gtgagatata ttgacttttg aaaaaaagat gtcataattg agttgggata aacctaaaag
     7021 taatatagta gattgaatct ggaatagtcc gttatgactg ttaaaatatt tctagaaatt
     7081 aatttgactt tcctaatcga tttgttcaca tcttgtttca atctactata ctttctcgtt
     7141 aaaccgttcg gcaattcatg gtgacatgga cacatggtag taagcacact atgtggcttg
     7201 gcagagctaa aaactgttcc cttgcgataa gcctaataag cacaacatag ggagttagag
     7261 aagccgactc taatcaacca ctttgggcag tagtgagaac tgccccgtgc tttttatttt
     7321 gagaaaatat ggagtttgtc gttgaaatta cttgattgta ttttggacta tcaagaaaga
     7381 ttcaatggaa aaacatgtca agtatcaacg aattataagt atttagagat tttcaaagtg
     7441 aatttttgct tgactgattt acatcattta tttgacttat acaaaatcac acgagattat
     7501 gctagtcaaa caaaacctgc tattcaagct ggtgttttta ttttagaaga ttttagaaat
     7561 atcctatgta caatgatgta atcgaaagga tatctttata tgagtttatc ggtgatattt
     7621 tctattctaa aataataagt tgttgcatcg tagctaggga tttatctaaa aatactatga
     7681 aattggacgt catatttttt gaggataaaa ataaaagatc cgcagtttta ggtttacgaa
     7741 gagacaaaag cggagtattt aaaccagtta ctctacattt tacaagcgct aagaaatatg
     7801 ctaaagttcg taaaacagat gtgaaagaaa tgaaatggct ataaagattg tccgcaggct
     7861 taagcttgcg ttttttgttg tttaacgaaa ttaaaaaaca agctctttca tcgaaaatgt
     7921 ttttatagga atgaaggaag atgatgctat gtttaaaaag agaatcgaaa agggcaaaag
     7981 tagtatcttt atctttttgg agtagaagtt atgatataga aatttgtaat aaaaatgtaa
     8041 tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta tagtctaaaa
     8101 atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt taacaagtct
     8161 agccagcgtc gctatcttag gggctggttt tgttgcgtct tcgcctactg ttgtaagagc
     8221 agaagaagcc cccgtagcta gtcagtctaa agctgagaaa gactatgata cagcgaagag
     8281 agacgctgag aatgcgaaaa aagctttaga agaagcaaaa cgtgcgcagg aaaaatatgc
     8341 cgattatcag aggagaattg aggagaaagc ggcaaaagaa acacaagctt ctctagagca
     8401 acaagaagca aataaggact atcaattaaa gttgaagaaa tatcttgacg gaaggaacct
     8461 ctcaaatagt tctgtgttaa agaaagaaat ggaggaagct gagaaaaaag ataaggaaaa
     8521 acaagcagaa tttaataaga ttagacgaga gatagtggtt cctaacccgc aagagttaga
     8581 aatggctaga cgaaaatcag aagtggctaa agcaaaagaa tcaggacttg ttaaaagagt
     8641 agaagaagct gagaaaaaag ttactgaagc cagacaaaaa ttggatgctg aacgtgctaa
     8701 agaagttgtt cttcaagcca aaatcgctga gttggaaaat gaagttcata aactagaaca
     8761 aaagctcaaa gagattgatg agtctgattc agaagattat gttaaagaag gtttccgtgc
     8821 tcctcttcaa tctgaattgg atgctaagca agctaaacta tcaaaacttg aagagttgag
     8881 tgataagatt gatgagttag acgctgaaat tgcaaaactt gaaaaagatg tagaagattt
     8941 caaaaactca gacggtgagc aagctggaca ataccttgct gcagctgaag aagacttaat
     9001 tgctaaaaaa gctgaattag aacaaactga agctgacctt aagaaagcag ttaatgagcc
     9061 agaaaaacca gctccagctc cagctccagc tccagaaact ccagccccag aagcaccagc
     9121 tgaacaacca aaaccagctc cagaaactcc agctccagca ccaaaaccag agaagccagc
     9181 tgaacaacca aaaccagaaa aaccagctga tcaacaagct gaagaagact atgctcgtag
     9241 atcagaagaa gaatataacc gcttgactca acagcaacca gctccagctc caaaaccaga
     9301 gcaaccagct aagccggaga aaccagctga agagcctact caaccagaaa aaccagccac
     9361 tccaaaaaca ggctggaaac aagaaaacgg tatgtggtat ttctacaata ctgatggttc
     9421 aatggcaaca ggttggctcc aaaacaacgg ttcatggtac tacctcaacg ctaacggttc
     9481 aatggcaaca ggttgggtga aagatggaga tacctggtac tatcttgaag catcaggtgc
     9541 tatgaaagca agccaatggt tcaaagtatc agataaatgg tactatgtca acagcaatgg
     9601 cgctatggcg acaggctggc tccaatacaa tggctcatgg tactacctca acgctaatgg
     9661 tgatatggcg acaggatggg ctaaagtcaa cggttcatgg tactacctaa acgctaacgg
     9721 tgctatggct acaggttggg ctaaagtcaa cggttcatgg tattacctca acgctaacgg
     9781 ttcaatggca acaggttggg tgaaagatgg agatacctgg tactatcttg aagcatcagg
     9841 tgctatgaaa gcaagccaat ggttcaaagt atcagataaa tggtactatg tcaatggctt
     9901 aggtgccctt gcagtcaaca caactgtaga tggctatgaa gtcaatgcca atggtgaatg
     9961 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
    10021 agataaggtt cgattgaata aatttatgtt cgtattcttt aggtacctat cttatgattt
    10081 caggaaatgt tattaaaaaa acgactcctt ttctctaact tgaaaaatag attagagaaa
    10141 atgggttgtt ttatttatta tagttatttg aatgaagata agaagaaggt atactcacgt
    10201 cattcacata atctgtatat tgactataag ttttaaaaaa caatttttaa gctcttcctt
    10261 gtcttctcta accaagcgtg ttataatgaa tactgctcaa gcgaccttca atcgtgaagc
    10321 acacacgacc ttcaatcgtg aataaacgaa tagatgggag acttaccatg agtgataact
    10381 ctaaaacacg tgttgtcgtg gggatgagtg gtggtgttga ttcgtcggtg acggctcttt
    10441 tgctcaagga gcagggctac gatgtgatcg gtatcttcat gaagaactgg gatgacacag
    10501 atgaaaacgg cgtctgtacg gcgaccgaag attacaagga tgtggctgcg gtggcagacc
    10561 agattggcat tccctactac tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg
    10621 agtatttcct agcggaatac cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca
    10681 aggaaatcaa gttcaaggcc tttttggact atgctatgac cttgggggca gactatgtag
    10741 cgactgggca ttatgctcga gtggtgcgtg atgaggatgg taccgttcac atgcttcgtg
    10801 gcgtggacaa tggcaaggat cagacctatt tcctcagcca actttcgcaa gaacaacttc
    10861 aaaaaaccat gttcccacta ggacatttgg aaaagcctga agttcgaaaa ctagcagaag
    10921 aagcaggtct ttcgactgct aagaagaaag actcgacagg gatttgcttt atcggagaaa
    10981 agaactttaa aaactttctc agcaactacc tgccagctca gcctggtcgc atgatgactg
    11041 tggatggtcg cgatatgggc gagcatgcag gtcttatgta ctatacgatt ggtcagcgtg
    11101 gcgggcttgg tatcggtgga caacacggtg gtgacaacgc gccgtggttc gttgtcggaa
    11161 aagacctgag caagaatatt ctctatgtag gccaaggttt ctaccatgat tcgctcatgt
    11221 caactagcct agaggctagc caagtccact ttactcgtga tatgcccgag gagtttacgc
    11281 tagaatgtac ggctaaattc cgttaccgtc agcctgactc taaggtgacc gtccatgtca
    11341 aaggagacaa ggcagaagtt atctttgcgg aaccacaacg cgcgattaca ccaggacagg
    11401 cagttgtctt ttacgatggc gaagagtgtc taggtggcgg tttgattgac aatgcttacc
    11461 gcgatggaca agtttgtcag tacatttaga ttgacaaatt ttctcaattt gctacaataa
    11521 taacagcaat agaaatgatg gtcaaagctc atggatgttg caggcttttt tgtcctgcac
    11581 ttctttgtag ttttgactgt ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca
    11641 agactttcgg acaaaagtag acaatacggt ttttggtgtt cgggcgacag ctttgattct
    11701 tcaaaatcgc aagcttctag tcaccaaaga caagggcaag tattacatta tcggcggtgc
    11761 gattcaagtt aacgaaaaaa cggaagacgc ggtagtccgt gaagtgaagg aagaactggg
    11821 tgttaaatct caagctgggc agctagcttt tgtggttgaa aatcgttttg aacaagacgg
    11881 cgtttcctat cacaatatcg agtttcatta tctggtggat ttgcttgaag atgccccgtt
    11941 gaccatgcag gaagatgaga aaaggcagcc ctgtgagtgg attgacttgg ataagcttga
    12001 ggatatccag ctagttccag cctttttaaa aacggcccta ccagattggg aaggccaact
    12061 aagacacatt catcttgaag aataggagag aaacatgact tatcatttta ctgaagaata
    12121 cgatattatt gtaattggtg cgggacacgc tggggttgag gcttccttgg ccgctagccg
    12181 tatgggctgt aaggtcctgc ttgcgaccat caatattgaa atgctggctt tcatgccttg
    12241 taatccctct atcggtggtt ctgccaaggg gattgtcgtg cgtgaagtcg atgccctcgg
    12301 tggcgagatg gccaaaacca ttgacaagac ttacatccag atgaagatgc taaacacagg
    12361 gaaggggcca gctgtccgtg cccttcgtgc gcaggctgac aaggaacttt actctaagga
    12421 gatgcgcaag acggttgaaa accaagaaaa tctgaccctt cgtcaaacca tgattgatga
    12481 gattttggtg gaagatggca aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc
    12541 tgctaaggct gttattgtga cgacagggac tgctctccgt ggggaaatta tcatcggaga
    12601 cctcaagtac tcatcaggtc ctaaccacag cttggcttct attaacctag ctgacaatct
    12661 caaggaactg ggtctcgaaa tcggtcgttt caagacagga acccctccac gtgtcaaggc
    12721 ctcttctatc aactacgacg tgacagaaat ccaaccagga gatgaagcgc ctaatcactt
    12781 ctcatacact tcacgtgatg aggattatgt caaggaccaa gtgtcatgct ggttgaccta
    12841 taccaatggt accagtcatg agattatcca aaacaacctc caccgtgcgc ctatgtttac
    12901 aggtgtggtc aagggagtgg ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg
    12961 ctttgcggac aaggaacgtc accaactctt ccttgagcca gaagggcgca atactgagga
    13021 agtctatgtt caaggacttt caaccagtct gcctgaggat gtccagcgtg acttggttca
    13081 ttccatcaaa ggtttggaaa atgcagagat gatgcggaca ggttatgcta ttgagtatga
    13141 tatggtcttg cctcatcagt tgcgtgcgac tctggaaacc aagaaaatct caggtctctt
    13201 cactgctggt cagacaaatg gaacatcagg ttatgaagaa gctgctggcc aagggattat
    13261 cgcgggtatc aatgcggctc tgaaaatcca aggcaagcct gagttgattt tgaagcgcag
    13321 tgacggttat atcggggtga tgatcgacga cttggtgacc aagggaacca ttgaacccta
    13381 ccgtctcttg acaagtcgtg ctgaataccg tctcattctt cgtcatgaca atgctgatat
    13441 gcgcttgact gagatgggac gcgagattgg ccttgtggat gatgaacgct gggctcgttt
    13501 tgaaatcaag aaaaatcaat ttgataatga gatgaaacgc ctagacagta tcaaactcaa
    13561 gccagtcaag gaaaccaatg ctaaggttga ggaaatgggc ttcaagccgt tgacagatgc
    13621 ggtgacagcc aaagaattcc ttcgccgtcc agaagtttct taccaagatg tggtggcctt
    13681 catcggacca gctgcagaag acttggatga caagattatc gaattgattg aaacagaaat
    13741 caagtacgaa ggctatattt ccaaagccat ggatcaggtt gccaagatga aacgtatgga
    13801 agaaaaacgc attccagcca atatcgactg ggatgacatc gattctattg cgacggaagc
    13861 tcgtcagaag ttcaaactca tcaatccaga aaccatcggc caagccagcc gtatttcggg
    13921 agtaaaccca gcagatattt ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat
    13981 ttctaaaact cttcaaaaat caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa
    14041 gcttggcttt gattcatctc caacctccca tagttccccg aactatggga gctaactcaa
    14101 gttatgcttt cgcttagcct tctagtctga ttttcattga gttttaatct caaaagaaag
    14161 catagagaaa aacagctccg aagacggggc tgttttgttg atttgtactc aatgaaaatc
    14221 aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc actgctttga ggttgtggat
    14281 agaactgacg aagtcagctc aaaacacagt tttgaggttg tggatagaac tgacgaagtc
    14341 agtaacatat atacggcaag gcgaagctga cgtggtttga agagtattat tcttcatctg
    14401 gtgtgaggat catcgggatg atgatcggtt cacgttcggt attttcatag aggaaggggc
    14461 gaatagcgtt gacaatggca ccattgacag attgcacgct agcatcctta tttttcagtg
    14521 cgatacgaat ggcattgaag aggatacgct ggctttggcg aatcaagtcg ccagactctc
    14581 tcatgtagac aaagcctcgg ctgaggatgt ctggaccaga tagaatcatc tgcgatttga
    14641 agtcaacagt tgcgactgcc agaacgacac cgtcttcaga tagatcgcga cgatctttga
    14701 ggacagctgc gccaatttca ccgatacgat ttccatcgac atagatatct tgggcgttga
    14761 aatgacctgc gatacgagct gagtcagcag taagggcaag cacatcgcca ttgctcatga
    14821 taaagatatt gtccttctca acaccagtat ccactgctag tccagcgtgg actttttgca
    14881 tgcggtattc accgtggaca ggcatgaagt attttggctt aatcaagcag agcatgagtt
    14941 tttgctcttg ctgaccaccg tgtccagatg tatggatatt gtttacttta ccgtggataa
    15001 cttcgacacc agcttcagaa atgatgttaa tcagcttgtt gacgctagta gtgtttccag
    15061 ggatgggact agaagagaag ataacggtat cacctggttg taattgtact tgacggtggg
    15121 ttccgttggc gatacgagag agggctgcca taggctcacc ctgactacct gtacagagga
    15181 taagaacttc tcctgcagga taatctttga tttcatttgg ctcgataaag gttcccttag
    15241 gagctttgat gtagccaaga tcgattccgt tgacaatggc cttttccata gaacgaccaa
    15301 agaccgcaat cttgcgtcca gtcttaacag cagcttctgt tgcctgctgg agacggaaga
    15361 tatttgaggc aaaggatgca aagatgatac gtccttcaat accttggata atcttcataa
    15421 tggactgacc aacgactttt tcagagttgg taaaggttgg tacttccgca tttgtcgagt
    15481 cagacaggag acagagcacg ccttcttcac caagcgcagc catacgatgc aagtccgcag
    15541 gttctccaac tggagtaaag tcgaacttaa agtcacccgt acagacgatt ttcccttgag
    15601 gagtatgaat gacaatcccc aaaggctctg gaatagagtg agtcgttcta aagaaagttg
    15661 ccttgagatt tttaaaggtc aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc
    15721 gcaagaggcc gtgttcttcg agtttcccac ggatcaaagc caaggcaagc ggtccagcgt
    15781 agatagggac atttgcttgc ttgagtagga acggaatccc accaatgtgg tcctcgtgtc
    15841 cgtgtgtgat taaaacagcc ttgacgcggt cgatattgtc cacgatgtaa gagtagtcag
    15901 gaatgacata gtcgatacca agcaagtcat cttctgggaa tttaatccca gcatcgacga
    15961 tgataatctc gtcttggtat tcaattccgt aagtgttttt cccgatttct cctagaccac
    16021 cgatggcaaa aacgccgact tcttcaggtt taagagtgta ggccatatta gaactccgta
    16081 atttcgaagg cgccagtttc tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata
    16141 tattcgatat tgtactctgg gcgattttct tcgacaagtt ggcgagcagt gatacggccc
    16201 tcaagttctg agctggcatc gatgtctagg taaagcgcgc gtgttgtttc acggcgtggg
    16261 ctacgttctt ttgtttcttg ataaaaaact ttgtaaatca tatagttcct ttctatttac
    16321 aggtcagctt attccaaact tttagcagag atttgcttga tttcattcca ttttgtgtct
    16381 agattgacct tgattcgtta caattatttc aattatacca caaaatgaaa aattagtaaa
    16441 agacggaaac gagaaagtta ggggacgatt tctttggtaa gcgtttgcaa aaataaagaa
    16501 aatgtattat gttgataacg gaagtgaaat ttattgcttg tcataattcc atatagattt
    16561 taagtcaagg aggttgccct atgtataact tatttgcttt tgctatcgga gttcgtttgc
    16621 tagcttttat cgtttttgtt gcttgcgttt atggaggaaa tcttctattt gccaaactgg
    16681 aacgacgaca aaccaagttc ttgtggaaaa tgacctttgt gactctctac tcgctttttc
    16741 tcctcctcgt gacctatgtc gtttggtttg tattttactt tgaattaaat gcttagatgc
    16801 cctgcttatg ctggggtttt ttgtttgggg atgtagagat agtagattta cgacacgaaa
    16861 attccacccc atctatcaag atgaggtggt ctttgcattt ttctaacatg acatgacaat
    16921 ggaattttca aagcttatta tttttatggg agtcattgtt ctgatcaaaa atagagttga
    16981 agcataaaaa taaaacaata caaacagata aatcgaatgg taaagggatg gtagtaatgt
    17041 tcaaatcatt gagaatgctg agcaaactgt aagagatgaa gacaataaaa tttatccttc
    17101 taaaaatgtg tttcttatct agcatgactt accaaacttt ttacgaaggt cttttccaat
    17161 ggtataacct gccataaata aagcgatacc aacaccgaca ccaaagccac ccttgatttc
    17221 ttgcaattcc ttattagaaa tttcacgata attgttcaaa tctttcatca tattaatctc
    17281 ctcctaaaaa ataaccagct gccaaaccag aacctataag tgctgttcca cctgcaatag
    17341 ccttccaaga tactgctact ccaaagataa ccaagggagc gagaccgcca tcaatatctg
    17401 ataattcatt ttcagataag gataaaaatt gattgtcaag aatgtcaaaa tttgtcattg
    17461 aactttcctc cttttttctt gttcactttt atattcggaa aagaaaagga aaagtgagca
    17521 tttttttaaa ttatttttag ttaagtgagg gcactcttgt ctgggggcaa agaaaattcc
    17581 catgtgccag cttttgtagt ataatagtaa gcagacaaaa agataggaat gtgttatgaa
    17641 agtattagct tttgatacgt ccagcaaggc tctttctctg gctattttag aggataagca
    17701 ggttcttgcc gagacgacga ttaatattaa gaaaaatcac agtattactc ttatgcctgc
    17761 catcgatttt ttgatggcaa gtttggattg gacacccaag gatttggacc gaatcgtggt
    17821 agctgaaggg ccgggtagct atacaggctt gcgaattgcg gtagcaactg ctaagacctt
    17881 agcttacacc ctgaacatcg agttggttgg tatgtcgagt ctcttggctc tggtgcccca
    17941 ccaacaagaa ggtttgtttg tccccttgat ggatgcgcgt cgcaataatg tttatgcagg
    18001 attttatgaa aatgccaaac ctgtcatggc agaagcgcac ctatcttttg aagaggtgct
    18061 agaaaaagtc aagggtacta gtcaggtaac ctttgtcgga gaagttggcc cctttgttga
    18121 gcagattcaa aaacacttgc caaggactga ttacaaagaa acattgccca atgcagccaa
    18181 tcttgctctt ttagcttggg acaaggaagc agactccttg catgattttg tgccgaacta
    18241 cctcaagcgt gtcgaagctg aggaaaactg gctcaagaat cacaccgagt ctggtgagtc
    18301 ctacattaaa cgcctatgat agaaatcaag cgaattcaac aacatcctga cctagctcaa
    18361 gccatctacg ctgttatggc agctgtttac ctagtcagtc cttggactct ggagcaaatc
    18421 caagcagatc tgtcccaaga ccagacttgg tatgcattgg cttatgatgg ggcagaagtg
    18481 attggatttc tagctgtgca ggagaatctt tttgaagcag aagtcctgca aatcgctgtc
    18541 aaaggagctt atcagggtca gggaattgcg tcagccttgt ttgctcaatt gccgacagac
    18601 aaggaaattt tcctcgaagt cagacagtca aatcaacgag cgcaagcatt ttacaagaaa
    18661 gaaaagatgg cagttatcgc tgagcgaaag gcctactacc atgacccagt cgaggacgcc
    18721 attatcatga agagagaaat agatgaagga tagatatatt ttagcatttg agacatcctg
    18781 tgatgagacc agtgtcgccg tcttgaaaaa cgacgatgag ctcttgtcca atgtcattgc
    18841 tagtcaaatt gagagtcaca aacgttttgg tggcgtagtg cccgaagtag ccagtcgtca
    18901 ccatgtcgag gtcattacag cctgtatcga ggaggcattg gcagaagcag ggattaccga
    18961 agaggacgtg acagctgttg cggttaccta cggaccaggc ttggtcggag ccttgctagt
    19021 tggtttgtca gctgccaagg cctttgcttg ggctcacgaa cttccactga ttcctgttaa
    19081 tcacatggct gggcacctca tggcagctca gagtgtggag cctttggagt ttcccttgct
    19141 agccctttta gtcagtggtg ggcacacaga gttggtctat gtttctgagg ctggcgatta
    19201 caagattgtt ggggagacac gagacgatgc agttggggag gcttatgaca aggtcggtcg
    19261 tgtcatgggc ttgacctatc ctgcaggtcg tgagattgac gagctggctc atcaggggca
    19321 ggatatttat gatttccccc gtgccatgat taaggaagat aatctggagt tctccttctc
    19381 aggtttgaaa tctgccttta tcaatcttca tcacaatgcc gagcaaaagg gagaaagcct
    19441 gtctacagaa gatttgtgtg cttccttcca agcagcagtt atggacattc tcatggcaaa
    19501 aaccaagaag gctttggaga aatatcctgt taaaacccta gttgtggcag gtggtgtggc
    19561 agccaataaa ggtctcagag aacgcctagc agccgaaatc acagatgtca aggttatcat
    19621 cccccctctg cgactctgcg gagacaatgc aggtatgatt gcctatgcca gcgtcagcga
    19681 gtggaacaaa gaaaactttg caaacttgga cctcaatgcc aaaccaagtc ttgcctttga
    19741 taccatggaa taaagagtgg ctctttgtca agtgtagtgg gtaggcgaaa agctacaatc
    19801 tggagagtac gaaattcgta ctctcttttt tgatgttcaa agtcatcaaa atccgttttt
    19861 taaaattgtt aaagttccgg aaaccaaagg ctttgcgctt gataacctta atcaaattat
    19921 tggtcgcttc aagtttagcg ttggaataag gcagcttaag tgcgttgata atcttatctc
    19981 tatcccttaa aaaagtccaa aagaccgttt gaaaaagcgg atgaaccgtt ggcagttctt
    20041 gctcaatcaa tccaaagaaa tggtcggcat tcttctcttg aaaatgaaag agcaggagtt
    20101 gatagagttc gtagtaaacc tgtaatccct cagagtaaga aagcagctta tctcgtactt
    20161 cccgatgggt taagtgcatt cgaaacgtgg gctgatagaa tcgtttctga cagagcttga
    20221 agctatcctg gtgtagtaaa tcagtccagt ggactgattt agcccgagcc tagaaacgaa
    20281 aaagcgaggg ttccaaaagc gcttgagcgc ccgatactcc aaggattttc ggtcaaattg
    20341 gttcatgatt tggattcgta ctcggttcat agctcggctc agatgttgga caatgtggaa
    20401 gcggtcaaga acaatcttcg cctttggaaa gagttgctta gcgagccgat aataagggct
    20461 gtacatgtcc atggtgatga cctcgaccag ctcccgaacc tctctctgat agcgttggaa
    20521 atggtttcga atcaccgcat gagttcgccc gtctaaaatt gcgaggatgg atttggactc
    20581 aaaatcttgg gcaatgaagc tcattttgct ctttttgaag ctatactcat cccaactcat
    20641 aacttttggc aacttggtcc aatcggtttc aaacttaaat tccctcagtt ttcggatgac
    20701 ggtggaagtt gagaccgcca atctgtgggc aatctcagtc atagactgct tttcaaggag
    20761 gagctgagcg attttttgtc tcaccatgtt ggaaatctgg caatttttct tgacaatgga
    20821 tgtttgagaa acgaccacct taaggcaatt cttgcactga aagcggcgct ttttgagatg
    20881 cagtaccgtg ggtaaaccct gacagtcgag aagcggaatt ttagaggctt tctggaagtc
    20941 gtatttgatc atcttccctt gacaatgagg acaaggagga gcgggggaat ccaactttgc
    21001 ctgaacgact agatgggttt ggtatttcag aacagacaag attttgatat ttttgtcttc
    21061 caatccgagc aaatctgtgg tattcttaag ttgttccata tgaacccttt ctaatgagtt
    21121 ggttagacgc ttttcattat aggtcatatg gggctttttt tctacaagaa acgaccctat
    21181 aattcctggg gtgggattac ccactacaga aattatagag ccaaagcatt ccaaagtctt
    21241 gtctgactct ggaatgtttt ctgttcacag ttgttttgta actgcctaat aagtaaccgc
    21301 gctataacga ggtatctacc gagattgtca attctccagt atactgttat aaaaaacaaa
    21361 actggaggat ttttttatgt ccccccatcg tcccatcgac tgttccgtag ctgcccaata
    21421 acggagtata atcagctgaa acaagaatag gacaaaagtg cctcaagaaa agcatcgtaa
    21481 tttgacaata ttattctgag atgtttttga tgtaagccca tattttctca atgggattat
    21541 actcgggtga atagatagga agtggtaaca gtctatgccc tgctccttac acatgttcat
    21601 tctgtgaaac cttgcattgt ccataatgat aagggatggt gtatctaaag taggtagtaa
    21661 gaatttttgg aagcaagctt cgaaaaagtc actcgtcatc gtatctttat aggtcatcgg
    21721 agccatagta tattgaaaca aaaaagggca ttagtacttc tataacagta tcgcaatctc
    21781 tggtgtgcgt tgtctcgatc ttaattcaaa taattatatc ttcttccaga gagactaact
    21841 gcctgctcaa ggctcgatca tattcgagat aaaaataggt cttaacccct gtctcataaa
    21901 tataaatagg agtcaggtag cttaagtgat tcaattcttt aaggaaccga tttacttttt
    21961 ctgggtcttg ttcgcagtag gtacggctct tttttagact atatcccata gcctttagag
    22021 cgtaatgaat agttgttgga gggcagttga attcagcagc tatttcagtc aaataagcat
    22081 cgggatgagt ttcaatatag atctttaatt tatctctatc aactttttca attaatagtg
    22141 gaagttttct taaagttagt gtgttgaaac gtttttatac agtgctaaaa tttgaagtgt
    22201 agtgcagatg tatttgtaat agtattatag caattctttg aagaaggtcg agacaagaga
    22261 aaataggtat ctttgagata taagcatgat ttactataaa attattgagt tattcataaa
    22321 aatttctcta tcaaatatca taatgcgtcg tttaaggaga tggttacaat gcaatatagt
    22381 tgtggaaaaa taaatattaa tatccctgat ggatatggag acattaagga tatagtgttt
    22441 tcggctcata ttatagttag gtataataat ggacattgtg gaggtataga tccgcatata
    22501 attggacttt gtaaaaagca gatcagaagg atgtctctat atcctatttt gataatcgta
    22561 tctagagatt caaaggttat tgatgattat aaaaatttag atattgccta tgttgattgt
    22621 actcaatgtt caaataattt tgaaactgcc ttacacgtta aaaatatttt aaaat
//
LOCUS       DAVKUR010000032        22542 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKUR010000032 DAVKUR010000000
VERSION     DAVKUR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.032"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            110..763
                     /locus_tag="VW749_001379"
     CDS             110..763
                     /locus_tag="VW749_001379"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0175405.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            773..1237
                     /locus_tag="VW749_001380"
     CDS             773..1237
                     /locus_tag="VW749_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0175406.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1250..2518
                     /locus_tag="VW749_001381"
     CDS             1250..2518
                     /locus_tag="VW749_001381"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0175407.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2532..2792
                     /locus_tag="VW749_001382"
     CDS             2532..2792
                     /locus_tag="VW749_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175408.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2803..4164
                     /gene="pdrM"
                     /locus_tag="VW749_001383"
     CDS             2803..4164
                     /gene="pdrM"
                     /locus_tag="VW749_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0175409.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4318..5286
                     /locus_tag="VW749_001384"
     CDS             4318..5286
                     /locus_tag="VW749_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0175410.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5302..6294
                     /locus_tag="VW749_001385"
     CDS             5302..6294
                     /locus_tag="VW749_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0175411.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6512..7555
                     /locus_tag="VW749_001386"
     CDS             6512..7555
                     /locus_tag="VW749_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0175412.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7619..9304
                     /gene="lpdA"
                     /locus_tag="VW749_001387"
     CDS             7619..9304
                     /gene="lpdA"
                     /locus_tag="VW749_001387"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0175413.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9368..10357
                     /locus_tag="VW749_001388"
     CDS             9368..10357
                     /locus_tag="VW749_001388"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0175414.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VW749_001389"
     CDS             complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VW749_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0175415.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12008..13558)
                     /locus_tag="VW749_001390"
     CDS             complement(12008..13558)
                     /locus_tag="VW749_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0175416.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13574..14353)
                     /locus_tag="VW749_001391"
     CDS             complement(13574..14353)
                     /locus_tag="VW749_001391"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0175417.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKEN"
     gene            complement(14340..15191)
                     /gene="ylqF"
                     /locus_tag="VW749_001392"
     CDS             complement(14340..15191)
                     /gene="ylqF"
                     /locus_tag="VW749_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0175418.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWCQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15437..20686)
                     /locus_tag="VW749_001393"
     CDS             complement(15437..20686)
                     /locus_tag="VW749_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0175419.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVIGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVT
                     SYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSA
                     NLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMI
                     YDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDV
                     KKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHY
                     IEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLL
                     SDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIEN
                     VKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVE
                     RAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVV
                     GSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSY
                     QRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYK
                     VDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDI
                     DHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKD
                     RLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVK
                     SLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFK
                     PDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFT
                     NDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAH
                     MFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQ
                     LLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGA
                     MASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAY
                     AQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDA
                     LMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINN
                     IDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINIMTGIYGGNTSQGAPGAASFKHNT
                     FRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYF
                     KDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLK
                     SKVFKALLKNTDGFFNKLFKEDI"
     gene            complement(20730..>22542)
                     /locus_tag="VW749_001394"
     CDS             complement(20730..>22542)
                     /locus_tag="VW749_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0175420.1"
                     /translation="KSGFNNLLAKNNVITYNVLLAKNYGTESLFKALEGYRKVFLPTI
                     SNNEWFKKQTKAYIVEEKSTIEEGREKQGKEGTKYSIGVYDRLTNPSWKYQSMVLPLL
                     TLPEEKTVFMIANISTIGFGAYDRYRSSEYPKGEKLNKFVEDNAKEAAKRFRDHYDYW
                     YKILDNDNKEKLYRSILVYDAFKFGTDKDKDKVTHQATFETDHPAIKYFFGPAGNNVV
                     HNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEFYA
                     KGLLQAPDHPYDPTITINSVLKYEDSENSTRLQVADPTQRFNSAEDLHNYMHNMFDVI
                     YMLEYLEGKAVANLETNQKYELLRKIENKFDLDQDGNNVYATNVVRRLTMDEVNKLNS
                     FDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFELL
                     AAKGYKEGMVPYISNQYEKDAKAAGSKINSYGKEVGLVTDELVLEKVFNGQYKTWTQF
                     KKDMYKEREKQFSKLNRVNFINPNNPLSRQRNVSVTDIGVLERMIVEAVRDDAQDDVA
                     KFYPETNSRVLKLKKAIYKAYLDQTNDFRSSIFENKK"
BASE COUNT         6625 a         4386 c         4353 g         7178 t
ORIGIN      
        1 tcaaatcgta tatatagtcg atttattaaa tctttagata aactgtaaaa agtggtttcc
       61 atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcggcta tggaacactc
      121 gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca
      181 gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca
      241 ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta
      301 tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc
      361 accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca
      421 tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc
      481 tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat
      541 tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg
      601 taagaagaag gcattagtta ccaatcctca tcacttgatt atcgaatcag cccatccaag
      661 tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaagg ccaatgcatt
      721 cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca
      781 gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa
      841 gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg
      901 agagacgccc caggaatgcg cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa
      961 gccagttcta aaaggtgtca tcacttttcc tgaatttaca ccagatttag actggtacac
     1021 ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct
     1081 agaatgggtt ccctatgatg aggttttgag caagccgact tgggaaggtg accacacctt
     1141 tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga
     1201 taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat
     1261 caaaaatggt cgtgtaatgg atcccaagtc tggtttggat caagtttgtg atgtcttagt
     1321 tcaagatggg aaaattatca aaattgcgtc tgagatcacg gaagaaggag cagaaacgat
     1381 tgatgctact ggtcttgtgg ttgctcctgg cttggtcgat attcatgttc atttccgtga
     1441 acctggtcaa acacataaag aagacattca tactggtgcc ctagcagccg ctgcaggtgg
     1501 ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt
     1561 gcaagcagtt ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat
     1621 tactaaaaac tttaatggta aaaacttgac tgactttaag gcactcttag aagctggtgc
     1681 ggttggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat
     1741 ggaggaagcc aaaaaactca atacctttat cagccttcat gaggaagatc caggtttgaa
     1801 cggtgttctt ggctttaatg aaaatattgc tagagaacat ttccatatct gcggtgctac
     1861 tggggtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc
     1921 ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca
     1981 ggggttaggt gcagaagtca cagcagaagt agcgccacag catttctcta agacagaagc
     2041 acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga
     2101 ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca
     2161 cgcgcctcat catgtagatg aaaaaaatgt tgaggatatt accaaagcgc catctggtat
     2221 gactggctta gaaacatccc tgtctctcag cttgacctat ttagtagaag ctggtgagtt
     2281 gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttga
     2341 agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga
     2401 ccgctttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac
     2461 cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata
     2521 ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg
     2581 gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg
     2641 accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg
     2701 cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc
     2761 tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt
     2821 ttacgagaga agttagtatt atttttaaaa attttcttcc caatcctgat ctaccaattt
     2881 gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac
     2941 ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg
     3001 attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggcaa aaaggaagaa
     3061 gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg
     3121 gggatggtac ttttcttggc accaataatc ttgaatcata ttgggttaga agcagcagta
     3181 gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc
     3241 tttagcgtca ttcgttcctt gctggattcg ctgggcttga ccaaactgtc catgtacctc
     3301 atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt
     3361 ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc
     3421 ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt
     3481 gagaaacgaa ttccacttaa tatggataac attaaggaag gagttcgttt aggtctgcct
     3541 attgggggaa ctgtcttcgc ggaagtggct atcttttcag tggttggctt gattatggct
     3601 aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg
     3661 tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga
     3721 gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac tgctctcatt
     3781 tttgcggcct tcaccctaac cttcctttac atttttaggg gaaatgtggc cagtctttat
     3841 ggtaacgacc caaaatttat cgatttgaca gcgcgttttt taacttatag tcttttcttc
     3901 cagttagcag atacctttgc ggcaccgctt cagggaattt tgcgggggta taaggataca
     3961 gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatccc tgtggctacg
     4021 ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt
     4081 ttgattgtga gtggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa
     4141 tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tattcttgac aagaaaatcc
     4201 cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca
     4261 gtatttgcca aaagcggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg
     4321 tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc
     4381 atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt
     4441 tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg
     4501 attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga cctcaacgga
     4561 atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg
     4621 catatcgctg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg
     4681 gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc
     4741 tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct
     4801 tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg
     4861 gatatcaaga aaatgaccaa tatagaacat atccatcaac gtagcgccgc ttatggaatt
     4921 cctggaatgt tcatcgaaga tggtaacaat gtcatcgatg tctatgaagg atttcagaaa
     4981 gctgtggacc atgttcgcag tggcaatggt tcagtcttga ttgaaagtgt aacttatcgc
     5041 tggctcggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg
     5101 tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca
     5161 agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt
     5221 aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca
     5281 gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc
     5341 cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagatgtc
     5401 ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt tggtccagaa
     5461 cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagcagcagc aggagcagcc
     5521 atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg
     5581 gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt
     5641 ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa
     5701 tctctagagt cttggtttac tcacattcca ggacttaagg ttgtggcacc tggaacacct
     5761 gcggacatga aaggcctgct taagtcttct atccgtgata acaacccagt tattatactt
     5821 gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt
     5881 ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt tacttatgga
     5941 aaaatgcttc gccgtgtggt tcaagctgct gaagaattag cagaagaaga aatttcagtt
     6001 gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg
     6061 aagaagactg gtaaggttat tctggtcaac gatgcccaca aaacaagtgg ctatatcggt
     6121 gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc accaatacgc
     6181 cgttgttcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt
     6241 ccaacagttg aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga ctagagttac
     6301 ataatataag ttatgtaact aaaataaagc tgacgagaaa ctttgtatct tttaggtgca
     6361 gagctcttcg tcattaatat cttatattcg agcacgggct aaaagctcgg aaaaaagata
     6421 aatctccttg gcttcatcga agccatcgtc gatttcctat ttttcagtcg cttttgacgc
     6481 cctttgtatc ataaatagaa ttggagaggt catggctgat gacaagctaa gagcgactcc
     6541 tgcagctaga aagttagcgg atgatttagg gataaacctc tacgacgttt ctggctcagg
     6601 tgcaaacggt cgtgtccaca aagaagacgt ggaaacttat aaagacacaa acgtggttcg
     6661 catttcgcca cttgcaaaac gaattgccct cgaacataac attgcttggc aggaaatcca
     6721 aggaaccggt catcgtggta aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa
     6781 tatcgaaaac gatagcatca aatctcctgc tcagattgaa aaagtggaag aagtccctga
     6841 taacgtaaca ccatatggtg aaatcgagcg tattccaatg acaccaatgc gtaaggttat
     6901 tgcccaacgc atggttgaat cttacttgac tgcgccaacc ttcaccctca actatgaagt
     6961 tgatatgact gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca tggaagcaac
     7021 tgggaagaag actactgtaa cagaccttct ttcgcttgca gttgttaaga ctcttatgaa
     7081 acacccatac atcaacgctt cattgacaga agatggcaag actattatca ctcacaacta
     7141 tgtcaatctt gccatggcag ttgggatgga taatggattg atgacacctg ttgtttacaa
     7201 tgctgagaag atgagtcttt cagaactggt ggtagccttt aaggatgtta ttggccgtac
     7261 cttggatggt aaattggctc caagtgagtt acaaaattca acattcacaa tcagtaattt
     7321 gggaatgttt ggtgttcagt cctttggtcc gattattaac caacccaact cagctatcct
     7381 tggtgtcagt tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc
     7441 aatcatgagt ttaggattaa ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa
     7501 gtttatgaag gacttgaaag agttgattga aacgccaatc tcaatgttaa tttaagagca
     7561 agagtattca tttttaagat atagataaag gaaggaagac atggccttag aaataattat
     7621 gccaaaagcc ggcgtggata tgacagaagg acaaatcgtc caatggaata aaaaagtcgg
     7681 agaatttgta aaagaaggag aaatcctttt ggaaatcatg actgataaag tcagcatgga
     7741 attggaagcc gaagaagatg ggtacttgat tgccattctc aaaggagatg gtgaaactgt
     7801 ccctgtaacg gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc caacagctgg
     7861 agcagcatcg ccagaagcta gccctgtacc tgtagcaagt acctcaaacg atgatggtaa
     7921 gagcgatgat gcttttgata tcgttgtgat tggtggaggt cctgctggtt atgttgcagc
     7981 cattaaagct gcccaactcg gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg
     8041 aacctgctta aaccgtggat gtattccaac caagacctac cttcatagcg ctgaaattat
     8101 tgaaaatatc ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta acttcactgt
     8161 tgatatggaa aaacttttag aaactaaatc taaagttgtt aatactcttg ttggtggtgt
     8221 tgcaggactt cttcgtagct acggagttgc tgttcataaa ggaattggta caatcactaa
     8281 agacaagaac gtcttggtaa atggttctga attgcttgaa accaagaaaa tcattcttgc
     8341 tggtggttca aaagtcagca agatcaacgt ccctggtatg gaatctccac ttgtcatgac
     8401 tagtgatgac attcttgaaa tgaacgaagt gccagaaagc cttgttatca tcggtggtgg
     8461 agttgtcggt atcgaactcg gtcaggcctt catgacattt ggttcaaaag tgactgttat
     8521 cgaaatgatg gaccgtatag ttccagctat ggatgtggaa gtttctaaga accttcgctt
     8581 gatccttgag cgtaaaggaa tgaccatctt gactggtact aaactgcaag aaatcattga
     8641 ggaaaatggt caacttcgta tcaaggttga aggaaaagac gatatcatcg caagcaaagc
     8701 tcttctttca attggtcgta tgccagacct tgaaggtatt ggagaggttg agtttgaatt
     8761 ggatcgtggt tgtatcaagg tcaacgaata catggaaact tcagttccag gcatttatgc
     8821 accaggtgac atcaacggta ctaagatgtt ggctcacgca gctttccgca tgggtgaagt
     8881 ttccgctgaa aatgccctta aaggaaatca tgcagttgcc aaattgaatt tgactcctgc
     8941 agccatctac actcttcctg aagtagcagc agtaggtttg acagaagaac aagcccgtga
     9001 gaaatacgat gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc
     9061 tgacgcagct caaggtttcg taaaagttat cgctgataag aaatacggag aaatccttgg
     9121 tgtacacatt attggtcctg cagccgcaga attaataaac gaagcatcaa gcatcatcga
     9181 aatggaaatc actgttgagg aaatgctgaa gaccatccac gggcacccaa cttactctga
     9241 agtgatgtac gaagcgtttg cagatgttct aggaatggcc atccattcac ctaagaaaaa
     9301 ataaaacgaa gatagattag actggaaggt tatttccagt ttctatcata taaagtaaag
     9361 ggatatcatg aaatacatta tcaatcattc aaatgacact gcttttaata ttgccttgga
     9421 agaatacgcc tttaaacacc ttttggatga ggatcaaatc ttcctacttt ggattaacaa
     9481 gccatctatc attgttggtc gtcaccagaa cactattgaa gaaatcaacc gtgattatgt
     9541 tcgcgaaaat ggtattgagg tagttcgccg tattagtggt ggtggagctg tttaccacga
     9601 tttaaataac ctcaactaca cgatcatctc caaagaagat gaaaataagg catttgactt
     9661 caagagcttc tcaactccgg ttatcaatac cttggctcaa ctcggggtta aagctgagtt
     9721 cacaggtcgt aatgaccttg agattgatgg taagaagttc tgtggcaatg cccaagccta
     9781 tatcaacggc cgtatcatgc accacggttg cttgctcttt gacgttgatt tgtcagtcct
     9841 cgcaaatgcc cttaaggttt caaaagataa atttgaatca aaaggtgtga aatccgtccg
     9901 tgcccgtgta accaatatta tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg
     9961 tgatttactc ttggaataca tgaaaaaaga gtacccagag atgactgaat acgtcttttc
    10021 agaagaagaa ttggccgaaa tcaatcgcat caaggatact aagtttggaa cttgggactg
    10081 gaactatggt aaatcacctg aatttaacgt ccgtcgtgga accaaattca ctagtggtaa
    10141 ggttgaagtc tttgctaacg ttactgaatc aaaaatccaa gacatcaaga tttatggtga
    10201 cttctttggt attgaagacg ttgctgcagt agaagctgtc cttcgtgggg tgaaatacga
    10261 acgcgaagat gttcttaagg cgctaaaaac cattgatatc acacgctact tcgctggtat
    10321 tagccgtgaa gaaatcgctg aagcggtagt tggataaatc aaaaagaagt tggccaacta
    10381 accaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat cataaactat
    10441 ccagagcatt cttttgttca tcactaacaa tatgggtata gaggtcagtg acttgtgtgc
    10501 tagcatgtcc tagttggtga ctgactaaaa cttgtgattt agtcgcatca tagagcctag
    10561 ttgctagtgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt
    10621 tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag
    10681 ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat
    10741 aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgccacctt
    10801 ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct agattaacag
    10861 cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt
    10921 tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga
    10981 tataagttag aaaaccttct gtttcatcac ctagaaagag tttttgcttg atattttcag
    11041 ctctggcagc aagggtttct ttctttttct tggttgaaac ttttttcatt acattacgat
    11101 agaaataagg ttccccctga tcgttttcaa cctcctcggt tagatacttg taaagactag
    11161 aaagtgctga taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag
    11221 cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca
    11281 tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact
    11341 ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac
    11401 tgtagggcac agccagttta gattggtagt attccagaac ataccagggc atgagttgtt
    11461 ttagtttgtc gattcgttcc agtaaaatct cacgtttcat gtattttctc cataattaag
    11521 tatactagta gtatagcata gacttgtaca tttttcaaga aaattatagt ttttcagaaa
    11581 gatgttatag gagtttttca aagtgataaa aagacttaga cctacaaaca aaacagaata
    11641 aggaaaataa taaaaatctc acccactaaa cttctgttaa tactacatag ctagaaattg
    11701 gtttgattgt cctgattgtt ttatcctatt tctatttcat ttcactatat aattgctatt
    11761 gttttctttt tcatgatttt aatcttactg tacagatttg atacagtaaa ctcctttcta
    11821 gctttatact ttatcatttc taacttaatt atagtcttat ttttaataaa gttcaattat
    11881 ttatatgtaa aattcctcat cagtaaaaaa taaccgatct catttctgag aatcggtttt
    11941 ctaaataaat caagccgaat aaatcaagcc gatcatttac ataacataaa ttatgtaaat
    12001 gatcgtacta caacaacaaa tctttgactt ttccaatttc actttttgga ataaccaggt
    12061 gaatcatatc acccagatac attctggttg agccgttaac tgtttggctc ttgccattat
    12121 ggacttgagt tgtgatgagg acgttgtgtg gtaagttgag ttcatgaact tgtttcccag
    12181 caattttatc agaaactggt atttcgataa gtgtaacttc tccttcgcta gatacttctt
    12241 ctggaagcat tttttccagc atggcttcat agactggcgt acctttgagc aaatccatga
    12301 taatataaga aacaagagtg acaagaccaa gtggcatgag gttgcgaata tctcctacca
    12361 tctcagttac gaggatcata gcagttaagg gagcttttga tatggctcca aaatagccac
    12421 tcattcctag aatgacaaat atagggaatt gctcttgact gacaagtcca agattgacac
    12481 agataacacc aactaaggca ccaagcaaag aaccaagagc taaaatgggg aggaaaattc
    12541 ctcctggcag tccacttcca tagctaatca tactccaaat aaagcggatt aaaaagtaag
    12601 ctaataaaac ttggaaacta aaattttgtt cagttaaaga aaggacaagc tgatttccgc
    12661 caccaatgat ttgaggtaag aagattccga ctggtatgat aaggataaaa gccaagatgg
    12721 gataataagc cctatccaaa tggatttttt gaccaatcaa gtcataaact cttccaacgt
    12781 ttaatacagc tttctcatag agaaaacctg aaaatccaag gaaaattccc atgacgagat
    12841 atatccaata ctgatctagg gtcatgggag gaatgttatc tggcatatcc aatactggtg
    12901 tcaaaccgaa catgagtaga gacacaaagt ttgctacgat gctggctgct agagttgaga
    12961 cccagaaaaa gcgcgaaaaa tggtgataga cttcttctac aacaaagaga agtgctgcaa
    13021 taggagcatt aaaggctgcg gctaaacctg ctgcagctcc actggcaatc aaggaacgtt
    13081 cctctactgg actggatttg agccacttgg caattccttt accaccaact gctccaagtt
    13141 gaatgctggg tccctctcga cccagcatga gtccactggc aatagcaaga atacctagca
    13201 catatttttt ccaaagaatg ccccaccagt tgagggacat gaggcctttc agttcggctt
    13261 cgacttgagg aattcctgag cctttaatat ctttttctga ccgtgttagt ttggcactga
    13321 gccaacagat gagtatataa aacaaaacca gtacaaaaag attgcgcact aagtaccctt
    13381 gatcttgata aactccttgt atcaggtgga agcccttttc aattaagaaa cgaaaggatc
    13441 cgacgataat tccaacgatg aggccgacaa tgattcctcg accaacttgg gatagtatag
    13501 tgctggatgc aaaggcgaat tctttcttag aacggactat ttccgactgt tcctccatgg
    13561 tatttccttt caattaattt tcttttttac ctaaaaccag tgatttaacg ggttcaaagc
    13621 tggttcggtg aattggggta actcctagtt ttgtgaggcc ttccagatgt ttagctgtgc
    13681 catatcctgc attagtagcg aaatcatagc cagggaactg ctgatcgtat tccttcatca
    13741 attcatcacg tgttaccttg gctactatag atgctgctgc gatagagagg gagttggcat
    13801 ctcctttgat aatggaggtt tgtgaaatgg gcaagtccag tttcatggca tcaatcaaaa
    13861 ggtgctctgg ttgagggctg agctgggaga ttgcttcttg catggctagt ttggttgctt
    13921 catagatgtt gacttggtcg atgacctgat tatctatgat accaattcca atcgacaagg
    13981 cttggtcttg aacggcttgg aaaatctcca gatgtttctt tttaggaatt ttcttgctgt
    14041 cgttgagacc tttaatctta caatttttag gtaaaatgac ggccgcagcg actacaggac
    14101 cagcaagagg accacgacca acctcatcaa tacctacaat taaggtcaat ccttgcttat
    14161 aaagttcttt ttcataagaa agcatggatt ccaagcgcaa attttcatct aattcagctt
    14221 gaatggctct tttacgcttg ctgatttcct tttgaactcc tgagcgatta tccttttcaa
    14281 gctctaaaaa aatagggctt tctaactcct tgactgtcac aaggagttct ttgatttctt
    14341 taatcgttgc catcgaggtc ttccaatgta tctaaggtat agttaccgag tttgccatca
    14401 cggacttcct tcacgaagag actgtaaaaa cggtcatagt catcacggaa accgagggcg
    14461 cgggtcatat ccataataat cacaggcgct tcttcttcaa ttttcatttg tttgaagcgt
    14521 tcagccagct tttctggata atgttctttg aaataattga taccaaaaat ggtaacctca
    14581 tccataggaa gcaactgatc cttgatagct ccagtcaatg ccaacttaag tgcaacagtt
    14641 tcatcctcaa acttaggcca gagaatcccc ggtgtatcca agatttccag atctttattg
    14701 gttttaagcc attgttgacc ttttgtgacc cctggcttgt ttccaacaac agcaatcttt
    14761 ttaccagcca aacggttcat cagagtggat ttaccagcgt ttggaatccc gataatcatg
    14821 gtacgcaagg tttcaatctg aatcccacgt tctttctggc gagcaatctt atcagccatg
    14881 agcttcttgg ccgcatctgt tacaactttt acagtcactt gctctttgga gttgatagct
    14941 agcgtctgga tttcttgtga ttcaaaatac tgacaccatt ccttggtcat tgctggatca
    15001 gccaagtcgg ccttgtttaa aatcaagagt tttggtttat caccaacaat cttggtcaac
    15061 ataggatttt gactagatag aggcaagcgt gcatctacta aaatcgtcac aaaatcaaca
    15121 aattttaaat tttcctgcac ctgtcgacgc gctttagaca tgtgaccagg aaaccattga
    15181 atagtagcca ttgagttttt tcctttcgta gctctgaagc tgttaatcta gaactaagag
    15241 atctcaatct aaaaatgaat gatgtccaaa cagttcttgt tttatgatat aaaaatctac
    15301 tttatattat atcatgcctt ctttattttg tccgatgata gccttttacc ctatctttta
    15361 ccctatatag aaaaaagcca tcaaatgatg acttttcaga gggagcaaaa aactgtcctc
    15421 tttatatttt aaacatttaa atgtcttctt taaacagttt attaaagaaa ccgtctgtgt
    15481 ttttaagaag ggctttgaat actttggatt tcaagtctac tgtatttttg aaatgatctt
    15541 taattttcgg atctgacata ccatcaatat ctttttgaac agcttcagca aataaagttt
    15601 tcaactgagc ataatttgta atttgacgac catcaatttc aatagcagta aatccttttt
    15661 ctgcttttga cttaacatct ttgaagtatt gtttcttcca ctcttcaaga ttattgaatt
    15721 tatccttaga tactttcttg ataatgaaat catcacccaa taatttttta ttggttttgt
    15781 cagcttcgcc ttgatatttg ctagatgcat aactaatgaa tccattttca taaccaaaat
    15841 agccccacat acggaaagta ttatgcttga atgatgcagc tccaggtgct ccttggctag
    15901 tattaccacc atagataccg gtcattatat taatatttac gtaagcacta tcaaaatctt
    15961 ctggattata tgttctgtca ctaggagcgc catgttttgt catcaaatta ttgttgacta
    16021 aatcatcaat gttgttgata acaattttct tcttctcatc ttcagttaat tcacgaactt
    16081 tatcaaattg atgtagctct ccatttttgc gatattgtct atccattttc ttgaaccatc
    16141 gactaatatt accatgtaat ttagggataa cagcatcagc ctcaagatgg tctaacatca
    16201 taagagcatc attataattt ctcatataac ggtcgatatc ttcacgagtt ttcaatttat
    16261 ctggatcata attataccat tggtcaccgt cattttcacg atgataagcc atgttaagac
    16321 caagagcacc atattcaccg ttaccagatt tatcaggtgt ctgcaacata ccttgcgcat
    16381 aggcttcaac gtctgtacct tgacggtgtc tatgcccacc gaagtaaagc attctatcgt
    16441 ttacgtgtgt tgtttcgtga gtaaaggctg aaataccaaa cggactaatc atatttgttc
    16501 ccatgaaata aacttggtca ttattattgg gatcttggaa aatagatgcc atagctccca
    16561 tgtaccaatt tgtagtatga taacgccaag taggtccata taattcacga ataggtgcaa
    16621 ttggtttatt attcttatca taacccatac gatttacacc ttcgacgtta tgatagtttt
    16681 ggttatccca aacaggtgtt ggaaccctat tttgactctt gagtaattgg tcacgtacgc
    16741 ttggcaatgc taaacgcgac cagaagtcaa gataagtttg ttgtgcgtga gcaacttctt
    16801 taattttatc tttaaatgct tctcgttcag cttctgtata cttaccatat ttttcaaaag
    16861 agctataagc cattgtattg taagtcgaaa tcaagaacat atgtgcattc ttaagagtta
    16921 atagaggtag gatcatacga ttatgaacac cattattcaa accatcaaat gcacgatgtc
    16981 gtttattaac aaaatctggg ttcgttgttt taggctccac aatgtatacg ttcttagccg
    17041 catggataaa ccaatcattt aaatcagtat cgttagtgaa gagacgcatg ttgtaatcta
    17101 agaagccatg taattcagac ttaccaatag ttccaccaat catatcacga taagcatcca
    17161 aagttctgtc acccttgata tttcgctcac ttgatccaat tcgaatcaag aagtcaagaa
    17221 ggtcaactga cttaccatag aaatcaggtt taaacatcat caagtttttg atagtcatat
    17281 ccccatactt tatatcatag taacgattaa ggtaagtaag agccatcacg attttagctt
    17341 tattttcatc caccttctta acaagtgctt tcatagctgc ttcgtcacta tttaattgat
    17401 ggtcagcatt ttcaatcaaa gatttgacca atttatcaag attagctttc gtttcagaaa
    17461 aactttcttc gaaataaagg tctcggatat aaccattctt acgctcatcc gaattagcat
    17521 taggatctct agatgtatct cgtttatcca tcaaagcacg gacttcggga gaaattaatt
    17581 caacagttgc taacctatct ttaatgtctt taatcaattg atcacgattt ttatcaacca
    17641 tgtttggtgt ataaacaatg tcatctaatc catcgatact atactcacga acttgcgcta
    17701 ctttagactc tttttgatga acagctttga tttctttagt cttatctgca tagtgaatca
    17761 tcacatgatc aatatctgat aaatcggtca cgaattgacc atccttcata cccgtaacag
    17821 aaaggacttc tttcttagct aagtttgaat cttctgcaag tttgttacct tgattgacaa
    17881 tccattcttt gttataaaat ggttgcagtt tctcaatatt acgataagcc agatctcgat
    17941 ctactttata gtcttgggtt gacttatatt catcttctct tctggttaaa cgatttaagc
    18001 gattgaccac aggttcattg atttcgtatt tatctgcggt aattcctgta gcttcaattt
    18061 tagattttgc ctcttcctca gaaataggtc tgatacgatt tttatctttt gaacgctggt
    18121 agctagaatg cccatcacta acacctatta caacataatt tcgtcttaca ttatctcctg
    18181 tccagtagcc atcatcataa tcaatatcac tagaaccata gaaaatttca ccattaggta
    18241 ccttcatcat ggaaactgaa tcttcgacag aaccgtggtg cttcatgctt cctacaacac
    18301 caccactttc aatcgcctca gttacttgaa ttgttccctt agcaatagat tttttgattg
    18361 ctccttcctg acgaacagta ttgttatttc cttcattttg tgtccaataa gcaatgcccg
    18421 cagccttggc tttcttgcca ataagatttg cgttaacata cgcgcgttcg acgagtcctt
    18481 tccagttctc accaacgata ccagtcaaga attgtccacc atcgccgaca gaagttacgt
    18541 taccgataaa ggccacattt ctgagtgtac cttggttatc aatcttatca ataaatccag
    18601 atacccaatc tttacctact atattacctt taaccttaac attttcaatg gtagttccac
    18661 ctttaataat attcgctaca gctgcaactt ggttcgccca tggcatattt atgtcaacat
    18721 taccaagatt aatattctta atcgttccac caataacatt gccaaataac ggacgtgaca
    18781 agttatgaat ggtatagtga ttatcaccat cactcaagag cttacctttg aaatctttcg
    18841 taacatatga tttaccaaat gctgatacat ttgtggcatt aaggtcagca cccaatttaa
    18901 actcgtcatt tggatgttct tgcatatctc tcacaagttc attgaaattg taatatacat
    18961 tattgacttt tggaactggt ttttcaatgt aatgaatgta ttcatttcta gtcttagatg
    19021 gatcgacatg ttgaattaaa tcttgagcgc ttgctgtaat tttataaagt tctttttctt
    19081 tttcagttac taactcaatc ttatcaactg ctaaacgagt tactttatta tcacgactag
    19141 tgatttttaa gtacattttc ttcacatctt catcagaagg tttttcgctc atgaaatcac
    19201 taggtatttc agtaccatca tcatttacct tcactaaatt agtagatgaa atatttttaa
    19261 tttcgacctt tttcaactcc aaacgcaaag ttttttcatc cagtttagac gtttcagaac
    19321 cttgaccacg atcataaatc attgttgttg caatcttata atctttaaac aaatccaaat
    19381 tttgtacagc gtcagttaat ttttctttag ataaatcaac ctttttaact actgtatcac
    19441 catctttaat ttcagctata atacttgata tttcagcatt atctttatta tcaagctcat
    19501 aatttaagtt ggcagaacga ttcatagcat cttctgttac tttggtcaag gtcaaaacgg
    19561 gaactgtttt ttcttttgga ttttcttttg taccttttac aagaatttta ggtttcattt
    19621 ctttcaaaat tgttaccgtt tcaactggtt cactaatttt tttgccatgt aactcttcat
    19681 agctagtaac aatttgacgt tcgccatcct caccaacttc tttaacagaa tcatcgccta
    19741 taaatttgct aggatcagat tcttctatag tggttttagg aatagtctct gtacgaatat
    19801 cggtatgtaa agaaggcaac tcttctcttt ctgatgcaac ttctgaaact gtagatattg
    19861 gttcagtata ctctggaatg tcgttaacag gtggttcaat caagtttcca ttttcatcca
    19921 ctcctgttgt acctactggt tcagtgtatg ctagtttctc atgaacttca ggctcaacaa
    19981 ggtttgcacc tattggttgc gtatagtcag gcttctcatg aacttctggt tcgcctttgt
    20041 cagtcacaac agcttctggt aatgtcggtt gtacttccgg ttcgcctttg tcagtcacaa
    20101 cagcttcggg taaggctggt tgaacctccg gttccccttt ctctgttaca actttgggtt
    20161 gctcaactgg cgaaacagtt gatgctggag aaaccgacga aacagtttta tcatcaagct
    20221 ccaagtaacc aacatatctg taaccagaaa tttgcaacac accatcacgt ccagactcat
    20281 ggatgttagc attcaaatta agtgctgaag cagttgatag tgtaactaaa cctgtcgccc
    20341 ctacaatcaa aaatgtagct atttttttat ttctattatc ttttgtgata atcacaataa
    20401 gactcccgat agctaacaaa cccaatgcag tcataataga ttgagaactg cctgtgtttg
    20461 gtagtgcgtc tttttcataa tccaaagcat atgactcttt ggattcatca ggtctacctt
    20521 gtttgagttg atcacgttca gtttgtgtca aactactata atctaagtaa tgataagtcg
    20581 atgcaccaat aactgacggt gcaaataaaa gactccccaa gaataccgaa ccaacaatac
    20641 cctttatttt ccgaatggaa aatttatctt tttttaataa tgacaattct aatcctccac
    20701 attcactttt tatttcctaa tagtaaacac tattttttat tctcaaaaat tgaacttcta
    20761 aaatcatttg tttggtcaag ataagcttta tatattgctt ttttcagttt aagaactcta
    20821 ctatttgttt ctgggtaaaa ttttgctacg tcatcttgcg catcatctct cactgcttcg
    20881 acaatcattc tctctagtac acctatatcc gtaaccgata catttcgttg acgactcaat
    20941 ggattattag gattaataaa gttaactcta tttagtttac tgaattgttt ttctctttcc
    21001 ttatacatat ccttcttgaa ttgtgtccaa gttttatatt gaccattaaa tactttttca
    21061 agtactaatt catctgtaac taaacctact tctttaccat aagaattaat cttacttccc
    21121 gccgcttttg catctttttc atattgattt gagatataag gtaccatgcc ctctttatat
    21181 ccttttgcag ctaataattc gaatgctata cggcgtccca ttaaatcacc aggagtccct
    21241 ttctctccac taagagctga ataaatcggt gaaaataaat caattgtata ataaccattt
    21301 ctcttatatt cttggtcttt gtaccctctg ctagtaataa tatcattttc aattaaacta
    21361 tcaaaagaat ttaatttatt aacttcatcc atcgttaatc tgcgaacaac atttgtcgcg
    21421 tatacattat taccgtcttg atcaagatca aatttatttt caatttttct tagtaactca
    21481 tatttttgat ttgtttctaa attagctaca gcttttcctt ctaaatattc taacatataa
    21541 attacatcaa acatattatg catataatta tgtaggtctt ctgcactatt aaatcgttga
    21601 gttggatcag ctacttgaag tcttgttgaa ttttctgaat cctcatattt caagacagag
    21661 ttaattgtta ttgttggatc atatggatga tccggagctt gtaataatcc ttttgcataa
    21721 aactcaggtc ctaatccgct tcttcttcca tatcctccaa gataaatctc tctatctgag
    21781 ttatgtgtca tttcatgagt atatgttaca gctccatctt tatccaacat acgatatgcc
    21841 atataataga atgcatctcc ggtagcatat gctccgtgtc cattatgaac aacattattt
    21901 cccgcaggtc caaagaagta ttttatagct ggatgatcag tttcaaaagt agcttgatga
    21961 gttactttgt ctttatcttt gtcagtacca aatttgaaag catcatatac tagaatactt
    22021 ctatataatt tttctttatt atcgttatct aatatcttat accaataatc ataatgatct
    22081 ctaaatcgtt tagccgcttc tttggcgtta tcttctacaa atttgtttaa cttttctccc
    22141 ttaggatatt ctgaacttct atatctgtca taggctccaa atccaatagt agaaatattc
    22201 gctatcataa acactgtttt ttcttcaggt aaagttaata gtggtaagac catactttga
    22261 tatttccaag atggattagt taatctatca tataccccaa tagaatattt agttccctct
    22321 tttccttgtt tttctcttcc ctcttcaatt gtagattttt cttctacaat atatgctttt
    22381 gtttgttttt taaaccactc attgttagaa attgttggta agaatacttt tctatatcct
    22441 tctaatgctt taaataaact ttcagttcca taatttttcg ctaataatac attataagta
    22501 attacattat tttttgctaa taaattgtta aatccagatt ta
//
LOCUS       DAVKUR010000033        21715 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKUR010000033 DAVKUR010000000
VERSION     DAVKUR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.033"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..282
                     /locus_tag="VW749_001395"
     CDS             <1..282
                     /locus_tag="VW749_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0175421.1"
                     /translation="KEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(412..1227)
                     /locus_tag="VW749_001396"
     CDS             complement(412..1227)
                     /locus_tag="VW749_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0175422.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(1224..2129)
                     /locus_tag="VW749_001397"
     CDS             complement(1224..2129)
                     /locus_tag="VW749_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0175423.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            2471..2830
                     /locus_tag="VW749_001398"
     CDS             2471..2830
                     /locus_tag="VW749_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0175424.1"
                     /translation="MLHQGDKNSLLESLSIVERQTLKDIEVIIVNQSTEEIASISQQM
                     NLSFNIKIIDENSFAELSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGH
                     FADLVDGVFYFYPFGGG"
     gene            2835..3839
                     /locus_tag="VW749_001399"
     CDS             2835..3839
                     /locus_tag="VW749_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV0175425.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL
                     "
     gene            3941..6070
                     /locus_tag="VW749_001400"
     CDS             3941..6070
                     /locus_tag="VW749_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0175426.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            6057..6506
                     /locus_tag="VW749_001401"
     CDS             6057..6506
                     /locus_tag="VW749_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0175427.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            6564..6836
                     /locus_tag="VW749_001402"
     CDS             6564..6836
                     /locus_tag="VW749_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0175428.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(7190..7381)
                     /locus_tag="VW749_001403"
     CDS             complement(7190..7381)
                     /locus_tag="VW749_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175429.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7809..8567
                     /locus_tag="VW749_001404"
     CDS             7809..8567
                     /locus_tag="VW749_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175430.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8569..10557
                     /locus_tag="VW749_001405"
     CDS             8569..10557
                     /locus_tag="VW749_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175431.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10599..11243)
                     /locus_tag="VW749_001406"
     CDS             complement(10599..11243)
                     /locus_tag="VW749_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0175432.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(11269..12264)
                     /locus_tag="VW749_001407"
     CDS             complement(11269..12264)
                     /locus_tag="VW749_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0175433.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKSAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            12971..14446
                     /locus_tag="VW749_001408"
     CDS             12971..14446
                     /locus_tag="VW749_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0175434.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(14412..15127)
                     /locus_tag="VW749_001409"
                     /pseudo
     CDS             complement(14412..15127)
                     /locus_tag="VW749_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            15382..16242
                     /gene="speE"
                     /locus_tag="VW749_001410"
     CDS             15382..16242
                     /gene="speE"
                     /locus_tag="VW749_001410"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0175435.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            16239..17498
                     /locus_tag="VW749_001411"
     CDS             16239..17498
                     /locus_tag="VW749_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0175436.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            17498..18625
                     /gene="nspC"
                     /locus_tag="VW749_001412"
     CDS             17498..18625
                     /gene="nspC"
                     /locus_tag="VW749_001412"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0175437.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            18622..19707
                     /gene="aguA"
                     /locus_tag="VW749_001413"
     CDS             18622..19707
                     /gene="aguA"
                     /locus_tag="VW749_001413"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0175438.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            19717..20592
                     /gene="aguB"
                     /locus_tag="VW749_001414"
     CDS             19717..20592
                     /gene="aguB"
                     /locus_tag="VW749_001414"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0175439.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(20773..21582)
                     /locus_tag="VW749_001415"
     CDS             complement(20773..21582)
                     /locus_tag="VW749_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0175440.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
BASE COUNT         6540 a         4088 c         4603 g         6484 t
ORIGIN      
        1 aaggaaccgg agaaattttt cggactcatt gaggacaatc ttaagcaggt tcatcctctt
       61 tttcagactg tctttaaaac ctttctaaag gacaaagaga aaatcgtcaa cgcccttcaa
      121 ctacactatt ctaacgccaa attggaagcg accaataatc tcatcaaact tatcaagcgc
      181 aatgcctttg gttttcggaa ctttgaaaac ttcaaaaaac ggatttttat cgccctgaat
      241 atcaaaaaag aaagaacgaa atttgtcctt tctcgagctt agcttttttt caacccacta
      301 cagttgacaa agagccaatc tacaagtcac taattttcat ataacaaaaa aacgaacagg
      361 ctctttttct gttattcaga agagaacttg ttcgttttta tcttgatttt cttaaaaagc
      421 tctatataca tagggatttt ctggtttatc gactttggta aagctgtcga tttccaaggt
      481 tggaaggttt tgtttgagtt ctttatggta gtgattgacc agttttcctt tggctgtaat
      541 ccaggtgttg ttttcatact gccgggtatt gcccttggtc agcaatccat agacaccaga
      601 atctgcgata cagtggataa tgccgaatcg gaacagaaat tgactattgg catgactggg
      661 gtcgttatag acaaagcctg taaactggat tgtcttgccc tcaaattcat ctggatagtc
      721 gtagatagcc tccatgactt ccatatagtt ttcattagtg atctgaatac tatcttggga
      781 taagtattta tccgccgccg ttcgcatttc cttttcatag gctgattttg aaaaataaga
      841 actagtatct ggtttcaaat attggcttgt cgtcccttca cttgtctgaa tagctagatc
      901 cgttccttcc gataggggga aatgataacc tttagcagaa acggtctgag aatccaagct
      961 aacagttggg aaagttaagc cgatgacaag tggaatagcc agaagagaaa tactcgtcat
     1021 cttggccaat cggctgttca gatgactgtg ggttttgact tgcttcatcc agatatacaa
     1081 ttgaacaatt gccaagataa aggaaagcac catggagata taggccagat aggaatagtg
     1141 catgttgatg tactggttta gtttgcccga cagatggagg taaatagtca gttcaaaata
     1201 gccagctaaa actaaaaatc gaatcatagg atgactccaa tcaagagaga ataggctaaa
     1261 acgaccagag tcacaatcgt aatgaagtga ctaataaatc gtgctttcaa gtaatttttc
     1321 atcatgagaa tatttttgat atccagcatt gggccaatga cgagaaaggc cagaactggt
     1381 gccaaaccga aactcgagag tagagaagca cctataaagg catccgcctc actacagagc
     1441 gaaagaagaa aggctaaaag catcaagagc aggatagcaa aaagaggagt cgcactgata
     1501 gaggtcagaa tccgagtcgg aacgtagacc tgtattatag aagcaaagag gcagccaaat
     1561 accaaataac gccccgtatc aaaaaattca tcaatggcct gcacaaagac ttgaaaaact
     1621 ttttttgcag aactcaagta agaaaaatca tgctcatgac aagccagacg attttctttc
     1681 tgaatcggtt cttgccagaa aaatcctaga aaaattccta gtattacagc cacaagaatg
     1741 gaacccagag ctcgtaatag ggcgacatgg aaggagttgc caaaggcaga ataggtcgca
     1801 aaaagaacaa tgggattgat aacaggtgct gtcacaagaa aaggaacggc cgtgtaactt
     1861 ggaacctttt tttccagaaa acgattgatg atggggacga ttccacattc acaagaaggg
     1921 aaaagtatac cgacaaaggt cccaaaaaag attctccccc aacgatttcg agggagaaaa
     1981 tgataaacct tgtcaggtgt gatataaact tcaatcagcc ctgagacaat gcttcctatc
     2041 agaacgaagg gaagggcttc aatgataatg gagagaaaaa tggctccagt ttgaagtaca
     2101 ctagatggga gttgttgaaa agcagtcatc tagtttttct tttctgcttt gacttttttc
     2161 tctttgtcat cagggaaagt aacttgtttc aaatcaggga gtttagcaaa ctcttcaaac
     2221 atcttgtcca agtcgtctcg ttttgtaaat ttgacagcca taggtgtacc tcgattctaa
     2281 attctacctc tattatacta ttattttgcg gaaaagggaa aagttaaaat ttcaaattga
     2341 gtagctaaga gataatatag cttgatatta cctgatatat atcataattg tgctataatt
     2401 aaataaaaag aaaatcatta tcagaaaatt atgggaggta gtcaaactga cttactcaat
     2461 tagtgttgtt ttgttacatc aaggagataa aaatagttta ttagagtctt tgtcaatagt
     2521 ggagagacaa acattaaaag atatagaagt tattattgta aatcaatcta cagaggagat
     2581 agcttccatt agccaacaga tgaatctatc atttaatatt aagattatag atgagaattc
     2641 ttttgctgag ttgtctgata tgattacagg agattatatt acgtttctat cttcaaatga
     2701 ttcattattt gattggacat ttgaaaagat gtatcatgcg ataaaattat ccgattctga
     2761 tgttgttctt ggtcattttg ctgatttggt tgatggagta ttttactttt atccttttgg
     2821 ggggggataa ttggttgaca gaaaatttaa cgaatgttca agttttacaa aagatggatg
     2881 atacagatca tcgaattaga aaacaatatc gctcattatt tggaaaatta ttcaatagta
     2941 agcttttacg aaaaataaat caatttgata taaacaacct tatttggaga ctttatattc
     3001 actctaaaac tgcaacctat attaatttcc cgacatatat ctataaacct gttatagatg
     3061 ctaaacctct aaaagactcc tacaaaatca tattagaaaa ttatgaaaat agaatcaaag
     3121 attgcgccgt cttagaaaac tatgatatag aaagagcgaa aaaacaatat attcaagaat
     3181 tggcaaattt tagtgcttgg ttaaaaaatg acggtgaata tttagattct gatattgttt
     3241 atcataagtt aatagctgca gagaaaggaa ttttcccttt tcttgagctt gatagattag
     3301 attttacgat tataagtaat aattgtgttg gaggattaat ttataaacag cttggttttc
     3361 aatatagaac accttttgtt ggtttattta ttcttcctga tgattattat aaacttacaa
     3421 agcattttcg ttattatatg gaacaagaac ttgttttcga agaggaactt atttcaccga
     3481 gctggactca tgaagtttat cctttggggc acttaggaga tatagatatt cattttctac
     3541 attattctag tattgaagaa gcacgaacta agtgggaaaa aagaaaaaaa cgcataaatt
     3601 ggaataatct ttattttaaa tttgataata aagattcagc tagtgaagaa attttaaata
     3661 agatggataa tcttccttat tctaataaat taattttagt caatcgtcca tataaaaatt
     3721 tgaaaagtca atgtgttatt ccaggtcagg aacatcttcc agaactggct attatgtctg
     3781 atccattaaa tacttttgat atcatggctt ggttaaaaaa aggtggcaat gctctttaag
     3841 tgcaagttat tgcgctgtag catataaatc tatttcctac atatttttta aatgttctac
     3901 gagttaattt gaaacgttta gcttgtggta taatagattt atggataaaa aatatgaaaa
     3961 aatctctcag gatttgggag tgacgttaaa gcaaattgat accgttctaa gtttgacagc
     4021 tgaaggggcg actattccct ttatcgcgcg ttatcgcaag gacatgactg gtagtctgga
     4081 tgaggtggcg attaaggcta ttattgattt ggataaaagt ctgacaaatc tcaatgaccg
     4141 taaggaagct gtcttagcta agattcaaga acaaggtaag ttgaccaagg aattggaaga
     4201 agctatctta gttgccgaaa aattagcaga cgttgaagaa ctctatcttc cttataagga
     4261 aaagcgtcgt accaaggcaa ccattgcccg tgaagctgga ctctttcctc ttgctcgttt
     4321 gattttgcag aatatagttg acttagagaa agaagctgaa aagttcgtct gtgaaggatt
     4381 tgcgactggc aaggaagcct tgaccggtgc agttgatatt ttggtcgaag ccttatcgga
     4441 agatgtgacc ttgcgttcta tgacttatca ggaagtgctg agacactcta aactcacttc
     4501 tcaagccaag gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt atgatttttc
     4561 agagacagtt ggaactatgc aaggctatcg taccttggct ctcaatcgtg gggagaaact
     4621 tggtgtcttg aagatcggtt ttgaacatgc gacggaccgt attcttgcct tctttgctac
     4681 tcgtttcaag gtgaaaaatg cttatattga tgaagttgtt cagcaatccg ttaagaaaaa
     4741 ggtcttgcct gctattgagc gtcgtattcg gacagaatta actgagaaag ctgaagaggg
     4801 agctatccaa cttttttctg acaatctgcg caatctcctc ttggttgctc cactgaaagg
     4861 gcgcgtggtt cttgggtttg acccagcctt tcgtacaggt gccaagctag ctgtcgtgga
     4921 tgcaacagga aaaatgctga caactcaggt tatttatcct gttaaaccag catcagctcg
     4981 tcaaatcgaa gaagccaaga aagatttagc agatttaatt ggtcaatacg gtgtagagat
     5041 tattgccatt ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag cggaagttct
     5101 gaaagatttc cctgaagtca gctatgttat cgttaatgaa agtggtgctt ctgtctattc
     5161 tgccagcgaa cttgctcgtc aggagtttcc agacttgacc gttgaaaaac gctctgccat
     5221 ttctatcgcc cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg atcctaagtc
     5281 aattggtgtc ggtcaatacc aacacgatgt cagtcagaag aaactatctg agagtctgga
     5341 ctttgttgtc gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag ctagcccagc
     5401 tcttctttca cacgtagctg gactcaataa aaccatttct gaaaatatcg tcaaataccg
     5461 tgaggaagag ggaaaaatca cttcacgctc ccaaatcaag aaagttcctc gtttgggggc
     5521 caaggctttt gaacaggctg ctggtttcct ccgtatccct gaaagtagca atatccttga
     5581 taatacagga gttcacccag aaaattacgc tgccgttaag gaactcttca aatgcttgga
     5641 cattaaggat ctgaatgaag aggcccaaag taaactcaag tcgctttcag tcaaggaaat
     5701 ggcgcaagag ttagaccttg gtccagaaac tcttaaagat atcattgcag atcttctcaa
     5761 accaggtcga gatttccgtg attcctttga tgctccagtt ctccgtcaag atgtcctaga
     5821 tatcaaggac ttagtggttg gacaaaagct agaaggagtg gtgcgtaatg ttgttgattt
     5881 cggtgctttt gttgatatcg gaattcatga ggacggtctc atccatattt cccatatgag
     5941 tcgcaagttt atcaaacacc ctagtcaagt ggtggcagtt ggagatttgg tgagcgtttg
     6001 ggttaagaaa attgatactg aacgtgaaaa agttaatctg tctctcctag ctccaaatga
     6061 aactgactga ttacgtcaag caggtttcac tagaagactt cggcagacct tttatccatc
     6121 atgtccagtg gaataggcgt ctacgttcga caggtgggcg atttttcccc aaagatgggc
     6181 atttggattt taatcccaag gtttatcagg aactggggtt ggacgttttt aggaaaattg
     6241 tccgacatga actctgtcat tatcacctct attttcaagg gaaaggctat caacacaagg
     6301 atcgggattt taaggaactg ttgaaagcag tggatggatt acggtttgta ccatccttgc
     6361 ccaatagtaa ctccaagcca atcaagctct atcgttgcca atcctgccag caaacttatc
     6421 agcgtaagcg taggattgat acccaacgct atcgctgtgg actttgtcga ggaaagttgc
     6481 tattagtaaa tcagcctgag gactgatgaa agccgagcct atccgtgata tactagtcta
     6541 acctagcaga aagaggaaat atcatgaaca gtaagtttta taaaatgaga cgaaatcgca
     6601 tgatttcagg agttttagca ggtctgtcag acaagtggaa ctttgatgtt acccttgtac
     6661 gttttctgtt tgccattttt acagtcgcaa actttggact tggggtgatt atctatatca
     6721 tcctagcttc tatcatgcca accaaggaag aaatcgaagc agaaatgtac ggaacaggcc
     6781 cacgtaaacg caaagaagct caagccattg acgataatga aggctggttt tggtgaggtt
     6841 ttacaaaaga tttggaatac gcaaaaagct ttaaatcaat agtctaaact gcttgattta
     6901 aagctttttt acttttatac tcaataaaaa tcaaagtgca aactaggaag ccagccgcag
     6961 gctgtaattt agtcggcaat gtgaagttga tatagtttgc actttgattt ttgaatagta
     7021 ttaataatat ttcgccagct tcatccacaa actatagtgg attggaacta gaataggaca
     7081 cctatacttc taaaaaattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt
     7141 cttatttcat tttactataa aagcagtaat ttaaacgcag ttttttaatc tatttttgct
     7201 gttgagacaa tacatttttg gaaaaatggt ggatgctgat aacaactgat aaccagcaaa
     7261 taacataagc agtgccggta aattctgtac cgataaagtg tgtgtgttca actaagagct
     7321 gaccgatgaa tggagagagc agatagagaa gtccgatgag tatatgttct ttgtgtttca
     7381 ttaaagcgca ccttctttcc ttataggttg aacgacttgc aagtgttaaa ttgaatggta
     7441 tgttatctag gtaaccttac taaaatgtta gttcccgctt cctccttttc aaagtaagcc
     7501 ttttcacact tatattttac aactttaaaa ataggaaatc aaatcatttt ctaagtaatt
     7561 ttgcttatat ttcacccaat cttacaaaaa tgtaagatta aagtctcttt tgtaaggtta
     7621 ggttatggca agcggtcttt ttttgatgta aactagactc ataaagaaca aaggagtaac
     7681 atcatgaaac aaatcttaca taagaaaact agaaaaccaa gtcacaaaga aattgagcgc
     7741 gttcagctgg gatgcactat gatgcaagct acatttcatt tgatgggata ttaagaaagg
     7801 agattctcat gacactttta gatgtaaaac acgttcaaaa aatttataaa acacgttttc
     7861 agggcaacca agtagaagcc ctcaaggata ttcactttac cgtcgaaaag ggtgactacg
     7921 ttgccatcat gggtgagtct ggttctggta aatcaactct tctcaatatt ctagctatgc
     7981 tggataaacc aagtcgtggt caggtttact tgaatggaac tgacaccgca accattaaaa
     8041 attcacaggc ctctagcttc cgtcgtgaaa agttgggctt tgtcttccaa gactttaact
     8101 tgctagatac tctatctgta aaggacaata tcttgcttcc gcttgtcttg tcaagaagac
     8161 ctattacaga gatgatgaag aaattggtgg tgacagctga gaatctggga ataaaccaat
     8221 tacaagagaa gtacccttac gagatttctg gtggtcagaa acagcgtgta gcagtagccc
     8281 gcgccatcat cacagaacct gaaattctcc ttgcggacga accgacagga gctcttgact
     8341 ccaagtcatc tgcagcctta cttgatgtct ttgatgaaat caatgagcgc ggccaaacca
     8401 ttctcatggt aacccactca acagcagcag ctagcagagc taaacgtgta ctctttatca
     8461 aagacggcat tctttacaat caaatctacc gtggagagaa gacagaacgt cagatgttcc
     8521 aagaaatctc tgataccttg actgtcatgg caagcgaggt gaattagtat gtttcgatta
     8581 accaataagt tagcggtatc gaacttgatt aaaaaccgca aactctacta tccttttgcg
     8641 ctggctgttc tcttggcagt cactgtcacc tatctctttt actctctaac cttcaatcct
     8701 aagattgcgg aaatccgtgg aggaacaacc attcaggcta cacttggatt tggtatgttt
     8761 gtcgtcaccc ttgcgtcagc cattatcgtt ctctatgcca atagttttgt catgaagaac
     8821 cgttccaagg aactaggaat ttatggcatg ttgggcttgg agaagcgtca tcttatcagt
     8881 atgaccttta aggagttagt ggtatttggg attctaactg ttggagcggg tatcggtatt
     8941 ggagccttgt ttgacaagtt gattttcgct ttcctactca aactgatgaa attgaaggtg
     9001 gaactggtcg ctaccttcca gatgaaagtt gtcattacag tacttcttgt cttcggtttg
     9061 attttcctag gcctcatgtt cctgaatgcc cttcgaatcg cccgtatgaa tgccctccag
     9121 ctctcacgtg agaaagctag cggagagaaa aaaggtcgct tccttcctct ccaaactatt
     9181 cttggttcca taagtttagg gattggatat tatcttgccc ttacggtaaa agatcctctt
     9241 acagccttaa caaccttctt catagctgtt ttactggtta tctttggtac ttatcttttg
     9301 ttcaatgcag ggattaccgt tttccttcaa atcttaaaga aaaataagaa atactattac
     9361 caacctaata atctcatatc tgtttctaac ttgattttcc gtatgaagaa aaatgcagtt
     9421 ggactagcaa ctatcgctat tttgtcaaca atggttttgg taaccatgtc agcagcgaca
     9481 agcattttca attccgcaga atcctttaaa aaagttctaa atcctcatga ttttggggtt
     9541 tcagggcaaa atgttgaaaa agaagatttg gacaaactct tgagccagtt tgcaagtgac
     9601 aaaggttata agattaaaga gaaagaagtg cttcgttaca gtaactttgg tattgcaaat
     9661 caagaaggaa ccaagttaac tatttttgaa aaaggacaaa accgtgtcca accaaaaaca
     9721 gttttcatgg tatttgacca aaaagattat gaaaatatga ctggtcaaaa actgtctcta
     9781 tcaggaaatg aggtcggtct ctttgccaaa aatgacggac tgaaaggaca gaaagctcta
     9841 actctaaatg atcatcaatt ttctgtcaaa gaagaattta ataaagattt cattgtcaac
     9901 catgttccaa ataagtttaa tatcttgact actgattaca attaccttgt tgttcctgat
     9961 ttacaagcct ttttggatca attcccagat tcggctatct ataatcagtt ttacggtggt
    10021 atgaatgtag atgccagcga agaagaacaa ctcaaggtcg ctgaggagta tgaaaactac
    10081 ctcaatcaat ttaatgctca attagacaca gaaggtagct atgtttatgg tagcactcta
    10141 gcagatgcta gtgctcagat gagtgccctc tttggtggtg tcttctttat cggtattttc
    10201 ctatccatta tctttatggt cggaactgtt ctggtcatct actacaaaca aatttctgaa
    10261 ggctacgaag accgtgaacg ctttattatc ttgcagaaag tcggtttgga ccaaaagcaa
    10321 atcaagcaaa ccatcaacaa acaggtttta actgttttct tccttccttt gctctttgcc
    10381 ttcctacatc tagcctttgc ctaccatatg cttagcctga ttttaaaagt gattggtgta
    10441 ctggatacga ctatgatgtt gattgtgacc ttgtctatct gcgctatctt cctcatcgcc
    10501 tatgtgctga tttttatgat tacttcaaga agttatcgca agattgtgca aatgtaaaaa
    10561 agatacctcg acttcaaaat cgaggtattt cttgtattct aaatgctgaa aagttgttcg
    10621 agcaggaagg taactcccat ggtcaagaga ccaatagcaa ggttccgaat catagctgtt
    10681 ttggttgggg cttttccaag tctagcactt gtgtaaccag tgagaagaag ggccacaccg
    10741 acaataagga cggtagcagg gatgcggtaa tcacttggaa aaatggtcac tgacagcatt
    10801 ggaggcaaac ttctaaggaa aaaggcaacg aagctagaaa tggcagcgtg ccaaggattg
    10861 gtaaattctt catactcaat cccatatttt tcctctacca gagccttgag tggattttta
    10921 agaaagatct tattagtcaa gagttgggca gaagttttga attctccatt ttggatataa
    10981 gaagcataga gggatttttt ggctagttcc ctatcttggt ctagcaagag tttttctcgc
    11041 gaaacggcag cttcctcggt atcttttgga gttgaaacgg atacatattc tccaccagcc
    11101 attgaaaagg caccagctaa gatagccgca aaacctgata aaaagataat ccagatattg
    11161 ctcgtggcac tggcaactcc gataaccaca ccagcaatgg aaataattcc atcgttagca
    11221 tcaagaacac ccgcacgcag gatatttaaa cgacctgcaa aatttgaatc aatttcgtga
    11281 tttgtttctg acgctaaatt tcaagttcaa gttagccatc cagaagtctt ctctgggtga
    11341 cttgtagtcc aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc
    11401 tttgggagtc attttcttga ttcccttagg taaccatcta cgaatgagcc tgttgtgatt
    11461 ctcattagtt cccctttccc aagaggcata ggggtgcgca taatagatgt gctcctcaga
    11521 aaatacatca aacaagcgat tgaattccgt tccattatct gccgtgatgg aaagaatctt
    11581 gtgttgtttt aagatgagtt ttagagcctg attgaccaca tcagcacttt tatttggaat
    11641 caatcggatg atctgatgtc tactctttcg atccgtcaag acaagcaaac agtagttttt
    11701 cgctctcgta agtagaaccg tatcaatctc ataatgccca ttctccaagc gaagattgat
    11761 agcttcagac cgctgttcga tggattgacc agcagattta aagttggtgc tagcctgttt
    11821 cttaagcgct tttccttttc tagggtaaag cagatcctgt ttgcttaacc ccaattttcc
    11881 atgatgaatc caatagtaaa tggttgaaat tcccacgtta acccctttaa ccatcaccat
    11941 catttcaggc gaaaattttt ggttatgata gtggagaatc ttttccttta gttccttggt
    12001 cacgcttgat ttcctgaccg agcgcttgcg attgttttca taagactgtt gagcatagtc
    12061 ggcagaataa acctctttga agcgcccttt tccaagacat tgtcggactg tcccacgctt
    12121 gatttcagtg tggatagttt gaggaacttt tccaagcaga gaggcaattt ctctatttga
    12181 tttcccttct tttttccatc tttcgattaa gcgacggcta tcgattgtca aatgtttggc
    12241 ttttgtagta taattgtctt gcatctctgt gcctttcttg tgtttgtggt tgaacaacaa
    12301 gtataacaca gaggtgtttt cttatgccta caagagctat cagctagttg aaccatctaa
    12361 tttttaggag ggctgggtgg ctaacttcat tatagaactt tcatttacga acatatagta
    12421 aaatgaaaca agaacagaac aaatcgatca ggacagtaaa atctatttct aataatgttt
    12481 tagaagcaga agtgtactat tctagtttca atctactata tttttgtttt ttatcaaaaa
    12541 atactttaca agttcttaaa aacatgatat agtaataaag cttagaaaat gagatgatgt
    12601 tttctagcaa atataaaccc gagtaaaaaa tgcctacgga caggcagggt tgaatgccga
    12661 agcgtggttg aaaagccaca ttattgatag ggttaaaagc ctacttttat aagttgatgt
    12721 taggacactt gtcctaattc ataaattttt agtgtggtga aagcacacgt catcttgtga
    12781 aacgatcaat aaagtacgta atatttgcta ctagagagtt aggaaacatc gggaacagac
    12841 atactcaaca gaaaccaaaa taaacacgtc agaagattgc agagcaggtg aaaacctgct
    12901 cttttttcat gagtcaacct ttagttcctt agttttcata aggtcctaaa aatattgaaa
    12961 ggagtatgtt ttgaaagagt tagatcaaaa ccaagcccca atttatgaag ccttggtgaa
    13021 gttacgcaag aaaaggattg ttccctttga tgttccaggt cacaagcgtg gacggggaaa
    13081 tccagaactt gtcgaactct taggagaaaa atgtgtaggc attgatgtca attcgatgaa
    13141 acccttggat aatttaggcc atcctatttc gattattcgt gatgcagagg agctggctgc
    13201 agatgctttt ggagctagcc atgcctttct aatgattggt ggaacaactt catcggtgca
    13261 gactatgatt ctggcaacct gcaaggcagg agataagatt attctgccac gaaatgtcca
    13321 taaatctgct atcaatgcgt tggttctatg tggtgccatt cccatctata tcgagatgag
    13381 tgtagatcct aagattggta tcgctttagg tcttgaaaat gaccgagtag cacaggccat
    13441 aaaggaccat ccagatgcta aggctatcct aatcaacaat cctacttact acggcatctg
    13501 ttcagaccta aaggggttga cagaaatggc tcatgaagct ggcatgatgg ttttagtaga
    13561 tgaagcccat ggagcgcatt tgcatttcac tggtaaactt ccaatttctg ctatggatgc
    13621 aggagctgat atggcagcag tttccatgca taagtctggt gggagtttga cacaaagttc
    13681 gcttctttta atcggggagc agatgaatcc cgagtacgtt cgtcagatta taaacctgac
    13741 ccagtctaca tctgcctctt acttattgat ggctagtttg gatatttcac gtcgcaactt
    13801 ggcccttcgt ggtaaagagt cgtttgagga agtcattgag ctatccgagt acgctcgtca
    13861 tgaaatcaat gccattggcg gttactatgc ttactcaaaa gagttaatag atggtgtgtc
    13921 ggtctgtgat tttgatgtaa ccaagttgtc agtttacact cagggaatag gcttaacagg
    13981 tatcgaggtt tatgacctct tgcgagacga atacgacatt cagatcgagt ttggtgatat
    14041 cggcaatatc ttggcctata tttccatcgg cgaccgcatc caagacatcg agcgcttggt
    14101 tggtgctctg gctgatatta agagactcta ttcacgagat gggaaggact taatagctgg
    14161 agaatatatt cagcccgagt tggtgctgtc tccacaagaa gccttctatt cagagagaaa
    14221 aagtttgacc ttagatgagt ctgttggaca ggtctgtgga gaatttgtca tgtgctatcc
    14281 tccagggatt cctatcttgg ctcctggtga acgcattaca cgagaaattg tagactatat
    14341 ccaattcgcc aaggaacgtg gttgctccct ccaagggacg gaagatccag aggtcaatca
    14401 tatcaacgtt attaagagaa agacaaacta taagaaaagt caatagtttt atctaaacta
    14461 tttcttattt caatttgatg atttggcgat gattttagag cacggcaaaa agcccttgaa
    14521 ttagaagcgg tcaatcgctt aatttctatc agcttatcaa atcctgcctc aatccttttc
    14581 tgaggattag ggtagcgtgt caagagttgg taggtatatt ctgaatgctt tccaacgatt
    14641 ttatccaact caggaaagat gatatcaaga caacgagtgt attgtacttt ccaatcagac
    14701 tgtttttctt gagacgatga atatgtctag ccagtatttt tagttctact tgccgattat
    14761 cgtgttgaaa ttgttcacga ttggggtcag aaagaagttt aagagcgatg ccatgagcgt
    14821 ctttcttatc cgttttagtc ttgcgaagtg ataatgattt ggcaaattcc ttgatgagca
    14881 aaggattgta ggtgtaaact ttatatcctt gttcatgcag gaagttcagt agattaaagg
    14941 cataatgtcc agtatcttca agagcgatga gacagtcttg gttgagctgt cgaagagaca
    15001 gatctaagag ttcaaaacca gctttattat ttgaaaaagt gagtggttta agaacagttt
    15061 ttccttgaac attcaaggct gtaacatcgt gtttattttt agcgatatca atgcccacat
    15121 aaagcatggg agtacctcca gatgtagtat ttcaagtcta cttggttatc cacgaacttt
    15181 ttgccttgtt accttagacg agataaaacg tctatgcgtt atcaaactca ttaccaattg
    15241 aaacaaaagc tgtggttaga gcctttcgga aatcgtcaag cgattggagg aaatgaacta
    15301 atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
    15361 atataatata aggagaaata gatggattta tggttttctg aagttcatac tccagatgtc
    15421 aaattgtctc tgagaacagc caagcaactt tacgctggaa aaagtgaatg gcaggatatc
    15481 gaagtcttgg atacgccagc ttttgggaaa atactgattt taaatggcca tgtcttgttc
    15541 tcagatgcgg atgatttcgt ctacaatgaa atgaccgttc acgttcccat ggctgtccac
    15601 ccaaatccaa agaaagtatt ggttattggg ggtggtgacg gcggtgttgc ccaagtatta
    15661 accctctatc ctgaactgga gcaaattgat attgtggaac cggatgagat gttggtcgag
    15721 gtctgtcgtg agtatttccc agactttgct gcagggctag atgatcctcg tgttaccatt
    15781 tactaccaaa atgggctacg ctttttgcga aactgcgaag atgattacga tattatcatc
    15841 aacgatgcga cagatccatt tggccatacg gaaggactct ttaccaagga attctacggc
    15901 aatagttatc gagctctgaa ggaagacggc atcatgattt accagcatgg gagtcccttc
    15961 tttgacgagg atgagtcggc ctgccgaagc atgcaccgca aggtcaatca agcctttcca
    16021 atcagtcggg tttatcaggc ccatattcca actagcccag ctggctattg gttgtttgga
    16081 tttgcatcga aaaaatacca ccctgtcaaa gattttgaca aggaaggctg gaaaaaacgc
    16141 cagcttttca cagaatacta cactgcaaac ttacacgtgg gagcctttat gttgcccaag
    16201 tatgttgagg acattttaga agaagaggaa ggaaaaaaat gagtcgttta ctagttattg
    16261 gttgtggggg cgttgcccaa gttgctattt caaagatttg tcaagatagc gaaacattta
    16321 cagagattat gattgctagc cgtaccaagt caaaatgcga tgacttgaaa gcgaagctag
    16381 aaggcaaaac aagtactaaa attgaaactg cagcacttga tgctgacaag gttgaagaag
    16441 tgattgccct gattgaaagc tacaaaccag aagctgtttt gaatgtagct ctgccttatc
    16501 aagatttaac cattatggat gcttgtttgg caacaggtgt tcactatatc gatacagcca
    16561 actacgaagc agaagacaca gaagaccctg agtggcgtgc tatctacgaa aaacgttgta
    16621 aggaacttgg ttttacagcc tactttgact actcatggca gtgggcttat caagagaaat
    16681 tcaaagaagc aggcttgact gctcttcttg gttctggttt tgacccaggt gtaactagtg
    16741 tcttttcagc ttatgccctc aaacactatt ttgatgaaat ccattatatc gacattttag
    16801 actgtaatgg cggtgaccac ggttatccat ttgcaaccaa ctttaatcca gaaattaatc
    16861 tccgtgaggt ttctgcgcca ggttcttact gggaagatgg gaaatgggtc gaagtcgaag
    16921 ctatgtctat caagcgtgag tatgatttcc ctcaagttgg acaaaaagat atgtatctcc
    16981 ttcaccatga agaaatcgaa tcattggcca agaacattcc aggtgtcaaa cgcattcgtt
    17041 tctttatgac ttttggtcaa tcttacttga cgcacatgaa atgtcttgaa aatgttggac
    17101 tccttcgtac ggataccatt aactttaacg gccaagaaat tgttccaatt caatttttga
    17161 aagccttgct tccagatcct gccagtcttg ggccacgtac agtcggaaaa accaatattg
    17221 gatgtatctt tacaggtgtc aaagacggtg tcaaaaagac tatctatatc tacaatgtct
    17281 gcgaccatca ggaatgttac gcagaggttg gttcgcaagc tatttcttat acgacaggag
    17341 ttccagccat gattgggaca aaattagtca tgaacggaac ttggaaacaa gctggagtgt
    17401 ataaccttga ggagttagat ccagatccat tcatggaagc tttgaatgag tatggtttgc
    17461 catgggttgt ggttgaaaat ccacaaatgg tggactaatg aagttagaac aagtaccaac
    17521 accagcctat gttattgact tggccaagtt agaagctaat tgccgcattc tacaatatgt
    17581 acaagaagag gccggttgca aggtcttgct tgcccagaag gcatattccc tctacaaaac
    17641 ttatcccttg attagccagt atctatcagg tacgacagct agtggactct atgaggccaa
    17701 attggcaagg gaagaatttc ctggtgaagt ccatgtattt gcgcctgctt tcaaggatgc
    17761 agacttggag gaattgctag agataatgga ccatatcgtc tttaactcag agagacagtt
    17821 gcgtaaacac ggtccgcgtt gtcgagaggc tggtgtcagt gttggtttgc gcctcaaccc
    17881 tcagtgttca actcaaggag atcacgcgct ctatgaccct tgtgcaccag gttctcgctt
    17941 tggagttact atagacaaga ttccgagtga tttgctagat ttggttgacg gacttcattt
    18001 tcataccctt tgcgagcagg gagcagatga tttacaaaca actttgaaag cagtagaaga
    18061 acagtttggt ccctacttac atgaggtaaa atggctcaat atgggtggtg gtcatcatat
    18121 tacaagagaa ggttacgatg tggatttgct gatttcagaa atcaagcgta tccgaaaaac
    18181 ttacaatctt gaaatctata tcgagcctgg tgaagccatt gcgcttaatg cgggttattt
    18241 agcaactgag gtattagata ttgtagaaaa cggtatggaa atcttggttt tagacgcctc
    18301 tgcgacctgc catatgcctg atgtacttga gatgccctat cgtccacctt tgagaaatgg
    18361 ctttgagtca caggaaaaag cccataccta cagactttct tctaatacct gtctgacggg
    18421 cgatgtgatt ggtgattata gttttgaaaa tccagtccaa atcggagaca gactttattt
    18481 tcaagacatg gccatttatt cttttgtcaa aaataatacc tttaatggta ttggattgcc
    18541 aagtctctat ctcatggacg aacagggaga ctgtagctta ctcaaagctt ttggctatca
    18601 agactttaaa gggagattat catgatggac agtccaaaaa aattaggcta tcacatgcca
    18661 gcagagtacg aaccccatca tggtaccctc atgatatggc cgactcgacc aggatcatgg
    18721 ccttttcaag gaaaggctgc taaaagagca tttactcaga tcatcgagac catagcagaa
    18781 ggggaaagag tctatctttt ggtggagcag gcctatctat ctgaagccca atcctatctt
    18841 ggagacaagg ttgtttattt agacattccc accaatgatg cctgggcgcg tgatactggc
    18901 ccaaccattc tcgtcaatga taaaggtaag aaattagccg tggattgggc ctttaatgct
    18961 tggggaggca cctatgatgg tctttatcaa gattatgaag aggatgacca agtagccagt
    19021 cgttttgctg aggccttgga aaggcctgtc tatgatgcta aaccttttgt actggaagga
    19081 ggcgcaatcc atagcgatgg tcaaggaact attctcgtaa ctgaaagttg cttgcttagt
    19141 cctggtcgca atcctaacct gactaaagag gagattgaaa acacattatt agaaagtctt
    19201 ggtgctgaaa aagttatttg gcttccttat ggtatttatc aggatgaaac caatgaacac
    19261 gtcgataatg ttgctgcctt tgttggtcct gctgagcttg ttttggcttg gacagatgac
    19321 gaaaatgatc cccagtatgc catgtcaaaa gcagatctcg aactcttaga acaggaaaca
    19381 gatgcaaaag gttgtcactt caccattcat aaattgccta tccctgcagt tcgacaagtt
    19441 gtgacagaag aagatttgcc aggctacatc tatgaagaag gagaagaaaa gcgatacgca
    19501 ggtgaacgac tagcagcttc ctacgtaaac ttttatatcg ccaacaaggc tgtcttggtt
    19561 ccacagtttg aggatgtaaa cgaccaagtg gccttagata tcctcagcaa gtgtttccca
    19621 gaccgtaaag ttgtcggaat accagccaga gatattctct taggtggtgg caatatccac
    19681 tgtatcaccc aacaaattcc agaataggag aaaaagatga gaaatgtaag agttgcaacc
    19741 attcagatgc aatgcgctaa ggatgtggca acaaatatcc aaaccgcaga gcgtttagta
    19801 cgtcaggctg ctgagcaagg agcccaaatt attctcttgc ccgagttgtt tgaacatccc
    19861 tatttctgtc aggaacgtca gtatgactac taccagtatg cccaatctgt agcggaaaat
    19921 actgccattc agcattttaa ggtgattgct aaggaactac aagttgtttt accaatcagt
    19981 ttctatgaaa aagatggtaa tgtcttgtat aactctattg ccgtcattga tgcagatggg
    20041 gaagtgctgg gcgtttatcg aaagacccac ataccagatg accattatta tcaagaaaaa
    20101 ttctatttca cgcctggtaa cactggtttc aaggtctgga atactcgcta tgctaagatt
    20161 ggtatcggta tctgttggga tcaatggttc cctgaaacag cgcgctgtct tgcattgaat
    20221 ggtgctgaat tgctctttta tccaacagcc atcggttcag agccgatttt ggatacagat
    20281 agttgtggtc actggcaacg tactatgcaa gggcacgcag cagcgaatat tgttccagtc
    20341 atcgcagcca atcgttatgg tttagaggag gttactccta gtgaggaaaa tggcggacag
    20401 agttccagtc ttgacttcta cggttcctcc tttatgacgg atgaaacagg agctattcta
    20461 gaacgagctg aaagacaaga agaagctgtt ctgttagcta cttataacct agacaaggga
    20521 gcaagtgaac gcctaaactg gggcttgttt cgagatagaa gaccagaaat gtatagacaa
    20581 attacagatt agtgtgggag aaatgagaga ttcattctgc tagactaact tcttattagc
    20641 aactataaga tactatggca tctagtaaat cgatttttat gattcgctat tcttctctat
    20701 tgattagtcc gtattttaaa atattagcaa aaaagcaaat agcagtaact tctgtctatt
    20761 tgcttttctt ttttatagaa tatatttctc aatagcacgc gcaacgccgt cttcttcgtt
    20821 gcttgaggta acggcatccg caagagattt gacataatcg ctggcatttc ccattgcaat
    20881 cccaagccct gcaaactgga gcatttcgat atcgttatta gcatcgccca tggccataat
    20941 ctctgaggaa tcaatcttca aaatctcagc tagtcgtgaa agagcagtag cctttgtcgt
    21001 tccaagtggc attgcttcat aaatgacagg ctgcgaacga actccactga atcgttggca
    21061 aagctcttca gcaaaacgct gctcaaaatc gtctgtttgt tcttttgttc ctaaaaacat
    21121 accttggaac atccggaact ttccactagt cgcttcctca agagaaattt cagtcaggtc
    21181 tgaaaatact agtttagcat cattttcaat aacttgattg ggctttccac cgagaacaaa
    21241 ataatgtgac tcgtcaaaaa gtgtcaactg aacatcactc ttttcagcaa ggtcatagag
    21301 gtattcgatg tcagctggac taagttcttg ccagtcaacc aagccccagt cgctagtctg
    21361 gtgagttgaa caaccgttgt taacaatcac atactcattc tggaggtcga gtcccagttt
    21421 tttgtagtag gggaggacac cgaaaagggg gcgacccgta cagagaacca gtttgacacc
    21481 tttttcaatg gctttgtgaa tagcagtaat gtgagcttgt gggatttcct tggcttcatt
    21541 gaggagggtg ccgtccatat ccaaggctag tagtttaatc ataggtcttc cttctttatc
    21601 ttttgctatt attatagcat attttggaga agaaattgat agaaagcttg agactaattg
    21661 attttatagt ttaagatgtt ttgatgacaa ttcatgattt gaagaggata tttcg
//
LOCUS       DAVKUR010000034        21352 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKUR010000034 DAVKUR010000000
VERSION     DAVKUR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.034"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(429..2156)
                     /gene="ezrA"
                     /locus_tag="VW749_001416"
     CDS             complement(429..2156)
                     /gene="ezrA"
                     /locus_tag="VW749_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0175441.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2238..4184)
                     /gene="gyrB"
                     /locus_tag="VW749_001417"
     CDS             complement(2238..4184)
                     /gene="gyrB"
                     /locus_tag="VW749_001417"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0175442.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVYVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4199..4762)
                     /locus_tag="VW749_001418"
     CDS             complement(4199..4762)
                     /locus_tag="VW749_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0175443.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4847..5401)
                     /locus_tag="VW749_001419"
     CDS             complement(4847..5401)
                     /locus_tag="VW749_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0175444.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5412..6635)
                     /locus_tag="VW749_001420"
     CDS             complement(5412..6635)
                     /locus_tag="VW749_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0175445.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6672..9122)
                     /locus_tag="VW749_001421"
     CDS             complement(6672..9122)
                     /locus_tag="VW749_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0175446.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVVLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9322..10251)
                     /locus_tag="VW749_001422"
     CDS             complement(9322..10251)
                     /locus_tag="VW749_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0175447.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10391..10678
                     /locus_tag="VW749_001423"
     CDS             10391..10678
                     /locus_tag="VW749_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0175448.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10712..12046)
                     /gene="ciaH"
                     /locus_tag="VW749_001424"
     CDS             complement(10712..12046)
                     /gene="ciaH"
                     /locus_tag="VW749_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0175449.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12036..12710)
                     /gene="ciaR"
                     /locus_tag="VW749_001425"
     CDS             complement(12036..12710)
                     /gene="ciaR"
                     /locus_tag="VW749_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0175450.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12819..15365)
                     /locus_tag="VW749_001426"
     CDS             complement(12819..15365)
                     /locus_tag="VW749_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0175451.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15488..15928)
                     /locus_tag="VW749_001427"
     CDS             complement(15488..15928)
                     /locus_tag="VW749_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0175452.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15903..16772)
                     /locus_tag="VW749_001428"
     CDS             complement(15903..16772)
                     /locus_tag="VW749_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0175453.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16814..17542)
                     /locus_tag="VW749_001429"
     CDS             complement(16814..17542)
                     /locus_tag="VW749_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175454.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17550..18029)
                     /locus_tag="VW749_001430"
     CDS             complement(17550..18029)
                     /locus_tag="VW749_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0175455.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18040..18738)
                     /locus_tag="VW749_001431"
     CDS             complement(18040..18738)
                     /locus_tag="VW749_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0175456.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18731..18997)
                     /locus_tag="VW749_001432"
     CDS             complement(18731..18997)
                     /locus_tag="VW749_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0175457.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19063..19989)
                     /locus_tag="VW749_001433"
     CDS             complement(19063..19989)
                     /locus_tag="VW749_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0175458.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20064..20879)
                     /locus_tag="VW749_001434"
                     /pseudo
     CDS             complement(20064..20879)
                     /locus_tag="VW749_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20883..21203)
                     /locus_tag="VW749_001435"
     CDS             complement(20883..21203)
                     /locus_tag="VW749_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0175459.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6462 a         4680 c         3741 g         6469 t
ORIGIN      
        1 atgttttaga ggcctattta ccgtggacta aagttgtaca agaaaaatgc aaataagaaa
       61 tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa tagacttcgt
      121 tattggacgg ttaccaagtt actcaaagta cagatttgaa gctgcagata agactgacga
      181 aatcacttta atactaaatg aaaatcaaaa agcaaactaa gaagctagcc tcaggctgta
      241 cttgagtacg gtaaggcgac gctgacgtga tttgaagaga ttttcgaaga gtataaaaca
      301 ctgttttgag gtggtggata aatcggctgg gtaaaaactc aatctcagga gaaaatgaag
      361 taaatctccc cacaactata gaaaaagatt tgattctgct cctcacacaa taaaatcttt
      421 ttcttttatt aaaaacgaat cgtttcacgt gttttctcat atgaggtaac aaagcgattg
      481 gttacaccag gctctgccac ttccaatgct tgagaaatct tatcaaatga agcgtgataa
      541 tcaaattctt tttcaaaaat atctaaagct tcgttaaatg cttcttgaat gcgttcatca
      601 aatgagcgat agcggttaga atattgcaag agttgctctg tcaaagttgc atattgtaca
      661 atattataag tttccgtttc taaagcttcc atatcattcg ttgcaatttc aagaactcgg
      721 gtaacagatt caatgttaat cattttttgt tctaactcaa ccattaaatc ctcggtatta
      781 ttgcttgccg taaagaataa cttcaagaaa gtttgtggaa tacctggcag attgcgtttt
      841 tccatgtatc gcttgatagt atggagacga ttgacataaa cattggcctt ttgacgtgca
      901 ttaatatcat ctttctcaat ttgtgtcagg cgctcactaa ctgaaatttg ctcatcttca
      961 atatctttta gttgagtttg taaatcctca agattttctt caagaactga ataagcttgg
     1021 ggtggttctt cttgatttga agttacctca acaatagctg cctcaaaact ctctaattct
     1081 gtctgaatac gacgaacatg gcttgcagct gtctcaggaa gtaaataggt cttgttcaaa
     1141 cgtgcaatat cttctcccaa taaagtatta ttctctttca tatgttgaag ataagttgga
     1201 agagttgcaa gtagattttc cactactttc tgagcagcaa tttctcgagt aaaaatatca
     1261 tacaaggcat tgatttcctc ttgtgcctgt ccattctcat attcggcatt atccaattcc
     1321 aactgacgaa tattctcttg gtttttcttg aatgcttcat aaagcaagtg gaaacgcgct
     1381 tcaatatccg tttcaacaaa atgataatta gcatcaatta gtttacgata accggcttcc
     1441 aaatcctgta attgatctgg caattctgta gaaagcgtcg taaccaaggc tggaacacga
     1501 tccacaatat gacttaaggc caaaatgtga ttttctgtat tatccaaaat cactgcggct
     1561 tccacagggt cacccgatga attcaaggtt acaaattgtg aaaattcaga ttggatattt
     1621 tctaattgtt tttcaatttc atccaaggct tgaccatact gttctgaatt ttcagcaact
     1681 ctatgctgaa gttcctcaaa taaatccaaa gcatgaagaa cacgaccact atttttagat
     1741 tcttgcttct ctaagtctgc caaagcattg cgaattgccg caatatcttc ttcaatcaaa
     1801 gtaatttgac tctcaatttg gtcaatttga tgactggcct tgagaaaacg aaatgaatgg
     1861 ttataacctt ctgcttcaaa gagattattt tcaatatcgg caaaagagtt gagagataaa
     1921 tcgacccatt tttgattcca ttcacggaaa gccacttgac tttgtccaat caagtgcata
     1981 ttttttacag cttctacttc atcatttact ggaagattgt atagttcttc ttttctttct
     2041 tctagtgcct ctaatctccc ctcgtttcgc ttacgtagaa agattgccac tacataagcc
     2101 agaactaaaa tgactgcaat tgcaaccatt aaataaatta gttgtccatt agacatatca
     2161 aactcctttt ttacttgaaa caatcgtaac gattatatca tattttttag accaagggaa
     2221 ctacttctcc ctatttttta gacatcaagt gtactataga cagcattttc ttcgataaac
     2281 tcacgacgag gctctactcg atcccccatc aacatatcaa agattttatc tgcttctgca
     2341 gcatcatcta cagaaactct agccatcaag cgatgttcgg gatccatggt tgtttcccac
     2401 agctgatgat cgtccatttc acctagcccc ttataacgct gaatagtcgg tttggtacga
     2461 ccttcactat aacgggctaa agcttcttgg agtttgattt cttgatctgc acccggctgg
     2521 atatattctt taatctcgct tccaaccttg acaccataga ttggtggttg ggcaatataa
     2581 acataaccag cttctaggat tggtttcata taacgataaa tcaaggttaa aagaagggta
     2641 cgaatatggg ctccatcgac atcggcatcg gtcatcaaaa cgagtttttg gtaacgggct
     2701 ttcgaaacat caaattctgc gccaaatcct gttcccatgg ctgtgaaaag actacgaatt
     2761 tcttcgttag ctagaatctt atccatactt gctttttcaa cgttcaaaat cttaccgcga
     2821 attggaagga tagcctgaaa ctcacggtta cgaccagatt tggctgatcc accagctgag
     2881 tctccttcga cgatgaagag ttctgtttca gcagggttat tagaagaaca gtctgctagt
     2941 ttccctggaa ggttggaaat ttccaaacca gattttttac gtgtgacttc acgcgcacgc
     3001 ttggcagcca cacgagcctt ggcagctaaa atcccttttt ccacgatacg tttggcaatc
     3061 tgtggatttt ccatgaggaa atcggagaag gcttcactga agaggcgatt ggtaatcttg
     3121 accacttcgc tatttcccaa tttggtcttg gtttgtcctt caaactgtgg atttgggtgt
     3181 ttaactgaga taactgcagt taatccttcg cgaacatctt cccctgttaa attatcttca
     3241 ttgtctttca gtaacttatt cttacgagca taatcattga taacacgagt cagtgccgta
     3301 cggaaacctt gttcatgcgt tccaccttca tgggtatgaa tattattggc gaaactcatg
     3361 acattttcat ggtaacctgt tgtgtactgc atggctactt caactgtaat atcatccatc
     3421 tcaccgtctg tatagattgg tgtatcaaag attacatcct tgttctcgtt gatatattca
     3481 acgtaactag caatcccacc ttcataatga taatgcttgg tttgttccaa accttggcgc
     3541 ttatcagtga tggaaatttg aagaccgcga tttagaaagg ccaactcttg aatccgttta
     3601 tttaatttat caaaatcaaa gattgttgtt tcagtgaaaa tttctgggtc cggtgtgaag
     3661 tgaaccgttg ttccagttct atctgtatcc ccaaccacct caaggtctgc aacaacatga
     3721 ccacgacggt attcttggta atgaatctta ccgtttttat ggacataaac gtctaattga
     3781 gtggaaaggg cattaactac tgacgacccc accccgtgaa gaccacctga aaccttgtat
     3841 ccaccaccgc cgaactttcc tccagcatga aggactgtaa agacggtctc aacagcagga
     3901 cggcctgttt tttcctgaat atcgactggg ataccacgcc catcatccac aacagtaatc
     3961 gaatcatctg gctcaataaa aacttgaata tggctggcaa atcctgccaa ggcctcgtca
     4021 attgagttat caacaatttc ccagactaga tggtgaagac cttcttttga ggttgatcca
     4081 atgtacatcc ctggacgcat acgaacagcc tctaagccct ctaaaacttg aatttgactg
     4141 gcatcataat cctgtgcctg cagatttttg atttcttctg tcatcttatt cctttttctt
     4201 atatgtctaa tacttgtctt aaattcacga tactggtaaa caagtgggta tcaagtcctg
     4261 cagcttgacc tgcttcgata tcaatcggcc gatcaccaat gacaagacca gagctaatct
     4321 gatacttttc tcttaaataa agcatggatt cgggatttgg ctttctctta aagcctgagc
     4381 tagaagtcac cacttctgta aaataagctg ctatagaggt tttttctaaa atttccaaaa
     4441 cctgatcatt tcgatgagag accaaaaaat gacggccacc ttgatttgaa atgacttcca
     4501 ataggtcaga aactccttca aataaaatcg ggtgttcaag ctctctggct tcattttcct
     4561 tgtacttttc taaaaaattc tctaaattgg gagcgaatgt ctcaatcgca aaaggagtag
     4621 aaacctttaa agcttgatag acactgtcat ggtcttgtgt gataccatac agtgccaatg
     4681 tttcaacaaa tgcagctgtt gaagtttcat aattatccag taaagttcca cctaaatccc
     4741 agatgtaatc gtgatatttc atgcccttta ttatagcatt tttttatgaa aaaagcgatg
     4801 atttccctga gttttccaca taaaaaacga gagaataact cccgttttac tgatttttac
     4861 caaagacatc ttgatagagc attcctgttc gtaaactctc tgcgtcccct cctagttgct
     4921 ccaccaactc gtaggcaaag gcaagggctg ttgaaggacc ccgactggtt gtcaactgac
     4981 catctaccac tactgtttcc ttgacgtagt gaccatcaag gatttgctct tgaacgccgt
     5041 cataacaagt gtatcgctta tttttcaata tctctgcttg attgagggca attggtgccg
     5101 cacaaatggc tgctagtttc ttcccttctt gctcgaagct ttgcaattct tgaatcaagg
     5161 tctgattatc acgtaaatgt gcagaaccag gcatacctcc aggaagaaca atcatatcat
     5221 agtctgataa atctccatca aagacatgat ctgctcttac ttggattgca tgcgaacccg
     5281 ttacttgctc ttcaaaacca accatatcac atgtgatatt ggctcgacgc aagacatcta
     5341 caactgtcaa ggcttcaatt tcttcaaagc cctgagctaa cataactgct acttttacca
     5401 tgattttctc cttatttaat ttgttttaat acaacctttt tccgtttgaa tgggactttt
     5461 ccgctctttt cttcagctaa attagtctgg taactcatcg ataaaagcaa accaacacca
     5521 atcaaattac tgataatagc tgatccccct tgcgaaatga aaggcaaggg aatccccgtc
     5581 aaaggaagta gtccagtcac agcaccgata ttctcaaaga tgtggaagag caacatcata
     5641 atcaaacctg tggaaatata agtgtagaac tggttatttg atttaagagt aatcttcaac
     5701 atacggtaaa tcaacatgag atagagggca ataaccagga cagagccaat aaagccaaaa
     5761 tcttctgcaa taaccgtaaa aatcatatct gactctcgaa ctgggataag cagattcgaa
     5821 gcattaaatc cctgaccaaa taagccacca ctcccaatgg caatctgccc ttgagcctgc
     5881 tggtaagtcg ttgtttgggc aaactcaaag ggattgagcc aagccaaaat ccgattaatt
     5941 tggtaggtcg gcattccaat ctggtgaaga aaagctcgtc cgtccttgct aataaagata
     6001 gctaagaaac cagcaactcc tgttacagca gtcacaaata ctgggataat aattttccaa
     6061 gaaacccctg ataataaaac gattcctgag aaaatggcta caaaaaccaa agccgtcccc
     6121 aagtcacttt gaagtgctaa aagaactagg actggaatgg taaagagaat catccagaaa
     6181 attaacaaaa agtccagcgg aaccgtgcgt ctccattcct tatgtttctt tgtaaattgg
     6241 acaatgacac gagccaacat gaggatatag gatatcttca taaattctga cggttggaat
     6301 agggtaattc catttattga tacccagttt ttggcacccg ttgatgcaac taagcttgga
     6361 ttataaaata caatcggcaa gatcataagt cccaagccta aaatatatag aaagggggtc
     6421 accttccaaa gaaattctgt attaaagagc atgaccacaa aaccaatcac aagccccaag
     6481 gcaatccagg cgacctgctg ccctaaaatg ggcagaatat tattgggata atcatgacta
     6541 acggctatat agatagccac cacaccgatg accagtagaa aaaatactgg caagagcaaa
     6601 ctgtaatcga ctcttgagtc gagagaacgt ttcatatata ctaaccttat actttcatac
     6661 aatactattt atcaaagttc attaaaaaat ctatcaatag cctcgtcaac ttcggatcga
     6721 gagatggttt taacagtcgc ttcttctgct agagatgcta ctatttgttt gccgtatcgt
     6781 tttccgacga ttctcctatc caaaataaga gttaaggaac gttggtattc acgtctcata
     6841 cttcttccca aagcctgttt taaacgaata atggccattg gcaattgata atcataaaag
     6901 gcatttttcc cttcttgatt cagttcttga ttaatctttt tcgtcaaggg ttcttgagga
     6961 ttttggaaag gaagcctcgg tacaacttga atcacaaaag gatggcttga aaaatcaact
     7021 ccctcccaga aacttgctgc accaagcaag atttgttgtt cacctttttc aaagcgtttc
     7081 tttagctgat gaacatcccc atttttatac tgggccaagt ggctaactgt aagtaaatcc
     7141 gatactgcta gaagcatgtc tttagcggta aagagaacca aaatcggttg ctggaaagct
     7201 tgaatttcca ctagtaaagc agctacctct ctggcataga cttctaagga ggtttctgtt
     7261 accagaggga aatctttgac cataaccact tcttgttcct gttttccccg agattcaatc
     7321 ttgacaaatt tggcttcagg atagcctaaa aggtctgcca aagaaaccct ctgactaatc
     7381 tcaagagtag ccgatactcc caagacttgg caactctcag gaagtaaaga ggacagaaga
     7441 gtacggcctg attttgtaga agaaatctga attttctttt gactcgtttc agttacttca
     7501 agccagtaat caccttcagc tgtaaaatag cgaaccagct catcaaagcc ttctacttct
     7561 aattctgaaa aatactgatg gagattgtcc agagaatcta agatattttt cctagattta
     7621 ccagactgaa attgttctat caagtagaga cactcaaagc gaatactttc tagtatccgt
     7681 tgttgaaccc tgttttcttc tcctactaaa gccttatcaa ttaaatcgat aatagattgt
     7741 atatcgtagg tctcttgaag cagattttct agagctaaca aaatcttttg gacttcatca
     7801 ataatcagta aacggtcact gacaaattca ggattatctt caagtctggt cacgagatag
     7861 gcatgattag tcactaaaag cttgcaagtc tctgcccttt cttgactacg tttccaaaaa
     7921 tcttccgtca caaataagct ctgggatgat aaattcccat catgacgaag gtctgctaga
     7981 aaatgttggt aacggtagag ttgcccgatt tcatccaaat ctcctgtctc tgtctcagta
     8041 agccagacca agacttgcat tttaaagcgt ctaaataagc gattttcatc attttcctgc
     8101 aaggaatgat aaaaggcatc caacttcaga taattttgtg gtccctttaa gctatgaata
     8161 tctgtatgga acacttcctt gagacgttta ccttcttctt ccatgatttg attttgaaga
     8221 atctttgtcg gaacactaag aacaatttgt cgctctttgg attgagataa agcgggtaag
     8281 agatagccat aggttttccc aatccctgtc ggcgcttgaa tcagagagac aggttcatct
     8341 ttcaatagca agacaacctc tttagcaaaa ctttcttgtt cctccctcac ttcaaggttc
     8401 aacagagaaa tatttttaga aaagtcttga gatagttttc gtagctccag agaagctgcc
     8461 gttttcttaa aatacagacc ttgaacttgg accaagtctg gagaactcag gatagattgg
     8521 ttgcgataag tttcctcaat aaccaggtag gactcatata ggagagcgtc agccatttcc
     8581 agcaagcgtt ccaagagacc tttaggaagc tgggtcatct tttcccgtaa aaaaagaagt
     8641 aattctgctg tagcttgggc atctgaaagg gctgtgtgtg cgtgtttaag aggaattcct
     8701 aattctcgac acaaaatcgg caagctatat ttttccagtt cagggaaaaa gacctgggcc
     8761 aattcgaccg tatcaacacg agggtttctt agctcatagc cttcaaaaaa taaattttcc
     8821 gccaagagat tagcatcaaa ctgaacatta tgggctacaa aaatcccatc ctccaccaag
     8881 tcaaatattt ttctggcaac ttgcgaaaaa tcaggtgctt gcgccagacg ttggtctgtc
     8941 aatcctgtca gttctttgat atgagcatcc aagggttcat gtggattgac atccgtcgta
     9001 tagtgatcga cgatttctcc gtcctcaatc acgacaattc ccacttggat aattttagcc
     9061 ttactacctg tgctagttgc ctctaaatcc accacaacat agcgattacc aatcgttttc
     9121 attataaaaa attataccaa aaaaagggct atttggcacc tgcaaacata ggataatttt
     9181 caaactcaag aacactactt ttcttaaaaa tcccatcgaa tagagcattc tagcctgctg
     9241 atttttgtaa aatagtgaag aaatacgaaa aattgagaga agaaatgttt tcatcttcct
     9301 tctctcaacg aatcatgtat tttatttaac catgtcagga tcgtagtcat aaaatcctgt
     9361 atcaaggaaa cggtttttag ggtgaagttt acgaacttct tcatccagca agaaggcttg
     9421 atcatggcta aagttgccct cttgaatcaa gttacgcgct tggataaaga gttttgcaat
     9481 ctcaacaaag ttctgaccag gagtgtagag cccttctagt ttccagcgag taaagccatg
     9541 ctccaccaat tctgttaatt tgatcatcaa atcaaggtca ttgttggcaa agatatgggt
     9601 cccatgatta tcttcaaaaa tggaatagtg gctctctgga tcacttggct cagccaagaa
     9661 gaggtcacgt ttatgcgtct tttcatcatc gatatgtgta aagttatagt agttttgcaa
     9721 gagtggacgt ttagaatgat ggatgacgct agcaccgtaa accaaaactt cagcaggaat
     9781 ttccaaaatc tctggcattt tgaaaagttc agctgatgga atttcacgcg ccaaaacagc
     9841 ctcagatgca ccagcctttt gtccccagaa gttaatctga cgactgctag ttaccatggt
     9901 tgaagcatcg tagatggtct taaatgaata accatcgcgg ttaactacgt aaaagacgcc
     9961 tgcatcccca atcgtaatat agtctgtctt gatttcttcc aagaagtcta agaaaggctt
    10021 gatacggtcc atcatatctt ggtgcatgag agcattgacc gcaacgagca attccttacc
    10081 agcatcatga accaacttag cgatttcacg taattggtca taactaaagg tcgttggcag
    10141 acgaaggcca aaatctttct caccgacata gatacggtct acgccagctt cgagtagttg
    10201 ttcaacttgt tcaatacttt cagcagttgc tgtaatgaca atcttttcca taagaaaaat
    10261 tataccacat ttctccaaaa tcagccatgc tttgaaaatg aaaagggact ttattctttt
    10321 tgtaaccttt ctgtaataat tctctgccga aaaaatgata aaataggtat gtactgttaa
    10381 ggagagaatc atgcccgtaa gaaaattaca atcctatgag gtagactatc aagaagaatt
    10441 aaaccagcag cttcctcatt accaagctta tacacctgaa gcgcaatctg atgccaatct
    10501 caaggaaatc ctatttttta ttaatatcgc tgttttttgt atctgtattg ctatctttag
    10561 ttttatcttt ttagcattaa aattatcaac tgctcttgcc tttgccgcag caatcggatt
    10621 cagcttactt gttttaaaag ttcaacggtc tattatcaaa cgaaaacgta gaagataaat
    10681 ccaaaatatc gccccaattg gagcgatatt tttatttttt ctttttagat ggtgtctgaa
    10741 tggcaatctt cacttcaaag attgttccct tgggtttatt atctttgaca gtaacagttc
    10801 cttttagagc atctacaatt tgcttggcta gggataatcc taaaccaaaa ccaccttttt
    10861 gccgggttct agccttgtct actcgataaa aacggtcaaa aattttcttt ttatcttctg
    10921 tcgaaatacc gattccatta tcagaaacaa gtaaataaag attgcgatcg gtcgccgaga
    10981 taagaaaatc aatttcacca tcctcctcag tatacttgac ggcattatcg aaaagaatgg
    11041 tcatcagttg tttcagaaga agctgatctg tgacaattgt tcgatggata cgattttcaa
    11101 aacggaagac acgattattt tccgaagcaa tcatctcata gtttgtgaaa gttgtattaa
    11161 aaaagctagt tggaacttct gcaagctccg gcttaatccc atcatctctc cgagctaagt
    11221 tcagcaagct tgtcgttaaa aaacgcatat ttcggacttc ttccaaactc gatgcaatgc
    11281 tttcgctcac atccataatg gtagcttctg gcttacgaaa aagggtctct aagcgatttt
    11341 gcaaaactgc gagtggagtt cgtaactcat gactggcatt ttccacaaaa gactgttgct
    11401 tctgcatact ctcaagcaag ggcctaacac tgaccctagc tagatagaga ctggcaagta
    11461 aagacaaaat ccagaaacta gccatcacga ccacaatcaa ttgctcatgc ttttgactag
    11521 cctgctccaa ctgactggta ttaatcaaga cagcagcata cttgatattg gttgaaaccg
    11581 aactaatatt ggtctccatc aaaatcacac gatagatttc ttcctgccca tagctattaa
    11641 aaacctgaat ctggtagata tgtcctagtt ctttcttttc taacttaatc ttatccaagc
    11701 ccaaaaatcg atttccagaa agaagttgag taaagtcttt atcaaagaga atgacttccg
    11761 tattggaact gacattaggt tttatttcta ctttactagc gtccgcccta gcattttcta
    11821 aatctttaat ctcttctgtt gccctattta tagccagctg aataactgct tgaggatttt
    11881 cactcagtcc atgaagctta tcgtccaccg aagtataaag actcgaatgc atgacttgta
    11941 aaataatcag agtcattgta gaaaaaatca gggtgaagac accgaagttg cggataaaat
    12001 aactaaagtc atccgcatac catgtttttt taagtttact gaacatcttt taaaagatac
    12061 ccaacactac gcaaggtttg caaattctct gcaaaagtgg ttccctttaa tttcttacgg
    12121 acttttgaaa catagacttc gacaaccgaa atcgttgtat cactatcaaa tccccataga
    12181 cggtcaaaaa tctgcgtctt aggcaaaatc acattttgat tttgaaggaa ataaactagt
    12241 aaatcgaact ctttccccag caattcgaca ggagtatctt caactttaac ggtattggtt
    12301 gataaattaa ccacgatatt cccataagtc aaggtgtttt cattaaactt ccctgaacgt
    12361 ttgagaaggg cctgaatccg cattttaagt tcttctaggt agaaaggttt ggtcagataa
    12421 tcatccgctc ccagttcaaa tccatgtccc ttgtcatcca aactttcctt ggcagtcata
    12481 atcagaactg gtgtcgtaat tcccttttca cgcaattctt ttaagacttg gaaaccattt
    12541 ttttctggca acatcaaatc cagcaaaatc aagtcataga caccactctc agcttcgtag
    12601 agaccttctt ctccatcaaa tacctgcata acatccgcaa aatcgtctaa aaagtcaaat
    12661 actgaatttg acagacctag gtcatcctca accaataaga tttttatcat gagaaactcc
    12721 tccttattaa aactattata ccaaatttgc cttaaaaaaa actcaactct ctgcatttta
    12781 catgagatag ctgagttttc tttttatttt aggcttattt atgcatttcc gtattgaaga
    12841 acaactgctt cgactgcagc tttttcacgg ctaatcaagt caacacgtgc tgcaatttcc
    12901 ttgattccca taccgatgtt acggctaaga gcaaggtcag aaagttgcgg ctcaaagaac
    12961 tccttgtatt ccgccaagcg ttgctgagtc ttaaatacat gagcaggaag gataacaaag
    13021 ctatcaaagc tcatatctcc tccaagggct gccttaatcc aagcccagtt ttcacgcgcc
    13081 caagaccaag ctgttttctg agttgcttga tgagctagga attggtaata ccaagcagac
    13141 aagtcctgtg gtttgaccac aaatttgtcc ttccaagaag taatcaagtt ttggatatta
    13201 tccgcatctg tactgtatgc aagagctgct gccaactggc gtttaaagac agcatctgtt
    13261 gcgtgagtat aagtatcaag ataaagtgct aacaagtctt tagtctcatg atgtttcatc
    13321 tcattaatca gaacttgtga acgaatagct gctgggagtc ctgcaagatt ctccttgtgt
    13381 gttgcgaaga tttggctagc gacttgacta gcttctgcat catttgagcg aatcatcatc
    13441 gaaacagcca gctgacgaac caattcatcc tcatctgatt ctccgtcttt agcttcaaaa
    13501 ccaagacggt catagttatg acgagccaat ttagcaacca gtcctttgaa ggctgtttca
    13561 gcatccgttc cttcatcaat aaagcgctca agggctgaaa tcacttgaga aacagctgaa
    13621 accaccagat aagactcttc cttagcaagt ttatcaagaa ctggaagcaa gtctgcataa
    13681 gaaatgtgcc ctgcctcagc caacaaacga cgttcttgaa caatttgcag tttgcttgtg
    13741 ttatcaagtg tctctagctc agcaagaaca gcttctaaca agtctccttg atagtcggta
    13801 atatagtggg cagtattttc agtgttgaga cgaagagctc cttcattttc agcaagaaga
    13861 gctgcgtagc cagggatttc gatactttca gtttcgagtg tatcaggcaa gcctttccag
    13921 ttgctattga ggggcaccac ccagagacgg ttcttgtctt cgttctcacc gatgaagaat
    13981 tgtttttgtg aaatcttcaa gacatcattt tcaactttaa cagtaagaac tgggtaacca
    14041 ggctgttcca accaagaatc catgaaggct gcgacatcac gtcctgacgc ttgaccaagg
    14101 gcatcccaaa ggtcactacc aatggtgttg ctgtattggt gtttttcaaa gtaggcgtgc
    14161 aaacctttag caaaatcagc atctcctagc caacggcgaa gcatgtgcat gagacggctt
    14221 cctttggcat agacgatagc gccgtcaaag agtgtattga tttcatctgg atgtttaact
    14281 tcgacgtgga cagactgaac gccatcagta gcgtcacgtt caagagcaag aggtactcca
    14341 cctgtttgga aatcttcaaa gatattccag cttggttcga tggtatccac acagacgtat
    14401 tccatcatat tagcaaaact ttcattgagc caaaggtcat cccaccattt catagtcacg
    14461 aggttcccaa accattggtg agccaattca tgggccacaa caagggcaac ttgttgacgg
    14521 ctagcaaatg tagagttctc atcgacaacc aagtaaactt cacggtaggt cacaagaccc
    14581 cagttttcca tagcaccagc tgagaagtca ggaagggcga tgtggagaga ttgaggaatt
    14641 gggtacttaa ctccatagta atcttcgtaa aactcgatag agcgaacagc gatatccagt
    14701 gagaaatcaa gatttgaaag tggatgtgct ttggttgagt agacacctac cagggtacca
    14761 tttttagttt tagcggtcac cccttgcaaa tcaccagcaa caaaggccaa caagtaagaa
    14821 gacatgcgag gtgttgtctc aaacttccag atacctgttt ccttacggtt ttcaacatcg
    14881 atttctggca tgtttgacaa ggccaattca ccttctgctt ggtcaaagcg aagagagaga
    14941 tcaaaagttg ctttggcttc aggctcatcc acacatggga aagcttcgcg cgcaaaatgg
    15001 ctctcgaact gagtagacaa gacctccttc ttgactccat caactgtata ataagaaggg
    15061 taaatccctg tcatgttgtc tgtaatttta ccagaaaagg caagaaccaa ttcaacttga
    15121 ccagcctcag ccaattcgat atgaagggct tcattgtcat ggtcaactgt aaatggacga
    15181 gcttgacctg caacttctac agaggtgatt tccaagtctt tttggtggag ggagatgcgg
    15241 tcactctgtg cttgaccagt gatggtcact ttcccagaaa aagtcttggt ctcacgactc
    15301 aaatctaaaa ataaatcata atgttcagga acaaattgct taataaaatg ttcaactgct
    15361 tgcatagttt tctcctattc taagtttaag agctgctgct cttcttcaaa caaacttatt
    15421 atatcatatt ttgcttgaga aaaaaggatt ggacagcgat ttccaaaact ttcttccttc
    15481 taatagtcta cagtgggtag accttgcgaa attcttctaa aacaaccttg ctttcaggtg
    15541 taaaagtcag ccctacttca cccaaacagt ctgtgaaaaa gtcctcatga gcctggcgcc
    15601 aataggcaag tgatttgtct ccctcacctt ccttaaaggc atgttgcgca gagacttgat
    15661 tgaagagttc aacagaaacc tttgtaattt cgacaatgca gacagactga ttttgactat
    15721 ctaaaatgac atcgaaggtc cctacttggg gaagtggttc gtcttctagt acatagaggt
    15781 cataggctga tgctgttgct gtcttttctc ctttaaacac caaatccgct aaaaggtctg
    15841 gttcaactcc aaaagcccaa gcatcgattt catctccgat caaaggattg atttgcttgt
    15901 atttattcca catttcttgc ggtatcatgg gtactccttt gtaatttttt actttcttct
    15961 tttatgtgtt taagatgatc tggatggtca atctctaaat caaaaatctc tggaatagaa
    16021 ctgtagtgga taatgcactt gatacccaac tgattcattt tttgtatgaa agaagtattc
    16081 agatagcctg ctacagcaaa attaatcttg ttctttcttg ctttatcctg catatctctt
    16141 agcatatcta acattattgg actttccata tcatgccatt gactgtttct catagtcgca
    16201 aaaacaaagg aagtcaaatc attcattcca actacaatct ttgaaatgcc cgtttccagt
    16261 atactagata agtcaaaata cgctgacggt aattcaatca tcgttccgac tttcccagta
    16321 aagccatact gacgcaatac tgtaatagct tgttttaatt ggtcggcatc attgacagaa
    16381 ggaaagataa gagatagatt ggggttggtt tgataaactt ctgtaacgac atgtgcttca
    16441 gcctgaaatt catccaaaca cgccagtaaa cgtctggttc ctctatagcc aaacaaggga
    16501 tgcccttcgt caaaaaactc tctagtcccc actaaacaat tggcttctgt attcgttaat
    16561 tcagaaaaac gataccaaac ttcttcatct gagtacaggg agcagatagt ctctagataa
    16621 tcttttacaa attgctgaca acttgctaat atgatgtttt gattaagctc tctcaacaaa
    16681 tattccccac gaatcatgcc gacgtggtga aatagttgag gataaatttt ttcaagaatt
    16741 ttttcgccac taagggcaag ttgatttctc atagccattc acctcgtctt aaaagataca
    16801 atatcatata taattatatc aaaatttcct ctagttcaaa agcttcataa ggttcagata
    16861 actcatatcc taaaaattct gctacttttt tggaagcctc attatgagca tcccaaagtg
    16921 gaaacatatc tctatttaaa ctctctagaa tcattgcagc accaagcttt ttagcaaatc
    16981 catttccttg ttcgtttggt ctagttgcaa cttccacttc aactgcttta cggtaaacta
    17041 accctgagga aatcccagca atcagttcat tatttttaag aatcacaaag ccaaatccac
    17101 cttttaaaac aaaatcctga taggactcaa aatccccctg taaatcctgt gaccattctt
    17161 ccgtagaaaa gcagttataa atatgattat caataggcac aatattgtaa ccttcctcta
    17221 aatgagtaac tagattattt aaaaattcaa cttgaaaatt tgccttatct ttaaaagaat
    17281 agcgagtaaa agaatttagc cccacttttc gatgcagaaa atcttgccaa ttagtatttt
    17341 ctgaaataat aatcttataa tctaaaccat attttctaac aaaatcttcc caaaatctgg
    17401 aatccaactc ccctgctagg tatagaaaat tcccaacatc ataaaagctt gttgtcctat
    17461 cattgtttcg gtagacagtt ccaatttgag atttaagacc atagagaacc atatttttct
    17521 tccatgtttt aaatagttcc attatccctc tacttcacct tccaattcat gtaagaagtc
    17581 ttgtccagtt ctggcaatcc taataattca gacttaacct tcaagactaa tggcgatgca
    17641 ttttcttctg taatctcttg aatatccatc caaatatatc caagtgaatc attcgcacca
    17701 tcagacacag cttccgaaat cgtaacttga ggtgcactct cattcatttc aacatcatac
    17761 aaggctatga catggtgaac cataaaattt tttaactctt ccctgacgaa aacatcgtag
    17821 attcgaggat tagagtagct tctaacagta aatcccgtct cttccataac ttctctagtc
    17881 agcgtttccg tcagtccttc accaagttgc tgactgcctc caggtagatc ataccgatgt
    17941 tgataagggc ctctcgtttt ttcaatgcaa agtaactttc cattttcaaa gcaaacacag
    18001 tagaccccaa agtgattttt gatttccatc caactcctcc tacttcaaag accagccacc
    18061 atctattgtc agaatttgtc cctgcatggc agatgccttt ccactggcca aaaagagact
    18121 gacttctgcc acttcctctg gttcaatcca gcgcttgatt ggtgtttcac tagccaccca
    18181 gtcagctaag ccacctgtct caaaatccgc agcggtcata gctgtcttga ctgctcctgg
    18241 agcgatacca aagacctgaa tcccagcttc agcatagtct agagccaact gcttggtgaa
    18301 gccagccaag gcatgcttgg atgaagtata ggcgtgacca cctccacctg ctaggctaga
    18361 agcaatggaa cacatattga tgatgattcc ctttttattt tccagcattt gtgtcaaata
    18421 ataccgagtc aactctactg gaataatgta gttgatttca aaaatctctt gaatgtcctg
    18481 cgccgtttgt tccaacagtg gtttgtaatc atccaaaact ccggcagtat tacacaaaac
    18541 atccacctga gggcaccagt caaaaatagg ttccaagtcc aaggtcaaat ctctctgtaa
    18601 aaagtgaaaa tcaccctcta agagtggctt ttcaccttgg tcaactccat aaacttgata
    18661 gcccttctct aaaaagaggc gagcttgagc caatccgatc cctgaactca ctcctgtaat
    18721 gagtacacgt ttagtcatgc acttctaccc aatccgttgc caaaacatca caaactgtcg
    18781 ggctccacat ggaaaaacct tctccttctc cagaaacgtt gattaggaaa taaggtgtca
    18841 tttcaagtgc aagcccattt tgctcgatgg tatcaaagag ttggacatag ttttccgcac
    18901 ctccccaacc agttcgtaca tattttctct tagcctttaa cccaggcagg atctcttcaa
    18961 atgtcatgtt tttctccttt aattctacat tcttcattta attatagcaa aaaaccactt
    19021 tatacggctt tttgactgtg agttattcaa acctgctact acttacggca aattattccc
    19081 tgcagcaaga taaatttcat accattcttt tcttgttaag ctaaagtttg ccgctcggct
    19141 aacttctctc aagtgcttag gatttgttgt acctacgact gcctgcattt ttgctggata
    19201 acgcaatatc caagaaatgg caatagttga agaggttact ccatatttaa tagctaaacg
    19261 atcaagtact tgatttaaag cttgaaattt ctcatttcca acaaagttcc ctttaaaata
    19321 cccgaattgc aagacagacc atgcttgaat gaccacatcg tgtaatttgc aatattcaaa
    19381 aatgctgcca tctcgcatag ctgcttgact atcttccata ttaacatgaa aagctgattc
    19441 aaatcctgga gtaaaagccg cactcaattg tagctgatta acagctaacg gctgcttgac
    19501 atctttttta agcaactcca tcatcatagg attttgatta gaaactccaa aatctcgaac
    19561 tttaccttgt ttataaagga gatcaaaggc ttctgctact tggtcagatt ccatcaaagc
    19621 atctggtcga tgaaggagca agctatctag atgatcaatc ttcaatcttt gcaaaatacc
    19681 gtctactgat tttataatat agtccttaga aaaatcaaaa taggtaaatt cttcaatgcg
    19741 aatgccacat ttggactgaa tccacatctt ttctcttaaa tctggacgat tttttaggac
    19801 aagacctaac agttcttcac aacgaccacg accataaata tcagccaagt cgaaggcatt
    19861 gattccaaca gaaagtgctg tttctacaag ctcttcaact tcttttacag acttatcttt
    19921 tattctcatc attccgagaa caatttctga taattctttg tcatcttgac caagagttat
    19981 gtatctcatc aaatttttct cctttaattt ctaacattct tcccttcatt ataacaaaaa
    20041 accgctttgc aacggctttt tgactatact tcactccatt ttatcttctt aaacccacgg
    20101 aacaagacaa agattccaat aaagaggaca gctaaaggaa taacttttgt aaggaaaaca
    20161 tttgaaattc ccatctactc ataataacgg agcagagaac ccaccacaag atgggcaata
    20221 atcatactga caaatggacg aaagaccgct tctttccaat tccaaatacc gataactagc
    20281 gaaatcgtaa agacagacaa actatcccag ggagccggaa tataaaaggc tccttcttgt
    20341 atgaagcttg ccattcctac atatcctaaa acaactagaa gaactatagt cccaacaaca
    20401 atgtaagtgc caattttcat tttaggagaa tcttggacta aacttcttcg taaaattgtg
    20461 gccacaagtc caaatccaat cagaaaaata agaagttgcc ctaaaaatgt gagcaaattg
    20521 actgttaaga gaggaccttt agaaaaatca cttagtagtt gataataacg taataccgcc
    20581 aggacaagaa ttggcgtcaa aagggactct ttgatagaac tgcgaggtgc tcccttgaga
    20641 atctctttca ttattttttt aggattctta cctagataat cctctgcact catgccatct
    20701 cgttctgctt ctgagaaatc tagcatcatc aaatagatct gctctctgag atagtcttca
    20761 tcatagagaa atccagcaag attaaaactt tcccacaact cctcaaaata cttttgattc
    20821 tcctcagaaa actcatgtag caaagcgctt gtttcttcgt aatacttcat tttcttcatg
    20881 gtttaacccc cattcttaat cccttctact ttttgactca aatcgtccca ttgttgccaa
    20941 aagactgaga cacgctcttc tccttctttc attaatgaaa aatacttccg atctggacca
    21001 tctggcgacg ggcgcatgtc gcctcttatc cattgatttt tttctaactt ttgcaacaaa
    21061 ggataaatag ttcctggaac gatagtatca aatccagcct ctcgcaaagt ctgaaccaac
    21121 tcataaccat accgctcttt ttgaccaatc atatccaaga cacaaccttc aagaacacct
    21181 tttaatagct gagtttcttt catcacttct cccttctaat ctattttgta atacctacta
    21241 gtaacttcac ctatagtata tcacttctac actagtttgt aaagcataat agttaatact
    21301 cttcgaaaat ctcttcaaac cacgtcagcg tcgccctacc gtatgtatgg tt
//
LOCUS       DAVKUR010000035        21203 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKUR010000035 DAVKUR010000000
VERSION     DAVKUR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.035"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..928
                     /locus_tag="VW749_001436"
     CDS             <1..928
                     /locus_tag="VW749_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0175460.1"
                     /translation="TDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNK
                     LKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTAN
                     IKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDFFAERRSLNAEVVIKGVCLDPRIG
                     NFYNNPSFEFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPK
                     IVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELF
                     TKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            1323..2186
                     /locus_tag="VW749_001437"
     CDS             1323..2186
                     /locus_tag="VW749_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0175461.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRLQQYKKLID"
     gene            2472..2669
                     /locus_tag="VW749_001438"
     CDS             2472..2669
                     /locus_tag="VW749_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0175462.1"
                     /translation="MLNLQFAETMELTEAELETGYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            2737..3402
                     /locus_tag="VW749_001439"
     CDS             2737..3402
                     /locus_tag="VW749_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175463.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3474..4700
                     /locus_tag="VW749_001440"
     CDS             3474..4700
                     /locus_tag="VW749_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0175464.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLT
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(5050..5127)
                     /locus_tag="VW749_001441"
                     /pseudo
     CDS             complement(5050..5127)
                     /locus_tag="VW749_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5198..5854
                     /locus_tag="VW749_001442"
     CDS             5198..5854
                     /locus_tag="VW749_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0175465.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            5844..6167
                     /locus_tag="VW749_001443"
     CDS             5844..6167
                     /locus_tag="VW749_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0175466.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            6270..7100
                     /locus_tag="VW749_001444"
     CDS             6270..7100
                     /locus_tag="VW749_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0175467.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7254..8108
                     /locus_tag="VW749_001445"
     CDS             7254..8108
                     /locus_tag="VW749_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0175468.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            8208..9581
                     /locus_tag="VW749_001446"
     CDS             8208..9581
                     /locus_tag="VW749_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0175469.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9574..10635
                     /locus_tag="VW749_001447"
     CDS             9574..10635
                     /locus_tag="VW749_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0175470.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            10637..11329
                     /locus_tag="VW749_001448"
     CDS             10637..11329
                     /locus_tag="VW749_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175471.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11358..11927)
                     /locus_tag="VW749_001449"
     CDS             complement(11358..11927)
                     /locus_tag="VW749_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0175472.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            12062..12676
                     /locus_tag="VW749_001450"
     CDS             12062..12676
                     /locus_tag="VW749_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0175473.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12678..14324
                     /locus_tag="VW749_001451"
     CDS             12678..14324
                     /locus_tag="VW749_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0175474.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14336..15622
                     /locus_tag="VW749_001452"
     CDS             14336..15622
                     /locus_tag="VW749_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175475.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15674..16207
                     /locus_tag="VW749_001453"
     CDS             15674..16207
                     /locus_tag="VW749_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175476.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            16285..16755
                     /gene="nrdI"
                     /locus_tag="VW749_001454"
     CDS             16285..16755
                     /gene="nrdI"
                     /locus_tag="VW749_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0175477.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(17048..18310)
                     /locus_tag="VW749_001455"
     CDS             complement(17048..18310)
                     /locus_tag="VW749_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0175478.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18620..19078)
                     /locus_tag="VW749_001456"
     CDS             complement(18620..19078)
                     /locus_tag="VW749_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0175479.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(19075..19515)
                     /locus_tag="VW749_001457"
     CDS             complement(19075..19515)
                     /locus_tag="VW749_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175480.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19948..20814
                     /locus_tag="VW749_001458"
     CDS             19948..20814
                     /locus_tag="VW749_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175481.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
BASE COUNT         6343 a         3758 c         4623 g         6479 t
ORIGIN      
        1 gacagattat gatgagaaaa ttggtagttt taatacatat gaaatcgaac aaacggtatc
       61 gaagattctg agggtaaaac ctaatggaaa gattatttta aagtcaacag ttccgatcgg
      121 cttttcaaac aaattaaaaa ggctgtttga tacaaaaaat atcatttttg tccctgaatt
      181 tttgagagaa ggttgttcta tatatgataa tttatatcca agtcgcatag ttgttggaga
      241 tgagacagtt gaaggaagaa aaattgcaga gttgttcctt tcgattagta ctcatagtac
      301 tgccaatatt aaaaatgtta tgttagtttc tcctactgaa gcagaagcaa ttaagctttt
      361 ttctaacaca ttcttagctc tccgtgttgc tttttttaat gaactagatt tttttgctga
      421 gaggagaagt ttaaatgctg aagttgtaat aaaaggtgtt tgtttagatc caagaattgg
      481 aaatttttat aataatcctt cttttgaatt tggaggatat tgtcttccca aagatactaa
      541 acaattaaaa aaagaattta tagaaataaa tgccccagtg atagaagcga ttgatatttc
      601 aaacacaaat agaaaacagt tcatagttaa acaaatattg gaacgaaagc caaagatagt
      661 aggaatatat aaattgggga tgaaatataa ttcagataat tacaaagagt cagctatttt
      721 aagtataatt aatgaactat tgattgtcgg tataaaaatt ttagtatatg aaccaaattt
      781 aaacgttagt atagataacg taatttttga aaagaatttt gaactattta caaaacaaag
      841 tgatctaatt gttgcaaata gatgggatag gggccttgaa gcttataaag ataaagttta
      901 cacaaggggg atctggataa gagattaact attgatatta aaaaggcaat aatttataaa
      961 atttgtacaa aaaaatgtta aattttcaca ttttcatagt atactgttta atagaaagta
     1021 ggttctttgt aaccgctcca ttataaaatc ctttcactct tccggtatgc tattaggaaa
     1081 aacataattg gaggatattt tgagctcaca cctcatcgtt ccagtggctg ttccccaagc
     1141 tcgtgtactg cccaaaaaag ttagacattc tatttagaac gaggattgag ttctgtattg
     1201 tacaaggctc ggtcctttta gagtcagctt aaggctggct ttttcaatca ccaaagtgtc
     1261 agaatgtttt gacaaatgaa cacaaataat gatataatat gcaaaagcta ggaggtggta
     1321 ggatgattga aaaaatggaa ctgggggaat tttacaagga attacgtttg gcgagaaagc
     1381 tcaagcagtc agatgtggct tgtgacgggc taacagcttc tcagttgtcc aagtttgagc
     1441 tagggcagtc catgttgtct gctgataagc tcatattagc catccaaggg atcaatgtga
     1501 cctttgatga gtttgggcac aagctcaaca actatcaaga atctccacat atgcagattg
     1561 gtagaaaggt tgtggatcgc tttgctcatc aagatatagc tggcttagag caactgttgg
     1621 aggaagtcga gcaagaacag atggcagaga cttatcgtcg tttgaatgct attgtaatca
     1681 aagatgccat ccactcacta gataaaagct acccactagc agaggaggat agcgagtttt
     1741 tgaccaccta tctctatgct atcgagtctt ggacctggtt tgaactctat ctcttttgca
     1801 atactctgcc cttcttgagc aatcaagatc tgatcttttt atcaacctcc ttactcgaaa
     1861 aatccaaaga atttaaagag ttagtacaca atcgattgta tatgaagcaa ggactcttaa
     1921 atatcttatc agaactcatg gagcgaaaac ttttcttata catcccaatc ttcgaagccg
     1981 agttggagag catgttgcgt ccgtacgatg tttttgaaaa agtatcgtgg caatttttaa
     2041 agaagatgag tgtctttctt caaacaaagg gaagcaatca aaaagagatt gaacgcttta
     2101 cccaatctct gcaggtatta gaaaatccac aattaacatc cctttttgaa ttgcgtttgc
     2161 agcaatacaa aaagcttatc gattagttag aaatggcaaa ataataataa tctcagcaac
     2221 gatcgtcaat aatgttaaaa cttgtttctt catattactt ccctcctcat tagtaataac
     2281 tttattatac cagggaaata atcaaatcta ccaaaatcgc aaatctgaaa tttctataag
     2341 aaaaaatatc aaatatgcga ttttctaaaa taagccaatt tccgtgttat actgtccttg
     2401 taaaacattt gaagcaaatc ctaggtcgca gaagtggttt acaaatgaag ataattgaag
     2461 gagtgtaaaa gatgttaaat ttacaatttg cagaaacaat ggaattgaca gaagctgagt
     2521 tggagacagg ttatggaggg gaatttggga ataatgctgt tatcccagcc ggtgcttggg
     2581 gaggtttagg aacgtcttgg tcaatcacta atttctggaa gaaatatttt aaccatgatt
     2641 cttccactgt taatcgtcgc cattattgat attcagagtc cttgcctttt tcttgggtag
     2701 ggactgtctt tatttcatag tataggagaa aatagaatga aaaagataat ctcacaccgc
     2761 tactttatta tagtttttct actagttatt gctgaccaga agttcagtgt tttagtttta
     2821 cgcagcgacc ttgttgctgg gctatctgac tttgcctatt atctgtcgga tatgatgttg
     2881 aattttcttg tggttttatt tgctcttatt gctatgattt ggtcggggaa atggcagaaa
     2941 atcaatagta gaaagtttaa aggatcctat cttttctatt ccttcctagc tctgcttgct
     3001 tttgttgctt ggaattttgt cacctttttt cttttcccac ctactcgaaa tgaaatttct
     3061 tatcaacatg ctgctcctac ttttacagga gctacggcat ttttgatgta ttttttttat
     3121 cctgtgattg caggtcccat ttttgaagac atgatttatc gtggattagt gatgactgct
     3181 ctggaaaaag gaaagaaatg ggggctagat gtacttggtt ccgctgtttt atttggggtc
     3241 tcgcacatta gtaatcacgg ttgggtcttg acagactttg tcttctatat gggtggaggt
     3301 cttatatttg cagtcttatt tagaatgaca aagtcaattt attggcctat tggactgcat
     3361 atagtctaca atggcattgg tcagcttttg atgttactgt aattttggtt gttagtagta
     3421 tcgcggtcta tccttgggga aagattccca tttgaactta agaaggagtt gtgatgaaag
     3481 tatttcttca aaatagagat tttaggcaat taactatcaa ccagtggatt tcaacgcttg
     3541 gggatacgat tttttatctg gcctttctga attatgtggc agatgcgtct tttgcacctt
     3601 tgacgatttt actcattacg atttcagaaa cccttcccca aattttacaa atctttctgg
     3661 gagttttggc agattttcaa catcatcgtg tcttgaaata cacagtcatt agttttgcaa
     3721 aatttttgct ttactctatc gtttctttat cactttcagg gcagtctttc tccttgttgc
     3781 tagtagcatt tatttgtctg cttaacctct tgtctgacac attgagttac ttttcaggag
     3841 ccatgctcac tccgattttc attagaatta ttgggcaaga ccatctggca gaagctattg
     3901 gctttaaaca gtcaactgtt agtttagtga aaacaatcag taatatccta ggaggagtct
     3961 tactaggcat tctatccatc cagtttattt ccttactgaa cgctcttacc tttttaatcg
     4021 catttttagg tatcctcttc ataaaaactg acctcttgaa agtagaaaaa acgattagct
     4081 atcaagaagg actctctgta aaatcctttt gccagcattt gctccaatca tcaaaattga
     4141 tatggaatat gaataaggtg ctcttggttt tgtttattat ctctactagt caagcagtga
     4201 taaatgttac ggttcctatt tccactctat ttttaaggaa ccagcccttt ttgaatttac
     4261 aaacaggtca atctcttgcc ttgctatcca cttttgaact gtcagccctg attgtcggaa
     4321 gccttgtaag tggctatctg caacatacca tttccataaa aacagctctc tatgcctcac
     4381 ttgtcatcca gttgcttctt ctagtaggat ttgccacagt tcgttttgac tggattctca
     4441 tctttagtac cttggatgcc tttttcgcag gtgttctctc tcctagattg caagaactcg
     4501 tttttaaaca aatacctgag gagtcaatgg gagcagttca atcctctatc ggtgccatta
     4561 cggttgtttt acctagctta tttacaatag ctttggtaac cattgctact agctttggaa
     4621 ctctggcagt tagctttgtt ttattgctat ttcttctagt tgcctttgtt atgcttctga
     4681 atattcgtga aagtatttag tggagaattt ctataatata tgtttgagac tggattgcca
     4741 gtctttttat gatggtcaaa atcaacagac tttttctctt ttctgaatgt gttatagtag
     4801 actgaatcta aaatagtacg aaacaattgc taaaacattt atagaaatta attttacttt
     4861 cccaatcgat ttgttctcat cttatttcaa tctgctatat aatagtccat gctgtggctg
     4921 gattcttttc agcctacttg tactcttcga aactctcttc aaaccacgtc agcttcactt
     4981 tgccgtagta cggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
     5041 gctgacttcg tcagttctat ccacaacctc aaaacggtgt tttgagcaac ctgcggctag
     5101 tttcctagtt tgctctttga ttttcattga gtattattaa gacaatatga ggagaaagat
     5161 gaaagaaaaa ggattttagg agggggcgca ggcagccatg ccaacggctc ttggctatgt
     5221 cagtatcggc ctggcctgtg gaattatcgg tgcgccctat gtgacacttg ttgagatggg
     5281 cttgatgagt ctctttgttt atgctgggag tgcccagttt gccatgttgg cactgattgt
     5341 ggttcaagct cctgtggcag ctattgctat gacggttttt ctaatcaact tgcgtctctt
     5401 tttgttgagt ttacacgcat cgacttattt ccgtcatacc agtctttggt acaatatcgg
     5461 tatgtctagt atcttgacag atgagaccta tggcgttttg atgggtgaat tggcccatac
     5521 agacaaggta aatcctatgt ggatgcacgg gaacaatctc aacagctatg tggcttggtt
     5581 tgtggggaca gtagtcggaa cggctctggg tggcctgcta ccaaatccag aaatctttgg
     5641 cttggatttt gccctggttg ggatgtttat tggtattttt gcttcgcaat ttcagattat
     5701 gcaaagacgg attcctgtcc gcaatctgct cattatccta gcagttgttg cggtgtcctt
     5761 ctttttgctc ttgacagtgg tgtctcagtc actagctgtt ctgtttgcga cgctacttgg
     5821 ttgtagcatg ggggtggttt tagatggtca gtaagtatct tttattagca gttattttct
     5881 ctggtcttgt gacctggatt ccccgtatga ttcccttcat cttggtcaag cataagggcc
     5941 tgcctgcgat tgttgagcgt tttttgaagt ttttgcctgt ttccattatc tttgccttga
     6001 ttctttcaag cgtagtgaca ggtaaggttg ggagccttcc tcaaattaaa tggctagact
     6061 tcttagccgt ctttccaaca gcttgggtag cctttcgcta ccgcaatcta gtcggaacag
     6121 ttctctttgg agtggtcttg attgccatct tgcgtttggt cttttaaatt acccataaaa
     6181 aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt
     6241 ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg
     6301 ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg ctcagggggt gctaagaaag
     6361 aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaggccat
     6421 ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt cgcgctatct
     6481 ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca ggtgtctttg
     6541 ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac
     6601 gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtcgtga
     6661 agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg
     6721 ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc
     6781 caactatcct taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg
     6841 gacaatttga ctacaagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag
     6901 gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac
     6961 ttcttgctca gggtcaagat gagttgaaat catttgtaga caaacgcatt aaagaactct
     7021 acaaagacgg aacgcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg
     7081 cagaagctga tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc
     7141 tcagttttta gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa
     7201 atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa
     7261 tcaaaaaatg gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt
     7321 gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca actgttaacc
     7381 gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa
     7441 ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg
     7501 gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa
     7561 acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag
     7621 gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa
     7681 tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg
     7741 gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa
     7801 atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat
     7861 cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga
     7921 aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg
     7981 cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt
     8041 accacacaga tgacgtgaaa aaagttatcg aagaatcatc agatggtttg gatcaaccag
     8101 tttggtaata agaaacaggg aggtgggaga gaaaattcca cctcttgctt ttgtatagag
     8161 tatagattgt aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta
     8221 gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agtccaacat tattttgagg
     8281 ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag
     8341 tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga
     8401 gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct
     8461 tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg
     8521 atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca
     8581 agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac catgatgatt
     8641 tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag
     8701 ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac
     8761 aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag gggattgtga
     8821 cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggtgttg
     8881 tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc
     8941 gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct
     9001 tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt
     9061 tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc gagccagcgc
     9121 ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg
     9181 cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc
     9241 tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa ttatactata
     9301 ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg
     9361 agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag
     9421 gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc ggtctaggaa
     9481 atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc
     9541 atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat caagttagat
     9601 cagatcgatg tgacttttca ccaaaagaag agaaccatta cagcggttaa ggatgtgacc
     9661 attcacatcc aagaagggga tatctacgga atcgttggat attctggagc aggaaaatca
     9721 acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat taccattgac
     9781 gacgatgtga tttttgacgg caaggtgacc ttgacggcag agcagttgcg tcgtaaacgt
     9841 caagatatcg gaatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag
     9901 aatgtagcct ttgcccttaa acactctgaa ctcagcaagg aagaaaagaa ggctaaagta
     9961 gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta
    10021 tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc
    10081 ttgatttcag acgagtcaac ttctgccctt gatccgaaga caaccaagca gattttggcc
    10141 ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcttgattac gcatgaaatg
    10201 cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca tttgattgaa
    10261 gagggtagtg tgcttgaaat cttctcagac cctaaacaac ctttgactca agactttatc
    10321 tcaacagcca caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa
    10381 cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggatcttc aacagacgag
    10441 ccacttttga atgaattgta caagcattat caagtaatgg ctaatattct ctatgggaat
    10501 atcgaaatcc tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa
    10561 gcagcgttgg caggtgccca agaagccatt cgtcaagcag gcgtacagtt aaaagtattg
    10621 aagggaggac agtaagatgg aatcattgat tcaaacctat ttgccaaatg tctataagat
    10681 gggttggtct ggtcaggcag gctggggaac agctatctac ctaaccctct atatgacagt
    10741 tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac
    10801 agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc
    10861 aatttttcgt gcgattccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt
    10921 gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt
    10981 tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga
    11041 ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg
    11101 tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc
    11161 tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa
    11221 ccgctacaat cacgatgtga ccatcttggc aaccattatt atcattttga ttatctttgc
    11281 aatccaattc ttgggagatt tcttgactaa gaaattgagt cataaataaa aagagccgcg
    11341 tggctctttt taactgatca gattttctgt gcaaattttt tactcaaggc ttgtccaatc
    11401 aaggcaccca ctagggctcc gatgacaata cttgcgataa atagaaggac agttccaggg
    11461 tttggagcga ccatgatacg gtcgatatat tcttgggatt ttcctcttgc cagaagagta
    11521 gccatatagg ctttgggcgc aatccacata agcaagattg gtcctgttgt actaaaggcg
    11581 aaaataatga aagaaaggaa gttctttgtt ttgtccttgt attttcctaa atgagctact
    11641 tcatctgcta ggaggccaca gataattcca ggaaggaagg aaccagcacc gtgtttagtt
    11701 cccaagaaaa agagggcaat gacaaggccg atagtggtaa tggctccaaa gcgcggaact
    11761 tttgcgacta ggatcatata gacgctaccg ccgacaaggg cagtaaaggc aggcgcataa
    11821 aacatgtttc cagtttggtc aaagagattg cccaaaagga caccaatccc catgcagagg
    11881 aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt tcttcatgaa ttgtctcctg
    11941 ataatttttt cacaattctc attgtaccac ggtttggtgg gattgtaaat ggatactaga
    12001 agtttttgaa aacgcttgaa atatgatata atggtttcat agttattttt aggggaatat
    12061 catgggtaga tttttagact ttgtctttaa tcgtttcttt ttagggatga ttgcgacagc
    12121 cttcttttgg ctattaactt tagcaggagg gattatcctt ggtctagcgc cggctagtgc
    12181 caccttgatg agcttatatg cagaacatgg ttatagcttt cgggaataca gtttgaagga
    12241 ggcttggtct ctttacaagc aaaattttgt ctcaagcaac ctgattttct atagcttttt
    12301 aggtgtgggt ctagttttga cctatggttt gtatctcttg gtgcaattgc ctcatcagac
    12361 cattgttcat ttgattgcga cccttttgaa tgtcctagta gttgccctga tctttttggc
    12421 ttatacagta tctttaaaat tacaagttta ttttgccttg tcctatcgaa atagtctcaa
    12481 attatccttg attggcatct ttatgagtct agcagctgtg gccaagattc tccttgggac
    12541 tgtgctactt gtagcaattg gttattatat gcctgccctg ctattttttg taggaattgg
    12601 gatgtggcat ttctttatca gtgatatgtt ggaacctgtc tatgaaatca tccatgaaaa
    12661 attggcgaca aaatagaatg aagcagtttt ggctacatac gcttctaaga acctatagtt
    12721 cagtgatgat cattatcatt gcgagttttg caatcttact ctcttacgct gactgggatt
    12781 cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac tgctagaaca gtgagtgaaa
    12841 ttgaatatta ccatagagag tcaacccaga tagctcaggc tttagttgaa aaccaagctc
    12901 gtattgaggg aatctataaa tactttagtc ttagcatgcc agactatttt tactggcaat
    12961 tagagcggaa agcttcgcct tatatatcag tctctctgta tgaaaatgtt gatgacctct
    13021 atgttcgaaa tgattttgta actggagtgg ccattgcttt tcaagattac aaggaagtct
    13081 atgtttctac taaagacaaa cgtagtggag aaaaaatcag ggctgaggat ttcaaaccag
    13141 caggaaatag ttttgccatt ccggtgtcag atccagtgtc agatcaagat ttaggagtga
    13201 tttacatctc cttggatcct gctgttttat accatgccat tgataatact agaggtcata
    13261 ctccgatggc agtaacagtg acctcacctt ttgatacgga gatttttcat attggtgaga
    13321 cagttgataa ggagagtgaa aattggctag ttggcttaac ttctcatgga tatcaggttc
    13381 aggtggcagt tcctaaaaac tttgttttac aaggaacagt gactagctct gctttgattg
    13441 tgggtttgag ccttctcttt attgtcattc tttatctgac tttgaggcag acttttgcta
    13501 attaccaaaa gcaggtagtg gatttagtag aatccattca agtcattgct caaggcgaag
    13561 aggggcgtcg gattgacatt tccgagaaag atcaggaatt actcctaatc gcggagacga
    13621 ccaatgatat gttggatcga ttggaaaaga atatccatga tatttaccag ttagagctta
    13681 gtcaaaaaga tgccaatatg cgagccttgc aggcgcaaat caatcctcat tttatgtata
    13741 atacgctgga gttcttgcgc atgtatgcag ttatgcagag tcaagatgag ttggcagata
    13801 tcatttatga attcagtagt ctcttgcgta acaatatttc cgacgaaaga gagaccctcc
    13861 tcaaacagga attagaattt tgccgtaaat acagctatct ctgcatggtt cgctatccca
    13921 agtccattgc ctatggtttc aagatagatc cagagttaga gaatatgaag attcccaagt
    13981 ttaccttgca accgctggta gaaaactatt tcgcgcatgg tgttgaccac aggcggacag
    14041 ataatgtgat tagcatcaag gctcttaaac aggatggttt tgtggaaatt ttggtggtcg
    14101 ataatggtag aggaatgtcg gctgaaaagt tggcaaatat ccgagaaaaa ttaagtcaga
    14161 gatattttga acaccaagcc agctacagtg atcaaaggca gtctatcggg attgtcaatg
    14221 tacacgagcg ttttgtgctc tattttggag accgctatgc cattactata gagtctgcag
    14281 agcaagccgg tgttcagtat cgtattacaa ttcaagatga gtagaaaggg agaaaatgta
    14341 taaagtatta ttagtagatg atgagtacat ggtgacagaa ggtctgaagc gtttgattcc
    14401 ctttgataag tgggatatgg aggttgtcgc aacagccagt catgccgatg aagctctaga
    14461 atatgttcag gaaaatcctg tcgatgtcat catttccgat gtcaatatgc cagacaaaac
    14521 agggcttgat atgattcggg agatgaaaga gatcttacca gatgctgcct atatcctgct
    14581 ctcaggttat caggagtttg attatgtaaa aagagcaatg aaccttagtg tggtggacta
    14641 tttggtcaag cctgttgata aggtagagct gggaaatctg ctggagaaga ttgcaggtca
    14701 gctcggcgag agagggaaga aaagtcagac tcttagtcaa gaattagacg aggctggatt
    14761 tgttagttat ttaggggata aggagaattg gtggataggt ctatccaagg aaaaacaagg
    14821 ttccttcacc attccctact atgtcttggg tcaagactgg cagattttca tttctggcca
    14881 acccttagat ggcttagtcg ttactccctt tgaagctccc tatcaagaac actttgaacg
    14941 ctggaagctg aatgctgaga aaaccctctt ttacggttct gtaaatctgc agcagtctga
    15001 gagtctcttt gcctattacg aaccgattta tagggttatc attcagggaa atctcaatca
    15061 aatcgtagaa gagttaaatc tcttggagaa ggtagttctt gaaaatacgc cgcgtgttcc
    15121 gattactaaa cagcttttta ttcagtttgt catggatgtt ttccatttat ttgaacatct
    15181 caaagctgat gacctgacag acatcgttaa aaccattcat gctattcaat ccttcgatga
    15241 attggttcct tatatcaagg aaactctgac cagctttttc ggtcaatacc gtatgaatga
    15301 aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac caaaaagagc tttccctcaa
    15361 ggatatcagt aaggctctct ttatcaatcc tgtctatcta gggcagttga ttaagcgtga
    15421 aaccgattcg acttttgcag agttactaaa caaacaacgt attaaggctg cccagcagct
    15481 cttgctttca actagtgaca gcatcgaaga tatttgttat gctgttggtt acagtaacct
    15541 tggatatttc tataaagttt tccgaaaatt gtgcggaaaa tcgccaaaag cctaccgaaa
    15601 acaggtagaa actatactat aagatttgta ttcctttaca aaatgtgcta taatattatc
    15661 aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc
    15721 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
    15781 tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
    15841 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
    15901 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
    15961 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
    16021 tggtttacaa gatgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat
    16081 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
    16141 cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa cagaagagct
    16201 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
    16261 atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat tagtttgagt
    16321 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
    16381 attgaggttc aaaagattca tatcaaggat ttggtcaagg aaggcaaaaa tttctacgaa
    16441 atggaccatc cctatgttgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
    16501 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
    16561 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
    16621 ctaacagcca agcaatacag tcaacgcttt ggctttcctg tattggctga ctttgaaatg
    16681 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
    16741 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
    16801 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
    16861 atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
    16921 agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
    16981 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
    17041 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
    17101 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
    17161 cacgtgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa
    17221 tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata atgatgatac
    17281 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattatcc tctttttgac
    17341 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
    17401 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
    17461 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
    17521 cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag
    17581 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
    17641 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
    17701 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
    17761 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgca agaacagtcg
    17821 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
    17881 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
    17941 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
    18001 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
    18061 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
    18121 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
    18181 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
    18241 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
    18301 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
    18361 attctacaaa aaattttgga aaaatgcaag agtattttga aaaaagatag aaaatttaca
    18421 aagaaaatct gaaataactg ttatgatata gaggattgaa actagaatag tacacctctg
    18481 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt
    18541 tcatttcact atagtaaggt gcagcaggat aaagaaaaac cgagaagttt ctttctcgga
    18601 tttgcttatt atgaggttcc tattttctat gctccaagag ttgattgatg tgatctactt
    18661 ttttagcctc tcttttatag agaatagccc agatgatgag atagacaatc gcaaactcga
    18721 taatgagctg gaggtagaaa atccagtgga aagggaacca accagcaaga gttgctagtg
    18781 ggacaaagcc agccagcata aggaagaaat gagtcagagt ggcacgaagc atgctccagt
    18841 cacggctaaa taagcggttg ccaaagttga agagcatacc gatggttgcc cagataagtg
    18901 tgcagtagag caagaccagg gcaccgtgaa cctgatgctg atccatcact tggccgatga
    18961 gagagtaggg atttagtggt gcgtaggtat ttggtgcata aatgagtgaa aagaggatag
    19021 agaggatgag gccgataaga acaccggtag ctgcatcgtg aaatacttgt tttttcatag
    19081 ttctaatttc tccttgatgg tttttagata acggcgtgaa gagtaggtga agctttcgtt
    19141 tttcaagaaa atttctacca gaccgtttgg cgtgagcttg aggtgagaga tggaatcgat
    19201 attgatgatt tctgattggg aaatttggat aaaattggtt ggcaagagtt taagaacctg
    19261 atagagtcgc aaatcaatgc tgtaggtctg actcgcggtt tctgctagaa ccttccgatt
    19321 ctcgatatag aagcgctgaa tcttgccaat ctcaactaga tagacctgat catcgatttt
    19381 tcctttgatt ttttctcttt ggtccagatt ttctgcgaac tcgatgactt tctggacttt
    19441 ttcggtttct tgaggtgctt ggacaatcag cttttcctcc tcgtaagtct cactaatctg
    19501 tagttctact ttcatagttt tctctccttt tcagttatac aaggttgtga tcacttcctg
    19561 tatatcctta ttaaacacta ttttatagcc catggcaagg aaccttgtct atgtggaggg
    19621 attgggctcc tatgtggtgg agcttttctg ttctttctga aatatggtat aatagcacta
    19681 atcaatttct aggaaaatag atacggaaag gggctgaaag aactagggga acagttggaa
    19741 ttagaaagtg ataggtatga aaagtggcgt tgaagctgaa taagtttata aagcgtttga
    19801 atgaagaaat ggaaagtaaa taagttgacg atgaattaca aaatagattt tatctacaat
    19861 ttgtatcttt caaatcattg atttgaattt tagatttaat catgttacaa ttaaaactga
    19921 aatcaaatag aagaggaaaa tgcaaacgtg ggcacactat tagcaacaag attaaaaaat
    19981 agacggaaag aattaaaaat gtctcagcga gaactagctg aaggtatctg taaacagggg
    20041 caaatcagtc gattagagag cggagagttt acccctggag cggatttcct gaatgccctt
    20101 gctaagaagt taaaagtcag tatggattat ttttttgatg agcaggttgt agagaaagtt
    20161 gaggagttat cagaatttaa gaaattagca cagacattta ttacaaatcg caattatgag
    20221 tctttgaaat atatatatga attggagaat gtaaaagctc accgcctatc tttagcagat
    20281 aaaatctaca tggaatggat aaaatctctg atagattttt atttttacgg acagaaagaa
    20341 gatgcgattg tacgattaga gggggtatta tcacagttaa gtgtatctga tttgaactat
    20401 ctccaagttt caaacaccct attcaatttt tattatgata ttggagattt aggtcgtttc
    20461 aataaaattc gtgaaaaact agagtatcaa gtaaatcacc tcaatttgag tacaatcgaa
    20521 gagttagaac tatctattaa gtttaactac aacgtttgtc gttatctatg gttacagaaa
    20581 aatattgaag aagctattac taaaattaca gctactataa aacaatgtaa ggcttacaga
    20641 acgaattatc ttttggctga tttgtactta ttgatgggaa atgtaagtga aaatttttct
    20701 tctaaaagtt cggtgaaaga atattttgag acggcatatt ttctatacaa acttgaggag
    20761 aacatgtcaa tgactctgaa agttgagcat tacattgcag atataacaga ataatgaata
    20821 cggtgttcaa gtgagcatcg tttttcaaac ctagttcaga tacaaaaaag tatcaaacaa
    20881 aaaaaaataa aaaaacatta taaaaacaat tgacaagcta attttgaagt gataaaataa
    20941 atgcaagaaa acaaaaggag aggtatatga gaagtttgtt taagaaaata gttgctgtat
    21001 tagttattgg cttaattctg ttaggaattg cgagaacacc tcaagttcat aagatggcta
    21061 gagggattga tcctggtcct gcgaatttta tttagaaatc aatttctact aattgagtac
    21121 taattgagta ttaatgggta aaaagattgt atggataaga aaaatttact tgtattggtt
    21181 actggttcgg taggtgccag taa
//
LOCUS       DAVKUR010000036        21175 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKUR010000036 DAVKUR010000000
VERSION     DAVKUR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21175
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.036"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            65..2190
                     /gene="blpA"
                     /locus_tag="VW749_001459"
                     /pseudo
     CDS             65..2190
                     /gene="blpA"
                     /locus_tag="VW749_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            2201..3562
                     /locus_tag="VW749_001460"
     CDS             2201..3562
                     /locus_tag="VW749_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0175482.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGIFKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            3619..3774
                     /gene="blpC"
                     /locus_tag="VW749_001461"
     CDS             3619..3774
                     /gene="blpC"
                     /locus_tag="VW749_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0175483.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(3818..5158)
                     /locus_tag="VW749_001462"
     CDS             complement(3818..5158)
                     /locus_tag="VW749_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0175484.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(5172..5909)
                     /locus_tag="VW749_001463"
     CDS             complement(5172..5909)
                     /locus_tag="VW749_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175485.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(5914..6252)
                     /locus_tag="VW749_001464"
     CDS             complement(5914..6252)
                     /locus_tag="VW749_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175486.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6528..6857
                     /locus_tag="VW749_001465"
     CDS             6528..6857
                     /locus_tag="VW749_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0175487.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7025..8074)
                     /locus_tag="VW749_001466"
     CDS             complement(7025..8074)
                     /locus_tag="VW749_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175488.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8071..8802)
                     /locus_tag="VW749_001467"
     CDS             complement(8071..8802)
                     /locus_tag="VW749_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175489.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            8870..9280
                     /locus_tag="VW749_001468"
     CDS             8870..9280
                     /locus_tag="VW749_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0175490.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9290..9577
                     /locus_tag="VW749_001469"
     CDS             9290..9577
                     /locus_tag="VW749_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175491.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            9739..9978
                     /locus_tag="VW749_001470"
     CDS             9739..9978
                     /locus_tag="VW749_001470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175492.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10300..11436)
                     /gene="dnaJ"
                     /locus_tag="VW749_001471"
     CDS             complement(10300..11436)
                     /gene="dnaJ"
                     /locus_tag="VW749_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0175493.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11641..11895)
                     /locus_tag="VW749_001472"
     CDS             complement(11641..11895)
                     /locus_tag="VW749_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175494.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(12008..13831)
                     /gene="dnaK"
                     /locus_tag="VW749_001473"
     CDS             complement(12008..13831)
                     /gene="dnaK"
                     /locus_tag="VW749_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0175495.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14311..14835)
                     /gene="grpE"
                     /locus_tag="VW749_001474"
     CDS             complement(14311..14835)
                     /gene="grpE"
                     /locus_tag="VW749_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0175496.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(14862..15896)
                     /gene="hrcA"
                     /locus_tag="VW749_001475"
     CDS             complement(14862..15896)
                     /gene="hrcA"
                     /locus_tag="VW749_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0175497.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16060..16497)
                     /locus_tag="VW749_001476"
     CDS             complement(16060..16497)
                     /locus_tag="VW749_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0175498.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            17177..19510
                     /locus_tag="VW749_001477"
     CDS             17177..19510
                     /locus_tag="VW749_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0175499.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19523..20986
                     /locus_tag="VW749_001478"
     CDS             19523..20986
                     /locus_tag="VW749_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0175500.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFKDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            20986..>21175
                     /locus_tag="VW749_001479"
     CDS             20986..>21175
                     /locus_tag="VW749_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV0175501.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         6737 a         4309 c         3942 g         6187 t
ORIGIN      
        1 taataaaata tgaacttatt tttatggcat aatataccta tctactatat gaaaggaatt
       61 gccaatgact tcttataaac gtacatttgt tcctcaaata gatgcgagag actgcggtgt
      121 tgctgcctta gcctcgattg ctaaattcta tggttcagat ttttctctag ctcacttgag
      181 agaacttgca aagaccaata aagaagggac gactgctctt ggcattgtaa aagccgctga
      241 tgaaatgggc tttgaaacaa gacctgttca agcagataaa acgctctttg acatgagtga
      301 tgtcccctat ccatttatcg ttcacgttaa caaagaagga aaactccaac attactatgt
      361 tgtctatcaa acaaagaaag actatctgat tattggtgat cctgaccctt ctgtaaaaat
      421 cactaaaatg tcaaaagaac gctttttctc tgaatggact ggagtagcta tttttctagc
      481 tcccaaaccc agctatcaac cccataaaga taaaaagaat ggtctactaa gcttccttcc
      541 tctgattttc aaacaaaaat ctctcattgc ttacattgtt ctctcaagct tattggtcac
      601 tattatcaat atcggtggtt cttattatct ccaaggaatc ttagatgaat acatcccaaa
      661 tcagatgaaa tcaactttag gaatcatctc agttggtctg gttatcacct atatcctcca
      721 acaagtcatg agcttctcca gagattaagc attgatgtga ttttatccta tattcgccat
      781 atttttgaac ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacgg
      841 ttcacagatg ctaactctat tatagatgcc ttggcttcta ccattctttc tctttttctg
      901 gatgtttcta ttctgattct tgtagggggc gtcttactgg cacaaaaccc taatctcttc
      961 ctcctttctc ttctttccat tcctatatac atgttcatca tcttttcttt tatgaaacct
     1021 ttcgaaaaaa tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc
     1081 gaagatatca acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa
     1141 aatatagaca gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct
     1201 attttacaaa cgagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg
     1261 tttggcgctc aattagtcat gtcaagtaaa atttctatcg gtcagctgat tacctttaac
     1321 acactttttt cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc
     1381 caatctgcga aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt
     1441 caagttcaag aaaaccctgt tcattcacat tttttgatgg gcgatattga atttgatgac
     1501 ctttcttata agtatggttt tggacgagat accttaacag atattaatct cacgattaaa
     1561 caaggagata aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa
     1621 atgattgtca atttctttga accctacaaa gggcatattt ccatcaatca tcaggatatt
     1681 aaaaacattg ataaaaaagt cttgcgccgt catattaatt acctacccca acaagcctat
     1741 atctttaatg gctctatttt ggaaaactta accttgggcg gtaatcatat gattagtcaa
     1801 gaagatattc taaaagcttg tgaagtagct gaaatccgtc aagacattga aagaatgcct
     1861 atgggctatc aaactcagct ctctgatgga gctggtctat caggaggaca gaagcaacga
     1921 atcgctctcg ctcgtgctct tttaactaaa tctcctgttt taatactaga tgaagctact
     1981 agcggtcttg atgtcttgac tgagaaaaaa gttatagata atcttatgtc cctaactgat
     2041 aaaaccattc tctttgtagc ccatcgtctc agtatagccg aacgaaccaa ccgtgtcatt
     2101 gttcttgacc aggggaaaat cattgaagtt ggtagccacc aagagttaat gcaggcgcaa
     2161 ggtttctacc atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag
     2221 aagcgtcgag ttttatcaga gacgttacca taactatgcg acagtgttaa ttatacctct
     2281 ttcattacta tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt
     2341 cacttcccaa ggagaaatcg cccctacaag tgtcatttca tctattcagt caaccagtga
     2401 taatcctatc cttgctaatc atttagtggc aaatcaagta gttgaaaaag gggacttact
     2461 catcaaatac tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca
     2521 aagacttgag aagcaaaaag aaggacttgg aattttcaaa caaagcttag aaaaagcgac
     2581 tgatcttttt tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa
     2641 acaatcccat gatattgaac tgggtatctc aaagactaac actgaagttt caaatcaagc
     2701 taatcttacc aatagcagtt catcagccat cgaacaagaa attacaaaag ttcaacaaca
     2761 aattggagaa tatcaagagc tgagagatgc tatcgtaaat aaaagagctc gcttaccaac
     2821 tggcaatccg caccagtcaa ttttaaatcg ttatcttata gcctctcaag aacaaacaca
     2881 aggaacggca gaggagccat ttttatctca aattaatcaa agtattgcag gtctggaatc
     2941 atctatcgca agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa
     3001 tagtttagca accaaaattg aagtactccg cactcagttt ttacaaacag cctcacagca
     3061 acaactaacc gtggagaatc aattaacaga attaaaagta caactagatc aagcgacaca
     3121 gcgcttagaa aataatacct taaccgctcc aagtaaaggt atcgttcatc tgaacagcga
     3181 atttgaaggt aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctgtcat
     3241 cacagataca agagaagtac taatcactta ctacgtatct tctgactatc tacctctact
     3301 agataaagga caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcaccaccat
     3361 catcggccaa cttcagacaa ttgatcaaac tcctaccaga acagagcaag gaaatctctt
     3421 taaattaacc gctcttgcaa aactatctaa cgaggatagt aaactcatcc aatatggctt
     3481 acaaggtcgc gtcactagtg taactacaaa gaaaacatat tttgattatt tcaaagataa
     3541 aattttaacc cattctgatt aattttcaga taacactcta taactattta ttatcttatc
     3601 aaaaaggaga atcataacat ggataagaaa caaaacctaa cttcatttca agaactaaca
     3661 actaccgaac tcaaccaaat tataggtgga ggatggtggg aagatttctt atatagattt
     3721 aatataattg aacaaaaaaa tacaaaagga tttcatcagc caatacaact ataaaaaaac
     3781 aagaccaaga gaacgcactc tcggtcttat tttttcttca ttctatatgt attacagtaa
     3841 gtacctgacg aaaaacgtga tcttggcagg tggtattgag actggtattg ggatgacttt
     3901 ccacaatttt cataacggta tagagaccaa ctcctctctc ctccccttta gaacttgctc
     3961 caaaggagaa gatttcagaa atatcgattc cctcttcttt gatggaattt tcaatgataa
     4021 aggtctcctg tgctccattt ttaaaaaagg caattgaaac atgaggttga caggcttcta
     4081 cactagcttc aatagcgttg tcacaaagga tagacacaac ggttagaaaa tcaagtagac
     4141 tcatcccctc tacctgaatc tcctctggaa cttcgacatt aaagacaatg ttcttatctc
     4201 tagcttttat aaattttcca gctaggagac ttttgagggc acgatcccga acattcacca
     4261 atcggccaag gtcatattta ttgtcctgca atttctgact ggaatccctt aagaccgagt
     4321 cgtagatctc ttttatctgc tccatatcct cctcttcaat gcccaaacgt aagctggtta
     4381 agaggttagt gtagtcatgg cgaaaactcc gaatttcctt gtaaagttcc tctatatgcc
     4441 gactatagcg ttccatatct ctgtagcgca aggtctgctc ttggttcagt tcctcctgaa
     4501 gtttttcctt caaataggta tccaatttct tgataccccc cataaaaaag agtaggtaaa
     4561 acactaggat gagatggcga acagtcgttg attgaatacc ttgttcatat tcaaggtaag
     4621 atagactttg catcactaga taataagccc ccattgccca gttaatctta gtaagagact
     4681 tttgaaaacc tgtatctaga aactcccttc tcaatctagt gaaatcatag tctaaccatt
     4741 tcaaaaagac taaaactatg aagcaaacga atatcataat caataaaaag ataggattgc
     4801 catccccatc tacaattcct tgccccaaaa atggaagcac aaaataggaa acacctctgt
     4861 aaaagagctc tactaatatc attgggaaga gaccataaaa aataaggatt tttttaggaa
     4921 gccctcttaa caataagaaa gatagaccta taccgaacaa aggttctata aaataggaca
     4981 aatatttact tacagccaaa aattgaaaag tcgtaaaaat gatccctaga agaaatttca
     5041 gaagaaaggc cttaaaaatc ctctcgaaag taagatcaat tccatccacc ttaaagaaga
     5101 tgacaatttc tagtccatta gtaacaagtg tatacaacaa tatccaagca atgttcataa
     5161 attctcctag ctcagtgtaa tttattgatg gcctcagaca cttccctgac cttataacgg
     5221 gcgattagac aacttccacc attgggaaag aaaagcagtt tttctttctt atccaaatgc
     5281 accacatttg caggattgat gagaaaagag cggtggcact gcaagagacg gggctcctgc
     5341 ttgaaaacct cctctaaact cgctgtaaat tccagcctgt ctgtcttggt atagagaata
     5401 acacgatggg ctctgggcga cgtttcgaga tagtaaacct ctttaaaagg atactgaaat
     5461 tgggcaaatt ttgatttaaa gtaaaagcaa tcttccgcca gacttttact atcttgacta
     5521 ttggcataga ggagggctgt ctcgatccga gattcaaact cctctgctga caaggcctta
     5581 tcaatgtagt ccaaagcaga cacttggtag cgaaaagaca ggggcataaa ctccgagtga
     5641 gtcgtcacaa agacaatcag ggcataagga tcccgatccc gaatctttct agccacttcc
     5701 agtcccttca tctcttcatt tcgaatctca atatccaaaa agaatagctg atgggccccc
     5761 ttctcatgca cttcagccag cagttggtcc ggcttgccaa atacctcaaa agagctagga
     5821 atgatatgat gtgctttcaa aagtttctca atcgtcgttt caattctagt ctgttgggaa
     5881 aaatcatcct ctaaaacaaa tattctcatc ttcttactct ccctctttca accatttttg
     5941 acgaatttct ctatagcgac gtctggcata cttgacagcg tattgacctt cttctccgag
     6001 aaaaaggatt ctttcttgaa aatcaatcga ttttaattta tcaagattaa ccaaacaatt
     6061 tcgatgacat ctcatcaagg tttccccaca ttggttctca agattactta aattttgaag
     6121 catattaaaa ctagcttctt ctgtaacaat ctgtacggta tgggctttag ttggatgtgt
     6181 ttggatatag tagatatcgt cgatgtttac tttatagact gttttctgcg tctgaataat
     6241 catatatttc attggattct cctcctaaga aaagaataac agaaaaggtc tagcccaagc
     6301 acacccaatc ctaaacagtc tttgaaaact cctaaaagga ttattttcta caacatcatg
     6361 atgagcttac aactatttta tcataaaatt cactcagcgc aattcaagac atttcaatga
     6421 caattaaaga tttgaataaa aaaaaagaat taaaagtgat aaactaacag tatcaaaaca
     6481 cagttgccag aagtaagact ggcacccaga ttaaaggagg cattcccatg acagatacag
     6541 accccatcaa aagagctcat actttgatta ctgacttaaa caaagcctac caagcatgca
     6601 aacaggcaag cgctgacgac gtccgctttc aggagcaatt aaactctatt cttggttttc
     6661 tagccaaggc tgaaacagtg gataatcgat tcttgattga actagaaaaa ttttaccaga
     6721 cttccagtct tctcatggga ctcagcgctc ttgatccaga tgctccaact cgcgccgctt
     6781 ggcgggccta tgaccgcttc cactttgacc aagtcaagac caagttaata ctcaatgaaa
     6841 atcaaagagc aaactaggaa gctagccgca agctgtactt gagtacggta agacgacgct
     6901 gacgtggttt gaagagattt tcgaagagta taagtctcta cggaccaacc attatcctgt
     6961 agtaacaaaa aagaagttga gacagactga actcaacttc ttttttagtg tcgtatcagc
     7021 aatgttagtc ctgcatctga cgttttacct gataaggcaa atacaagact agtaaaacca
     7081 aaccagctcc tagtaaggct agaagggcta gtttttcttg gaaggtaatc aacccaacaa
     7141 ctaattccac aagtaaaaca aaactggtca atcctcgaac tacctcctgt aagccttttt
     7201 ccttttgccc cttgtccagc ggaaagagtt gggtcaaata ctggtagtca aaggcatgat
     7261 agagggccag caactggaag agcaagaggt agttaaagag aactaccact gctgtcgcaa
     7321 tccaagcttg ctcgataaaa acctgcgcca gtacggaaag taagagaaga cgaagactga
     7381 gagcaaagag gtcgccattt cgcagataag aacgcagata gagattttgc caaatcttcc
     7441 caggcacctt ctgaacagcc tttaagataa agtccagata ggcacgacgc ttaacgctgt
     7501 ttgaaattcc cttgacctgc gtaaagaggg caaagaaacg aagcaagact tgcttacgct
     7561 tgctttcttg ggaaatgaca tagtcccagt ccagcccagt ttcagtgaaa aatttgctgg
     7621 ccttttgacg aaagtggaaa tattttccta cccccaataa aagcacatag agcagaaaaa
     7681 ctggcaagcc ataacccatt gctaaaaata aaggcgcaaa taacagcaag aaaagggtct
     7741 gtacaaagag ccaaaagact agggaaatgc cagtttgacg cttgagatgg agcttgattt
     7801 cctcttctcc aactaagaga aagagcttgt ctggagcctc catataggtg gcaattcctc
     7861 cccaaagtaa aagtaaaaca gacgtaattc ctacaaacaa aaggataggc caatgatttt
     7921 caggaaaatg ttgtaagagt tgactgtact ggtaggctag aaagcccaac aggacaagca
     7981 ggaacaagac aaagtggtca ttgagcacat agcgcagata accaagacac tccttacgaa
     8041 aggcctgctt tctctttaaa aacaagtctt tcatagatcc tcctctttgg tcagagccaa
     8101 gtaaatatca ttcaaactag cctcaggcat atcaaaggct tcacgtagtt gcaggagatt
     8161 gcctttggca cgcacctctc ccttgtgaag aatgacaaag gcatcacaca tcttctccgc
     8221 cgaatccagc acgtgggtac tcatgagaat agacttgccc ttttgcttct ccacttccaa
     8281 aagctgaatc aaatcagaaa tagccagcgg atcaagacca aggaaaggct catccacgat
     8341 gaaaagactt ggatccacca caaaagcaca gataatcatg accttctgct tcatcccttt
     8401 tgaaaaatga acagggaacc agtctaattt ctgttccaaa cggaacattt ttaacaaggg
     8461 ctctactcgt tcgaaagcca ctttttgctc aataccgtaa gccatagcaa ccgtttcgat
     8521 atgctctctg agggtcaatt cctcatacag actaggcgtc tcaggaatgt agccaatctg
     8581 cttgcggtag ctagtcgcat ctccttgcag agtcaggcca ttgatattga tggagccact
     8641 ataaggtgcc aacagaccga taatctcatt gatcgtcgtt gatttcccag caccattgag
     8701 accaatcaaa ccgaccaact gcccactttc aacagtaaag gacacatctt tcaaaacagg
     8761 aacatgaaca tagccacctg tcaggttttt aatttctaac atattttctc caaatctggt
     8821 ataatgtagc tatattatat caaaattcag tacagtagag gtagatttta tgtcagattg
     8881 cattttttgt aaaatcatcg caggggaaat tcctgcttca aaagtatatg aagatgagca
     8941 ggtccttgcc tttcttgata tctctcaagt aacactagga cacaccttgg tcgtgccaaa
     9001 agaacactat cgcaatcttt tggagatgga tgctacgagc gccagccaac tctttgccca
     9061 agtaccaaaa gtagctcaaa aagtcatgaa agtcactaag gctgctggta tgaatatcat
     9121 ttccaactgt gaagaagtcg ctggtcaaac agtttttcat actcacgttc accttgtgcc
     9181 tcgctacagt gctgacgatg acctcaagat tgattttatc gcccacgaac cagactttga
     9241 caaacttgct caagtcgctg aaaccatcaa aaacgcttaa ggagttgcta tgaaattatc
     9301 caacctactg ctatttgcag gagctgcagc cggaagttat ctggttacaa aaaatcgcca
     9361 aaccatcaca gatgaagtct tgaataccac tgaccgcgtt caagctatca aggacgatgt
     9421 ggatattatc caaaacagcc tgcaaatcat taaccagcaa aaagaactta tcaaggaata
     9481 ccaagaagac ttgacttaca agtttaaggt cttggaaaag gatatccaga ctagactagc
     9541 tgtgataaaa gaaatgcagg gaactgaaga taagtaaaaa gagcccgacg gctctttttt
     9601 aaaacgtaaa caagttatag tgaattgaat ttagaatagc acatcatagt ttctaaagca
     9661 ttgttagaga ttactttaaa atcctcttat caatttgttc atattctatt tcaatctact
     9721 atatatatcc catcaactat gcatcataat ttaggtaact catactcaat aaaaatcaaa
     9781 aagcaaacta gaaagctagg cacagactgc tcaaaacacc gttttaaggt tgtggataga
     9841 actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt
     9901 aaccataccc atgacaagcc gacgctgacg tggtttgaag aaatttttga agagtatcat
     9961 tcaccatttc acaactaaat cgaagacttt ctgccgtaat gaaaacacct gaaacagctt
    10021 ggtttcagct gtccggaaac tttaagactt aggttcaaag tttaggtatg gaacttcgaa
    10081 ggaggtcgct accgtccgtc attacttagg aaagtcttaa aaaatctata aagtaaaaag
    10141 agcccgacag ctctttttgt ttatactcaa tgaaaatcaa aaagcaaact aggaaactag
    10201 ccacgggctg ctcaaaacac tgttttgagg ttgtagatac gactcacata tatacggcaa
    10261 ggcaacgctg acgtggtttg aagagatttt cgaagagtat tattctccat caaaggcatc
    10321 ttttatatgg tcaaagaagc cttttttctt tggatttact ttcaagtcac cagcagtcgc
    10381 gaattctttc aaggctactt tttggcggtc gttcaagcct gtcggtgtta cgacattaac
    10441 agtaacgtat tggtcaccaa ctgcaccgcc acgaaggctc ggtgccccct tactacgtag
    10501 gcggaatttc ttaccagtct gagttccctc tggaataacc aattcaacat caccgtgaac
    10561 agttggaata tctactgtat caccaagagc cgcttggaca aagttgaggt tgagattgta
    10621 gaagatagtc gttccttcac gttcaaactt gtcgctagct tctacagaaa ctactacata
    10681 caagtcacca taaggtccac cgttaaagcc tgcttcacct tgaccagcga ggcgaatttg
    10741 ttgacctgtt tccacaccag cagggatttt cacatgtacg ctatgagctt gtttctcatg
    10801 acctgttcca tgacaggttg tacatggata tttgatttct tttcctcgac cgtgacagac
    10861 atcacaggtt acttggcgac gcatcatacc aagaggagtc tgcgtatcga cgttaatgac
    10921 accagcgcca tgacagcgtc cacaagtgac tggacttgtc cctggcttag caccagagcc
    10981 attacatgta cgacagccag cttcacgatg atacttaact tccttctcag ttccgaagat
    11041 agcttcttca aaggtcaaat tgacacgata ctggagatca tctccttggc gaggagcgtt
    11101 tggattgcgc gaagaaccgc ctccgccgaa gaaacttgag aaaatatcct caaaaccacc
    11161 gaagccacct gccccattga aaccaccgaa accaccagct ccaccaaaac caccattggc
    11221 gcctgcagca ccatactggt cataggcagc acgtttttgg tcgtcactca aagtctcata
    11281 ggcttcttga acttccttgt acttgtcctc agcaccaggc tccttgttga tatctgggtg
    11341 atattttttg gaaagcttac gataagcctt tttgatttcg tctgccgaag cgtttttgga
    11401 tacccccaga cgatcataaa attcagtatt gttcatacaa gataccaaga ccgtaaaatt
    11461 cgactgaaaa ataggaaatc tgacgctgga gcgacgctcc tagacagatt tctctttttt
    11521 ccgagaattt aggtcgggtt caattccttt cttttatatt gatgagataa tactccagcc
    11581 actcggccct atcccttttt accgaaaaac agaggctggg ttgcaacctc tgtggttaga
    11641 ttattcattt gaaataaaaa tggttgtatt atctctagta gtaatcttca aagacctttt
    11701 agctaaatca aactcaaatt tattatagtg tgggtcttgt gttttatata ggtgtaactc
    11761 ctgacatata tgatccgaaa agtaaatcat aacatcttta aacacagaag tgtggtcata
    11821 tttactctta ccaacagcta cttctgtaaa ttctttataa atgacatttc catttctttc
    11881 cacagtcacc agcatttctg ttggattata atccaaatta aataattatt caaaaaaact
    11941 ttatcttttc atgataatct gcaatgtcag aaagattatt tttattaaca ctcataacac
    12001 tagcccctta tttttcagta aactctccgt ctacgacgtc atcgcctgcg tttcctgttg
    12061 cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc tgcggcttgt tcgtagagtt
    12121 tcacagcaag gccttgagct ttttcgttca acgcttcaag tttcgctttc atgtcgtcca
    12181 agttgttgtc ttcttgagct ttcttaaggt catcaagggc agcttgggca gcgtcacgtt
    12241 ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt ttcagtcgca aagattgctt
    12301 ggtctacttc attacgaagg tctacttctt ctttacgttt cttatcggct tcagcgtttg
    12361 cttctgcatc tttcatcatg cggtcgattt cttcgtcagt caaacctgag ttcgattgga
    12421 tgacaatagt ttgttctttt tgagttccaa ggtctttggc cttaacagac acgataccgt
    12481 tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc acgaggtgca gctgggatat
    12541 cagtcaattg gaagcgtcca agagtcttgt tatctgctgc cattgggcgt tcaccttgaa
    12601 gaacgtggat atcaacggct ggttggttgt ctgctgctgt tgagaagact tgtgatttag
    12661 atgttgggat tgtagtgttg cgatcgataa gttttgtaaa tactccaccc attgtttcga
    12721 taccaagtga caatggcgtt acatcaagaa ggacaacgtc cttgacatca ccagtaatca
    12781 caccaccttg gatagccgca cccatagcaa ctacttcatc agggtttact gatttgtttg
    12841 gttctttacc agtttcagct ttaacagctt caacaacggc agggatacga gttgaaccac
    12901 caacaaggat aacttcgtcg atttctgaca agctcaaacc tgcatctgaa agggcttgac
    12961 gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa atcatcaaat ttcgcacgag
    13021 tcaaagtcat ttccaagtga agaggtccag cctcacctgc agtgataaat ggcaagctga
    13081 tttgtgttga agttacacca gaaaggtctt tcttcgcttt ttcagccgca tctttcaaac
    13141 gttgcattgc catcttgtca gtagacaagt cgataccgtt ttctttcttg aattctgcta
    13201 ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc aagtttgttg tcccctgcag
    13261 ttgacaatac gtcgaagaca ccgtcaccca attcaaggat agagacgtcg aatgtaccac
    13321 caccaaggtc aaataccaag attttttctt ctttgtcagt cttgtccaaa ccataagcaa
    13381 gagctgctgc agttggttcg ttaacaatac gttctacttc aagaccagca attttaccag
    13441 catcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc cggaactgtg ataacagctt
    13501 tggttacttt ctcaccaagg tagtcttcag cgtagccttt caagtattga aggatcatag
    13561 ctgagatttc ttgtggagtg tattcttttc catttgcaga aactttttca gaagttccca
    13621 tcttagattt gatagagata actgtatctg ggtttgtgac tgcttgacgt tttgcagcat
    13681 caccaacgat gatttctccg tttttgaatg agactacaga tggagttgtg cggtttcctt
    13741 ctgggtttgc gatgattttg ctttcagttc cttcaagaac tgcaactgct gagtttgttg
    13801 tacctaagtc aataccgata attttagaca tgtgtttttc tccttgttag ttaattttct
    13861 atttttcttt ttgatactct tcttaagtgg cgacgccgtc agagcttgac ttcgtcaatc
    13921 tctttgacta aactttgagc ctaaggtctc aaaatttgcg caaatagcac cacggcgaag
    13981 agtatcgtct ttggttcgct tcgctcacta ttacaaagcc aaacatattt tatctttctt
    14041 catagtttat tgtcgtttcg gacaagtttt ctattatgta aattgcgaca cgaggagtcg
    14101 aaatcgattt tatttcgacg acgagttagt aaggaagcta ggcaaacgtc atagcgattg
    14161 ccgttttctg acgagttgct ttagctaccg tcagaattgc cgaatcgaac acgccctaag
    14221 ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac acttcgtcaa tctcctattt
    14281 ttactgcgag ctttttacga gctttgtatc ttagttatac accactacca ttgctgggcg
    14341 taggatgcgg tcatggagtt tgtagccttt ttgaaagact tgggcgatgg tatctactgg
    14401 gtgttcatcg tctgctggga gagtttggat ggccatatgg tagttatggt caaattcgcc
    14461 atctgctgcg atttcttcaa ttccttcttc tttcaaagcg tgaatcaagc tttcttgcac
    14521 catcgccaag cccttcttca catcatctgt caaaccttca actgcaagtg cacgctcaag
    14581 gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg ctacgataac gttgcaagtt
    14641 ttgacgttct tcattggcac ggcgttggat attttgcatt tctgcatgag cgcgaagata
    14701 tttgttttcg aactcatctg cacgttcatt tgccaagtcc aactcagact tttcaggagt
    14761 tgtttcttca gctgtttcca caacttcctc ttcttgaact tcttctactt cttcattttt
    14821 tatatcttgg gccatgttcg cctcctttaa tgatttcaat cttaatgtac ttcgtaatga
    14881 ttactgctga ggtagcggta aaaatctgtc aacttcatgg tcaaaacacg gttgaccaca
    14941 ttgacttgat tgattagctg ttggtaatcc agattaactg gaccgataat ggctagaatt
    15001 ccaactcctc gataaggaat gaggaactta ctactaatca ccgctaggtc agctaaacag
    15061 gactcttgac cgtctgcaac acgaacattt tgcatctgat cctcacgcaa cccctcacga
    15121 atctccaagg ccaccttttg cggttggtca aagaactgat aggcttctag attggcaaaa
    15181 ttcaagagat tgaccttgcc cgccatcaca atgttttcgt tgaacatttc cttaaagatg
    15241 tgttcaaaga gatcgatgac attatccgtt gttgtaaagt aacgctggat aatctgcgga
    15301 atctccgtcc gaatcttgta gtgaatatct aaaacggtgt gaccgaggaa acgttcctga
    15361 atgatgctct tcagtttcag caaatcctcc tgcaagaagt tccttggaat cagaaactga
    15421 ctagtaaccg ttcgcgactc gtctagggta aataccgcca aggctgtatg ttgccccaaa
    15481 acaacgatat caaaggctgt caaacgttgc ctgctcggct caacatccag tgccactacc
    15541 gtacagccac tcaggtctgt tagcaagtta gcagcctctt gcagaatatc ctccaatttg
    15601 aagaattcct gatcaaaggc tttgacaatc tcatatacct cattttcagc cagccggtga
    15661 aaatccagtg agtgtttcac atagtactga aaaccagcaa cacttggcat ccgaccgctt
    15721 gaagtatgag ccttctcaag caacccttgt ttttctagtt ccgccatgtc attacgaatg
    15781 gttgcactgc tagagttaat agactcttgc aaggcttttg atccgacagg ttcgtgcgtt
    15841 ttggtaaaga tgtcaataat cagatttaaa atatcctgct gacgctctgt aaccatctca
    15901 tcactcctct ctgtctgatc aattagcact caatgcatcc aagtgctaac ttatgattct
    15961 attatacacc cttaaaagag aatgtcaaga caaaaactca aaaaattagc actcttttat
    16021 caagagtgct aaaaatcaat ctgaagacct agaaccttgc tattcatcta ctcgatattt
    16081 cctttttagt ctgaaataac catgaattag ataagaaatc agaaaagcat ataaaacaaa
    16141 aataagaaag aaagacatag aaagatcctc tctaaacaaa ctcgtacaaa caacaagacc
    16201 acctaagaaa gtagttgtac aggaacgaag tctagatcgc ataacttccc atttgagccc
    16261 cttactcata tagacttgat cctctggaag taaatcagaa gacgatttac gaagaatcga
    16321 acaagaacct gctcctatca attcccaacc tctatctcta aaatcttgca gttcatgctt
    16381 atatttttta agaaatctag aatcatagat acggtagatg acatcgtctg gttgacattg
    16441 gtcaaaatag aacaaaccaa aacgactcgt tctatacctc caacctttca aatgcatctc
    16501 atgtaaatat tcttcttact tgtccaaatc aacaatggtg aaaatccgaa attctactct
    16561 gctattcatt gtcttacccc aaaattagaa aacatgcctg gcgttattta ttagataatt
    16621 ctttccactt ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca
    16681 ataaaaccca atctattatg aaaatcaaaa acactttcca actgaaagaa ctacctccag
    16741 tgacaaactt tgagaaaaac ggtagtagag ctaaaaagag aagtaaaata ggaagcatcc
    16801 gcattgttaa aatccgtttg gcataaaaaa atctttattt aaactaaaat attatatcaa
    16861 aatttacgcc agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat
    16921 gtgattattt atttttgaaa aatagctcac cagcccgact gaaagtgctt atagaatgat
    16981 aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt atgcggagat aatctgacgc
    17041 gatgcgaaag tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt
    17101 gatataatag aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga
    17161 atgcggaggg ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga
    17221 tattaaagca aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca
    17281 tatcgcttac gaagaatact tcactgatgg tcgaattgag gttagaggag ataaggctcg
    17341 tcgtaaagaa ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc
    17401 aattgttgag gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga
    17461 atatggagag attttagatg ttccatttgt ttattcttcg aatggtgatg gctttattga
    17521 acacgaccgt atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga
    17581 agaattattt tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat
    17641 ctcaactcca tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat
    17701 agctatcaac cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat
    17761 ggcaacagga acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc
    17821 tggtttggct aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat
    17881 ggctgaagac tttaggccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac
    17941 tgctcctgaa aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg
    18001 tgaagatgga actgaaacac attatcaaaa atttgacaaa gacttctttg atttaatcgt
    18061 aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga
    18121 ttatttcagt tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc
    18181 ttccaatacg gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga
    18241 ggatggtttt ttggctccat atcgtgttat gagagttaat ttagatgtag atgtggatgg
    18301 ttatcgtcca gaaactggaa aagttgatgc taacggacaa ttaatagaag ataggtacta
    18361 cggcaggaaa gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa
    18421 gtttgtttct gattatatga agcaaaacaa tgcacgattt gataaaacaa ttgttttttg
    18481 tgttgatatt gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt
    18541 agtccaagaa gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc
    18601 tcaactggat aactttatgg atgtcaattc taattttccc gctattgtaa caacgtctaa
    18661 attattaacg acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat
    18721 ccaatccatg actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa
    18781 ggggaaagaa ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc
    18841 tgattttgat ggtgatccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc
    18901 tacgcccggt ttcgtaagtg aggaaggtga cccagtagaa aaatatatcg ttacagacaa
    18961 gcaggttacc attcttaatt ctactgttca agtattggat gaaaacggga aactgattac
    19021 cgaaagcctg accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga
    19081 ttttatcaca gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa
    19141 aaaaggagtt tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga
    19201 tgattttgat ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg
    19261 tatcaataag ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt
    19321 tttggaaatt ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga
    19381 aacattaaaa cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta
    19441 ttttggagat aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac
    19501 agtagcttaa tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat
    19561 cactcgaaac gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt
    19621 attattctta aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta
    19681 tgagtcaatt atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga
    19741 acgggtattg acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt
    19801 gaaagagctt gaaataactt caaatatgcc tattcgaaaa acgattgtta aatcagcttt
    19861 taaagatgcg aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgttat
    19921 tgatgaagtt gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa
    19981 aattcttaaa gatattcaaa atgctgggaa ctcaggagaa ttttatacac cacgtgcagc
    20041 gactgatttt attgccgaag ttcttgaccc aaaacttgga gaatcaatgg cagaccttgc
    20101 ttgcggaaca ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac
    20161 tagtgaagat accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc
    20221 tcatctttta gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca
    20281 tggaaatact ttagagaaaa atgttcgtga atatacggat gatgaaaaat ttgacattat
    20341 tatgatgaat ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc
    20401 agaattacgg agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa
    20461 agaaaatggt cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa
    20521 aactcgcttg aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc
    20581 tcatagtgtc tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac
    20641 aaagaaaaca gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt
    20701 ctcgaaaact aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa
    20761 tcgtgaagag attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt
    20821 ggctgagttg aattataatt tagaccagtg tggttttcca aaagaggaag aggaaatctt
    20881 aaatcccttt gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat
    20941 tgataatgta ttagctgata ttttgcagtt gttggaggac aaataatgac accagaacaa
    21001 cttaaggcaa gtattctcca aagagcgatg gaagggaaat tagtgccgca aaatcccaat
    21061 gacgaacctg caagtgaatt attaaagaga attaaagctg aaaaagaaaa acttatcagt
    21121 gaaggaaaaa tcaaacgaga taaaaaggaa actgagatat ttcgtggtga tgatg
//
LOCUS       DAVKUR010000037        20530 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKUR010000037 DAVKUR010000000
VERSION     DAVKUR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.037"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            44..1819
                     /locus_tag="VW749_001480"
     CDS             44..1819
                     /locus_tag="VW749_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEV0175502.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKERYKDFPIYTLYMKLS"
     gene            complement(2030..2836)
                     /gene="yidA"
                     /locus_tag="VW749_001481"
     CDS             complement(2030..2836)
                     /gene="yidA"
                     /locus_tag="VW749_001481"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0175503.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(2849..4153)
                     /locus_tag="VW749_001482"
     CDS             complement(2849..4153)
                     /locus_tag="VW749_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0175504.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            4225..4602
                     /locus_tag="VW749_001483"
     CDS             4225..4602
                     /locus_tag="VW749_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0175505.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            4692..5024
                     /locus_tag="VW749_001484"
     CDS             4692..5024
                     /locus_tag="VW749_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0175506.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            5036..6607
                     /gene="ffh"
                     /locus_tag="VW749_001485"
     CDS             5036..6607
                     /gene="ffh"
                     /locus_tag="VW749_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0175507.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(6802..8085)
                     /locus_tag="VW749_001486"
     CDS             complement(6802..8085)
                     /locus_tag="VW749_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0175508.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTSGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(8339..9052)
                     /gene="rsmG"
                     /locus_tag="VW749_001487"
     CDS             complement(8339..9052)
                     /gene="rsmG"
                     /locus_tag="VW749_001487"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0175509.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            9146..9706
                     /locus_tag="VW749_001488"
     CDS             9146..9706
                     /locus_tag="VW749_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0175510.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            9708..10607
                     /gene="htpX"
                     /locus_tag="VW749_001489"
     CDS             9708..10607
                     /gene="htpX"
                     /locus_tag="VW749_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0175511.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10756..12315)
                     /locus_tag="VW749_001490"
     CDS             complement(10756..12315)
                     /locus_tag="VW749_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0175512.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(12554..12871)
                     /locus_tag="VW749_001491"
     CDS             complement(12554..12871)
                     /locus_tag="VW749_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0175513.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            13041..13583
                     /locus_tag="VW749_001492"
     CDS             13041..13583
                     /locus_tag="VW749_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0175514.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            13583..14212
                     /gene="nth"
                     /locus_tag="VW749_001493"
     CDS             13583..14212
                     /gene="nth"
                     /locus_tag="VW749_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0175515.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            14423..14944
                     /gene="pyrR"
                     /locus_tag="VW749_001494"
     CDS             14423..14944
                     /gene="pyrR"
                     /locus_tag="VW749_001494"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0175516.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            14963..15886
                     /locus_tag="VW749_001495"
     CDS             14963..15886
                     /locus_tag="VW749_001495"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0175517.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            15936..17015
                     /gene="carA"
                     /locus_tag="VW749_001496"
     CDS             15936..17015
                     /gene="carA"
                     /locus_tag="VW749_001496"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0175518.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            17328..20504
                     /gene="carB"
                     /locus_tag="VW749_001497"
     CDS             17328..20504
                     /gene="carB"
                     /locus_tag="VW749_001497"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0175519.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6145 a         3837 c         4508 g         6040 t
ORIGIN      
        1 tgctataata taaagtatat agagttattt tagaggtgca gatttggcca ataataggaa
       61 aactgagaca ttaggtgttt catatctttc aacatttata gataagcatg agttacttca
      121 atcttatttt gaaagtaatg ataaaactcc agtatgggat ggagaaattc atgttcttaa
      181 atcaccgagt gagaagaaag acgaaatatt aggtaaagta cctgttcaga ttaaaactac
      241 tagacagaaa aaagatgtgt taaaatcctt ctcattagat actagagatt tagaactata
      301 taaaccaaat ggtggagtag ttttatttgt agtttggttg aatgaggata atggtttaag
      361 agatatttac tataagtcat tacctcctct ttctataaag aatttgctca aaaagagtaa
      421 actaaaaaat aaatctacaa ataggaagaa actttccata gagattttta aactggatga
      481 gaaaaaaatg tatccaatgt tagtggattt cataaacaat agtcagaagc agtatagttt
      541 cataaatgtc gaaggtattt cagttgagga cattcctgat gataaaactc taaagttcta
      601 cttctatggt caggaaaaag aagaaatttt taactatcag gaagaacatg atctctttat
      661 ttattattta gatcctataa ctggcataga aatacctctt gaaaacacaa taaagattgt
      721 agaaactgaa gaagaaacgg atttaattat aaaaataggc gattatgttt ttcaagacgt
      781 aaaaagacat cgttttcctg atgggagtgt acagcttcat tttggtgaaa gctttacaat
      841 gtcttttgac ataaagaaga aacaattcaa atttaactat actaggccgg atttgctgtc
      901 aaaagctata aagtgtactc aggtatttca agagctagga aaaatcggat attttaccct
      961 taatggtaat aaaatagagt tagatgaacg gtcaataaag gatatttctt cacttgattt
     1021 agaggctgat ataaagggat tgttaaaaat ttctaacttt atgaaaaaaa tgggtataca
     1081 aaaagatgtt gatttatctt gctttgataa acaatctcaa agaaatctaa atattcttta
     1141 ttcaggtctt gtcttaaaaa agaaagttgc tttaaattat aatgaatcga aattacttca
     1201 cctaaatatt gctaacatcc acattataac tttatatagt tttttgtcag ataaaaatgg
     1261 aactatgata gacattttta ctgaaactcc ttggtgccgg gaaggagaaa ctgaagatga
     1321 agattattta gacatttcaa tttttgaagt atttgaacca aacgattggc taaaaattga
     1381 taattgtaaa attgattcag ttattgcctc gtatcaaaga ttggtagata ataagctgaa
     1441 atatgaaggc gctgaccgta ctattttaaa aatagttatc gctgcagaca tggcagaaga
     1501 taagactaaa agagagttgt tacttaattg ggcgcaatgt ctttctgact ggaacttaaa
     1561 atactcaaaa aattgtgaga tggctataat aaatgacctt caaataaaat ctagagttcg
     1621 taaattaaac agcaaagaaa cagagacact aactaatatt ttagtaaata gtaatgataa
     1681 ctatgaactt tgtttcggtt catcagtgct attaaaatcg aaaccacaag ctgatttgtt
     1741 ttggaataaa ctggataatg agacaaaaga aagatataag gactttccta tttatacttt
     1801 gtatatgaaa ttatcgtaaa attaaaagag attataaaga gataacatat agaaatagag
     1861 agtgatttat tacaattcag taccacaaat taagaaagca atgcctattt tttgtactct
     1921 caagatttaa gtaactgtac aactgcaatt aaatttatta atttactctc attgtgatat
     1981 attcatacaa aaaccgctca gctgagcggt tttagtctat tctttccttt tacagtaccc
     2041 atgttcggat ggcgtgggca acgccggatt cgtcatttgt tttagtgatg tatttggcga
     2101 tttttttgat ttctggattt ccattttcca tgacaacggg gtttccaacg acttccagca
     2161 tggcacggtc attttcttcg tcaccgattg ccatggtttc atctttggtc aatccgagtt
     2221 tttcagccaa gtgagtaatg gctgaaccct tgtctacatt ctttgtaagg agttcgaggt
     2281 agaaaggagc agatttgttg atggagtagc gctcgtaaaa ttctgctgga attttttcaa
     2341 tcgtagcatc gaggatttct ggttcatcga tgaacataca tttgacaatt tccttgtcag
     2401 ccatttcttc aggtgtacgg tagaagatag gcatgctgac gagggttgat tcgtgcacag
     2461 tgtattttcc gatattgcga ttggcagtat agataccgtc cttggtaatg gcgtgcatgt
     2521 ggacaccgag cttgcggctg agaaattcca tatctagata atcctcataa gtcaaggatt
     2581 cgctgataat ctcatgtcct gtagcagttt cttggacaag ggcaccgttg aaggttacca
     2641 catagtcccc ctcgtctctc aactgcaagt cgtctagaag tttggcaacg cctgcgatag
     2701 ggcggccagt tgcaatcacg actttgacac cagcttcttt ggcatcttgg atggcagaaa
     2761 agacttcagg agtgatttcc ttttggctgt tgactagggt tccgtcaata tcgacggcga
     2821 ttagtttaat actcataaat ttcctctttt agtttttatt tggggtaaaa tgatcgttct
     2881 caatcaagtg taaaaattgc tgggtgatgc ttgcgaagat gctgttttgg tctaacattt
     2941 ctttcgggaa ataaaagcga ttatctccgt ggcgacttcc agcaagggat tggacgatag
     3001 gggacaggct agagagttct gccagttctc catttttttg taaaatctca atctgtgtcc
     3061 ttggattttc agattcggga cggtaaatat cataagggag gtcaaagttc ttatgaatgg
     3121 cagtatagta gtcgggatca aagccgatgt cctcaaccaa ttttctcatg ctagcgagtt
     3181 ggtcttggtc ttcttgtgaa aaggtaatgg atttaaagac cttgcggttg acaaagcgat
     3241 gcgataaatc tgcaagaatc ttgtcaggac tggtcatcca gagttggaag taggtattca
     3301 tcacaccatc atccagagcc agatagtcag tcaaggtcac atttttttcg aagaaaggca
     3361 ggaggtgtgg agaagttcgg gcaaagaaat ccttgtcctc aggatagagt tccttggcgc
     3421 gtttgagaag attctgtagg agaacttcca tggcgcgtgt tgcggggtgg aaataaacct
     3481 gcatgtacat ctggtagcga ctgaggacgt agtcttcgat ggcgtgcatg ccattgcgct
     3541 gaaaggcgat accattttcg ataggacgaa tgactcggag gattcgagtc aggtcaaatt
     3601 ccccatagga tgctcctgta aaataggagt cgcgcaagag atagtccatg cgatctgcgt
     3661 caatctgact agaaatgagc tgcacgacct gcttgttagg ataggtatgg tctatgacac
     3721 tggcaacttt ctctggaaaa tcgggcgcta cttgtagcag gacttggtga atctctgtct
     3781 caggattttg aataatctcc tgagtaatgg cttcatggtc tgtatcaaag agattttcaa
     3841 aagtatggga gtaggcacca tgcccaaggt cgtgtaggag agcagcggtc atggtcaaga
     3901 gagactcggc aggattccat tcctcaggat atttttcttc gaaaatctct gtgatgcgtc
     3961 gtgcaatttc atagactcct agacagtgag agaagcgact gtgttctcca ccgtggaagg
     4021 tataactgga agttcccagt tgtttgatcc ggcgcaaacg ctgaaattct tttgtattaa
     4081 tcaagtcata gatgatttga ttattgacat ggatgtagtt gtgaacaggg tcacggaata
     4141 ctttttcgtt catatgacca ttatagcaaa atcctgctct ttttggtaaa atagtaggac
     4201 aagagacaag aaagagggcc tgatgtgaag attcggatgc gaaatacaat tcagtttgat
     4261 gagcagttgg aagtgattga ccagctttat gatgtggaag tgcatgaaaa aggagattat
     4321 agctacctgc ttttctataa tgaggaaaag gaaaaagtag tgattaaatt tcatggtcaa
     4381 gaacttatga tgagccgatt ttccaatccc aagaccatta tgcgcttttt aaaggatagt
     4441 gatagtttgg cctatattcc tacccctatg ggcatgcagg aatttatcat tcaaacgagc
     4501 cgttatcaag tagatgggca aaagattgag ctagcttatc aactacaaaa tcaagagggg
     4561 catccctttg ccagctatca attggaaatt acttggggct aggatctcgt ttttctcaaa
     4621 tctactttct atcttcaagg attggctccc tagtgtggta gattaggcta ttttttggta
     4681 taataaaagt tatggaaatc gaaaaaacca atcgtatgaa tgcgctcttt gaattttatg
     4741 cggcgctttt gacagataag caaatgaatt atatcgagct ttactacgct gatgattaca
     4801 gtcttgctga gatagctgag gagtttggtg ttagtcgtca ggctgtctat gacaatatca
     4861 agcgaacaga aaagattctg gaagattatg agatgaaatt gcacatgtac tcggactaca
     4921 ttgtccgtag tcagattttt gaccaaatct tggagcgcta tcccaaggat gattttctgc
     4981 aggagcagat agaaatttta acaagcattg ataatagaga ataagaggaa gaaaaatggc
     5041 atttgaaagt ttaacagaac gtttgcagaa cgtctttaaa aatctacgta aaaaaggaaa
     5101 aatctctgaa tctgatgtcc aagaggcaac caaagaaatt cgcttggcct tgctcgaggc
     5161 cgacgttgcc ttgcctgttg taaaggactt tatcaagaaa gttcgtgagc gtgcagtcgg
     5221 gcatgaggtc attgatacac ttaatcctgc gcaacagatt attaaaatcg ttgatgagga
     5281 actgacagcc gttttaggtt ctgatacggc agaaattatc aagtcaccta agattccaac
     5341 catcatcatg atggttggtt tacaaggggc tggtaaaaca acctttgctg gtaaattggc
     5401 caacaaactc aagaaagaag aaaatgctcg tcctttgatg attgcggcgg atatttatcg
     5461 tccagctgcc attgaccagc ttaagacctt gggacaacag attgatgtgc ctgtctttgc
     5521 acttggaaca gaagtaccag ctgttgagat tgtacgtcaa ggtttggagc aagcccaaac
     5581 taatcataac gactatgtct tgattgatac tgcgggtcgt ttgcagattg atgagctcct
     5641 catgaatgag cttcgtgatg tgaaagcatt ggctcaacca aatgaaatct tgcttgtcgt
     5701 tgatgctatg attggtcagg aagcagccaa tgttgcgcgt gagtttaatg ctcagttgga
     5761 agtgactggg gtcatcctta ccaagattga tggcgatact cgtggtggtg ctgctctgtc
     5821 tgttcgtcac attactggaa aaccaatcaa gttcactggt acaggtgaaa agattacgga
     5881 cattgaaacc ttccacccag accgcatgtc tagccgtatc cttggtatgg gggatatgct
     5941 cactttgatt gagaaagctt ctcaggaata cgatgaacaa aaagcccttg aaatggctga
     6001 gaagatgcgc gaaaacacct ttgattttaa tgatttcatc gatcaattag atcaggtgca
     6061 aaatatgggg ccgatggaag acttgctcaa gatgattcca ggtatggcca acaatccagc
     6121 ccttcaaaac atgaaggtgg atgaacgcca gattgctcgt aaacgtgcca ttgtgtcttc
     6181 gatgacacct gaagagcgtg aaaacccaga tttgttaaat ccaagccgtc gccgtcgtat
     6241 tgctgctggt tctggaaata cattcgtcga agtcaataaa ttcatcaagg actttaacca
     6301 ggctaaacag ctcatgcagg gtgttatgtc tggggatatg aataaaatga tgaagcaaat
     6361 ggggattaat ccaaataacc ttcctaaaaa tatgccaaat atgggaggaa tggatatgtc
     6421 tgcccttgaa ggaatgatgg gacaaggcgg tatgcctgac ttatcagctc tcggaggagc
     6481 aggaatgcca gatatgagcc agatgtttgg tggcggtttg aaaggtaaaa ttggtgaatt
     6541 tgccatgaaa cagtccatga aacgtatggc taacaaaatg aagaaagcga agaagaaacg
     6601 caagtaagac aagagattga tgcaaatctc atttgatgag aaaataaagt aaaaatttct
     6661 atgataaaac gtacagtatc aaggttttag aatatctgat attatacgtt ttttgatttt
     6721 aataattttg ttaagacact tttattatag tatacgaaaa atccactcag ctgtctgagt
     6781 ggattaggtg tatttagact cttagtcttt attttcgtat ggcaagatca agttcaagat
     6841 gattcctgtc atggctgaaa gggcagtacc tgaaagtgta actggaccaa gtttaaggat
     6901 agctcctcca agtccaagaa ccaacatagc acttgcgatg atgaggtttc gcatttgagc
     6961 gaaatcaaca cgttctttaa tcaagacttt caaaccattg ctggcgataa ccccatagag
     7021 aaggattgac ataccaccaa gtacagcgtt tggaatagtt gaaatcaagg cagtgaattt
     7081 accaaggaag ctgagggcaa tcgcgatgaa ggcagcgtta cggataactg agacagaagc
     7141 gatacgagtc ataccgataa cccctgtatt ttctccgtaa gttgtattgg ctggtccacc
     7201 aaggaaggca gaaacagaag ttgcgatacc gtcaccaata agagtacggt gaagacctgg
     7261 ttcttttaag aattgacggc cacagatttg acccaaaaca gtatggtctc cgatatgttc
     7321 agaaattgtt acgatagcga ttggcaagat agcgatggct tctggaccaa agtaaagatt
     7381 gtactcttta aaggcaccac ttgtgctaaa tggcaagtag aaaccaggaa tttcaaacca
     7441 gttagcttct aggacaggcg taaagtcaac caaaccaaga gttagtgcga agaggtaacc
     7501 accgataatg gcaaagagga atggaatgat tcgtaggaag ccttttcctt ttgtattgat
     7561 aaaggcagca attaggaaag taacaacggc taccagagca tttttccaat ttccgtctgc
     7621 tacaagacct gcattggtaa cagctgaacc tgcaagtcca agaccgataa cgatgatcat
     7681 aggaccgata atgattggtg gcaagagttt atcaatccat tttgttccta caaatcggat
     7741 gctggtagca acaaggacat agaccaaacc agtcaagata acccctgttt gagcagcaga
     7801 tacatccccc cccatttctt tcatagccag tgacatagct gtgataaagg cgaatgaaga
     7861 acctagataa actggaactt taaaaccagt agcaagcatg tagatgagtg ttccaacacc
     7921 tgaagcaaaa agggcaacag atacaggcat tcccaaaatc aatggtacca agatggtcgc
     7981 accaaacatg gcgaaaacgt gttggaaact aaggagaatt ccttttccag ccgaaggacg
     8041 ttggtcaacg tctagtaaca aatcaacagt tgattcttgt ttcatataaa cctcactttt
     8101 gggcatcaaa aaagagccca ttattttaca gcaataggcc ctcagagtaa gacttcttta
     8161 aaatttagat tttaaagagt tttaaatatt tctgcgtctt cgtcacctca cgggatgaca
     8221 ttaaaaacct ttgcttagga tagtatagca gaaaaaaatg attttgtaaa tcattttttc
     8281 ccgagcctag aaataaaaga gcgaggctga ttttgtaaac atttgtttac taaaaaattt
     8341 aaagtgggcg tttatttggc ataccagcct tacgtggata tttatttggt gtttcttttt
     8401 tcttttctac cactgtgata tagcgcggat ctctattcgg tagggcgtag ctgagattgt
     8461 cttcgacctt actaaaaagg agattgaggg cattcttagc ttctaataat tcctcaggcg
     8521 cattgctggc cttgagtgcc aatagttttc caccaacctt aaggtaggga atggtcaatt
     8581 cagataggac ctgcatacgg gcaaccgcac gagctgttac aaaatcatat tgagcacgga
     8641 agttcttgtc ttgggcaaaa tcttcggcac gtccgtggta gaaatgaact ccgttcaaat
     8701 ccagttcttg agccaagagt tgtaggaagt tgatgcgctt attgagtgaa tcaataatgg
     8761 tcacatctaa ctccggatag agaattttca ttggtagact aggaaatcct gccccagccc
     8821 cgatatcaag aagtttgata gtttcattgg gaatcaaacc ttgaagaatg ggtgcaatcg
     8881 aatcgtaaaa atgtttgaga taaacttctt ccttgtccgt aatcgccgtc aaattaatct
     8941 tctcattcca ctcgaccaag agctcaaaat aacgttcaaa ttgttctttt tgctggtccg
     9001 aaagtggaag attctgctcg gcaagcaagt tgtaaaatgt ttttggtttc atagttattt
     9061 ccttctttag tatcatctta ttttaccaca atcatagaaa atttgatata ctggtactaa
     9121 tctaaaagca gaaaggactt atattatgac ttggattatt cttggagtta tcgctcttat
     9181 tgttattttt gtgattgtta gctataacgg tttggttaaa aatcgtatgc aaaccaagga
     9241 ggcttggagt cagattgatg ttcagttgaa acgtcgaaat gacctcttgc cgaacttgat
     9301 tgagactgta aaaggttatg ccaaatatga aggttctacc cttgaaaagg tggcagaact
     9361 acgtaaccaa gtggcggcag cgacttcacc agcagaagct atgaaagcca gtgatgccct
     9421 cactcgtcag gtttcaggta tttttgcagt tgcagaaagc tatccagatt tgaaagctag
     9481 tgctaacttt gttaaattgc aagaggagtt gacaaacaca gaaaataaaa tttcttactc
     9541 tcgtcaactc tataacagtg ttgtcagcaa ctacaatgta aaattagaaa ctttcccgag
     9601 caatattatc gctggaatgt ttggatttaa agcggcagat ttccttcaaa cacctgaaga
     9661 ggaaaagtcg gttcctaaag ttgattttag cggtttaggt gactaagatg ttgtttgatc
     9721 aaattgcaag caataaacga aaaacctgga ttttgttgct ggtatttttc ctactcttag
     9781 ctcttgttgg ttatgcggtt ggttatctct ttataagatc tggacttggt ggtttggtta
     9841 tcgcactgat tatcggcttt atctacgctt tgtctatgat ttttcaatcg acagagattg
     9901 tcatgtccat gaatggagcg cgtgaggtgg atgagcaaac ggcaccagac ctctaccatg
     9961 tagtggaaga tatggctctg gtcgcccaga ttcctatgcc ccgtgttttc atcattgatg
    10021 atccagcctt aaatgccttt gcgacaggtt ctaatcctca aaatgcggct gttgctgcga
    10081 cttcaggtct actagctatc atgaatcgtg aagaactaga agctgttatg ggacatgaag
    10141 tcagtcatat tcgtaattat gatatccgta tttcgactat tgcagttgcc cttgctagtg
    10201 ctatcaccat gctttctagt atggcaggtc gtatgatgtg gtggggtgga gcaggtcgca
    10261 gacgaagtga tgatgaccga gatggaaatg gtcttgaaat cattatgcta gtggtttccc
    10321 tactagctat tgtactggca cctctcgctg caaccttggt tcagctcgct atttctcgtc
    10381 agagggaatt tctggcagat gcatctagtg tcgagctgac tcgcaatccc cagggaatga
    10441 ttaatgccct agataagttg gacaatagca aacctatgag tcgccacgtc gatgatgcta
    10501 gcagtgctct ttatatcaat gatcccaaga aaggtggggg gttccaaaaa ctcttttata
    10561 cccacccacc tatctcagaa cggattgaac gtttaaaaca gatgtaaaat gaaggctgga
    10621 aaaaagtctt taaaatctga aaaacgcata atatcaggtg tgaaaacttg atattatgcg
    10681 ttttactatg ggaagattta cttctttttc tcctaaaatt gtgtttttgc cccacctatc
    10741 tgctatgttg caaatttata aatcttctaa attaactagc ttcaaaccgt gttctgtcat
    10801 gcgatagatg atcgagcaga tttcttttaa gaaacgacgg tcatgcgaaa cagtgatgag
    10861 accgcctgga taggttgcaa agagttttct gatttggggt tgagaagtgg gagaaaagtt
    10921 tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc aggactaaat ccaaaagcag
    10981 gagttttccc tgttgtccgc cagataagga gcgaatttga tgctgcattt ctggataact
    11041 gaaattgaga ctggctaggt gagattggat tttctgaagt tcctcttttt ccccagtttt
    11101 gctgatataa gctattggtg ataaatccaa ttgcagtttt ttgtggtaat cttgtggcat
    11161 aaaaccaagg gaaatctctc ttttatcatt cagaagttgc tttaatttgg ctaacagagt
    11221 tgatttccca acaccatttg gcccgataat accgattttt tcttgcccac ggacagttag
    11281 ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa ttttcttttt ccagttggac
    11341 taagacttta gaagctggta atggttggat gtctgaaaag aaaagttgga tttgttcctc
    11401 ttcaagtggc ttttgagtca tggactgagc tgtcttttcg tagcgttttt cttgtgagag
    11461 gacagttttc atctttttag ccaataggcg accggcagta ctatctttgg tagctcgaag
    11521 cgcagtttct acattttgct taactctccg atgtttttcc atggttttat cgtaggctct
    11581 ttggttgtta gcagcttgct gactttgttt ggcaaaatta gcctttctct gctcactata
    11641 gctatcatag tctaaatgct ctactagcgt ttccgcttct ttacggtgtt tgaccagtcg
    11701 caagtgaaca atagtgtctg ctgtttcaga aagaaagtct tcatcatggg aaatgaaaat
    11761 aacggtttgc ctggtctttt gaatctggcc ttttagccaa tcaactgtct caaggtctag
    11821 gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt ttggctaact catggataag
    11881 ctgaattttc aaagcttctc cccctgatag attgccaatc ttttggtcac ttgcgaaacg
    11941 attgctatca aaatgcaatt cctccgccaa acgatagagg atactgtagt ctaaatcaat
    12001 agaatctaaa aagaagtagt cgtgtaaagt tttctttttc agctcctcgg gaagtttttg
    12061 aggaatgtag gccagtgact gatagtcaga ttggatgttt cccttgatag tgaaatcaga
    12121 caaagcttcc cccattaaaa ttttaagtaa ggttgatttg ccatttcctt cttcaccaat
    12181 aatagcaacc ttttccccgt cttggatggt catgcttagg tcagatacaa gatctcgtaa
    12241 atctttgttt tgtgtgatgg ttagatgatt gatttttatc atatgatttc cctttctaga
    12301 atgttcatag tgcataacaa aaagctctac tttacctagt agagcccaaa gtctatgtca
    12361 aaaaaactct attaacatgc cagaaaaaga gcataaaaga gcacacaaaa agagacaaaa
    12421 acaagatcta ctaaataaag gttctttatt tgatagactt agttgttcat gtctccctta
    12481 cctccgagta ttagtatctt tatattatac ctttaaggaa attttgtcaa cagaaaactg
    12541 gaaattctat gctctaaaat ccaaaaacag gtccatagag acttagtacg tgtttgacat
    12601 gctcgtaatg gaatttatca tagtttcgcc aagcagtgcg tgcttgatcg tttagtttta
    12661 ggctacccag tccaatcaga agactggtgg gttggtaaaa tttctcaaga tcaattaaga
    12721 tactgttgtt caacttttcc gtttttttga gctcttgcat agtagtgttt agcagctctt
    12781 gtagtcgaat atcatctgcc gtaccctgtt tacagttttg gtagctttta tttaacttgg
    12841 ataggagttg aatgagtttc ttgtcttcca tgtgagcatc ctccttgatc tgatgtactc
    12901 tttccctata gtatagcact aaaaaacaaa actgtcatag taaatatgtt aaaattctga
    12961 attttaatta caaagtttgg tgtgctgatt tgtagccttt tcatggtata atcaagagag
    13021 taaatcttta tggaggaagt atgaaattaa atattcaaga aattcgtaag cagtctgaag
    13081 gtttgaactt tgaacaaacg ttagatttag ttgatgacct gcgtgcacgt aatcaagaaa
    13141 ttttagatgt aaaagatatc cttgcagttg ggaaagtaca atatgaagac cgtatgtatt
    13201 tcttagatta tcaactatct tataccattg ttcttgcttc gagtcgcagt atggagccag
    13261 ttgagttagt tgaatcttat ccagtcacgg aagttttcat ggaaggcgca actaaccatc
    13321 taaatcaaga aattttagat gatgacttgg tcttgcccat cgaaaatgag gcgcttgacc
    13381 ttgctgagag tgtatcagac aatatcttgc taaacattcc tatcaaggtc ttgacggctg
    13441 aagaagaagc tggtcaagga tttgtctcag gaaatgactg gcaaatcatg acagaggaag
    13501 aataccaagc tcaacaagca gtaaagaaag aagaaaacag tccttttgct ggcttacaag
    13561 gactatttga cggagatgaa taatggtctt gtcaaaaaaa cgagcacgaa aggtgctaga
    13621 agaaatcatt gccctcttcc cagatgccaa gcctagtctt gattttacca atcattttga
    13681 actcctggtt gcggtcatgt tatcagccca gacgacagat gcagcggtaa ataaggccac
    13741 accaggtctc tttgttgcct ttccaacacc ccaagctatg tctgtagcga cagagagtga
    13801 gattgcttca catatttctc gcttgggatt gtatcggaat aaagctaaat tccttaaaaa
    13861 atgtgcccaa cagttactag acgattttga tggtcaagtc cctcagacac gtgaagaatt
    13921 ggagagtttg gcaggtgttg gtcgcaagac agccaatgtt gtcatgagtg taggatttgg
    13981 gattccagcc tttgcagttg atactcatgt ggagcgtatt tgcaaacacc acgatattgt
    14041 caaaaaatca gcgacgccac ttgaggtgga aaagcgggtc atggatatct tgccgcctga
    14101 gcagtggtta gctgcccatc aggccatgat ttattttgga agagccattt gccatccaaa
    14161 aaatccagag tgtgaccagt acccacaatt atatgatttt agcaatttgt aagatgctac
    14221 attgaaactt tttgcttgat tttaagcatg ctttgtgcta tagtaaatga taactaaata
    14281 ttcctttaaa cctgtcccgt gaggcaggca aggagcgcga taaagtagaa gggtgaagtc
    14341 tatactgtgt gcagtagggc tcgcttggct ataaatttca agtctccttg tttaaggaga
    14401 cttttctttt tggaggtttg tcatgaaaac aaaagaagtt gtagacgaat tgaccgtcaa
    14461 acgagcgatt acgcgtatta cttatgagat tatcgaacgc aacaaagatt tgaataagat
    14521 cgtcttggct ggtattaaaa ctcgtggtgt ctttattgcc caccgaatcc aagaacgttt
    14581 gaagcagtta gaaaatcttt cagttcctgt tgtggaattg gatactaaac ctttccgtga
    14641 tgatgttaaa agtggagaag atacttcttt ggtttctgtc gatgtgacag accgcgaagt
    14701 tatcttggtg gatgatgtgc tctatacagg tcgtaccatc cgtgctgcta ttgataatat
    14761 tgtcggtcat ggtcgtcctg cgcgtgtgag tttagcagtt ctagtcgatc gtggacatag
    14821 agaattgcca atccgtccag attacgttgg aaaaaatatc ccaaccagtc gttctgaaga
    14881 aatcatcgta gagatgacag aacttgatga ccaagacaga gttctgatta ctgaagaagc
    14941 ttagaaagtt aaaggagtag ccatgtcaga aaatcaacaa gcattgaacc atgtggtgtc
    15001 catggaagac ctcactgtcg atcaagtaat gaaattgatc aagcgaggaa ttgagtttaa
    15061 aaatggagcc cagcttccct atgaagacca tccgattgtt tccaatctct tctttgagga
    15121 ttctacacgg acacataagt cctttgaagt cgcagagatt aaacttggat tggaacgact
    15181 tgactttgat gtgaagacta gttcggttaa taagggtgag acactttatg acaccatttt
    15241 gactctgtct gctttaggag tggatgtctg tgtgattcgc catccagagg tcgactacta
    15301 tagagaattg attgctagtc caacgattac gacttccatc atcaatggtg gagatggttc
    15361 gggccaacac cctagccaga gcttgcttga tttgatgacc atttatgagg aatttggcca
    15421 ctttgagggt cttaaagttg ctattgcagg tgacttggac cactcacgcg ttgccaaatc
    15481 caatatgcag attttgaaac gcttgggatc tgaactcttt ttcgctggac ctgaggaatg
    15541 gagaagtcaa gagtttgcag actatggaca gtttgtaacc attgatgaaa tcattgatca
    15601 ggttgatgtc atgatgtttc tccgtgtgca acacgaacgc catgatagtg gagctgtatt
    15661 ttcaaaagaa gactaccatg cccaacatgg cttgactcaa gaacgttacg atcgtttgaa
    15721 agaaacagca atcctcatgc acccagctcc aatcaatcgt gatgtagaaa tagcagacca
    15781 cttggttgaa gcaccaaaat cacggattgt ccaacaaatg accaatggtg tctttgttcg
    15841 aatggcaatc ttagaatccg tactagcgag tagaaacgcc aactaaaaca caagacgtta
    15901 aaagacgcca gtgagcgtcc acgagaggtg aaaatatgac aaaaagaatt ctagtattag
    15961 aagatggcac agtttttgaa ggcaaggcct tcggagcaga tattgatgta acaggcgaaa
    16021 tcgtctttaa tacagggatg accggctacc aagaatccat tacagaccag tcttataatg
    16081 gacaaatctt gacctttact tatcctttgg taggaaatta tggtattaat cgtgatgatt
    16141 atgaatccat tattccaact tgtaagggag tcgttgtttt tgaagaagcg cgtagagcta
    16201 gcaactggcg caaccaaatg accttggatg aatttttgaa agccaagaaa attccaggga
    16261 tttcaggaat tgatacgcgt gctcttacca agattatccg taagcatggt actatgcgtg
    16321 caaccttgac ccatgttggg gacagtatgg accatgtgac ggaccagctc caagcaacag
    16381 ttttaccgac agacaatatc aaacaggttt ctactaaaac gtcttatcca gctccaggag
    16441 ttggtttgag cgtggtgcta gtggactttg gtctcaagca ctcaatccta cgtgaacttt
    16501 ctaaacgcaa ctgtaacgtg acagttgttc cttattcgac aacggctgaa gaaattctcc
    16561 atctcaatcc tgacggagtt atgttgtcaa atggtccagg taacccagaa gacgttccac
    16621 aagcactcga catgattcgc ggtgtacaag gaaaaattcc aatctttggt atttgtatgg
    16681 gacaccaact ctttgcaatg gcaaacgggg ctaagaccta taagatgaag tttggccacc
    16741 gtggattcaa ccatgcggta cgtgaaatcg caacaggacg agtagacttc accagccaga
    16801 accatggtta tgcagtcagc cgcgaggatt tgccagagca cttgattatt acccacgaag
    16861 aaatcaatga caagtcagtg gaaggtgtgc gccacagata ccaacctgct ttctctgttc
    16921 aataccaccc agatgcagct cctgggccac acgacgctag ctacctattt gacgagttta
    16981 tcgagatgat ggaagttttt aaacaatcaa actaagaacg agtaaaagct cgtcggagaa
    17041 tttatgtaac tgaacacgga cggaaagctc agaatgtaga gaaaccaact tggattgtca
    17101 atccttcctt gatttcctaa aattcaatcg ctttctattc gtcctttgta tcttatttaa
    17161 tgtcgccctg agaggcgacg aatagaaagg agaagggagc tccgtatttg ctgaactgaa
    17221 tacgggctac ggacggtgct aaaaagatag ttattcctag aactgacagt tcttcgtcat
    17281 aactcctatt ttagctttgt ccgcttgaca cccttaatat cttatatatg cctaaacgta
    17341 ctgatattca aaaaattatg gtgattggtt ctggtccgat tattattggt caggctgctg
    17401 agtttgacta cgctgggact caggcttgct tgtcgttgaa agaggaaggt tatgaggttg
    17461 ttttggttaa ctcaaatcct gcaaccatca tgacggacaa ggaaattgct gacaaggttt
    17521 acattgaacc gattacactt gagtttgtga cacgtattct tcgtaaggaa ggtccagatg
    17581 ccttgctacc aacactcggt ggtcagacag gtctcaacat ggccatggaa ttatctaaaa
    17641 atggtatcct agacgagctt ggcgttgaac ttctgggtac caaattatct gccattgacc
    17701 aagcggagga ccgtgatctc tttaaacaat tgatggaaga gcttgaacaa cccattccag
    17761 aatctgaaat tgttaacaca gtagaagaag cagttgcctt tgcagcgaca attggctacc
    17821 cagtcatcgt tcgtccagcc tttacccttg gtggtactgg tggtggtatg tgtgccaacg
    17881 agaaagaatt gcgtgaaatc actgaaaatg gtttgaaatt gtcacctgtt acccaatgtt
    17941 tgattgagcg ttcgattgcc ggtttcaagg aaattgaata cgaagtgatg cgtgactcag
    18001 ctgacaatgc cttggttgtt tgtaacatgg aaaactttga cccagttggg attcacacag
    18061 gggattccat tgtatttgcc cctgcgcaaa ccatgtcaga ctatgaaaac caaatgcttc
    18121 gtgatgcgag cttgagcatt attcgtgccc tcaagattga aggtggatgt aatgttcagc
    18181 tagctcttga tcctaacagc ttcaagtatt atgttatcga agtaaaccct cgtgtatcac
    18241 gttcgtcagc ccttgcttct aaagcgacag gatatccgat tgctaagttg gctgccaaga
    18301 ttgcagtagg tttgaccttg gatgaggtta taaacccagt tacaggttca acctatgcca
    18361 tgtttgaacc agcccttgac tacgtagttg ctaagattcc acgtttccca tttgacaagt
    18421 ttgaaaaggg tgaacgccgt ctcggtacac aaatgaaggc gactggagaa gtcatggcaa
    18481 tcggtcgtaa catcgaggaa tctcttctca aggcctgccg ctcccttgaa attggggtgc
    18541 accacaatga aatacctgaa cttgcagcag tttctgatga taccttgatt gaaaaggttg
    18601 tcaaagccca agatgaccgt ctcttctacg tatcagaagc cattcgtcgt ggctacacac
    18661 ctgaagaaat tgcagagctt acaaaaattg atatcttcta tcttgataaa ctcttgcata
    18721 tctttgaaat tgagcaagaa ttgggtgctc atccacaaga tctagaagtt ttgaaaacag
    18781 ccaaacttaa tggtttttca gaccgtaaga ttgctgaact ctggggaacg actgatgata
    18841 aagttcgcca acttcgcttg gaaaacaaga ttgttccagt ttataagatg gtagacactt
    18901 gtgcggcaga gttcgattcc gaaacgccat atttctattc aacctatggt tgggaaaatg
    18961 aatctatcaa atctgataaa gaatctgtac ttgtcctagg ttcaggtcca atccgtatcg
    19021 gtcaaggggt tgagtttgac tacgcaaccg ttcactctgt taaggctatc caggcagctg
    19081 gttatgaagc tatcatcatg aactcaaacc cagagaccgt ttcaacagac ttctctgtat
    19141 cagataagct ttactttgag ccattgacat tcgaagatgt tatgaacgtc attgacttgg
    19201 aacaaccaaa gggagttatc gttcagttcg gtggtcaaac agccatcaac cttgcagagc
    19261 cattggcaaa agcaggtgtg accatccttg gtacacaggt tgctgaccta gaccgtgccg
    19321 aagaccgtga cctcttcgag caagctctca aagaattgga tattccacag ccaccaggac
    19381 aaacggctac caatgaagaa gaagcagctc ttgcagctcg taagattggc ttcccagttc
    19441 ttgtccgccc atcttatgta cttggtggac gtgccatgga aatcgttgaa aacgaagaag
    19501 accttcgttc ttacatgcga actgctgtta aggctagtcc agaccatcca gttcttgtcg
    19561 actcttatat cgttgggcaa gagtgcgaag ttgatgccat ttcagatggt aaaaatgtac
    19621 tcattcctgg tatcatggag catatcgaac gtgctggtgt ccactcaggt gactcaatgg
    19681 ctgtttaccc accacaaacc ttgtcgcaaa aggttcagga gaccatcgca gactacacca
    19741 aacgcttagc aatcggtctt cactgccttg gaatgatgaa catccagttt gttatcaagg
    19801 atgaaaaagt ctacgttatt gaggtcaatc cacgtgccag ccgtaccgtt ccattcctat
    19861 ctaaggtaac caatattcct atggctcaag tagcgaccaa gctcattctt ggtcaaagtt
    19921 tatcagaact tggctaccaa aatggacttt accctgaaag cacccgtgtt catatcaagg
    19981 cacctgtctt ctcctttacc aaactagcta aggtagacag cttgctcggt cctgaaatga
    20041 agtcaacagg tgaagttatg ggttctgatg ctactttgga aaaagctctc tataaagcct
    20101 ttgaagcttc ttatctacac ttgccaactt ttggtaatgt cgtctttacc atcgctgatg
    20161 atgccaaaga agaagccttg aacttggctc gtcgtttcca aaacattggt tatggaatcc
    20221 ttgcgacaga agggacagca gccttctttg ctagtcatgg cttgcaagcc caacctgttg
    20281 gtaagattgg tgatgacgat aaggatatcc caagttttgt acgcaaagga agaattcaag
    20341 ctatcattaa cacagtagga acaaaacgaa ctgctgacga agatggtgag caaattcgtc
    20401 gttcagccat tgaacacggg gtgcccctct tcacagcgct agatacagct aatgccatgc
    20461 ttaaggtact tgaaagtcgt agctttgtta cagaagcgat ttaaatagaa aaataagata
    20521 tagcagactg
//
LOCUS       DAVKUR010000038        19460 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKUR010000038 DAVKUR010000000
VERSION     DAVKUR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.038"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            56..418
                     /locus_tag="VW749_001498"
     CDS             56..418
                     /locus_tag="VW749_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175520.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            953..1645
                     /locus_tag="VW749_001499"
     CDS             953..1645
                     /locus_tag="VW749_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0175521.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1698..4108
                     /locus_tag="VW749_001500"
                     /pseudo
     CDS             1698..4108
                     /locus_tag="VW749_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            4358..5059
                     /locus_tag="VW749_001501"
     CDS             4358..5059
                     /locus_tag="VW749_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175522.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5061..7769
                     /locus_tag="VW749_001502"
     CDS             5061..7769
                     /locus_tag="VW749_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0175523.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7865..8356)
                     /gene="tpx"
                     /locus_tag="VW749_001503"
     CDS             complement(7865..8356)
                     /gene="tpx"
                     /locus_tag="VW749_001503"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0175524.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8479..9408)
                     /gene="psaA"
                     /locus_tag="VW749_001504"
     CDS             complement(8479..9408)
                     /gene="psaA"
                     /locus_tag="VW749_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0175525.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9440..10288)
                     /locus_tag="VW749_001505"
     CDS             complement(9440..10288)
                     /locus_tag="VW749_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0175526.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10285..11007)
                     /locus_tag="VW749_001506"
     CDS             complement(10285..11007)
                     /locus_tag="VW749_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0175527.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11298..13190
                     /gene="pepO"
                     /locus_tag="VW749_001507"
     CDS             11298..13190
                     /gene="pepO"
                     /locus_tag="VW749_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0175528.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13313..13942)
                     /locus_tag="VW749_001508"
     CDS             complement(13313..13942)
                     /locus_tag="VW749_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0175529.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14958..17180
                     /locus_tag="VW749_001509"
     CDS             14958..17180
                     /locus_tag="VW749_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0175530.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17210..17653
                     /locus_tag="VW749_001510"
     CDS             17210..17653
                     /locus_tag="VW749_001510"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0175531.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17920..18105)
                     /locus_tag="VW749_001511"
     CDS             complement(17920..18105)
                     /locus_tag="VW749_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175532.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(18124..18537)
                     /locus_tag="VW749_001512"
     CDS             complement(18124..18537)
                     /locus_tag="VW749_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175533.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18668..19315)
                     /locus_tag="VW749_001513"
     CDS             complement(18668..19315)
                     /locus_tag="VW749_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0175534.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
BASE COUNT         5839 a         3668 c         4446 g         5507 t
ORIGIN      
        1 aaaagcaaat atgatacaat tttatttgaa aaaaaataaa aaaggagatt ttattatgaa
       61 atcaagtggt atcgtcggtc ttgtgggagg aattttactt cttatttgtc cttttgtctt
      121 gttgggaaca gcggtaaaca cagctgctac aactcttaat ggaggagcta ctgcaggggc
      181 tttttcaggt gttgccttac tcttgaatgc cttgaagatt gcaaatcttg ttcttggtat
      241 cattgctatt gtttactata aaggagataa gcgtgtaggt gcagctccgt ctgtactaat
      301 gattgtttct ggtgaagtta gtctcattcc attcttagga tgggttgggg ggattcttgc
      361 tattatcgga ggatctctat tccttgcaac attgaagaaa ttcaaatcag aagaataaaa
      421 ggtattttag catgaaaaga acaaaaaagt ttatcggtat aggagtagct ctattatctc
      481 tttctcttct agttgcatgt ggaacataaa gttcaaagaa tacttcaaca agtaatgatg
      541 agaagacagt agcaacatcc aatagttcaa aagaaacaat cactttcgat acaccggttg
      601 taacagacga tgcgattgaa tcaatacgca cttatgcaga ttatatagat ctttataaaa
      661 atatttttga tgattatttt actaaaactg aggaaggttt caaaggcaca gctatggaaa
      721 ataatgactc gtttactaaa ctaaaagagt caactcaaaa attattcgat gcgcagaaaa
      781 aaaggttaaa taatgaagat agaatagaaa caaccaaaaa caatgtgatt gccaaacatt
      841 gtcaaacagt cctttccttt ttggttttga ctagcttttt tgtgaaaaat tgtgtaaaat
      901 agaatagata aacgagggga aacctcggaa aatttaaagg agaatccatc taatggtaaa
      961 attggttttt gctcgccacg gtgagtctga atggaacaaa gctaaccttt tcactggttg
     1021 ggctgatgtt gatttgtctg aaaaaggtac acaacaagcg attgacgctg gtaaattgat
     1081 caaagaagct ggtatcaaat ttgaccaagc ttacacttca gtattgaaac gtgctatcaa
     1141 aacaactaac ttggctcttg aagcttctga ccaattgtgg gttccagttg aaaaatcatg
     1201 gcgcttgaac gaacgtcact acggtggttt gactggtaaa aataaagctg aagctgctga
     1261 acaatttggt gatgagcaag ttcacatctg gcgtcgttca tacgatgtat tgcctccaaa
     1321 catggaccgt gatgatgagc actcagctca cacagaccgt cgttacgctt cacttgacga
     1381 ctcagttatc ccagatgctg aaaacttgaa agtgactttg gaacgtgctc ttccattctg
     1441 ggaagataaa atcgctccag ctcttaaaga tggtaaaaac gtattcgtag gagctcacgg
     1501 taactcaatc cgtgcccttg taaaacacat caaaggtttg tcagatgacg agatcatgga
     1561 cgtggaaatc cctaacttcc caccattggt attcgaattc gacgaaaaat tgaacgtcgt
     1621 ttctgaatac taccttggaa aataaaaaat tgtaagtcta gaattgattt ctaggctttt
     1681 tatgttagta tggaagtatg ataaggaata aaaaacaaga ttatgtactg gcctacaagc
     1741 aaccagcttc aaccacttac atgggttggg aagaagaagc tttaccgata ggcaatggtt
     1801 ctttaggagc aaaagtattt ggccttatag gggctgaacg gattcaattt aatgaaaaaa
     1861 gtctctggtc tggaggtcca cttcctgata gttcagatta tcagggtgga aatcttcagg
     1921 atcagtatgt tttttagctg agattcggca ggctttggag aagagagatt acaatctggc
     1981 taaggaactg gctgagcagc acctaattgg gccaaaaacg agtcaatatg ggacctatct
     2041 gtcttttggg gatattcaca ttgagttcag ccagcaaggt acgactttgt ctcaggtgac
     2101 ggactatcag agacagctga atattagtaa ggcacttgcg acgacttctt atgtctataa
     2161 gggaacgcga tttgaacgtg aagcttttgc gagttttcca gatgatctct tggttcaatg
     2221 ttttactaag gaagggttgg aaactctaga ttttactata gaactatcct tgacctgtga
     2281 tttggcttct aatggaaagt atgaacagga aaagtctgat tacaaggagt gtaagttgga
     2341 tattactgat tctcatatct tgatgaaggg aagagttaag gataatgatc tgcggtttgc
     2401 tagttatcta gcttgggaaa cggatggaga tattagagtt tggtcatata gggttcagat
     2461 atcaggagcc agttatgcca atctcttctt ggccgctaag acggattttg cccaaaatcc
     2521 tgctagcaat tatcgcaaga aactagattt agagcaacag gtgagagact tggtggacac
     2581 agctaaagaa aagggctata cccaattgaa atcaaggcat atcgaggact accaagcctt
     2641 attccagcgt gttcaattgg atttggaagc tgatgttgac gcatccacta cagatgattt
     2701 gttaaaaaat tataagccac aagaagggca ggctttggag gagctgttct tccagtatgg
     2761 acggtattta ttgattagtt cgtccagaga ctgcccagat gctctaccag ctaacctaca
     2821 gggagtctgg aatgcggtcg acaatcctcc ttggaattcg gactatcact taaatgtcaa
     2881 tctgcagatg aattattggc cagcctatgt taccaatctc ctagaggcgg tctttccggt
     2941 catcaactat gtagatgatt tgcgtgtcta tggtcgtcta gcggctgtaa agtatgcagg
     3001 aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt catactcaag cgactccctt
     3061 tggttggacg gcacctggtt gggattacta ttggggttgg tcaccagctg ccaatgcgtg
     3121 gatgatgcaa accgtttatg aagcctattc attttatagg gaccaagact atctcagaga
     3181 gaaaatttat cccatgttga gggaaacggt tcgtttttgg aatgcctttt tacataagga
     3241 tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc ccagaacatg ggccgatttc
     3301 gattggcaat acttatgacc aatctctaat ttggcagtta tttcatgatt ttattcaggc
     3361 tgctcaggaa ttgggactgg atgaggactt gttgactgag gttaaggaga agtctgattt
     3421 actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg gagtggtatg aggaggaaga
     3481 gcagtatttt caaaatgaga aagtggaggc ccagcatcgg cacgcttccc atctagtggg
     3541 actctatcct ggcaatctct ttagctacaa gggacaagag tatattgaag cggcgcgtgc
     3601 tagcctcaat gatcgtggag atggcggcac aggctggtcc aaggctaata agatcaatct
     3661 ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta ttggcagagc agttaaagac
     3721 atccaccttg ccaaatcttt ggtgtagcca tcctcctttt cagatagatg gtaattttgg
     3781 tgctactagt ggcatggcag aaatgttact ccagtctcat gcagcttatc tggtacctct
     3841 agctgcccta cctgatgctt ggtcaacagg ttctgtttca ggcttaatgg cacgtggaca
     3901 ttttgaagtg agcatgagct gggaagataa aaaactctta cagttgacca ttttatcaag
     3961 gagtggagga gatttgcgag tttcttatcc agatattgag aagagtgtga ttaaaatgaa
     4021 tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt atttcggtgg caacagcaga
     4081 aggtgatctt gttcaatttt atttttaaga agatgttata aggcagtaat ttgaaactgc
     4141 cttttaataa ggatttaaga atataagcag ttttcaacta gttgaaaaag cgttataatg
     4201 ataataggaa gtaatactca atgaaaatca aagagcacaa acaaggaagc tagccgcagg
     4261 ttgctcaaaa cagtgttttg aggttgcaga tggaagctga cgtggtttga agagagattt
     4321 tcgaggagta taatttgttt gatagagggt gggtctgatg gcttatattg agatgaaaca
     4381 ctgttacaag cgttatcagg ttggggacac ggagattgtg gccaatcgtg atgtgaattt
     4441 tgagattgaa aagggggagc tggttattat ccttggtgct tcaggtgcag gcaagtcaac
     4501 agtgcttaac cttcttgggg gaatggatac caatgatgaa ggggaaatct ggattgatgg
     4561 tgttaatatt gcggattata gttcccacca gcgcaccaat taccgtagaa atgatgtggg
     4621 gtttgttttt cagttttata atctagtttc taatctgaca gctaaggaaa atgtggaact
     4681 ggcttctgaa attgtgacag atgtcttgaa tcctgatcag gtcttgacag atgtaggtct
     4741 ggctcatcgt ctaaataact ttccagccca gctttctgga ggggagcaac agcgagtctc
     4801 cattgcacgc gcggtagcca aaaatcctaa aattcttctt tgtgatgaac ctactggagc
     4861 cttggattat cagacgggca agcaggtttt gaaaattctc caagatatgt ctcgtcaaaa
     4921 gggagcgacg gtgatcatcg tgactcataa tggagctttg gcgcccattg ctgatcgcgt
     4981 gattcatatg cacgatgcca gtgtcaagga tgtggtgctc aaccagcatc ctcaggatat
     5041 tgacagtttg gagtactagt atgatcaagc gaaaaactta ttggaaggac ttaattcagt
     5101 ccttcacagg ctccaagggg cgttttttat ccatcttgat cctgatgatg ttgggatctc
     5161 tagccttagt aggcctcaaa gtaaccagtc ccaacatgga ggcgacagct aatgcttatt
     5221 taacaactgc tcaaaccttg gatttggcag tcatgtctaa ctatggcttg gatcaagcag
     5281 accaagaaga actaaaacag acggagggcg cagaggtcga gtttggctat ttgacagatg
     5341 tgactatgga taatgggcag gatgccattc ggctgtactc caaaccagag cgaatttcaa
     5401 cctttcagct aagaaaggga cgacttcctc agtcagacaa ggaaatcgct ttggccactc
     5461 atttgcaagg ccaatgcagc gtgggacagg agattagttt taaagaaaaa gaagagggtc
     5521 attcctcttt aaaagaccat acttatacca ttactggttt tgtggattcg gctgaaatcc
     5581 tctcccagcg agatatgggc tacgcaggaa gtggaagtgg gactctgaca gcctatgggg
     5641 tgattttacc tagtcagttt gatcagaaag tctacaatat agctcgtttg aaatatcaag
     5701 atttagcagg tttaaatgcc ttttcatcag cttatgaaga aaaatccaag caacatcagg
     5761 aagaccttga acaaacttta tcagataatg gcaaggtacg tctgcaactt ttgaaaaaag
     5821 aaggacaaga gtctctagac aaggggcaag agacccttga caaggctcag actaatttgc
     5881 aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat acaggctcaa gaaagtcaac
     5941 tagccttgtt tcctcaagtt cagagagagc aggctagtgc tcaacttacc caagccaagc
     6001 aggaattggg caaggaagaa gacaaactaa agcaagctga acaaaatcta gcccaagaaa
     6061 aggaaaaatt agaaaaacat cagcaagtct tggacgattt ggcggagcca aggtatcagg
     6121 tctataatcg tcagaccatg ccaggtggtc agggctatct tatgtatagc aatgcttcat
     6181 ccagtattcg agcagtgggc aatatctttc ctgtggtact ttatgccgta gcagccatgg
     6241 tgacctttac gaccatgact cgctttgtag acgaagagcg aactcatgca gggattttta
     6301 aggccttggg ttaccgtagt aaggatatta tcgccaagtt tctcctttat ggactagtag
     6361 ctgggactgt cggaacggct ctaggtagta tacttggtca ttatttgcta gccagtgtaa
     6421 tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac ccagattcag ttctattgga
     6481 cctatagctt actagctctt gtcttgagct ggttggcgag tgtgttacca gcctatctgg
     6541 tggcttggag ggaacttcat gccgaagcag cccagcttct acttcctaaa cctcctgtca
     6601 aaggagctaa aatcttattg gagcgtatcg gttttatctg gcgtcgtctc agttttactc
     6661 ataaggtaac agcccgcaac atctttcgtt ataagcagag aatgttgatg acaatctttg
     6721 gtgtggcagg ttctgtagct ctgctctttg caggtttggg aatccaatct tctgtagcag
     6781 gagttccgtc taaacagttt caacaaatcc aacagtatca gatgcttgtc tctgaaaatc
     6841 ctagtgcgac cgatcaggac aaggtagagc tagcagaagt gttgaaaggg caggagatac
     6901 tagcctacca gaaaatctat tctaaaacgc tagacaagga tttcaaaggc aaggctggtc
     6961 ttcaaaacat tactcttatg atgatagaga aggaagattt gactcccttt atccatcttc
     7021 aacatcatca gcaggagctg acattaaaag atggcatcgt tattacagct aaactcgccc
     7081 agctggcagg tgtcaaggtt gggcagactt tagaaattga aggtaaggaa ctaaaggtcg
     7141 ctgctattac tgagaactac gttggtcact ttatttatat gagtcaggct agctatgagc
     7201 aactttacgg acagctaccc caagccaaca cttatctggt ctcattaagg gataccagtg
     7261 caactagtat cgaaagtcag gcgggcttgc ttatgagtca atctgcggtg tccagcgttg
     7321 tccaaaatgc ttcagccatt cgactcttcg actctgtcgc tagctcactc aatcagacca
     7381 tgaccatctt ggtcatcgta tcggttctat tagctattgt catcctttac aatctgacca
     7441 atatcaacgt agctgagaga atccgtgaac tctccactac caaggttctt ggttttcata
     7501 ataatgaagt caccctctac atttaccgtg agacgattgt gctatccctt gtgggaatcg
     7561 tacttggtct ggtagctggt ttctatttac accaattttt gattcaaatg atttcgcctg
     7621 cgactattct cttttatccg caggtaggct gggaagtcta tgtaatccca gtggcagcag
     7681 taagcatcat tttgaccttg cttggtttct tcgtcaatta ttatctgaga aaggttgata
     7741 tgttagaagc cctgaaatct gtagagtaag gtagttattt ttagctgatt gaacttctat
     7801 ttactaatat tcaaaaatcc tccgtttcaa agagcaggga actctttgtg acagaggatt
     7861 ttttctatag ggctttagca gctgcaattg cggcttcgaa gtttggctca gaattgatat
     7921 tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc gaggacaaag actgcgcgtg
     7981 ctaataggtg ccattcgttg atcaagaggg cataatcgcg cccgaaagaa tggtcaaagt
     8041 agtctgaaag cataatggca ttgtcaaggc cttcagcacc gcaccaacgt ttttgagcaa
     8101 aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc cagtccagcc aattcttcat
     8161 taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat agaaggaacg acactcaaga
     8221 cttttttctt gccatcaaaa tcagccagag attttttaga aagatctgtt gtagtaagag
     8281 aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc tgtaaagctc acaggatttc
     8341 cgagaaaagt taccatagga tactccaatc ttttttcttc cattgtatct gaaacagtca
     8401 gaattttcca atgatttgac cggaaatgtg ggcatagaaa aaacgccagc tcacatgaga
     8461 atgacgtttt tcagaggctt attttgccaa tccttcagca atcttgtcaa ggttgtattt
     8521 catcatgctg tagtagctgt cgccttcttt accttgttct gcgatagagt cagtaaagat
     8581 ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt ttcattggac ggtcatccac
     8641 acttgattct acaaagagtg atggaacttt tgtttggcga agtttttcaa ccaaggtctt
     8701 gatttgttca ggagttcctt cttcttcagt attgatttcc cagatgtagg cacttgggac
     8761 accataggct ttagagaagt atttgaatgc tccttcgctg gttacaatga gtttcttttc
     8821 agcagggatc ttattaaatt tatccttact ttctttatca agtttgtcta acttatcagt
     8881 atattctttg agattttttt catagaattc tttattgtta gggtctttgg cgctcaattg
     8941 tttggcgata tttttagcaa aaataatacc gttttcaagg ttaagccaag cgtgtgggtc
     9001 ttcttttcct ttttcatttt gaccttcaag gtagataaca tcaacgccgt cgctgactgc
     9061 gaagtagtct ttgttttcag ttttcttggc attttctacc aattttgtaa accaagcatt
     9121 gccacctgtt tcaaggttga taccgttata gaaaatcaaa tcagcctcag aagttttctt
     9181 aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc ccaatcggaa cgatactatg
     9241 aaggtcaatt ttgtcaccag caatattttt agtaatatca gcgatgattg agtttgtagc
     9301 aacaactttt agtttttgac cagaagttgt atcttttttt ccgctagcac atgctacaag
     9361 aatgattgca gaaagaaaga gaacgagtaa tgtacctaat tttttcatta gatcctccaa
     9421 tttattaggg ctttgcccct tattttaaca aatgtttatt tttcagtttc aaatatcgtt
     9481 gtttgggagc gataaagaag ctaatgagaa agaaactagc agctgtaagc acgatactag
     9541 aacctgccgc aacattaaaa ctatagccaa taaagagtcc caaaactgaa gcagtagctc
     9601 cgaaggttga ggaaaggaaa atcatgcttt tcagactatt agcatacaga taagcagttg
     9661 cagctggggt aatcagcatg gctacaatca ggatagttcc gacactttgc atggctgtca
     9721 cagacacgag agtcaggagt accatgagaa ggtagtgata gaaattgaca ggcattccca
     9781 tggctttagc caagagttca tcaaaggaag ttatcaagag ttgcttgaag aaaatccaga
     9841 ttaacaagag gatggctgcc cccacaccca tagtaataaa catatccgta tcttggacgg
     9901 ccaggatatt accaaaaagg atatggaaaa ggtcagttga acttttagcg acaccaatca
     9961 agatgatacc gagggctaag aaagaagaaa aggtaatgcc gatggcggta tcgcttttga
    10021 taatcgagtt tcctttgatg taggtaatga tgatggcagc tagcaatcca aagacaatgg
    10081 ctccgataaa gaagtcaagg cccaagatga aggagagggc tacacctggt aagacagcat
    10141 gtgaaatggc atctcccatg agtgacatcc cgcgtagaat aatgaaacat cccacggctc
    10201 cagctacaat cccgacgaca atagctgtta tcaaggcatt ttgtaggaaa tggaattttt
    10261 gcaatccatc gataaattct gcaatcatag gtcacctcca ttgaaaaaga gttgattacc
    10321 gtaagcttct tttagattgg tttcggtaaa agtttctttt gttggaccaa aggcaatcac
    10381 ttctcgattg acaagtaaga cttgatcgaa gtagtgggga atcttgctga ggtcgtggtg
    10441 aacgatgaga accgtcttcc cagctttttt caaatctctc agcgtattca tgatgatttc
    10501 ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag aggatatagt cggcttcctg
    10561 caccaaacat ctggcaatca agacccgctg gaattgacct ccagacagtt gactaatttg
    10621 acgttcagcg tagtcagcta ggccgacgat ttcaagggcc tcttgcactt tcttccaatg
    10681 tttagccttt aaacttcgaa agagaggaat agagggaaat agtcctaacg agacgcattc
    10741 cttgaccttg atgggaaagt tgtagtcgat attgattttt tgttcgacat aggcaattcg
    10801 gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc tgaccttgat gtgggataat
    10861 tcccaacata ccttttaata gtgttgattt cccagcgccg tttggaccaa tgatgccggt
    10921 aattgttggt ccatggagca ctagtgaaat atccttaagt gccaacgttt ctttgtagga
    10981 gacactgagg ttttcgatac gtatcataaa cttgtattcc tcctgtctct taatatacat
    11041 taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta aaataataac tgaaaaatag
    11101 attctaaaaa taactttcag gataaatttc taaattataa aacgcatagt atcaagtgta
    11161 aaaaacttgg aattatgcgt tttatcatgg aaagattttt tataatagct aaaaaataat
    11221 agttaaatgg ttattaattg cattccctag tgatttttgt taagataaat gcaaatacaa
    11281 atgaaagcga gaacaagatg acacgttatc aagatgattt ttatgatgct atcaatggag
    11341 aatggcaaca gacagctgaa atcccagcag ataagtctca aactggaggt tttgttgatt
    11401 tagaccagga aattgaagac ctgatgctgg cgacaacaga caagtggtta gcaggtgaag
    11461 aagtgcctga ggatgctatc ttggaaaact ttgtcaaata ccaccgccta gttcgtgatt
    11521 ttgacaagag agaagctgac ggtatcacac ctgtcttacc actccttaaa gaattccaag
    11581 aattggaaac ttttgcggat tttacagcta aactagcaga gtttgagctt gcaggaaaac
    11641 caaacttcct tccttttggt gtatcgccag actttatgga tgctagaatc aatgttctat
    11701 gggctagcgc tccaagcaca atcttgccag atacgaccta ctatgcagaa gaacatcctc
    11761 agcgcgaaga gctcttgact ctttggaaag aaagcagcgc aaatctcctc aaggcttatg
    11821 atttctctga tgaagaaatt gaagacttgc tagaaaaaag acttgaattg gaccgccgag
    11881 ttgcggcagt ggtgctctct aatgaagaaa gttcagaata tgctaaactc tatcatccat
    11941 attcttacga agattttaag aaattcgcgc ctgccctacc tttggatgac ttcttcaaag
    12001 cagttattgg gcaattacca gacaaggtta ttgtagacga ggaacgtttc tggcaagcag
    12061 cagagcaatt ctacagtgag gaagcctggt ctctccttaa agcaaccttg attttgagtg
    12121 ttgtcaatct ttcaaccagc tatttaacag aggatatccg tgttttgtct ggtgcctaca
    12181 gccgtgccct ttctggagtt ccagaggcaa aagataaggt caaagcagct tatcatctag
    12241 cacaagaacc tttcaagcaa gccctgggtc tttggtacgc ccgtgagaag ttctctccag
    12301 aagccaaggc ggatgtggag aaaaaagtgg caaccatgat tgatgtctat aaggagcgtc
    12361 tgcttaagaa tgactggctc actccagaaa cctgtaaaca ggctatcgtg aagctcaatg
    12421 tgatcaaacc ttatattggc tatccagaag aattgcctgc acgttacaag gataaggtag
    12481 tgaatgaaac tgccagtctt tttgagaatg ctctagcctt tgcgcgtgtg gaaatcaagc
    12541 acagttggag taagtggaac cagcctgtag actataagga atggggcatg cctgctcata
    12601 tggtcaatgc ctactacaat cctcagaaga acctgattgt ctttccagcg gccattttac
    12661 aggcgccttt ctatgacttg catcagtcat cttctgctaa ctacggtggt attggggcag
    12721 tgattgccca tgaaatttcc cacgcctttg atactaacgg ggcttccttt gacgaaaatg
    12781 gtagcctcaa ggattggtgg acagagagcg actatgctgc cttcaaggag aaaacacaaa
    12841 aagtcattga ccaatttgat ggacaggatt cttatggagc aaccattaac ggtaaattga
    12901 ctgtatcaga aaacgtggct gacttgggag gaatcgcagc agcgcttgaa gcagctaaga
    12961 gagaagcaga cttctcagca gaagagttct tctacaactt cggtcgcatc tggcgcatga
    13021 aaggtcgacc agaatttatg aaacttttgg ctagcgtcga tgtgcacgca ccagccaaac
    13081 tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt tacaacctat gatgtcaaag
    13141 aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat tatttggtaa tacaaaaaat
    13201 ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac cttgatagga tgccttttgt
    13261 aatagaaaga tttgctggat agtttactta aatttcgatt gtcatcatct tgctagaaaa
    13321 agggattgaa ggccttttcg tgagcgatag tagtagctgg accatgtcct ggatagacat
    13381 cgtagtttgg tagggtgaag agttgggtct ggatactatg aaggagttgc tccatgctac
    13441 cagtcggaag gtcggtccgt ccgatagttt cgcggaatag agcatctccc gtcaagacta
    13501 ggtgagcatc aggaaagact agggaaacac caccgataga gtgccctggg gtcggtagaa
    13561 ccttaaaacg aaattcctct agttggtatt cttcgtgaaa gacaaaggtg tgttctgcag
    13621 gttttgtgac cacatctgcc atatcatcgt ggcgagggag accggagaga ttatcgacag
    13681 gagtgtagag ccagctggct tcgctctctg cgatatagac aggaggattg ccaaacgtct
    13741 cgcgaaccaa gtccagactc atgatatggt cataatgggc gtgggtcaag agaatagcac
    13801 agatcggttt gttgatcttc tcgattgtct gacgaatggc ttcccaatga ctaccaggat
    13861 cgacgacgat gaggtgcttt tcgccttcta gataataggt attttcatag gcaacaggat
    13921 tcacggtttt atggattttc atactagctc caatctcaaa gaatgtacta atactcttcg
    13981 aaaatctctt caaaccgcgt caactttatc tgcaacctca aagcagtgct ttgaacagcc
    14041 tgcggctagc tttctagttt gctctttgat tttcattgag tataaattaa gtatagcaca
    14101 gttagggaga ataggtaagg atttaaaatg aacttaaaaa ccagcatgac tagatgaaga
    14161 caggctggtt atcaatttat caatattgga aaggtgtcaa ttgcccttca taggttgcat
    14221 aaactccgtc attagcttgt ttgatagacg tgatgtttag agtgctaccg tagttggctt
    14281 atcatttgtc gctatattca ctataagtta tcctactggg caggttctgg tcgttagcat
    14341 agtattgaac gagtttttta tagctttgct ggctgaatag gaacaggcag caaactccta
    14401 acattaggag agcaaagata gaaatagcag tttttttcat aggtattctc cttataaact
    14461 aaaggataga agaaagtatc ttgaggattt ttatactctt caaaaatctc ttcaaaccgc
    14521 gtcaacaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    14581 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    14641 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    14701 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    14761 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    14821 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    14881 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    14941 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    15001 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    15061 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    15121 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    15181 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    15241 gtcctgatgt gcgggtgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    15301 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    15361 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    15421 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    15481 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    15541 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    15601 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    15661 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    15721 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    15781 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    15841 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    15901 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    15961 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    16021 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    16081 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    16141 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    16201 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    16261 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    16321 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    16381 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    16441 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    16501 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    16561 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    16621 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    16681 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    16741 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    16801 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    16861 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    16921 accctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    16981 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    17041 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    17101 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    17161 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    17221 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    17281 tcagggactt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    17341 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    17401 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    17461 tactaagaga ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    17521 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    17581 tggagcagat atgcaggttg agctggttaa taatggacct gttaccatta tcctagatac
    17641 taaaaagaga taagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    17701 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    17761 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    17821 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    17881 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    17941 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    18001 caaaatccag tcccaagtaa gccccctttt aaatgtcaaa aatgccagca tgattccatc
    18061 aatgacaagg agttgaatgg ttttgatgaa gatgattttt ttcatgctaa aacctccttt
    18121 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctct
    18181 taggtagtca gctgtcatat aataaaaagt agaatggcaa gcagtgatga ttggcataag
    18241 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    18301 gagaacccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    18361 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgagcaa ggaagaaaat
    18421 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    18481 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    18541 aagacctccc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    18601 atgataaaaa tagcagaagg gagattctct taagttggct agtattcttt atttgagttt
    18661 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    18721 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    18781 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagttttaat gcattcaaag
    18841 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    18901 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    18961 tgatggccgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    19021 cttcccactt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    19081 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    19141 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    19201 cgttggttac ggaaatcaat ccaaagggta caagagctgt ccatgatccc cagtctacaa
    19261 atttatcgag gtgtgagttg aggtaaccag atgcaatcgc aatcccaacg accaaagcaa
    19321 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    19381 aaactacctt tctttttttc aaatattctc ccaccaaatg aaagtaaaat aaaatgatag
    19441 aaataaaacc ctgaaaataa
//
LOCUS       DAVKUR010000039        18197 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKUR010000039 DAVKUR010000000
VERSION     DAVKUR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18197
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.039"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(85..1020)
                     /locus_tag="VW749_001514"
     CDS             complement(85..1020)
                     /locus_tag="VW749_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0175535.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1017..1877)
                     /locus_tag="VW749_001515"
     CDS             complement(1017..1877)
                     /locus_tag="VW749_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0175536.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1985..4147
                     /locus_tag="VW749_001516"
     CDS             1985..4147
                     /locus_tag="VW749_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0175537.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4239..5498
                     /locus_tag="VW749_001517"
     CDS             4239..5498
                     /locus_tag="VW749_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0175538.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5512..6378
                     /locus_tag="VW749_001518"
     CDS             5512..6378
                     /locus_tag="VW749_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0175539.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6392..7225
                     /locus_tag="VW749_001519"
     CDS             6392..7225
                     /locus_tag="VW749_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0175540.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKLTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7226..7306
                     /locus_tag="VW749_001520"
                     /pseudo
     CDS             7226..7306
                     /locus_tag="VW749_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7583..9025
                     /gene="gtfA"
                     /locus_tag="VW749_001521"
     CDS             7583..9025
                     /gene="gtfA"
                     /locus_tag="VW749_001521"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0175541.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9163..10356
                     /locus_tag="VW749_001522"
     CDS             9163..10356
                     /locus_tag="VW749_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0175542.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11043..13022
                     /locus_tag="VW749_001523"
     CDS             11043..13022
                     /locus_tag="VW749_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0175543.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13089..14585
                     /locus_tag="VW749_001524"
     CDS             13089..14585
                     /locus_tag="VW749_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175544.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14585..15511
                     /locus_tag="VW749_001525"
     CDS             14585..15511
                     /locus_tag="VW749_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175545.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15520..16587
                     /locus_tag="VW749_001526"
     CDS             15520..16587
                     /locus_tag="VW749_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175546.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16598..17524
                     /locus_tag="VW749_001527"
     CDS             16598..17524
                     /locus_tag="VW749_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175547.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17599..>18197)
                     /locus_tag="VW749_001528"
     CDS             complement(17599..>18197)
                     /locus_tag="VW749_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0175548.1"
                     /translation="TVSLPNAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEHKA
                     IKHYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFH
                     FQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLI
                     KLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5354 a         3227 c         3829 g         5787 t
ORIGIN      
        1 caataaaact tcagatccgt aaaacttaat tgaattacta atctgaagtt atttttatat
       61 cgtttatatt ataattgtgt tattttactt ccaactattg agagaaattt cgccactatt
      121 tagccagatt tcttttccgt tatcacattg aactaaaagt tttccatttt ctgagatgtc
      181 tttagcaagt cccttgtagt ctttttgctc tagtgtgaaa gtgacttctt ttcctagaat
      241 gaatgactgt tttttgtata ggtataatag ctcttctgct ggtgtttcga agaaagcacg
      301 ccagatttct atgatcaatt cattccttgt tataggagct gtagctttaa ataagctggc
      361 agctttttct tttaattcct gagggaagtc tttaatagtg aaattgatac ctactccaat
      421 aatgatatct gtgactaagc cagtttctac agaggtcatt gcttcagtaa ggattcctcc
      481 aattttatga ttgtttagat agatatcatt gacccatttt atgtcgacat ctattaaagt
      541 taggttctta atggctttgt agacagctcc agctacaagt agtgtgtagg atggtaattt
      601 gtcatagggg agatttggtt taagatggag tgtcatataa ataccacctt gtggtgagta
      661 gaaggaacgt tgaaaacggc ctcggcctgc tgtttgatag gaagctagat agagggtatt
      721 tgcttcatgg cctaaatcaa ttgcttcttt tgcatctagt tgtgttgatt ttgtttcggg
      781 tttaaagctg actttaattg gaagattttc ttctagaatc tctggaagaa taaggtcacc
      841 attcatcagt ttatatcctc tatttttgat actatcaatt tcaatgcctt cttgttctag
      901 tcgcttgatg gctttccaaa ttgctgttcg gcttagggat agtttttctg cgattttttc
      961 tccgctgata tagtcggttt ctttagatag gatttggtag acagcttggt aggatttcat
     1021 aatgttgcct ttcttactag ttggtattga gagtattctt ttcttgtatg acttggagtc
     1081 tgattaaagt attgtttata agctttcgaa aaatggagtg gatctgaaaa acctaccgag
     1141 tatgcaatta ccttgatgga ctcttgggta ttttcgagaa gttgtctagc tcggtgcatt
     1201 cgaacgtaga gtaggtattc tttgggtgat aaggtattaa attctttgaa tacgcttgat
     1261 aagtagcttc tgtgaacgga tagttctttt gctaaatctt gaattgtaag tgattgagga
     1321 tagtggctat caattaatcg tttgcattca agatagagtt ggtgggttga tgaaatattc
     1381 ttttttttct gattgggagc aatagttccc agatgaaaca tcagttcatg aagttgtccc
     1441 atgatatgga gttgagctaa ttcacttgat tttgtaatct gagcgaagcg gacaatgtct
     1501 gagatgagtt ttgcagtagt ctgggtatga caagtttcag attggatgag ataggattga
     1561 tcagaaattt gggaaagagc aaaataatca ggggctttcc ctccagtgat tcctaaccag
     1621 tagtaggccc aaggttcttt actatctgct tgataaaagg ttagttcctc tggttttaat
     1681 agaaagaaat ctccttcttt taaatcaaca attttaccct tgtaatgaaa ttttccttgt
     1741 cctttagtaa tgtaatgtag gacgtatgta tcacgaatgg ctggaccaaa agagtaatta
     1801 ggtgtgcatt cctcatatcc ataaaagctt agggcaaggt cgattgttcc agtctggtat
     1861 tctgaaaaaa ctaacatgtg ctacctccta cctaacattt taccatattc ttgagacatt
     1921 tttctatttt ggaaagcgat ttcaggtgat aaaatagagt caataaagtg atgaggtgaa
     1981 gtaaatggga gttaggatag agaataatct attttatgtt gagagtaaaa atctaagttt
     2041 gattattgaa aatcgaaatg gctacttact tttgaaacat ttaggaaaga ctattaagaa
     2101 ctataaaggt tccaatagtg tttatgaacg agaccatgcc ttttcaggaa atccaacagc
     2161 tactaatcga acctttagtt tagatactca acgtcaaatt tttggacaac atggcttagg
     2221 agattttagg aaaccaacca tacaggttca gcataatgta actgaagtaa cagactttcg
     2281 atttgtagaa gcaaagattt taaaaggtca gaatggtcca cagggcttac cttctccaca
     2341 tagcatggac gatacagaga ctcttgtctt aatgttagaa gattctaagg ctcaacttag
     2401 tctgactttg tattatacta cttttaataa tgatgcgact attgctagct acagtaaatt
     2461 agataataat agtaatcagg aagttgtcat ccataaagat ttttctttta tggctgattt
     2521 tccagctgca gattacgaaa tagtaactct gcagggtgct tatgctcgtg aaaagactgt
     2581 tagacgtcaa caggtagaac aaggaatctt ttcgattagt tcaaaccgag gtgcttctgg
     2641 tcatgctcaa acaccagctc ttctactatg cgaacaagga gtcacagagg atgctgggaa
     2701 tgtgtttgct attcaactaa tgtatagtgg caactttgaa gcttttgttc aaaaaaatca
     2761 attgaatgaa gttcgggtgg ctattggcat taatccagaa aacttttctt ggaagttagc
     2821 ccctgaggaa tactttgaaa caccggtagc tttagtgact cattcagatc agggattaac
     2881 tggtattagt catgaaagtc agaattttgt actgaagcac attatgctaa gtgaattttc
     2941 taaaaaagaa cgtccaattc taatcaataa ctgggaagct acttactttg actttcagag
     3001 agaaaaactg ttagagttag cagatgaagc taagaaagtt ggcattgaac tttttgtatt
     3061 agatgatggt tggtttggca atcgttttga tgataatcgt gctttaggtg attgggttgt
     3121 taatgaggaa aaactgggtg gaagtctaga aagtctgatt tcagctatcc atgaaagagg
     3181 tttgcagttt ggactttggt tagaacccga aatgatttct gtagatagtg atttgtatcg
     3241 tcaacatcct gactgggcta ttcaggttcc tggctatgag catacttatt ctcggaatca
     3301 attagtactt aatcttgcca atcctcaggt agtagaatac ttgaaaagtg tcttagatca
     3361 actcctatct tatcatgaga ttgattacat taaatgggat atgaaccgca atatcactaa
     3421 gctagggaat ggattaactt atctagagac acagatgcaa tctcatcagt acatgctggg
     3481 gctttatgaa ctcgtttctt atctgacaga gaagcacagc catattctct ttgagtcctg
     3541 ctctggtggt ggtggacgaa atgatcttgg tatgatacgc tatttcccac aagtctgggc
     3601 tagtgataat actgatgcca ttgcacgttt accaattcaa tacggttcat cctatttcta
     3661 tccaaccatt tctatggggg ctcatgtgtc agcagtaccg aatcatcaga tgggacgaat
     3721 gacaccatta gaaacacgtg gccatgtagc aatgatggga aatttgggct atgagcttga
     3781 tttgacaaat ttatcagatg aagagaaagc tacgattgct aatcaggtga acttgtataa
     3841 agaattacga ccagtagttc agttaggaca gcagtataga ctaattaatc ctgatactgc
     3901 atccaatgaa gcagctgtac aatttaatta cggaaatcaa acgattgtaa cctacgttcg
     3961 cgttttatct gttgtagaga ccatggaaac aactttaaaa ttaaaagatt tggatgaaga
     4021 gggactatat aaattacagg aaaatggcga agtttactca ggtgcagaac taatgtatgc
     4081 gggcttaact gttatcttat cccaaggaga ttttttgagt agacagtata tttttagaaa
     4141 actatgatat gtactgaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     4201 tcaataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat aaaaaaatcg
     4261 gacttcttgc aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta
     4321 aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa
     4381 ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg
     4441 tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg
     4501 atgtggtcaa tatttaccca cagtccattg aactgcaaga atgggcaaaa gcaggtgttt
     4561 ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat
     4621 atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact
     4681 acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg
     4741 aacagttagt caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag
     4801 atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa
     4861 aagaagcaaa tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga
     4921 ttatgaaaga tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga
     4981 actgggaagg tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca
     5041 tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga
     5101 ttgggacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag
     5161 acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg
     5221 aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag
     5281 cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg
     5341 cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc
     5401 ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc aatgatttga
     5461 atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa
     5521 gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt
     5581 ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg
     5641 acttacaact acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa
     5701 ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt
     5761 gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc
     5821 cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag
     5881 caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa
     5941 accagtcttt tagggactag gtggggagca atctttgcgg ctgtctttgt ccttctttgg
     6001 caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag
     6061 attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa
     6121 ttgccttact tgctaccaag tgtctctata gtctttatcc tagccctaaa aggtgggctg
     6181 actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca
     6241 cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc
     6301 attgccgtaa tcttgttctt cttaattgta gtgatttcga tcatccaatt gagagtatct
     6361 aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat
     6421 tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac
     6481 cctctttagt tccttcaaac tcactaagga tattgtagat aatttctttg gctttccaac
     6541 caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag gctattattg
     6601 gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc
     6661 agcctactcc atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct
     6721 cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat
     6781 gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat
     6841 tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga
     6901 tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc
     6961 aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga
     7021 cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt
     7081 ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt
     7141 ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg
     7201 aatgagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct
     7261 agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa
     7321 ccatacctac ggtaaggtga agctgacgtg gtttgaagag attttcgaat agtataagaa
     7381 gagctcatgg aatctatagt ctttgacaca gaggaagagt tcagcttgtt gataattcta
     7441 tgtagaaaac aagaaagtag tactttgttt atcacagtct atattagtac gagtttgatg
     7501 ataaatagag atttaaaatg aattttattt atgaagccag atcatatgag acttggcttc
     7561 aattagaaaa aggagagtaa tgatgccaat tcaaaataaa accatgttga ttacctattc
     7621 tgatagcctt ggaaataatc ttaaagactt atatgataat ttggaagagc attttggaga
     7681 tgctattgga ggagttcacc ttttaccatt tttcccatca acaggtgatc gtggatttgc
     7741 gccagttgac tacgacgaag tggactcagc ttttggtgat tgggaggatg ttaagcgttt
     7801 aggtgagaga tattatctta tgtttgattt tatgattaat catatttctc gtcaatccaa
     7861 gtattataag gactatcaag aaaaacatga agccagtgaa tttaaagatc tctttttaaa
     7921 ctgggataag ttttggccag aaaaccgtcc gacacagtct gatgtagatt taatttacaa
     7981 gcgtaaggat cgtgcaccaa agcaagagat tgtgtttgaa gatggttcag tggaacattt
     8041 gtggaatacc tttggtgagg agcagattga tcttgatgtg accaaagaag taactatgga
     8101 atttatccgt aagaccattc agcacttggc aagtaatggg tgtgatttga ttcgtctaga
     8161 tgcctttgct tatgcagtga agaaattgga tactaatgat ttctttgtgg aaccagatat
     8221 ttgggattta ttggacaaag ttcgagatat cgctgctgag tatgggacag agcttttacc
     8281 tgagattcat gaacactatt cgattcagtt taaaatagca gaccatgatt actatgttta
     8341 tgattttgct cttccaatgg tgacacttta tactctttac agttccagaa cagagcgttt
     8401 ggctaagtgg ttaaagatga gcccgatgaa gcaatttacg acgctagata cccatgatgg
     8461 gattggagta gtagatgtca aggatatcct gaccgatgag gagattgact atgcttcaaa
     8521 tgaactctat aaggttggag ccaatgtcaa acgtaagtac tctagtgccg agtataacaa
     8581 cttagatatc taccaaatca attcaaccta ctattcagcg cttggagatg atgatgtcaa
     8641 gtattttctc gctcgtctaa ttcaagcttt tgccccaggt attcctcagg tttactatgt
     8701 gggtctatta gcaggcaaga atgacttgaa attattagaa gaaactaaag aaggtcgaaa
     8761 tattaatcgt cattactata gcaacgagga aatagcaaaa gaagtgcaac gatctgttgt
     8821 gaaggccctt ctcaatctat tttctttccg taaccgttca gaagcctttg atctagaagg
     8881 gactattgag atagagacac caacagttca cagcattgta atcaaacgtc aaaataaaga
     8941 taagtccgta acagcagtag cagaaattga tttgcaaaat cagacttatc gggtaattga
     9001 gaatggagtt gaagtaacat tttgaagcct tgatatggtg gataaaatag ggtttttatt
     9061 ttggaaaacg tttcctttgt tttcaaattg ctaaaaaagt ggtacaatat aggatagctt
     9121 actattatct gaatcagctg atttggagag aaaggattca ttttgaaatc aataggcttt
     9181 attgaaaagc tgaaggggtt gtctagtaaa gagctgattt tattgggaat tatcctaagt
     9241 atctttttac ccttttatct ttttgtagtt gtactctgtt tatatattat cagtttgatt
     9301 tttacaggag acatgaaaag tattcttcag aaaatggggg agcatccgat gctgcttctt
     9361 tttcttagct atagtactgt tatatccatt cttgcacaaa attggatggg tcttgtggct
     9421 tcagtaggaa tgtttctatt tactattttc tttttgcact atcagtcgat tttatcccat
     9481 aaattctttc gattgatttt gcagttcgtc ttgtttggta gtgtcttgtc agctgctttt
     9541 gccagtttag aacatttcca aattgtgaag aaatttaact atgcttttct ttcacccaat
     9601 atgcaggtgt ggcatcagaa ccgggcagaa gtgactttct ttaatcctaa ttattatgga
     9661 attatttgtt gtttctgtat tatgattgct ttctatctgt ttacaacgac caagttgaat
     9721 tggttgaaag tattctgtgt gattgcaggc tttgttaatc tctttggttt gaactttact
     9781 caaaatcgaa ctgcctttcc tgctattatc gctggagcaa ttatctatct ctttacgact
     9841 attaaaaact ggaaggcctt ttggcttagt attggggtct tcgcgattgg tttgagtttc
     9901 ctcttttcta gtgatttggg agttcgaatg ggtactttag actcttctat ggaagaacgc
     9961 atttctatct gggatgctgg gatggccttg tttaagcaaa atcctttttg gggtgaaggg
    10021 ccattgacct atatgcactc ttatcctcgg atacatgctc cttatcatga acatgcccac
    10081 agtctttata ttgatacgat tctgagttac ggaattgtgg gtaccatttt attagttttg
    10141 tcttctgttg ctcctgttcg cttgatgatg gatatgagtc aggagtcggg gaaacgtccg
    10201 attatcggcc tttatctatc tttccttaca gtggttgctg tgcacggaat ttttgacttg
    10261 gctctcttct ggattcagtc aggctttatt ttcttgctag ttatgtgcag tattccattg
    10321 gagcatcgaa tgttggtatc ggacatgacg gattaagttt tataagtttg aaatcttcta
    10381 ccttgggtag gagatttttt tatacgatgg gcatgtcgtg catctgaggt gtaagtcctc
    10441 tgtagggatc cactaccggt gaatacaata gcgctcccca agcctgacta tcgtgaggta
    10501 gcggattaaa atggtctggg gatagatcgt tttaagtctg acgcaggaaa taagaattgt
    10561 cagagaaagc aatagtgaaa tcgtaggcta tgaatagaaa cgtgatagcg aggagcatat
    10621 agtggataag gtagcgagaa attttaaagt ataaaagata gtcttaatct atatatgtaa
    10681 atcacaaaag taattgaatt cggaataagg ttggtgtgaa aagacatagt aaactgaatc
    10741 ttgaatacta gaatgatact tctacaatat tgttataatt taatttgaat tccaaaatca
    10801 cattgttccg tccgtatttc attttactgt atgtcttcct aaactccaaa gtttctgcgt
    10861 caaatttcct attttcactg tagtctttga cacttcgaac gacaatttga atcatatatt
    10921 caaaaaaaaa tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt tgtttgattt
    10981 ttaatggata atgtgatata atggttgtca atctataatt cacataaaca gaggagtaga
    11041 aaatgaaaaa aaatcgtgta tttgctacag caggtcttgt tttattagca gcaggtgtac
    11101 ttgcagcatg cagttcttca aaatcatctg attcatcagc ccctaaagct tatggctatg
    11161 tttatacagc agacccagaa accttggact acctgatttc aagtaaaaat agtacaacag
    11221 tagtgacttc aaatgggatt gatggtttat tcactaacga taattacggt aatcttgctc
    11281 ctgcagttgc agaggattgg gaagtctcta aggatggttt gacctacact tataagattc
    11341 gtaaaggggt taaatggttt acctctgatg gagaagaata tgcagaggtg acggctaaag
    11401 atttcgtgaa cggtttaaaa cacgcagcag ataaaaaatc agaagctatg tatttagctg
    11461 aaaattcggt taaaggcttg gcagattatc tatcaggaac ttcaacagat ttttcaacag
    11521 ttggtgtcaa ggcggttgat gattatacgt tacaatacac tttgaaccag cctgaaccgt
    11581 tctggaactc taagttgacc tattctattt tctggcctct gaatgaagaa ttcgaaacat
    11641 caaaaggaag cgattttgct aaaccaacag atccgacatc cttgctttat aatggtccat
    11701 tcttgttgaa agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat gagcaatatt
    11761 gggataaaga aaatgtccac ctagatacta tcaatctagc ttactatgat ggatcagatc
    11821 aggagtcgct agagcgtaac ttcactagtg gagcttatag ttatgcccgt ctttacccta
    11881 ccagctccaa ctattctaag gttgcagaag aatacaagga caatatctat tacacacaat
    11941 caggctctgg gattgctggt ctgggtgtga atattgatcg ccaaagttac aactatactt
    12001 ctaaaactac agattcagag aaagtagcta ctaagaaggc attgcttaac aaagatttcc
    12061 gtcaagcctt gaattttgct cttgatcgct cagcttactc agctcaaatc aatggtaaag
    12121 atggagcagc tttagcagtt cgtaatttat ttgtaaaacc agactttgtt tcagctggtg
    12181 agaagacctt tggtgattta gtcgctgctc aacttcctgc ttatggtgat gagtggaaag
    12241 gtgtgaattt agctgatggg caggatggtt tattcaatgc tgacaaggcc aaggcagagt
    12301 ttgcgaaagc taagaaagct ttagaagcag acggcgttca gtttcctatt catctggacg
    12361 ttccagtaga ccaagcatca aaaaactaca tatctcgtat tcagtccttt aaacaatctg
    12421 tagaaacagt tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg acaagtgatg
    12481 aattccttaa tattacttac tatgctgcca atgcttcatc tgaggattgg gatgtatcag
    12541 gaggagtttc atgggggcca gactatcaag acccatctac ttacctggat attttaaaaa
    12601 caactagcag tgaaactaca aaaacatatt taggatttga taatccaaat agcccttcag
    12661 tagttcaagt tggtttgaaa gaatacgata aattagttga tgaagctgcc aaagagacaa
    12721 gcgacttgaa tgtccgttat gaaaaatatg cagcggctca agcatggttg acagatagtt
    12781 cactctttat tcctgctatg gcttcttctg gtgcagcacc agtgctttca cgaattgttc
    12841 catttactgg agcttctgcg caaacaggct ctaaggggtc agatgtttac ttcaaatatt
    12901 tgaaattaca agataaagtg gtgactaagg aagagtatga aaaagctcgt gaaaaatggt
    12961 tgaaagaaaa agctgaatca aatgagaaag ctcaaaaaga attggcaagt catgtgaagt
    13021 aaataatttc taatagaact ttctctccat gaggagaagg ttcttttggg atttttaaag
    13081 gaaataatat gaaaaaatat atttttatgc gtgttttgcg gtcattggtt tcgattttct
    13141 tagtaacgac tttgacctac acgattatct ataccttggt tcctcgaaaa ttgattttca
    13201 agcaggatcc taactataat aaaattgcga caacggctga taaacgtgat aactatgaaa
    13261 atactgtgtt tgagcgtatg ggctacattg agtattacga tactaaagag ttgcaagaaa
    13321 aggcaagtag catggattct tctgtaacag tagaagcaaa tgcgaccaat aaagctattt
    13381 atgaaaagta catcaatcaa ttaggtcatg gttggacttt gggagaattt actgaaagtg
    13441 gtcaattcta tgctactcgt gaaattccaa tttttgaacg tgtttttcac ttctatgcta
    13501 acttgattga cattgaccat acaaataaaa tccaagaccc tgaaaatcca gacttgaaac
    13561 gctaccttcg ttttgaaaat gatccagcta tcggatggtc attggtcggt tcaggaacta
    13621 aacataaata tctcttgtac tttaacagtc agttcccatt tgttcatcaa aactttgtga
    13681 acttgaattt aggtgactct tacccaacct atgctaatac accagttctt caggttatta
    13741 ctcaaggtca aggacaaacc aaaactgccc aagttcagtt cccaacaggt aagaaaacgt
    13801 cttctgtaaa tatttactca agaacctaca agtcacctag tcaggctgac tctcgtgaag
    13861 tagctagcta tgggaaagat gatccttata cagcgactga aagtaattac caatatccat
    13921 ctatgattgt cagctctgct attactggtt tgattggttt ggttcttgcc tatgctcttg
    13981 ccgtgccact tggttcagcc atggctcgtt tcaagaacac ttggattgat agcctctcaa
    14041 cagggacttt gaccttcttg cttgctcttc caacgattgc cttggtttac atcgttcgat
    14101 tgattggatc atctattgcc cttccagatt cattccctat cttgggagct ggagattggc
    14161 gttcttacgt tttaccagca gtcatccttg gtttattggg tgctcctgtt acagccattt
    14221 ggattcgtcg ttacatgatt gacttgcaat ctcaagactt tgttcgtttc gctcgtgcaa
    14281 aaggtttgtc tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc atggttccgc
    14341 tggtttcagg aattcctggt gccattattg gggttatcgg tggtgcaacc cttactgaaa
    14401 cagtcttcgc cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa gcatctaata
    14461 actctatggt cgttggtctt gtcttcatct ttacatgtat ttctatcttc tcacgtcttt
    14521 tgggagatat ttggatgact attattgacc cacgtattaa attgactgag aaaggaggca
    14581 aataatgtct acaatcgata aagaaaaatt tcagtttgta aaacgtgacg attttgcctc
    14641 tgaaactatt gatgcgccag catattctta ctggaaatca gtgtttaaac aatttatgaa
    14701 gaaaaaatca actgtagtca tgttgggaat cttggtagcc atcattttga taagtttcat
    14761 ctacccaatg ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg actttagtgt
    14821 tcgttatatc aagccaaatg cggagcattg gttcggtact gacagtaacg gtaaatcgct
    14881 ctttgacggt gtctggttcg gagctcgtaa ctccatcctc atttctgtga ttgcgacagt
    14941 gattaacttg gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa aatcagttga
    15001 ccgtgtcatg atggaagttt acaacgtcat ctcaaacatc ccacctcttt tgattgttat
    15061 tgtcttgact tactcaatcg gagctggatt ctggaatctg atttttgcca tgagcgtaac
    15121 aacatggatt ggtattgcct tcatgattcg tgtgcaaatc ttgcgctatc gtgacttgga
    15181 atacaacttg gcgtcacgta ctttgggaac accaaccttg aagattgttg ccaaaaatat
    15241 catgcctcaa ttggtatctg ttattgtgac aaccatgact caaatgcttc caagctttat
    15301 ctcatacgaa gccttcttgt ctttcttcgg tcttggatta ccgattacag tgccaagttt
    15361 gggtcgtttg atttcggatt attcacaaaa cgtaacaacc aatgcttact tgttctggat
    15421 tccattgaca acccttgtct tggtatcctt gtcccttttc gtagttggtc aaaacttagc
    15481 ggatgctagt gatccacgta cacatagata ggagtagaaa tgacaaaaga aaaaaatgta
    15541 attttgactg ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt attgacagcc
    15601 attcgcggcg tttcccttga actagtcgaa ggagaagtat tagccttggt aggtgagtca
    15661 ggatcaggta aatctgtttt gacaaagacc ttcacaggta tgctcgaaga aaatggtcgt
    15721 attgcccaag gtagtattga ctaccgtggt caggacttga cagctttatc ttctcacaag
    15781 gattgggaac aaattcgtgg tgctaagatt gcgactatct tccaggaccc aatgactagt
    15841 ttggacccca ttaaaacaat tggtagtcag attacagaag ttattgtaaa acaccaagga
    15901 aaaacagcta aagaagcgaa agaattggcc attgactaca tgaataaggt tggcattcca
    15961 gacgcagata gacgttttaa tgaataccca ttccaatatt ctggaggaat gcgtcaacgt
    16021 atcgttattg cgattgccct tgcctgccga cctgatgtct tgatctgtga tgagccaaca
    16081 actgccttgg atgtaactat tcaagctcag attattgatt tgctaaaatc tttacaaaac
    16141 gagtatcatt tcacaacaat ctttattacc cacgaccttg gtgtggtggc aagtattgcg
    16201 gataaggtag cggttatgta tgcaggagaa atcgttgagt atggaacggt tgaggaagtc
    16261 ttctatgacc ctcgccatcc atatacatgg agtctcttgt ctagcttgcc tcagcttgct
    16321 gatgataaag gggatcttta ctcaatccca ggaacacctc cgtcacttta tactgacctg
    16381 aaaggggatg cttttgcctt gcgttctgac tacgcaatgc agattgactt cgaacaaaaa
    16441 gctcctcaat tctcagtatc agagacacat tgggctaaaa cttggcttct tcatgaggat
    16501 gctccaaaag tagaaaaacc agctgtgatt gcaaatctcc atgataagat tcgtgaaaaa
    16561 atgggatttg cccatctggc tgactaggag gaaggaaatg tctgaaaaat tagtagaaat
    16621 caaagattta gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg ttaaaaatgc
    16681 taacttcttt atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg gtagtgggaa
    16741 aacaactatt ggtcgtgcta tcatcggtct aaatgataca agtaatggag atatcatttt
    16801 tgatggtcaa aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat tgattcgtcg
    16861 aatccagatg attttccaag accctgccgc aagtttgaat gaacgtgcga ctgttgatta
    16921 tattatttct gaaggtcttt acaatcaccg tttatttaag gatgaagaag aacgtaaaga
    16981 gaaagttcaa aatattatcc gtgaagtagg tcttcttgct gagcacttga ctcgttaccc
    17041 tcatgaattc tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct tggtcatgca
    17101 accagacttt gttattgcag atgagccaat ttcagccttg gacgtttctg tacgtgccca
    17161 agtcttgaac ttgctcaaaa aattccaaaa agagctcggc ctgacctatc tcttcatcgc
    17221 ccatgacttg tcggttgttc gctttatttc agatcgtatc gcagttattt acaagggtgt
    17281 tattgtagag gttgcagaaa cagaagaatt gtttaacaat ccaattcacc catatactca
    17341 agccttgctt tcagcggtac caatcccaga tccaatcttg gaacgtaaga aggtcttgaa
    17401 ggtttacgac ccaagtcaac acgactatga gactgataag ccgtctatgg tagaaatccg
    17461 tccaggtcac tatgtttggg cgaaccaaac cgaattggca cgttatcaaa aaggactaaa
    17521 ctagtaatgg ttttataatt tccatgtcaa tttttatgga aattaggctc tttgtcaact
    17581 gtagtgggtt gaagtcagct aagctcgaga aaggacaaat ttcgtccttt cttttttgat
    17641 gttcaaagcg ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac caaaagcatt
    17701 gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag aatagtgtag
    17761 ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga cagtctgaaa
    17821 aataggatga acctgcttaa gattgtcctc gataagttcg aaaaatttct ctggttcctt
    17881 attctggaag tgaaaaagca agagctgata gagctgatag tggtgtttca agtcttccga
    17941 ataactcaaa agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg
    18001 ataaaattgc ttatcactca gtttacggct atcctgttgt atgagcttcc agtagtgctt
    18061 gatagccttg tgttcatggg attttcgatg aaactgattc atgatttgga cacgcacacg
    18121 actcatagca cggctaagat gttgtacaat gtgaaagcga tcaagaacga ttttagcatt
    18181 cgggagtgaa acagtct
//
LOCUS       DAVKUR010000040        17598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKUR010000040 DAVKUR010000000
VERSION     DAVKUR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.040"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(162..365)
                     /locus_tag="VW749_001529"
     CDS             complement(162..365)
                     /locus_tag="VW749_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175549.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(358..1440)
                     /locus_tag="VW749_001530"
     CDS             complement(358..1440)
                     /locus_tag="VW749_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0175550.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1566..2348)
                     /locus_tag="VW749_001531"
     CDS             complement(1566..2348)
                     /locus_tag="VW749_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0175551.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2348..3691)
                     /locus_tag="VW749_001532"
     CDS             complement(2348..3691)
                     /locus_tag="VW749_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0175552.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3803..5119)
                     /locus_tag="VW749_001533"
     CDS             complement(3803..5119)
                     /locus_tag="VW749_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0175553.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5313..6539
                     /locus_tag="VW749_001534"
     CDS             5313..6539
                     /locus_tag="VW749_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0175554.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6738..8312
                     /locus_tag="VW749_001535"
     CDS             6738..8312
                     /locus_tag="VW749_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0175555.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8576..9364
                     /gene="codY"
                     /locus_tag="VW749_001536"
     CDS             8576..9364
                     /gene="codY"
                     /locus_tag="VW749_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0175556.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9364..9939
                     /locus_tag="VW749_001537"
     CDS             9364..9939
                     /locus_tag="VW749_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0175557.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFSPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10021..10106
                     /locus_tag="VW749_001538"
     tRNA            10021..10106
                     /locus_tag="VW749_001538"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10055..10057,aa:Leu,seq:aag)
     gene            10389..11519
                     /gene="ugpC"
                     /locus_tag="VW749_001539"
     CDS             10389..11519
                     /gene="ugpC"
                     /locus_tag="VW749_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0175558.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11666..11812)
                     /locus_tag="VW749_001540"
     CDS             complement(11666..11812)
                     /locus_tag="VW749_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175559.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12020..12778
                     /locus_tag="VW749_001541"
     CDS             12020..12778
                     /locus_tag="VW749_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0175560.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12865..13377
                     /locus_tag="VW749_001542"
     CDS             12865..13377
                     /locus_tag="VW749_001542"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0175561.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13559..14503
                     /locus_tag="VW749_001543"
     CDS             13559..14503
                     /locus_tag="VW749_001543"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0175562.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14512..15189
                     /locus_tag="VW749_001544"
     CDS             14512..15189
                     /locus_tag="VW749_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0175563.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLIKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15287..16045
                     /locus_tag="VW749_001545"
     CDS             15287..16045
                     /locus_tag="VW749_001545"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0175564.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16083..17588
                     /gene="lytC"
                     /locus_tag="VW749_001546"
     CDS             16083..17588
                     /gene="lytC"
                     /locus_tag="VW749_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0175565.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5282 a         3172 c         3922 g         5222 t
ORIGIN      
        1 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggggc
       61 agttcattct acacccacta ttatgcgttt tattgtggga agattttcct cattttctag
      121 tgaaattgaa ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc
      181 attgttgttt cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta
      241 tcattccaga cacttagggt tagattattg cagccaattt ctttagcata atagcagaaa
      301 aatgacaata aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta
      361 atcaaaataa agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac
      421 aacaccgcag tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac
      481 agagaagcac atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc
      541 atggacatcc ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc
      601 tttttcgatg atctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat
      661 aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg
      721 gtctggtttg ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac
      781 ccccaggtca aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg
      841 tggattcgca gcattatcac cagtcaagac catggtatca aagctcattt cgtaaccttc
      901 acgtttcatg gcaaagtcaa tttgtgcgat gatatctgtc tcagtcttat caagagaaat
      961 attgtcaaaa ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg
     1021 tacttcatca gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttttcaaa
     1081 ctcagcagtt tcaaaaattg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa
     1141 ctcaacagcg acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg
     1201 attttcagaa tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac
     1261 ttcaagagct gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg
     1321 gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac
     1381 gacagcgacg tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat
     1441 atgctacctt ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa
     1501 gggtaaaaga aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc
     1561 tttgtttaag aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg
     1621 ctgaggatat cctcataggc agggagttgg atatcctgac catatttctt cttgagggca
     1681 gtagtaacta ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag
     1741 gaaccaaaga cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt
     1801 ccatagacaa cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga
     1861 ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata
     1921 aaacggttat tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt
     1981 tttcctgaag cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga
     2041 actacaccgt cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct
     2101 gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt
     2161 tcatcaaagt catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca
     2221 gccacatact tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg
     2281 tagaggtggg caatgttgag ctgatagggg taattgccat cttttgagga aagtgaagta
     2341 taaaccatta gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt
     2401 ccagcatggc agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg
     2461 tcttgagaac ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca
     2521 ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt
     2581 ccatgtcagt gatttgttca aagtctgcat cccagatcca gctagtgtca attccatctg
     2641 catagttggc attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt
     2701 cgatagcttg ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac
     2761 cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga
     2821 tgagttgcga atcggcacct aggaaacggg cgatggccac agcagctagg gcgttataga
     2881 tattatagag cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc
     2941 gattgttggt caactcaacc agttttgtca aacgatagtc gagatcagga cgtttacatc
     3001 cacaaccttc acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga
     3061 tgccttggca gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc
     3121 ccttttccaa gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa
     3181 gtggactgtc tccgttaagg agaacagtag cagttggaac tttccgaatg gcatccaata
     3241 tcatgttata ggtagtatag atttcaccga aacggtccat ctggtcacgg aagatattag
     3301 taatgacaaa aagactaggc tggatatagt cacagatacg agatagactg gcttcgtcaa
     3361 tttcgaggac ggcaatattt ttcccagttt tagaagattt ggctgttagg aaggttgttg
     3421 caatccctgt aatcatgttg gcaccgcttg ggttggttag aacttgacca taaacctctt
     3481 ttaaaatgcc gacagtgagg gcagttgtca gggtttttcc atttgttcca gtgacaacga
     3541 caatctcgta gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt
     3601 tccctgggag cgtacttcca cgtccaagac ggcttaaaac gaagtgggaa gaacgcccag
     3661 caagaaggcc caaagtagtt tttaagttca tgtttctatt atatcacaaa agtatatcac
     3721 aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca aagagggctg
     3781 tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc tcagccaagg
     3841 ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg tccatagcaa
     3901 cagtaataat gttgatgatt tcttgagaac cttctgagaa gatgcttgca ccaagaattt
     3961 cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca tttacgtgac
     4021 cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc aaatcagctg
     4081 cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata gtatttggca
     4141 cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg taaacaacac
     4201 ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct ccaactgcaa
     4261 agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca cgttcagtta
     4321 gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt ccagttgcgt
     4381 agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact tggtcaccgt
     4441 cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct tcttccatgt
     4501 attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta tccaaggcat
     4561 ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca agaccgatat
     4621 ttccgccacc aaggactcca agtttttcag gcaatttatc caagctttgg atacctgttg
     4681 agtcaaagac gtttttgctt gtagcaagtc cagggattgg caagacgttt gaaacagcac
     4741 cagtgttgat gacgatagtt tcagcagtca attcttgttt ttcatcacca gcttggattt
     4801 cgatgacttt atttgaaagg aagtgagctt cagcatcaaa gatatcgacg ccagtaccag
     4861 caacagtcgt atagttttta ccgttgaggc gaccagtgat cgtgtttttg gtagcaatga
     4921 cttcttcaaa agacaagtct ttctcagcag caaccagcaa agttttagtt gggatacaac
     4981 cgatgttgat acaagttcca ccgtacatag ctttgctacg ttcaacgagg gcaacttttt
     5041 tgccagctga agccaattta ccagctagtg ttttaccagc tttaccaaat ccgataacga
     5101 ttaaatcata agttaacatt tagaattcct cctattcgaa ttacattcta gcacaagaaa
     5161 aaaacttttg cacaattctg ctacgaaaaa gacagaaaaa tatgaaaacg cttttcaggc
     5221 aaaaaactag taattttttg acaagcttga taaactaaaa tcctatctat ttttatataa
     5281 gatagaataa atgttcgaaa ataggaggtt ttatgaaatc gaatcgttat attattgcct
     5341 ttgctggggt cattttacac ttaatgctgg gttcgactta tgcctggagt gtttatcgta
     5401 accctattat tgaaaaaacg ggatgggatc aggcttctgt tgccttcgcc tttagtctag
     5461 caatcttttg tttgggctta tcggctgcat ttatggggcg tttggtagaa aaatttggtc
     5521 cgagagtcat ggggagtcta tctgcttttc tatacgcagg tggaaatatc ttaacaggat
     5581 ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc ttatggcatt ttaggtgggc
     5641 ttggtttggg agcaggctat attacccctg tgtcaacgat tataaaatgg tttcctgata
     5701 aacgtggtct cgcaacaggt ttagcgatta tggggtttgg ttttgcttct ttattgacta
     5761 gtcccatagc gcaacatctc atcgcagggg tagggcttgt agaaactttt tatattttag
     5821 gtgcaagtta ctttattatc atgctcctag cttcacaatt cattaagcgt ccaaatgagc
     5881 aagagcttgc aattttatct gcttcaggga aagaaaaaac agactctctg acgcaaggga
     5941 tgactgcaaa tcaggctcta aaaagcaatc ggttttatat gctttggatt attttcttta
     6001 tcaacatagc ttgtggttta ggcttaattt cagcggcatc gccaatggca caggagatgg
     6061 ctggcttgtc tacaagtcat gcagcagtaa tggtgggtat tttggggatt ttcaatggat
     6121 ttggtcgctt gctctgggcg agtttgtctg actatatcgg tcgccctcta acctttagta
     6181 tattactgct tgtcaatctt ttcttttctc tctcactttg gctctttaca gattccgttt
     6241 tatttgtagt tgctatgtct attttgatga cttgctatgg agctggtttt tctttgattc
     6301 cagcttatct cagtgatatt tttggaacca aggaattggc cgctctgcat ggttatattt
     6361 taacagcttg ggcaatggct ggtttagcgg gacctatttt attagcagag acttataaaa
     6421 tggctcattc gtacacacaa accttgttcg tttttctcat tttatacagt atcgccttgg
     6481 ctttgtctta ttatctaggt cgttcaatca aaaaagaaag tcaaaaaccg cttacatgat
     6541 tttctgtaga aatggggcta tcttttgctc tggtcttgtg ttatactaga taggttgcaa
     6601 agaaaacagt acttttcttt tgtggaaaag aagcaacacg attttatatc tagttatatg
     6661 aaaatacgtc ataaaaagaa aagtataaac taagccctat agggtggctt cgcaccacct
     6721 ttagaaagaa gaataacgtg aaatttaatg aattaaactt gtctgctgat ttgctagcag
     6781 aaattgaaaa agctggtttt gtagaagcta gtcctatcca agaacaaact attcctttgg
     6841 cccttgaagg caaggatgtt atcggtcaag ctcagactgg tacaggaaaa actgcagcct
     6901 ttggcttgcc tacccttgaa aaaatccgta cagaagaagc gactatccaa gctttggtca
     6961 tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga actcttccgc tttggtcgta
     7021 gtaagggagt caaagtccgt tcagtatatg gcggatcaag cattgaaaaa caaattaagg
     7081 ctcttaaatc tggtgcccat atcgtggtgg gaactccagg tcgcctcttg gacttgatta
     7141 aacgcaaggc cttgaaatta caagacattg aaacccttat ccttgacgaa gcggatgaaa
     7201 tgcttaacat gggcttcctt gaagacatcg aagccattat ttcccgtgta cctgagaacc
     7261 gtcaaacttt gcttttctca gcaactatgc cagatgccat caaacgtatc ggtgttcagt
     7321 ttatgaaagc ccctgaacat gtcaagattg cggctaagga attgacaaca gaattggttg
     7381 accagtacta tatccgtgtt aaggaacaag aaaaatttga caccatgact cgtctcatgg
     7441 atgtggcaca accagaactc gctattgtat ttggtcgtac caaacgccgt gtggatgaat
     7501 tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg aattcatggc gacctagacc
     7561 aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg caatcttgat gttttggttg
     7621 cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt gacccatgtc tacaactacg
     7681 atattccaca agatcctgag agttatgttc accgtatcgg tcgtacaggt cgtgctggta
     7741 agtcaggtca atctattact tttgttgctc caaacgaaat gggttacctt caaatcattg
     7801 aaaacttgac taagaaacgc atgaaaggtc tcaaacctgc aagtgtagaa gaatccttcc
     7861 aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga ttttgcagat gaaaccattc
     7921 gtgccaactt tgagaaattt ggtaaggatg ctcgcaaatt ggctgctgag tttactccag
     7981 aagaattggc aatgtatatc ttgagtctga cagtccaaga cccagatagc cttccagaag
     8041 tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc aggtaatggt ttcggtggta
     8101 aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg tcgagagcgt gatcgccgtg
     8161 gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg caacgatcgt tttgataagg
     8221 aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac tttaagcgaa aagcaaacag
     8281 gctttgttat tcgtaacaag ggcgataaat aagaaaaagc ggttcaaaat gaatcgcttt
     8341 tttatataag gagaccgaat gtgaaaagac aaataaaatt attatattat cttttataat
     8401 gttatgatac acaaaaatag gcaacttgtc aatagaaaag gaacaattta attaaaaata
     8461 ttctggtttt taattaaatt gtaagtcaat gcaagtcaat aaggaatttt cagataatta
     8521 ttgaaaaaga gacgttttta tgttataatg atagcgatta aattcgaggt gaaaaatggc
     8581 acatttatta gaaaaaacta gaaaaattac atcaattttg aaacgctcag aggagcagtt
     8641 gcaggatgag cttccttaca acgctattac gcgtcagtta gcggatatta ttcattgcaa
     8701 tgcctgcatt atcaatagta agggacgtct gcttggctat tttatgcgtt ataaaacaaa
     8761 tacagatcgc gtagagcaat tcttccaaac taagattttc ccagatgact acgttcaagg
     8821 ggctaatatg atttacgaaa cagaagcaaa cttgcctgtt gagcatgata tgagtatttt
     8881 ccctgttgag agtagagatg attttccaga tggcttgacg actattgcac cgattcatgt
     8941 atcggggatt cgccttggtt ctttgattat ttggcgtaat gataaaaaat tcgaagatga
     9001 ggacttggtt cttgttgaga ttgccagtac cgttgttggg attcagcttc ttaacttcca
     9061 acgtgaagaa gatgagaaaa atattcgtcg tcgtactgct gtcaccatgg cggtcaatac
     9121 cctttcttac tccgaactcc gtgctgtttc agcaatttta ggggaattaa atggaaatga
     9181 agggaagttg actgcgtcag tgattgcaga tcgtatcgga atcactcgct ctgtgattgt
     9241 caatgctctt cgtaaacttg agtctgcggg gattattgaa agtcgctcac ttggaatgaa
     9301 gggaacctat cttaaggtct tgatttcaga tatttttgaa gaagtgaaga aaagagatta
     9361 ctaatgacaa aggctttaat ttcgattgat tatacagaag attttgttgc tgatagtggg
     9421 aaactaacag caggtgctcc agctcaggcg atttcggatg ccatcagcaa ggtaactcga
     9481 ttagcttttg aacgaggaga ttatatcttc tttactattg atgctcatga agaaaacgat
     9541 tgtttccatc cggaaagtaa gttattttct cctcataatc tgattgggac gagtggacgg
     9601 aatttatatg gagatttggg gatcttttat caagagcatg gttcagacag tcgtgtcttt
     9661 tggatggata aacgccatta ctcagctttt tcagggactg acctagatat tcgtttgaga
     9721 gagcgtagag tgtctaccgt tatcttaaca ggtgtcttga cggatatctg tgtcctacat
     9781 acagctatag atgcctataa tctaggatat gacatcgaga ttgttaaacc agctgttgct
     9841 tccatctggc ctgaaaatca tcaatttgcc ctaggtcatt tcaaaaatac actcggagct
     9901 aagttagtag atgaaaatct aaatgaactt tctgagtaac ctggttggtg aaaatgaaaa
     9961 aatttgaaaa aaagtgttga caagcatccc aaaagttgat atactagtaa agtaatcgat
    10021 gcggggatgg cggaattggc agacgcgcag gactaaggat cctgtgaccg ctttaggtcg
    10081 tgagggttca agtccctctc tccgcatagg aaaagagtta gctaaagcta gctcttttgt
    10141 atttctctaa aaaattagaa tccagtcaaa tgtagtggag aatcagcgaa aatatgggaa
    10201 aactgatcct tgtttctgct tttgtcatag aagaataata aagattatct tcttcaaatt
    10261 ctccgatatt ctctaaagtt ttgtgcaagt tgcacagaac ttttttattt ttttggtcat
    10321 cttgccatag aaatataaag cgttttcatc tataatataa ttatcaaaag acaaaaggag
    10381 ttcacctcat ggtagaattg aatcttaaaa atatttacaa aaaatatcca aacagcgaac
    10441 actattcagt tgaagatttc aacttgaaca tcaaagataa agaatttatc gttttcgtag
    10501 gaccttcagg atgtggtaaa tcaactacac tccgtatgat tgctggtctt gaagacatta
    10561 cagaaggtac tgcatctatc gatggcgtgg ttgtcaacga cgtagctcca aaagaccgtg
    10621 atatcgccat ggtattccaa aactacgctc tttacccaca catgactgtt tatgacaaca
    10681 tggctttcgg tttgaaattg cgtaaataca gcaaagaaga cattaacaaa cgtgttcaag
    10741 aagcagctga aatacttgga ttgaaagaat tcttggaacg taaaccagct gacctttcag
    10801 gtggtcaacg tcaacgtgtt gccatggggc gtgcgattgt ccgtgatgcg aaagtattct
    10861 tgatggacga acctttgtca aacttggatg ccaaacttcg tgtatcaatg cgtgctgaaa
    10921 tcgctaaaat tcaccgtcgt atcggagcta caactatcta tgtaactcac gaccaaacag
    10981 aagcgatgac acttgcagac cgtatcgtta ttatgtcagc tactaagaac cctgctggta
    11041 caggtactat cggacgtgta gaacaaatcg gtactcctca agaagtttac aaaaatccag
    11101 ttaacaaatt cgttgcagga ttcatcggaa gcccagctat gaacttcatc accgtgaaat
    11161 tggttggtag cgaaattgtt tctgacggtt tccgtttgaa agtgccagaa ggagcattga
    11221 aagttcttcg tgaaaaaggc tacgaaggaa aagaattgat ctttggtatc cgtccagaag
    11281 acgtgaatgc agaacctgct ttccttgaaa cattcccaga ctgtgttgta aaagcgacta
    11341 tctctgtatc agaactgctt ggttcagaat ctcaccttta ctgccaagtt ggtaaagacg
    11401 agtttgttgc aaaagttgat gctcgtgact acttgcaaac aggtgcaaca gttgagcttg
    11461 gatttgactt gaacaaagca cacttcttcg atgtagaaac tgaaaaaaca atctactaaa
    11521 ataaataaaa ttcaaagcac tacaagaaaa gatatctctt tatcaattgt agtggagaga
    11581 tatcagttaa tctagggaga gaaacaaaat gcttctctcc tttttgctag ggaagtcata
    11641 ttatgcatct atattgtgat gctctttaat actcttcgaa aatctcttca aaccacgtca
    11701 acgtcgcctt gccgtacgta tgattactga tttcgtcagt tttatctgca acctcaaaga
    11761 tgtactttga gcagcttacg gctagtttcc tagtttgctc tttgatttcc attgagtatt
    11821 atttgtgggt accatctaca agtgaagcta tatgcgtaaa ctacgtgagc aattgaattc
    11881 gaactagaga ggtaataata aatttatgct atagttatgg tgacttgtat gcttttgatt
    11941 ctagtttatc aaataataga ttagaattgt cagataatat cattttgtgt tataatgaag
    12001 aaaaaacaga ggtgttcaaa tgtcagaagc aggtcataag tttttagcaa aattggggaa
    12061 aaaacgctta cgtccaggtg gaaagcgtgc cacagattgg ttaattgcag aaggaggatt
    12121 ttcaaaagaa aagagaatac tagaggttgc gtgtaatagg ggaactacag caattgagtt
    12181 ggcacagcgt tttggttgca agataactgc tgttgatatg gatgctcaag ctttagaagt
    12241 ggctaaaaaa tctgctggaa cggcaggtgt tgctcattta atcagttttg aaagagcaaa
    12301 tgcaatgaaa cttccttatc aagatgctag ttttgatatt gttataaatg aagctatgct
    12361 gactatgcaa gccgatcaag ctaagaaaaa atgtgtaatg gaatatctaa gggtattaaa
    12421 acctggaggt cttctcttga cacatgatgt gcttcttaag gaagctaaag agtctatcag
    12481 acaggaatta tcacaagcaa ttcatgtaaa tgtaggtcct ttaactcaag atggttggga
    12541 acaggtgatg atagaatcag gttattgtga tgtgaaagca ttgactggtg aaatgacatt
    12601 aatgaaatta tcgggtatga tttatgacga aggtttgcta ggaactttga aaatttgtgt
    12661 aaatgcttgt aaaaaggaga atagaaagca gtttttaact atgtataaaa tgtttgctaa
    12721 gaataaacag aaattgggct ttattgcgat ggctagttat aaatcgtcaa aacgttagat
    12781 aattattgaa gttaactttt ccttttttct ttcttaaaaa atatgctata atagagagta
    12841 aaaaactttg aaagaaagaa aaagatgaat ttaaaagatt acattgcaac aattgaaaat
    12901 tatccaaagg aaggcattac cttccgtgat attagtcctt tgatggctga tggaaatgct
    12961 tatagctacg ctgttcgtga aatcgttcag tatgctactg acaagaaagt cgacatgatc
    13021 gtgggacctg aagctcgtgg atttatcgtg ggttgtccag ttgcctttga gttgggaatt
    13081 ggttttgcgc ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc tgctgactat
    13141 gaaaaagagt acggtgtcga taccttgact atgcacgcgg atgccattaa gccaggtcaa
    13201 cgtgttctta ttgtagatga ccttttggcg acaggtggaa ctgttaaggc aactatcgag
    13261 atgattgaaa aacttggtgg tgttatggca ggttgtgcct tccttgttga attggatgaa
    13321 ttgaacggcc gtgaaaaaat tggtgactac gactacaaag ttcttatgca ttattaatga
    13381 aaacagtccc tagggctgtt ttctctacac taggatataa aaatagacta taactagtta
    13441 gagaaaaact ataattgaaa actatatctt cttgcagtat aataaaagga ctaagtgttt
    13501 gagatttgtc ttcaaacata tgcaattatt cctgaaagag tacagttagg agagggttat
    13561 gccgattcga attgataaaa aattgccagc tgttgagatt ttacggacag agaatatctt
    13621 tgtcatggat gatcaacgtg ctgcccacca agatatccgt cctttgaaga ttttaatttt
    13681 aaatctcatg ccacagaaaa tggtcacaga gacccagttg ttgcgccact tggctaatac
    13741 acccctacaa ctggatattg attttctcta tatggagagc caccgttcta aaacaactcg
    13801 ttcagagcac atggagacct tctataaaac ttttcctgaa gtcaaggatg agtattttga
    13861 tgggatgatc atcacgggtg ctccagttga gcatttacca tttgaggaag tggactattg
    13921 ggaggaattt agacagatgc ttgagtggtc taagactcat gtctattcga cccttcatat
    13981 ctgttggggg gctcaggctg ggctttatct gcgctatggt gtagaaaaat accagatgga
    14041 cagtaagcta tcaggtattt atcctcagga caccctaaaa gagggtcacc ttctatttag
    14101 aggctttgat gatagctatg tatcccctca ttcacggcac acggagattt ctaaggaaga
    14161 ggtcttaaac aagaccaatc tcgagatttt atcagaagga cctcaggttg gggtttctat
    14221 tttggccagt cgtgatttac gagaaattta tagttttggt catttggagt atgaccgtga
    14281 taccttggca aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac atattccaga
    14341 aaattacttt aaagatgatg atgttaatca ggtaccttgt ctttgttggt cttcatctgc
    14401 agccctcttt ttcagtaatt gggtaaacca tgcggtctat caggagacgc cttttgattg
    14461 gagaaagata gaagatgatg catctgcata tgggtattta taagaggaat tatgacatat
    14521 ttagacgctt ttaaatcagg taccttggtt ttaccgagtg ccctgctctt gcattttaag
    14581 gaactctttc cttctagcga cgattttctg gtttggcaat ttttctattt gcaaaatacg
    14641 acaggcttag aagaaatgtc gccaagccag attgctgaaa ggattggcaa ggaaatttcg
    14701 gatgtcaacc agtccatttc taatctgacg gaaaggggac tgctccagta tcgtactatc
    14761 gaattaaatg gcgaaattga attgctcttt gatgctagtt tggccttgga acgtttggat
    14821 gacctgtttg gagcagttcg ttcaagttca gaccagctaa cacctcaaaa ccagctcaag
    14881 gatttggtgg aaaccttcca gcaggagttg ggacgattgt tgacgccttt tgagattgag
    14941 gatttgatca agacactaaa ggaagatgga accagtgctg acttgattaa ggaggctctt
    15001 cgtgaagctg ttttgaatgg aaaaccaaac tggaagtaca ttcaggcgat tttgagaaac
    15061 tggcgccatg aaggaatcaa gagtgtggct caaattgagg ccaagagagc agaaagagaa
    15121 gcaagcaatc ctcagttgac acaggtatct gcagatttca gaaatgccat ggatctctgg
    15181 aaggattaat ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc tgtgtataat
    15241 tgtgatagaa taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc
    15301 atttatcgct ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga
    15361 agcagttgca tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc
    15421 tcttgatttg acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca
    15481 aaactgctac tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa
    15541 agaaatcggt actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga
    15601 aactgatgaa gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat
    15661 catctgttgt ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg
    15721 tgctcaagta tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat
    15781 cgcttatgag ccaatctggg ctatcggtac tggtaaatca gcttcacaag atgatgcaca
    15841 aaaaatgtgt aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga
    15901 caaagttcgt gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc
    15961 ttgcccagac gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt
    16021 ggctttgctt gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc
    16081 agatgtctgt tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa
    16141 gtatctgttt actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa
    16201 aaacttcgca ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata
    16261 aaacgcaaac gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt
    16321 atgtaaagga tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg
    16381 cttggtttta tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact
    16441 acctgaaatc aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga
    16501 gttggtttta tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa
    16561 ataagtggta ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt
    16621 atttcttgaa tggtcaagga gctatgatac aaaatgaatg gctctatgat ccagcctatt
    16681 ctgcttattt ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg
    16741 gcggcaaatg gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca
    16801 actactattt gactggaagt ggtgccatgg cgactgacga agtgattatg gatggtgctc
    16861 gctatatctt tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg
    16921 ttcacagaga tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac
    16981 atgctaagaa aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg
    17041 ttattgatga gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag
    17101 acaaggaatt ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct
    17161 atctctatac ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg
    17221 aacttataaa gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact
    17281 gggaatatgt aaataagagc aagagagctc caagtgatac agacacttgg gttaaaatca
    17341 tcaacaagta catggacacg atgaagcagg cgggttatca aaatgtatat gtctatagct
    17401 atcgtagttt attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg
    17461 tagcggccta tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt
    17521 ggcaatatac ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt
    17581 ggtattaagc gatgattt
//
LOCUS       DAVKUR010000041        17339 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKUR010000041 DAVKUR010000000
VERSION     DAVKUR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.041"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..697
                     /locus_tag="VW749_001547"
                     /pseudo
     CDS             1..697
                     /locus_tag="VW749_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(761..1843)
                     /locus_tag="VW749_001548"
     CDS             complement(761..1843)
                     /locus_tag="VW749_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0175566.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1840..2817)
                     /locus_tag="VW749_001549"
     CDS             complement(1840..2817)
                     /locus_tag="VW749_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0175567.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3032..3409
                     /locus_tag="VW749_001550"
     CDS             3032..3409
                     /locus_tag="VW749_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0175568.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            3644..5035
                     /locus_tag="VW749_001551"
     CDS             3644..5035
                     /locus_tag="VW749_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0175569.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5149..5991
                     /locus_tag="VW749_001552"
     CDS             5149..5991
                     /locus_tag="VW749_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0175570.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6264..7025
                     /locus_tag="VW749_001553"
     CDS             6264..7025
                     /locus_tag="VW749_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0175571.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7218..8135
                     /gene="glyQ"
                     /locus_tag="VW749_001554"
     CDS             7218..8135
                     /gene="glyQ"
                     /locus_tag="VW749_001554"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0175572.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8347..10383
                     /locus_tag="VW749_001555"
     CDS             8347..10383
                     /locus_tag="VW749_001555"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0175573.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10425..10682
                     /locus_tag="VW749_001556"
     CDS             10425..10682
                     /locus_tag="VW749_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0175574.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10905..12149)
                     /locus_tag="VW749_001557"
     CDS             complement(10905..12149)
                     /locus_tag="VW749_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0175575.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12168..12773)
                     /locus_tag="VW749_001558"
     CDS             complement(12168..12773)
                     /locus_tag="VW749_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0175576.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12833..13756)
                     /locus_tag="VW749_001559"
     CDS             complement(12833..13756)
                     /locus_tag="VW749_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0175577.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14050..15429
                     /locus_tag="VW749_001560"
     CDS             14050..15429
                     /locus_tag="VW749_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0175578.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15581..16456
                     /gene="pdxS"
                     /locus_tag="VW749_001561"
     CDS             15581..16456
                     /gene="pdxS"
                     /locus_tag="VW749_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0175579.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16457..17041
                     /gene="pdxT"
                     /locus_tag="VW749_001562"
     CDS             16457..17041
                     /gene="pdxT"
                     /locus_tag="VW749_001562"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0175580.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
BASE COUNT         5267 a         3171 c         3818 g         5083 t
ORIGIN      
        1 cgttcctaca cacgtgatgc cttctatcaa ctgttgaagc accatggttg gcgaaatatt
       61 atgccacgtc cagaacatcc taggaaagca gacgctcaaa ccattgtcgc gtctaaaaat
      121 aaaatctcaa ttcaagaaga caagaaagcg ctttaaaacc agtagacctt ttcataaggt
      181 tcgcttgatg taccaagatg aggctggttt cggtagaatc agtaaactgg gatcttgttg
      241 gtctccaata ggagtaggtc cacatgtcca tagtcactat atacgagaat ttcgctattg
      301 ttatggagct gttgatgccc catacaggcg aatcattttt cttaatagct ggtggatgta
      361 atactgagtg gatgaacgtc tttttagaag agctttcaca agcttatcca gatgattatt
      421 ttttactcgt tatggacaat gctatatggc ataaatcaag taccttaaag attccgacta
      481 atattgattt tacctttatt cctccataca caccagagat gaacccattg aacaagtgtg
      541 gaaagagatt cgtaaacgtg gatttaagaa taaagccttt cgaactttgg aagatgtcat
      601 gaatcaactc caagatgtca tacaaggact ggagaaggag gtgataaagt ccatcgttaa
      661 tcggagatgg aatagaatgc tttttgaaag cagatgagta taaaattgaa ttgcttataa
      721 aaaagctcca tacactggat gtgtatagag caatggggct ttatttgata tagagttctt
      781 ggttttttag gacaatttct cggatacttg caaacttttt aagttttttg atttcttctg
      841 gatgagtgac gagagtaata acatatcctt ccttgcccat acggccagta cggccagcac
      901 ggtgtgtgta ggtttcgcta tctctaggaa tatcaaagtt tacgacacat tctaggctat
      961 cgatatcaat tccacgagcc aaaaggtcag ttgcaagaag cagggttagt tggttatctt
     1021 taaacttttc taagatgatt tttctaaatt taacattaac atcactagcg agggaaacag
     1081 ccaatatatc acgatactgt agtttttcct cggcattccc aaggtctgac aggctattga
     1141 agaagactag accacggaaa tcctctacat gagccagttt tcgcagcata tccactcgat
     1201 gacgttggtc tacctgcatg tagaaatgct ggatattgtc caatttttga tcagagagat
     1261 caatagtgcg tgtattcggc acaatctttt cttggtcaaa cttggtcgtg gcactcatgt
     1321 agaccagttg gtggtcacga ggtgcgtagt gagtgatttt ttctacaaag tgaatctgag
     1381 aatcatctag taattggtca aattcatcca ggatgatggt ttccacattc atcatcttga
     1441 tttttttaag tttaatgagt tcaaagatac ggccaggagt tccaatcaga atttctggcc
     1501 cctttttaag acgttcaatt tgtcgtttct gacttgaacc tgaaaggaag agttgagcag
     1561 tcaatccgat agcttctgcc cacgttttac atacatcaaa aatctgtcca gcaagttccg
     1621 tatttggtgc tagaatcaag agttgttggg cttttttctt ttgtagtctg agaagacttg
     1681 gtaggagata cgctagggtc ttaccagttc cggtttggct cactcctagg aggttttctc
     1741 cagcaagaag gggctcaaat agttgagttt gaatgggggt gaattcttgg aaaccgagtt
     1801 ggtcactcag ttcttgccat tcagtcggta gtttggtttt catttttctg cctcaaatct
     1861 aatgccagca gtctggcgca tggtatatag tagctcatga acagagcctg catcatacag
     1921 ccaagtttgg tagagattca gatctggttg ctggatcatg tgtgcaaatg cagcgacttc
     1981 ctcagtcatc gtatgaggag cctgttggat aggaagctgg acttgatttc cttggtggtc
     2041 ggtaaaaata gctgagcgaa tatgctcaat cgtgttgaga gtcaaggttc catctgttgt
     2101 ataaatctcg caaggaagat tggaagtgat gttttttcca gccttgatgt gaacttgata
     2161 gtctgggtag aagaggatac catctccatt taggtcaatg ctattgtcaa gctgttgagc
     2221 atggtaagtc gcgtcattag ctttttcaaa aagacgaaca gcagcataga ggggataaat
     2281 ccccaaatcc atgagggctc caccagcaaa acggtctgaa aagacatttg gtgtttgtcc
     2341 agccaacaag tcaggcatct tggaagagta tttggcatag ttgaaatctg ctcctaacac
     2401 ttgcttatct gctaaaaagt ttttgatagt agtaaaggct ttctcgtggt aattacgagc
     2461 tgcttcaaag ataaaacagt tatttttttc agctgtttga atcaaatcaa accattcttg
     2521 tggttgagtg acagctggct tttcgagaat aacatgttta ccagcagaca aggcagcttt
     2581 tgcctgagca aaatgtaagg agtttggact ggcgatatag actaaatcaa aagaagattt
     2641 gaagaagact tctaattgat cgaatagttg gatattctga tagcgagaag caaaggttgc
     2701 tgcagtttct agttttctag aatagattgc gaccagttgg tattctccac tggtatgggc
     2761 tgcttctatg aaatgatggc tgatagcgcc agttccgatg acacctaatt ttagcataaa
     2821 tactcctttt ccgattttaa atccttcttt cattataaca tagatagacg ggactatcca
     2881 acagagagga gaaaatttca aataagctat tagctttctt ttccgaataa atagatagaa
     2941 gcatagaatc tagcaaacct agatttaaaa atgtgctata atagaaggag gaaaaggagg
     3001 attctcagac atccaggtat cagcccaact aatgatttgt caatttatcc gcgatatgct
     3061 ggacttgcca gcaaaaaatg tgacgatttt ggagggaagt aacattcacg tcttgccttc
     3121 catgccctac tcagcgcaag atttctatac tagtatagac gtcttggcgg agttagataa
     3181 tggaatccaa gttatcatcg aaattcaggt tcatcatcag aattttttca tcaatcgcct
     3241 atgggcttat ctgtgcagtc aggttaatca aaacctagaa aaaattcgcc aacgtgaagg
     3301 tgatacccac cagagctaca aacaaatcgc accagtatac gctatcgcaa ttgtcgatag
     3361 taattacttc tcagatgacc tagcttttca tagttttata gtaaaatgaa atgagaacag
     3421 gacaaatcga tcaggacaat caaatcgatt tctaacaatg ttttagaagt ataggtctac
     3481 tattctagct tcaatctact agaaattcca tagatataaa actacataat ctctacagat
     3541 acggatgttg gagttgatgt aagatgcttt ggcttgctag aggaattgtg gattgccaaa
     3601 ttgtatcatt gaaattattg ctcaaatttg ttatgatata aatatgaata aaagtagact
     3661 aggacgtggc agacacggga aaacgagaca tgtattattg gctttgattg gtattttagc
     3721 aatttctatt tgcctattag gcggatttat tgcttttaag atctaccagc aaaaaagttt
     3781 tgagcaaaag attgaatcgc tcaaaaaaga gaaagatgat caattgagtg agggaaatca
     3841 gaaggagcat tttcgtcagg ggcaagccga agtgattgcc tattatcctc tccaagggga
     3901 gaaagtgatt tcctctgtta gggagttgat aaatcaagat gttaaggaca agctagaaag
     3961 taaggacaat cttgttttct actatacaga gcaagaagag tcaggtttaa agggagtcgt
     4021 taatcgtaat gtgaccaaac aaatctatga tttagttgct tttaaggttg aagagactga
     4081 aaagaccagt ctaggaaagg ttcacttaac agaagatggc caacctttta cacttgacca
     4141 actgttttca gatgctagta aggctaagga acagctgata aaagagttga cctccttcat
     4201 agaggataaa aaaatagagc aagaccagag tgagcagatt gtaaaaaact tctctgacca
     4261 agacttgtct gcatggaatt ttgattacaa ggatagtcag attatccttt atccaagtcc
     4321 tgtggttgaa aatttagaag agatagcctt gccagtatct gctttctttg atgttatcca
     4381 atcttcgtac ttactcgaaa aagatgcggc cttgtaccaa tcttactttg ataagaaata
     4441 tcaaaaagtt gtcgctctaa cctttgatga tggtccaaat ccagcaacga ccccgcaggt
     4501 attagagacc ctagctaaat atgatattaa agcgactttc tttgtgcttg ggaaaaatgt
     4561 ttctgggaat gaggacttgg tgaagaggat aaaatctgaa ggtcatgttg ttggaaacca
     4621 tagttggagc catccgattc tctcgcaact ctctcttgat gaagctaaaa agcagattac
     4681 tgatactgag gatgtgctaa ctaaagtgct gggttctagt tctaaactca tgcgtccacc
     4741 ttatggtgct attacagatg atattcgcaa tagcttggat ttgagcttta tcatgtggga
     4801 tgtggatagt ctggactgga agagtaaaaa tgaagcatct attttgacag aaattcagca
     4861 tcaagtagct aacggctcta tcgttttgat gcatgatatt cacagtccga cagtcaatgc
     4921 cttgccaagg gtcattgagt atttgaaaaa tcaaggttat acctttgtga ccataccaga
     4981 gatgctcaat actcgcctaa aagctcatga gctgtactat agtcgtgatg aataagcaag
     5041 aaaaaatagg tctgttagat atttgacaga cttatttttt acagaagata gtactactta
     5101 aaaaatgttt tatgctataa ttgatgaata aaatagaagg agaagcatat gaatacctat
     5161 caattaaata atggagtaga aattccagta ttgggatttg gaacttttaa ggctaaggat
     5221 ggagaagaag cctatcgtgc agtgttagaa gccttgaagg ctggttatcg tcatattgat
     5281 acggcggcga tttatcagaa tgaagaaagt gttggtcaag caatcaaaga tagcggagtt
     5341 ccacgtgaag aaatgttcgt aactaccaag ctttggaata gtcagcaaac ctatgagcaa
     5401 actcgtcaag ctttggaaaa atctatagaa aaactgggct tggattattt ggatttgtat
     5461 ttgattcatt ggccgaaccc aaaaccgctc agagaaaatg acgcatggaa aactcgcaat
     5521 gcggaagttt ggagagcgat ggaagacctc tatcaagaag ggaaaatccg tgctatcggc
     5581 gttagcaatt ttcttcccca tcatttggat gccttgcttg aaactgcaac tatcgttcct
     5641 gcggtcaatc aagttcgctt ggcgccaggt gtgtatcaag atcaagtcgt agcttactgt
     5701 cgtgaaaagg gaattttatt ggaagcttgg gggccttttg gtcagggaga actatttgat
     5761 agcaagcaag tgcaagaaat cgcagcaaat cacggaaaat cgattgctca gatagccttg
     5821 gcctggagct tggcagaagg atttttacca cttccaaaat ctgtcacaac ctctcgtatt
     5881 caagctaatc ttgattgctt tggaattgaa ctgagtcatg aggagagaga aaacttaaaa
     5941 acgattgctg ttcaatcggg tgctccacga gttgatgatg tggatttcta gaaaatcata
     6001 aaaagaattg tacattattc taatttttga tataatagtc agcaggaaag aaagtcttat
     6061 ggcgttcttc aagcgagctt gggatagtgg gagccaagta gggcaaaata atgagctggc
     6121 gctttctgta gtattttcaa aaacaatgaa gtaataaatt agggtggaac cgcgtttctg
     6181 acgcccctag gttaaatcaa cctaggattg tcggacgcgg ttcttttgct tattcagtct
     6241 attgtgtgaa agaaaggaga gccgtggaca acctttatct tgtaaaagac gatagtcaac
     6301 tagctacatt tcgtgatttt gtagtaagaa atactgaaaa gttgaaagat tatcaatctt
     6361 ttttaaagaa tgaacttgca gtctgtgatt taccgcaagc cgttatttgg tcagatttta
     6421 atgctgctac acagattatt agggaaagcg ctgttccagc ctatacaaat aatagacgaa
     6481 tggttatggc gcctgattta gctgtttgga aagagttgta tttgtatcaa ttgatggact
     6541 acgagtgttc tcagcaaact caagcaatag aaagtcacta tcattcttta tctgaaaatt
     6601 tcctcttaca gattgtagga catgagttag ctcattggtc ggagcatttt ttagatgatt
     6661 ttgatggtta tgactcttat atctggttcg aagaggggat ggttgaatat attagtcgca
     6721 agtatttctt gacagaagag gaatttcaag cggaaaaaat ttgtaatcaa tctctcgtag
     6781 aactttttca gaagaagtat ggttggcatt cattgaatga ttttggttct tcgacttatg
     6841 ataagaacta tgcaagtatt ttttatgaat actggcgcag ctttttgaca gtagataagt
     6901 tggtagaaaa tttaggtagt gtacaagcgg tcttagattc ttatcattta tgggcaaata
     6961 cagaaaaaac ttttcccttg ttagattggt ttgttcagca gaaattaatt gaaaaagaaa
     7021 tataaaaact aaaggagtaa acaatgtcta agaaattgac atttcactgc gtcagtggca
     7081 gaaacctcct tacagtcgga ctgccccacg ctcagcacta gagtgcctga gctagacgca
     7141 gtactaactc gtcttgcctc gtatgatcga cgaggcagac tcatgtcgca agtaatttat
     7201 ataaaaagga gtaaacaatg tctaagaaat tgactttcca ggaaatcatc cttactttgc
     7261 aacaattttg gaatgaccaa ggttgtatgc ttatgcaggc ttatgataat gaaaaaggtg
     7321 cgggaacaat gagtccttac actttccttc gtgctatcgg acctgagcca tggaatgcag
     7381 cttatgtaga gccatcacgt cgtcctgctg acggtcgtta tggggaaaac cctaaccgtc
     7441 tctaccaaca ccaccaattc caggtggtca tgaagccttc tccatcaaat atccaagaac
     7501 tttaccttga atctttggaa aaattgggaa tcaatccttt ggagcacgat attcgttttg
     7561 ttgaggacaa ctgggaaaac ccatcaactg gttcagctgg tcttggttgg gaagtttggc
     7621 ttgacggaat ggaaatcact cagttcactt atttccaaca agtcggtgga ttggcaactg
     7681 gccctgtgac tgcggaagtt acctatggtt tggagcgctt ggcttcttac attcaagaag
     7741 tagactctgt ctatgatatc gagtgggctg atggtgtaaa atacggagaa atctttatcc
     7801 agcctgagta tgagcactca aaatattcat ttgaaatttc ggaccaagaa atgttgcttg
     7861 aaaactttga taagtttgaa aaagaagctg gtcgtgcatt agaagaaggc ttggtacacc
     7921 ctgcctatga ctatgttctc aaatgttcac atacctttaa tctgcttgac gcgcgtggtg
     7981 ccgtatctgt aacagagcgt gcaggctata tcgctcgtat ccgtaacttg gcccgtgtcg
     8041 tagccaaaac ctttgtcgca gaacgcaaac gcctaggcta cccacttttg gatgaagaaa
     8101 caagagctaa actcctagca gaagacgcag aataaagaga gtgacaaatt acgaaaatgg
     8161 gcgaacagag tgagccctga gccagttgcc gcagtgatga aggtatcctt agtgaaacta
     8221 aggatactag gcaaaattgg agacttttgg ctccaatttt agcaatgaaa caacgaagtt
     8281 ggttgcttgc gtgccaatca cataaggcaa actggaaaat aaaaagatac ttttcggaga
     8341 aaaaacatga caaaaaactt attagtagaa ctcggtcttg aagaattacc agcctatgtt
     8401 gtcacaccaa gtgaaaaaca actaggcgaa aaaatggcag ccttcctcaa ggaaaaccgc
     8461 ctgtcttttg aagccattca aaccttctca acaccacgtc gtttggctgt tcgtgtgact
     8521 ggtttatcag acaaacagtc tgatttgaca gaagatttca agggaccagc aaaggaaatt
     8581 gccttggata gtgatggaaa cttcaccaaa gcagctcaag gatttgtccg tggaaaaggc
     8641 ttgactgttg aagatatcga attccgtgaa atcaagggtg aagaatatgt ctatgtcact
     8701 aaggaagaag ttggccaatc agttgaagcc attgttcctg gtgttgtaga tgtcttgaag
     8761 tcattgactt tccctgtcag catgcactgg gctggaaata gctttgaata catccgccct
     8821 gttcacactt taactgttct cttggatgag caagagtttg acttggattt ccttgatatc
     8881 aagggaagtc gtgtgagccg tggccatcgt ttcttgggga aagaaaccaa aattcagtca
     8941 gcattgagct atgaagaaga ccttcgtaag cagtttgtaa tcgcagatcc atgtgaacgt
     9001 gagcaaatga ttgttgacca aatcaaggaa attgaggcaa aacatggtgt acgtatcgaa
     9061 attgatgcgg atttgctgaa tgaagtcttg aatttggttg aatacccaac tgccttcatg
     9121 ggaagttttg atgctaaata ccttgaagtt ccagaagaag tcttggtgac ttctatgaag
     9181 gaacaccagc gttactttgt tgttcgtgat caagatggaa aactcttgcc aaacttcatt
     9241 tctgttcgta acggaaacgc agagcgtttg aaaaatgtca tcaaaggaaa tgaaaaagtc
     9301 ttagtagccc gcttggaaga cggagaattc ttctggcgtg aagaccaaaa attggtgatt
     9361 tcagatcttg ttgaaaaatt aaacaatgtc accttccatg agaagattgg ttcccttcgt
     9421 gaacacatga ttcgtacggg tcaaatcact gtacttttgg cagaaaaagc tggtttgtca
     9481 gtggatgaaa cagttgacct tgctcgtgca gcagccattt acaagtttga cttgttgaca
     9541 ggtatggttg gtgaatttga cgaactccaa ggaattatgg gtgaaaaata cacccttctt
     9601 gctggtgaaa ctccagcggt ggcagctgct attcgtgaac actacatgcc tacatcagct
     9661 gaaggagaac ttccagagag caaggtcggc gcagttctag ccattgcaga caaattggat
     9721 acgattttga gtttcttctc agtaggattg attccatcag gttctaatga cccttatgcc
     9781 cttcgtcgtg caactcaagg tgtggttcgt atcttggatg cctttggttg gcacattgct
     9841 atggatgagc tgattgatag cctttatgca ttgaaatttg acagtttgac ttatgaaaat
     9901 aaagcagagg ttatggactt tatcaaggct cgtgttgata agatgatggg ctctactcca
     9961 aaagatatca aggaagcagt tcttgcaggt tcaaactttg ttgtggcaga tatgttggaa
    10021 gcagcaagtg ctctcgtaga agtaagcaag gaagaagatt ttaaaccatc tgttgaatca
    10081 ctttctcgtg cctttaacct ggctgagaag gcagaagggg ttgctacagt tgattcagca
    10141 ctatttgaga atgaccaaga aaaagctttg gcagaagcag tagaaacact cgttttatca
    10201 ggacctgcaa gtcagcaatt gaaacaactc tttgcgctta gcccagtcat tgatgctttc
    10261 tttgaaaata ctatggtaat ggctgaagat caggctgtcc gtcaaaatcg tttggcaatc
    10321 ttgtcacaac taaccaagaa agcagctaag tttgcttgtt ttaaccaaat taacactaaa
    10381 taaaatttga taaacggact ttatcttatt acaaaggaga agaaatggat ccgaaaaaaa
    10441 ttgctcgtat caatgagctt gctaaaaaga aaaaaacaga aggcttaaca ccagaagaaa
    10501 aagtggaaca agccaaacta cgtgaggagt acatcgaagg ttatcgccgc gctgttcgtc
    10561 accacattga aggaatcaaa attgtggacg aagaaggaaa cgatgttaca ccagaaaaac
    10621 tacgccaagt acaacgtgaa aaaggattac atggccgtag tcttgatgat ccaaattcat
    10681 aataatactc ttcgaaaatc aaattcaaac cacgtcagct tcaccttgcc gtacttaagt
    10741 acagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtata tgtattcttt
    10801 cttttaacaa agatagatga aacgataaca aagagactag cagtttgtgt ttgctagtct
    10861 tttttcgcta aaaaaggaac cataatggtt cctaaaaact atcattagta acttgcaccg
    10921 gctgtagcgt ctgcgtcacc accgtggcct ccagcatccc ctgaatcaga agcgccagaa
    10981 gtagcatcgg cgtctccatg acctccggca gcaggagcaa atggtccgct accacccacc
    11041 aaacgttgac cagtctcttt taggtaccag tcaagccatg gttggaagtt aaagacgatt
    11101 tcattgatac cagcgtatga tccatcagga tagtacattg cttggtagtt gtgagtgttg
    11161 ataacacctg caggagaacc tggaacgatc gtacggacgt attcttggtt tccgttgcga
    11221 agtgttccga taacccactc tacgttcttc atacgtgctg gtggaagaga accatgaaca
    11281 gtcgacatac ggctacctga ttgaggtggt acacgtttag cgaacatagt gtctggatct
    11341 tggtgagcgt tgttgtagta gaggaattgg ttgttgtcgt cagcgtatgt caattcaaat
    11401 ggcatagctt tcaagaacat atcaatttgg ttaactgtta ggataccgtg gtccaatttg
    11461 acataggtat caccagaaac agcaccagtg aatgctgcaa ctttttctac ccattctgga
    11521 tcgtcagggt caacttctgt gatggttgta gcgattggtt ttccacaatc caagtcttct
    11581 gattcgattg gttttggttt tttcaatttc gaaacgactc ctacgtattt aacaaagtta
    11641 tctaagcaag tttcaaggaa tttaacagtg ccttcgttgg tgatatttcc gttgttatca
    11701 aaagcttcct tagctttacc aagaaggaat tcgttacctg gaagcgtgta ggcattaaca
    11761 cctggagcat caaggatttt acgaaggtga acttgagcac gtgatgttcc ttggtcatag
    11821 tatgatgcac ccacaatcat aacaggcttg ttttcaaatg gatgaacttc gtatgaaagc
    11881 cattcaagta cagatttgag tgaagctgag atagtgtggt tatgctcagg agtagcaatg
    11941 ataacaccat ctgcacgagt aattttgtta tataaataac gtaattggaa actttcatcc
    12001 catttttcat cttggttaaa cattggaact tcgtcaattt caagaacttc taattcaaat
    12061 ttgagtttga agtagcgacg gataaattcc aagagcttac ggttatatga ttgatcgtag
    12121 tttgatccaa caagtccaac aaatttcatt ctttttggtc tcctatctta caaattttcc
    12181 cagtcaaagt cttcagcatc tttgcgaagt aattcttgtg cattacgtaa tttttctgtg
    12241 atttttacaa agatacggaa gtcatcaaag atggcatcca atttcttgat aacatcaagg
    12301 tcaaccaagt cgccacttgg gttaaatgct tgaagagagt gtgagagcaa gaattcatct
    12361 ggaagaacat ttgccttgat ttcaggagca ttcaagattt gacgaagttg caattgggca
    12421 cgagatgaac caagcgtacc gtaagaagca cctgtaatca tgattggttt gttcaaaagt
    12481 gggtaaatac cataagataa ccaagcaaga gcgctcatca aaacagctgg aatagagtga
    12541 tcatactcag gagtaccgat aataacgcca tctgcctctt cgattttagc agcaatttcc
    12601 aatatttcag caggtacttg cttgtcagct ggtttgttga agacaggaat ggccttgatt
    12661 tcaacaagtt caatttcagc tttgtcagta aagtgttttt gcatgtattg aagcaattga
    12721 cggtttgtag aacgttttga atttgttcca acaatagcaa taagttttaa catgagattt
    12781 cctttctctt tttacataat acaattttaa aattccattg aaacagttgt ctctatagag
    12841 taggaattcc tgaagaacag cttaggtggc cttctttatc gatgaggatg acttcgatgc
    12901 cctccaaact ttcgacttgc cagaggatag aagcaggtct ttctccaaag agtcgagtcg
    12961 tccagatttc gccatcgact gatttatcag agatgattgt tagactcgct agttccgttt
    13021 caacaggata tcctgtttga ctgtcaaaaa tgtgatggta atcttgtcca tcgacggtca
    13081 ggtgacgttc ataaatgcct gaagtcacga cagatttatt gacaacaggg atggtcatta
    13141 aatgatttcc cctaggattg gctgggtctt gaatcccgat ttgccatggg ttatcccctc
    13201 ttgcctgatt ttttccaatg gtcaggatat tccctcccag attgatcaag gcagaagtca
    13261 ccccctcttt cctaagaaat tgggcaacct tatccgcact gtatcctttg gctaaacaac
    13321 ctagatcgat cttcattcct ttctgtttta aaaacacagt agaagtagaa gaatctaact
    13381 cgataccatg aggattgatt agaggcagca ccgattcaat ttcttgaggc tgggcgacct
    13441 tggcatctga aaaaccgata cgccaggttt gaattaaggg accaatgctg atattgaggt
    13501 ggctagagag cgctaggcta tgctctaacc caagtgaaat cagctcaaac aggtctggat
    13561 gaaccgtgac gggggctatt cctgcttgat aattgatttc catcaactca gattcttgac
    13621 tattggcgtt gaagcggtat tcaagttctt tgagcaagtc aaaggatttt tggagaaaga
    13681 tatcggcttg ctcatccact aatgaaatag tgatagtagt ccccattagc cgttcagaat
    13741 gtgaacgaag agtcaagcta ccaactcctt tctcttatag aaaataagtt gtaatatcaa
    13801 ataatcatct aaattgaagc ccttacattt cattttcatg ttattataat accataaagt
    13861 tagaattttc acaaacaaaa tttggaaaaa gtcaagaaat atgctcataa aattcatcag
    13921 gcttgaaaac aggataaatg gggaattatt tttgataaaa aatgctgaaa taatagtacc
    13981 ccccttgtaa acgctaacgg taaatggtat actagtaagg taaatttaga atgaaggcag
    14041 gaaattttta tgagtaaaat cgttgtagtc ggtgctaacc acgctggtac agcatgtatc
    14101 aataccatgt tggataattt tggaaatgag aacgaaattg ttgtatttga ccaaaactct
    14161 aacatctctt tcctaggatg tggaatggct ctttggattg gtgaacaaat tgacggtgct
    14221 gaaggcttgt tctattctga taaagaaaaa ttggaagcta aaggtgctaa agtttacatg
    14281 aactcacctg ttctttcaat cgactatgat aacaaagtag ttacagcgga agttgaagga
    14341 aaagagcaca aagaatcata cgaaaaattg attttcgcta caggttctac accaatcttg
    14401 ccaccaatcg aaggtgttga aattgttaaa ggaaaccgcg aatttaaagc aactcttgaa
    14461 aacgtacaat tcgtgaaatt gtaccaaaat gctgaagaag ttatcaataa actttctgac
    14521 aagagccaac acctcgaccg tatcgccgtt gttggtggtg gttacatcgg tgttgaactt
    14581 gctgaagcct ttgaacgtct tggaaaagaa gttgtccttg ttgatatcgt tgatactgtc
    14641 ttgaacggtt actatgacaa agacttcaca caaatgatgg cgaagaactt ggaagatcac
    14701 aacatccgct tggctctagg tcaaactgtt aaagcaatcg aaggtgacgg taaagttgaa
    14761 cgcttgatta ctgacaaaga aagctttgac gtggatatgg ttatccttgc agttggtttc
    14821 cgtccaaaca cagcccttgc aggtggtaag atcgaactct tccgcaacgg tgccttcctt
    14881 gtagacaaga aacaagaaac atctatccca gacgtttacg ctgttggtga ctgtgcgact
    14941 gtttatgaca atgctcgtaa agatacaagc tatatcgctc ttgcttcaaa tgctgttcgc
    15001 actggtatcg ttggtgccta caatgcttgt ggacatgaat tggaaggaat cggtgttcaa
    15061 ggttcaaatg gtatctcaat ctacggtctt cacatggttt caactggttt gactcttgaa
    15121 aaagcgaaag ctgctggtta caacgcaact gaaacaggct ttaacgatct tcaaaaacca
    15181 gaattcatga aacatgacaa ccatgaagta gcaattaaga ttgtctttga caaagatagc
    15241 cgtgaaattc ttggtgccca aatggtttcc catgatattg caattagcat gggaatccac
    15301 atgttctcac ttgctatcca agagcatgtg acaattgata aattggcatt gacagacctc
    15361 ttcttcttgc cacacttcaa caaaccatac aactacatca caatggctgc ccttacggct
    15421 gaaaaataaa aatgaatgag ctatctggcc ttaagttaag gtcagatagt ttttagctaa
    15481 tctgtcccca tacaattata gtttttttat cttgtgcttc attctgttct gacttaaaat
    15541 gaaaaggtag ctaccaatac aaatgatgag gataaaacaa atgactgaaa atcgttatga
    15601 actaaataaa aacttggcac agatgctcaa gggtggtgtt attatggatg tgcagaatcc
    15661 tgaacaggct cgtatcgcag aagctgctgg tgcggcagct gtgatggcct tggaacgaat
    15721 tccggctgat attcgtgcag ctggaggagt ttcccgcatg agcgacccaa agatgattaa
    15781 ggaaatccaa gaagcggtta gtattccagt aatggctaag gtcagaatcg ggcattttgt
    15841 tgaagctcag attttagagg ctattgaaat tgattatatc gacgagagtg aagttctatc
    15901 tccagctgat gaccgtttcc atgtggacaa gaaagaattc caagttcctt ttgtctgtgg
    15961 tgctaaggat ttgggtgaag ccttgcgtcg tatcgctgaa ggtgcttcca tgattcgtac
    16021 caaaggagaa ccagggacag gggatatcgt ccaagctgtt cgtcatatgc gtatgatgaa
    16081 tcaggaaatt cgccgcattc aaaacttacg tgaggacgag ctttatgttg ctgccaagga
    16141 tttgcaagtc cctgtagaat tggtccaata tgttcatgaa catggaaaat tgccagttgt
    16201 aaatttcgct gctggaggtg ttgcaacgcc agcagatgct gcgttaatga tgcaactagg
    16261 ggcagagggg gtctttgtcg gttcaggtat tttcaagtca ggagatcctg ttaaacgagc
    16321 gagtgccatt gttaaggctg tgactaactt ccgtaatcct caaatcctag ctcaaatctc
    16381 tgaagattta ggagaagcca tggttggtat taatgaaaat gaaatccaaa ttctcatggc
    16441 tgaacgagga aaatagatga aaatcggaat attggccttg caaggggcct ttgcagaaca
    16501 tgcaaaagtg ctagatcaat taggtgtcga gagtgtagaa ctcagaaatc tagatgattt
    16561 tcagcaagat cagagtgact tgtcgggttt gattttgcct ggtggtgagt ctacaaccat
    16621 gggcaagctc ttacgtgacc agaacatgct acttcccatc cgagaagcca ttctatctgg
    16681 cttaccagtg tttgggacct gtgcgggctt aattttgctg gctaaggaaa tcacttctca
    16741 gaaagagagt catctaggaa ctatggatat ggtggtcgag cgtaatgctt atgggcgcca
    16801 attaggaagt ttctacacgg aagcagaatg taagggagtt ggcaagattc caatgacctt
    16861 tatccgtggt ccaattatca gcagtgttgg agaagatgta gaaattctag caacagttga
    16921 taatcaaatc gttgcagccc aagaaaaaaa tatgttggta acttcttttc atccagaatt
    16981 gacagatgat gctcacttac accagtactt tatcgaaatg tgtaaagaaa aaagacagta
    17041 aaaaagctca aaaaatcact tcctgtgcta tactgtaatt gaaatttttt tagtttttgc
    17101 gttagaactg tttcctcagt cctagcgcct tttctttttg ataagtctgc ttggtggaga
    17161 gtagtttgta aacgattctg agaatcttat gagcacaagc aatgacggct ttcatcttgc
    17221 ttcctctttg ggaaattcga ttgtaaaact ctaagcaggc agagcctgct tagagtttta
    17281 catatgctac tatctttgtt atagctaact taaattctca tttattaagt atacctaag
//
LOCUS       DAVKUR010000042        17022 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKUR010000042 DAVKUR010000000
VERSION     DAVKUR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.042"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            314..1360
                     /gene="pheS"
                     /locus_tag="VW749_001563"
     CDS             314..1360
                     /gene="pheS"
                     /locus_tag="VW749_001563"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0175581.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1360..1869
                     /locus_tag="VW749_001564"
     CDS             1360..1869
                     /locus_tag="VW749_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175582.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1946..4351
                     /locus_tag="VW749_001565"
     CDS             1946..4351
                     /locus_tag="VW749_001565"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0175583.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4419..5420)
                     /locus_tag="VW749_001566"
     CDS             complement(4419..5420)
                     /locus_tag="VW749_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0175584.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTDSGIAPVTVIVKKSYDFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5576..6065
                     /locus_tag="VW749_001567"
                     /pseudo
     CDS             5576..6065
                     /locus_tag="VW749_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6149..6415
                     /locus_tag="VW749_001568"
     CDS             6149..6415
                     /locus_tag="VW749_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175585.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6676..8925
                     /gene="metE"
                     /locus_tag="VW749_001569"
     CDS             6676..8925
                     /gene="metE"
                     /locus_tag="VW749_001569"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0175586.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLSAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFTTERVGENAELRARIAG
                     LTDADYTRLPVFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8989..9855
                     /gene="metF"
                     /locus_tag="VW749_001570"
     CDS             8989..9855
                     /gene="metF"
                     /locus_tag="VW749_001570"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0175587.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10540..12753
                     /gene="pnp"
                     /locus_tag="VW749_001571"
     CDS             10540..12753
                     /gene="pnp"
                     /locus_tag="VW749_001571"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0175588.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12769..13386
                     /gene="cysE"
                     /locus_tag="VW749_001572"
     CDS             12769..13386
                     /gene="cysE"
                     /locus_tag="VW749_001572"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0175589.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13398..14282
                     /locus_tag="VW749_001573"
     CDS             13398..14282
                     /locus_tag="VW749_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175590.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14369..15712
                     /locus_tag="VW749_001574"
     CDS             14369..15712
                     /locus_tag="VW749_001574"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0175591.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15705..16091
                     /locus_tag="VW749_001575"
     CDS             15705..16091
                     /locus_tag="VW749_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0175592.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16095..16979
                     /locus_tag="VW749_001576"
     CDS             16095..16979
                     /locus_tag="VW749_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0175593.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         5052 a         3329 c         3896 g         4745 t
ORIGIN      
        1 gctataaagt tagataagaa taagctaaca agcagaagta agataggtct tgcaagaatg
       61 gtaaaaatct gataaactaa gtagtaattg aataggaatc tgaaagacta gtagcccaag
      121 ggaagtatat cagggaggag agccgtgact gcaagctctc tatatgaaag ctgggtgaat
      181 tcacttgcgc atggatttag aaatgaaggt ctgacttgtc agatgaaaac ggatggtacc
      241 gcgtgtcaac gctccgagtg gagtttttgg catgtggttt tctttttatc tacgagagac
      301 tgatggagga aatatgtcaa ctattgaaga acaattaaaa gcgcttcgcg aagaaacgct
      361 ggctagcttg aagcagatta ctgctggaaa tgaaaaagag atgcaagatt tgcgtgtctc
      421 tgtccttggt aaaaagggtt cgctcactga aatcctcaaa gggatgaaag atgtttctgc
      481 tgagatgcgt ccaatcatcg ggaaacacgt caatgaagct cgtgatgtct tgactgctgc
      541 ttttgaagaa acagctaagc tcttggaaga aaagaaagtc gcggctcaac tggctagcga
      601 gagtatcgat gtgacgcttc caggtcgtcc agttgcgact ggtcaccgtc acgttttgac
      661 acaaaccagt gaagaaatcg aagatatctt catcggtatg ggttatcaag tcgtggatgg
      721 ttttgaagtg gagcaagact actataactt tgaacgtatg aaccttccaa aagaccaccc
      781 agctcgtgat atgcaggata ctttctatat cactgaagaa atcttgctcc gtacccacac
      841 gtctccagtt caggcgcgtg ctatggatgc ccatgatttt tctaaaggtc ctttgaagat
      901 gatctcgcca gggcgtgtct tccgtcgcga tacggacgat gcgacccaca gtcaccaatt
      961 ccaccaaatc gaaggcttgg tagttgggaa aaatatctct atggctgatc ttcaaggaac
     1021 gcttcagttg attgtccaaa aaatgtttgg tgaagagcgt caaattcgtt tgcgtccatc
     1081 ttacttccca ttcacagagc catctgttga ggtggatgtt tcttgcttca agtgtggtgg
     1141 agaaggctgt aatgtatgta agaaaacagg ttggatcgaa attatggggg ccggtatggt
     1201 tcacccacgt gtccttgaaa tgagtggtat cgatgcgact gtatactctg gctttgcctt
     1261 tggtcttgga caagagcgtg tagctatgct ccgttatgga atcaacgata tccgtggatt
     1321 ctaccaagga gatgtccgct tctcagaaca gtttaaataa tgattagaaa agtagaaatg
     1381 gcagatgttg aggtgttggc taaaattgcc aaacaagcct ttcgtgaaac ctttgcgtat
     1441 gataatacgg aagagcagtt acaggaatac tttgaagagg cttatagtct gaaaactttg
     1501 tcaactgagt tgggaaatcc tgactctgaa acctatttca ttatgcatga ggaggagata
     1561 gctggttttc tcaaagtcaa ctggggaagt gctcaaactg agagagaatt agaggacgct
     1621 tttgaaattc aacgcctcta tgtgctacaa aaattccaag gatttggact aggtaagcaa
     1681 ctgtttgaat tcgcacttga acttgctaca aaaaatagtt tttcttgggc ttggttaggt
     1741 gtttgggagc ataatacaaa agctcaagcg ttttataatc gatatggttt tgaaaaattt
     1801 agccaacatc attttatggt tggtcaaaaa gtagatacgg attggttact gagaaagaaa
     1861 ttaaggtaag aagaggattc ttctattgaa atgataggaa aggaaaagaa ctagagtgac
     1921 aactgtcatt ctggagaact aaattatgct tgtatcttat aaatggttaa aagaattggt
     1981 ggacattgat gtgccatcac aagagttggc tgaaaaaatg tcaactacag gaatcgaggt
     2041 agagggtgtc gaatcaccag ctgctggtct ctcaaaaatt gtcgtcggtg aggtcttgtc
     2101 ttgcgaagat gtgccagaga ctcacctcca tgtttgtcag gttaacgttg gcgaagaaga
     2161 agagcgtcag atcgtttgtg gtgccccaaa tgtgcgtgct gggatcaagg tcatggtggc
     2221 tcttccagga gctcgtatcg ctgataacta caaaatcaaa aaaggaaaaa tccgtggttt
     2281 ggagtcactt ggaatgatct gttcacttgg tgaattggga atttctgact cagttgtgcc
     2341 taaggaattc gcagatggca tccaaatctt gccagaaaat gccgtgccag gtgaggaagt
     2401 cttttcttac ctagacttgg atgatgaaat catcgaactt tccatcacac caaaccgtgc
     2461 agatgccctt tctatgtgtg gagtggctca cgaagtggca gccatctatg acaaggcagt
     2521 caactttaaa gaatttactc taacagaaac taatgaatct gcggcagatg ccctttctgt
     2581 cagcattggg acagacaagg cgccttacta tgcagctcgt atcttggaca atgtgactat
     2641 cgcaccaagt ccacaatggt tgcaaaacct tctcatgaac gaaggcatcc gtcccatcaa
     2701 taacgttgta gacgtgacaa actacatcct gctctacttt ggtcaaccta tgcatgcttt
     2761 tgacttggac acatttgaag ggactgacat ccgtgtgcgt gaagcgcgtg ctggtgaaaa
     2821 gttggtgacc ttggacggtg aagaacgaga cttggctgag acagacctcg tgattacagt
     2881 tgctgacaaa ccagtagccc ttgccggtgt tatgggtggt caggctacag aaatttctga
     2941 aaaatctagt cgtgttatcc ttgaagctgc tgtttttaat ggcaaatcta tccgtaagac
     3001 aagtggtcgc ctgaaccttc gttctgagtc atcttctcgc tttgaaaaag gaattaatgt
     3061 ggcaacagtt aatgaagccc ttgatgcggc agctagcctg attgcggaac ttgcaggtgc
     3121 gacggtgcgt aagggtatcg tttcagcggg tgagcttgat acttcagatg tagaagtttc
     3181 ttcaactctt gctgatgtta accgtgtcct cggaactgag ctgtcttatg ctgatgtcga
     3241 agacgtcttc cgtcgtcttg gctttggtct ttctggaaat gcagacagct ttacagtcag
     3301 cgtaccacgt cgtcgttggg atatcacaat cgaagctgat ctctttgaag aaatcgctcg
     3361 tatctatgga tatgaccgtt tgccaaccag ccttccaaaa gacgatggta cagctggtga
     3421 attgactgtg acacaaaaac tccgccgtca agttcgtacc attgctgaag gagcaggttt
     3481 gacagaaatc atcacctata ctctaacaac tcctgaaaaa gcagttgagt ttacggctca
     3541 accaagtaac cttacggaac tcatgtggcc aatgactgtg gatcgttcag tcctccgtca
     3601 aaatatgatt tcaggtatcc ttgataccgt tgcctacaac gtggctcgta agaataaaaa
     3661 cttggccctt tacgagattg gaaaagtctt tgaacaaaca ggtaatccaa aagaagaact
     3721 tccaaatgaa atcaacagtt ttgcctttgc cttgacaggc ttggttgctg aaaaagattt
     3781 ccaaacagca gcagttccag ttgatttctt ctatgctaag ggaatccttg aagcgctctt
     3841 tactcgcttg ggactagaag tgacctatac agcaacagct gagattgcca gccttcaccc
     3901 aggacgtaca gcagtcattt cactcggtga ccaagttctt ggttttcttg gccaagtgca
     3961 tccagtcact gccaaggctt acgatattcc agaaacgtat gtagctgagc ttaacctttc
     4021 agccatcgaa ggggcgctcc aacctgctgt tccatttgtg gaaatcacga aattcccagc
     4081 agtcagccgt gacgttgccc ttctcctcaa ggcagaagta actcaccaag aagttgtaga
     4141 tgctatccaa gctgccggcg tgaaacgttt gacagatatc aaactctttg acgtcttctc
     4201 aggtgagaaa ttgggacttg gtatgaagtc catggcttat agcttgacct tccaaaatcc
     4261 agaagatagc ttaacggacg aagaagtcgc acgctatatg gaaaaaatcc aagcatcgct
     4321 cgaagaaaaa gtgaatgcag aagtgcgtta aacgatagta ggatataaat tccccctcta
     4381 gtttatgaac actagagggg tgattttata taaaataatt aaaatgtgat ttctgtaaaa
     4441 atacatctat gatcagagtt ttgaaaactt acaatgtcta aatctttaac atagtagtgg
     4501 tttttaggca ataaaatatg atctatcgtt gcattaaaaa gttttggact ttggctattc
     4561 caagttcctc tttcaaaagg tggcagtgca tttaatgcgt ccctatgaga gcttattttt
     4621 gcaagtgctc catgacgcat agttgcatta aaatcacctg caataatagc ctttggatat
     4681 tttgaagcca attgattatg aatgatgttt aagtcttgct tccagatttc cattaaacct
     4741 ggcagaggag gagcagtatg caaagcaatg atatctggta tatcttgttt tctcgaatgt
     4801 aatacaattg tcccgaaccg tgttgtatga aaagtttcag cttttgtata gaaatcgtaa
     4861 cttttcttga caatcacagt cacaggagct attccactgt cagtaggtgg agaagtaaaa
     4921 atatcatagt tggccataga aagtccaact tgatgaaaca atagtttgat tctctggttt
     4981 tcttgctcac ctctgatatt ggtagctagt tcagggaata tagccatatc ggcgtcaaaa
     5041 tggctaaaaa ttcgctcaat atgttgtgct tctatttgat tagcgacgtt ccaagttact
     5101 aattttaagg ttttagtctt atttgatgcg gaagaaaggg ttttatctgt tccgaataat
     5161 agtaatatga gcgataataa gagcaaaatg ccagagtaaa accgtatttg tttatttttc
     5221 ttgtaaaaag atagggaaaa aaatacgaaa cttaaaatgg cagccatagt tgcagtagct
     5281 aaggggaagg cataaatctg tgccaagata ggtctggtag atagccaaat attaagatta
     5341 gaagatggaa aaaaagaata agttatgata gggataacaa agagaatgac cgaaagggca
     5401 gagagaaatg ttttaatcat tgtgtgagta cctcaatttg caatggttgc tcggagctaa
     5461 tgtgactttg tgactttact tgattgatat tctttttctt gtcttcctta tagattaagt
     5521 acaacccaag taaaaaaagt ccaatttaag attgaaatga ttaaaaggca cagagatgca
     5581 agacaattat actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag
     5641 atggaaaaaa gaaggaaaat caaatagaga agttgcctct ctacttggaa aagctcctca
     5701 aactatccac actgaaatca agcgtgggac agtccgaaaa tgtcttggaa aagggcgctt
     5761 caaagaggtt tattctgccg actacgctca acagtcttat gaaaacaatc gcaagcgctc
     5821 ggtcaagaaa tcaagcttga ccaaggaact aaaggaaaag attctccact atacataacc
     5881 aaaaattttt gcctgaaatg atggtgatgg ctaaaggggt taacgtggga atttcaacca
     5941 tttactattg gattcatcat ggaaagttgg ggttaagcaa acaggatttg ctttatccta
     6001 gaaaaggaaa atctgttaag aaacaagtta gtcccaattt taaacccgct gatcaatcta
     6061 tcgaatcata attcgctcat ttttttaaaa atacatagac gtaaaaaaaa gagggttaag
     6121 tgatgaagaa tagtgctatt gggagtaatt ggaaggatgt ccatctgagc tctttagcaa
     6181 ggaggaaatc cttgaaagtg atatgcgagt ggctatcatg agcgagttga ttgaggctag
     6241 gtatgaacaa ggaatcagtc agaaaaagct ggaagaagtc agtggaataa gccagcctgt
     6301 catagctagg atggagacag gaaagactag tcctcagttg gatacagtct taaaagtcct
     6361 agccagttta ggaaagacac tagcaatcgt cccacttgaa cagggaaaaa gttgactaga
     6421 atcagttata gtcttttcta ataacaagcc atagtcactt ataagaatta ctaataacgc
     6481 gtttgagcat tctaactaaa atacagctat aaaacaagct atacaaagga tttgagacgt
     6541 ttgcttcaag tctttttctt ttgtccgaaa cagatatata gtttcaaact atatcaaacc
     6601 ctaatttttt acaattatac agacgctttc ttttctgtta agatagtttc aacaacaaat
     6661 tttggaggac acatcatgtc aactacaatc gtcggtttcc ctcgtttggg cgaattccgt
     6721 gaattaaaat ttacaactga aaaatacttt agaaaagaaa tctcagagga agaactttta
     6781 tcagcagcaa aagacttgcg tgctaaacac tggaacattg tcaaagaaaa aggcatcact
     6841 gaaattccat caaatgactt ttctcactat gataacttcc tagatgcggc tttccttttc
     6901 aacgtggtgc ctgcatccgt tcaaaacttg gacttgtctg accttgagcg ctacttcgct
     6961 ttgggacgtg gttaccaggg agaaaaaggg gacgttcgcg cccttccaat gaagaaatgg
     7021 ttcaacacta actaccacta catcgttcct aaatttgaaa aagacactca agtaaaattg
     7081 gctggtcaca agattttcga tgagttccaa gaagccaaag aacttggatt gaacactcgt
     7141 cctgttcttg taggtccctt cactttcctt caattgtcag actttgaaga aggcgtgaaa
     7201 gcagacgact tcgtagatag cttagtggct gcttaccaag aagtttttgc taaattggct
     7261 gaacttggtg cgactcgcat ccaattggat gaagcggctc ttgtaaaaga cttgacagct
     7321 gaagaaaaag ctctcttctt gaacctttac aacaaactct tggctgacaa aaaaggtctt
     7381 gaagtcttgc ttcaaactta tttcggtgat gttcgtgacg tatacgctga ccttgtaaac
     7441 ttaccagtag atgctatcgg tcttgacttt gttgaaggta agaaaactct tgaactcgtt
     7501 aaaggtggct tcccagctga caagactctc tatgtaggta ttgtcaatgg taaaaacatc
     7561 tggcgcaaca actacgaaaa gagcttggct gttcttgagc aaatcccagc tgaaaacatc
     7621 gttttgacaa gctcttgctc acttcttcat gtgccattta caactgctaa tgaagaattt
     7681 gaaccagcac tcttgaacca ctttgccttt gcagttgaaa aattggatga aatccgtgac
     7741 ttggatgcta tccgcaatgg tcaaggttca gaagctcttg cagccaacaa agaactcttt
     7801 acgactgagc gtgttggtga aaatgctgaa cttcgtgcgc gtatcgctgg cttgacagac
     7861 gcagactaca ctcgtttgcc agtctttgca gaacgtgaag ctatccaaga agaagctttc
     7921 aaacttccag ctcttccaac aacaacgatt ggttcattcc ctcaaacaaa agaagttcgt
     7981 gccaaacgtt tggcttaccg taaaggtgaa ttgtctcaaa aagagtacga tgctttcctt
     8041 gctgaaacga ttgacgaatg gatcaagtgg caagaagata ttgactttga tgtccttgtt
     8101 cacggtgaat ttgagcgtaa tgacatggtt gagtacttcg gtcaaaactt gtcaggatac
     8161 ctcttctcta aaaatggttg ggtacagtca tacggtatgc gtggggtgaa accaccaatc
     8221 atctggggtg atgtcactcg tcttaaccct atcactgtta aatggtctag ctatgcacaa
     8281 agccgtacaa acaaacctgt taaaggtatg ttgactggac ctgttaccat cctcaactgg
     8341 tcattcccac gtgaagacat ctctatcaag gattcaactc ttcaaatcgc ccttgctatc
     8401 aaggatgaag tgcttgacct tgaagctgct ggtgtgaaaa tcatccaaat tgatgaggct
     8461 gctcttcgtg aaaaattgcc actccgccgt agcgactggt acgaagacta ccttgactgg
     8521 gctattcctg ccttccgctt ggtacactca acagtagcgc cagacacaca aatccacact
     8581 cacatgtgtt actcagaatt tacagatatc atcccagcta tcgataacat ggatgcagac
     8641 gttatttcct ttgaagctag ccgttcaaac cttgaaatct tggacgaact caaagcgaaa
     8701 aacttccaaa cagaagtggg acctggggtt tacgatatcc actcacctcg tgtaccaaat
     8761 gaaggcgaaa tcgacaacac aatcgaagcc atccttgcta aagtgccaag caagaaagtt
     8821 tggatcaacc ctgactgtgg tttgaaaaca cgtggtatcc cagaaacaaa agaaagcttg
     8881 atccgccttg ttgaagcagc taaagctgcg cgtgagaaat tgtaagattg gatttctctc
     8941 catacagtgg ttgttcaaaa agaaatcaac tagaaaaggt tattacatat gtcacgccaa
     9001 acaccgtcac tctcatttga agtgttccct ccaaacccag ccgtgggtaa tgataacatt
     9061 atttcagcct tgcaggatat gcaggagttg gttccccatt ttatcagtgt aactgccagc
     9121 aataataaat ttaatatcaa ggaaacgacg gttcgtttgg ctgactttat ccaaaatgat
     9181 ttggcgattc cgaccattgc ccacttgcca gctatttatc taactaagga caaggttgct
     9241 gaaactattg ctgacttgga caaagttggg gtgcagaaaa tcttggctct tcgtggggat
     9301 attattccag acgtggaacc acaaaaggat ttccgctatg caaccgactt gattgagttt
     9361 atcaaggaac gagcccctca ctttgatatt attggagctt gctatccaga agggcatcca
     9421 gattcgccaa atcagatttc agatattcaa aatcttaaga agaaagtgga tgcaggctgt
     9481 tcgagcctcg taactcagct cttctttgac aatgagcgct tctatgattt tcaggacaag
     9541 tgtatcttgg ctgggattga tgttcccatt catgcaggaa ttatgccaat tctgaatcga
     9601 aatcaggctc tccgactctt gaagacttgt gagaatatcc atcttccacg caaatttaaa
     9661 gccatcttag acaagtatga gcatgaccct gagtcgctca gagcagcagg acttgcctat
     9721 gcagtggacc aaatcgtgga cttggtaact caggatgttg ccggtgtgca tctctatacg
     9781 atgaataatg ctgatacagc aaaatacatc catcaagcaa cccatgcctt gtttaatcac
     9841 cagtctctag gataataaaa gcaaaccatt cttctcaggt gaggggaatg gttccttttt
     9901 aatggtaaag acctcacttt ttaagaaaaa tatgataaaa taaattctgt acgtacttga
     9961 tacaaagatg aaggtattaa ataatacaat gcatttaaac tgtaagattt aacgacacga
    10021 gtgagtcaaa tcgatgttat ttgacgagag agttagtaaa gcatttagct aatcgcccga
    10081 tagcgattag cgtgaaagct ttagatactt tagtattaaa cctttctaat gatgtatctt
    10141 gaaaactgaa cttgcctaca actctgtgga aaaagataaa tctccctagg agtagtcgct
    10201 ccgtcgttcg atttcctatc ttcctttgag ttgcttgacg gcttggtatc ttgatgactt
    10261 gaattttggt ctcatttctt aggaaaaaag ataagcttcc tagcactcgt cgagtgtgac
    10321 gtcaccttcc tatttttcta cagaaatgtt cggcaagccg aaccgtccaa aatatcttgt
    10381 gtaattgaac acggccgaaa agctgtgtaa aaaagataaa ctgtcttgtc ttcatcgaag
    10441 acttcgtcag tttcctattt ttactttgct tttgacgtcc ttggtatctt gatctttgta
    10501 ggcaaggcgt ataatttcat caatccaaag gggattaaaa tggcaaaaca agtgtttcaa
    10561 acgacttttg cgggtcgtga gttaattgta gaaactggtc aggttgctaa gcaagcaaat
    10621 ggctctgttg tcgtacgtta cggtgagtca actgtcttga ctgctgccgt tatgtctaag
    10681 aaaatggcaa ctggggattt cttcccactc caagtcaact acgaagaaaa aatgtatgcg
    10741 gctgggaagt ttcctggtgg ctttatgaaa cgtgaaggac gtccttcaac agatgcgacc
    10801 ttgacagcgc gtttgattga ccgtccgatt cgtcctatgt ttgcggaagg tttccgtaat
    10861 gaagtccaag tcatcaatac agtgctttct tatgatgaaa atgcatctgc accaatggct
    10921 gctatgtttg gttcatcttt ggcactgtct atttcagata ttccatttga cggaccaatt
    10981 gctggggtac aagtgggata tgtagatggc caaatcatca tcaacccaag tcaagaacaa
    11041 gcagagcaat ctcttcttga attgacagta gctggaacca agcacgctat caacatggta
    11101 gagtctggtg ccaaagaatt gtcagaagaa atcatgttgg aagcgcttct taaagggcac
    11161 gaagctgtca aagaattgat tgccttccaa gaagaaatcg ttgctgctgt cggtaaagaa
    11221 aaagcagaag tggaattgct tcacgtggat gctgaattgc aagctgaaat cattgcagcc
    11281 tacaacagtg acctccaaaa ggcagttcaa gtagaagaga aattggcccg tgaagctgca
    11341 actcaagcag tgaaagacca agtgactgcc gtttacgaag aaaaatatgc gaaccacgaa
    11401 gaatttgacc gtattatgcg tgatgtggct gaaatcttgg aacaaatgga acacgcagaa
    11461 gtgcgacgtt taattacaga agacaaggtg cgtcctgatg gtcgtaaggt cgatgaaatc
    11521 cgtcctttgg atgcggttgt tgacttcctt cctcgtgtac atggttcagg tctctttact
    11581 cgtgggcaaa ctcaagctct ttcagtcttg accttggctc cgatgggaga aactcaaatc
    11641 attgatggtt tggatccaga gtacaagaaa cgctttatgc accactataa cttccctcaa
    11701 tattctgtag gggaaacagg tcgttacggt gcgccaggtc gtcgtgaaat cggtcacggt
    11761 gcccttggtg agcgtgctct tgctcaagtc ttgccaagct tggaagaatt cccatacgct
    11821 atccgtctag tagcagaagt tttggaatca aacggttctt catctcaagc ttctatctgt
    11881 gcgggaactc ttgcccttat gactggtggt gtgccaatca aggcgccagt agctggtatt
    11941 gctatgggac ttatctcaga tggaaataac tacacagtat tgacagatat ccaaggtttg
    12001 gaagatcact ttggagatat ggacttcaag gttgcaggta ctcgtgatgg gattacagcc
    12061 cttcaaatgg atatcaagat tcaagggatt actgcagaaa tcttgacgga ggctcttgct
    12121 caagccaaga aagcgcgttt tgaaatcctt gatgtcattg aagcaaccat tccagaagtt
    12181 cgtccagaat tggctccaac tgctccgaaa attgatacga tcaagattga tgtggacaag
    12241 attaagattg tcatcggtaa gggtggagaa accatcgaca agattatcgc tgaaacaggt
    12301 gttaagattg atatagacga agaaggaaat gtgtctatct actctagtga ccaagatgct
    12361 attaaccgtg ccaaagaaat tattgctggt ttggttcgtg aagccaaagt ggatgaagtt
    12421 taccgtgcta aagtcgttcg tatcgagaaa tttggtgcct ttgttaacct ctttgataag
    12481 acagatgccc ttgttcatat ctctgagatg gcttggactc gtaccaatcg tgtagaggat
    12541 ttggtagaaa tcggggatga agttgatgtt aaggttatca agattgatga aaaaggccgt
    12601 atcgatgcct ctatgaaggc tcttctacct cgtccgccaa aacctgagca tgatgaaaaa
    12661 ggtgaaaagt ctgagcgccc tcaccgccca cgtcatcaca aggatcacaa acctaagaaa
    12721 gaatttacag aaacaccaaa agattcagag taagaaaagg agaaatgtat ggggtggtgg
    12781 cacgaaacca ttgatatcgt aaaagaaaat gatccagcgg cccgcaccac tttggaggtt
    12841 ttgctgactt atccaggtgt caaggccttg gcggcccacc gtctctcgca ttttctctgg
    12901 aagtacgact tcaaactctt agctcgtatg cacagtcagt tttggcgctt ttggactcag
    12961 attgagattc atccaggagc ccagattgat tcaggtgtct ttattgacca tggttctggt
    13021 ctggtgattg gagagacagc gattgttgaa aaaggcgttc ttctctatca cggagtgact
    13081 ctcgggggaa cagggaaaga ctgtggcaaa cgccatccga ctgtacgaaa gggagccctc
    13141 atatcagccc atgcccaagt tatcgggcct gtggaaattg gtgaaaatgc caaggtcggt
    13201 gctgcagcag ttgtcgtagc agatgtacct agtgatgtga cggttgtcgg tattccggcc
    13261 aagattgtcc gtcttcatgg taagaaagat gagcctgtta ttcacgaagt cgaagaaaaa
    13321 cgggagtatt atgtcaataa actcgagcag gctaaagatg ccagtcacag atcgtctggt
    13381 ttgtagagga tacctatatg attcaagcaa gaaacaagtt aagccaagag gagctatctg
    13441 aggcgaaaaa agtaattaac tgttgccaaa actatgacgg tacctatcgc gatccctatc
    13501 tctctaacat gcttaatttt gacccaaaca tgcccgcctt tttcctttat tatgaaaaag
    13561 gcaaacttgt tggtttatta actgtctatg cagatgacca agatgtagaa gtgacgatat
    13621 tggttcatcc aggtcatcgc cgtcagggga ttgcgcgtgc attgtttact agttttgaga
    13681 gagaaacagc ttctttcccc attcggtcag tcacttttca gacagaacgt atttttttag
    13741 agaatcatcc tgactttgcc agtaactggg gactaatcga ggatgaagag acagaaactt
    13801 ggttaggtaa ggatagaaga ccttatccgt tagcaaatgt ttcccatctt gaagttttgt
    13861 tagcagatag ttcgtatcag gatcaaatta gtcaattaaa atttcaggca ttttcagagg
    13921 aacatgaatc gagagaagtt gtggatagat atgtcgctga agctctgaag gatccagaaa
    13981 gtcgcttata tattttgtta aaagacggtc aggttattgg gacttgcacg gtagatttat
    14041 cgactaatac gaattacttc tacggtttag caatatcgga acctgaacgt gggaaaggct
    14101 atggaagcta cttagcaaaa tccctcgtca accaactaat tgagcaaaat gacaaggaat
    14161 ttcagattgc agtggaagat agcaatgtag gtgccaaacg tttgtatgaa aaaattggct
    14221 ttgtcaaaca gacacaggtg gtttatctga atgagaaagg agcaagggat tccgaagtgt
    14281 agagacattc ggactgaaat ttacttgagc tcttagttta gtgatgaaac taacagttct
    14341 tggattttag ctttcctgat tatgatttat gattaaaatc tatgacacca tgtctcgtga
    14401 tttgcgagaa tttgtcccga ttgaggacgg caagatcaag atgtatgttt gtgggccaac
    14461 cgtgtacaac tatattcacg tgggaaacgc ccgttcgacg gtagcttttg atacgattcg
    14521 tcgctatttt gagtaccgtg ggtataaggt tgcctatatt tccaatttta cagatgtgga
    14581 tgataagatt atcaaccgtg ccagggaaga aggcatcaca cctcaggagg ttgcggataa
    14641 gtacatcgct gcctttcgtg aggatgtgac ggccttaggc gtgaaacctg cgactcgcca
    14701 tccgcgtgta gtggagttta tggcagacat catccgtttt gtggaagact tgatcgagaa
    14761 aggctttgcc tatgagagtc aaggggatgt ctatttccgt gtagaaaaat cccacaacta
    14821 tgctaaattg gctaataaaa ccttggaaga tttggagcta ggtgcttcag gtcgtaccga
    14881 tgaagaaacg gctcgtaagg aaaatcctgt agattttgct ctatggaaat cttccaaacc
    14941 aggtgagatt tcttgggata gtccttgggg acctggacgt ccgggttggc atattgagtg
    15001 ttcagtcatg tcgacagaga ttttaggtga taccattgat atccacggtg gtggagctga
    15061 cctagagttt ccacaccaca ccaatgaaat tgcccaatct gaagctaaaa caggcaaggc
    15121 ttttgctaac tactggatgc acaatggctt tgtcaatatc gacaatgtca aaatgtctaa
    15181 gtccttgggt aacttcatta cggtacacga tgcccttaaa actcttgatg ggcaagtact
    15241 tcgtttcttc tttgcgaccc agcactaccg taagcctatc aacttcacgg aaaaggcagt
    15301 tcgcgatgcc gagaccaatc tcaagtatct gaagaatact tacgaacaac catttacagg
    15361 aaacgtggat gcccaagagt tacaaaactt taaagataag tttgtagcag ctatggatga
    15421 agattttaat gctgccaacg gtatcacagt tgtctttgaa atggccaaat ggatcaactc
    15481 agggaactat gatgcaagtg tcaagcaagc tcttgcagat atgttagaaa tttttggaat
    15541 tgtctttgtt gaggaagttt tggatgcaga gattgaagac ttgattcaaa aacgccaaga
    15601 ggcgcgtgcc aatcgagact ttgagacagc agaccaaatc cgtgaccaat tggttactca
    15661 aggaattaag ctccttgata ccaaggatgg agtgaggtgg acacgtgatt gatgtcaatc
    15721 tcattaacgg gattgcgcta gcctttgagg gggatgcggt gtattctatg tatattcgcc
    15781 gtcacctcat cctcaaaggt atgaccaaac ccaataaact ccatcaagaa gcaaccaagt
    15841 atgtgtcagc caaggctcag gctcgcctga ttgctctcat gttggaggag caggtcctaa
    15901 cggaaaaaga agaagaaatc tacaaacgtg gccgcaatac caatagccac acaaaggcta
    15961 aaaatgcaga tgtcgtgact tatcgtatgt ccacgggatt tgaagcggtt atgggctatc
    16021 tccatatgac tgagaatctg gaacgtcttg agagtttggt ttcatggtgc atccaaaaag
    16081 tggagggcta gaacatgagg gaaaaagaac tacaagactg gtttcctgag gctcggattt
    16141 cagaccaacc agtagagaaa gagggctatc tcacgctccc tttagcttct cagcagtgga
    16201 ttttgctgga ggaagctggg ctcagcgagc gtgaaaagca gttggttgcc cttttgaccc
    16261 agcaggagca ggctcgttcg ctaaaccctt ggtattccta tctggttgaa ggcaagggac
    16321 aggcaccgca agtttttaaa aagattcagt tggtttattg ccatctttct tattttcagc
    16381 aggaaaatct ggcttcttgg ctagatatga tgcggactct ttttccgaat tgtcagacag
    16441 tgctacaggt cggagctcag gattatgttt tcgtgcttca acaagacaaa tacacttctg
    16501 taagagatat tttaagtgat acgattgaag cggttgagta tgactttgga cttcgtcttt
    16561 ctatcatgtt gggtcaggtt tggtctcaga caggacatca agccctatca gacttaatca
    16621 aagctgagcg ggatttgttc aagacatggt ggcgtcaggg tcaccaaggt gttcatactt
    16681 tttctcagct ctatctttgg agtatgggag aaagactcgt ggacttgaag ccaattaaag
    16741 aatgtctaca ccagatgatt ttggatcaag atcagattca ggaaatcatt ctctctcttt
    16801 gggaaaatag tgctgttctc actaaaacag cccagcaact ctatctgcac cgcaattctc
    16861 tccaatacaa gattgataaa tgggaagagt tgacagggct tcagttgaaa gagttgaccg
    16921 acctgacctt gtgttatcaa ttgattttag gttctttgtc aactatagtt ggtttgtaaa
    16981 gaagttaata tttggagaag aggattgcca tcttctccat tt
//
LOCUS       DAVKUR010000043        16801 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKUR010000043 DAVKUR010000000
VERSION     DAVKUR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.043"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1133
                     /locus_tag="VW749_001577"
                     /pseudo
     CDS             1..1133
                     /locus_tag="VW749_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VW749_001578"
     CDS             complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VW749_001578"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0175594.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3025..3723
                     /locus_tag="VW749_001579"
     CDS             3025..3723
                     /locus_tag="VW749_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0175595.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3766..4662)
                     /locus_tag="VW749_001580"
     CDS             complement(3766..4662)
                     /locus_tag="VW749_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0175596.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQTDIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4671..5606)
                     /locus_tag="VW749_001581"
     CDS             complement(4671..5606)
                     /locus_tag="VW749_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0175597.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5603..6328)
                     /locus_tag="VW749_001582"
     CDS             complement(5603..6328)
                     /locus_tag="VW749_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0175598.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(6412..7047)
                     /locus_tag="VW749_001583"
     CDS             complement(6412..7047)
                     /locus_tag="VW749_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0175599.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7049..7876)
                     /locus_tag="VW749_001584"
     CDS             complement(7049..7876)
                     /locus_tag="VW749_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0175600.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDIIQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7898..9215)
                     /locus_tag="VW749_001585"
                     /pseudo
     CDS             complement(7898..9215)
                     /locus_tag="VW749_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189734.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            9473..10084
                     /locus_tag="VW749_001586"
     CDS             9473..10084
                     /locus_tag="VW749_001586"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0175601.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10129..10857
                     /gene="rlmB"
                     /locus_tag="VW749_001587"
     CDS             10129..10857
                     /gene="rlmB"
                     /locus_tag="VW749_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0175602.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VW749_001588"
     CDS             complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VW749_001588"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0175603.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11873..12097)
                     /locus_tag="VW749_001589"
     CDS             complement(11873..12097)
                     /locus_tag="VW749_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0175604.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12175..12918)
                     /locus_tag="VW749_001590"
     CDS             complement(12175..12918)
                     /locus_tag="VW749_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0175605.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12918..13718)
                     /locus_tag="VW749_001591"
     CDS             complement(12918..13718)
                     /locus_tag="VW749_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0175606.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13876..14232)
                     /locus_tag="VW749_001592"
     CDS             complement(13876..14232)
                     /locus_tag="VW749_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0175607.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14226..14756)
                     /locus_tag="VW749_001593"
     CDS             complement(14226..14756)
                     /locus_tag="VW749_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0175608.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(14756..15250)
                     /locus_tag="VW749_001594"
     CDS             complement(14756..15250)
                     /locus_tag="VW749_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175609.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15385..15831
                     /locus_tag="VW749_001595"
     CDS             15385..15831
                     /locus_tag="VW749_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0175610.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15828..16475
                     /locus_tag="VW749_001596"
     CDS             15828..16475
                     /locus_tag="VW749_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0175611.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
BASE COUNT         5058 a         3790 c         2973 g         4980 t
ORIGIN      
        1 tctaaaattc cttatcttga aacgactggt atgccttcta gaattctcct tagaaaacgc
       61 cgtttcaagt gctatcactg ttcaaaaatg atggttgctg agactcccct ggtaaagaag
      121 aatcaccaaa tccctcgtat catcaaccaa aaaattgctc aaaagttaat tgaaaagatt
      181 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
      241 aatgattttc actttaaaca tgatttttcg cgtcttcctg agattatgtc ttgggatgag
      301 tatgctttta caaagggaaa gatgagcttc attgcgcaag attttgaaaa gctcgatatc
      361 atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct tcgctacgat
      421 agagttgtcc gatgtcgcgt caaaattatt actatggata tgtttagccc ttactatgac
      481 ttagctagac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc tcccagactg
      541 tttcactccc gaatgctaaa atcgttcttg atcgctttca cattgtgcaa catcttagcc
      601 gtgctatgag tcgtgtgcat gttcaaatca tgaatcagtt tcatcgaaaa tcccatgaat
      661 acaaggctat caagcgctac tggaagctca tacaacagga tagccgtaaa ctgagtgata
      721 agcgttttta tcgtcctact tttcgtatgc atttaaccaa taaagagatt ttagacaagc
      781 ttttgagcta ttcggaagac ttgaaacacc actatcagct ctatcagctc ttgctttttc
      841 acttccagaa taaggaacca gagaaatttt tcggacttat tgaggacaat ctgaagcagg
      901 ttcatcctat ttttcagact gtctttaaaa ccttcctcaa agataaagaa aagattatca
      961 acgcccttca actaccctat tcaaacgcca aattggaagc gaccaataat ctcatcaaac
     1021 ttatcaagca caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta
     1081 tcgctctgaa tatcaaaaaa gaaaggacga aatttgtcct ttctcgatct tagcttttct
     1141 tcaacccact acagttgaca aagagcctga aaactacggt ctaatttttt gtccaaatgt
     1201 aaaccacttg gaactattat tcaatttatt ctttttagca aatgttcccg ttttaatccc
     1261 agttacagtt tttaatcctt tgtaaccgtt gattttacaa agcttttaat ttttttgcga
     1321 ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga tacggttaac
     1381 atgatccact tcatttacga tacgtactga gattttttga agtacttccc atggaatttt
     1441 ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa tcgtgtagtc
     1501 atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa cagtgaagta
     1561 ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa tagcgtctga
     1621 ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga tagcaagtcc
     1681 tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct ctgtaccaag
     1741 agcacgaact tcatccttgt aaagagtatt gagtggttca atcaattcaa actgcatatc
     1801 ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga
     1861 ctcgataaca tctgtatata aagtaccttg agcaaggaat ttcacatctt tgagcttgct
     1921 tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt tttgttcagg
     1981 gtcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt
     2041 caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt tacgaagaag
     2101 accgtggtcc acgaagatac agatcaattg atcgccaatc gctttttgga gaagaacccc
     2161 aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat caccgacggt
     2221 ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt cacctttagc
     2281 cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag aatgacgaac
     2341 ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg
     2401 gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc
     2461 atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg atggtgtgtg
     2521 agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa caacttttcc
     2581 tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg gaattccgag
     2641 ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat ttggaccacc
     2701 tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa ttttatggct
     2761 ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct ggttgtactg
     2821 gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg aaatgttgct
     2881 catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca aataagggcg
     2941 aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt acaatagaga
     3001 aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca tgatcagata
     3061 aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag tgaaagagat
     3121 ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc tctattagtc
     3181 gaagaaggcg tcttagagcg ccatgtagga agcggcacct ttgtttccag tactcgagta
     3241 caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca aggtaaagtt
     3301 ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga agttgccaag
     3361 ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta tgccgaccaa
     3421 gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa
     3481 gaagaaatca ccagtcattt cttccaaacc ttgcaaaaac atggctatcg tatcggcaaa
     3541 tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta tttggaagtt
     3601 gaaaaaggac atgctattct tggattgacc caggtttcct acctagaaga tggtactgct
     3661 tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct tgaaaataat
     3721 tagattacca cgcaaaaact ctctgtcacg gacaaagagt cttttttatt tttctaagaa
     3781 taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac caagaaaatc
     3841 aatgggataa aattgttcat tcattattaa gaaggcaaag aaaatcgccg atattggctc
     3901 aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt taaggaaagc
     3961 tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga gaaaatcaag
     4021 actagtcggg atatcggtct gtagaacccc tgtaaaagga agggcgacca aacctgctat
     4081 gaccattccc acaccaatga ccaagctgct cccccacttt ttaatcaagg ctatgggtaa
     4141 aatgatatac agagcataag tcaaggcaga aaagagaccc cagaacagac cagcaggtgt
     4201 catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa
     4261 tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac agctataaat
     4321 taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat tggtctcctg
     4381 aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa aaataagaag
     4441 agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg cagtagcata
     4501 agccaagagc atgagaattc caccagcgat taaaagacgc aagttggtca agaccagagc
     4561 cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc aagcaatacc
     4621 agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc ttactcttct
     4681 ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct ctcgtccttt
     4741 tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt ccacatgata
     4801 aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca tgctaaagaa
     4861 cgttccttgt catccaaagg agaaaaattt tgacttaagt ctcttgcaaa atcatctgct
     4921 aaatagtgtt ctaaaaagat ttgtaaatcc tttatagtcg aaaataaacc agcgctccca
     4981 gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc tacacctcta
     5041 actgttggaa cagcaagctc aactggccca aacttggttt ccgtcattcc ccaaggtttc
     5101 cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc caaaataaag
     5161 cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg tctgttgaga
     5221 tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg aataaaagga
     5281 tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata atcactctca
     5341 ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca caagaaggta
     5401 caaactgtgc caaccccaac aaccttgctg acactagcta ggtcataaac tagtcctgcc
     5461 tcagtctgca agccatgctc tgggtcactc tggcctaaat agaactctgt ccattgattg
     5521 tccttaaaat acgcaaaaga ggctccggga taaattcctg cctcgatttg ttcttctatt
     5581 tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca ttatttctat
     5641 ctttacaaag gaagaatttt tcagacttag gaataaaata ttcagtagac tcaaacttct
     5701 ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat aagtcccagg
     5761 taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca agggatgccc
     5821 caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat tccatagaaa
     5881 tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc ttttctccta
     5941 cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca tcttctggtg
     6001 agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc gaatctgttt
     6061 tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat ctagctagtt
     6121 tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa accagctttt
     6181 caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag gccttcattc
     6241 caagggtttc aatataaaat gtttcattta attttctatt attagctttt aaagtaggaa
     6301 taatccgtac aatctgattt acattcataa attcctccgt cactttttat tttaaaggat
     6361 tttagaattt tttacaagat attatgctca aatttaacat tatttagcta tttagtaaag
     6421 atagtctttc aaggcttttg acaaagcctg ataaccagca atactgaggt gcagtccatc
     6481 agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa atactggcac
     6541 aaattccacc tgcatatagg cagatgcaag ctcttgatag gcttgattcc agttctgaat
     6601 tttttcattc gagcggatat agactgcctg ctggtactcc tctccctcat tgacaggcaa
     6661 aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc
     6721 ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat ttgtcccaat
     6781 cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaagat tctctagtaa
     6841 cagtcctgtc tgatagccac gaattcctcg attgacaatc gtctttgaag tcccaaatag
     6901 ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt ttggttctac
     6961 aacagaaatg tgatttaggt gacgatactt agtttgaatt ttttcttgtt cctttaggag
     7021 ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag ttttccaaga
     7081 cttgataaac tcctccttgg ctgttggctg gtgctagagc agtcgccaca gctttggctt
     7141 tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt tcaacatcat
     7201 tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc ttgagtaatt
     7261 cctccaagcc ccatgcttta tgaatcccag cttggatgat atcaatgcaa ccatagccac
     7321 tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa accgaactca
     7381 aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg tcagatgtta
     7441 attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga gtcataaaac
     7501 tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc cccgttacaa
     7561 caaactggtc ctgacacgct cgaaccttga aatgagtcaa agccttgttg acaatggcgt
     7621 catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg ccattagcaa
     7681 caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg tgaatttcat
     7741 tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa atcttttcca
     7801 atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata tctgtcgcaa
     7861 ttaccttaat catcatttac tttcctctgg attcaagcta ataccacttc aatcccacat
     7921 gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca tctaactggt
     7981 cacgatgact gccatcctct ataaaatctt ccaaaatata agtttggtaa tgatacaagg
     8041 gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta ggatgatctt
     8101 tagctgttcc gatagttgtt tttccatcat tcttcttgat ggtgacatcc atgagaacac
     8161 cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaattcgt tgattggaaa
     8221 tgaagttccc cattgaatag ataatgagtt tcttatctcc atctttttca accgtttcag
     8281 atggttcaac aacgtgagga tgccctccaa agataatatc cgctccccaa tcgatcatct
     8341 tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca cccatctgag
     8401 gcatgataat ggtgatatct gcttccttct ctgcccgttc aacttcagcc ttcatcttat
     8461 cttcgtttaa atctaaaaga taacgattat agtcttcctg agaaatatac tgctcaattc
     8521 cattgaaacc ataggaatag gctgacaatg caaccttgat accattcact tccttaatga
     8581 ccagcggaac ctgatcacgt ggttcgtgcg tataaactcc gattggagtg attccagctt
     8641 tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa atatgattat
     8701 gagctaaatc cagcacatga taacctgcct ccttaatagc atccataact tcagcaggag
     8761 cattaaagag aggataaccc gctaaataat gatccttatt aatggtttct tcaaaatcac
     8821 caatagctaa atctgcttgc ttgaaccaag gagtcacata ctcaaaattt tcatgaaagt
     8881 cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc
     8941 cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt tgcttagttc
     9001 cctcttgaga aatagtatct cgtttttgac tagtaaagag attccttgga agctttcaaa
     9061 caacaagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca caaatccctt
     9121 attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa acgaaaagct
     9181 aaaccaccct gatttcgatt ttgtcttctt tgcatcttca ttctccctac tttcttatgc
     9241 aagccttttc tttttattat atcacagata agtatttctt tcacaattga attgaacttc
     9301 ccatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc attttgtgat
     9361 atcatgtaga ggtaatgaaa ggaaatgaac taatccacag tggcttattc caagtatacc
     9421 acttgggctt tggcagtagt taactgcact aaacataata taaggagaga aaatgtctgc
     9481 aatagaacgt attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg
     9541 gaatcctact ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat
     9601 catcctaggc gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga
     9661 aaaaatggga ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg
     9721 cattatcgct gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta
     9781 cgatttggaa ggcattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc
     9841 tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg
     9901 ccatgcccgc gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact
     9961 caaaggctac aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt
    10021 ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga
    10081 ataaagaaaa tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat
    10141 gatattgtct atggtgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa
    10201 ctctacctcc aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca
    10261 gaaaagaagg tgtccatttc ttggacatca aaaaaaaatc tctctgagat gactgaaggt
    10321 gctgttcatc aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac
    10381 atccttgcaa aaacacgcca agaagaaaat tcacttctat tgattctaga tggtctaacc
    10441 gatccccata atctgggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc
    10501 atcattccca agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt
    10561 gctattgaac acgttccaat tgcccgagta accaacctca gtcaaacctt agataaactc
    10621 aaggatgaag gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg
    10681 aatacaaaag ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac
    10741 ataaaaaaac aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt
    10801 aatgccagtg ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa
    10861 agtttccagt catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta
    10921 taggcttctt gaccagcgat agctccatct ccaactgctg ttgttacttg gcgaaggtct
    10981 ttcaagcgaa catctccaac tgcaaagata ccgtcgactg cagtcttcat gtggctatct
    11041 gtcacaatcc agcctgcctg atcttggata ttcaattctt taacaaaatc gctaagaggg
    11101 tccaaaccaa catagataaa gacaccaccg aaggcttgct ctgtcacttg acctgttttc
    11161 acattttcaa aaacgacaga ttctactctg ttttcaccct tgattttcct tactacagaa
    11221 tcccatataa agctgatttt ctcattggca aaggcgcgat cttgtaaaac cttttgggca
    11281 cgaagttggt cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg
    11341 gcttcttcaa cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa
    11401 gcaccatcac acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggc
    11461 actcccaaag gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt
    11521 tggtcatcag tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca
    11581 taaatgtgct caacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt
    11641 ccactaatat tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca
    11701 cctggcagac caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc
    11761 gcagtcatcc ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct
    11821 ttcttgttgt aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct
    11881 tgaaaacaag aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa
    11941 tcataatcat atcatagaga tgggcttggc gagccttggc tgtcttatca actcccgaca
    12001 tggctctcag accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca
    12061 aactctcgaa atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt
    12121 ttaaagagta aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat
    12181 ataagtccgt ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat
    12241 aatctcatcc ggagttccag actcgatgat tttcccctta tctaagaaga gaatcttatc
    12301 cgcaacttgg gctacaaagg acatgtcatg actgaccaaa atcatggtct gacctgactt
    12361 agcagcatct gcaatagact tttctacttc accgaccaat tctgggtcaa gggctgaagt
    12421 tggttcgtct aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg
    12481 ttgcttctgt ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac
    12541 cttagccaac tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac
    12601 aaccaagcct tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg
    12661 gaaaaccata gacaacttac ggcgtagggc aaggatttct tcttgagtga ttttagaaaa
    12721 atcaactgaa aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag
    12781 actgcgaaga aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc
    12841 tttttgaata tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa
    12901 attcgaaatc ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt
    12961 gcagaaatag ccatttttct ctcgatgaaa cgaccgagac tttcaattcc gatattgact
    13021 acccaataaa caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct
    13081 agaatctgag cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc
    13141 ttggtcaaac cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga
    13201 ataatcactc gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc
    13261 tcaccaggat taactgagag aatggctgca cgaatggttt cactagcata agctgcctca
    13321 ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca
    13381 gttccccatt gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg
    13441 agttgcacca aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat
    13501 aaaatcttga cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa
    13561 agggcaccac caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt
    13621 ccatcaaaga ccgaacgtag gctaaacagc ttgccattcg gaatcaattg catcaagttt
    13681 tggtaccaat ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat
    13741 gattcattct accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact
    13801 ttgtctacct actagtttat catactttga aacagggaag ttatatattt tatctatcaa
    13861 agagatagat aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg
    13921 cttaacggtt ccattttcta ctaaaatggg ccgttttaac aacataccgt cacttgctag
    13981 caactcagcc gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg
    14041 gtatttgata ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca
    14101 attcaaaatg acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac
    14161 acctaattga tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat
    14221 aaattctaac atgtgcttct ccttctattg cttctatctt taaaatctac tccttcatgc
    14281 tccaagagcc aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct
    14341 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    14401 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    14461 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    14521 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    14581 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    14641 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    14701 agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt ttgcattatt
    14761 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    14821 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    14881 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    14941 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt
    15001 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    15061 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    15121 taataacatc tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac
    15181 attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    15241 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    15301 atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca
    15361 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    15421 attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    15481 cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa
    15541 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    15601 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    15661 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    15721 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    15781 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    15841 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    15901 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    15961 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    16021 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    16081 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    16141 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    16201 ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt
    16261 acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    16321 ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt
    16381 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta actgcgtccg
    16441 tacttcaata catcgctatt gtttattaca tgtaaaactc tcagtaggca gagcctgctt
    16501 agagttttac aaacgaattt cccaaagagg aagcaatatg aaagcagtca ttgcttgtgt
    16561 tcataaaatt ctcagaatca tttacaaact actctccacc aagtagactt atcaaaaaga
    16621 aaaggcgcta ggactgaaga aacagttcta acgcccaaat taaaaaaatt tcaactacag
    16681 tatagcacag gaaatgattt tttgcgcttt tttactgttt tttcaaataa aaaaagacaa
    16741 agttttatcc ttgtctttta gttttagtat tgctttggtt tcaatgtcaa taagtgtgtt
    16801 c
//
LOCUS       DAVKUR010000044        15238 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKUR010000044 DAVKUR010000000
VERSION     DAVKUR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.044"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..461
                     /locus_tag="VW749_001597"
                     /pseudo
     CDS             19..461
                     /locus_tag="VW749_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826702.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            499..801
                     /locus_tag="VW749_001598"
     CDS             499..801
                     /locus_tag="VW749_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0175612.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            809..1610
                     /locus_tag="VW749_001599"
                     /pseudo
     CDS             809..1610
                     /locus_tag="VW749_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1659..2123
                     /locus_tag="VW749_001600"
     CDS             1659..2123
                     /locus_tag="VW749_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0175613.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2280..2705
                     /gene="lacA"
                     /locus_tag="VW749_001601"
     CDS             2280..2705
                     /gene="lacA"
                     /locus_tag="VW749_001601"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0175614.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2736..3251
                     /gene="lacB"
                     /locus_tag="VW749_001602"
     CDS             2736..3251
                     /gene="lacB"
                     /locus_tag="VW749_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0175615.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3262..4191
                     /locus_tag="VW749_001603"
     CDS             3262..4191
                     /locus_tag="VW749_001603"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0175616.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4193..5173
                     /gene="lacD"
                     /locus_tag="VW749_001604"
     CDS             4193..5173
                     /gene="lacD"
                     /locus_tag="VW749_001604"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0175617.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5407..6243
                     /locus_tag="VW749_001605"
     CDS             5407..6243
                     /locus_tag="VW749_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0175618.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6279..6596
                     /locus_tag="VW749_001606"
     CDS             6279..6596
                     /locus_tag="VW749_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0175619.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6598..8292
                     /locus_tag="VW749_001607"
     CDS             6598..8292
                     /locus_tag="VW749_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0175620.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8501..9907
                     /gene="lacG"
                     /locus_tag="VW749_001608"
     CDS             8501..9907
                     /gene="lacG"
                     /locus_tag="VW749_001608"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0175621.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9997..10209
                     /locus_tag="VW749_001609"
     CDS             9997..10209
                     /locus_tag="VW749_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0175622.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(10488..11249)
                     /locus_tag="VW749_001610"
     CDS             complement(10488..11249)
                     /locus_tag="VW749_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0175623.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11537..12499)
                     /gene="nrdF"
                     /locus_tag="VW749_001611"
     CDS             complement(11537..12499)
                     /gene="nrdF"
                     /locus_tag="VW749_001611"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0175624.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12687..14846)
                     /gene="nrdE"
                     /locus_tag="VW749_001612"
     CDS             complement(12687..14846)
                     /gene="nrdE"
                     /locus_tag="VW749_001612"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0175625.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14927..15145)
                     /gene="nrdH"
                     /locus_tag="VW749_001613"
     CDS             complement(14927..15145)
                     /gene="nrdH"
                     /locus_tag="VW749_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0175626.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
BASE COUNT         4787 a         2654 c         3117 g         4680 t
ORIGIN      
        1 ttctttgaca aaaaccttgt gttttgctta gaagcggata atcaagaata actctttgat
       61 caggtagcaa gcttgttgga ggaacgagaa attgtaactc caacttatcg tgaagctttg
      121 atcacgcgtg aaaagtcatt tccaactggt ttagatatgg aatttctagg aaaggacttg
      181 caaatgtaat gattcctcac acagatattg ttcataatct agctgagaaa gtggtggttg
      241 ttcgattaga gaaaccggtg actttccata atatgattgc gccaggtaag gaagtagaag
      301 tatccttgct cttctttatc atcaataatt caagttcaag tcaaacgaac attcttgctc
      361 agttgatgga ctttttcaca ggaaatggac atcttgaaga cctatcaaaa atttccgaac
      421 cagaaaaact ttatgcttat atagatgaag caatcgctta atcttgtcta ttaaaaaata
      481 aaatcggagg aagtctatat gattaaaatt cttgctgcct gcggtgcagg tgttaactca
      541 agtcaccaaa ttaaaagtgc tctagaagaa gaactttcaa accgtggtta cgatgttcac
      601 tgtgatgcag ttatggtgaa agatgtaaac gaagacctta tgaaaggtta cgatatcttt
      661 acaccaatcg ctgcaacaga ccttggtttt gaaccaggta tcccagttat cgaagctggg
      721 ccaatcttat tccgtatccc agcaatgagc gttccagtat ttgacaatat tagacttcct
      781 gcgaaacaaa atatggtata gtagttctat gaatgatgaa gcaagtaaac aactaactga
      841 tgcacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga tgttagctgt
      901 attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct
      961 agaagacctt cttatggcca ctcttcaata gtgcgagaat atcgaactta tgaacaaatt
     1021 gcggctgatt ttggtattca cgaaagcaac tttatccgtc ggagccaatg ggttgaagta
     1081 actcttgttc aaagtggtgt tacggtttca agaactcctc tcagctctga ggacacggta
     1141 atgattgatg cgacggaagt acaaatcaat cgccctaaaa aagaattagc gaatgattct
     1201 ggtaaaaaga aatgccacgc tatgaaggct caagcgattg tcacaagtca agggagattg
     1261 tttctttgga tatcactgtg aactattgtc atgatatgaa gttgttcaaa atgagtcgca
     1321 gaaatatcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg ctcatgaaga
     1381 tatatcctca agtacaaact ccacgtaaat ccagcaaact caagccgcta acagttgaag
     1441 ataaaaccta taaccatgcg ctatctaagg agagaagcaa ggttgagaac atctttgcca
     1501 aagtaaaaac gtttaaaatg atttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat
     1561 tacgaatgaa tttgattgct ggcattatca atcatgaact aggattctag ttttgcagga
     1621 agtctaataa agaaactagc aaggtcaggc cttactttat tggtggacat ccaggattta
     1681 attgtcctct acttgatgat gaagtctatg aagattatta tctagagttt gagaaagaag
     1741 agacttgctc tgttccacgt cctttcccag aaacaggtat gttggatttc caagatagaa
     1801 gtccatggct agagggacaa aaagaaatag atcttagtta tgatcttttc agcaaagatg
     1861 cagtgacttt ggatgaattg caatctcgaa caattgccct tcgttctctt aaacatgata
     1921 ggggattgaa agtgcatttt gcagaatttc caaacctcat catctggtca actttgaaca
     1981 agggaccttt cattaccttt gaaccatggt ctggcttgtc aacattcctt gaagaaggag
     2041 atcatttaga agataagaag aatgtttgtc tcttagaagc caatcaggtt gaagaattag
     2101 ggtttgagat agaagtttta taaaaaagta aaaaataaat aacaaaaaca aacacaaact
     2161 gttgacttct tcaaacaata gtagtatatt atgtttgtga ggactaattg actgtttttt
     2221 aaagacagcc aatacactgc tggaatccag catagaaaaa ataaaaagga gtatacaata
     2281 tgtctattgt tatcggtgca gatgctgcag gtttgagatt gaaagaagtt gtgaaagact
     2341 tcttagaaaa agaaaacttc caccttgtgg atgttacagc tgaaggtcaa gactttgttg
     2401 atgtgactct cgctgttgct gcagaagtaa acaaagaaga acaaaacctt ggtatcgtga
     2461 ttgatgctta tggagctggt ccatttatgg ttgcaactaa gatcaaagga atggttgctg
     2521 cagaagtttc tgatgaacgt tcagcttata tgactcgtgg ccacaacaac tcacgtatga
     2581 tcactatggg tgcacaactt gttggtgatg aattggctaa aaacatcgct aaaggatttg
     2641 ttaatggtaa atacgacggt ggtcgtcacc aaatccgggt tgacatgttg aacaaaatgg
     2701 gctaattaga ttatagtaag aaaggtaagt taaaaatgag aattgcaatt ggatgtgacc
     2761 acatcgtaac agatgaaaaa atggcggttt cagaattttt gaaatcaaaa ggatatgaag
     2821 tcattgactt tggtacatat gaccatacac gtactcacta cccaatcttt ggtaaaaaag
     2881 taggggaagc tgtaactagc ggtcaagctg atcttggagt atgtatctgt ggtactggtg
     2941 ttggtatcaa caacgctgta aataaagttc caggtgttcg ttctgccttg gttcgtgata
     3001 tgacaacagc cctttatgct aaagaacaat tgaacgctaa cgttattggt tttggtggta
     3061 aaattactgg tgaattgctt atgtgtgata tcatcgaagc tttcatccat gctgaataca
     3121 aaccaactga agaaaacaaa aaattgattg cgaaaattga acatgttgaa agtcacaatg
     3181 ctcaacaaac agacgcaaac ttcttcactg aattccttga aaaatgggat cgcggagaat
     3241 accacgacta agaggtaacc tatgatttta acagttacaa tgaacccatc cattgatatt
     3301 tcctatccct tggatgagtt gaagattgat actgtcaatc gtgtggtgga tgtaaccaaa
     3361 acggctggtg gtaagggact caatgttacc cgagtacttt cagaatttgg cgattctgtt
     3421 cttgctactg gtttagtggg tggcaaactt ggtgagtttt tggttgaaca tatcgataat
     3481 caagtaaaga aagatttctt ctcaattcag ggagaaactc gtaactgtat cgctattctc
     3541 cacggagaca accaaacaga agttcttgaa aaaggtcctg aagtattgga acaggaaggt
     3601 caagactttt tggaacattt caaaaaactc ttggagtcag ttgaagtagt ggccatctca
     3661 ggtagtctgc cagctggcct tccagttgat tactatgcga gcttggtaga acttgctaat
     3721 caagctggca agcctgtagt cttggactgc tcaggtgcag cacttcaggc tgttcttgaa
     3781 tcaccccata aaccaacagt catcaaacca aataatgaag aattgtctca gcttcttgga
     3841 agagaagttt ctgaggattt ggatgaatta aaagaagtac ttcaagaacc tttgtttgca
     3901 gggattgaat ggattatcgt ttcacttggt gccaacggta cttttgccaa acatggtgac
     3961 actttctaca aggtagatat tcctagaatt caggtggtaa atcctgttgg atctggagac
     4021 tctactgtgg caggaatttc ttcaggactt cttcacaaag aatcggatgc agaattactc
     4081 atcaaggcaa atgtccttgg tatgctcaat gctcaagaaa aaatgactgg tcatgtcaac
     4141 atggccaact atcaagttct atatgatcaa ttaatagtaa aagaggtata aaatggcttt
     4201 aacagaacaa aaacgtgtac gcttagaaaa actttctgat gaaaatggta tcatctcagc
     4261 tcttgcattt gaccaacgtg gtgctttgaa acgcctcatg gctcaacacc aaacagaaga
     4321 accaactgtg gcccaaatgg aagaacttaa agtcttggta gcagatgaat tgactaaata
     4381 cgcttcatct atgcttcttg accctgagta tggacttcca gcaactaaag ctcttgatga
     4441 aaaagctggt cttctccttg cttatgaaaa aacaggttat gacacaacaa gcacaaaacg
     4501 cttgccagac tgcttggatg tctggtctgc aaaacgtatt aaagaagaag gtgcagatgc
     4561 agttaaattc ttgctttact atgatgtaga tagctcagac gaactcaatc aagaaaaaca
     4621 agcctacatc gaacgcatcg gttctgagtg tgtggctgaa gatatcccat tcttccttga
     4681 aattcttgct tacgatgaaa aaattgcgga tgcaggttct gtagaatacg cgaaagtaaa
     4741 accacacaaa gttatcggcg ctatgaaagt cttttcagac ccacgcttta acattgatgt
     4801 cttgaaagtt gaagttcctg ttaacattaa atatgttgaa ggcttcgctg aaggtgaagt
     4861 agtttataca cgtgaagaag cagcagcctt cttcaaagcg caagatgaag caacgaactt
     4921 gccatacatc tacttgagtg ctggtgtatc agctaaactc ttccaagata ctcttgtatt
     4981 tgctcatgaa tcaggtgcaa actttaacgg agttctttgt ggccgtgcaa catgggctgg
     5041 atcagttgaa gcatacatca aagatggtga aacagcagct cgcgaatggc ttcgcacaac
     5101 tggatttgaa aacattgatg agctcaacaa agttcttcaa acaacagcaa cttcatggaa
     5161 agaacgtgtg taagaaagtc ctcctagttt aggaacatga atctaaaaaa atttaaaaaa
     5221 agttgtatgt aaaggtttac aaaataactt acttgtgcta tacttaaatc acaagttaat
     5281 acaaggtgag tgttactaag taatattagg catgatcaca ggtgaattag aaatcagctg
     5341 attttctagt tcatttgtgg tcattttttg tactcatata cctttaagat ataaaaggag
     5401 gttgacatgt atcgaattct aaatccaatg aatcacaatg tctcgcttgt cagaaatgat
     5461 aagggagaag aggtgattgt aattggtaag gggattgcat tcggaaagaa gaagggggat
     5521 ttgattgctg aaaatcatgt tgagaaaatc tttcggatga agaccgaaga gtccagagaa
     5581 aactttatgg ctcttctcaa agatgttccg cttgatttta tcacagtgac ctatgaaatc
     5641 attgataagc tatcaaagaa atatcattat ccgattcaag agtatctcta tgtaaccttg
     5701 acagatcata tttactgttc ttatcaagct ctaactcaag gaaggtacaa ggatagtaat
     5761 ctgccagata tttctgctaa gtatcctgtc gcttttcaaa tcgcaaatga agcttttgaa
     5821 atttactgtc agaagctagc agatcatttt cctgaggacg aaattattcg gattgcttat
     5881 catttcatta atgctgaagg tgaaaatgaa gtggaacttg tggagtcgat tgataagagg
     5941 aaagaaattc tcaggaatgt tgaagaagtt ttaacggact atgcaattca acgaactaaa
     6001 aagaataacc atttctatga tcgctttatg atccatttga attatttctt ggattattta
     6061 gacagatcta gagatgataa ccaatcactt ctggatatgg aagatcatat taaacaatcc
     6121 tatccaaaag ccttcgagat tggttccaag atctatgatg tgattacgca acatacgggt
     6181 cttgatttgt ataaaagtga acgagtttat ctagttctac atatccaacg tttattgtca
     6241 taaaaattta tttaaaacta tataaggaga attctatcat gaatagagaa gaagtaacat
     6301 tgttaggttt tgaaatcgta gcctatgctg gcgatgctcg ttcaaaacta ttggaagcct
     6361 tgaaggctgc tgaagctggt gattttgaaa aagcggacgc tctggtagag gaagctggta
     6421 gctgtattgc agaggctcac cacgcgcaaa caagtctatt gactaaggaa gcttctggtg
     6481 aggacttagc gtatagtgtg accatgatgc atggtcaaga tcacttgatg acaactatct
     6541 tgttaaaaga cctaatgcac catttaattg aactttacaa gagaggagtt aaataaaatg
     6601 gataagttaa taatttttat tgagaaagga aagcctttct ttgagaaatt atcgagaaat
     6661 atatacttaa gagcgataaa agatggtttt atttccagta tgccagcagt attattctca
     6721 agtattttta tactaatagc tgctgtgccc aatatttttg ggtttaaatg gtctgatgaa
     6781 cagttagctt ttattttgaa accttacaac tactcaatgg ggattttagc tctcttagta
     6841 gctgggacaa ctgcaaaatc gttaacagat tcagttaata cacgtagtat ggagaaaacc
     6901 aaccaaatca actacatgtc aactttttta gcagctgttg ttggattgtt aatactggca
     6961 gctgatccaa ttgaaggtgg atttgctaat ggtcttttag gtactagagg attacttact
     7021 gcatttttgg cagcttttat tacagtaaat atctataaag tatgtattaa aaataatgta
     7081 accattagac ttcctgaaga ggttccacca aatattgcac aagtttttaa agatgttatt
     7141 ccgtttgcct tatctgttct ttcaatatat ggattggatt taattgttag aaatattttt
     7201 ggtacaaatg tagcagaatc tgttggtaaa atattagccc ctctattttc agctactgat
     7261 ggttatatcg gtttagctat tgtatttggt gcttatgctt tcttttggtt tgttggaatt
     7321 catgggccat ctgttgtaga acctttaatt gtagctatca gttatgcaaa tatagaagct
     7381 aatgttcagc ttgtgcaagc tggtatgcac gcagataaaa ttttaaatcc agttactcaa
     7441 acttttgttg taacaatggg tggtactggt gcaacactag tagttccatt tatgtttatg
     7501 tggttatgta aatcaaaaag aaatagaatt gtcggacgtg cgtctgtagt tcctactttc
     7561 tttggcgtaa atgaaccaat cctatttggt gctccaattg ttttaaatcc tatcttcttt
     7621 attccgtttg ttactgctcc tattatcaat gtttggatta tgaaattttt tgtagatgtt
     7681 ctacaaatga atagtttcag tattatttta ccttggacaa cacctgctcc aattggtatt
     7741 gttatgggaa cggcgctggc tccattgtca ttcgtcttgg ctataacttt aatcattatc
     7801 gacactttaa tctattatcc atttgttaaa gtttatgacc atcaaatttt agaagaagaa
     7861 cggaaaggaa actcttcatc tgaattgaaa gaaaaagttg ctgcaaactt caacactgca
     7921 aaagcggatg ctattcttga aaaagcgggt gtagaagcag cacaaaatac aatcactaaa
     7981 gaaacaaatg tcctcgttct ctgtgcaggt ggaggaacaa gtggtctcct tgcaaatgct
     8041 ttgaataagg cagcagcaga atacaatgtc cctgtgaaag cagcagcagg cggctatggt
     8101 gctcaccgtg aaatgttacc agagtttgat cttgttatcc ttgcccctca agttgcttca
     8161 aactttgaag atatgaaagc agaaacagat aagctcggta ttaaactagc gaaaacagaa
     8221 ggcgctcaat acatcaaatt aactcgtgat ggaaaaggtg ctcttgcatt cgtacaagcg
     8281 caattcgatt aaggctagag actctgaaat agtctcctat cgttacggaa atcgctatgg
     8341 cgaatttcct attattaatt cgtcggtaaa aagatatcgt ttttacctcc tcatgtcaca
     8401 attcggtgac ttggtacaag aagtgagatg gagaaggatg gctcattgac tcctctcctc
     8461 tcacttttac tttatttaaa tcaagaaata ggtgaaaaaa atgacaaaaa cacttccaaa
     8521 agactttatt tttggtggcg caacagctgc ctatcaagca gaaggtgcta cacatactga
     8581 tggtaaagga ccagtagcgt gggataaata tcttgaagat aactactggt acactgcaga
     8641 accagccagt gatttttaca atcgatatcc agttgacctc aagctagcag aagagtatgg
     8701 tgtcaatggt attcgaattt ctattgcttg gtcacgtatt ttcccgactg attacggcca
     8761 agtaaatgct aaaggtgttg agttttatca taatttattt gcagagtgtc acaaacgtca
     8821 tgttgagcct tttgtaactc ttcatcactt tgacacgcca gaagctctcc actcaaatgg
     8881 agacttctta aaccgtgaaa atatcgaaca ttttgtagac tacgctgcct tctgttttga
     8941 agaatttcca gaagtaaact attggacaac ctttaatgaa attggaccaa tcggtgatgg
     9001 tcaatatttg gttgggaaat tccctccagg tatccagtac gaccttgcca aagtctttca
     9061 atcacaccac aatatgatgg tgtctcatgc acgcgcggta aaattgtaca aagagaaagg
     9121 ctataaaggg gaaattggtg ttgttcacgc cctgccaact aaatatcctc tagatcctga
     9181 aaatccagca gatgttcgtg cagctgagtt ggaagatatc atccacaata aattcatctt
     9241 agacgcaact tatctaggtc gctattcagc tgaaaccatg gaaggtgtca accatatctt
     9301 atcagtcaat ggtggtagct tggatcttcg tgaagaagat tttacagcat tagaagctgc
     9361 aaaagacttg aatgatttcc taggaatcaa ctactatatg agtgactgga tggaagcctt
     9421 tgatggagaa actgaaatta tccataatgg taaaggtgaa aaaggaagct ctaagtatca
     9481 aatcaaaggt gttggtcgtc gtgtagctcc tgactatgta ccacgcacgg attgggattg
     9541 gattatctac cctcaaggtt tgtatgacca aatcatgcgt gtgaagaaag attatcctaa
     9601 ctacaagaag atttacatca ctgaaaatgg tctcggctat aaagatgagt tcgttgataa
     9661 cactgtttac gatgatggtc gtattgatta cgtgaaacaa cacttggaga tcttgtctga
     9721 tgcgattgca gatggagcta atgtaaaagg ttacttcatt tggtcattaa tggatgtctt
     9781 ctcatggtca aacggttatg agaaacgtta tggtctcttc tacgtagatt ttgaaactca
     9841 agaacgttat cctaagaaat cagctcactg gtacaagaaa gtagcggaaa ctcagattat
     9901 agactagtag aattagtcat tagatataga attttagtga gtcaaaaaga tgttcaaaga
     9961 ttttatccaa tctatttatg aaaaaaagtt tatattataa atttcgaaaa atgctctcaa
    10021 ataccgtgtt tgacgagtga agaattgaaa agtcttggaa aatggtatgt ctcgactggt
    10081 aaagaatgga tttgtcattc agatgatgag ctggaagaat ttaaaaatct atttttaaat
    10141 tttatcaatc ctgaagaatg ggatactatc tcctttgatt cagattttat gccgtttcaa
    10201 caatcgtaac caatttctca aaaaagttaa atcttatatt tagtactctg taaaactctt
    10261 atctaatcac gttgcttata ctcaatgaaa atcaaagagc aactttaaac taggaagcga
    10321 gtcgcagatt tctcaatgca tagctttgag gaattgggca aaaagtcttt gatatagaaa
    10381 aaagcatagt atcaggtgtt gaaacacctg atactatgct ttttattgtg ggaagattta
    10441 ctttttttct tctgaaattg agttgttacc caggctcttt cagtttatta aggcttgatg
    10501 actttaatgt gtttagatag cttaaaaagg attgaatcac ttagtttaga atctgaaaca
    10561 atagtatcaa gatttgatat attataaaaa gtataaaaat caaacttatt gaacttacta
    10621 tgatctgcga gtaaatattt tttattagaa ttatttaaag cgatgcgttg agcctctccc
    10681 tcttcctcgc taaaagtagc tagagctccg ttttgaatac cattacagct aacgaaagct
    10741 ttagaaaatt ggagattaga gagattttgt agggtcaatg tgccaacaaa agcacctgta
    10801 atatcgcgat aatttccacc tatcaaaatc aaatctgtta attttcgttc gcttaaaatc
    10861 agaaaaacag gtagactgtt ggttacgacg cggatattgt caataggcaa ctcacgcgca
    10921 aaaaactcta atgttgttcc tggtccaatg aaaatagttt ctctttcttc tactagactg
    10981 cctgcaaaat gggctatttc ttgtttttct gccgtttgga gggcttgttt ttcaatattt
    11041 gatcgctcat tagtcaaaag ggagttggtt cgaagttttt cagctccacc atgcacacga
    11101 atcagcaaat ctttatcagc taattcctgt aaatagcgcc ttgcagtcat atctgaaacg
    11161 gctatttcgt ccataatctg tttaactgtt atggttcctt tactatttac tatctctaaa
    11221 attttggtta atttttcttg tttgagcata ttatcacctc gtttcctact actatcttac
    11281 cataaacaaa ctcatcattc aaatacaaaa acaacaaaat gaaacaaaaa caaaaatatc
    11341 gaagtttgtt ttcaaaactt tcgatatttt tgttgggtta ttattttgtt gtttctagtt
    11401 tactttttga tggttaagag tggtggagaa ttatactcaa tgaaaatcaa agagcaaact
    11461 aggaagctag ccgcaggctg tacttgagta cggcaaggcg aagctgacgt ggtttgaatt
    11521 tgattttcga agagtattag tccaaaccgt agttgtagtc atcatcttgc atggcttcaa
    11581 cttcgccaag aaggtaacca tttccgactt gagagaagaa gtcatggttg gaagttcctg
    11641 ttgaaatacc gttcataacg attgggttga catcttcagc tgaatctggg aaaagtggat
    11701 cttgtcccat gttcatgaga gctttattgg cattgtagcg aaggaaggtt ttaacctctt
    11761 cagtccaacc aacaccgtca taaagactct ctgtgtagcc ttcttcattt tcataaagag
    11821 tatagagtag gtcgtacatc cattctttga gtttttcttg ctcttcttca ggtaattcat
    11881 tgaaaccaag ttggaatttg taaccaatgt aggttccgtg aacagactcg tcacgaataa
    11941 tcaatttaat gatttctgca acgttggcaa gtttgttgtt accgagatag tagaggggag
    12001 tgaagaaacc agagtagaag aggaaggttt cgaggaagac gctggcaact ttcttttcaa
    12061 gtgggctgcc gtttaggtag atttcgttga caatctcagc cttcttttgt aggtaaggat
    12121 tggtattggt ccattcgaaa atttcttcaa tctcagcctt agtattcaag gtagaaaaga
    12181 ttgatgagta agatttagcg tggacagatt ccataaattg gatgttattg aaaacagctt
    12241 cctcatgtgg tgtacggatg tctgcgcgaa gggcttgaac cccagtttca gattgcatag
    12301 tgtcaagaag ggttaaacca ccaaaaactt ttccgaccaa gtctttctct ttgttagata
    12361 gctttctcca gtcatccaag tcgtttgata agggaatacg tgtatcgagc caaaattgct
    12421 ccgtcagttt ttcccaagtt gatttgtcga tgacatcttc gatggcattc cagttaatgg
    12481 ctttgtagta agtttccatt taaaatctct ttctgtgttt agtattgcga actcacaatt
    12541 atttctactt taccataatt ctataggagt atcgcacaaa aagtcggaag cccgactttt
    12601 aaaatgttac ataaattatg ttatgacata gtagatttga ttttatcagt gctgcttagg
    12661 gaaaaatagt gtttctatgc tagaaactaa atcacacagc tttcacattg gttggcgccg
    12721 acttctccac cgtcatctgt aaaggtacgg acgtagtaga tagacttgat tcccttgtta
    12781 aaggcatagt tacgaaggat ggacaagtca cgtgtcgttt gtttattttc cctcttccat
    12841 tcgtaaaggc cttttggaat gtcactacgc atgaagaggg tgagtgaaag tccttgatcc
    12901 acgtgttcag tcgcagcagc gtaaacatcg atgactttac gcatatccat atcgtaggca
    12961 gaagtgtagt aaggaatggt ttctgtagac aagccagcag cagggtagta gattttacca
    13021 attttctttt cctgacgttc ttcaatacgt tgcgtaatcg ggtggataga agcagaaaca
    13081 tcgttgatgt agctgataga accatttggc gctacagcaa ggcgattttg gtggtaaaga
    13141 ccatcctctt gaaccttgtc gcgaagttca gtccaatcag caacaccagg gataaaaaca
    13201 tttttgaaga gttctttaac acggtctgat gttggaacaa attcaccagt tacatacttg
    13261 tcaaagtaac ttccgttagc atagtctgat ttttcaaagt tgtggaaggt aataccacgt
    13321 tcacgcgcaa tattgtttga ctctaccaag gtccagtagt tcataagcat aaagtagatg
    13381 cttgtaaatt caacagactc aggtgaacca tattcaatga gttgttgggc aaggtagctg
    13441 tgcagtccca tggcaccgag accaaaggtg tgggcttggc tatttccatg gtcaatcgtt
    13501 ggtacagcta cgatatgtga actatctgta acgaaagtaa gggcacgaac catagcacgg
    13561 atagaacgac caaaatcagg tgaagtcatc atgttaacca cgttggttga acccaggtta
    13621 catgaaacat ctgttcccat ttgaaggaat tcttgagcat cgttgatcaa gcttggttct
    13681 tgaacttgaa gaatctcaga acacaagtta ctcatgataa tctttccatc gacaggattt
    13741 gcacggttag ccgtatctat gttgactaca taaggatagc cagactcttg ttgcaattta
    13801 gagatttcag tttccaaatc ccgcgccttg atttttgtct tgcgaatatt tggatttgcg
    13861 accaattcat cgtatttttc agtaatgtcg atgtaattga atggcacacc gtattctttt
    13921 tctacagagt aagggctgaa gaggtacatt tcttcatttt tacgagccaa ttcgtagaat
    13981 ttatcaggta ctacaacacc aagtgataga gtcttgacac gtactttttc atcagcgttt
    14041 tctttcttag ttgaaaggaa agcgatgata tctgggtgaa agacgttgag gtagacaaca
    14101 ccggcacctt gacgttgccc caattggttg gagtaagaga agctgtcttc aaaaagcttc
    14161 ataacaggaa cgacacctga agcagctcct tcatagcctt tgataggtgc accagcttca
    14221 cgaaggttgc tgagggtaat tcccacacca ccaccaatac gtgaaagttg aagagctgag
    14281 ttgatagaac gtccgataga gttcatatca tccgtcactt ggattaggaa acaagatacc
    14341 aactccccac gacgagcacg tccagcattc aagaaggaag gagtagcagg ttggtagcgt
    14401 tggtggatga tttcattggc aatatcgatt gcaacagctt cattcccatc agcgaaataa
    14461 agggcgttga agaagacacg gtcttccata ttttcaagat agtattcacc gtcattagtc
    14521 tttaaggcat attgattgta aaatttataa gctgccatga atgacttgaa ttggaagttt
    14581 tggtctttga taaattgagc caattcttcc aagaactctg gacggtattt cttgataaag
    14641 gctgtttcga tgtagttgtg ttcaatgagg taattgattt tgtctttgat tgaatcaaaa
    14701 accatagtgt ttggaactac attttcttta aagaaagcat ccaaggcttc cttatcttta
    14761 tgaagcatga tttgtccatt aacaggacgg ttaatttcgt tattaagacg gaagtaagtc
    14821 acgtcttcaa gatgttttaa tcccataaaa tttcccttat ctaattacaa aagaaaggct
    14881 tctaagttag ccctaaaagc agtttcttct ggatgatgta ctaagattat gctaattgtt
    14941 tcagtttttc tggttggaaa cctgaaaaga cttcagttgg tgtttggata acaggagctg
    15001 cgctaaaacc gagctcttta acttgatcga cgtactcagg ttgctcatca agattgattt
    15061 cacgataaga gacattatta ctgtccaaga aacgcttggt cattttacat tggacacaat
    15121 tgtttttaga ataaacggtt accattgtgt aactcctctt caaaatttaa tactatctta
    15181 gtatatcaga aaataaaatt ttgtcaatga tttaaactaa atatagtggt gttctttt
//
LOCUS       DAVKUR010000045        15052 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKUR010000045 DAVKUR010000000
VERSION     DAVKUR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.045"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     regulatory      79..167
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            382..1050
                     /locus_tag="VW749_001614"
     CDS             382..1050
                     /locus_tag="VW749_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0175627.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     gene            complement(1200..1286)
                     /locus_tag="VW749_001615"
                     /pseudo
     CDS             complement(1200..1286)
                     /locus_tag="VW749_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            1377..2159
                     /gene="thiM"
                     /locus_tag="VW749_001616"
     CDS             1377..2159
                     /gene="thiM"
                     /locus_tag="VW749_001616"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0175628.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            2161..2790
                     /locus_tag="VW749_001617"
     CDS             2161..2790
                     /locus_tag="VW749_001617"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0175629.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGAITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      2999..3087
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3349..3909
                     /locus_tag="VW749_001618"
     CDS             3349..3909
                     /locus_tag="VW749_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0175630.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            3910..5295
                     /locus_tag="VW749_001619"
     CDS             3910..5295
                     /locus_tag="VW749_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175631.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            5297..5947
                     /locus_tag="VW749_001620"
     CDS             5297..5947
                     /locus_tag="VW749_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0175632.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            5958..6650
                     /gene="tenA"
                     /locus_tag="VW749_001621"
     CDS             5958..6650
                     /gene="tenA"
                     /locus_tag="VW749_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0175633.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            6655..7179
                     /gene="thiW"
                     /locus_tag="VW749_001622"
     CDS             6655..7179
                     /gene="thiW"
                     /locus_tag="VW749_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0175634.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            7179..7982
                     /locus_tag="VW749_001623"
     CDS             7179..7982
                     /locus_tag="VW749_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0175635.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLNYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            7975..8607
                     /locus_tag="VW749_001624"
     CDS             7975..8607
                     /locus_tag="VW749_001624"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0175636.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8816..9607)
                     /gene="thiD"
                     /locus_tag="VW749_001625"
     CDS             complement(8816..9607)
                     /gene="thiD"
                     /locus_tag="VW749_001625"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0175637.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQAKDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(9691..9789)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9973..10368
                     /locus_tag="VW749_001626"
     CDS             9973..10368
                     /locus_tag="VW749_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0175638.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            10379..10750
                     /locus_tag="VW749_001627"
     CDS             10379..10750
                     /locus_tag="VW749_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0175639.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            10760..13003
                     /locus_tag="VW749_001628"
     CDS             10760..13003
                     /locus_tag="VW749_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0175640.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            13210..14985
                     /gene="spxB"
                     /locus_tag="VW749_001629"
     CDS             13210..14985
                     /gene="spxB"
                     /locus_tag="VW749_001629"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0175641.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
BASE COUNT         4427 a         2767 c         3327 g         4531 t
ORIGIN      
        1 tatatataaa gatatttttc ggtcaaatat cttgctaggg ctttcatttt ttgctatact
       61 ggttcagtaa ttaaataata gagacatttg gggtgcttta ggctgagata atacccattg
      121 aacctgatac agttaagact ggcgaaggga aatgtgaaca gttttttcgt atggtgaaat
      181 gaacggtcta atcttgtaag tcaactctaa ttcttgattg taattggagt tttttgttta
      241 tataaactgg ataggcttgt ttagttagct ctctgcaaat gctctcgatg tgctttaaaa
      301 ggatcaagtg gaattacgat tttgcttgat atttcttggt gttttattaa ttactaacaa
      361 gtaaagagag gagaagtaaa tatggaaaca caagactatg catttcagcc aggtttgact
      421 gttggagaat tattaaaaag cagtcagaag gattggcagg ctgcaatcaa tcatcgtttt
      481 gttaaggaac tttttgcggg gacaattgag aataaggtct taaaggacta tctgattcaa
      541 gattatcact tctttgatgc cttcttatcc atgctgggtg cctgcgtagc tcacgcagat
      601 aaacttgaat ccaagcttcg ttttgccaag caactaggct ttcttgaagc agatgaagat
      661 ggttatttcc aaaaggcttt taaagagtta aaagtagcag agaatgacta tctagaagtg
      721 actttgcacc ctgtaacaaa agcctttcag gatctaatgt attcggcagt ggcttcatca
      781 gactatgccc atcttttggt tatgctggtc attgcagaag gtctctattt agactggggt
      841 tctaaagatt tggctctacc tgaagtctat attcattcgg aatggatcaa tctccacaga
      901 ggtcctttct ttgcagagtg ggttcaattt ctggttgacg aactcaatcg tgtcggtaaa
      961 aatcgagaag atttgacaga acttcagcaa cgctggaatc aagcagtcgc tttagaatta
     1021 gctttttttg atattggtta caatgtctag agaaggctca tgatatttac aaatttgatg
     1081 aggtaagact cttcgaaaat ctcttcaaac aacgtcagtt tcaccttgcc gtaggtatgg
     1141 ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcgtca
     1201 gtcttatcta caggttcaaa gcagtgtttt gagcaacctg cggttagctt cctagtttgc
     1261 tctttgattt tcattgagta taaatcattc aatgtaaatg aaaaaaattt cttaacgaaa
     1321 gatagatata aatcgaaatc agtagatcgt ataaagtgaa aaggaaggat ttcaatatga
     1381 caagtttaaa attattaaaa gaaaaagcac cattggtcat ttgtataacc aatgatgtag
     1441 taaaaaattt cacagcaaat ggattagtag cactgggcgc ctcaccagcc atgagtgagt
     1501 ttccagcaga tttagaggat ttgttaaagt atgctggtgg tttattaata aacataggaa
     1561 cattgacaga tgaaaattgg aaattatacc aagctgctct gaaaattgcg gagaaatata
     1621 atgtcccagc agttttagat cctgtagcct gtggagcagg agaatataga aaaaaagtag
     1681 cggatgatct aatcaacaat tataaactag cagcgattag aggaaatgct ggcgagattg
     1741 cctctttagt aggaatagat gtggcatcta aaggagtaga tagtgcgggc gtagataata
     1801 ttgacgaaat tgctctagca gcaaatgaga agttcaatat tccaatagta gtaacaggtg
     1861 aagtggatgc cattgctgtt aatggagaag tggtaacgat tcataatggt agtgctatga
     1921 tgccgaaagt cattgggaca ggatgcttat taggagctgt agtagcaagc tttatcggac
     1981 tagaaaaagg tcaagaattg aaatcattag aaacagcaat gttggtttac aatatcgctg
     2041 gagaaatagc agaaaaacgt cccaatggac atcttcctgg aacatttaaa gctgaattta
     2101 taaatgcctt atacgagatt acagatgaag atgtaaagga attcaaaaga gtgaagtaag
     2161 atgtttcata aagaattact aaaactatat tttatttgtg gaacgactac ttgccaagga
     2221 aaaaatctat atacagtcgt tgaggaagcc ttaaaaggtg ctataacctt atttcaattt
     2281 cgagaaaaag gtgagggtgc tttagaaggc ttagaaaaac ttgagctagc tatccaaatt
     2341 aaagaacttt gtaaaaaata caatgttcca tttatcgtta atgacgatat agatttagca
     2401 atggaaattg acgccgatgg cgtacatgta ggtcaagatg atattggtgt tgatgaaatt
     2461 agaaaattga tgccagataa aataattggt ctttctataa gaaacgaaga agaatttcaa
     2521 caatcaaaag ttgaatatgt agattatgta ggtgttgggc ctgtatttga tacccagtca
     2581 aaagatgatg ctggtggtgc tataggttat gaaggtcttg aattgatgag aaaactattg
     2641 ccacaaatgc ctttagttgc aattggtggg atacagacga aacatattaa agacattata
     2701 aagaccaatg ttgacggcgt ttcaatcatt tcggcaatat cgtatgcaaa aaatatagaa
     2761 aaaactgttc gggaaatgag tgaacaatag atatctatcc ttggattcta agtaagtagg
     2821 attttccttt tttaaaaagc tatgtctaga ttcagcttga atggctaatt catcaaacag
     2881 gtcatttgtt ttttgcaaaa gaaagatctg ctgtctttgt gagtgcaagg ctgtatttcc
     2941 agttcaattt cttgaactag tataaaatgt gtgttataat aatcacataa ttaaataata
     3001 aaggcatttg gggtgcttta ggctgagatg atacccattg aacctgatac agttaagact
     3061 ggcgaaggga aatgtgaaat gtttttttcg tatgtcgaaa agaactgtct aatcttgtaa
     3121 gctgaactct aattcgtatc tgtaattaga gttttttctt ttacgaaact ggatgaagat
     3181 gatatagtag attgaaataa gatgcgaaca aatcaattag aaaattcaaa ttaatttcta
     3241 gaaatatttt agcattcctg tgtactgttc taaattcaat ctgctataca aagtatttag
     3301 gtcggtcttc ttgagtgccc cacttttctt ttaaaaaagg agttttttat gttgaaaaaa
     3361 tggcagttaa aagatgttat cttgcttgct ttcttgtcta tcttttttgg tggggttttc
     3421 gttggttcag gatatgtgta taatattctc agtctactct taacacctct tggtttgcag
     3481 gcctttgcca atgaaatcct cttcggtctc tggtgtatgg ctgcgcccat tgctgccatc
     3541 tttgttccga gagtcggaag tgcaacgatt ggagaagtgc tagctgcgct tgctgaagtc
     3601 ctttatggta gccaatttgg tctaggagct cttttgtctg gcttggttca aggtttggga
     3661 agtgaatttg gttttatcgt aactaagaat cgctatgaaa gttggctctc tctaactgct
     3721 aatagtattg ggattacgct tgttagcttt gtctatgaat acattaagtt aggttactac
     3781 gccttttccc ttccgtttgt cctttcctta cttgtggtac gttttatttc tgtttatttc
     3841 ttctgtacca tcttggttcg tgccattgtc aaactctatc atcagtttgc aactggagga
     3901 aaagcataga tgggtctgga actacgagcg attcagtccc caatcttctc tgagccgttt
     3961 gattttactt ttcatgcgca agcctttacc ttgttagttg ggagcagtgg ttcaggaaaa
     4021 tccagccttt ttcaagtcat tgcccaagtc agttctcttc cctatagtgg tcaagtcctg
     4081 atagatggga gcgaggtcag tcagctttct atcatcgcac gtgtccagaa ggttggcatt
     4141 ctctttcaaa atcccaatca tcaatttacc atggagaact tgtttgagga gctgattttc
     4201 accttggaga atatcggcta tcaccttcag gaaattgatt ctaaaatagc agaggttgtc
     4261 cagcaatgtc gttgcgaggc aatcttacac cgtcccattc atcacctatc aggtggggaa
     4321 aagcaaaaag cagcgctggc tgtcctcttt gccatgaatc ctagggtcta tctcttggat
     4381 gagcccttcg cttctattga ccgcaagagc agaatcgaga tattggagat tctaaaagag
     4441 ttggctcttg atgggaagac agttattttg tgcgaccatg atttatctga ctataaagcc
     4501 tatatcgacc atatggttga gctaagagac ggaaaactaa gggaagtgtt tcaaatccct
     4561 tcctatgaga tgacacaggt tgcttcaaag gaagttgctt ctagcccgga actattccat
     4621 atgaaccgtg tgactggtga gcttggtaat cgccccctct tttcaattgc tgatttcaca
     4681 ttctatcaag ggatttcctg tatcctgggt gacaatggtg tcgggaaatc aaccctcttt
     4741 cgctctattc ttcaatttca aaagtataag gggcgcattg catggaaggg gacagtcctg
     4801 aaaaagaaaa agagtttgta tcgtgatctg actggtgttg ttcaggaagc tgagaagcag
     4861 tttatccgag tcagtctgcg agaggagctt caattagatg gacctgattc tgaaagaaat
     4921 cagcggattt ttcaagcttt acgatatttt gatttggagc aggcagtcga taagagtccc
     4981 tatcaattaa gtggtggtca gcaaaaaatt cttcagctct tgaccatctt gaccagtaag
     5041 gcttccgtga tcttgctaga tgaacctttt gcaggtttgg atgatagagc ctgccattat
     5101 ttttgcaagt ggattgtgga ggagaggaat caaggaagaa gttttctgct cattagtcat
     5161 cgtttagacc ctttgatttc tgtggttgat tattggattg agatgactag tcagggtctt
     5221 cggcatgtga aagaagtgac cattaccaaa ccacttacat ctcagagtag caatacccaa
     5281 ggggaggtga gatagtatgg tcaaagtagc aacccagaca ccgattatca gtctcttctt
     5341 gctgatttta tccttggaaa catctttcat tccttcgatt gctctgaatc tttcggtagt
     5401 cgcattttgt attctcttta tgctctatta ccgtcgattt aaaatgttag cttggatgat
     5461 catacttgcc attttaccat cttttgccaa ctactgggca gttcagttac acggagatgc
     5521 ttcacaggca gtcatgcttg gaacgagggc ctttgtgaca gtttgtatcg gccttgtctt
     5581 tgtttcctct atttcactaa aagagcttct cttgtacttg gctcaaaagg ggctatcacg
     5641 ctcttggtcc tatgccttga ttgtggtatt caattccttt cctctcattc agcaagaaat
     5701 caagtccctc aaagaagctt gcctattacg tggtcaagaa ctgcattttt ggtcgccctt
     5761 gatttacagt aaggttctga tgacagtctt taggtggcgc catctttacc tgagagctct
     5821 gtctgctcat ggatatgacg aacatgcaca gttgaagaat agctatcgga ctttttatat
     5881 tcctaaaaaa acaaaattaa tctacctgct tttcttttta ttgcttcaaa ccagtctatt
     5941 tttataaagg agttattatg gaatttacag atattgcgat ggaattatcc aagaaagctt
     6001 ggcaggcttc ctttcatcat ccctttattt tacaattaca agaggggaat ttagaacctg
     6061 ccattttccg ctattacctg attcaggatg cctactatct gaaggccttc tcagaaatct
     6121 atcatctttt ggctgataag acttcaaacc aagagatgaa aagactcttg aaacaaaatg
     6181 ctcagggttt agtggagggt gagttattta ttcgccaaca atttttcaag gaaatggaaa
     6241 tcagcgacca ggaaatggag caacatccaa ttgctccaac ctgttatcat tacatttctc
     6301 atatttatag gcaatttgca gaaccgaact tagccatagc ttttgcaagc ttgcttcctt
     6361 gtccttggtt ataccatgat ataggcaaat cacttaatct taaaccatca ccaaatcctc
     6421 tctatcaaca atggattgaa acttatatta cggatgagtt agagcaacag atcagagagg
     6481 agggagcact ggtcaatcag ctctatcgag aaagtgatga gacagataag caaaaaatgc
     6541 tagatgcctt ccacatcagt gttcatatgg aagccaagtt ttgggagatg gcttaccaac
     6601 accagacatg gaagagcgat ttacagtctt tagaaaaagg agaagaatag aaacatgaga
     6661 aagcaccaac tacaagttca caaattgacc attttatcta tgatgattgc ccttgatgta
     6721 gtccttacac ctatctttcg aattgaggga atggcaccga tgtccagtgt agtcaatatt
     6781 ctagcgggaa tcatgatggg acctgtttat gccttggcca tggctacagt cacagccttt
     6841 atccgtatga cgactcaagg gattccgcct ttagctctca caggagcgac ttttggagcc
     6901 cttctggcag gtctctttta taagtacggt cgaaaatttt atttttctgc cttgggagaa
     6961 attgtgggaa caggtattat tggttccatt gtttcctatc ctgttatggt actctttaca
     7021 ggatcagctg ctaagcttag ctggtttatc tacacgcctc gatttttcgg agcaaccttg
     7081 attggtacag cgatttcctt tattgccttt cgatttttaa tcaagcagga attctttaaa
     7141 aaagtgcagg gatatttctt tagtgaaagg atagactgat gcaggaattt acaaatccct
     7201 ttcctatagg ctctagttcc ctaattcact gtatgaccaa tgagatttct tgtgagatgc
     7261 tggcaaatgg gattttggct ctgggatgca aacctgtcat ggcagatgat ccccgtgagg
     7321 ttcttgattt tactaagcaa agtcaggctc ttttcatcaa tttggggcat ttgtcagctg
     7381 agaaggaaaa agcaatccgc atggcagctt cgtatgcaaa ccaatcttct ctcccgatgg
     7441 tagtagatgc ggttggcgta acgacttcat ccattcgtaa gagcttagtt aaagaccttt
     7501 taaactatag acctacggtc attaaaggaa acatgtcaga aattcgaagt cttgttggct
     7561 taaagcacca cggcgttggg gtcgatgcga gtgctaaaga tcaagaaacg gaggatttgc
     7621 ttcaagtctt gaaagactgg tgtcagacct atcctggtat gtcattctta gttactggcc
     7681 ccaaggacct catcgtttcg aaaaatcagg tcgctgtact ggagaatggc tgtactgaat
     7741 tagactggat aacagggaca ggagatttgg ttggagcctt aacagccgtt tttctcagcc
     7801 aaggaaagac tggttttgaa gcttcttgct tagcagtctc ttatctcaat atcgctgctg
     7861 agaaaatagt tgttcaagga atgggattgg aagaatttcg ttaccaagta ctcaatcagc
     7921 tttcgctcct aagaagagat gaaaattggc tagataccat caaaggagag gcttatgaat
     7981 agagaagcac ttagactata tctggtaacc aatcgctatc aagattccgt ggaaagcttt
     8041 cttgcaaaag ttgagacggc ctgccgttca ggggttacca tagtccaatt gcgagaaaaa
     8101 aatctcacaa ccaatcaata ttatcaactg gcaaaacaag tcaaggaaat aacagatgcc
     8161 tatcaggtac ccttgataat cgatgatcgg ttggatgttt gtcttgcggt tgatgctgct
     8221 ggtctgcata ttggagatga cgaactccca gtttcggttg cccgacaagt cttgggtcct
     8281 gaaaaaatcc tcggtgtcac cgctaaaacg gttaaaagag ctctggaagc ggagaaatca
     8341 ggtgcagatt acttggggac aggagccatt tttccgacaa ccaccaagga aaatgcaccc
     8401 atcaccctga tttcaacctt gaaaacaatt tgccaaacgg ttgccattcc aatagttgct
     8461 attggcggct tgacttcgga gaatattgat cagcttatgg gcactggcat agctggtgta
     8521 gctgttgtac gtgatttgat gcaagcagaa gatattgagg caaaaacgca agccttttta
     8581 acaaagttgc atgacattct ttcctaatta atactcaatg aaaatcaaag agtaaactag
     8641 aaagctagtc gcaggttgct caaagtactg ccttgaggtt ttagataaga ctgacgaagt
     8701 cagctcaaaa cagtgttttg aggttgcaga tggaagctga cgtagtttga agagattttc
     8761 gaagggtata aaaactctct aattccctta aagtgggaac tagagagttt ttttcttaat
     8821 ctttaaaagt tgtatggttg actggaccag aaccatgacc gagttgaggg gcatcttgaa
     8881 tagcttttgt gataaaggcc ttggccttat caactgcctg gtaaagactc ttgcccttgg
     8941 ctagttcagc agtaatcact gcagcaaagg tacatccagt accatgggtg tgacaggttt
     9001 gaattcgtgg gctttcccag acaaattgtt cattcttggt aaagaggaaa tctttagcac
     9061 cacctttgag atgtccgcct ttgataacca cagactgagg accaaattct tttaaaatca
     9121 ggcgaccagc acgctgcatg tcttcggggt catggattga aaaaccaaca atctcttctg
     9181 cttcaggaag atttggcgta ataatagttg ctagaggtag taagtttgtt ttgagatagt
     9241 ctctagcatt tgagtcaatc aaggcatctc cacttgtagc aaccataaca ggatcaagga
     9301 catagggaca atccagtttt ttaagatagg gttggatgat ttccatgatt tcagtagtag
     9361 ccaacattcc agtttttaca gcctgaggtg gaatatcaga aaagacactc tccaattggg
     9421 ctttcaacat ttgaggagaa acgtgctcga ttagctgaac acctctggta ttttgagcga
     9481 caagactggt tacaacagcc attccataga catctttcgc ttggaatgac tttaaatctg
     9541 ccataatgcc agcaccacca ctagggtcag tccctgcaat ggtcaaagca acgggtaaat
     9601 aagtcatcta aaacctccca accaactgaa gtttgtattc ttaagaacaa gctagtctgt
     9661 tttagaaagg caatagaaga ctgctagtcc ccattatcat ttccacttcc atcagctagc
     9721 attacctaga ttgagtcaga gggatctaac agtcgttaat ctcagcttta cgcaccccta
     9781 gtggttgttt tcttttttct ttagtatagc atatttttat tgtttatata gtaatatttg
     9841 actgcaaatc gtttttcaaa tgattaaaat tctatttttc gaagaaaata ttatttctat
     9901 aattgacaaa tgtagatttt aagagtatac tgatgagtgt aattgacaaa tgtagatttt
     9961 ggaggtatgg taatgcagat ttcagatgca gaatggcagg tcatgaagat tatttggatg
    10021 cagggggagc agaccagtac agatttgatt agggttttgg cagagcggtt tgactggtcc
    10081 aagtccacgg ttcagacact tttggctcgt ctggttgaga aagagtgttt gactcggaaa
    10141 aaagaaggca agtcctttgt ttattcagcc cttttaactc tagaccaaag tcgggattta
    10201 cttgtccaag atatcaaaga caaggtttgt tcccgtagga ttaggaattt gttggctgac
    10261 ttgattgtag aatgtgaatt tactcagact gacttggaag acttggaagc tgtgatttca
    10321 gagaagaaat caagtgctgt aacagaagta agatgtaatt gtatgtaaag gagacgtcat
    10381 gttaaatagt attgtaacca ttatttgtat tgcccttatc gcgtttatct tgttttggtt
    10441 tttcaaaaag cctgaaaaat ctggacaaaa agcccagcaa aaaaacggat accaagagat
    10501 tcgagtggaa gtcatgggag gctatactcc tgagttgatt gtcctcaaga aatcagtgcc
    10561 agcccgcatt gtctttgacc gcaaggatcc ttcaccatgt ctggatcaaa ttgtttttcc
    10621 agattttggt gtacatacga acctgccaat gggggaagag tatgtagtgg aaatcacgcc
    10681 tgaacaggct ggagaatttg gctttgcttg tggtatgaac atgatgcacg gcaagatgat
    10741 tgtagagtag gtggagacta tgacagaaat tgtgaaagca agcttagaaa atggcattca
    10801 aaaaatccgt atccgatctg aaaaaggcta tcatccagcc catatccagc ttcaaaaggg
    10861 aattccagct gagattacct ttcatcgtgc tactccttca aactgttata aggaaattct
    10921 gtttgaagaa gaaggtatct tggaaccaat cggcgtagat gaggagaaag tcattcgttt
    10981 tacacctcaa gaattagggc gacatgaatt ttcttgtggc atgaagatgc aaaagggaag
    11041 ctatacagtc gttgagaaga ctcgaaaatc tctatctctc ctgcaacgtt tttggattac
    11101 tagtatcttt actgtgcctc ttgtgattct catgattggg atgttgacag gtagcattag
    11161 tcatcaagtc atgcattggg gaacctttct agcaacaacg cctattatgt tagttgcagg
    11221 taagccatat atccagagtg cttgggccag ttttaaaaag cacaatgcca acatggatac
    11281 cttggttgcg ctgggaactc tagtggctta tttctatagc ctagttgctc tctttgctgg
    11341 tctccctgtt tacttcgaaa gtgctggatt tatcctcttt ttcgttcttt tgggagcagt
    11401 ttttgaggaa aaaatgagaa aaaatacgtc ccaagctgtg gagaaattac tggacttgca
    11461 agctaaaacc gcagaagtct tgagtgatga tagttatgtc caagttcctt tggaacaagt
    11521 caaggtaggc gacctgattc gagtgcgtcc cggtgaaaag attgctgttg atggtgtcgt
    11581 agtagaaggt gtctctagta ttgacgaatc catggtgaca ggtgagagtc tgcctgtgga
    11641 caagacagtt ggagatactg tcattggctc aaccatcaat catagtggaa cgcttgtctt
    11701 tagagcagaa aaagttggct cagagactgt tttggctcag attgtggatt ttgtgaagaa
    11761 agctcagaca agtcgtgcgc cgattcagga cttgacggat aagatttcag ggatttttgt
    11821 cccagtagtt gtcattttag gaatcatgac cttttgggtt tggttcgtct tgctcaggga
    11881 tagtgtggtt gtgcttggag ctagctttgt gtcctctctt ctctacggag tggcggtttt
    11941 gattatcgcc tgtccttgtg ccttgggact tgcaacaccg acagccctta tggtggggac
    12001 aggacgtagt gccaagatgg gggttctcct caaaaatgga actgtcttac aggaaatcca
    12061 gaaagttcaa acccttgtct ttgataagac cgggactttg acggaaggga aacctgtggt
    12121 aacagatgtc atcggcgacg aagtagaagt gtttgggttg gcagcctcct tggaagatgc
    12181 ttctcaacac ccactggctg aggctatcgt taagcgagcg agtgaagctg gacttgagtt
    12241 tcaaactgtt gaaaattttc agaccttgca cgggaaaggt gtttcagggc gaatcaatgg
    12301 aaaacaagtt ttacttggaa atgctaaaat gctggatggc atggatattt ctaatactta
    12361 tcaagataaa ctagaagaac tagaaaaaga agctaagaca gttgtgttct tagctgttga
    12421 caatgaaatc aaaggcttgc ttgctttgca agatattcct aaggaaaatg ctaagctagc
    12481 catcagtcag ctaaaaaaac gtggtctccg aacagtcatg ctgacaggag acaatgctgg
    12541 tgtggcgcgt gctattgcag atcaaatcgg aattgaagag gtcattgcag gcgtcttgcc
    12601 agaagaaaaa gcccatgaaa tccataaact gcaacagtca gggaaagtag cctttgttgg
    12661 ggacggtatc aatgacgctc ctgcccttag tgtagcagat gtgggaattg ctatgggtgc
    12721 tggaacagat atcgccatcg agtcagcaga tttggtgttg acaaccaata atcttttagg
    12781 agtggttcgt gcctttgata tgagtaagaa aacctttcat cgaattctac tcaatctttt
    12841 ctgggctttt atctacaatg ttgtcggaat tccgattgca gcaggagtct tttcaggtgt
    12901 tggactggct ctcaacccag aattggcagg tctagccatg gcctttagtt ctgtatctgt
    12961 tctgaccagt tcccttctgt taaattttag taaaatagac taaaagtaat gactagattt
    13021 ctttgttata aaacagaaac gacaacactt tcaaaactgt attagaatag agaatagaga
    13081 gttttgagca gatttttaga aaagtcagca taaatatgat acagtggaat agtaaaaatt
    13141 tggagaacgt ttccaattct atgtaatcgt attctccaag tttaaaaaaa ttgaaggaga
    13201 gttatcatta tgactcaagg gaaaattact gcatctgcag caatgcttaa cgtattgaaa
    13261 acatggggcg tagatacaat ctacggtatc ccatcaggaa cactcagctc attgatggat
    13321 gctttggctg aagacaaaga tatccgtttc ttacaagttc gccacgaaga gacaggtgct
    13381 cttgcagcgg ttatgcaagc taaattcggc ggctcaatcg gggttgcagt tggttcaggt
    13441 ggtccaggtg cgactcactt gattaacggt gtttacgatg cagctatgga taacactcca
    13501 ttcctagcga tccttggatc acgtccagtt aacgaattga acatggatgc tttccaagag
    13561 cttaatcaaa acccaatgta caacggtatc gctgtttaca acaaacgtgt agcttacgct
    13621 gagcaattgc caaaagtaat tgacgaagcc tgccgtgctg cagtttctaa aaaaggtcca
    13681 gctgttgttg aaattccagt aaacttcggt ttccaagaaa tcgatgaaaa ctcatactac
    13741 ggttcaggtt catacgaacg ctcattcatc gctcctgctt tgaacgaagt tgaaatcgac
    13801 aaagctgttg aaatcttgaa caatgctgaa cgcccagtta tctatgctgg atttggtggt
    13861 gttaaagctg gtgaagtgat tactgaattg tcacgtaaaa tcaaagcacc aatcatcaca
    13921 actggtaaaa actttgaagc tttcgaatgg aactatgaag gtttgacagg ttctgcttac
    13981 cgtgttggtt ggaaaccagc caacgaagtg gtctttgaag cagacacagt tcttttcctt
    14041 ggttcaaact tcccattcgc tgaagtttac gaagcattca agaacactga aaaatttatc
    14101 caagtcgata tcgaccctta caaacttggt aaacgtcatg ctcttgacgc ttcaatcctt
    14161 ggtgatgctg gtcaagcagc taaagctatc cttgacaaag taaacccagt tgaatcaact
    14221 ccatggtggc gtgcaaacgt taagaacaac caaaactggc gtgattacat gaacaaactc
    14281 gaaggtaaaa ctgagggtga attgcaattg tatcaagttt acaatgcaat caacaaacat
    14341 gctgatcaag acgctatcta ctcaatcgac gtaggtaaca ctactcaaac atctactcgt
    14401 caccttcaca tgacacctaa gaacatgtgg cgtacatctc cactctttgc gacaatgggt
    14461 attgcccttc ctggtggtat cgctgctaag aaagacaatc cagatcgcca agtatggaac
    14521 atcatgggtg acggagcatt caacatgtgc tacccagacg ttatcacaaa cgttcaatac
    14581 gaccttccag ttatcaacct tgtcttctca aatgctgagt acggcttcat caagaacaaa
    14641 tacgaagata caaacaaaca cttgtttggt gtagacttca caaacgctga ctacgctaaa
    14701 attgcggaag ctcaaggagc tgttggattc acagttgacc gtatcgaaga catcgatgca
    14761 gttgttgcag aagctgttaa attgaacaaa gaaggtaaaa ctgttgtcat cgatgctcgc
    14821 atcactcaac accgtccact tccagtagaa gtacttgaat tggatccaaa acttcactca
    14881 gaagaagcta tcaaagcctt caaggaaaaa tacgaagcag aagaactcgt accattccgt
    14941 ctcttcttgg aagaagaagg attgcaatca cgcgcaatta aataattcct ctcgccgaaa
    15001 atcaaatatg aaacttgtag actttattct ttgattttca tagagcagaa ct
//
LOCUS       DAVKUR010000046        14827 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKUR010000046 DAVKUR010000000
VERSION     DAVKUR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.046"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            577..2256
                     /locus_tag="VW749_001630"
     CDS             577..2256
                     /locus_tag="VW749_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0175642.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGSNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(2296..4380)
                     /locus_tag="VW749_001631"
     CDS             complement(2296..4380)
                     /locus_tag="VW749_001631"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0175643.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            4551..5831
                     /locus_tag="VW749_001632"
     CDS             4551..5831
                     /locus_tag="VW749_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0175644.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            5922..8567
                     /locus_tag="VW749_001633"
     CDS             5922..8567
                     /locus_tag="VW749_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0175645.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            8651..9520
                     /locus_tag="VW749_001634"
     CDS             8651..9520
                     /locus_tag="VW749_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0175646.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            9514..11394
                     /locus_tag="VW749_001635"
     CDS             9514..11394
                     /locus_tag="VW749_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0175647.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            11685..12047
                     /locus_tag="VW749_001636"
     CDS             11685..12047
                     /locus_tag="VW749_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175648.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(12099..12948)
                     /locus_tag="VW749_001637"
                     /pseudo
     CDS             complement(12099..12948)
                     /locus_tag="VW749_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(12893..13075)
                     /locus_tag="VW749_001638"
     CDS             complement(12893..13075)
                     /locus_tag="VW749_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0175649.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            13410..>14827
                     /gene="pcpA"
                     /locus_tag="VW749_001639"
     CDS             13410..>14827
                     /gene="pcpA"
                     /locus_tag="VW749_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0175650.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGVVGWVKDKGLW"
BASE COUNT         4349 a         2887 c         3383 g         4208 t
ORIGIN      
        1 aaatgcataa acttctataa aaaggatata aaattttttt aaaaaatttt tcaaaaaata
       61 tacaaatgac caaaaagtgt ccaattatca tctggttatc acttggatct gtataaagag
      121 aaatgtttgt gtgaaaggat aaaaagatgc aacattcttt tgaagataga ttttggagaa
      181 gcatttcttg ttcaattgta caaattatag aatcttttct gagtatttag gaagagataa
      241 ttatcttatt gaccctcttt ttattttttg ttatagtcga cgaggtgata gtttagaata
      301 atcacttatt cacaatctgt ggaaaagtct ggagagtgaa tggtcttcac acaatgacct
      361 gaaagaagcc tgagaataat tatggagagt agcattctga gaggtgttag cagaaccata
      421 tgacagagct gtttgaagag ggaatattga ggagaaaaat cctgagccta ccagttggag
      481 ttggaaagag ctggctgtta gatcatggtt tattatccac aacctgtgga taaccttgtg
      541 aacaagagaa gttgctaaag aaggagatat ataacgatga agaaaatcaa accgcatgga
      601 ccgttaccaa gtcagactca gctagcttat ctgggagatg aactagcagc ttttatccac
      661 ttcggttcta atacctttta tgaccaagaa tgggggactg gacaggagga tcctgagcgc
      721 tttaacccga gtcagttgga tgcgcgtgag tgggttcgtg tgctcaagga aacgggcttc
      781 aaaaagttga ttttggtggt caagcaccac gatggctttg tcctttatcc gacagctcac
      841 acagattatt cggttaaggt cagtccttgg aggagaggaa agggcgactt gctccttgaa
      901 gtatcccaag ctgccacaga gtttgatatg gatatggggg tctacctgtc accgtgggat
      961 gcccatagtc ccctctatca tgtggaccga gaagcggact acaatgccta ttatctggct
     1021 cagttgaagg aaatcttatc aaatcctaac tatgggaatg ctggtaagtt cgctgaggtt
     1081 tggatggatg gtgccagagg agagggcgcg caaaaggtta attatgaatt tgaaaaatgg
     1141 tttgaaacca ttcgtgacct gcagggcgct tgcttgattt tttcaacaga aggcaccagt
     1201 atccgctgga ttggcaatga acgagggtat gcaggtgatc cactgtggca aaaggtgaat
     1261 cctgataaac taggaacaga agcagagctg aactatcttc agcacgggga tccctcgggc
     1321 acgatttttt caatcggaga ggcagatgtt tccatccgtc caggctggtt ctaccatgag
     1381 gatcaggatc ctaagtctct cgaggagttg gtcgaaatct actttcactc agtagggcga
     1441 ggaactccac tcttgcttaa tattccgccg aatcaagctg ggctctttga tgcaaaggat
     1501 attgaacgac tttatgaatt tgcgacctat cgcaatgagc tctataaaga agatttggct
     1561 ctgggagctg aggtatctgg tccagctctt tccgcagact ttgcttgtcg ccatttgaca
     1621 gacggccttg agaccagctc ttgggcaagc gatgcagact tgcccatcca gttagaactc
     1681 gacttaggtt ctcctaaaac ttttgatgta attgagttaa gagaagattt gaagctaggg
     1741 caacgaatcg ctgcttttca tgtgcaagta gaggtggatg gtgtctggca ggagtttggt
     1801 tcgggtcata ctgttggtta caaacgtctc ttacgaggag cagttgttga agcacagaag
     1861 atacgtgtag tcattacaga atcacaggct ttgcctttgt tgaccaagat ttcactctat
     1921 aaaactccga ggttatcaca aacagtagct gttcaggggc tagcatttgc agaaaaaagc
     1981 ctagctgtgg caaagggaga gactcttcat tttaggattg aacgtagtga aagtagctcc
     2041 tctttagagg ctaagatttc gattcaaccg gggacaggtg tccatggtgt cgcctatcag
     2101 gatgagattc aagtccttca attccaagca ggggaaagca aaaaagattt gcatctacca
     2161 accctgtatt tcgcaggaga taaaaccttg gatttctatc tgaacctaac ggtggatggt
     2221 cagcttgtgg atcaacttca agtccaagtt tcataaaaga agaacctttg cgcgatgcaa
     2281 aggttctttt ggttattagt gacttggtaa ccagctgagg gtgaaagtta gttgttcagc
     2341 ttttaagagg tcttggtgtt gaatagttga tacgagtgtt ttgtccagtc ggcattcttt
     2401 gacaaagtta aaatggttgt ggttttgttt agtatggata tccagccatt tatcttcttt
     2461 agcgaggtag actcgtagat ggtcaaagag agggattccg aggtcatagc ttggttttcc
     2521 tggacaggtt ggataaaatc cgagagctga ccagatgtac caagcagaga gactaccatt
     2581 gtcttcatct ccaggatagg cttcccaact tgggtgaaaa gctttctgac ggagcgtctt
     2641 gataagaagg gcagtgtagt cagggtaatc gctgtagcgg aagagataag gaatgtggaa
     2701 actaggctgg ttggaaatgg ctatttgtcc aaaaggagca gtagccatct cgctcatttc
     2761 gtgaatttcg taaccatagc ctgttgtttc aaagagggga gcatcttgac aggctttcaa
     2821 aagatagttg ctaaaggttt cttttccacc catcagttgg attaagccag ggatgtcgtg
     2881 gagaacgcct aaagtagctt gaatggcaga gcattcagcg tagtctcgcc cccaactata
     2941 aggagagaag tcagggtgaa agtttccttg attgtctcgt gctcgcatgt aacctgtctc
     3001 agcgtcaaat agctggcggt aattttgtga agcagccttg taggtttcag cgatttctat
     3061 gttctctagt tttttggcac agctggcgat acaaaagtca ctataggcat agtctagagt
     3121 atggctaaca ctttcgtggt ggtcggtaga gaggtaacct agttcttggt attgggctag
     3181 tccgtggcgg ccattgattc cgagagggtc ggctttgctg gctgtttcga gcatggcttg
     3241 gaagagttct ccttctaggt caggggccat gtccttgcag gcgctatctg cgataatacc
     3301 gtctaaaagt gtacctggca tcataccccg ttcatctgga gccagccatt ttggaaggaa
     3361 accagtatcg cggtagctat tgaggaaacc ttctaaaaag cgttgatagt gctccggtat
     3421 gataagggca aagaggggga aggtggtgcg gaaggtatcc cagaaaccat tgttgctaaa
     3481 gaggacacca ggcttgacag taccagtagc cagatccatg tggatggctt gccctgactc
     3541 atcaacctca taaaaagtct gtgggaagag gaagagtctg tagaggcagt ggtcaaagaa
     3601 ggttcggtca gcctctcctg tctctataat gtcaaaacga tggaggagat tttcccaatc
     3661 cgcttgggca cttgctttac agctatcaaa atcttcttga ggtagattaa gcagtgcttg
     3721 agaaggagag atgaaagaag tggctagttg catctcggtt tgactacttg ctaagtcaat
     3781 tcgccagtcc ccagcttctt ggctgatagc aagaatatcc gtgttcattt gcagggcagt
     3841 gaacatcgtt agcgaatttt tgttggtttc agttttacct tcttgtcgca gggcaagagt
     3901 tcgcttatct acttgctcta ctgtcagttc atctgttgcg tgaagataga gggagagggc
     3961 tttgccttgc ttttgcttca aacgaataga agcaccgtag caagtcggtg tgagctgggt
     4021 ttcaatctga taacgcagag aaaagagctt caaatagtga ggctggaagc aagctttatc
     4081 tatatcataa gaagactggc ggtgaaagag gctgtctccc cccagttgac tggtgacagg
     4141 tgtcagaagg agccaagagt agtccccaat ccaaggactg ggctggtgag ttaatcgaat
     4201 cccctgaaag ataggcagat gcggatcaaa aaaccaagat ccatcctggt cactggtctg
     4261 gggcacaaag taattcatcc caaaaggcac gcctgtgtat ggcagggtat ttccccaaga
     4321 gaaggcatgc ttgctagcag taccaaagcg ggtatcgatg gtttcaagta gtggtttcat
     4381 agtctttcct ttagctgttt ttctacatta tatcagaaaa agagggactt tagaaaagga
     4441 gtttcaaaaa taactatttt gtagaaaaat gactatcatt tgtgtatgta ttttctgtct
     4501 caaaagctat atactgaaca tgaaacttgt ttgaaagagg gaattgcacg atgatttatt
     4561 cgaaagaaat tgttagagaa tggctagatg aagtagcaga gcgggctaag gaccatccag
     4621 agtgggtgga tgttttcgag cgttgctaca ccgatacctt ggacaatacg gttgaaatct
     4681 tagaagatgg ttcaactttt gtcttgactg gggatattcc tgctatgtgg cttcgggatt
     4741 cgacagccca gctcagaccc tacctgcatg tagctaaaag agatgccctc ctgcgtcaga
     4801 ccattgcagg tttggtcaaa cgtcagatga ccttggtact caaggatcct tatgccaatt
     4861 ccttcaacat agaggaaaac tggaaggggc accacgagac cgaccacacc gaccttaatg
     4921 gctggatttg ggaacgcaag tatgaggtgg actcgctttg ctatcctttg cagttggctt
     4981 atctcctctg gaaagaaact ggcgagacta gtcagtttga tgagactttt gtcgcagcga
     5041 ctaaggaaat tctccatcta tggacagttg aacaagacca caagaactct ccttatcgtt
     5101 ttgtccgaga tacggaccgt aaggaagaca ccttggtaaa tgatggcttt ggacctgact
     5161 ttgcagtgac aggtatgact tggtcagcct ttcgtccgag tgatgactgt tgccagtata
     5221 gttacttgat tccgtcaaat atgtttgctg tagtagtctt gggttatgtg caagaaatct
     5281 tcgcagcatt aaacctagct gatagccaga gtgttattgc tgatgccaag cgtcttcagg
     5341 atgaaatcca agaaggaatc gaaaactacg cttacaccac caacagtaag ggtgaaaaga
     5401 tttatgcctt tgaagtggat ggcctaggaa atgccagcat tatggatgat ccaaacgtac
     5461 caagtctact agctgcgccc tatctgggct actgttcggt cgatgatgaa gtgtatcaag
     5521 ctactcgccg taccattctg agctctgaaa atccatattt ctaccaagga gaatacgcta
     5581 gcggtcttgg aagttctcat accttctatc gctatatctg gccaatcgcc ctttctatcc
     5641 aaggcttgac aacaagagat aaggcagaga aaaacttctt gctggatcag ctggttgcct
     5701 gcgatggcgg tacaggtctt atgcatgaaa gcttccacgt ggatgaccca actctctact
     5761 ctcgtgaatg gttctcctgg gctaacatga tgttctgtga gttggtcttg gattacttgg
     5821 atattcgcta aggggctcgc tttagctcaa ccgattctta tcagaatcac aagtttacat
     5881 ttaaaacgtt aaaatttaaa tttagaatga ggttttactt catggaaaat gttgttgtac
     5941 atattatctc acatagtcac tgggaccgtg agtggtactt gccttttgaa agtcatcgta
     6001 tgcagttggt ggaattgttt gacaatctct ttgatctctt tgaaaatgac cctgagttca
     6061 agagtttcca cttggatgga caaactattg tccttgacga ctacttacaa attcgccctg
     6121 aaaatcgcga caaggtccaa cgctacattg acgagggcaa gcttaaaatt ggtccctttt
     6181 acatcttgca ggatgattat ttgatttcaa gtgaagccaa tgtccgcaat accttgattg
     6241 gtcaacaaga agctgccaaa tggggtaaat caacccagat tggctacttt ccagatacct
     6301 ttggaaatat gggacaagca cctcaaattc ttcaaaaatc aggcattcat gtggcggcct
     6361 ttggtcgtgg tgtgaagccg attggatttg acaaccaagt ccttgaagat gagcagttta
     6421 catcccagtt ttcagaaatg tactggcagg gtgtggatgg tagtcgtgtt ttaggtattc
     6481 tctttgccaa ctggtacagt aatgggaatg aaatcccagt tgacaaagat gaggccttga
     6541 ccttctggaa acaaaaattg tcagatgtgc gtgcctacgc ttcgaccaac caatggttga
     6601 tgatgaacgg ctgtgaccac cagcctgtac agaaaaatct gagcgaagcc attcgtgtgg
     6661 caaatgaact cttcccggat gtaatctttg ttcatagttc ttttgatgaa tatgttcaag
     6721 ctgtagaagg tgcgcttcct gaacacttat caactgttac aggcgagttg accagtcagg
     6781 aaacagatgg ctggtacaca cttgccaaca cttcttcatc ccgcatttac ctgaaacaag
     6841 ccttccaaga aaatagcaac ctcctagagc aagtggtaga acccttgact attatcactg
     6901 gtggacacaa ccacaaggac cagttgacct atgcttggaa aacacttttg cagaacgcgc
     6961 cacatgatag tatctgtggc tgtagcgtgg acgaagttca ccgcgagatg gaaacgcgtt
     7021 ttgccaaggt caaccaagta ggaaactttg ttaaaagtaa cttgctcaac gagtggaagg
     7081 gtaaaattgc tacggataag gctcaaagtg actatctctt tactgtcatt aacacaggct
     7141 tgcatgataa ggtcgatact gtcagcacag tgattgatgt ggcgacttgt gatttcaagg
     7201 aattgcaccc aacagaaggc tacaaaaaga tggctgctct tatcttgcca agttaccgtg
     7261 tggaggactt ggatggtcgt cctgtagagg ctacaatcga agacctcgga gctaattttg
     7321 agtacgattt accaaaagat aagttccgcc aagctcgtat tgctcgacaa gtgcgcgtga
     7381 ccattccagt tcacctagcg ccgctttctt ggacaacctt ccaattgctg gaaggaaaac
     7441 aagaacaccg tgagggtatt taccaaaacg gagtgattga tacaccattc gtaacggtga
     7501 gtgtggatga caacatcaca gtctatgaca agacaactca cgaagcctat gaagacttta
     7561 tccgctttga agaccggggt gacatcggaa acgagtatat ctatttccaa ccaaaaggaa
     7621 cagagccaat ctttgcagag cttaagggcc acgaggtctt ggaaaacaca gatcgctatg
     7681 ctaaaatctt gctcaaacat gaattgaccg tgcctgtcag tgcggatgaa aagctagaag
     7741 aagagcaaca aggtatcatc gagtttatga agcgtgaggc tggacggtca gaagaattga
     7801 caaacattcc tctggaaact gagttgattg tctttgttga caatccacaa atccgcttca
     7861 agactcgctt tactaacact gccaaggatc accgtatccg tctcttggtc aagactcata
     7921 acacgcgtcc aagcaatgat tctgaaagta tctatgaggt ggtgacacga ccaaacaaac
     7981 cagctgcttc atgggaaaat cctgaaaatc ctcaacacca acaagctttt gtcagtctgt
     8041 atgacgatga aaaaggggtg actgtatcca acaagggatt gaatgaatac gaaatccttg
     8101 gggataacac cattgccgtg accattttgc gtgcatcagg tgagctaggt gactggggct
     8161 acttcccaac gccagaagca caatgcttgc gtgagtttga agtcgaattt gcgattgaat
     8221 gccaccaagc ccaagaacgc ttctcagcct atcgtcgtgc caaagccttg cagacaccgt
     8281 ttaccagcct tcagcttgct agacaggaag gaagcgtggt tgcgactggt agcctcttga
     8341 gccattctgt tctcagcata ccgcaagttt gtccaacagc ctttaaagtg gcggaaaatg
     8401 aagaaggcta tgtcctccgt tactataata tgagtcaaga aaatgtgcgc atatcagaac
     8461 atcaacaaac cattcttgac ttacttgagc gaccatatcc agttcattca ggactattgg
     8521 ctccacaaga gattcgtaca gaattcatca aaaaagaaga aatttaattt caaaaagtaa
     8581 acatcaaaag aaaggagggg cgaaaaagta agaactaact gctgattcgc ccctttttat
     8641 ggtaaaaaca atgaccattg caacgattga tatcggaggg actgggatta agtttgccag
     8701 tctgactcct gatgggaaaa tactggataa gacaagtatt tcaacgcctg aaaacttgga
     8761 ggatttacta gcgtggctag atcaacgctt gtcagaacag gattacagtg ggattgctat
     8821 gagtgttcca ggtgcagtca atcaagagac aggtgtgatt gatggcttca gtgcggtgcc
     8881 ctacatccat ggcttttctt ggtatgaggc gcttagctct tatcagctac ctgtccattt
     8941 agaaaatgat gccaactgcg ttggactcag tgaactacta gctcatccag agcttgaaaa
     9001 tgcagcctgt gtcgtgattg ggacagggat tggcggagcc atgattatca atggtagact
     9061 tcatcgaggt cgccacggtc tgggtggaga atttggctac atgacaaccc ttgcccctgc
     9121 tgaaaaactt aataactggt cgcaactagc atcaactggg aatatggtac gatacgtgat
     9181 tgaaaaatct ggtcatactg attgggacgg tcgcaagatt taccaagagg ccgcagctgg
     9241 taatgctctt tgtcaagaag ccattgagcg catgaaccgc aatttgacgc aaggcttgct
     9301 caatatccag tatctcatcg atccagatgt catcagtctg ggtggctcta tcagtcaaaa
     9361 tccagatttt atccaaggtg ttaagaaggc tgttgaagac tttgtcgatg cctacgaaga
     9421 atacacggtc gcaccagtta tccaggcctg cacctatcac gcagatgcca atctctacgg
     9481 tgctcttgtc aactggctac aggaggaaaa gcagtggtaa gatttatagg acttagtccc
     9541 aaacaaacgc aagctattga ggttttaaaa ggtcacattt ctctaccaga tgtggaagtg
     9601 gctgtcactc agtctgacca agcatctatc tctatccagg gtgaggaagg tcactatcaa
     9661 ttgacctatc gcaaacctca ccaactttat cgtgccttgt ccttgttggt aacagttcta
     9721 gcagaagctg ataaagtaga gattgaggaa caagcagctt acgaagattt ggcttacatg
     9781 gttgactgtt ctcgaaatgc ggtgctgaat gtggcttctg ccaagcagat gattgaggtc
     9841 ttggctctca tgggctactc aacctttgag ctttacatgg aagacactta ccagattgaa
     9901 ggacagcctt actttggcta tttccgtgga gcttattcag cagaggagtt gcaggaaatc
     9961 gaagcctatg cccaacagtt tgacatgacc tttgtaccat gcatccagac cttggcccac
    10021 ttgtcggcct ttgtcaaatg gggtgtcaag gaagtgcagg agctccgtga tgtagaggac
    10081 attcttctca ttggcgaaga aaaggtttat gacctgattg atggcatgtt tgccacgttg
    10141 tctaaactga agactcgcaa ggtcaatatc gggatggacg aagcccactt ggttggtttg
    10201 ggacgctacc tgattttgaa cggtgttgtg gatcgtagtc tcctcatgtg ccaacacttg
    10261 gagcgcgtgc tggatattgc tgacaaatat ggtttccact gccagatgtg gagtgatatg
    10321 ttcttcaaac tcatgtcagc ggatggccag tacgaccgtg atgtggaaat tccagaggaa
    10381 actcgtgtct acctagaccg tctcaaagac cgtgtgactc tggtttactg ggattattat
    10441 caggatagcg aggaaaaata caaccgtaat ttccgcaatc atcacaagat tagccatgac
    10501 cttgcatttg cagggggagc ttggaagtgg attggcttta cacctcacaa ccattttagc
    10561 cgtctagtgg ctatcgaggc taataaagcc tgccgtgcca atcagattaa agaagtcatc
    10621 gtaacgggtt ggggagacaa tgggggtgaa actgcccagt tctctatcct accaagcttg
    10681 caaatctggg cagaactcag ctatcgccat gacctagata gtttgtctgc gcacttcaag
    10741 accaatactg gtctaacggt tgaggatttt atgcagattg accttgccaa cctcttacca
    10801 gacctaccag gcaatctcag tggcatcaat cccaaccgat atgtctttta tcaggatgtt
    10861 ctctgtccga tacttgaccg acacatgaca cctgaacagg acaaaccgca cttcgctcag
    10921 gctgctgaga cgcttgctaa cattaaagaa aaagctggaa actatgctta tctctttgaa
    10981 actcaggccc agttgaatgc tattttaagt agcaaagtag atgtgggacg acgcattcgt
    11041 caggcctacc aagcggatga taaagaaagt ttacaacaaa tcgccagaca agaattacca
    11101 gaacttagaa gccaaattga agacttccat gccctcttta gtcaccaatg gctgaaagaa
    11161 aacaaggtct ttggtttgga tacagttgac atccgtatgg gcggactctt gcaacgcatc
    11221 aaacgagcag aaagccgtat cgaggtttat ctggctggcc agcttgaccg catcgacgag
    11281 ctggaagttg aaatcctacc atttactgac ttctacgcag acaaggattt cgcagcaact
    11341 acagctaacc agtggcatac cattgcgaca gcttcgacga tttatacgac ttaatactct
    11401 tcgaaaatct cttcaaacca cgtcagcttc catctacaac ctcaaaacag tgttttgagc
    11461 agcctgcagc tagcttccta gtttgctctt tgattttcat tgagtataaa aacaagaaca
    11521 ccttgcttgg cgcagggtgt ttcgcgtgaa acagaagaat tatctggttt caaatgctac
    11581 agttaaaatt agtaaaacaa gaaatagaag ctgaaaagcc agcatctgta gaggcttgga
    11641 tcatttccgt caaatttaaa aaaggttgct accgacatat atagattcca aaaacaaaaa
    11701 cgttagcgga actagcagat gtgattttat ggagttttga ttttgcaaat gatcatgctc
    11761 acgcattttt catggataat attgagtgga gtcatgcaga ttcttacttt cttagctttg
    11821 ttagtgacga tgttgaagaa cgttacacag aaaatgtcta tctggatagc ctaagtgtca
    11881 aacaaaaatt taagtttatt ttcgacttcg gtgatgaatg gcgttttgaa tgccaagtgc
    11941 tgagagaaat cgagacagag gacgaagaag cttatctcgt acgttcggtt ggaacgtcgc
    12001 cagaacaata tccagattat gatggttttg actatgaaga atggtaaaat tgaaatcagt
    12061 ctgtgtaggc ttagtatttc aatagacttc ctgcaaaact agaatcctag ttcatgattg
    12121 ataataccag caatcaaatt cattcgtaat ccgaagcgtt tacgatgatt tcgataggtt
    12181 gttgaaaaca ttttaaacgt ttttactttg gcaaagatgt tctcaacctt gcttctctcc
    12241 ttggatagcg catggttata ggctttatct tcagctgtta gtggcttgag tttgctggat
    12301 ttacgtgaag tttgtgcttg aggacatatc ttcatgagcc cttgataacc actgtcagcc
    12361 aagattttac caacttgtct gatatttctg caactcattt tgaacaactt catatcatga
    12421 caatagttca cagtgatatc caaagaaaca attctccctt gacttgtgac aatcgcttga
    12481 gccttcatag cgtgaaattt ctttttacca gaatgattcg ctaattgttt ttttagggcg
    12541 attgatttgt acttccgtcg catcaatcat taccgtgtcc tcagagctga gaggagttct
    12601 tgaaatcgta acaccacttt gaacaagagt tacttcaacc cattggctcc gacggattaa
    12661 gttgctttcg tggataccaa aatcagccgc aatttcttca taagtgcggt attctcacac
    12721 atattgaaga gtggccataa gaaggtcttc taggcttaat ttaggttttc gtccaccttt
    12781 tgcgtgttta agttgataag ctgtttttaa tacagctaac atctctttaa aagtcgtgcg
    12841 ctgaacacca acaagacgct taaatcgtgt atcagttaat tgtttacttg cttcataatt
    12901 tcgcagggag tctattgact ctttggtagg tgtcaatgtt tttttcatct atcccgagaa
    12961 ttattttccc gccatttgta tttgcaaatg ctgagtaggt ttcccagaaa gactctggaa
    13021 gattgttttt agcttttttg tattctaaat caaccccttc aaattttaag tccatatttt
    13081 tcctttacat ctgttttttg tggttctggt atttgttcaa gttgagtgat aatatagcga
    13141 attgaatttc gagagttttt actcagttaa tttctttttt aacccacttt aatttctttt
    13201 ttaacacggg ttaaaaaaga aattaaagtg ggttaatttt ccttgactta aaatttaaaa
    13261 atgatatact gtgtttatgg agagatgaca atttataaaa tgtactactc tattctacta
    13321 gataatgatt gaataaaact ttttataaca acggctagca aagttataat tttatatcta
    13381 ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac tacaatatta tcattaacta
    13441 cagctgcggt tattttagca gcatatgtcc ctaatgaacc aatcctagca gatactccta
    13501 gttcggaagt aatcaaagag actaaagttg gaagtattat tcaacaaaat aatatcaaat
    13561 ataaggttct aactgtagaa ggtaacatag gaactgttca agtgggtaat ggagttactc
    13621 ctgtagagtt tgaagctggt caagatggaa aaccattcac gattcctaca aaaatcacag
    13681 taggtgataa agtatttacc gttactgaag tagctagtca agcttttagt tattatccag
    13741 atgaaacagg tagaattgtc tactatccta gctctattac tatcccatca agcataaaaa
    13801 aaatacaaaa aaaaggcttc catggaagta aagctaaaac tattattttt gacaaaggca
    13861 gtcagctgga gaaaattgaa gatagagctt ttgatttttc tgaattagaa gagattgaat
    13921 tgcctgcatc tctagaatat attggaacaa gtgcattttc ttttagtcaa aaattgaaaa
    13981 agctaacctt ttcctcaagt tcaaaattag aattaatatc acatgaggct tttgctaatt
    14041 tatcaaattt agagaaacta acattaccaa aatcggttaa aacattagga agtaatctat
    14101 ttagactcac tactagctta aaacatgttg atgttgaaga aggaaatgaa tcgtttgcct
    14161 cagttgatgg tgttttgttt tcaaaagata aaactcaatt aatttattat ccaagtcaaa
    14221 aaaatgacga aagttataaa acgcctaaag agacaaaaga acttgcatca tattcgttta
    14281 ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg tttagaaaaa atcggtactt
    14341 ttgcatttgc ggatgcgatt aaacttgaag aaattagctt accaaatagt ttagaaacta
    14401 ttgaacgttt agccttttac ggtaatttag aattaaaaga acttatatta ccagataatg
    14461 ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa attaaaaagt ttaacaattg
    14521 gtaataatat caactcattg ccgtccttct tcctaagtgg cgtcttagat tcattaaagg
    14581 aaattcatat taagaataaa agtacagagt tttctgtgaa aaaagataca tttgcaattc
    14641 ctgaaactgt taagttctat gtaacatcag aacatataaa agatgttctt aaatcaaatt
    14701 tatctactag taatgatatc attgttgaaa aagtagataa tataaaacaa gaaactgatg
    14761 tagctaaacc taaaaagaat tctaatcggg gagtagttgg ttgggttaaa gacaaaggtt
    14821 tatggta
//
LOCUS       DAVKUR010000047        14443 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKUR010000047 DAVKUR010000000
VERSION     DAVKUR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.047"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            81..878
                     /locus_tag="VW749_001640"
     CDS             81..878
                     /locus_tag="VW749_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0175651.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VW749_001641"
     CDS             1026..1148
                     /locus_tag="VW749_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV0175652.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            1170..2285
                     /locus_tag="VW749_001642"
     CDS             1170..2285
                     /locus_tag="VW749_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0175653.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGSSCHNLSYIRDVGAATFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPNQIRLSIGLENVEDLIEDLRLALEKI"
     gene            2381..3655
                     /locus_tag="VW749_001643"
     CDS             2381..3655
                     /locus_tag="VW749_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0175654.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VW749_001644"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VW749_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0175655.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VW749_001645"
     CDS             4784..5086
                     /locus_tag="VW749_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0175656.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VW749_001646"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VW749_001646"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0175657.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VW749_001647"
     CDS             5960..7300
                     /locus_tag="VW749_001647"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0175658.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VW749_001648"
     CDS             7278..7490
                     /locus_tag="VW749_001648"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0175659.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VW749_001649"
     CDS             7487..8362
                     /locus_tag="VW749_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0175660.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VW749_001650"
     CDS             8355..9170
                     /locus_tag="VW749_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0175661.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VW749_001651"
     CDS             9163..9594
                     /locus_tag="VW749_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0175662.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VW749_001652"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VW749_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0175663.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VW749_001653"
     CDS             11270..11998
                     /locus_tag="VW749_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0175664.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VW749_001654"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VW749_001654"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0175665.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14194..14274)
                     /locus_tag="VW749_001655"
                     /pseudo
     CDS             complement(14194..14274)
                     /locus_tag="VW749_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4292 a         2627 c         3410 g         4114 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atgatttctt cagaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatat
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggatcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac tcgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgtga
     1081 ctccagctac tgagtctcgt gcagtgccga tttatcaaac aacatctttt gtttttgatg
     1141 acacgtagga aggtgctgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatattgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaactc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt tcaagctgcc
     1741 acaatttgag ctatattcgt gatgtgggtg cagcaacctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac tctttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tgacgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaaccaa attcgtctgt
     2221 caatcggtct tgaaaatgta gaagatttga ttgaagactt acgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggtt ttgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttacaga agtctagaaa gaggaatgta atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga aagccagtat gctgaacttt tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aggcaggaac tggccttggc
     2521 tgagcaaaag gctatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt
     2641 tgaacagaca agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa
     2701 tcagttggct accttgcgtt tggagcatga aaatcaacta caaaagaccc tttctgacct
     2761 agaaaaagaa cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt
     2821 atctttggct tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagatttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgaccac
     3541 atctgaaaac caactccgtt tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatta acttaaaaaa ggaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aatcactctg ggctattcca cgaagactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctctcttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattact cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggacgt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctgatgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aatcggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg aacctcaaga tgtctttatc
     5521 gttgagggta ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgcatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc tgccccaatt
     6361 ttctaagaga attggtgtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atggtaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttaccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttagagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ctttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttgggacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgttaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attaccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgtacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagcc atgaatgaca tggaaagtgt cgaagagtat
    10381 gaccctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctcatg
    10501 caggttgaga atcgtttgca cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttca ttttagtaag
    10801 ggaaaattca gtcgtggggg aaatgaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acagtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc ttaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcgtcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atatttgttc acgcaggtat
    11701 tgatttgact ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacagggga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg gaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagagcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttatccagg aacgtttaga gcgtgagttc aatattgatc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaatcgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagtttt gactacgaat tgtcagaata tcgcccatct aagctagtga aaatggatat
    13561 ccttctcaac ggagacaagg tggatgccct cagctttatc gttcataagg actttgctta
    13621 tgaacgtggg aaactcatcg ttgataagct caagaaaatc atccctcgcc aacaatttga
    13681 ggttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taagaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aatctcaaaa ccatgttttg agctgacttc
    14101 gtcagtttca tctacaacct caaaaccatg ttttgagctg acttcgtcag tttcatctac
    14161 aacctcaaaa ccatgttttg agctgacttc gtcagtttca tctacaacct caaaactgtg
    14221 ttttgagtaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtattagaa
    14281 cagaaaaatg cttggagtat ttgtttgtgt gtttattttt atataacaaa ctataaacac
    14341 aacaaaaata taaaaaaaga gacaaaaaag aacagaaagt aattaacaac gatttcatat
    14401 agtgttatac ttatagcata aagttaatgg aaagaaggga aaa
//
LOCUS       DAVKUR010000048        14077 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKUR010000048 DAVKUR010000000
VERSION     DAVKUR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.048"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(28..837)
                     /locus_tag="VW749_001656"
     CDS             complement(28..837)
                     /locus_tag="VW749_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0175666.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            complement(839..2188)
                     /gene="vicK"
                     /locus_tag="VW749_001657"
     CDS             complement(839..2188)
                     /gene="vicK"
                     /locus_tag="VW749_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0175667.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            complement(2181..2885)
                     /locus_tag="VW749_001658"
     CDS             complement(2181..2885)
                     /locus_tag="VW749_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175668.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            complement(2940..4115)
                     /gene="mutY"
                     /locus_tag="VW749_001659"
     CDS             complement(2940..4115)
                     /gene="mutY"
                     /locus_tag="VW749_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0175669.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            complement(4443..6113)
                     /locus_tag="VW749_001660"
     CDS             complement(4443..6113)
                     /locus_tag="VW749_001660"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0175670.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            6343..7032
                     /gene="coaB"
                     /locus_tag="VW749_001661"
     CDS             6343..7032
                     /gene="coaB"
                     /locus_tag="VW749_001661"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0175671.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7044..7595
                     /gene="coaC"
                     /locus_tag="VW749_001662"
     CDS             7044..7595
                     /gene="coaC"
                     /locus_tag="VW749_001662"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0175672.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            7579..8142
                     /locus_tag="VW749_001663"
     CDS             7579..8142
                     /locus_tag="VW749_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0175673.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            8424..8951
                     /locus_tag="VW749_001664"
     CDS             8424..8951
                     /locus_tag="VW749_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0175674.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            8963..9478
                     /locus_tag="VW749_001665"
     CDS             8963..9478
                     /locus_tag="VW749_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0175675.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(9475..9942)
                     /locus_tag="VW749_001666"
     CDS             complement(9475..9942)
                     /locus_tag="VW749_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0175676.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(10016..10504)
                     /locus_tag="VW749_001667"
     CDS             complement(10016..10504)
                     /locus_tag="VW749_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175677.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(10470..11033)
                     /locus_tag="VW749_001668"
     CDS             complement(10470..11033)
                     /locus_tag="VW749_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175678.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(11043..13031)
                     /gene="uvrB"
                     /locus_tag="VW749_001669"
     CDS             complement(11043..13031)
                     /gene="uvrB"
                     /locus_tag="VW749_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0175679.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(13108..14061)
                     /locus_tag="VW749_001670"
     CDS             complement(13108..14061)
                     /locus_tag="VW749_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175680.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
BASE COUNT         4156 a         3185 c         2527 g         4209 t
ORIGIN      
        1 aaaaagaaca ccttctcagc gttctttcta tatctctgtc aatggtgttg cggtatctgg
       61 tgaggtatca taaaccttaa agtctactcc gactcccaga tcagcttgag ccagctgatt
      121 gaccatggtc atatgagcca gttccttgat attgttttcc ttagataaat gcccaaggta
      181 aatcttctta gtacgatttc ctagcgtccg aatcatagct tcagcaccgt cctcgttaga
      241 aaggtgacca aggtcagata ggattcgttg tttgagtcgc caagcgtaag aacctgatcg
      301 caaaatctct acatcatggt tggcctcgat aagataacca tccgcatttt cgacaatgcc
      361 cgccatacgg tcactgacat aacctgtatc tgtcaagagg acaaaactct tatcatcctt
      421 cataaagcga tagaactgcg gtgcgactgc atcatggctt acaccaaaac tctcgatgtc
      481 gatatctcca aaggttttgg ttttacccat ttcaaaaata tgcttttgcg aagaatccac
      541 cttgccaaga tatttactat tttccatagc ttgccaggtc ttttcattgg cataaagatc
      601 cataccatac ttgcgagcca aaacgcctac tccatggata tgatctgaat gctcatgggt
      661 aatcaagatg gcatccaggt cttctggctt acggttaatt tcagctagca gactggtaat
      721 tttcttgcca gacaagcctg catctactaa aagcttcttt tttgaggttt ccagataaaa
      781 agaatttcca ctggaacccg acgctaaaat actgtattta aagcctattt cactcattct
      841 agtcttctac ttcatcctcc catacttctt ctttcactgc atccttatca taagggagta
      901 caatggtaaa ggttgaaccc ttgccgtatt cactcttggc ccaaataaag cccttatgtt
      961 gtttgataat ttctttagcg atagacagtc ctagacctgt accaccttgt gcacgacttc
     1021 tagcacgatc cacacgatag aaacggtcaa agatacgtgg taaatcctgc ttaggaatcc
     1081 ccaaaccgtg gtcagaaatg gataaaatca tctggtcttc agttgtcttc attctgacag
     1141 tgattttacc cccatctggc gaatacttaa tagcattatt taaaatattg tcgacaacct
     1201 gcgtcatctt atctgtatca atttccatcc agatagaatt gatgggataa tctctcacca
     1261 gctcatattt tttctccttt tcctgtcctt tcatcttgtc aaaacgattg aggataaagg
     1321 taataaaagc agtgaagtta atcagttcca catctaggtg actggtagca ttatcaatac
     1381 gtgaaagatg gaggagatcc gtcaccatgc gcatcatacg gttggtctca tcaagagaaa
     1441 ccttgataaa gtctggtgct acagtttcac acaaagcccc ctcatccaag gcttcaagat
     1501 aggattttac gctagtcaga ggagtccgta actcatggct aacattggaa acaaagagtc
     1561 ttcgttcgcg ttcttccttc tcctgctccg tcgtatcatg caaaacagcc accaaacctg
     1621 aaataaagcc agactctcga cgtatcaagg caaagcgaac tcgaaggttc aaatattcgc
     1681 cattgatatc ttgggaatct agcaacaatt ctggactttg ggtaatcaaa tcacgcaatt
     1741 catagttttc ttctatcttg agcaattcca aaatgcttct attcagaaca tcttccttaa
     1801 ccaaccccag ttgcttcttg gctgtatcgt taatcatgat aatctgaccc cgacggttag
     1861 tcgcaagaac cccatctgtc atataaaaca gaatactatt tagcctctta ctctcttgtt
     1921 ctagattttc ctgagtgaga cgaataacct ccgacaagtc attcaaatta ttggtaatat
     1981 tggtgatttc agacccacct tgcatatcaa gaaccttgga ataatctcct gcaatcaaat
     2041 ctttaacctt ttgattgatt tgcttcaact gaatattatc acgtctattt tccagtaata
     2101 agagggtcac aacaaggatg aaacctaaca aaatcaggat aaagataaaa tctctggtaa
     2161 aaatggtttg tttcagtaaa tcaagcatta tttctcatgt aataccctac accacggcgc
     2221 gtcaagatat actctggtcg gctgggcgta tcttcaatct tctcacgcag acgtcgtaca
     2281 gtcacatcaa ctgtgcggac atcaccaaaa tagtcataac cccagacagt ctcaagcaag
     2341 tgttcgcgcg tgatgacttg acctgtatgc gatgctaaat gatacaaaag ctcaaattca
     2401 cgatgggtta agtctagttc ttcgccatat tttttagcca cgtaggcgtc tggaacaatt
     2461 tctaaatccc caatttggat aggttgaggt ttactatctg cttcctgacc atctactggc
     2521 ataggttgag aacgacgcag aagagcttta acacgcgcct gcaactcacg attggagaag
     2581 ggtttcgtta catagtcatc tgccccaagt tccaaaccga taaccttatc aaattcacta
     2641 tctttggctg aaagcataag aatgggcaca ctgcttgtct tacgaatggt cttagcaact
     2701 tctaaaccat caatttctgg aagcatcaaa tccagaataa taatatctgg ttgctctgct
     2761 tcaaattgct ctagcgcttc acgaccatta aaagcagtta caacttcata accttccttg
     2821 gtcatattaa acttgataat atccgagatt ggtttctcat catctacaat tagtattttt
     2881 ttcatatgtt cacctttttc tctactatta taccaaaaaa tagtcagaag acacaatagc
     2941 tagtcttggc tactgtctaa gttggcttgt gcataagcct gccagatttt ttgttggggt
     3001 ttggcaagtg ggtaattctt gaattcttct ggtgaaagcc aacgaacttc cctatctgaa
     3061 aaatcatgga agtcactcac ctgacctgct acaatctgta catgccattt tcgatgacta
     3121 aaaacatgct ggactgtatc aaaacaaaca tcaagccaat caacatctag gtcatagtcc
     3181 tgctggaaac tctcttctgg actggggcca aagttcacac tttcttccgc aacctgatga
     3241 aagaggtcaa actgctcttc ttgcgaaaag ttatcaactt ctataaaggg gaaatgccaa
     3301 aaacctgcca agagcttttc gctttcattt ttttcaagta aaaattgtcc ttgagaattt
     3361 ttcacaacta aggctttaag ataaatagga accggctttt tcttaggaga tttaattgga
     3421 taacggtcca tggttccatt ctgatatgcc gcactaaagt ccttgactgg gctttcttca
     3481 ggtctgggat ttacaggaga ctcaatatca gaccctaagt ccatcaaggc ttgattaaaa
     3541 tcacccggac gatccggatt aatcaagatc tccatcattg cctgaaaaat ttttcgatta
     3601 cttggaatcc caatatcgtg gttgacttca aacagacgcg ccaagacccg catgacatta
     3661 ccatctacag ctggctcagg caagttaaaa gcaatactgg aaatggctcc tgctgtgtaa
     3721 ggtccaatcc ctttcaagct ggaaattcct tcataggtat ttggaaattg gccaccaaag
     3781 tcagtcataa tctgctgggc tgcagcctgc atattgcgaa ctcgagaata atagcccaag
     3841 ccctcccaag ctttcagtaa actctcctca ggcgcagttg ccagactttc gacagttgga
     3901 aaccagtcca ggaatctttc gtagtaaggg ataactgtat ccaccctggt ctgctgaagc
     3961 atgatttcag atacccagat gtgataagga tttttacttc tcctccaagg caaatctctt
     4021 ttgttttcat cataccaagc gagaagtttc tcacggaaag aaatgacttt ctcctccggc
     4081 cacatgacga taccgtattc tttcaaatct aacatatctc tagtataaca cagaaggttt
     4141 cacctgtctt tgtatctgat ttataatatt ttcaatagat agtatataac ttttctatct
     4201 acttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac
     4261 actgttttga ggttgtggat agaactgaca gagtcagtat catataccta cggcaaggtg
     4321 aagctgacgt agtttgaaga gattttcgaa gagtataaat cttattgatg aactgcttgc
     4381 agtctgagaa aaaatgagct tggatattat ttccaaactc acttaaagtc aatttcaatc
     4441 cactagaaca agcctagtac agttccatcg ctttcaacat ccatgttgag agctgctgga
     4501 cgttttggaa gacctggcat ggtcataaca tcaccagtta aggcaacgat gaagcctgca
     4561 cctaattttg gtaccaattc acgaatggta atttcaaagt tttctggtgc tccaagcgca
     4621 tttggattgt ctgagaaact gtattgagtt ttagccatac agattggcaa tttgtcccaa
     4681 ccgttttgaa cgatttgagc aatttgtgtt tgagatttct tctcaaagtt cactttgcta
     4741 ccacgataga tttcagtgac aattttttca atcttttctt ggacagaaag gtcattatcg
     4801 tacaaacgtt tatagttagc tggattttca gcaattgtct taacaactgt ttcggcaagt
     4861 gctactccac cttctgctcc atcagcccag acactagcca attcaactgg tacatcgatt
     4921 gaggcacaga gttcttttaa gactgcaatt tcagcttctg tatcagatac aaattcgtta
     4981 atagctacaa ctgctggaat accgaactta cggatatttt caacgtggcg tttcaagtta
     5041 gcaaaacctg cacgaactgc ctctacattt tcttcagtca gagcgtcttt agccacacca
     5101 ccattcatct taagggcacg aagggttgcg acaataacaa ctgcatctgg agatgttggc
     5161 aagtttggtg tcttgatatc aaggaatttc tcagcaccaa ggtccgcacc aaaaccagct
     5221 tcagtaacag tgtaatcagc caagtgaagg gctgttgtcg tcgccaaaac agagttacag
     5281 ccatgagcga tattggcaaa tggaccaccg tgtacaaagg caggtgtacc gtaaattgtc
     5341 tgaaccaagt ttggcttaat agcatccttc aaaatcaaag ccaaggcacc ctcaacctgc
     5401 aaatcaccta cagaaacagg cgtacggtca tagcgataac caataacgat attcgccaaa
     5461 cgacgtttca agtcctcgat gtccgttgcc aagcaaagaa ttgccatgat ttctgaagca
     5521 actgtaatat caaaaccatc ctcacgtgga ataccgttta gaggaccacc aagaccaaca
     5581 gtcacatggc ggagcgcacg gtcgttcaag tccacaacgc gtttccagag gatacgacgt
     5641 tgatcaattc ccagctcatt cccttggtgc aagtggttgt caatcaaggc agaaagggca
     5701 ttgttggcag ttgtaatagc atgcatatct ccagtaaagt ggaggttgat gtcttccatt
     5761 ggcagaactt gtgcataccc accaccagca gcaccaccct tgatccccat gactggacca
     5821 agagacggtt cgcggatagc aatcatggtt ttcttgccaa tcttgttcaa ggcatccgca
     5881 agaccaatgg taagcgtcga ctttccttca cctgcaggtg ttgggttgat ggcagtaacc
     5941 aagatcaatt taccgactgg attgctctca actgcccgaa ttttatcaaa gctgagttta
     6001 gccttgtact ttccgtacaa ctccaaatcg tcgtaagaaa taccaagttt ctctacaaca
     6061 tcaacaattg gcttcaactc aatactctgt gcgatttcaa tatctgtttt cattcaaaat
     6121 tcctctaacc tcttatatga taattcatta tatcacaaaa caagattttt aacatcttaa
     6181 aactctctaa acgttcgtaa atatctctgt ttttaagact tttagagtcc tttcttaaat
     6241 tttatatggc tttatagttt gaaactatag taaatcttcg tttttaccaa aaatttatca
     6301 ctttcatttt acttaccgct tatttttgtg tacaatagtg ctatgaaaat tttagttaca
     6361 tcgggcggta ccagtgaagc tatcgatagc gtccgctcta tcactaacca ttctacaggt
     6421 cacttgggga aaattatcac agagactttg ctttctgcag ggcatgaagt ttgtttaatt
     6481 acgacaaaac gagctctgaa gccagagcct catcctaacc taagtattcg agaaattacc
     6541 aataccaagg accttctaat agaaatgcaa gaacgtgttc aggattatca ggtcttgatc
     6601 cactcaatgg ctgtttctga ctacactcct gtttatatga cagggcttga ggaagttcag
     6661 gctagctcca atctaaaaga atttttaagc aagcagaatc atcaggccaa gatttcttca
     6721 actgatgagg ttcaggtttt gttccttaaa aagacaccca aaatcatatc cctagtcaag
     6781 gaatggaatc ctactattca tctgattggt ttcaaactgc tggttgatgt taccgaagat
     6841 catctggttg acattgcacg aaaaagtctt atcaagaatc aagcagattt aatcatcgcg
     6901 aatgacctga ctcaaatttc agcaggtcag caccgagcta tatttgttga gaaaaatcag
     6961 cttcaaacag tccagactaa agaagaaatt gcagaactcc tccttgaaaa aattcaagcc
     7021 tatcattctt agaaaggaaa actatggcaa acattctctt ggctgtaacg ggttcaatcg
     7081 cctcttataa gtcggcagat ttagtcagtt ctctaaaaaa acaaggccat caagtcactg
     7141 tcttaatgac tcaggctgct acagagttta tccaaccttt gacactacag gtactctcac
     7201 agaatcctgt ccacttggat gtcatgaaag aaccctatcc tgatcaggtc aatcatatcg
     7261 aacttggaaa aaaagcagat ttatttatcg tggtacctgc aactgctaac actattgcaa
     7321 aactagctca cggatttgcg gacaacatgg taaccagtac agctctagcc ctaccaagtc
     7381 atattcccaa actaatagct cctgctatga atacaaaaat gtatgaccat ccagtaactc
     7441 agaataatct gaaaacatta gaaacctacg gctatcagct gattgctcct aaggaatccc
     7501 tactagcttg tggagaccac ggacgaggag ctttagctga cctcacaatt attttagaaa
     7561 gaataaagga aactatcgat gaaaaaacgc tctaatattg cacccattgc tatctttttt
     7621 gctaccatgc tcgtgataca ctttctgagc tcacttatct ttaacctttt tccatttcca
     7681 atcaaaccga ccattgttca tattcctgtc attattgcca gcattattta tggtccacga
     7741 gttggggtta cacttggatt tttgatggga ttacttagct tgacggttaa cacgattacg
     7801 attctaccga caagctacct cttctctccc ttcgtaccaa acggaaacat ctactcagct
     7861 atcattgcca ttgtcccacg tattttgatt ggtttaactc cttacttagt ctataaactg
     7921 atgaaaaaca agactggtct gattttagct ggggctcttg gttccttgac aaatactatc
     7981 tttgtccttg gaggaatctt cttcctattt ggaaatgttt ataatggaaa tatccaactt
     8041 cttctggcaa ccgttatctc aacaaattca attgctgaat tggtcatttc tgcaattcta
     8101 accctagcca ttgttccacg actacaaacc ttgaaaaaat aaaaacaatc tccgctttca
     8161 aacctgaagg tggagatttt gctctataca gtttcttttt aatgaaatct ttactatagt
     8221 aaaacgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
     8281 ttagaagtag aggtggacta ttctagtttc aatctactat aacttttaac taaaaaatga
     8341 tctataaacc caagtaaatt cttgctttat tgtctggttt attgtaccat actagtgtat
     8401 atgcagttaa aaaggagatt cttgtgaata cacggaaaaa gacacaattt atgacaatga
     8461 cagccctttt aacggctatt gcgattttga ttccaattgt tatgcctttc aagattgtca
     8521 ttccacctgc ttcctatact ttggggagcc acatcgctat ttttatagcc atgttcttgt
     8581 cgcccttgat ggcagttttt gtcatcctag cctctagttt tggatttttg atggctggct
     8641 atcccatggt tatcgttttt cgggcttttt cccatatatc ttttggtgct ttaggagctc
     8701 tttacctaca aaaattcccc gataccctag ataaaccaaa atcttcctgg gttttcaatt
     8761 ttgttttggc tgttgttcat gcccttgctg aagtattagc ctgtgtcctt ttttacgcaa
     8821 cttcgggtac caatgtagaa aatatgttct atgttctatt tgtactagtt ggatttggca
     8881 caattatcca tagtatggta gactatacat tagcactagc tgtctataaa gtgcttcgaa
     8941 aacgccgtta aaaggaaaag ctatgacaaa agatcgcaaa caagccctgc tccaactctt
     9001 gaaagaagct cctaaagccc ttaatggcca aagtttggcg gaacattttc atgtcacacg
     9061 tcaggtcatt gtgcaggaca ttgcaatttt gagagccgat ggcgctccta tcctatccac
     9121 caatcgtggc tacatctata agcaaattga taccaatcct tatgttcaca aacttttcaa
     9181 agtgaaacat gaagttgaag aaatcggtca ggaactcctt gctattgtcg ataatggtgg
     9241 gcatgtccag aataccttga ttgaccatcc cgtttatgga gaaattgaaa ccttgcttaa
     9301 actgtcttgt cgcagagatg tgcaacattt tctagaacaa gtcgagcatt ctgactttag
     9361 acctctatct gaattgacag atggcatcca ttaccaccta gtcgaagccg aaacacaaca
     9421 agacctccac tatatcgagg aggccttgga tcagctaggt tatttagtaa aagactagaa
     9481 gattttcttt tcccaatcgt cttctgtacg gcgaggatag aaaaactctg acttgtcggg
     9541 agcttccatc atttccatca atggtagcat atcataggcc agatttaagt ttggaatctg
     9601 gtctttttgc acccaagaaa cttctccctc ttctgaagat tgaagggtac cagagaactc
     9661 agtcgcctta taacaaatga caatatagcg cccacctgta tctagtggcc aatttttaat
     9721 gccgacaagt tgaggatttt ggatagtcaa ccctgtttct tcgtagattt cacgaatgac
     9781 agactccgca aaagcctcat cattttctac atgacctcca ggaaaggcat aaccagacca
     9841 gcgattgttt tcaggggcgc gatactgcat caccacgcgc tgagtttcga ggtcttcaat
     9901 cagacagata tttgttaaaa ttgttaattg ggaacgggac ataaatttac tcgctttcta
     9961 atttattaaa ttttcagact tactaccaga gatattatct tttacttttt taaaattatt
    10021 tagaatagaa caccattcgt ttttccttta taggctttcc aagttcaagt attttttctt
    10081 gtccatcaaa agtaaaaccc attttttgat agaaagcaat ggcgcgcttg ttatctttca
    10141 atacccataa gaaaatttca gaaaaatgat taagagcagt caaagctgct ttcattaact
    10201 tttgtgcgat accttttcca taatagtctt ttaaaacata taaagcaata atttcaccag
    10261 cttgaatagt ctcatcacga aaattgccat aactgataaa accaaccacc ttcacgccat
    10321 ccatcgcaat caatgtattt tctggatact tttgactaaa gaatcgacat ctttctaatg
    10381 tcattgtatc ctgaaattcc gcaggcaaaa ggtcatcata agactctctc cacgtttgcc
    10441 agtgaacaag ggatttacct tctatctctt taggagtttc cattgatttg ataataaccg
    10501 tcatttattt tctcccagtc ttctctcaaa ataccatatt taatactatc aaaatattta
    10561 ccttgataat aacgaacttt tggaatatga gcttcttttt tcattcttaa tttttcagca
    10621 agtttcatca taccaatatt ccctgaccaa gttgtcaaac ccagatgctc caactccaag
    10681 taatcctgaa acgtcctatc tatccactgc aacatagcaa ctttcccaat accagtgttc
    10741 cagaattttt tatcataaat accaattccc aattccatcc atcttgtttg tttacatacc
    10801 caataacgcg aaacagtccc aactagttta tcatcaacaa aaataccaag gcgatttgag
    10861 ttgcttaaaa tggattctga tttttgtagt tcgaattctt taaaatttga aaaatactga
    10921 taatcatcat aatagggagc atcatactgt ttccaaactg gattaagttg tgaataagcc
    10981 atttcccata aagacatcaa atcttctctc tttaactttc ttaaataaat catactattc
    11041 ccctaatcca aggccttgac ttccaacatc atatcacgga tctgagccgc cagttcaaag
    11101 tcaagcactt cgacggcttc ttgcatttgt ttttctagtt tcttgacgag ttctttgcgc
    11161 tcttgtttgt tgaggctatt gatgtcgact tccttgtcct cttccttagc aactgccttg
    11221 gtcacggcaa tcaggtcacg gatttctttc ttgattgtct gtggtacgat accatgctct
    11281 tcattatagg ccatctgaat tttccgacgg cgggcagttt catcgatagc acgttgcata
    11341 gactgggtaa ccgtgtctgc atacatgatg acatggcctt cactgttacg agcagcacgt
    11401 ccaatagtct ggatgagtcc acgttcgttg cgaaggaaac cttccttgtc agcatcgaga
    11461 atagctacga ggctcacttc aggaacgtca attccttcac ggagcaggtt aattccgacc
    11521 aagacatcaa agacacccaa gcgcaggtca cggataatct ccgtccgttc caaggtcttg
    11581 atatccgagt gcatgtactt gaccttgata cccatttcct tgaagtagtc ggtcaaatcc
    11641 tctgccattt tcttggtcaa agttgtgata aaggtacgct catttttttc aacgcgggca
    11701 ttgatttcac ccaagaggtc atcaatctgt cccatagtcg gacggacttc cacctctgga
    11761 tccaagagtc ccgttggacg aatgatttgc tcaatcactg tctcggtctg ttcattttca
    11821 tagtcaccag gtgtcgctga aacgtaaaca atctgatgaa cgtgactctc aaactcctcc
    11881 cgacggagag gacgattgtc caaagcagac ggcaaacgga aaccataatt aaccagcatt
    11941 tctttacgcg aacggtctcc attgtacatg cccttgattt gccctatggt catatgactc
    12001 tcgtcaatca taatcaagaa atcatctggg aagaagtcga gaagcgtata aggaggctct
    12061 ccttcgctcc gtccatccat gtggcgagaa taattttcaa ccccattggt atagcccatc
    12121 tcacgcaaca tttcgatatc atactctgtc cgctgtttca aacgctgggc ttcaagcagt
    12181 ttaccttcct tttcaaagac agctaattgt tcttccaact cggcctgaat ctttgcaatg
    12241 gcaacttcca tgtggtcgtc attggtcaca aagtgtgtcg ctgggaaaat cgctaaatga
    12301 tccacttctc ccaacacctg acctgtcaga gcctcaactt cacgaatacg gtcaatttcg
    12361 tctccaaaaa attctactcg aaaggcatgt tcatctcggg aagctgggaa aatctctacc
    12421 acatccccac gaacgcgaaa tcttccgcgt tggaaatcaa tatcattacg ttcaaactga
    12481 atatcgacca agtcattcaa gagtttatca cgagaaatct ctagaccagg acggagacta
    12541 acgacactat cagcgtattc cttgggcgaa cccaaaccat agatacaaga gactgaggcc
    12601 acgacaataa catcattacg ctccaaaagg gctgaggtag ctgagtggcg aagcttgtca
    12661 atctcgtcat tgacagaact atccttctca atataggtat cgctagaagg gacataggcc
    12721 tctggctggt aataatcata gtaggatacg aaatactcaa ctgcattttc agggaaaaat
    12781 tccttaaact ccccatagag ctgaccagcc agagttttat tgtgggcaat aaccagagtt
    12841 ggtttattga ctttagaaat gacctgactc atagtatagg tcttccctgt tccagtcgcc
    12901 cccatcagaa tctgagcttt ttctcccccc tcaatgttat ccaccaactg ctcgatagct
    12961 tggggttgat ctcctgatgg ttgatatttt gatactagtt taaattgatt atctgtaatg
    13021 tgattgatca taagaatcct ctctccatgt gctattccta ttttagcata cttatagtat
    13081 tttcacgaag aaaaggacgg accgaagtca catcctttca ttttctttct ttaatttatt
    13141 agcaagatag acaatcagca gtagtaatac cagacttgtc ataatggaac cttctatgcc
    13201 aaaagaacca cctgatagcc aatcttgatt gccttgtggt aaaaaggtca tcagagacgt
    13261 tcctgacggt tgaccactaa ctaaaatccc aaagagatta ccctgagcaa aattccaagc
    13321 accatgaata cctgcaacac cccaaactgt atcagttttg agaaggtaaa gagccatggc
    13381 aactccgaat aaaaagagat ttactagaga tagaggggtg agaccagaat tgcccatatg
    13441 aagcagggta aagaacaggc tagatataag aatagctagt tttagattgg ttcttgaggc
    13501 caattgagga agtagccaag cacgggccac cacttcttct gctgtcccct gtaaaatcca
    13561 aaatgggata gtaaagacga caaaggcaag agaataagga ttcaagtgaa tggattccaa
    13621 acgatattga cctaagacca ctaaacctaa caaggtcaga agaaaaagtg ccaggcctag
    13681 actaaatcct ttcagaagat tgctgaggaa attctctcta taaaatccca aggttcgaat
    13741 aggtcttttc tcaacttttc ttgtccatct gaacacagtg ttaagaataa aaccaaaggc
    13801 cagtaatcct aaaattaaac gaaagtcact tgttttatcc gtcaagctct gatgcaaggt
    13861 ctgcaagtag cttgcaagat tttgaccagc ctctccaaaa tttctagcaa gtccgatgag
    13921 agctaacaag ccaataccat acaaagtaaa agccacaaac tctcctatga agacaaaaac
    13981 aaaggctaac aaggggcttg tgtaaatgtt taaactcatt tttgaagctt ggaagtcttt
    14041 aaatattctt ttgttcttca tatccccgtc ctctttt
//
LOCUS       DAVKUR010000049        13900 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKUR010000049 DAVKUR010000000
VERSION     DAVKUR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.049"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..513
                     /locus_tag="VW749_001671"
     CDS             1..513
                     /locus_tag="VW749_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0175681.1"
                     /translation="MIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSDHEWM
                     LTDIKNFLTKHKAWVIDGNYSWCCYQERMQEADQIIFLNFSPLTCLFRTFKRYLKYRG
                     KVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRELDQF
                     LDKKRKSYNS"
     gene            complement(536..1246)
                     /gene="deoD"
                     /locus_tag="VW749_001672"
     CDS             complement(536..1246)
                     /gene="deoD"
                     /locus_tag="VW749_001672"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0175682.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1904..2416)
                     /locus_tag="VW749_001673"
     CDS             complement(1904..2416)
                     /locus_tag="VW749_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0175683.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(2441..3421)
                     /locus_tag="VW749_001674"
                     /pseudo
     CDS             complement(2441..3421)
                     /locus_tag="VW749_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(3897..4706)
                     /locus_tag="VW749_001675"
     CDS             complement(3897..4706)
                     /locus_tag="VW749_001675"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0175684.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(4706..5263)
                     /locus_tag="VW749_001676"
                     /pseudo
     CDS             complement(4706..5263)
                     /locus_tag="VW749_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(5265..6476)
                     /locus_tag="VW749_001677"
     CDS             complement(5265..6476)
                     /locus_tag="VW749_001677"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0175685.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(6490..7173)
                     /gene="rpiA"
                     /locus_tag="VW749_001678"
     CDS             complement(6490..7173)
                     /gene="rpiA"
                     /locus_tag="VW749_001678"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0175686.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(7455..8327)
                     /locus_tag="VW749_001679"
     CDS             complement(7455..8327)
                     /locus_tag="VW749_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0175687.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(8469..9326)
                     /locus_tag="VW749_001680"
     CDS             complement(8469..9326)
                     /locus_tag="VW749_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0175688.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(9480..10214)
                     /locus_tag="VW749_001681"
     CDS             complement(9480..10214)
                     /locus_tag="VW749_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0175689.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(10214..10897)
                     /locus_tag="VW749_001682"
     CDS             complement(10214..10897)
                     /locus_tag="VW749_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0175690.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            11087..11317
                     /locus_tag="VW749_001683"
     CDS             11087..11317
                     /locus_tag="VW749_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0175691.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            11546..13804
                     /locus_tag="VW749_001684"
     CDS             11546..13804
                     /locus_tag="VW749_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0175692.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT         4123 a         3137 c         2541 g         4099 t
ORIGIN      
        1 attatcggat attctggttc tggtaagtca actctagcag aaaagttatc taactactac
       61 tccattccaa aactgcacat ggacacactc caatttcaac ctggttggca agacagtgac
      121 cacgaatgga tgttaaccga tataaaaaac tttctcacca agcataaagc ttgggtcatc
      181 gatggtaatt attcttggtg ctgctaccaa gaacgaatgc aagaagctga ccaaatcatc
      241 tttctcaatt tttcgccatt gacctgtctc tttagaacct ttaagcgtta tcttaaatac
      301 cgtggaaaag tcagagaaag tatggcggca gattgccctg aacgctttga ctgggagttt
      361 atcagatgga ttctttggga tgggcgtagc aaaactcaaa aagaaaatta ccaaaaactt
      421 tgccaagaat attcacataa agtcactatt cttcgaaatc agagagagct agatcaattt
      481 ctggataaga aaaggaagtc ctacaattca taaagggctt cctttttggc tataattatt
      541 ctgcaatcaa ggtttccaaa ccaaccttca tcatatcagt gaaggtattt tgacgttctt
      601 ctgcagttgt gtcttcgtct ggattgacca agctatcaga gatggtcatg atagctagcg
      661 catcaacatg gtattgggca gcaagatagt aaagagctgc tgcttccatt tccacagcct
      721 tgactcccca tttaccaagc tcgatattct tttcaaagta atttgagtaa aagacatcag
      781 atgacaaaac gttcccaacg tgagtagtca taccaagttt tttggcgata tggtaggctt
      841 tatcaagcaa atcaaagcta gcaatttgtg gaaaatcgta ctgtggccag tcattacgaa
      901 cgatgtttga gttggttgca gccgcctgcg ccaaaactaa ttcacgaaca tgaacctctt
      961 cattcaaaga acctgcagtt cccacacgaa tcaatttctt cacaccgtag tctacgatta
     1021 actcacgcgc ataaatcgaa atagatggca ttcccatccc agttcccatg acagatacac
     1081 agtgaccctt gtaagtacca gtgtaaccaa acatgttacg cacttcgtta aaacaaacag
     1141 catcatcaag gaaattctcc gcaataaact tagcacgaag aggatcccca ggaagaagaa
     1201 ttttatcagc aatttcaccc tgctgagcag caatatggat agacataatt tatgatacaa
     1261 agagcgagaa gaaaacgact gaaaattagg aacctgacga gaaatcctga tttttcagtc
     1321 agattatcta ttttccgagt tttccgctcg tgttcaaatc aaaacacacg ctctaccttt
     1381 ctttatttta tattttatat tgagaaagat accaaaccca tcaaaaagcg aagggaaaat
     1441 aggagttggg cgcagtgagc gatgctcgct agaccaacta tctttttccc actgctttta
     1501 gggtggggtc aattcctttc tttcttaatt ttgatttaga ggagagtcgc ccgtattcag
     1561 ttcagcgaat acagtttacc catcctttcg tttttatttt tagaaaagtt ttctactcgt
     1621 gttcaaatta gaacacgcgc tctacctttc tgtttatact cttcgaaaat ctcttcaaac
     1681 cacgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta tctacaacct
     1741 caaagcagtg ctttgagcaa cctgcggcta gtttcttagt ttgctctttg attttcattg
     1801 agtattaatt ttgttctttc acagagagct acctgagttc tattcaagct caggtagtac
     1861 tttcttataa actagacaaa ctaactgtca ttgtaccatc agattacaag acatcatcgt
     1921 cactcacctt ggaattcaat gtcgtacccc aatgggtaat tttacggtgg ggttgagcta
     1981 aaattggtct gttttcatag attgtttgcc atctattcca tagtaggccc gtctttttct
     2041 caatcttaac tcgcagattt ctcatatttt ctttgattgg gaggttgagg acaaaacctg
     2101 cagtctggtt gcgaccgttt ccttcccaag aatgactacg aacaacttgg tttccatctt
     2161 tatctactgt aacttcttcc caagttatgg agtagcgggc aatgtaagct ccactgtgtt
     2221 gaattgtcaa tgttttatct ttcacaggag tctgactgat tggttgaact ggcttagaaa
     2281 cttgtgtcgc cgtttcagca ttcgtagcta taaagcggaa aacttcaact tctgcaagac
     2341 tgagggcatt atagccttct agcccaatcc gaacatagcg cgctttttta tggttaatcg
     2401 taatttgtgc tgacacatct ttaggagata ttatacgttt tcactcaatt tctttaccag
     2461 aactgtctaa aagaatgaca tcaaagtttg ccaatctatc ctgggcagtg tctgttcggt
     2521 tgtaaatatt gatttggcga atggtttctt ctttagccaa atctacttgc caccaaggct
     2581 tagattggaa gtttgtatga gtgacagaat tgtgaccata gttaccatcg actttgccat
     2641 ccacagctct tctagcatct cctccgaaag ctgtcgaact ttgagtaacc tgttttccta
     2701 aggcaatatt ttccattggt tcagcgcttg gttgactaga agattgaggt agagcctgtt
     2761 tcttaaagaa tcgcacttta tccaatttcg gatcacgata accatgttta tccaaggtag
     2821 cttgtttacc aatattaaag ttaggaatat cattcattgg actttcaaaa tagccacgag
     2881 aacggtgttt aaagcgtgaa ttacctgtaa atgtaacaat atcacgatta ttatgaatca
     2941 agggagtcac aacattgtca ttatcaacca cataatgctt aatttttcca ctaacagcta
     3001 atttacgact ttccaaacca acatctcaga aaccattctt agcatcccaa acagttctgg
     3061 aagtaatcac tttaggagca ctgaaagttg tcactttcct caatacatgg ttataaaaat
     3121 caggatattt ttggtaagct tcaaccgctg caatctgagc taggtaacat ccaagagaat
     3181 gacctgtcat atacaactta gtaatactta tatccttggc taattcccca acaaccttgc
     3241 ggatatcatc cgcttgagct ggctctatta tctctacttt tgactcttcc cttttgtttt
     3301 caagaacttc acttgcttcc ggaagcgttt gaggagctag tcttggctcc tctctaagag
     3361 gagtttctag ttttggagca tcattttctg actctttcaa ttcctcctta gaatctagca
     3421 cacctattac cacttcagat gttacatctt gctttacttc attggctgaa attccagctg
     3481 gagctagaaa tcaaagccga ctacaacaga tacaactccg atacttaatt ttttatgcca
     3541 aagcgcataa ttcgttgacc aattttcatt atttcttatc tttcttttcg tttatttaca
     3601 agcagactca agcgaaatct cattgtgcta tatatgataa gactgagaaa ttcagaaagt
     3661 caattcattc tcatctctcc ttatcatact agtctacttg gctaggaagc taatgctagt
     3721 atcctagaat cttgtctttc acaatgctgg ctatcagatc agacacacct attcttccgc
     3781 ttctttcagt tataagagca ggaagaagct catagtattc ctctgtttct tctttaatcc
     3841 ggataggcag tcaatcctga aaaaacagag gcactccccc ttttaaatct tttttcttac
     3901 aattcagcaa gaatcgcttt aagcaagcct ttgaaatcac ctttaacacg ttcagtcact
     3961 tctacaactt cttcgtgatt gagttcttct tggaaaccgg ccgcaaagtt agtgatacat
     4021 gaaattccca gaactttcaa gccagagtgg gccgccacga taacttcagg aaccgtagac
     4081 ataccaactg catctgctcc cagtgtctta taggaacgaa tttctgctgg tgtttcataa
     4141 gtcggaccag taactccgat atagacacct tcatcaagct tgatattaag ttttttagcc
     4201 acttcatggg cagtggcacg gtattctggt gtgtaggccc tagacatatc tgggaaacgt
     4261 gggccaaagt catccaagtt ttcacccatc aatggatttt gccccgtcat gttgatatgg
     4321 tctgagatag ccatcaaggt accaggacca aatccgatac cgccagctgc attggttaca
     4381 ataacacctt cacatccaag aactttcatc acacgaactg ggaaagtcac cacttccaga
     4441 ggattccctt catagaaatg gaaacgccct tgaagagcca agaccttgcg acctgccagt
     4501 tcaccatata ccaatttacc agcatgaccg actactgttg aacggcccca gtttggaatc
     4561 tcagcatagt ctactacaac tggattttcg atttcttctg ccaattctcc aagtcctgac
     4621 ccaaggatta gaccgaactc aggggctgca attccctttt ctttcaggaa agtagcagtt
     4681 tcatggattt tgtttaaaaa tgtcattatg tgtctccttt attatttttt agcatttgac
     4741 caattttgtc aaaggtttta gcattacgaa tagtaatgtg gcggtagaaa ggcaccttca
     4801 gcaagtactt atgataggca gtcttagaat aggattcttc agaaaatttc ccccagaaaa
     4861 tcccaagttt tctaaaataa agcacttcat ctttcagctc taaactttca actgtcgcga
     4921 tgacttggtc cacatccaaa ccctcagtgt aaaagagaaa atcttttcgt gccaagtctc
     4981 tgctccacca agctggtaga ttttcaagtt ccgcctcaaa gtcctctaga ctcagtaaag
     5041 aaaagctctg aataaatgga taatggactg caaagaaagt ctctagcttt taaaccaatt
     5101 gggctttgga atctatcgaa gtaaagaaaa tattgccact gttgatgtag ctctcaacct
     5161 tttccagtcc caagtttgtc aattcttgac gaagctccgc cataacgacc ttattcttac
     5221 taccaacatt gatacctctc accagcaaag catagcgcgt catcttatac caatttatct
     5281 aagaaacttt ccccaatcat agcagtttcc acaccaaagt tatcggcaac agtcgctgaa
     5341 atatctgcaa aatgtcctac tggaatgaga ccatttcctt taaaggcagg gctatatgcc
     5401 aacaatggaa tatattcccg agtgtgatcc gtccctgcat acgttgggtc atttccatgg
     5461 tccgcagtaa tcaagagaag gtcattctct ctcatagctg cgataatttc aggtaagcgt
     5521 tcatcaaact catgcaaaca atcacggtaa ccgtgagcat tacgacgatg gccgtaaagg
     5581 gcatcaaagt caactaggtt tgtgaatgag aatccttttt caaactcagc aagtcccata
     5641 gtcttcaata gtgtatcaat tccatgacta tttgacttgt tgtgacccat gtcatggttg
     5701 ataccagcac cgttaaagat atcgttgatt ttacccacag cataagtatc gataccagcc
     5761 tcattcaatt tatccaaaac agttggggaa aatggagata cagccaagtc acgacggttt
     5821 gccgtacgag tgaagttacc tggttcacct acataagggc gagcaatgat gcgaccaaga
     5881 agggcaggac gctcaagggt aatcgaacga gcgtattcac agatacggta caattcatcc
     5941 aaaggaataa tgtcttcgtg ggcagcaatc tgcaaaacag ggtcagctga agtatagata
     6001 atcaactctc cagtttccat ctgacgtggt ccaaaatcat cgataacagc cgttcctgaa
     6061 taaggtttgt tggcttcacg aataaccttg cgtcctgaga attcttcgat ttttgtcagg
     6121 atttcttctg ggaatccgtt ccagaaagta tcgaaaggct cagtaatgtt gagtcccatg
     6181 atttcccagt gtccagtcat agtatcctta ccaagagata cttcctctaa ttttgttgca
     6241 tatccagttg gattgatttc agctgctaca gtcttaagag gagtttcacg aggaatattt
     6301 ccaagaccta ttttagccat gtttgggaca ttcaaaccaa ctgtttttga aatgtgtccc
     6361 agtgtgtcag aagctccatc tggaacccct gcattgacaa agttattagc atctggtgct
     6421 gcaccgattc ctacagaatc cagtaccacc aaatgaatac gattaaattt agacatctta
     6481 tgcccccttc tattttcctt tttttgaagt tgaaatctga actccatctc gtccagcaac
     6541 gattacctta tccaccattt ggttgaataa accatgctcc acaacaccaa cgacatggtc
     6601 caattcttgt ccaaaagcaa ttggattttc aatgacatcc aaggcgaggt caatgataaa
     6661 attctgcata tccgtcacaa aacgttggcc gtctttttca cggaaacttg gtttgtagcc
     6721 agctcgttca aaatgacgaa agacctgctc tgcaccatac tgaaccactt ctactggcaa
     6781 tttaaaagca cctagttttt cgaccagctt gctttcatcc accacccaaa tgtattcttt
     6841 tgatggtgtt gcgaccacct tttccatgag aagggcacca ccaccgcctt tgattccatt
     6901 aaactgacta tccacttcat ccgcgccatc aaccgtcaca tcgacaaagt ctacttggtc
     6961 aatagacttg agcgggatat taaggccttc tgcctgttta gtggtcacac tagaagttgt
     7021 tacagctgta atctgcaatc cttcttcctt gatacgacga ccgatttctt cgacaaaata
     7081 ataggcagtc gagcctgttc caagtccaac gaccattcca tcgctcacga actcagcagc
     7141 cttgatacct gccattttct tcagattttc caccgattta cctccatcat tctcagttct
     7201 tattttacta tgaaaccgct ttttattcaa gtaaaaacat caaatctaca tttttcatca
     7261 atctttcttt aaaaatatgc attttatttt taccaaacga ataaaaatga gtttatcttt
     7321 tatgtatttg atttgttcat ctctttccag ttacaaaaac aaactcttaa ctttgatacg
     7381 tctagtttag ccttaaagca ggcgcatttc aagaatcata aattaagaga aggaagtaga
     7441 tttatctgtc tattttaaac aagtttatct ttgcttaccc tctcttgttg acaaataatt
     7501 ttcattattt tgggaagata cctgctgatt tccgtcggta agaccacata attttcctga
     7561 gatagttctt gggctatggc tgaatgaaga tgggtcgcta ctgccacacg ctcgtagaga
     7621 ctggcctgtc ggaattggcc tacaaatcct gcgatcatcc cagccagagt atctcccatt
     7681 cccccagtcg cctgataagg accaccaacc tgtaactggt aataatcaga ttggccaact
     7741 tcccaaatac gagtagctgg gcctttctcc accaaaattg ttccttgagg gaaggaagtc
     7801 agaacactag ccgttgcatc ttccttttgc ttttcaatcg taattccaga taatttttcc
     7861 cattcttttt ggtgaggagt taggataagc tggcttgagg gaaatgacaa acttgtccta
     7921 gcaagaatgg tcaaggcacc tccgtctaca atcaaaatct gattttggct taaattaaca
     7981 aagacctgtt ttactagatt ttctccagaa gcatcgtctc gtaaaccagg ccccaacaag
     8041 acaacttctg ccttctccaa ttgctctttt aacaattgct ggtcttgaag agaaaaggcc
     8101 ataggctcag gtaaatggct gtgcagagcc gggatatttt ccctgtccgt tccaacggtc
     8161 accaatcctg caccgctttt tacagctgct aaagcagcca tgatgatggc acctccataa
     8221 ggataagtac caccaagcag cagcagacga ccataatctc ctttatgact tgaacgagaa
     8281 cgttcaataa taactttttc taataaggtt tgattaatca ctttcatcct tttttcctct
     8341 cacttttatt atacaataaa aaggagacgc agacctcctt ttgtaatctt atatctaaaa
     8401 tttaatattc atttctgcca ttttagatat agctatagaa aatacactct attaatcgaa
     8461 tgtttctctt attttctatc caatgtccga agtgctgctt gataagtttg ctccatcagc
     8521 atggtaatgg tcataggacc gacacctcca gggactggcg tgatatagct agcaagtggt
     8581 gcaactgcct cataatcaac atctccacag agcttcccat tttcatctcg gttcatccca
     8641 acgtcaatga caaccgcacc tggtttgaca aagtcagcag tcacaaactt ggcgcggccg
     8701 attgcgacta caagaatatc tgctttagca gccaccttgg caagattatg agttcgtgag
     8761 tgggtcaagg ttactgtcgc atttttagcc aaaagaagct gagccatagg ttttccaacg
     8821 atatttgaac gaccgatgac gaccgcattt ttaccttcca agtcaatccc atattcatga
     8881 aacatttcca taattcctgc aggtgtcgag ggaatcatga ctggatgtcc agaccaaaga
     8941 cgtcccatgt ttaagggatg gaaaccatcc acatcctttt ctgggtcaat ggctaataaa
     9001 accgcctctt catcgatatg ttttggtaat ggcaactgga ccaaaatccc atgccaagct
     9061 ggatcctgat tatatttagc aatcaggtct aacaattcct cttgagtaat ggtctctgga
     9121 actcgcacta cttcgctacg ggaaccagcc gcaagagctg acctctcctt gttgcgaacg
     9181 tagacttggc tggctggatt atccccaacc aaaatcacta ccaaaccagg cactagagct
     9241 gtttcttcct ttaattttgc agtcttttca gccaactgcc cctgcaattt ggccgctaaa
     9301 gctttcccat caataatctg tgtcatatca cttctctttt ctttcaaata tcttccatta
     9361 taccaaaaac tgctagtgcc ctctaacact tctttcctag gttatcctat agtttcaaac
     9421 tataagaaaa agctctggtt gaacttttca ctaatcttgt cttgaaattt taaaatagat
     9481 tataaaacct tactcaagaa atctttagtc cgttgttctt gggtttgttc aaaaatctgc
     9541 tcaggtgtcc catcttcaac aaccacaccg tctgccataa agataacacg atctgccacc
     9601 tcacgggcaa atcccatctc atgtgttacg ataaccatag tcatccctga cttggcaagg
     9661 tcttgcataa cagccaatac ctcacctacc atttcaggat ccaaggctga agttggttcg
     9721 tcaaagagca aaacatctgg ttccatagcc aacccacgcg cgatggcaat ccgttgttgt
     9781 tgcccacccg acagactctg tggataagcg tctgccttat ctggcaaacc aactttttcc
     9841 aaaagctctt gggctctctt ctcagcaact ttcctgcttt cacctttagt cttgataggt
     9901 gacaaggtaa tattttccat cacagtcata ttaggaaaga ggttaaattg ttggaaaacc
     9961 atgcccatct tctcacgcat ggcaaacagg tcattcttct tgtccgtaat atcgactccc
    10021 tcaaagataa ccttcccctt ggttgcttcc tccaacaaat tcatagagcg aagcaaggta
    10081 gatttcccac tccctgaagg accgatgata acgacaactt ctcctctttt aatctcgagg
    10141 ttgatgccct tcaatacttc attctttcca aaagatttat gtaaattttc aatttttatc
    10201 aaggtttctg tcattatttc ttatctcctt gtcccatatg tttttcaaaa gctttcaagg
    10261 ctactgtcag aatagaggtc ataatcaagt agtaaaatgc tgcaaataaa agtggtgtta
    10321 aaggtagata ggttgttgta gaaactgttg tagccccatt ccacaactcc atgaccccaa
    10381 tagctgataa gagggagctg tccttgataa tggtgataaa ttcgttcccc aatgctggca
    10441 agatattttt gactgcttgt ggcaaaatca cataacgcat cgcattttta ggacgaatcc
    10501 ctagcgaata agccgcctct agctgacctt ttggaaccgc attgattccg gcacgaacag
    10561 tctccgaaac ataagcacca ctattcatag agataatcaa aatccctgga atcagacgcg
    10621 aaaaatcaac acctaaaatt ccaatctgaa tagtcggagc attgatatgc ataagagcaa
    10681 aggcaatcat aatttgaacc atcatcggtg tcccacggaa aatccaaacg tacaagttgg
    10741 ccaaccaaac aagcggttta aactttgaac gttgcccaaa agccaagaca acacccaaaa
    10801 tagttcccaa aaagataaca cagatagaaa taagaatcgt cacaacagcc ccatagttaa
    10861 aataaggtaa atacttaggt aaaaaagaaa aattcatagt cacactgctt tctaaaatag
    10921 aatactgtat gattataaca tgttttgaat taaaatttaa attttttatc caatttattt
    10981 aaaaatcttt aaactagcag aattaacgag aaatcttagt tttttctagt caagttggcc
    11041 tcctttatgg taaaatagta acgataagaa atgaaggaga atcaaaatgg aatcacattt
    11101 ggttagaatc atcaaccgcc ttgaagcaat ggcaaacgat ggcggaaatt taaaacgtaa
    11161 ttttgaacgc gaaggagttg ttgttgcaga agttgcgtac agccacgacg aagaaaacgg
    11221 cccaatcttt acccttcgtg acgtagaaga tcgcgaaacg tatacgtttg atagcattga
    11281 cttaatcgca atggaaattt acgaacttct ctactaatct aaaacaagct gggattgtcc
    11341 ctgcatgtct aagtaaaatc ctttttgtct cacaaatagg atttttttat agtccaaatt
    11401 cacaaaaatt ttcattgtaa caacttctca aagcttcaat ctttttactt gctttacacc
    11461 ccaatcctgt tataatgaga gtatagaatt tgactatttt tgacctttaa acaagtcagg
    11521 ctaaagaaag aaatgaggta gatgtatgct ttgtcaaaac tgtaaaatta acgactcaac
    11581 aattcatctt tacaccaatc tcaatggaaa acaaaaacaa attgacctct gtcaaaactg
    11641 ctataagatt atcaaaacag atcctaacaa tagcctcttc aaaggtatga cggatctgaa
    11701 caatcgtgac ttcgatccct ttggtgattt cttcaatgat ctaaacaatt tcagaccttc
    11761 tagcaatact cctcctattc ccccaaccca atcaggtgga ggttacggtg gaaacggcgg
    11821 ttatggttcc caaaatcgtg gatctgctca aactccgcca cctagccaag aaaaaggcct
    11881 gctggaagaa tttggtatta atgtaactga aattgcccgt cgtggagaca ttgaccccgt
    11941 tattgggcgc gacgatgaga ttatccgtgt catcgagatt ctcaatcgta gaaccaagaa
    12001 taatcctgtc cttatcggtg aacctggtgt cggaaaaacg gccgttgtcg aaggtctagc
    12061 tcagaaaatt gtcgatggcg atgtgccaca taaactccaa ggtaaacaag tcatccgtct
    12121 ggatgtggtt agcttagttc aaggaacggg gattcgagga caatttgaag aacgcatgca
    12181 aaaactcatg gaagaaattc gcaaacgtga agacatcatc ctctttatcg atgaaatcca
    12241 tgaaattgtt ggtgctggtt ctgcgagtga tggtaatatg gacgcaggaa atatcctcaa
    12301 gccagccctt gctcgtggag aactgcaact agtcggtgct actaccctca atgaataccg
    12361 tatcattgaa aaggatgctg ccctcgagcg tcgtatgcag cctgttaaag tcgatgaacc
    12421 aacggtggat gaaacaatca ctattctcaa agggattcaa aagaaatacg aagattacca
    12481 ccacgttcaa tataccgatg ctgcgattga agcagctgca actctttcca atcgctacat
    12541 ccaagatcgc ttcttgcctg acaaggccat tgacctccta gatgaagctg gttctaagat
    12601 gaacttgacc ttgaattttg tggatcctaa agtaattgat cagcgcttga ttgaggctga
    12661 aaatctcaag tctcaagcta cacgagaaga agattttgag aaggcggcct acttccgcga
    12721 ccagattgcc aagtataagg aaatgcaaaa gaaaaagatc acagaccagg atactcctat
    12781 catcagcgag aaaactattg agcacattat cgagcagaaa accaatatcc ctgttggtga
    12841 tttgaaagag aaagaacaat ctcaactcat ccatctagcc gaagatctca agtctcatgt
    12901 tattggccaa gatgatgcag tcgataagat tgccaaggct attcgccgta atcgtgtcgg
    12961 acttggtacc cctaaccgcc caatcggaag cttcctcttc gttgggccaa ctggtgtcgg
    13021 caagacagaa ctttccaaac aactggctat cgaacttttt ggttctgctg atagtatgat
    13081 tcgctttgat atgagtgaat acatggaaaa acatagtgtg gctaagttgg tcggcgctcc
    13141 tccaggttat gttggctatg atgaggctgg tcaattaact gaaaaagttc gccacaatcc
    13201 atattctctc atccttctcg atgaagtgga aaaagctcac ccagatgtta tgcacatgtt
    13261 tcttcaagtc ttggacgatg gtcgtttgac agacgggcaa ggacgcaccg ttagcttcaa
    13321 ggatgctatc attatcatga cctcaaatgc aggtacagga aagaccgaag ctagcgttgg
    13381 atttggtgct gctagagaag gacgtaccaa ttctgtcctc ggtgaactcg gtaacttctt
    13441 tagcccagag tttatgaacc gttttgatgg cattatcgaa tttaaggctc tcagcaagga
    13501 taacctcctt cagattgtcg agctcatgct agcagatgtt aacaagcgcc tctctagcaa
    13561 caacattcgt ttggatgtaa ctgataaggt caaggaaaag ttggttgacc taggttatga
    13621 tccaaaaatg ggagcacgcc cacttcgtcg gactattcaa gactatattg aggacacaat
    13681 cactgactac taccttgaaa atccaagcga aaaagatctc aaagcagtta tgactagcaa
    13741 gggaaacatt cagattaaat ctgccaaaaa aactgaagtt aaaagttctg aaaaagaaaa
    13801 ataaatccta taaaaaaaga gtagaaaatg aaatttttct gcttcttttt ttactaaaat
    13861 aactgtaatt tcttgacagc ttgccctttg tccattatga
//
LOCUS       DAVKUR010000050        13569 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKUR010000050 DAVKUR010000000
VERSION     DAVKUR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.050"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(117..1253)
                     /gene="lctO"
                     /locus_tag="VW749_001685"
     CDS             complement(117..1253)
                     /gene="lctO"
                     /locus_tag="VW749_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0175693.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(1878..3368)
                     /gene="lysS"
                     /locus_tag="VW749_001686"
     CDS             complement(1878..3368)
                     /gene="lysS"
                     /locus_tag="VW749_001686"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0175694.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(3496..3642)
                     /locus_tag="VW749_001687"
     CDS             complement(3496..3642)
                     /locus_tag="VW749_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0175695.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            3675..4592
                     /locus_tag="VW749_001688"
     CDS             3675..4592
                     /locus_tag="VW749_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0175696.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFG
                     LARNFNINISGETSVIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTTSFW
                     IYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            4593..5351
                     /locus_tag="VW749_001689"
                     /pseudo
     CDS             4593..5351
                     /locus_tag="VW749_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            5363..6223
                     /locus_tag="VW749_001690"
     CDS             5363..6223
                     /locus_tag="VW749_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0175697.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(6303..6950)
                     /locus_tag="VW749_001691"
     CDS             complement(6303..6950)
                     /locus_tag="VW749_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175698.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKPGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(6947..7645)
                     /locus_tag="VW749_001692"
     CDS             complement(6947..7645)
                     /locus_tag="VW749_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175699.1"
                     /translation="MGKLSSYMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(7655..8407)
                     /locus_tag="VW749_001693"
     CDS             complement(7655..8407)
                     /locus_tag="VW749_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175700.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(8407..9171)
                     /locus_tag="VW749_001694"
     CDS             complement(8407..9171)
                     /locus_tag="VW749_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175701.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(9267..9672)
                     /locus_tag="VW749_001695"
                     /pseudo
     CDS             complement(9267..9672)
                     /locus_tag="VW749_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9852..10484)
                     /locus_tag="VW749_001696"
     CDS             complement(9852..10484)
                     /locus_tag="VW749_001696"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0175702.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            complement(10518..11219)
                     /gene="pyrF"
                     /locus_tag="VW749_001697"
     CDS             complement(10518..11219)
                     /gene="pyrF"
                     /locus_tag="VW749_001697"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0175703.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            11540..11632
                     /locus_tag="VW749_001698"
                     /pseudo
     CDS             11540..11632
                     /locus_tag="VW749_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11954..12667)
                     /locus_tag="VW749_001699"
     CDS             complement(11954..12667)
                     /locus_tag="VW749_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175704.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(12660..13493)
                     /locus_tag="VW749_001700"
     CDS             complement(12660..13493)
                     /locus_tag="VW749_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175705.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
BASE COUNT         4334 a         2823 c         2341 g         4071 t
ORIGIN      
        1 actgtcctga ttaatttgtc ctattcttat ttcattttat tatagttttc gatagcgatt
       61 tattcttcca atacacgaag aaaaacctcc acattcagtg gaggcaatct gttttatcaa
      121 tacaatttta agtcacgagg gtcaactggg aaggttgggt tgtatggatt gtgacggagc
      181 ttaaagtgtt tgacatcttc aatggtctga gctccagaca attgcataac tgtcttcaat
      241 tccgcattca agtgttcaaa gacttgacgc acaccgacac taccaccgag agccaagcca
      301 taaataacag ggcgaccaat agctaccaag tctgctcctg aagccaaggc tttaaagacg
      361 tgttgaccac gacgaacacc agagtcaaag acaatcggca cacgtctatc aactgcttct
      421 gccacttctt gaagcgagtc aaaggcagct ggtccaccgt cgatttgacg accaccgtgg
      481 ttggttaccc agataccaga agctcctgca gcaagtgaac gttcaacgtc ctcacggcat
      541 tgtggtccct tgacatacac aggaagacca gagtattcag cgataaattc tacatcgcgt
      601 ggagacaagc gttgtttagc tgatttgtaa acaaagtcca ttgatttacc agcaccttct
      661 ggcaggtatt cttcaacaat cggcatgcca actgggaaga caaaaccatt acgcttatcc
      721 acttcacgat tcccccctac agtagcatct gccgtcaaga caatcgcttt ataaccttca
      781 gccttcacac ggtccatgat gtggcggttg ataccgtcat ccttactaaa gtaaaattga
      841 aaccaatgag gtgtcccttg aagggcttca gaaatctctg gaaggtcaac agtagagtaa
      901 gaactggttg tataaagaga accaaactca tgcacaccac gcgcagtcgc cacttccccc
      961 tgttcattcg ctaatttatg ggccgcaaca ggcgccataa tgattggtga agatagtttt
     1021 tcacctgcaa attcaatctc tgtacttgga ttttcaacat cgcaaagtgt atgaggaacg
     1081 atgagtttgt ggttaaaggc gcggatattc tctcttaaag tgaaagtatc ttccgcccca
     1141 ctagcgatat agccaaatgc tgctttagga ataacttgtt gcgccattgg ctccaaatca
     1201 taggtattga tgaagtctac atgaccttct gcattgcttg ttttgtatga cataaaatgc
     1261 cctccttgat taagtaagcg tttgcttttt actacacaac tataataact cttttttcaa
     1321 tcattttcaa gagttttgct taaaaaccat cttatttttt catacaatat actagcccta
     1381 ctttccttaa actctaaact ttagtctata ttaagtgaat cgttgagatt ttttgctgcc
     1441 aggcatttga actacttttt tatttgcgga ttctatctac taatactata aaaaaacaag
     1501 tgaataagac accagaacat cctctaatag gacctatgga cttatatcag tcccatatat
     1561 actgtttaag caagatacta tcctagttga cgctaacttc ctatcccact tattaatttt
     1621 ttatttatag tgaatctgaa caaatcaatt gggaaatcca agtcaatttc tagtactttt
     1681 tgaacagttt cagcgtacta tcgtaaaatg aaataaaaca tgcacaaatt gattagggaa
     1741 tttaaaccaa tttctaacag tgtcttagaa atcaaagtgt actatttcaa cttcaatata
     1801 ctacacttca ttttctcctt aaattcagtc tctttttgaa tcaaaaaatc ccctggtaag
     1861 agccagaggg taagaattta tttcattgtt gggaagagca atacatcacg gatagttgtt
     1921 gtatcagtga ggagcatgca gagacggtcg ataccgattc ccaaaccacc tgttggtggc
     1981 ataccgtatt caagagcctc gatgtagtca tagtcgatgc ctgtcgcttc atcatcacca
     2041 agttctttag ctttagcttg ggcttcaaaa cggctaagtt gatcgattgg gtcgttcaac
     2101 tcagtaaagg cattaccgta ctccttagtc atgataaaga gctcgaaacg gtcagtaaag
     2161 cgttggtctt caggattttt cttagcgagt ggagatacag ctactggatg tccatagaca
     2221 aaggttggtt ggattaaagt ttcttcgaca aactcttcaa agaaggcatt gatgatgtga
     2281 ccaacctcag tgtagtgttt ctcaactgga actttcttct cagcagcgat agctttagct
     2341 tcttccaaag tcatgtcttg ccagaaatcg acaccagtaa tttctctgat agcatccacc
     2401 atatgaacac gcttaaatgg tttgttaatc ttgatttcag taccttggta gttgactggg
     2461 ccatcacctt tgactgattt agcagcgtgt tggataatgc cttccgtcaa gtccatgatg
     2521 tcttggaaat ctgcataagc ttggtaaact tcgatagaag taaactcagg gttatgagta
     2581 gcgtccattc cttcgttacg gaagatacgg ccaatttcat agacacgttc cataccaccc
     2641 acgataaggc gttttaagtg aagctcagtc gcgatacgaa gcaccatgtc aatgttttgg
     2701 gcattgtggt gggtgataaa tggacgggca gcagcaccac cggcttcatt atgaagaaca
     2761 ggtgtttcca cttcaaggaa tcctttttgg tcaaggtaac gacggatttc agagatgatt
     2821 tttgaacgag tgacaaagcg ttcaaagctt tcacgattag aaatcaagtc aaggtaacgt
     2881 ttacggtaaa ttgtttcaac gtctgtcaaa ccatggaatt tctcaggaag aggacgaaga
     2941 gccttagaca agtgtgtgat gtgggttgcc ttgatagaga gttctcccat atccgtacgc
     3001 atcacttcac cttcgacacc aaggaagtca ccaaggtctg cttttttgaa gatttcgtag
     3061 ttttcttcac cgacagcatc cttacgaaca tagatctgaa tctggccttc gcggtcttga
     3121 aggtgggcaa aaccaacttt tcctttacca cgtttggtta ccaagcgtcc tgcgatagta
     3181 gctgtttcgt ttttatcgtg taattgttct ttatcgaggt tggcatattt atcttttaat
     3241 tcttgtgaat ttgcagtacg ttcaaaacgt tttccgaaag gatcgattcc ttgttcgcgg
     3301 agcgcagcca ttttttcacg gcgaacgatc tgctggtcat ttagttcttc catatgttct
     3361 gtagacatgg gatcctccta gttttactca aaattgaata cgatgagtca ttttttgcga
     3421 tacccccatt ttatcataaa taagcaagaa attcacggat aatctttaaa aactaaaaag
     3481 aacctgacgc taaaatcact ggaaagaagt gaaagtatct tccgccccac tagcgatata
     3541 gccaaatgct gctttaggaa taacttgttg cgccattggc tccaaatcat aggtattgat
     3601 gaaatctaca tgaccttctg cattgcttgt tttgtatgac ataaaatgcc ctccttgata
     3661 agtaagcgtt tactttgtat attgcagttt ggggaagttt gggatccttt ctgctcggtt
     3721 taatcgttag tatcatccga cattatcgaa tccctgtttt ggcgcaagta gcgacagcct
     3781 acattgaatt gtcacgtaat acgccccttt tgattcaact cttctttctc tacttcggtc
     3841 ttccccgaat cgggattgtc ctatcttcag aagtctgtgc aacgcttggg cttgtctttt
     3901 taggaggctc cgccatgcag gattcgggaa tccaagtact ctttcaagga aataacctcc
     3961 tgagaatctt acagggattg ggcgttacga ttgggatatc catcctgtct gtcctcttat
     4021 ccatgatgtt cggaacagtc atgggaatca tcatgacctc ccattctaga atcatacgat
     4081 ttttaacacg attgtatctg gaatttatcc gtatcatgcc ccagctggtg ctactcttca
     4141 tcgtttactt tggcttggct cgaaacttta atatcaatat ctcaggtgag acttcagtta
     4201 ttatcgtttt taccctctgg ggaacagctg aaatgggaga cttggtacgt ggagctatca
     4261 cttctctccc taaacatcag tttgaaagtg gacaggcact cggcttgact aatgttcaac
     4321 tttactacca catcatcatc ccacaagtct tgagaagact gctaccgcag gctatcaatc
     4381 ttgtcactcg gatgattaaa accacttcat tagttgtttt gattggggtt gtggaagtga
     4441 ccaaagttgg acaacaaatc atcgatagca atcgcctgac catcccaact acttcatttt
     4501 ggatttatgg aaccattcta atcttatatt tcgcagtttg ctaccctatt tccaaactat
     4561 ccactcactt agaaaaacat tggagaaact aaatgtctga aactatctta gaaatcaagg
     4621 aactaaaaaa atccttcgga gacaatccca tcctccaagg actttctcta gaaatcaaaa
     4681 aaggggaagt tgttgtcatc ctagggccat ctggttgtgg gaaaagtacc ctccttcgtt
     4741 gcctcaacgg cttagaaagt attcaaggtg gagatattct tctggatggt cagtctatcg
     4801 ttgaaaataa aaaagatttt cacctagttc gccaaaagat tggcatggtc ttttaaagtt
     4861 atgaactctt tccccatctg gatgtcttac aaaacctcat cctaggccct atcaaaactc
     4921 aaggatggga caagaaagaa gtaacggaag aagctttgca attactagat cgtgtcggtt
     4981 tgctggataa acaacatagc tttgcccgtc aattatctgg tggacagaag caacgtgttg
     5041 caattgtccg tgccctccta atgcatccag aaatcatcct ttttgacgag gtgactgctt
     5101 cgctggatcc agaaatggtg cgtgaggtgc tggaacttat caatgatttg gcccaagaag
     5161 gccgtaccat gattttagta acccacgaaa tgcagtttgc ccaagccatt gctgaccgga
     5221 ttatcttcct cgaccaaggg aaaatcgctg aagaaggaac agctcaagcc ttctttacca
     5281 atccgcaaac caaacgagcc caggaatttt taaacgtctt tgactttagc caattcggct
     5341 catatctata aaggagattc ttatgaaact attcaaacca ctcttaactg ttttagcact
     5401 tgcctttgcc cttatcttta tcactgcttg tagctcaggt ggaaacgctg gttcatcctc
     5461 tggaaaaaca actgccaaag ctcgcactat cgatgaaatc aaaaaaagcg gtgaactgcg
     5521 aatcgccgtg tttggagata aaaaaccgtt tggctacgtt gacaatgatg gttcttacca
     5581 aggctacgat attgaactag ggaaccaact agctcaagac cttggtgtca aggttaaata
     5641 catttcagtc gatgctgcca accgtgcgga atacttgatt tcaaacaagg tagatattac
     5701 tcttgctaac tttacagtaa ctgacgaacg taagaaacaa gttgattttg cccttccata
     5761 tatgaaagtt tctctgggtg tcgtatcacc taagactggt ctcattacag acgtcaaaca
     5821 acttgaaggt aaaaccttaa ttgtcacaaa aggaacgact gctgagactt attttgaaaa
     5881 gaatcatcca gaaatcaaac tccaaaaata cgaccaatac agtgactctt accaagctct
     5941 tcttgacgga cgtggagatg ccttttcaac tgacaatacg gaagttctag cttgggcgct
     6001 tgaaaataaa ggatttgaag taggaattac ttccctcggt gatcccgata ccattgcggc
     6061 agcagttcaa aaaggcaacc aagaattgct agacttcatc aataaagata ttgaaaaatt
     6121 aggcaaggaa aacttcttcc acaaggccta tgaaaaaaca cttcacccaa cctacggtga
     6181 cgctgctaaa gcagatgacc tggttgttga aggtggccat taactcttaa aagggactgg
     6241 attttaagct ccaatccctt tttaagattt tacctataac atcctgagtc tatctaagat
     6301 gttcaatctg aacacagtgt acatacttta tcttctattg catatacttt atcacataag
     6361 atacgaatat cctcttcact atgactagca atcaaaattg ttgtcccttt ttcactagag
     6421 agctttctaa acaatgttct catattttct acacttgatt tatccaaggc attcataggt
     6481 tcatctagta aaagaataga gggattctcc ataattgctt gagcaatccc tagctttttc
     6541 ctcataccta gcgaataagt tttaactttc tggtcttttt gctcatatag accaactatt
     6601 ttcagtgtat cattgatttc ctgattacca actactcctc gtatgcttgc caaatattgt
     6661 aaattcttaa agccactata ataatttata aaaccaggtt cttcaatcaa agctcccaaa
     6721 ttagctggaa tttttctctc aggaacaata ttttccccat tgattaacac ttctccataa
     6781 gacggactat ataaaccagc tattaattta aacaatacac ttttccctga gccattcgca
     6841 ccagtgattc ctatgatttc ccctggttta caactaaagt taaggttttg aaaaacacat
     6901 gtctttttta atttcaactc aatatttttt aatatgatta tttcattcat tctataaacc
     6961 tcctcttttg acgagtgaaa tagaaaatac ttttaaaaag aaagactaaa aatagcaact
     7021 gaagaaataa atctcgtcct atatctccat tccctcgatt caaaatataa aatagataat
     7081 tagttcgatt ccctacaaat agaccaccaa acacaatcat gagtaaaaag aaactaacgc
     7141 aagcaaagtt catttgtaca ttcgctccta gtgcgtataa cataaagcaa agcaaggata
     7201 gcacacaagc attcaaagaa tcaactataa acaaaactcc tatatcccag tttggtaact
     7261 gtaacataaa ttgaatcact agaactttta ccatgattaa aatgagtcca taaagaaaac
     7321 aggtccaaat ctgataccta atccagagct taatagaaga aaatcgaatc acttccataa
     7381 agaaatcgga tgctcttcta cgatatacaa ctgctagaaa aaatgtatga ataataaacc
     7441 aatgaagcaa ccatatggat aagactaaaa aagagttttg actcagatta ggccctttta
     7501 aaatttctat aacaagtcta tcatttcctt ctaaccaata ccataatcct aaacaaatca
     7561 atatccaaaa aagaacataa ccccaaaagt acttggtata gattatctga ttcaacctcc
     7621 acatgtaact acttaacttt cccatttcca acttttacac tctcctccag tttctatgaa
     7681 cagaaaatac agtcaatgga attatgatag atagtaatgt aagccaataa atcaatgcat
     7741 acggattgga atttaccata tactgaaaaa ttggcaataa tccaattatc ccattgtcca
     7801 actgataaat ccagaataag gattctacaa ataaaaaagt aaacagaaat actaagctca
     7861 tgtttgattt tttaaaccaa gaaaaactgc taatagtaag taaggataaa aagaaatagt
     7921 atgctatata agagaaaaaa aatcctataa agaaactagc attgtttgca atacttatac
     7981 cataaaattc tcttaaaaaa tcaacctcct ttatctccaa agagaagcta aaaccattac
     8041 taaatgcaat tagaaaaatc aataaaaata aagtcgccgt ccaaatcccc gtactaagag
     8101 ctgctaattt gaaactaaaa ctggtaaagt gcttaattga tttcagacga atgcgacact
     8161 ccaacctatt aaaatagtta ttcatcaaat aaaaaaagaa caatatatat gtgaacggaa
     8221 agcaatatac tccagtcgtc atatcttgaa gtaaaactaa gatccattct aatacatttg
     8281 gatggattga atattggcga cagcgcaata aatatactgt actagataaa acacaggata
     8341 gcagtaatat aaaataaacc aatactgcta agaaatcttt tttataaaat tgaacaaatt
     8401 gtttcattat acgtagtcct ctgaatgtag aaaaaatgta ccataaacaa ccaaacaact
     8461 aacaaataaa ataaaagcaa gatgcccact aactaaggaa agactgatat ctttctgata
     8521 tcccaaagct aatgttgtca caggttctaa gtaagatagc cctaaaatag cccaaaaaat
     8581 accaccaacc atcatatagg caactgggat gaaaatagct cctatttttt tcttcactag
     8641 caaagcacta gctagtccaa aaatagagaa cacagcgccc caaactccat accagagagt
     8701 cgtcacaaga ctatagagca actgattaga atcaaataat tcttttaagg caccactata
     8761 atctccaata taaatttcct gataaggagt cactaaaaga ttaattccta ataataataa
     8821 ataggggaga aaaaagacta gaaaagaaga aataattgca gtactaccca caatagctag
     8881 atacctcttt ttagaaattc ggcacaattg tgctgttaga aaatgactct cagcatcctc
     8941 tattatctga ctagaatagg gcagtgtaca gataagtgca gctactaggc taatcggtga
     9001 aaatcctcga atagaagaag cggcaaaaaa aatcgataaa ccttcaattt tataaatacc
     9061 attgaaagca aggaaatttc ctaaactcat gcaaagaagg gtcaaaaata aagacatata
     9121 aaatcgaggt gattgaacga ctcgtacaag attacaaatg aaaaattcca tccttactcc
     9181 tccttataat aaaaataggg tgtagcattc ttttttcatg ctacacccac aatcaaccat
     9241 ctttaaggct tactctgaca agtaagttaa taagaatctg gactccaaga acctgaagta
     9301 tgaattctta catgatttcc aaattgtggc gccatagcta atctagtacc agaaccaata
     9361 taattgtcac cacctccatt atagtacatg acaatcctag agccagaccc caatgaatat
     9421 accggggtaa tatctgaccc actataggcg cgctacgaat agaggtattt aaccttttac
     9481 cgccaccagt gctgtcacta ttattaattc cagcagaggc gttttctttc tcaagctcac
     9541 tagttgtatc cgaaccccaa cgcggcaacg ttaaatcata atttccaatc tgtctagcta
     9601 aaactgtagg gagaaacaaa ctagatgcaa ttgtaactac gcaaaaaagg aatatatttt
     9661 tcttcttttc atgatatcgt cctcctaaga agtgataaac aagatagttg attgatcaat
     9721 ttgatacata ttacattttc attatatcaa taaaagaaag cgttgtcaat tattttattt
     9781 aaaatattgt catattttaa ataaaatggt aaaagaggct cggtagcctc gtctctcttt
     9841 atcttactga cctaaccttc ttgccaattt tcttggtcgt ctttaaagcg ttttagaaga
     9901 tcaaggccct ctggcgtgat gtaaccttct tcttgggcta gatggataag ctcgctatag
     9961 tttgaaagcg tcacaagttt aacaccagca tctgcaaagt tcttatctgc ttttggcaat
    10021 tggtagctga aaatcgctac aactccaagc acatctgctc cttctcgctt ggctgctgct
    10081 acagcttcaa gaactgaacc acccgttgaa ataaggtctt caaccactac cattttttga
    10141 ccttgagcta cgcgaccttc gatttgatta ccagctccat ggtcttttgg tttgctacgg
    10201 atgtaggcaa aaggcaagtc catcttatca gcaataatgg ctccgtgtgg aatccctgct
    10261 gttgcagttc ctgcaatcac ttctacttca ggaaaggctt ctttgatagc ttccacaaaa
    10321 ccattttcaa ttagggtacg agtttctgga taggctagtg tcacacgatt atcagtgtaa
    10381 atcggtgact tgataccaga tgcccaagtg aagggttcct ctggtttgag gtaaacggct
    10441 tggattttca agaggtggct agcgatatct ttagcaagtg tcatggtatt ctccttttat
    10501 ttttctaatc tagttcttta attccagtcc tgtgtccatt catccttgat ggcatgataa
    10561 gctgcaacag gatcctcagc ttgggtaatg ggacgtccca ctacgatata gtcactgccg
    10621 atttgatagg catcagcagg tgtcatgact cgtttttgat ctccaactgc aacaccagct
    10681 ggacgaatcc ctggtgtcag acagataaaa tctggattgg tagcctgctt gatgacttgt
    10741 acttcctgag ccgagcaaac aacaccatcc aagccagctt cagctgtctt cttggcatag
    10801 tgaatcacag actcttgcag actggtttgg atattttgaa actcctgcat ctgagcttct
    10861 gacgttgatg tgagctgagt tacagcgatc aatttggctt gacttccaag accttcacgc
    10921 gcagccttca tcatctctac accaccagcc gcatgaacat tggtcatatc cacaccaagc
    10981 tgagatagga tcttcattgc tgacttgact gtattaggaa tgtcatgaag tttgagatcc
    11041 aaaaagacac tatgacccaa accttttaag taggacacaa tctcaggccc cgctgcgtaa
    11101 taaagctcca tccctacctt gagataaagg ctttcttctg ctgggaaaag agctaaaaat
    11161 tccttgaccg cctcaaaact aggaaaatca agagcaatga ttggacgatg ttctcgcata
    11221 ggtttctcct tttaccttta ctagtgagag agtctggcca acagaagcca cgaaaaaagg
    11281 aacctgccaa cagcaaggtt ccacgaaaaa tgggtagtct ccaccctttc accgtctaac
    11341 cttagctgcc tctctggact gctttaaagg ttttttacta ttctattatt tctactagca
    11401 cttgtcaagt aaaaacatgg tcacgtatgt gttgactgct attgaacacc tcacaagact
    11461 ctttccaaaa gaatagttaa agactttcac ttaggacaga gaaaaagagt ttgcttgtta
    11521 ccctttaatt gaacaaatgg gaattctgtt ttattttgcg gatgcctatt catcttggca
    11581 aaggggaagt aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg
    11641 gcaacaatta ccgaaaaaat ccttaatggt gctttgctag cttattaatc accgtcccca
    11701 aaaatacttg gattacaaga caggttttga agcacttata gaggagattt aaaaatgttg
    11761 cattttttat tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag
    11821 cactattgtt atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc
    11881 tgtagaattg ctgtcaaaaa gatcagttca tttttccttc ccacttgtgt ttataatcat
    11941 taaaataact caattaagaa attttctttt tcctaatagt tatcgtaatt aaagttaata
    12001 gaagaacaat ccaaataagt agtgttagat taggaattag agtttcattc catgaaaatc
    12061 cctcccattt tgtgaaaaac ttagtaaaca gtcccataaa actataatct gttatcttcg
    12121 caactgtctt atccaaacca gatagcatcg gtaagaaagc aactaaaatc atagcaggaa
    12181 gactgataac ctgagctact acttggctct tcgcggttaa acctatcaat aaatagaata
    12241 aaatgatgga taaagaggtt agaagaacga ttgtaatata attaaaagta tgtacaattg
    12301 taactcctaa aataagagga gtagttccca taatcacaaa agttagcaaa aaaggaagaa
    12361 acatcgttga taaaatgtat tcggatcctt taacaccact caacagaaga gtttgtaaat
    12421 tgtacttttc tttttcttca gacaagataa tagttatagg acttccaaca gccaaagcca
    12481 aagaaaaagg taaacacatc atcaaaagaa ctaatgcctg ttgatcgttg accttcccct
    12541 gtgtttccat aagatattta taaaaatatg tgaaagcaaa aggcactaaa acttgcaata
    12601 aaatactctt attggaaagg ataatttgac aacgcaacca taccaaagcc agaaaccgtt
    12661 taagcattta gctttcctcc tgttaatgtg ataaaaatat cttctaaagt aggctcacat
    12721 gaatgaattg aaaaaatatt ttccagatca gcctgagata cctgttctag tgatgtaaaa
    12781 tcaaaagtta tctgattccc attataatct gtaaccttaa tctttttatc tttattatat
    12841 ctttgaatga gttcagaagg agctccttgc tcaactaatt tccctttatt taataaggca
    12901 acataatcac ataaaagagt tgcttcattc atatcatgag tcgttagaaa aatcgttgtc
    12961 cctgctgttt tcaattctaa aattaactca tgaattgttc gagaagttgt gggatctaga
    13021 cctgaggtcg gttcatccag aaagagtaca gcgggtttgt tgataagagc tcgtgctaaa
    13081 agcattcgtt gcctcattcc agtggataat tttcctgcta ccatcttgca actatcatat
    13141 aatcctactc gctttaacaa attatcaaca cgtaatttac taatattata aaatttacta
    13201 taaaaaagaa gattgttata cagagacatt ttctcataaa atccacttgt atcgctaacc
    13261 aatccaattc tctttaattc accgcttgtt aaattttgag atttttgtcc caaaataata
    13321 gattgtcctt tatcggcaag gagctgccca gtcagaatat taatcgttgt ggtctttcca
    13381 gaaccagatg gtcctaaaaa tccaaaaatc tgaccttctt taacagtgaa acttatatca
    13441 tttaaagcta ttttatcacc aaaacttttt gataaatggc taacttcaat catactcatt
    13501 gcccctcctt tatattctac atttttactt aacatctatt tacttagctt tatcaaataa
    13561 acgtcttaa
//
LOCUS       DAVKUR010000051        13116 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKUR010000051 DAVKUR010000000
VERSION     DAVKUR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.051"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1125
                     /locus_tag="VW749_001701"
                     /pseudo
     CDS             1..1125
                     /locus_tag="VW749_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1211..2413)
                     /gene="rpsA"
                     /locus_tag="VW749_001702"
     CDS             complement(1211..2413)
                     /gene="rpsA"
                     /locus_tag="VW749_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0175706.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2575..2646)
                     /locus_tag="VW749_001703"
     tRNA            complement(2575..2646)
                     /locus_tag="VW749_001703"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2612..2614),aa:Gln,seq:ttg)
     gene            complement(2656..2736)
                     /locus_tag="VW749_001704"
     tRNA            complement(2656..2736)
                     /locus_tag="VW749_001704"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2700..2702),aa:Tyr,seq:gta)
     gene            complement(2786..3016)
                     /locus_tag="VW749_001705"
     CDS             complement(2786..3016)
                     /locus_tag="VW749_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0175707.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3184..3828)
                     /gene="pcp"
                     /locus_tag="VW749_001706"
     CDS             complement(3184..3828)
                     /gene="pcp"
                     /locus_tag="VW749_001706"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0175708.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3843..4766)
                     /locus_tag="VW749_001707"
     CDS             complement(3843..4766)
                     /locus_tag="VW749_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0175709.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4763..5452)
                     /locus_tag="VW749_001708"
     CDS             complement(4763..5452)
                     /locus_tag="VW749_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0175710.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5517..6221)
                     /locus_tag="VW749_001709"
     CDS             complement(5517..6221)
                     /locus_tag="VW749_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0175711.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(6277..7299)
                     /locus_tag="VW749_001710"
     CDS             complement(6277..7299)
                     /locus_tag="VW749_001710"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0175712.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7429..9900)
                     /gene="parC"
                     /locus_tag="VW749_001711"
     CDS             complement(7429..9900)
                     /gene="parC"
                     /locus_tag="VW749_001711"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0175713.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10320..12263)
                     /gene="parE"
                     /locus_tag="VW749_001712"
     CDS             complement(10320..12263)
                     /gene="parE"
                     /locus_tag="VW749_001712"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0175714.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12399..13040
                     /gene="plsY"
                     /locus_tag="VW749_001713"
     CDS             12399..13040
                     /gene="plsY"
                     /locus_tag="VW749_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0175715.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3802 a         2968 c         2309 g         4037 t
ORIGIN      
        1 gtatgcctac tagaattctc cttagaaagc gtcgtttcaa gtgctatcac tgttcaaaaa
       61 tgatggttgc tgagactccc ctggtaaaga aaaatcacca aatccctcgt atcatcaacc
      121 aaaagattgc tcaaaagtta attgaaaaga tttctatgac cgatattgcc catcagcttt
      181 ccatctcaac ttcaactgtc attcgaaagc tcaatgactt ccactttgag tgtaatttta
      241 gaaatctgcc taagattatg tcttgggacg ttgaaacagt ccggggagtg actgtttcaa
      301 tcgggagatg gagatgagct ttattgcgca agattttgaa aagctcgata tcatcactgt
      361 tcttgaaggt agaacacaag ctgccatccg agatcacttt cttaaatatg atagagccgt
      421 ccgatgtcgc gtcaaaatca ttactatgga tatgtttagc ccttactatg acttggctaa
      481 acagcttcgc tttcaaattt ctaggctcag gctgaaacag tctcccagac tgtttcactc
      541 ccgaatgctg aaatcgttct tgatcgcttt cacattgtac aacatcttag ccgtgctatg
      601 agtcgtgtgc gtgttcaaat catgaatcag tttgaacgaa aatcccatga atacaaggct
      661 atcaagcgct actggaagct catacaacag gatagccgta aactgagtga taagcgattt
      721 tatcgtccta cttttcgtat gcacttaacc aataaagaga ttttagacaa gcttttgagc
      781 tattcagaag acttgaaaca ccactatcag ctctatcaac tcttgctgtt tcactttcag
      841 aataagaaac cggagaaatt tttcggactc attgaggaca atctaaagca ggttcatcct
      901 atttttcaga ctgtctttaa aaccttcctc aaagataaag aaaagattgt caacgccctt
      961 caactacact attctaatgc caaactggaa gcgaccaata atctcatcaa acttatcaag
     1021 cgcaatgcct ttggttttcg gaactttgaa aacttcaaaa aacggatttt catcgctctg
     1081 aatatcaaaa aagaaaggac gaaatttgtc ctttctcgag cttagctttt tttcaaccca
     1141 ctacagttga caaagagcca gaaaaatcct ttgtttagta aacaaaggat tttgtgaatt
     1201 ttcaatttga ttaaagttcg atatcaccaa acaaatcagc cattgaaaat cctgtttgtg
     1261 tttctggaag ttcgaaatca cgcttttctt gacgtcttgg acgacgtgga cgagcaacac
     1321 gtttttcttc tttttgtcct tcttcttggg ctggacgttc ttcaagagct ttaatagaaa
     1381 gtgacacgcg ttctgcatct gcgttaactt caagaacttt aacttgaact tcttgaccaa
     1441 ctttaagagc ttcttttgga ttttcaatcc gtttgtgtga aatttgtgat acgtgaacaa
     1501 gtccatcgat acctggcaat acttcaacaa atgcaccgaa gtcagtcaaa cgtttaactg
     1561 ttccttctac tacatcacct ttagccaatt tttgctcaac gccatcccat ggtcctggta
     1621 ctgttgcttt aagtgaaagt gatacacgtc cttcttcttc gttaagatca aggattttca
     1681 cttcaatttc ttcaccaaca gttacaactg attttggtga tacattacgt tcatgtgaca
     1741 attcagtcaa gtgaaccaat ccgtcaacac caccaagatc gacgaaagcg ccgaagcttg
     1801 tgatacgagc aactttacca gttacaacat caccaacagc caatttaccg aatacttcag
     1861 cgcgagctgc tgcagtagct gcttcaacaa cttcacgacg tgaaaggatg aagcggtttt
     1921 ctttagcgtt aacttctttg attttagtat caaattcttg acctacaaaa cgctcagcgt
     1981 tacgtacgaa acgagtatcc aacattgaag ctgggataaa tccacgaaca ccttcaaatt
     2041 ctactgaaag tccaccttta acggcacgcg ttcctttaac agtaacaact tcttcttcgc
     2101 gaccaacaag tttgtcccat gctttgcgag cttcaaggcg ttttttagat acaaggtatg
     2161 taactgtatc agtatcttta ccaactactt gacgaagtac aagaacatcc aatacttctc
     2221 ctactttaac aaagtcattg atatctgcat cacgatcgtt tgtcaattcg cgaagagtca
     2281 agacaccttc aacaccagtt ccagagattg caacgttagc ttgagtcgca tcaactgtca
     2341 atacttcagc actaacaaca tcaccagtct caacttgact aacgctattt agcaaatctt
     2401 caaattcatt catctaaaaa atcctccaac aatcaagttt ttcttaaact tgacatactt
     2461 ataatttttt tcctaagcac ccgcaaggac atgttcatat cattcacgtc tttcaattat
     2521 aaaaataaaa taccctaaga tattttgctt tttatcttga ttattaccta agaactgggg
     2581 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
     2641 accccattaa tgaaatggag agagagggat tcgaaccccc gaacccgaag gagcggattt
     2701 acagtccgcc gcgtttagcc tcttcgctat ctctcctaca atcaacatgg actattatat
     2761 catgaaaatt tcaaaaaaac aagacttatt ttgctaaatt ataattttca atcaaaattt
     2821 ccacagcttt ttccaatttt ttataaaaac tatcgacatt cccattcttt ataatggcaa
     2881 attgtccgtc taattcggca atttctccga taactttttt accgatagtc aatgtataac
     2941 cttcaaaact gtctttacca acattaactt tggcatccgc tacttgaatt tcgatttttt
     3001 tatctttctt gctcatttca tacctctctt cactttttct attttacaag aaaatcctaa
     3061 aactagcaag aaaaaactct atatcaggct tctctgatat agagttttat gtaaacaacc
     3121 tcaatcgatt tagcatagtt aatagttagt aaacaagcat aattgactat cctttttagg
     3181 ttatcagtga gtctcaccgc ctactaactg caaatcctta tctttgtagt ctacaatagc
     3241 ttcaatagct acctctatgc ctcttacaat atcacataga ctcattcctg cagtattcgg
     3301 cttatttact acttgttcca tcatatatgg aatatgcatg aaacctgctc tcatattagg
     3361 gaatttttta tccactaaat aaagagcttg gtacatcaaa tgattgcaaa caaaggttcc
     3421 tgcactattg gatacaactg ccggaagtcc ctgttttttg atagcttgta ccatcgcttt
     3481 gataggtaaa ctactaaaat aggccgatgc tccatcaata cgaatcggtg tatcaattgg
     3541 ttgattgcct tcgttatcag gtatgcgagc atcatcttga ttaatagcca ctcgttcagg
     3601 tgttaagccg gtcctgccgc ctgcttgtcc aatacaaagt acagcatctg gttgatatcg
     3661 taatatttct gcctctaaaa cttctgacga cttataaaaa accgttggaa tttctaccca
     3721 gcgaacttca gccccattaa tctcagatgg taataatttt acagcctcca aagctggatt
     3781 aatcttttca cctccaaaag gattaaaacc tgtaaccaat attttcattt tattttcctt
     3841 tactaaaatg cgagaaagta cattaagaat atgtgaataa caatcattac tagagcaaca
     3901 cctgcttgag cctttataac gccattctga tctttcatat ccatcaatgc tgctggtaga
     3961 gcgttaaaat tagcagccat tggggtcaat aaggtcccac aataacctgc tgtcatggca
     4021 agagcaccag ccacaattgg attagctccc agagcaaata cgaagggaac tccaacacct
     4081 gctgtaataa cggtgaatgc tgcaaaagca tttcccataa tcattgtgaa tagaaccatt
     4141 ccaagaacat aggccaaaac tcctataaag cgactatctg aaggaacaat accgctaatc
     4201 agatgagaga taacatcacc aacacctgct acagtaaaaa tagcccccaa agcccctaat
     4261 aattgaggaa caatcccact tgttgaaact tgctgagtca ttcgattatt ttctgataac
     4321 agactcttag ggtgactatt ggtaatcaca agaacagaaa ttgtagcaaa caaggcggca
     4381 aggctaatcg aaatcttgct aaattctgga atcatttgcg ctaagaccaa cgcaagtatt
     4441 gccatcagca taactggaat aaaaatttta tttttcaacc tgttagattc aatattggct
     4501 ttcatttcat ctaaggatgg caaggttccg atacggactt gcttaaacaa tgttaacagc
     4561 gataatagga ttacaataat accaatactc atatttggca tataggaacc acctataaac
     4621 gtaatagaca atagagtcca aaatgcagat gtcccaagtc gaactgggtt tgttttatct
     4681 ttataactac aataggctgt atggagaaat tgacaaccaa tcacaatata ggtcaactct
     4741 aatagttgct ttgccaactc tgtcattttt gttctcctcc cctagtcttt tttgatatca
     4801 attttttatc aaataaataa ttgtaaatcc ccactacaat aagtgttata acagcaacaa
     4861 taatagatgt agaagcaatc cctgcataat tgctttcata gcctaactga tctaatgttc
     4921 cccctatcaa gaggactccc ccagcaccta caaacgtatt ttgagcaaag aaatttccaa
     4981 aattttcatt cgcagccgca cgcgctttta ttgtctcatc ttcaacctct gttaactttc
     5041 tacctaattg agactctgca gctgcttctc ccataggttg aaccaaaggt ctgacaaact
     5101 gagggtgtcc tcctagacga attgaaaaga aaccagctaa ctctcgaata aagaaataaa
     5161 ctgtatagaa gtttccaact gtcagacctt taatctttcg aatcaaatcg attgatcgtt
     5221 gcttgagtcc aaaggtttct gacagcccca caagaggcaa ggtaaccata aaaatcgtga
     5281 gcactcgctg attgctaaat tcttttccca aaatctccaa aaattcaacg agagaaacac
     5341 ctgaaactaa agctgtaacc aaaccagcta agactactgt tgcaattgta tcaaatttta
     5401 aaataaaacc cacaacaatg attgctattc ctattaatct aatccactcc atatcaaact
     5461 cctttatatt caaaatgaca gtattttaaa aattttatca agatcaatac cattccttat
     5521 ttaatgtgtt tttctagttc tttttggtat ttgctattgg attccaattt ttctttttgc
     5581 cattttttaa aaacctcgtt atattctttt gttgtaacaa tatctttttg caatttcatt
     5641 cctttaaaga tatatggttc ccccttaata ccaacttgtg agtatggttt tgagaatggt
     5701 actacgttac ttacaattgg agaaccacca gatgaagctg ttggcatcaa taatgaacta
     5761 tctgtcgacc aagcttgagc tttggcatat ttttcatatc tcttctctag gtcagtggtc
     5821 tcagaaacag catcttctaa caatttctta tatttatcca aaccaggttt agctacaaca
     5881 tccttatctt ttcctttcgt aataccaagg tgtttcatgg cagaaccaga ttttggatcc
     5941 ataatattca agtaagacgc tggatcttga tagcttggag cccatcctgt actattcaaa
     6001 tcatagtctt tttgagaagg agcaacattg ccgtatttat cattttccat caaaccatca
     6061 ataacatttc caataacgtc tgtcgtcgat gttcgagtcg ttatactgta gcccaatgat
     6121 gctggatcta ctgcatagac ataagaaaat gttgtcggtg catctgcttc tttatcagtt
     6181 tttccacaag ccactaaaat agctaacgtg ctcaggacca ctcctgctgt taagagccac
     6241 tttttctatt tcataaaaaa tctcctttgg tttattttaa tctactttta caatccaacc
     6301 ttctggcgct tcaatatcgc caaactgaat acccgtcaat tcattatata atttacgcgt
     6361 cacaggacct acttctgttt cactatagaa tacatggaaa tcatcaccat gttgaatacc
     6421 tccaattgga gaaataaccg ctgctgtacc acaggcacct gcctctacaa aacggtcaag
     6481 attatcaatt ggaacatcac cctcaatagg agttaatccc aagcgatgtt ctgccaaata
     6541 aagcaaggaa tacttggtaa tagatggcaa gatagatgga ctcaatggtg ttacaaattc
     6601 attatcagct gtaattccaa agaaattagc tgatccgact tcttcaatct ttgtatgagt
     6661 tgatgggtcc agatagataa catctgagaa atggcgtgac ttggccattt ttcctggtaa
     6721 gagacttgca gcatagtttc caccaacctt agccgcacct gtaccatttg gtgctgcacg
     6781 gtcgtactca tcctgaatca agaagttggt tgggaccaaa ccacctttaa agtaatttcc
     6841 aactggcata gcaaagatgg tgaaaatgta ctcttctgcc ggttttaccc cgataatatc
     6901 tccgacacca atcaaaagag ggcgaagata taaggttcca cctattccgt atggtggtac
     6961 gtattcttca ttcgcacgga caactgcttt acaagcttct acaaacatgt ctgtcggaac
     7021 ttgtggcatc aagagacggt cacatgtacg ttgcaggcgt ttagcatttt catcaggacg
     7081 gaacagttga acactgccat ccttagtacg ataagctttc aaaccttcaa atgcttgttg
     7141 tccatagtga agacttggag aagactctga aatatgcaaa gttgcatcct ctgtaagctc
     7201 tccttgatcc cattgtccat ttttgaaatg agcaagatag cgataaggta atttcatata
     7261 ggaaaaaccg aggttttccc aatcaatcgt tactgtcata ttccactcct tattctaaaa
     7321 acctatttct tatattctac actatttttc taaaatagca agtatatttt gtaattttca
     7381 gaaaattcct ccaataaaaa ccatcttaga actgattctt catttcactt atttatcttc
     7441 agtaactact tcctgaagat aagcgtcaaa aacttcttca tctgaaatcg tgtcagaaat
     7501 gaagcttcca ttgctagtgc gttctgacaa gttcaagtct tgcaatcggc tttcatagat
     7561 tgttccttta ttggattgga caagcagagt ttggtcgttc acatccactt ccgtactgaa
     7621 gaaatcgcca acaaatcctt gctctgcaac tgctcctgcc aagaagacac gatgcggttt
     7681 gtttttcaac tcacgcaaga cttgtaatcc tcgtttggca cggctggttg ctagaatttc
     7741 ctcaatggaa acacgtttca agcttccacg ctgggtcaag aggtagaagg acgaagtatt
     7801 acagataaag ccagattgga ggacatcatc ttctttcaaa ttcatagcct tgacacctgc
     7861 tgccttagca ccgacaaccg gaacctcttc gatattgaaa cgcagggcat aaccattttg
     7921 actaaccaag acaacatcat ctagtttaat cggagccact gctacaatct gatctgtatc
     7981 gtctttgagc ttagcatact tgacagactt agatctatag gtccgccatg gagtgaattc
     8041 ttttcgctct acccgtttga tttgaccaag gcgagtcgct gcaaagtagg ttgtcgcatc
     8101 gtcaaactga tccagtactt ccacataaag gattgcttca ttcgtttcaa agtttgtgat
     8161 ggtttggctc agatgctctc cgatgtcctt ccaacgaata tctgccaact catggattgg
     8221 tctgtagatg acatttccaa gacttgtgaa catcaagagg tgctgggttg tcttggcaga
     8281 ttgaacaaaa atcaaacggt catcatcacg cttgccaatt tcttccaagg tggaagccgc
     8341 aaaggaacgt ggactggtac gcttgatgta acctgccttg gtcacgctga cgtaggtatc
     8401 ttcctcagcg ataagactag ctgtatcaat ctcaattgct ttcgcagtgt cttctaaaga
     8461 actcaaacga ggagttgcaa agttcttctt gacctcacga agttctttct tcatgagatt
     8521 gtacatagtc ctttcatcac cgataatagc cgccagcata gcaatcttct cacgaagctc
     8581 tgcttcttct tcctgcaaga caaccacatc ggtattggtc aaacggtaca gttgcaaagt
     8641 tacgatagcc tcagcctgtt cttccgtaaa atcatagcta actttgaggt tttccttggc
     8701 gtccgcctta ttctcagaag cacggataag agcaatgact tcatccaaaa tcgaaatcac
     8761 acgaatcaaa ccttcgacga tacggagacg tttctcagcc ttttctttgt caaagcgtga
     8821 acgcgccaaa atcacttctc gacggtgagc gatgtagcta gacaggattg gaacaatccc
     8881 aacctgacga ggtgtgaaat tgtcaatcgc caccatatta aagttgtagt tgatttgtag
     8941 gtcggtgtac ttaaataagt agttgagaac aagctcagta ttagcgtctt tcttaagttc
     9001 aatagcgata cgaagaccat cacggtcaga ctcatcacga acctcagcaa tcccagctac
     9061 cttgttatta acacgaacat catcgatttt cttgactaga ttggccttat tgatttcata
     9121 aggaatctca gtaataacga tttgttcctt accacctttt agcttttcaa tttcagtctt
     9181 ggaacgaaca accacgcgcc ctttcccagt ctcataggct ttcttgattt catcacgacc
     9241 ctgaataata gcccctgtag ggaagtctgg tccaggtaag aattccatga gtttatcaat
     9301 ctttgcagtt gggtggtcaa tcatgtaaac tgcagcatct atgacctcag ctaaattatg
     9361 gggaggaatg tctgtggcat aaccagccga aatcccagtc gaaccattga ccaagaggtt
     9421 tggaaaggct gctggcaaga ccgttggttc tttctccgta tcgtcaaagt tccatgcaaa
     9481 aggaactgtc tttttctcga tatcctgaag aaggtagcct gcaatttcag acaaacgtgc
     9541 ctcagtataa cgcatagccg caggaggatc tccgtccata gaaccgttat taccgtgcat
     9601 ttcaactaga atctcacgat ttttccagtt ctgtgacata cgaaccatgg catcatagat
     9661 agaagaatcc ccgtgtgggt ggaaattccc catgatgttc ccgactgact tggccgactt
     9721 acggtagctc ttgtcaaaag tattgctatc cttattcata gaataaagaa tacggcgttg
     9781 aaccggcttc aacccatcac gaatatctgg caaagcccgg tcttgaataa tgtacttgga
     9841 gtagcgacca aagcgctctc ccatgatgtc ctccagggac atgttttgaa tgttagacat
     9901 aagatacaaa gcccataaaa taccaagtga aaatagaaaa ttcttgaagt aagcaaactc
     9961 acaagagaat ttatcttttt cacacagtat ctagggcgtg ttcaactcct ttcaaagaat
    10021 gtagagtagg tttttatgca gtaaaagata ttttacggga attcgtcccg tgttcagtta
    10081 cgataagtaa ccaaactatc ctgtttgtat ttttcaatat gaaaatctgg ttttccaaaa
    10141 ttagtcttag tttgtgtctt aaccgctccc ttaagcgcct ctttaagata agcactcata
    10201 gcagattctt cattaataat cctgcaattt tttcaaacca agattttcaa actgcttttt
    10261 cacatagtca ttcacatccg actctaattt ccagtttact aacatattat tttctttcat
    10321 taaaacactg tcgcttcttc tagcgtaaac ttgacattat cttcaatcca tttacggcgt
    10381 ggttctacct tatctcccat gagaacattg acgcggcgtt cggcgcgcgc taaatcttca
    10441 attgtgacac ggatgagggt acgtgtttct gggttcatgg ttgtttccca gagctggtcc
    10501 gcattcatct caccaagtcc tttgtatcgt tggagggtag cgcctttacc gaactgttta
    10561 cggagttctt ctagttctcc gtccgtccaa gcgtaggcca cttcttcttt cttgccttta
    10621 cctttggaca tcttgtaaag aggtgggagg gcaatataga catgacctgc ctcgactagc
    10681 ggacgcatgt aacggtagaa aaatgtcaag agcaaggtct ggatatgggc accgtcggta
    10741 tccgcatcgg tcatgataat gatcttatca tagttggcat cttcaataga gaagtctgct
    10801 ccaacacccg caccaatggt ataaatcatg gtattgatct cttcattttt gaggatatcc
    10861 gccatcttgg ccttggctgt attgataacc ttaccacgaa gaggtagaat agcctggaac
    10921 ttgcggtcac gaccttgttt ggcagaacca ccggcagagt ccccctcaac tagatagagt
    10981 tcattcttag caggattctt agattgggct ggggtcaatt tcccagacaa caagccctta
    11041 tctttcttgt ttttcttccc atttcggctc tcatcacgcg ccttacgtgc tgcttcacga
    11101 gcatcacggg ccttgatagc cttgcggatg aggttagaag ctaattcccc attttccata
    11161 aggaaaaagg tcaacttatc agccactatt ccatccacaa ctgggcgagc tagggggctt
    11221 cctagtttat ccttggtctg tccttcaaac tgcaagtgtt cttcaggaac taagatagaa
    11281 agaacggccg ctagtccctc acgatagtct gaaccttcaa ggtttttatc tttttccttg
    11341 agaagacctg ttttacgtgc atagtcattc atgaccttgg taatggcaga cttgagtcct
    11401 gtctcgtgcg ttccaccgtc cttggtgcga acgttattga caaaggatag aatgttatct
    11461 gagaatccgt cattgtactg gagggctact tccacttgaa aaccattgtc ttccccttca
    11521 aagtaaagaa ctggcgtcaa gatttcctta tcttcgttga gataagaaac aaaatcttgt
    11581 actccattct catagtggaa ctcaatcgct tcatctgttc gcttgtccgt taaagacaag
    11641 gtcacatttt tcaagagaaa ggctgattca ttaaggcgct ctgaaatggt attgtacttg
    11701 aaatctgtcg tagaaaagat agtcgcgtca ggcataaaag taactttggt gcctgtttta
    11761 gacttgagtg ctgtaccgat tttcttcaaa gtcgtgacag gttttccacc attttcaaaa
    11821 cgttgcttgt aaactgcgcc atcacgggta atttcaactt ctaaccagct agaaagggcg
    11881 ttaacaacgg aagaacccac tccgtgaagt ccacctgatg tcttatagcc accttgaccg
    11941 aatttccctc cggcatgaag aatggtaaag ataacctcaa cagttggaat tcccatagcg
    12001 tgcatacctg tcggcatccc acgtccatgg tcttgaaccg ttagactacc gtctttattg
    12061 atagttacat caatacgatc accaaaccca gacaaggctt catcgactgc attatcaacg
    12121 atttcccaaa ctaggtgatg aagaccagcg ccatcggtcg atccaatata catccctgga
    12181 cgttttcgga ccgcatccaa cccttctagc acctgaatag catcatcatt ataattgtta
    12241 atattgattt ccttttttga cacaaggaac ctcctattcg ttcatcttta ctattctaca
    12301 ggttttccaa ggattttgca aaatttttct ttctccgatg tgacaatttc agcagagatt
    12361 ctctgctttt ctttcccaat tcatgatata ataggagtat gattacaata gttttattaa
    12421 tcctagccta tctgctgggt tcgattccat ctggtctctg gattggacaa gtattctttc
    12481 aaatcaatct acgcgagcat ggttctggta acactggaac gaccaacacc ttccgcattt
    12541 taggtaagaa agctggtatg gcaacctttg tgattgactt tttcaaagga accctagcaa
    12601 cgctgcttcc gattattttt catctacaag gcgtttctcc tctcatcttt ggacttttgg
    12661 ctgttatcgg ccataccttc cctatctttg caggatttaa aggtggtaag gctgtcgcaa
    12721 ccagtgctgg agtgattttc ggatttgcgc ctatcttctg tctctacctt gcgattatct
    12781 tctttggagc tctctatctt ggcagtatga tttcactgtc tagtgtcaca gcatcgatcg
    12841 cggctgttat cggggttctg ctctttccac tttttggttt tatcctgagt aactatgact
    12901 ctctcttcat cgctattatc ttagcacttg ctagtttgat tatcattcgt cataaggaca
    12961 atatagctcg tatcaaaaat aaaactgaaa atttggtccc ttggggattg aacctaaccc
    13021 atcaagatcc taaaaaataa aacgccagtt ctgtactgcc cccaaacagt tagacaaata
    13081 atttatccaa aggatttagt tctgtattgc acaggg
//
LOCUS       DAVKUR010000052        12618 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKUR010000052 DAVKUR010000000
VERSION     DAVKUR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12618
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.052"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            12..1148
                     /gene="dnaN"
                     /locus_tag="VW749_001714"
     CDS             12..1148
                     /gene="dnaN"
                     /locus_tag="VW749_001714"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0175716.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1213..1407
                     /locus_tag="VW749_001715"
     CDS             1213..1407
                     /locus_tag="VW749_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0175717.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1491..2606
                     /gene="ychF"
                     /locus_tag="VW749_001716"
     CDS             1491..2606
                     /gene="ychF"
                     /locus_tag="VW749_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0175718.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2677..3246
                     /locus_tag="VW749_001717"
     CDS             2677..3246
                     /locus_tag="VW749_001717"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0175719.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3247..6756
                     /gene="mfd"
                     /locus_tag="VW749_001718"
     CDS             3247..6756
                     /gene="mfd"
                     /locus_tag="VW749_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0175720.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6814..7080
                     /locus_tag="VW749_001719"
     CDS             6814..7080
                     /locus_tag="VW749_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0175721.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7073..7441
                     /locus_tag="VW749_001720"
     CDS             7073..7441
                     /locus_tag="VW749_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0175722.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGVVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7561..8829
                     /locus_tag="VW749_001721"
     CDS             7561..8829
                     /locus_tag="VW749_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0175723.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8826..10103
                     /gene="tilS"
                     /locus_tag="VW749_001722"
     CDS             8826..10103
                     /gene="tilS"
                     /locus_tag="VW749_001722"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0175724.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10107..10649
                     /gene="hpt"
                     /locus_tag="VW749_001723"
     CDS             10107..10649
                     /gene="hpt"
                     /locus_tag="VW749_001723"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0175725.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10665..>12618
                     /gene="ftsH"
                     /locus_tag="VW749_001724"
     CDS             10665..>12618
                     /gene="ftsH"
                     /locus_tag="VW749_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0175726.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         4346 a         1902 c         2563 g         3807 t
ORIGIN      
        1 aaggagaatc catgattcat ttttcaatta ataaaaattt atttctacaa gcattaaata
       61 ctactaagag agctattagt tctaaaaatg ccattcctat tttatcaaca ataaaaattg
      121 acgtgaccaa tgaaggtatt actttaattg gttcaaatgg tcaaatttca attgaaaatt
      181 ttatttctca aaaaaatgaa gatgctggtt tgttaattac ttctttaggt tcgatccttc
      241 ttgaagcttc tttctttatc aatgtagtat ctagtttacc tgatgtaact cttgatttta
      301 aagaaattga acaaaatcaa attgttttaa ccagtggcaa atcagaaatt accctaaaag
      361 gaaaagatag cgaacaatat ccacgaatcc aagaaatttc agcaagcact cctttaatac
      421 ttgaaacaaa attactcaag aaaattatta atgaaacagc ctttgctgca agtacacaag
      481 agagtcgtcc gattttaaca ggtgtccact tcgtattgag tcaacacaaa gagttaaaaa
      541 cagttgcaac agactctcat cgcctaagcc agaaaaaatt gactcttgaa aaaaatagtg
      601 atgattttga tgtcgtaatt cctagccgtt ctctacgcga attttcagcg gtatttacag
      661 atgatatcga aactgtagag attttctttg ccaataacca aatcctcttt agaagcgaaa
      721 atattagctt ctatactcgt ctcctagaag gaaactatcc tgatacagat cgcttgattc
      781 caacagactt taacactact attactttta atgtggtaaa cttacgccag tcaatggagc
      841 gtgcccgtct tttatcaagt gcgactcaaa atggtactgt gaaacttgaa attaaggatg
      901 gggttgttag cgcccatgtt cactctccag aagttggtaa agtaaacgaa gaaatcgata
      961 ctgatcaggt tactggtgaa gatttgacca ttagtttcaa cccaacttac ttgattgatt
     1021 ctcttaaagc tttaaatagc gaaaaggtga ccattagctt tatctcagct gttcgtccat
     1081 ttactcttgt gccagcagat actgacgaag acttcatgca gctcattaca ccagttcgta
     1141 caaattaagt gaaagaggtt gagcctggct cgcctctttt atgatataat cgaaaaagaa
     1201 aaggagagta gtatgtatca agttggaaat tttgttgaga tgaaaaaatc acacgcttgt
     1261 acaatcaagt cgactggtaa aaaggctaat cgttgggaaa ttacacgtgt aggagcagat
     1321 atcaaaataa aatgcagtaa ttgtgagcat gttgtcatga tggggcgata tgattttgag
     1381 cgaaaaatga ataaaattat tgactgagaa cccttagtta gagggttagc actttatccc
     1441 tttttgtgtt ataatattag ggattgaaat gaaaacggag aatgagaaat atggctttga
     1501 cagcaggtat cgttggtttg ccaaacgttg gtaaatcaac actatttaat gcaattacaa
     1561 aagcaggagc agaggcagca aactacccat ttgcgactat tgatccaaat gttggaatgg
     1621 tggaagttcc agatgaacgc ctacaaaaac taactgaaat gataactcct aaaaagacag
     1681 ttcccacaac atttgaattt acggatattg cagggattgt aaaaggagct tcaaaaggag
     1741 aagggctagg gaataaattc ttggccaata ttcgtgaagt agatgcgatt gttcacgtag
     1801 ttcgtgcttt tgatgatgaa aatgtgatgc gcgagcaagg acgtgaagac gcctttgtgg
     1861 atccacttgc agatattgac accattaacc tagaattgat tcttgcagac ttagaatcag
     1921 tcaataaacg atatgcgcgt gtagaaaaga tggcacgtac gcaaaaagat aaagaatcag
     1981 tagcagaatt caatgttctt caaaagatta aaccagtcct agaagacggg aaatcagctc
     2041 gtaccattga atttacagat gaggaacaaa aggttgtcaa aggtcttttc cttttgacga
     2101 ctaaaccagt tctttatgta gctaatgtgg acgaggatgt ggtttcagaa cctgactcta
     2161 tcgactatgt caaacaaatt cgtgaatttg cagcgacaga aaatgctgaa gtagtcgtta
     2221 tttctgcgcg tgctgaggaa gaaatttctg aattggatga tgaagataaa aaagagtttc
     2281 ttgaagccat tggtttgata gaatcaggtg tagataagtt gacgcgtgca gcttaccact
     2341 tgcttggatt gggaacttac ttcacagctg gtgaaaaaga agttcgcgct tggactttca
     2401 aacgtggtat gaaggctcct caagcagctg gtattatcca ctcagacttt gaaaaaggct
     2461 ttattcgtgc agtaaccatg tcatatgagg atctagtgaa atacgaatct gaaaaggccg
     2521 taaaagaagc tggacgcttg cgtgaagaag gaaaagaata tatcgttcaa gatggcgata
     2581 tcatggaatt ccgctttaat gtctaaaaat taataaatgg tgtcaattag gttggaaaaa
     2641 aattccaacc cttttggctt ttgaaaggaa aaataaatga ccaaattact tgtaggcttg
     2701 ggaaatccag gggataaata ttttgaaaca aaacacaatg ttggttttat gttgattgat
     2761 caactagcga agaaacagaa tgtcactttt acacacgata agatatttaa agctgaccta
     2821 gcatcctttt tcctaaatgg agaaaaaatt tatctggtta aaccaacgac ctttatgaat
     2881 gaaagtggaa aagcagttca tgctttatta acttactatg gtttggatat tgacgattta
     2941 cttatcattt acgatgatct tgacatggaa gttgggaaaa ttcgtttaag agcaaaaggc
     3001 tcagcaggtg gtcataatgg tatcaagtct attattcaac atataggaac tcaggtcttt
     3061 aaccgtgtta agattggaat tggaagacct aaaaatggta tgtcagttgt tcatcatgtt
     3121 ttgagtaagt ttgacaggga tgattatatc ggtattttac agtctgttga caaagttgac
     3181 gattctgtaa actactattt acaagagaaa aattttgaga aaacaatgca gaggtataac
     3241 ggataaatgg tgaccttatt agatttattc tcagaaaatg atcagattaa aaaatggcat
     3301 caaaatttaa ctgataagaa aagacaacta atacttggtt tatcaacatc tactaaggct
     3361 cttgcaattg caagcagttt agaaaaagaa gataggattg tgttattgac gtcaacttat
     3421 ggagaagcag aaggacttgt tagtgatctt atatctatct tgggtgagga actcgtctat
     3481 ccatttttgg tagatgatgc tcctatggtg gagtttttga tgtcttcaca ggaaaaaatt
     3541 atttcacggg ttgaagcctt gcgttttttg actgattcat ctaagaaagg gattttagtt
     3601 tgtaatatcg cagcaagtcg attgatttta ccgtctccca atgcattcaa agatagtatt
     3661 gtaaaaatct cagttggtga agaatatgat caacacgcgt ttatccatca gttaaaggaa
     3721 aatggctatc gaaaagttac tcaagtacaa actcagggcg aatttagtct tcgaggagat
     3781 attttagata tttttgaaat atcccagtta gaaccttgtc gaattgagtt ttttggtgat
     3841 gaaattgatg gtatcaggtc atttgaagta gaaacacaat tatcgaaaga aaataagaca
     3901 gaactcacta tctttccagc tagtgatatg cttttgagag aaaaggatta tcaacgagga
     3961 cagtcagctt tagaaaaaca aatttcaaaa actttatcac ctattttgaa atcataccta
     4021 gaagaaattc tttcaagttt tcaccaaaaa caaagtcatg cagactctcg gaagttttta
     4081 tctttgtgct atgataagac atggactgtc tttgattata ttgaaaaaga tactccaata
     4141 ttctttgatg attatcaaaa attgatgaat cagtatgaag tctttgaaag agacttagcg
     4201 cagtacttta cagaagaatt acagaatagt aaagcatttt ctgatatgca gtatttttct
     4261 gatattgaac aaatctataa aaaacaaagt ccagtgacct ttttctctaa tcttcaaaag
     4321 ggtttaggaa atctcaaatt tgacaaaatt tatcaattca atcaatatcc tatgcaggaa
     4381 tttttcaatc agttttcttt tctaaaagaa gaaattgaac gatataaaaa aatggattac
     4441 accattattc tgcagtctag caattcaatg ggaagtaaaa cattggagga tatgttagag
     4501 gaatatcaga ttaaattgga ttctagagat aagacaaata tctgtaaaga atctgtaaac
     4561 ttaatagagg gtaatctcag acatggtttt cattttgtag atgaaaagat tttattgata
     4621 actgaacatg agatttttca aaagaaatta aagcgtcgtt ttcgaagaca acatgtttca
     4681 aatgcagaga gattaaaaga ttacaatgaa cttgaaaaag gggactatgt tgtccatcat
     4741 atccatggga ttggtcaata tctaggaatt gaaaccattg aaatcaaggg aattcatcgc
     4801 gattatgtca gtgtccaata ccaaaatggt gatcaaattt ctatccccgt ggaacagatt
     4861 catctactgt ccaaatatat ttcaagtgat ggtaaagctc caaaactcaa taaattaaat
     4921 gacggtcatt ttaaaaaggc caagcaaaag gttaagaacc aggtagagga tatagctgat
     4981 gatttaatca aactctactc tgaacgtagt cagttgaagg gttttgcttt ctcagctgat
     5041 gatgatgatc aagatgcctt tgatgatgct ttcccttatg ttgaaacgga tgatcaactt
     5101 cgtagtattg aggaaatcaa aagggatatg caggcttctc agccaatgga tcgactttta
     5161 gttggggatg ttggttttgg aaagactgaa gttgctatgc gtgcagcctt taaagcagtc
     5221 aatgatcaca aacaggttgt cattctagtt ccgacgacgg ttttagcgca acagcactat
     5281 acgaatttta aggaacgatt ccaaaatttt gcagttaatg ttgatgtgtt gagtcgcttt
     5341 agaagtaaaa aagagcagac tgcaacactt gaaaaattga aaaacggtca agtcgatatt
     5401 ttgattggaa cacatcgtgt tttgtcaaaa gatgttgtgt ttgctgattt gggcttgatg
     5461 attattgatg aggaacagcg atttggtgtc aagcataagg aaactttgaa agaactgaag
     5521 aaacaagtgg atgtcctaac cttgaccgct acgccaatcc ctcgtaccct ccatatgtct
     5581 atgctgggaa tcagagattt gtctgttatt gaaactccgc cgactaatcg ctatcctgtt
     5641 cagacctatg ttttggaaaa gaatgatagt gtcattcgtg atgctgtctt gcgtgaaatg
     5701 gagcgtggag gtcaagttta ctatctttac aacaaagttg acacaattgt tcagaaggtt
     5761 tcagaattac aggagttgat tccggaggct tcgattggat atgttcatgg tcgaatgagt
     5821 gaagtccagt tggaaaatac tctattagac tttattgagg gacaatacga tatcttggtg
     5881 acgactacta ttattgagac aggggtggac attccaaatg ctaatacttt atttattgaa
     5941 aatgcggacc atatgggctt gtcaacctta tatcagttaa gaggaagagt cggtcgtagt
     6001 aatcgtattg cttatgctta tctcatgtat cgtccagaaa aatcaatcag tgaagtctct
     6061 gaaaagagat tagaagcgat taaaggattt acagaattgg gctctggctt taagattgca
     6121 atgcgagatc tttcgattcg tggagcagga aatcttttag gaaaatccca gtctggtttc
     6181 attgattctg ttggttttga attgtattcg cagttattag aggaagctat tgctaaacga
     6241 aacggtaatg ctaacgctaa cacaagaacc aaagggaatg ctgagttgat tttgcaaatt
     6301 gatgcctatc ttcctgatac ttatatttct gatcaacgac ataagattga aatttacaag
     6361 aaaattcgtc aaattgacaa ccgtgtcaat tatgaagagt tacaagagga gttgatagac
     6421 cgttttggag aatacccaga tgtagtagcc tatcttttag agattggttt ggtcaaatca
     6481 tacttggaca aggtctttgt tcaacgtgtg gaaagaaaag ataataaaat tacaattcaa
     6541 tttgaaaaag tcactcaacg actgttttta gctcaagatt attttaaagc tttatccgta
     6601 acgaacttaa aagcaggcat cgctgagaat aaggaattaa tggagcttgt atttgatgtt
     6661 caaaataaga aagattatga aattttagaa ggtctgctga tttttggaga aagtttatta
     6721 gagataaaag agtctaagga agaaaattcc atttgatatt tttcttctat aaaatagata
     6781 aaaatggtac aataataaat tgaggtaata aggatgagat tagataaata tttaaaagta
     6841 tcgcgaatta tcaagcgtcg tacagtcgca aaggaagtag cagataaagg tagaatcaag
     6901 gttaatggaa tcttggccaa aagttcaacg gacttgaaag ttaatgacca agttgaaatt
     6961 cgctttggca ataagttgct gcttgtaaaa gtactagaga tgaaagatag tacaaaaaaa
     7021 gaagatgcag caggaatgta tgaaattatc agtgaaacac gggtagaaga aaatgtctaa
     7081 aaatattgta caattgaata attcttttat tcaaaatgaa taccaacgtc gtcgctacct
     7141 gatgaaagaa cgacaaaaac ggaatcgttt tatgggagtg gtattgattt tgattatgct
     7201 attatttatc ttgccaactt ttaatttagc gcagagttat cagcaattac tccaaagacg
     7261 tcagcaatta gcagacttgc aaactcagta tcaaactttg agtgatgaaa aggataagga
     7321 gacagcattt gctaccaagt tgaaagatga agattatgct gctaaatata cacgagcgaa
     7381 gtactattat tctaagtcga gggaaaaagt ttatacgatt cctgacttgc ttcaaaggtg
     7441 ataaaatgga aaatttatta gacgtaatag agcaattttt gagtttgtca gatgaaaagc
     7501 tggaagaatt ggctgataaa aatcaattat tgcgtttaca agaagaaaag gaaaggaaga
     7561 atgcgtaaat tcttaattat tttgttgcta ccaagttttt tgaccatttc aaaagtcgtt
     7621 agcacagaaa aagaagtcgt ctatacttcg aaagaaattt attacctttc acaatctgac
     7681 tttggtattt attttagaga aaaattaagt tctcccatgg tttatggaga ggttcctgtt
     7741 tatgcgaatg aagatttagt agtggaatct gggaaattga ctcccaaaat aagttttcaa
     7801 ataaccgagt ggcgcttaaa taaacaagga attccagtat ttaagctatc aaatcatcaa
     7861 tttatagctg cggacaaacg atttttatat gatcaatcag aggtaactcc aacaataaaa
     7921 aaagtatggt tagaatctga ctttaaactg tacaatagtc cttatgattt aaaagaagtg
     7981 aaatcatcct tatcagctta ttcgcaagta tcaatcgaca agaccatgtt tgtagaagga
     8041 agagaatttc tacatattga tcaggctgga tgggtagcta aagaatcaac ttctgaagaa
     8101 gataatcgga tgagtaaagt tcaagaaatg ttatctgaaa aatatcagaa agattctttc
     8161 tctatttatg ttaagcaact gactactgga aaagaagctg gtatcaatca agatgaaaag
     8221 atgtatgcag ccagcgtttt gaaactctcc tatctctatt atacgcaaga aaaaataaat
     8281 gagggtcttt atcagttaga tacgactgta aaatacgtat ctgcagtcaa tgattttcca
     8341 ggttcttata aaccagaggg aagtggtagt cttcctaaaa aagaagataa taaagaatat
     8401 tctttaaagg atttaattac gaaagtatca aaagaatctg ataatgtagc tcataatcta
     8461 ttgggatatt acatttcaaa ccaatctgat gccacattca aatccaaaat gtctgccatt
     8521 atgggagatg attgggatcc aaaagaaaaa ttgatttctt ctaagatggc cgggaagttt
     8581 atggaagcta tttataatca aaatggattt gtgctagagt ctttgactaa aacagatttt
     8641 gatagtcagc gaattgccaa aggtgtttct gttaaagtag ctcataaaat tggagatgcg
     8701 gatgaattta agcatgatac gggtgttgtc tatgcagatt ctccatttat tctttctatt
     8761 ttcactaaga attctgatta tgatacgatt tctaagatag ccaaggatgt ttatgaggtt
     8821 ctaaaatgag ggaacaagat tttttaaatc attttctcaa gaagggatat ttcaaaaagc
     8881 atgctaaggc ggttctagct ctttctggtg gattagattc tatgtttcta tttaaggtat
     8941 tgtctactta tcaaaaagag ttagagattg aattgattct ggctcatgtg aatcataagc
     9001 agagaattga atcagattgg gaagaaaagg aattaaggaa gttggctgct gaagcagaac
     9061 ttcctattta tatcagcaat ttttcaggag aattttcaga agcgcgtgca cgaaattttc
     9121 gttatgattt ttttcaagag gtcatgaaaa agacaggtgc gacagcttta gtcactgccc
     9181 accatgctga tgatcaggtg gaaacgattt tgatgcgctt gattcgagga actcgcttgc
     9241 gctatctatc aggaattaag gagaagcaag tagtcggaga gatagaaatc attcgtccct
     9301 tcttgcattt tcagaaaaaa gactttccat caatttttca ctttgaagat acatcaaatc
     9361 aggagaatca ttattttcga aatcgtattc gaaactctta cttaccagaa ttggaaaaag
     9421 aaaatcctcg atttagggat gcaatcttag gcatcggcaa tgaaatttta gattatgatt
     9481 tggcaatagc tgaattatct aacaatattg atgtggaaaa tttacagcag ttattttctt
     9541 actctgagtc tacacaaaga gttttacttc aaacttatct gaatcgtttt ccagatttga
     9601 atcttacaaa agctcagttt gctgaagttc agcagatttt aaaatctaaa agccagtatc
     9661 gtcatccgat taaaaatggc tatgaattga taaaagagta ccaacagttt cagatttgta
     9721 aaatcagtcc gcaggctgat gaaaaggaag atgaacttgt gttacactat caaaatcagg
     9781 tagcttatca aggatattta ttttcttttg gacttccatt agaaggtgaa ttaattcaac
     9841 aaatacctgt ttcacgtgaa acatccatac acattcgtca tcgaaaaaca ggagatgttt
     9901 tgattcaaaa tgggcataga aaaaaactca gacgtttatt tattgatttg aaaatcccta
     9961 tggaaaagag aaactctgct cttattattg agcaatttgg tgaaattgtc tcaattttgg
    10021 gaattgcgac caataatttg agtaaaaaaa cgaaaaatga tataatgaac actgtacttt
    10081 atatagaaaa aatagatagg taaaaaatgt tagaaaacga tattaaaaaa gtcctcgttt
    10141 cacacgatga aattacagaa gcagctaaaa aactaggtgc tcaattaact aaagactatg
    10201 caggaaaaaa tccaatctta gttgggattt taaaaggatc tattcctttt atggctgaat
    10261 tggtcaaaca tattgataca catattgaaa tggacttcat gatggtttct agctaccatg
    10321 gtggaacagc aagtagtggt gttatcaata ttaaacaaga tgtgactcaa gatatcaaag
    10381 gaagacatgt tctatttgta gaagatatca ttgatacagg tcaaactttg aagaatttgc
    10441 gagatatgtt taaagaaaga gaagcagctt ctgttaaaat tgcaaccttg ttggataaac
    10501 cagaaggacg tgttgtagaa attgaggcag actatacctg ctttactatc ccaaatgagt
    10561 ttgtagtagg ttatggttta gactacaaag aaaattatcg taatcttcct tatattggag
    10621 tattgaaaga ggaagtgtat tcaaattaga aagaataatc tttaatgaaa aaacaaaata
    10681 atggtttaat taaaaatcct tttctatggt tattatttat ctttttcctt gtgacaggat
    10741 tccagtattt ctattctggg aataactcag gaggaagtca gcaaatcaac tatactgagt
    10801 tggtacaaga aattaccgat ggtaatgtaa aagaattaac ttaccaacca aatggtagtg
    10861 ttatcgaagt ttctggtgtc tataaaaatc ctaaaacaag taaagaagga acaggtattc
    10921 agtttttcac gccatctgtt actaaggtag agaaatttac cagcactatt cttcctgcag
    10981 atactaccgt atcagaattg caaaaacttg ctactgacca taaagcagaa gtaactgtta
    11041 agcatgaaag ttcaagtggt atatggatta atctactcgt atccattgtg ccatttggaa
    11101 ttctattctt cttcctattc tctatgatgg gaaatatggg aggaggcaat ggccgtaatc
    11161 caatgagttt tggacgtagt aaggctaaag cagcaaataa agaagatatt aaagtaagat
    11221 tttcagatgt tgctggagct gaggaagaaa aacaagaact agttgaagtt gttgagttct
    11281 taaaagatcc aaaacgattc acaaaacttg gagcccgtat tccagcaggt gttcttttgg
    11341 agggacctcc ggggacaggt aagactttgc ttgctaaggc agtcgctgga gaagcaggtg
    11401 ttccattctt tagtatctca ggttctgact ttgtagaaat gtttgtcgga gttggagcta
    11461 gtcgtgttcg ctctcttttt gaggatgcca aaaaagcagc accagctatc atctttatcg
    11521 atgaaattga tgctgttgga cgtcaacgtg gagttggtct cggcggaggt aatgacgaac
    11581 gtgaacaaac cttgaaccaa cttttgattg agatggatgg ttttgaggga aatgaaggga
    11641 ttatcgtcat cgctgcgaca aaccgttcag atgtacttga tcctgccctt ttgcgtccag
    11701 gacgttttga tagaaaagta ttggttggcc gtcctgatgt taaaggtcgt gaagcaatct
    11761 tgaaagttca cgctaagaac aagcctttag cagaagatgt tgatttgaaa ttagtggctc
    11821 aacaaactcc aggctttgtt ggtgctgatt tagagaatgt cttgaatgaa gcagctttag
    11881 ttgctgctcg tcgcaataaa tcgataattg atgcttcaga tattgatgaa gcagaagata
    11941 gagttattgc tggaccttct aagaaagata agacagtttc acaaaaagaa cgagaattgg
    12001 ttgcttacca tgaggcagga cataccattg ttggtctagt cttgtcgaat gctcgcgttg
    12061 tccataaggt tacaattgta ccacgcggcc gtgcaggcgg atacatgatt gcacttccta
    12121 aagaggatca aatgcttcta tctaaagaag atatgaaaga gcaattggct ggcttaatgg
    12181 gtggacgtgt agctgaagaa attatcttta atgtccaaac tacaggagct tcaaacgact
    12241 ttgaacaagc gacacaaatg gcacgtgcaa tggttacaga gtacggtatg agtgaaaaac
    12301 ttggcccagt acaatatgaa ggaaaccatg ctatgtttgg tgcacagaat cctcaaaaat
    12361 caatttcaga acaaacagct tatgaaattg atgaagaggt tcgttcatta ttaaatgagg
    12421 cacgaaataa agctgctgaa attattcagt caaatcgtga aactcacaag ttaattgcag
    12481 aagcattatt gaaatacgaa acattggata gtacacaaat taaagctctt tacgaaacag
    12541 gaaagatgcc tgaagcagta gaagaggaat ctcatgcact atcctatgat gaagtaaagt
    12601 caaaaatgaa tgacgaaa
//
LOCUS       DAVKUR010000053        12431 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKUR010000053 DAVKUR010000000
VERSION     DAVKUR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.053"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            121..900
                     /locus_tag="VW749_001725"
     CDS             121..900
                     /locus_tag="VW749_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175727.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            902..1084
                     /locus_tag="VW749_001726"
     CDS             902..1084
                     /locus_tag="VW749_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175728.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(1425..1502)
                     /locus_tag="VW749_001727"
                     /pseudo
     CDS             complement(1425..1502)
                     /locus_tag="VW749_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            1533..1766
                     /locus_tag="VW749_001728"
     CDS             1533..1766
                     /locus_tag="VW749_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0175729.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            1766..3100
                     /locus_tag="VW749_001729"
     CDS             1766..3100
                     /locus_tag="VW749_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0175730.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            3110..3364
                     /locus_tag="VW749_001730"
     CDS             3110..3364
                     /locus_tag="VW749_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0175731.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            3460..3855
                     /locus_tag="VW749_001731"
     CDS             3460..3855
                     /locus_tag="VW749_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0175732.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQPAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            4267..4715
                     /locus_tag="VW749_001732"
                     /pseudo
     CDS             4267..4715
                     /locus_tag="VW749_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            4702..5262
                     /locus_tag="VW749_001733"
     CDS             4702..5262
                     /locus_tag="VW749_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175733.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHIFPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLDFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            5262..5840
                     /locus_tag="VW749_001734"
     CDS             5262..5840
                     /locus_tag="VW749_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0175734.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAEILQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            5833..8484
                     /locus_tag="VW749_001735"
     CDS             5833..8484
                     /locus_tag="VW749_001735"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0175735.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVIAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            8565..8729
                     /locus_tag="VW749_001736"
     CDS             8565..8729
                     /locus_tag="VW749_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0175736.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            8780..10384
                     /locus_tag="VW749_001737"
     CDS             8780..10384
                     /locus_tag="VW749_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0175737.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFLRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWFDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            10764..11567
                     /locus_tag="VW749_001738"
     CDS             10764..11567
                     /locus_tag="VW749_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0175738.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(11683..12431)
                     /locus_tag="VW749_001739"
                     /pseudo
     CDS             complement(11683..12431)
                     /locus_tag="VW749_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3829 a         2239 c         2664 g         3699 t
ORIGIN      
        1 tgtttcattt tactataaaa aaaggggttc tgtatttttt aatgttatct aattagaaaa
       61 tgcttttttt gtaggaaata taatatgata aggtgtaaaa aagaaataag gagtttgtat
      121 atggctgaac aagacttagc tatgcaagta ttacaacaag tggtaaaact accagttgtt
      181 aaggttgatc gttcgaaatt tttagtggat aagttttcca aagaattggg tccacaggac
      241 attcctacct tattggaaca aggtccaacg tctctcttat ctcaagaaat cttagatcga
      301 gtggctaatg cctgtattag ggataatgtt ttattagcga gtgggacttc tgttttggca
      361 ggattacctg gagggcttgc tatggcaatt accattccag ctgatgtggc tcaattttat
      421 gctttctctc tgaaattggc ccaagaatta ggttatattt atggttatga ggatctttgg
      481 gcttcacgcg atgagttgag tgaagatgct caaaataccc tcttgcttta tctaggcgtc
      541 atgttggggg tgaatggaac tgctgctttg ctacgtgctg gtggtataac aattgccaaa
      601 caggtaatga aaacagtacc taataaagct ttaactaaga cgctttggta tcctattttg
      661 aaaaaagtct taagaatatt tggtgtgaat cttaccaagg gagggctggc caaaggaatg
      721 gggaaattta ttcctatctt gggtggtatc atttcaggtg gtttaacctt tgcaactatg
      781 aaaccgatgg gtgaaagctt gcagaaagaa ttgtccaagc tagttaacta tagtgaagtt
      841 caatatcaag aagatgttga aacaatccga aaagaggctg aaatcatcga aggagagtaa
      901 tatgggactc ataaaaactc tagctaaaat ttatggtaat tactttttga ccgtgcaagg
      961 tgtaaaagtg atgaaaacga taaagaaagc tgaccatgtc gttgttggtc tgggcaaact
     1021 ttttattgca gataagctaa tggatacggc tcggtggctc attaagccag aggagagaga
     1081 atgaaatttt tttggtcttc ttgctattct ttttatcaaa ccgattattg ggattgtgaa
     1141 attcttttgg atgatcattt cttttgcagt tcaattgctg ttttacaaga tattggattg
     1201 gttctttaaa cttatctaga tggtaatcca agtcgcagaa aactagcagg aaccccactg
     1261 ctagtttttt aatctctctc catatggtat aatataagca gtaaaatcat tttatactct
     1321 tcgaaaatct cttcaaacca cgtcagcttc accttgctgt aggtatggtt actgacttcg
     1381 tcagttctat ctacaacctc aaaacggtgt tttgagctga cttcgtcagt tctatccaca
     1441 acctcaaagc actgttttga gcagtctgca gctagcttcc tagtttgctc tttgattttc
     1501 attgagtatt agaacataca atggaggtcg tcatggacaa tatcatcgat gtgtcaattc
     1561 ctgttgcaga agtggtggac aagcatccag aagtcttgga aattctagtg gagttgggtt
     1621 ttaaacccct tgccaatccc ttaatgcgca atacagttgg tcgcaaggta tcgctcaaac
     1681 agggttctaa gctagcagga actcctatgg acaagattgt acgcacactg gaagcgaatg
     1741 gctacgaagt gattggatta gactaatggc agatgaacgg attcatgtcc tacgggatat
     1801 tttgttagaa ttgcacaatg gcgcctctcc tgagtcggtt caagagcgct ttgatgcgac
     1861 ctttgcgggt gtctcagcca tcgagatttc ccttatggag cacgagctga tgaactcaga
     1921 ctcaggtgtc acctttgaag atgttatgga actctgtgat gtccatgcca atctttttaa
     1981 aaatgctatc aaaggtgtcg aagtttcaga tactgagcat ccaggtcacc cagttcgtgt
     2041 cttcaaagaa gaaaatctgg ctctccgtgc ggccttgatt cgcattcgta gattgttaga
     2101 tacctatgag tatatggaag acgaggaaat gctggcggag atgcgtaagg gtttggtgcg
     2161 tcagatggga cttgtgggtc aatttgacat ccattaccaa cgtaaggaag aactcttctt
     2221 tcctatcatg gagcgctatg gacacgattc acctcccaaa gttatgtggg gagtggatga
     2281 tcagattagg gaactctttc aaacagctct aacgacagcc aagtcactac cagaagtgtc
     2341 aattagcagt gtaaaggaag cttttgaagc ttttgcgaca gagtttgaaa gtatgatttt
     2401 caaggaagag tccatcctcc tcatgattct ccttgagtct tttactcagg atgactggct
     2461 tcagattgcg gaggagagcg atgcctatgg ctatgccatc atccgtccgt cagagaaatg
     2521 ggtgccagaa cgacagagct ttattgagga aaagattgca gaggagcctg tacagctaga
     2581 tacggcagaa ggtcaagttc aacaagtcat agatacgcca gaaggccatt ttaccattac
     2641 ctttacccct aaggaaaagg aagctgtgct ggaccgccat agtcaacagg cttttggtaa
     2701 tggctatctt tcagtcgagc aggccaatct catcctcaat cacctcccta tggagattac
     2761 ctttgtcaat aaagatgata ttttccagta ttacaatgac aatacgccag ctgatgagat
     2821 gattttcaaa cggacgccgt ctcaagtcgg gcgcaatgtc gaactctgcc atccgcctaa
     2881 gtacttggac aaggtcaaaa ctatcatgaa ggggcttcgt gagggaagca aagacaagta
     2941 tgaaatgtgg ttcaagtctg agtcgcgagg taagtttgtc cacatcacct atgctgcagt
     3001 acacgatgaa gacggagaat tccaaggagt gttggagtat gttcaggata tccagcccta
     3061 ccgtgagatt gatacggact attttcgtgg attagaataa ggagaaaaaa tgagttacga
     3121 acaagaattt atgaaggaat ttgaagcttg ggtcaatacc caaatcatga ttaacgacat
     3181 ggcgcacaag gaaagtcaaa aagtttacga agaagaccag gacgagcgtg ccaaagatgc
     3241 catgattcgc tacgagagtc gcttggatgc ttatcagttc ttgcttggta agtttgaaaa
     3301 cttcaaagca ggcaagggat tccatgattt gccagaaggc ttgtttggtg agcgaaatta
     3361 ttaaacgaga aagattcttg atttttcact aaaatcttga tagaatgttt atgttaaatc
     3421 cttgtcagag cagggatttt ttattgaaag gattttatca tgtcaaagaa actcaatcgt
     3481 aaaaaacaat tacgaaatgg cctccgtcgc gcaggtgcct tttcaagtac tgtgactaag
     3541 gttgtagatg agacaaaaaa agtcgtgaag cgtgcagaac agccagcaag cgcagctggt
     3601 aaggctgttt ctaaaaaagt tgaacaagca gtagaagcta ccaaagagca agctcaaaaa
     3661 gtagctaatt ctgtagaaga ttttgcagca aacttggggg gacttccact tgatcgtgcc
     3721 aagactttct atgatgaagg aatcaagtct gcttcagatt tcaaaaactg gactgaaaaa
     3781 gaactccttg ccttgaaagg aatcggccca gctaccatca agaaattgaa agaaaatggc
     3841 atcaagttca agtaattttt cttgagcctt gcatttccga gaaaaacttg ctacaataga
     3901 gccattagag gtgttttgaa tcccacattt tacagaaagt ggcggcgctg agaagtccac
     3961 aaatgtgtca aaactggttg ctaatgactg aaaaaatgaa atatttctgt ctttttattt
     4021 taaagactaa agatgcgggc ttggcccgaa attgggtggt accgcggata aacacattcg
     4081 tccctgtcat gtagatggca gggcttttct tttgtgtctt agtcaaagga ggttgttata
     4141 aaacaatcat ttaaaactaa taaactatat tatggttttc ctgtttttat tttaggatat
     4201 caagatcaga attttagcta taacatcatg acctgtagtt cctcttatag tctaggagat
     4261 tgggttgtga ttggagtcgt tgcgagagag aatgccgcag agcagatcaa acaatatcaa
     4321 aaatttactg tgaatatttc tgatgaaact tctatgcttg cgatggagca ggctggtttt
     4381 atcagtcatc aggagaaatt ggaacgtttg ggagtgcatt atgaaatttc tgaacgaact
     4441 cagactccta ttttagacgc ctgtccactt gttttagatt atcgggtaga taggattgtt
     4501 gaggaatacg gtatttgcca catctttgcc aagattcttg agcgacttgt tgccccagaa
     4561 ctcctggatg aaaagggaca ttttaaaaat caactgtttg cccaacctat ttcatgggag
     4621 atggatatca gcgcgtttat tgctatctgg acaagcgtgt agatatgaag ggcagtttca
     4681 tcaaaaaagc gaggaagaag gatggcaaga actgagctgc cagataaaat cgaaacagaa
     4741 cgtctcgttt tacgagtccg tactgtggcg gatgctgagg atatctttga ctatgctagt
     4801 ttgccagagg tcgcctatcc agcaggtttt cctccagtca agaccttgga agatgagatt
     4861 tattatctgg agcacatttt tccggagcgt aatcaaaagg aaaatctccc agcaggctac
     4921 gggattgtcg tcaaaggaac ggataagatc gttggctctg tcgatttcaa ccatcgccat
     4981 gaagatgatg tgctggaaat cggctatacc ttacacccag actattgggg gcgaggttat
     5041 gtgccagaag ctgcgcgtgc cttgattgac ttagccttta aagatttggg tcttcacaag
     5101 attgaactaa cttgctttgg atataacctt caaagtaaac gagtcgcgga aaagcttgac
     5161 tttaccctcg aagctcgcat aagagaccgc aaagatgctc aaggcaactg ctgtgatgat
     5221 ttaagatatg ccttgctgaa gagtgaatgg gaggtgattt gatgcatctt ttcatcattg
     5281 gtgctccagc atcaggaaaa atgaccattg gtcaagaatt atctcgactg acggatgcta
     5341 ccctatttta taaccatcaa gccatcgatt ttgcactaga aatctatcag gactatacag
     5401 aggaaatgtg ggaatttgtt cgtggaatca ctttttcatt ccttggagcg agtgcaagaa
     5461 atcagcgatc agtaatttta acagatgtaa ttgatttttc aaatcagtat catctgatat
     5521 atttaaagca aattcagagt ttgttggatg attatcatca agagattctt tttgttgagt
     5581 tggaaacaag tcttgaagag tgcatacgtc gaaatcgaac ggagaatcga ttaaagtaca
     5641 aacccttaaa acgacatatt gaggtatctg aaagagaaat tatagagacc gctgaaatac
     5701 ttcaattaaa ttcccaatat caaccgaatg agttgcacca ctactttaaa ataaataata
     5761 cgaatttgtc tgcagaagaa gctgctaagc aaattcaaaa taaaataaac aaaatagaga
     5821 aaggacacac acatgtctaa agaactttca tctaaataca atccagccga ggttgaggct
     5881 ggtcgttacc aaaaatggct tgatgctgat gttttcaagc cttcaggcga tcaaaaggct
     5941 aagccttatt caatcgttat tccaccacca aacgttacag gtaaacttca ccttggtcac
     6001 gcttgggata caactttgca agatattatc atccgtcaaa aacgcatgca aggttttgat
     6061 acgctttggc ttccaggaat ggaccacgct ggtattgcga ctcaggctaa ggttgaggag
     6121 cgcttgcgtg gtgagggcat ttcccgctat gaccttggtc gtgagtcttt cttgacgaaa
     6181 gtctgggaat ggaaagacga atatgccact accatcaagg aacaatgggg caagatgggg
     6241 ctctctgtag actattctcg tgagcgtttc actcttgacg aaggtttgtc aaaagctgtt
     6301 cgtaaggtct ttgtggacct ttacaagaaa ggctggatct accgtggtga gtttatcatc
     6361 aactgggacc cagcagctcg cacagccctt tctgatattg aggtgattca caaggatgtg
     6421 gaaggtgcct tctaccacat gaattacatg ctggaagatg gttcacgcgc ccttgaagtt
     6481 gctacaactc gtcctgagac tatgtttggg gacgttgcgg ttgcggttaa tccagaagac
     6541 ccgcgctaca aggacttgat tggtaaaaac gtcatccttc caatcgctaa taaactcatc
     6601 ccaatcgttg gagatgagca cgcagatcct gagtttggta ctggtgtcgt gaaaatcaca
     6661 cctgcccacg atccaaatga cttcttggtt ggccaacgtc ataacttgcc acaagtcaac
     6721 gtcatgaacg acgacggaac tatgaatgag cttgcctttg aattttcagg catggatcgt
     6781 tttgaagctc gtaaggcagt cattgctaag ttggaagaaa tcggtgccct tgtcaaaatc
     6841 gaaaaacgtg tccacagtgt tggtcactca gaacgtacag gtgtcgtagt tgagccacgc
     6901 ttgtctactc aatggttcgt caagatggac caattggcta agaacgccat tgccaaccaa
     6961 gacacagagg acaaggtcga attctaccca cctcgtttca acgatacctt ccttcaatgg
     7021 atggaaaatg tccacgactg ggttatctct cgtcagcttt ggtggggtca ccaaatccct
     7081 gcctggtaca atgctgatgg tgaaatgtat gtcggcgaag aagctccaga aggtgacgga
     7141 tggactcagg acgaagacgt cttggatact tggttcagtt ctgccctctg gccattttca
     7201 accatgggct ggcctgaagt cgactcagaa gactttaaac gttatttccc aacttcaacc
     7261 ttggtaacag gttacgacat catcttcttc tgggtgtctc gtatgatctt ccagtcattg
     7321 gaattcacag gccgtcaacc attccaaaac gtccttatcc acggtctcat tcgtgacgag
     7381 caaggacgca agatgtctaa gtctctcggt aacgggattg acccaatgga tgttatcgag
     7441 aaatacggtg ccgatgccct tcgatggttc ctttcaaacg gttctgcgcc aggacaagac
     7501 gtgcgtttct cttatgagaa aatggatgct tcatggaact ttattaacaa gatttggaac
     7561 atttctcgct atatcctcat gaacaatgga ggtttgacgc tggatgtggc gcatgacaat
     7621 gtcacaaaag ttgcaacagg tgaggctggt aatgtgacgg accgctggat tctccacaat
     7681 ctcaacgaaa ccattgcaaa agttactgaa aactttgata agttcgagtt tggtgtggct
     7741 ggtcatatcc tttacaactt catttgggaa gaatttgcca actggtatgt tgagttgacc
     7801 aaggaagttc tttacagcga caatgaagac gataaggtaa ttactcgatc tgttctcctc
     7861 tatacgctgg ataaaatcct tcgtctcctt cactcaataa tgccgttcgt gacagaagaa
     7921 atctttggtc agtacgctga aggctctatc gtgacagcag catacccaac tgtcaaccca
     7981 gcctttgagg accttgctgc ccacactggt gtggaaagtc tcaaagactt gatccgtgcc
     8041 gttcgtaatg cgcgtgcgga agtaaatgta gcaccaagca aacctatcac catccttgtt
     8101 aagacaagcg atagcgactt ggaagccttc tttaacagca atgtcaacta tatcaaacgc
     8161 tttacaaatc cagaacactt ggaaatcgca tcaaccatcc ctgcacctga actggctatg
     8221 tcaagcgtta ttacaggagc cgaaatcttc ttgccactgg tagacctctt gaatgtcgaa
     8281 gaagaattgg cacgtctgga aaaagaactt gccaaatggc agaaagaact cgacatggtt
     8341 ggcaaaaaac tcagcaacga acgcttcgtc gccaacgcta aaccagaagt tgtccaaaaa
     8401 gaaaaagaca aacaagccga ctaccaagcc aagtatgatg cgaccgtagc acgtattgat
     8461 gagatgaaga agttggtgaa atgatgttaa aaacctaacc ctatcgggtt gggttttaca
     8521 tttgataatg ttataataaa aaggagaaac tttaggagaa tactatgggg aaaattgttg
     8581 ctattgattt atttaacggt gcaggtggca ctacaagtgg ccttaaaaaa tcaggcatag
     8641 atgttcaagt tgctgttgaa attgattccg tagctgttaa aacttataag ttaaataatc
     8701 ctgaggtgtc tgtaatagat atggagtaaa taaaacttca attttacaag ctttatatgg
     8761 ttctccagcc aataaaagtg tgtctgaata ttggtttagt acaaatgttg atcaaataga
     8821 tgaagtggat gggaaacaat gtttaatcta ttcatattat aacgttaaag cttctagaaa
     8881 tgtagaagtt cttaaaggcc gttctggaac aaaaaaagga ttagattatt gggaaccata
     8941 tgctcctcaa aaacaatatg agatggaaag attacccaaa aataaatata ttggaagttc
     9001 ttcgacagac agatgggatg gcattgaaaa aaatgttgtc ttttgtgatt gtaaagaata
     9061 tgtttctgct tttgatttat ttttctatca ctataatttt aaaaaaattt ctactcaacg
     9121 tagtaaacaa gattttataa gattacgatc taaaccagtt gctgatattt taaagaataa
     9181 tacaagtagt tatacgcgtt ataaaaagga aatggttata gataatgtta aagttgatga
     9241 taaagtttgt gaaattatta gtgaaataat ggatgaatct tatacagaca ttcaaatttt
     9301 aacacataag ttgtattcaa aaggtgatga tataaaagct tccaaaacta tttggatgaa
     9361 aaaatctgga aaagaatatt ccgaggcttt tgcaggaaca ggtgaggcta gaattatttt
     9421 gttagtaaat gatatagtaa atgcgcaatc aaattcatta atattaatag atgaacctga
     9481 aatctcactt catccgagtg caatctataa atttaaagag tttttacttc aagagtgttt
     9541 aaataaaaaa catcaaatta ttatcactac acattctaca caacttataa aagattttct
     9601 tagagaagcc gtgaaacttt tagtgaaaaa cggagaaaag gtagatgtta ttgaaaatat
     9661 tgattatcag gatgcatttt ttgaattagg tgatgtgtat cattctagga agatgattta
     9721 tgttgaagat agactagcta aatatattct agagtttgtt atcactcatt caggtagtga
     9781 gaatcttaaa cagaatttag tagtgagata tattcctggt ggagcaaatc aaataatttg
     9841 taataatatt ttaaactcat cgtatttaga ttccgataac cattattttt ggtttgatgg
     9901 agatcaaaac actaatgtta gtgaatcaaa taatttaatg aactatcttg aaaatggtgt
     9961 tgttatatca gataaaattc ctgaatcaga taataaaaat cttgatgata ttataaaatt
    10021 gataacggga tgtccaatta aatttaatgt ttcaggtaat aaagggcaaa aaaataatat
    10081 tgaattaatt gcgaaacaaa gaagctttat agattattgg gctaaatacg tttcttatct
    10141 tcctttccca accccagagt tttttttagc taatttgtgt aacagcgtag atagggaagg
    10201 ttatgatttt tctaaagatg gcaacggaaa agaatatttt agaaaaaaaa ctcaagtagc
    10261 gttaggaata gagaatataa cttctgaaga tattttccag gagcaaagaa gagctgtttc
    10321 aaaaatacag ccagaatcat caatgtttca gtgtattaaa gaaaaattag aggcattgtt
    10381 ctaattcctt agattaggta ctacataaca aattttttaa attcaaaccc gcaccaaaaa
    10441 caacattgca actttcttct caggtaatgt gttgggattt gaacagacca acgagttcat
    10501 agaggtgtat gccaatgagt ttgataagta tgcgcgtcag acttattagt tcatttatcc
    10561 agatatatct cgataatcat attatttagt caaagaacat cccatatgag ggcatgaaat
    10621 gctaagttta gcttgctcac tattaagatg aagtatatat atttcataga acttattgtg
    10681 aaggattttt ataattttcg ccaattccat acccatttca ccatttaccg atgacacaga
    10741 aaaacaattg aaaggatatt tctatgcaac caacttacaa cattgacaat ccaaacttgt
    10801 cttatgaagc gaagcgtgat ttatggcgga taggttttgg tctgcagaaa gttgacaatc
    10861 tagtgccatc agcgtatatg gaatctttgg ctgagaaaca gtcccgggga gaactgactt
    10921 atgagcaggt ttatgaggat gcaacggctt atcaccatac tattgatgca agtacggaag
    10981 aggcagactt ggtttctcta cgtattgtag aactattgtc tcgaagaggc tttagcttta
    11041 gtcctgcgac cttacttgct attcataagg agttgtttca agatatattt gaaccctcta
    11101 ttccggtggg gcaatttcgt cagaccaata tcacaaagaa tgaacctgtt ttgaatggtg
    11161 aaagtgttgt gtactctgat tactccatga ttcaaatgac cttagattat gattttaatc
    11221 aggaaaaaca agttgcatat gcgacactaa ctcaggcgga tgtggttaaa caaatccagc
    11281 attttatttc aggaatctgg cagattcatc catttcgcga aggaaacact cggacagtaa
    11341 cggtcttttt gattcagtat cttcgtgagt ttggttttga tattgataat acaccatttc
    11401 agcaacattc caaatatttt cgtgatgcct tggtattaga taatgcaaag attttacagc
    11461 gacgtcctga gtttttaaca gctttttttg aaaatctctt gctcggtggt caaaatgatt
    11521 tgtcttcaga aaaaatgtat ctagatttag accttgattt ttcataatcc aaatactgag
    11581 taaacattga attttaggca aaaatgaagt aaatattctc acaagaaaac gtatatcatc
    11641 aaagttttag gtgtactgac cccaaacagt tagacaatta atttatccga aggatttagt
    11701 tctgtattgc acaggactaa gtccttttag ttttacctta attcgtttat tgttgtagta
    11761 atcaatatag tctacaatag cttgttccaa ttgcttaagc gactgaaacg acttctcata
    11821 accgtaaaac atttccgatt tcagaatccc aaagaaagat tccatcatac cgttgtcttg
    11881 gctgtttccc ttgcgtgaca tggatgcttg aactccctta ctctctagga accgatgata
    11941 agaatcgtgt cggtattgcc agccttggtc actatggaga atcgtattct catagtgctt
    12001 ctctgtgaat gcctgttcca acattgtttg tacttgttct aagttgggtg aagttgaaag
    12061 attataggcg ataatttcgc tattaaagcc atctaaaact ggtgataagt aaagcttttg
    12121 agtacttgct ggaatggcaa attctgtcac atctgtgtag cactgttcca ttgttttaga
    12181 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttatgaga
    12241 agaatatttt cgtttctgtc gcattttagc ttgtaaattg agtacttcat caagtgttga
    12301 actcttttat gatttaccag ataaccacga tttcttagtt ctaaataaat ccgacgataa
    12361 ccataatttc ccttgtgttc gataaagatg gattgaattt cagctttaag ctcttggtcc
    12421 ttatctgttt t
//
LOCUS       DAVKUR010000054        12279 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKUR010000054 DAVKUR010000000
VERSION     DAVKUR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.054"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            75..329
                     /gene="blpM"
                     /locus_tag="VW749_001740"
     CDS             75..329
                     /gene="blpM"
                     /locus_tag="VW749_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0175739.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            345..548
                     /gene="blpN"
                     /locus_tag="VW749_001741"
     CDS             345..548
                     /gene="blpN"
                     /locus_tag="VW749_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0175740.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            792..941
                     /gene="blpO"
                     /locus_tag="VW749_001742"
     CDS             792..941
                     /gene="blpO"
                     /locus_tag="VW749_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0175741.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1045..1164
                     /locus_tag="VW749_001743"
     CDS             1045..1164
                     /locus_tag="VW749_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0175742.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1633..2004
                     /locus_tag="VW749_001744"
     CDS             1633..2004
                     /locus_tag="VW749_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175743.1"
                     /translation="MIKKNHILCEIVPGAVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            2633..3016
                     /locus_tag="VW749_001745"
     CDS             2633..3016
                     /locus_tag="VW749_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0175744.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3068..3757
                     /locus_tag="VW749_001746"
     CDS             3068..3757
                     /locus_tag="VW749_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175745.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3799..4032
                     /locus_tag="VW749_001747"
     CDS             3799..4032
                     /locus_tag="VW749_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175746.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4183..4794
                     /locus_tag="VW749_001748"
     CDS             4183..4794
                     /locus_tag="VW749_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175747.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4955..5749
                     /locus_tag="VW749_001749"
     CDS             4955..5749
                     /locus_tag="VW749_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0175748.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5746..6381
                     /gene="trmB"
                     /locus_tag="VW749_001750"
     CDS             5746..6381
                     /gene="trmB"
                     /locus_tag="VW749_001750"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0175749.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQDPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6507..6986
                     /gene="rimP"
                     /locus_tag="VW749_001751"
     CDS             6507..6986
                     /gene="rimP"
                     /locus_tag="VW749_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0175750.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMGKTRKKTVQIPYSLVSKARLAVKL"
     gene            7030..8166
                     /gene="nusA"
                     /locus_tag="VW749_001752"
     CDS             7030..8166
                     /gene="nusA"
                     /locus_tag="VW749_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0175751.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8188..8481
                     /locus_tag="VW749_001753"
     CDS             8188..8481
                     /locus_tag="VW749_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0175752.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8474..8773
                     /locus_tag="VW749_001754"
     CDS             8474..8773
                     /locus_tag="VW749_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0175753.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8790..11582
                     /gene="infB"
                     /locus_tag="VW749_001755"
     CDS             8790..11582
                     /gene="infB"
                     /locus_tag="VW749_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0175754.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11833..12183
                     /gene="rbfA"
                     /locus_tag="VW749_001756"
     CDS             11833..12183
                     /gene="rbfA"
                     /locus_tag="VW749_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0175755.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3757 a         2119 c         2762 g         3641 t
ORIGIN      
        1 taaaaaacga tgatatacta aacttgtcaa agttacaaca agacaaaaat taaaaataaa
       61 aaagagtatt tgtcatgaat acaaaaatga tggaacaatt tcatgaaatg gatataacta
      121 tgttatctag tattgaagga ggcaagaata attggcaaac taatgtctta gaaggtggtg
      181 gtgctgcttt tggtggctgg gggctaggga cagctatttg tgctgcgagt ggtgttggag
      241 caccatttat gggagcatgt ggatacatag gagctaaatt tggtgtggat ctttgggcag
      301 gagtaacagg ggcaacgggt ggattttaat aaaaggagac ttgtatgaat acttattgta
      361 atataaatga aacaatgctg agtgaggttt atggaggtaa ttccggagga gcagctgtag
      421 ttgctgcttt aggttgtgca gcgggtggag tgaaatatgg gaaaattcta ggaccatggg
      481 gcgctgcaat aggaggaatt ggaggagcag tggtttgtgg atatttagcc tataccgcta
      541 catcataaaa atgaaagcta aattttatga aggctatatt ctttattatt ctcttcgctt
      601 ttcaaaccta tcttatttat ctatccataa gtatctctga taaaaaacaa aagactattg
      661 aattaacatc attgaattgt tttgtcatat tatttctaat ctatgataaa ttaatttttc
      721 tctttattgc ctatgttttt ttgataattt ttatattaaa cttgttccgt aactgaaaag
      781 tgacatacta tatgaataca aaaatgatgt cacaattttc tgttatggat aatgaaatgc
      841 ttgcttgcgt tgaaggtgga gatattgatt ggggaagaaa aattagttgt gcagcagggg
      901 ttgcatatgg cgcaattgat gggtgtgcaa caacggtttg acatttctat tgggaccatt
      961 tgctatagga ataggtgtaa ctggtgctgc aggtggagct atacttggag gtgtagccta
     1021 tgtagcaaca tgttggtggt aattatggat tttaaaagtt ttattattgg tttagtagtt
     1081 ggtatatttg gtccttatat ggatgactta attagaaaaa tattttcaaa atcttccaaa
     1141 aaggatacgg atagtactct ctaaaaaata aatttctccc ctgtatttgc tagcttaatt
     1201 tacaggggag tttctttaat attgtttcgc ctgtcaaaat gatatgtgat agcaggatga
     1261 aaagtctaca aacaagttgg tatcaataca acataaagag gaaagtatgt ttttcatgct
     1321 tgcttttttt aatttttaca attcaagagg ttttgatgac catttatgat ttgagtgatc
     1381 caaggtcaaa ataagtgcta tactagcagt gtaaatgttc ttgctcaact aagataaatc
     1441 gcacatttag gaggaaatct tatgaagaaa aaaatactga ttattttcgt tctgtatctg
     1501 atcatgtcca tctttcttta tccgcttagg gagagtattt ggtataatct attttatacc
     1561 atagcctata tgattgcggt tatgatctat ttttctttaa ttaaaaagaa agaaaagaaa
     1621 tgaaagattt tcttgattaa aaagaatcat attctttgtg agattgttcc tggggcagtt
     1681 gcctttgctt gtttctactt atctatttct atttcgtcag ttttccaatt tcttttagtg
     1741 gttattaact tagcttctat tttggtcact gtttacctca ctagggaaat gcggataaaa
     1801 gagtttgaag acgatgattt ggttagtcct agaaccaatc aactcatgtt tatcggcttg
     1861 acaggcttta tgtctattat ttgtttgtat agaggtatca cagcaggaga atcttatcaa
     1921 caactaatcg cttatattgg tgctattctt tgcttgatca tcatgcttct actcatttgg
     1981 ggtttgaagt attataaaaa gtaggggcta atgaagtttt tgcaatttag gaggtttcga
     2041 tgacaattca agatttggat gaaaaatttt aaaaaacaat gatatactaa acttgtcaaa
     2101 gttgcaacgg gtgctgctac attatgttaa aaatcgctct tgattgataa gttggatttg
     2161 ttaggaaagg agtaaataat tatggataag aaaaagatag tttcgactat aatatgtata
     2221 gtatttcttg tagtgtcagt agataatttt tttagagact taaccccgtt attgttcatt
     2281 ttaaatatta ttggcctaac ttgtttttta gtgttaacat acactaacat aaaagagata
     2341 ctcttaaata taagtaaatg atgatttggt tagtcctaga accaatcaac ttatgtttat
     2401 cggcttggca gattttatgt ttgtcatttg tttgtataga ggtatttcag aaacagaatt
     2461 ctatcaacaa ctaatcgctt atataggtgt attctctgct tgtttatcac gcttctgctc
     2521 atgtggggct tgaagtatta taaaaagtag ctttctatcc ttttctgaca ggatatttga
     2581 gtagaaggct ctattaaatt gttagtgaaa taaatgaatg gaggtattta atatgaaata
     2641 cagattattt tttgttattt tcttgagtag tgtgttggat attcttttag ggacattttt
     2701 acaaatctct atcgtatcta ttgggtggct tgttctttac agtggtttgt ttgaagcagg
     2761 agttttcctt cttgctaata aaggggtggc ggtaaaaatc aaggaagtag atattcgaaa
     2821 tcgctttaaa tttatttttg gaaaaacctt atggtttcaa attcttttgc tcatcttttt
     2881 gataatcaaa ctttatcttg gtttggatgc gaggttgatt ttattctatg gacatatttt
     2941 cattgtcttt aatgccttaa tgtatctatt atctagtagt caggttagcc ttaaaaaaaa
     3001 caaactgtct tcttaatctt acagcagtag agcctgacaa ggtgaggtta tagtagggag
     3061 gatttctatg aaaaagtatc aacttctatt caaaataagt gcagtcttct cttacttatt
     3121 tttcgtattt ggtctttctc agctgacgct tatcgtccaa aactattggc aattttcttc
     3181 tcagataggc aatttattct ggattcaaaa tatcttgagt ttacttttta ttggagtcat
     3241 gattgtggtt cttgttaaga caggccatgg ttatctcttc cgcattccaa gaaaaaaatg
     3301 gctttggtat tcgattttga cagtattagt ggtagtgttc cagatctctt ttaacgttca
     3361 gacagctaaa catgttcagt caactgcgga aggttgggct gtattgattg gttatagtgg
     3421 gactaacttt gcagagctag gtatttatat agccctgttc tttctggttc cactgatgga
     3481 agaattgatt tatagaggat tactgcaaca tgctttcttt aagcattcgc gatttggtct
     3541 tgatttgctt cttccttcta ttttatttgc tctccctcat ttttcaagcc tgcctagtct
     3601 gttagatatc ttcgtctttg caacagttgg aatcatcttt gctggtttga cccgctatac
     3661 caagagcatt tatccatcct atgcggtgca tgtgatcaat aatattgtag cgaccttccc
     3721 gtttttgctc acttttctac atagggtctt ggggtaaaaa aacaaaaggc ttgcttttca
     3781 gccatagagg aggtcatcat gtataaacac ttatttttcc tagattccaa aactttagat
     3841 cggttgacac cctatattct agtcttggct tctgacacca ttgcttttaa tgtttttgtg
     3901 ctaacctttg tatctgcggt ggtttttaat ttcctaaatt ccatgctagc tttaatggct
     3961 atattcatag gggctggcta tgtggtcgga ttttggttac taatactcaa tgaaaatcaa
     4021 agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgt
     4081 ggtttgaatt tgattttcga agagtataaa atggtttgtt ttggaaaggc tagaactaaa
     4141 gaatgacgtg taggaagtct gtttgttgag gaggataatt ttatggagtt ttttgataaa
     4201 tttcatgcct tgtgttttgg atttttagta ctaataattg tcattacagt tccttatacg
     4261 attaaccatg ggggtttttt tcaaaatgaa tctgcattga ttcttgtaag tcttcttgta
     4321 acctcgctga gtgttgctta tgctagaaag tttgaaatga tttcttttgg gatgttaagc
     4381 aagaaacaac ttttgctttt cattgcaatc tttcttctaa gtgtacttga gacgctggtt
     4441 tatattcatt tcttcgctgt ttcttctggc tcaggggtcc aacacttggc ggaagtcagc
     4501 agaggaattt ccctgtcttt gattttgact acctcagttt ttggccccat ccaggaggaa
     4561 ctcattttca gaggacttct tcaaggtgcg gtttttgaca attcttggtt agggcttgtg
     4621 ctaacttcct ctctcttttc tttcatgcat ggaccttcta atgtcccttc gtttattttt
     4681 tatctacttg ggggtttgtt gctgggcttt gcttataaaa agagtcaaaa cctatgggtt
     4741 tctactctag tccatatgct ttacaacagt tggccactct tatattattt ataaaaatta
     4801 tgaaaaggta agcagaagac ggtgcttacc tttttcaagc tataatgata cccaagccaa
     4861 tccagaggct tttctttgag aatcgggtta gagtggttga cgaataggcc aaaaactagt
     4921 agaatagtaa ggaaacttta tacggaggaa agaaatggat ttgggtgata atgagctaac
     4981 actgactccc atacctggga aaagtggcaa ggcttatatg ggtagctatc ctgatgggaa
     5041 gcgcatcttt gtaaaaatga acacctctcc aatcctacct ggtctagcta gagaacaaat
     5101 tgctccacaa ttattatgga gtcgtcgttt ggcagatggg cgtgatatgt gtgctcaaga
     5161 atggttgaca ggcaagatat tgacccccta tgatatgaat cgtaagcaaa tcgtcaatat
     5221 tttaacccgt cttcatcgct cacgtccgtt gatgacacaa ttgagtcgtt tgggctatgc
     5281 catggaaaca cctgtagatt tactacagtc ttggcaggaa acggctccag atgctttgcg
     5341 taaaaatcat tttatcagtg aagtgatggc tgatttacgt cagactattc caggatttag
     5401 agaggaccat gcgaccattg tccatggaga tgtacgacat agtaattgga ttgagacaga
     5461 tagtggcttg atttatttag tagattggga ttcggttcgc ttgaccgatc gcatgtttga
     5521 tgtggcccat atgctctgcc attatatttc agaacatcag tggaaggaat ggttgaccta
     5581 ctacggttac aagtacaatc aaacggtatt aagtaaattg tattggtatg gtcaattgtc
     5641 ttatttgagt cagatttcca agtattatat gaaccaagat ttagaaaatg tcaatcggga
     5701 gattcatggt ttgcgtcatt tccgagacaa gtatggaaag agaagatgag agttagaaat
     5761 cgtaaagggg caacagaatt actagaggca aatccccagt atgtggtcct caatcccttg
     5821 gaagccaagg caaaatggcg ggacttgttt ggcaatgata atcccattca tgtggaagtt
     5881 ggaagtggaa agggtgcctt tgtttcaggt atggccaagc aagaccctga catcaactat
     5941 atcgggattg atattcaaaa gtctgttttg agctacgctt tggacaaggt gcttgaagtt
     6001 ggagtgccta acatcaagct cttgtgggta gatggttctg acttaactga ctactttgaa
     6061 gacggtgaga ttgatcgctt gtatctgaac ttttcagatc catggccgaa aaaacgccat
     6121 gaaaagcgtc gtttgaccta caagaccttc ttggatacct tcaaacgtat cttgcctgaa
     6181 aatggagaaa ttcatttcaa gacggataac cgtggcttgt ttgagtacag tttagtgagc
     6241 ttttctcaat atggcatgaa actcaatggt gtctggttag atttgcatgc cagtgatttt
     6301 gaaggcaatg tcatgacaga atacgagcaa aaattctcaa acaaggggca agttatctac
     6361 cgagttgagg cagaatttta agagatagcc taaaattagg ctgtacaagt gcttttgctt
     6421 tacataagtt ggcaaacgtg ctatactgat agtaagaata tgaaaagtga ggcggggaaa
     6481 tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc aacaatcgta gaattagtca
     6541 gagaagttgt agaacctgtc atagaagctc cttttgaact cgtggatatc gagtatggaa
     6601 agattggcag tgacatgatt ctcagtattt ttgtagataa acccgaagga attaccttga
     6661 acgacacggc agacttgaca gaaattatca gtcctgtcct agacaccatc aagccagatc
     6721 ccttcccaga acaatatttc ctagaaatta ccagtccagg tttggaacgc cctttgaaaa
     6781 ccaaggatgc cgtcgctgga gcggttggaa aatacatcca tgtcgggctc taccaagcca
     6841 tcgataagca aaaggtcttt gaaggaacct tgttggcctt cgaagaggac gagttgacta
     6901 tggaatatat gggcaagacg cgtaagaaaa ccgtccaaat tccatacagt ttagtatcaa
     6961 aagcacgttt agcagttaaa ttatagaaaa agaaaggata gcttttgagg attcaaaagt
     7021 gaagaaaaca tgagtaaaga aatgctagag gccttccgca ttttggaaga agacaaggga
     7081 atcaaaaaag aagatatcat cgacgcagta gtagagtcgc ttcgttccgc ttatcgcaga
     7141 cgctatggtc agtcagacag cgtagctatt gacttcaacg aaaaaacagg tgactttaca
     7201 gtttatactg tccgtgaagt tgttgatgaa gtatttgata gccgtttgga aatcagcttg
     7261 aaagatgctc ttgccattaa ttcagcttat gaacttggag acaaaatcaa gtttgaagaa
     7321 gcaccagctg agtttggtcg tgtagcagcc caatctgcca aacaaaccat catggaaaaa
     7381 atgcgcaagc aaacacgtgc catcacttac aatacttaca aagaacatga gcaagaaatc
     7441 atgtctggta cagtagaacg ctttgacaac cgctttatct atgtcaacct tggtagcatc
     7501 gaagcccaat tgtcaaaaca agaccaaatt cctggagaag tttttgcttc tcatgatcgt
     7561 atcgaagttt atgtttacaa ggttgaagac aaccctcgtg gtgtgaacgt ctttgttagc
     7621 cgtagccatc cagaaatgat caaacgtttg atggagcaag aaattccaga agtttatgat
     7681 ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg accgtacgaa ggttgctgtt
     7741 cgtagccaca atccaaacgt ggatgctatc ggtacaatcg ttggacgtgg tggtgctaat
     7801 atcaagaaga ttactagcaa attccaccca gctcgttacg atgctaaaaa tgaccgcatg
     7861 gtaccaatcg aagaaaatat cgatgttatc gagtgggtag cagatccagc tgaatttatc
     7921 tacaatgcca tcgctcctgc tgaggttgac caagttatct ttgatgaaaa cgacagcaaa
     7981 cgtgccttgg tggttgttcc agataacaag ctttctcttg ccattggtcg tcgtggacaa
     8041 aacgtgcgct tggcggctca cttgactggt taccgtatcg atatcaagtc tgctagcgaa
     8101 tttgaagcca tggaagacgc tgcttcagta gagttggaag tagaaaacga tactgtagaa
     8161 gaataaaagc tgctagagga gggaaagatg aaaacaagaa aaatcccttt gcgcaagtct
     8221 gttgtgtcta acgaagtgat tgataagcgt gatttgctcc gcattgtcaa gaacaaggaa
     8281 ggacaagtct ttattgatcc tacgggcaag gccaatggcc gcggcgctta tatcaaacta
     8341 gacaatgcag aagccctaga ggcgaaaaag aagaaggtct ttaaccgcag ctttagcatg
     8401 gaagtggaag aaagctttta tgacgagttg atcgcttatg tggatcacaa agtgaaaaga
     8461 agagagttgg gacttgaata agcaaaagat aagtaatctc ttggggcttg ctcagcgagc
     8521 agggcgcatc atatcgggtg aagaattggt ggtcaaggcc attcaagacg gcaaggccaa
     8581 gttggtcttt ctagctcatg atgctggacc caatctgacc aagaagattc aagataaaag
     8641 tcattattat caagtagaaa ttgtaaccgt gttttcaaca ctggaattaa gcatagcagt
     8701 cgggaaatcg agaaaggttt tggctgtaac agatgctgga tttacaaaga aaatgaggtc
     8761 tcttatggaa tagaagagga ggacatgatt tgtctaagaa aagattgtac gaaatcgcaa
     8821 aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc aaaagagttg ggcttggatg
     8881 tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc aaaaattgct gccagcttta
     8941 agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc accaaaagta agtgcagaaa
     9001 agaaaaccga aaaatctgag ccagctaaac cagctgtagc taaggaagag gcaaaaccgg
     9061 ctgagccagt tgctccgaaa acagaaaaag tagcagcgaa accgcaaagc cgtaatttca
     9121 aggctgagcg tgaagcccgt gctaaagagc aggcagaacg acgcaagcaa aataagggca
     9181 ataaccgtga ccaacaacaa aacggaaacc gtcagaaaaa cgatggccgt aatggtggaa
     9241 aacaaggtca aagcaaccgc gacaatcgtc gctttaatga ccaagctaag aagcagcaag
     9301 gtcagcaaaa acgtagaaat gagcgccgtc agcaagagga caaacgttca aatcaagcgg
     9361 ctccacgtat tgactttaaa gcccgtgcag cagccctaaa agcagagcaa aatgcagagt
     9421 acgctcgttc aagtgaggaa cgcttcaagc agtatcaggc tgctaaagaa gccttggctc
     9481 aagctaacaa acgcaaggaa ccagaggaaa tctttgaaga agcggctaag ttagctgaac
     9541 aagcacagca agttcaagca gtggttgaag tcgtccctga gaaaaaagaa cctgcagtgg
     9601 atacacgtcg taaaaaacaa gctcgaccag acaaaaatcg tgacgattat gatcatgaag
     9661 aagatggtcc tagaaaacaa caaaagaatc gaagtagtca aaatcaagtg agaaatcaaa
     9721 agaatagtaa ctggaataac aacaaaaaga acaaaaaagg caataacaag aacaaccgta
     9781 atcagactcc aaaacctgtt acggagcgta aattccatga attgccaaca gaatttgaat
     9841 atacagatgg tatgaccgtt gcggaaatcg caaaacgtat caaacgtgaa ccagctgaaa
     9901 ttgttaagaa acttttcatg atgggtgtca tggccacaca aaaccaatcc ttggatgggg
     9961 aaacaattga actcctcatg gtggattacg gtatcgaagc caaacaaaag gttgaagtgg
    10021 ataatgctga catcgaacgt ttctttgtcg aagatggtta tctcaatgaa gatgaattgg
    10081 ttgagcgtcc accagttgtt actatcatgg gacacgttga ccacggtaaa acaacccttt
    10141 tggatactct tcgtaactca cgtgttgcga caggtgaagc aggtggtatt actcagcata
    10201 tcggtgccta ccaaatcgtg gaaaatggta agaagattac cttccttgat acaccaggac
    10261 acgcggcctt tacatcaatg cgtgcgcgtg gtgcttctgt taccgatatt acgatcttgg
    10321 tcgtagcggc agatgacggg gttatgcctc agactatcga agccattaac cactcaaaag
    10381 cggccaacgt tccaatcatc gtagccatta acaagattga taaaccaggt gctaacccag
    10441 aacgcgttat cggtgaattg gcagagcatg gagttatgtc aactgcttgg ggtggagatt
    10501 ctgaatttgt tgaaatctca gctaaattca accaaaatat cgaagaattg ttggaaacag
    10561 tccttcttgt agctgaaatc caagaactca aggcagaccc aacagtgcgt gcaatcggta
    10621 cggttatcga agcgcgcttg gataaaggaa aaggtgcggt cgcaaccctt cttgtacaac
    10681 aaggtacctt gaatgttcaa gacccaatcg ttgtcggaaa taccttcggt cgtgtccgtg
    10741 ctatgaccaa cgaccttggt cgtcgtgtta aagttgctgg accatcaaca ccagtctcta
    10801 tcacaggttt gaacgaagca ccgatggcgg gtgaccactt tgccgtttac gaggatgaaa
    10861 aatctgcgcg tgcagcaggt gaagagcgtg ccaaacgtgc cctcatgaaa caacgtcaag
    10921 ctacccaacg tgttagcctt gaaaacctct ttgataccct taaagctggg gaactcaaat
    10981 ctgttaatgt tatcatcaag gctgatgtac aaggttctgt tgaagccctt tctgcctcac
    11041 ttcaaaagat tgacgtggaa ggtgtcaaag tgactatcgt ccactcagcg gtcggtgcta
    11101 tcaacgaatc agacgtgacc cttgccgaag cttcaaatgc ctttatcgtt ggtttcaacg
    11161 tacgccctac accacaagct cgtcaacaag cagaagctga cgatgtggaa atccgtcttc
    11221 acagcattat ctacaaggtt atcgaagaga tggaagaagc tatgaaaggg atgcttgatc
    11281 cagaatttga agaaaaagtt attggtgaag cagttatccg tgaaaccttc aaggtgtcta
    11341 aagtgggaac tatcggtgga tttatggtta tcaacggtaa ggttgcccgt gactctaaag
    11401 tccgtgttat ccgtgatggt gtcgttatct atgatggtga actcgcaagc ttgaaacact
    11461 ataaagacga cgttaaggaa gttacaaacg gccgtgaagg tggattgatg atcgacggct
    11521 acaatgatat taagatggat gatgtgattg aggcgtatgt catggaagaa atcaagagat
    11581 aagatttttt gctcctttct taggtggtga gggacgcaag caaaccgatg gtttcattgc
    11641 ttatttttga gcctagggtc tcaaaaatcc cctgtgatgg gactgataaa tcagttccat
    11701 cactttcacc acggcgaaag aagcagatga cttcaaattg aacttcgttt caatttaaac
    11761 tgaaaatcaa gaagtttaaa atagctaggt ctgctggcct agcttttggt tcaaagtaga
    11821 gaaaggaata tcatggcaaa tcatttccgt acagatcgtg tgggcatgga aatcaagcgt
    11881 gaagtcaatg agattttgca aaagaaagtc cgtgatccac gtgtccaagg tgtgaccatc
    11941 acagatgttc agatgctggg tgacttgtct gttgccaagg tttattacac cattttgagt
    12001 aaccttgctt cggataacca aaaagcccaa atcgggcttg aaaaagcaac tggtaccatc
    12061 aaacgtgaac ttggtcgcaa tttgaaattg tacaaaatcc cagatttgac cttcgtcaaa
    12121 gacgagtcca tcgagtatgg aaacaagatt gacgagatgc tacgcaatct ggataagaac
    12181 taaagaagag gggttgcccc tcttttttgg tggaggaaaa taggttgaat ttgaaatgga
    12241 aaaatattct tttaaaatat attgaaacta gaatagtac
//
LOCUS       DAVKUR010000055        12013 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKUR010000055 DAVKUR010000000
VERSION     DAVKUR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.055"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            122..277
                     /locus_tag="VW749_001757"
                     /pseudo
     CDS             122..277
                     /locus_tag="VW749_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VW749_001758"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VW749_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0175756.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VW749_001759"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VW749_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0175757.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFCFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     HVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VW749_001760"
     CDS             7614..8792
                     /locus_tag="VW749_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175758.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSIC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9001..>12013
                     /locus_tag="VW749_001761"
     CDS             9001..>12013
                     /locus_tag="VW749_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0175759.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVE
                     PEKVEAPKEYTGKIEQPSAEDTKPENGASSTNGESERPKDKIKEEKQVDKKLELRNVS
                     NVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVY
                     KIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGA
                     TMDAREVELPDDQESYVKNEFYGKLIGKNNGKYYAIYNLKKPLFKTLNTATIQNLSIK
                     EANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGR
                     ITNTYDTTAGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSA
                     TIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAIAG
                     YNFNGIKTIETYSNKNNKVVNVVQEDDEVVTKDSDVQRGTVLDADKVKEKKIELVSKH
                     STKVEDFDFTSRYNTNYNEVTGYQQSREQVYK"
BASE COUNT         3955 a         2311 c         2504 g         3243 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cgaacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 accatgagat gaccaaatct cagatgaatt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaagggc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc gccttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgctga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcccgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagcat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga cttgtatatt gacctcagtc
     1681 agtctgatat tgatgctttt gaacaatata tccgctatct tggtattaat ggcttgccag
     1741 cctttcagca aaccttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttttg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggaaaaacc taaaccaaac gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatcagca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcat cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggga gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg tagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggttgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc gccagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtacttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgtgctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagaaaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatcctcaa gaaggcaagc tcattctcct caaggaaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac atgcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggctgaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg gattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttt gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 accccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaatcca aggaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacacgttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgactgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 tttgtgtctg tggaaatgtc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat taaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaaac agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaaatggtg
     8581 aagtaccctt ttcaactgaa tacctgtcag atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacta tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttctata gataatagat
     8941 aatacactaa tataataaag gtctttgtaa catatataaa ttttatttca aggaggaata
     9001 atggaaaagt attttggtga aaaacaagag cgtttttcat ttagaaaatt atcagtagga
     9061 cttgtatctg caacgatttc aagtttattt tttatgtctg tattagctag ttcatctgtg
     9121 gatgctcaag aaactgcggg agttcactat aaatatgtgg cagattcaga gctatcatca
     9181 gaagaaaaga agcagcttgt ctatgatatt ccgacatacg tggagaatga tgatgaaact
     9241 tattatcttg tttataagtt aaattctcaa aatcaactgg cggaattacc aaatactgga
     9301 agcaagaatg agaggcaagc cctagttgct ggtgctagct tagctgctct gggaatttta
     9361 atttttgctg tttccaagaa aaaggttaag aataaaacgg tattacattt agtattggtt
     9421 gcgggaatag gaaatggtgt cttagtttca gtccatgctt tagaaaatca tcttttgcta
     9481 aattacaata cggactatga attgacctct ggagaaaaat tacctcttcc taaagagatt
     9541 tcaggttaca cttatattgg atatatcaaa gagggaaaaa cgacttctga ttttgaagta
     9601 agtaatcaag aaaaatcagc agccactcct acaaaacaac aaaaggtgga ttataatgtt
     9661 acaccaaatt ttgtagacca tccatcaaca gtacaagcta ttcaggaaca aacacctgtt
     9721 tcttcaacta agccgacaga agttcaagta gttgaaaaac ctttctctac tgaattaatc
     9781 aatccaagaa aagaagagaa acaatcttca gattctcaag aacaattagc cgaacataag
     9841 aatctagaaa cgaagaaaga ggagaagatt tctccaaaag aaaagactgg ggtaaataca
     9901 ttaaatccac aggatgaagt tttatcaggt caattgaaca aacctgaact cttatatcgt
     9961 gaggaaacta tagagataaa aatagatttt caagaagaaa ttcaagaaaa tcctgattta
    10021 gttgaaggaa ttgtaagagt aaaacaagaa ggtaaattag gtaagaaagt tgaaatcgtc
    10081 agaatattct ctgtaaacaa ggaagaagtt tcgcgagaaa ttgtttcaac ttcaacgact
    10141 gcgcctattc caagaatagt cgaaaaaggt actaaaaaaa ctcaagttat aaaggaacaa
    10201 cctgagactg gtgtagaaca taaggacgta cagtctggag ctattgttga acccgcaatt
    10261 cagcctgagt tgcccgaagc tgtagtaagt gacaaaggcg taccagaagt tcaaccagcg
    10321 ttgtccaaag cagttataac cgacaaaggt gagactgagg ttcaaccaga gtcgccagat
    10381 actgtggtaa gtgataaagg tgaacctaaa caggtagcac cgcttccaga atatacagga
    10441 ccacaagcca gcgctattgt tgaaccagag caggtagcac cactaccaga atacacaggg
    10501 gtacaagccg gatcgatagt cgagccagag aaagtagaag caccgaaaga atatactggt
    10561 aaaatcgaac agcctagtgc agaagatact aaacctgaaa atggggcaag ctctacaaat
    10621 ggggaatcgg aacgtcctaa agataaaatt aaagaagaaa aacaagtcga caagaaacta
    10681 gaacttagaa atgtttcaaa cgtggaatta tatacggtag aaaataataa atatcgacat
    10741 attacggctg tagatggtgc tttagatagt tcattgaagt atttcatgaa ggtaaaatca
    10801 gaaaatttta aagatataat gttgcctgtt actaaaattg aaagtacaac aaaaaacaat
    10861 aaagaagtat acaaaattgt ggctcatgca gaaaatctaa ttcaacacga aaacaatgtt
    10921 atttcgaatg actatacata ttatttacca aaaactcagc aaagtgaaac tggcgtctat
    10981 acatcattta aaaatttagt tgatgcaatg aatagtgacc ctaatggaac attccattta
    11041 ggtgcaacta tggatgctcg tgaagttgaa cttccggatg atcaagaaag ttatgtaaaa
    11101 aatgaatttt acggaaaatt aataggtaaa aataatggta agtattatgc tatttataac
    11161 ttgaaaaaac ctttatttaa aactctaaac accgctacta ttcagaatct ttcaataaaa
    11221 gaagcgaatg tttcttctaa agaagatgct gctacaatat cgaaagaagc aaaatacaat
    11281 actcttatag ataatgttca ttctgatggt attatagctg gtgaacgtgg aattggtgga
    11341 ttggtttcaa aagtagataa ctcgagaatt tctaatagta gttttacagg cagaataact
    11401 aacacatatg atacaactgc agggtatgaa attggtggtt tagtaggtaa actttctggt
    11461 tcgcttgctt ctatagagaa atcaatagca tcgattgaca tagcctctaa tgcaaaatca
    11521 ggagatcaaa ttgttggtgg tatagccgga gttgttgaga aaagtgcgac aattaagtat
    11581 agctatgttg aaggaaatgt taacaatgtg cgacactttg gtaaagttgg gggagttgca
    11641 ggtaatcttt gggatagaga ttcacaagat gtaagtaaat caggtaaact atcatatgtt
    11701 ttaagtgatg tcaatgttac gaatggtaat gctatagctg gctataattt caatggaata
    11761 aaaacgattg aaacatatag caataaaaat aataaggtag taaacgtagt acaagaagat
    11821 gatgaggttg tgactaaaga ttcagatgta caaagaggta cggtattaga tgctgataaa
    11881 gtaaaagaga aaaagataga attggtttct aaacacagca ctaaagtaga agattttgat
    11941 tttacttcaa gatacaatac taattacaat gaagtaacag gttaccaaca gtcgagagaa
    12001 caagtatata aaa
//
LOCUS       DAVKUR010000056        11765 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKUR010000056 DAVKUR010000000
VERSION     DAVKUR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.056"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..204
                     /locus_tag="VW749_001762"
     CDS             <1..204
                     /locus_tag="VW749_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175760.1"
                     /translation="LNTSIRSAYSGSDITPVYSLGSGSRIVMYYNGGGDNYIGSGTRL
                     AMAPQFGNHVRIHTSGSWSPDSY"
     gene            263..937
                     /locus_tag="VW749_001763"
     CDS             263..937
                     /locus_tag="VW749_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEV0175761.1"
                     /translation="MLHPIFIIRRSWDGIFHLSEWKRNEEFDFFNKMDVPYLSMSSRI
                     EVTQAINFHKKHSISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTS
                     EDKLNFSSFTMGDNLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVST
                     PMNLSKIDTVPRITWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKIN
                     EYFQKK"
     gene            1005..2642
                     /locus_tag="VW749_001764"
     CDS             1005..2642
                     /locus_tag="VW749_001764"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0175762.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            2743..3510
                     /locus_tag="VW749_001765"
     CDS             2743..3510
                     /locus_tag="VW749_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEV0175763.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIVIPIFYNDDSELTEFPIEFFNKS
                     DAGFQHMIKTYDQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIASLFL
                     LYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEEYIN
                     RVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
     gene            4527..5519
                     /locus_tag="VW749_001766"
                     /pseudo
     CDS             4527..5519
                     /locus_tag="VW749_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            5521..6338
                     /locus_tag="VW749_001767"
                     /pseudo
     CDS             5521..6338
                     /locus_tag="VW749_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            6340..7125
                     /locus_tag="VW749_001768"
     CDS             6340..7125
                     /locus_tag="VW749_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175764.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(7504..8699)
                     /locus_tag="VW749_001769"
                     /pseudo
     CDS             complement(7504..8699)
                     /locus_tag="VW749_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            9201..9404
                     /locus_tag="VW749_001770"
     CDS             9201..9404
                     /locus_tag="VW749_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0175765.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            9535..9687
                     /locus_tag="VW749_001771"
     CDS             9535..9687
                     /locus_tag="VW749_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175766.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            9854..11647
                     /locus_tag="VW749_001772"
     CDS             9854..11647
                     /locus_tag="VW749_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0175767.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
BASE COUNT         3949 a         1682 c         2249 g         3885 t
ORIGIN      
        1 ttaaatacct ctattcgtag cgcctatagt gggtcagata ttaccccggt atattcattg
       61 gggtctggct ctaggattgt catgtactat aatggaggtg gtgacaatta tattggttct
      121 ggtactagat tagctatggc gccacaattt ggaaatcatg taagaattca tacttcaggt
      181 tcttggagtc cagattctta ttaacttact tgtcagagta agccttaaag atggttgatt
      241 gtgggtgtag catgaaaaaa gaatgctaca ccctattttt attataagga ggagttggga
      301 tggaattttt catttatcag agtggaaaag gaatgaagaa tttgactttt tcaataaaat
      361 ggatgttcct tatttatcta tgagttcacg aatagaagta acgcaggcta tcaattttca
      421 taaaaaacat tcgatatcac tttatgccat aatatcgtgg tgtgttatga gtgcaataaa
      481 ttctattcca gaattactaa tggataccga cggaaagatt gtctggcaat acaatcaaag
      541 aggttgttct ttcactaccc ttacatcgga agataagctt aatttttctt catttacgat
      601 gggagataat ttaattgaat ttgtttctgc gttcaacata aataaacaga aggcagaaga
      661 agggcaaaaa ccaaatattg acaagaataa cattgcttat ctttcttgtg ttccatggat
      721 tgatttttta catgtaagca ctcctatgaa tctttcaaaa attgatacag ttcctcgaat
      781 aacgtgggga aaagttattc aagagaacca aagatatttt tgtacagtga atttacaaat
      841 taatcatgga atgggagatg gattacacgt atctaatttt tttgtgttat tgcaaaggtt
      901 tgtaaataaa ataaatgaat attttcaaaa aaagtaatga ttgaaaagat attgcattta
      961 aataatgtta taataaaaat aaagaattta aggagaaata caatatgtca atttttattg
     1021 gaggagcatg gccatatgca aacggttcgt tacatattgg tcacgcggca gcgcttttac
     1081 cgggggatat tcttgcaaga tactatcgtc agaagggaga ggaagtttta tatgtttctg
     1141 gaagtgattg taatggaacc cctatttcta tcagagctaa aaaagaaaat aagtctgtga
     1201 aagaaattgc tgatttttat cataaggaat ttaaagaaac ttttgaaaaa ttaggtttta
     1261 catatgactt gtactcgcga acagattctc cactacatca tgagatagta caagaattat
     1321 ttttgcaatt atacgagaag aaatttttgt atacaaaaaa aattaaacaa ctctattgta
     1381 catttgataa tcaattctta cctgataggt tcgttgaagg aaaatgcccg aattgtggaa
     1441 cccattcaag aggagatcaa tgtgataatt gctcagcaat tttagatcct atagatttag
     1501 ttgataaaag atgttctatt tgttccaatg aaccagaagt tcgtgagaca gaacactttt
     1561 attatgtttt tagtgagttt caaaatttgt tagagactta cttaaatgat gctgaagaaa
     1621 cagtgagatg gcgaaaaaat gcaataaatc taactaaaag gtatttacgg gaaggtttac
     1681 ctgatcgagc tgttactcgt gatctaccaa atgggattcc agttcccatt gatggtttta
     1741 gagataaaaa aatatatgtc tggtttgaag cggtagcagg ttactacaca gcaagtgttg
     1801 attgggcgca aaaacttcaa aataatatta ctgatttttg gaacaatcgg acaaagtcat
     1861 attatgttca tggaaaagat aacatcccat ttcatactat tatttggccg gcaatactct
     1921 caggtttaga aatagagcct cttccagagt atattatttc tagtgaatat ttaacgttag
     1981 aaaacaaaaa aatatcaaca agtaataatt gggctatatg gcttaacgat atcataaaaa
     2041 aatatgatgc tgattcaatc cgatacttcc taacaataaa tgctcctgag atgaaagatg
     2101 caaatttttc ttggagagaa tttatttata gtcataactc agaattatta ggatcgtacg
     2161 gtaattttat caataggact ctaaagttta ttgaaaagta ttttgaatct gaaataccca
     2221 ctaaatatct cgaaggagaa attttatata atttgaaaga attatataca acagtaggta
     2281 atttagttga gagcgggcat atgaaacagg cattagaaga aatttttgaa tatattagat
     2341 cggctaataa attctatgat gatatgaaac cgtgggcatt gcgagagtcc gatattgaaa
     2401 aatgtaaaga agtcttagct acttgtgtaa tcattatact taatttagga caaatgttaa
     2461 atccattcat tcctttttct ggtaaaaaga ttgaggatat gtttaaaaca aagctaaata
     2521 cttggaatta tatttcaaac cttcctaaca agctatcaga tgtatcaatg ttgtttgata
     2581 ggattgattt gaaaaaaatt gacgaggaag ttttagaatt gcaacaaaca tccagtagat
     2641 aattcaaaaa tactcgaaag tagccttttt taatttaaat taacaaccgg agatgttgaa
     2701 taaaataaag atggtttttt gagcatatta tggagaaaag cattgaataa tctaacttta
     2761 ctaaaagaat ataattttag agatcttgga aaccacctca ctcaaacagg acaaaaaata
     2821 aaacctaaaa cattattccg ttcaagtaaa ctatttggaa tctctaaaat tgatgtcgat
     2881 ttgttacaga gctatggaat aacaaaagtc attgactttc gatcagcgaa tgaaataaaa
     2941 aaagctccag atccagatat aaaaaatata aaaaatatag taattccaat attctataat
     3001 gatgattcag agttgacaga attcccaata gaatttttta acaaatcaga tgcaggtttt
     3061 caacatatga taaaaactta tgatcaaatg atcaatcaaa aacagagtaa acttggttac
     3121 aagaaattct ttaaattatt actaagtcat ccaaaagatg aatctctttt gtttcattgt
     3181 tcaatgggga aggatcgaac aggaatagct agcttgttct tgctttatat attgggagta
     3241 gatatgaacg atatttttca tgattactta ctatctaaca agtatttaat aaatgtgaga
     3301 aaagaaaata ttgaatatgt aaataaccat agtgggaatg taatattgat gcataattta
     3361 ctttcactca gttcagcaaa agaagaatat attaatcgag tattgaatgt ccttgataaa
     3421 gaatatggag gaatacttag atatattaat acagaactag gaataagtag tcaagaaatt
     3481 gaggaattga aagatagata tcttttttag aatagtaagt actaaaaatg aatatataac
     3541 agtgcgaacg gcggttttgt ttttgtctaa ttctactaat ttaacataag caaaaacgga
     3601 ttgttttcta tgtaagtcct taactaaatt gatggaaagc acgttaaatt atgtgcaaaa
     3661 tgcgtacaaa atagtgttta tcaaatgtaa aatttcctac ttgtcatcaa agttcaacaa
     3721 atgtaggttg tttggttatt tgggtagatt tctggactta tcgttggttg tagagacata
     3781 atgttgcagt taaagcttag agaataatct ccgtattttt gttaggcaat ttaaaagtta
     3841 agacaaagtg agtttgtctc ttaattcaac tcaccacaaa cacatcacct ttttattata
     3901 acttccgacc aatttttttg aagagaaaaa tgaaaaaaca ccaactgtgc agggtagctg
     3961 acaaggcttc tagcttccat ttattgaaac caaatcaatc tgttatgaga taatagcagt
     4021 tgcagaagct gactactttg agaagttaaa tgaggtttat tatcaagaat acttcatgaa
     4081 tatagttata agggaggggg tagttgaaag aattgactca tctgttaaaa taaaaatgga
     4141 aataataaca tcataatagt gtgacttagt atttttcagc atcttggaag taggtaaatg
     4201 atattaaaat tatactgcat agtaaaggat agtaatgagg aatttaatat cttcctgtca
     4261 atatcttcag ttattaaagt atttttatat tgggataact tcgtttgctg aaatctatag
     4321 tttatccaat tataaattta tatgttcttc gtcataattc tttgtacttg agtaatttag
     4381 cttacttaca gataaaatac aagatggcat agttttagta gcttttttca tatggtttgt
     4441 aatgatggta aattttctta actttactgt agtatgctac aatttttgtt gatattataa
     4501 cttgagtgaa acgaaaggag tgatttataa aaatgataac agtagagcat cttcagaaaa
     4561 attttgtgaa aacaataaag gaacctggct taaagggagc ttttcgctct ttttttcatc
     4621 ccaagagaca agtctttgaa gctgttaaag atttatcatt tgaggtgccc aaaggacaaa
     4681 ttttaggctt tattggcgca aatggagcgg ggaaatcaac aactatcaag atgttgacgg
     4741 ggattttgaa accaacatca ggtttttgtc gtatcaatgg aaagattcct caagagaacc
     4801 gtcaaggcta tgttaaagat attggtgtag tttttgggca gcgaactcaa ctttggtggg
     4861 atttggcttt gtaggagact tactcggttt taaaggaaat ttatgatgtt cctgatgcgg
     4921 tctttcaaaa acgcatggat tttctaaatg aagttttaga tttgaaggaa tttattcaag
     4981 atcctgtcag aactctatct ctaggtcaac gtatgagggc ggatattgcg gcctccttat
     5041 tgcataatcc gaaagttctt ttcctagatg agcctactat tggtttagat gtttcggtca
     5101 aggataatat tcgacgtgcc attacacaga ttaatcaaga agaagagacg accatacttt
     5161 taacgaccca cgatttaggt gatattgaac agttatgtga tcgtattttt atgattgata
     5221 agggccgaga aatctttgat ggaactgtga atcaactgaa aaagactttc gggaagatga
     5281 agactctctc ttttgaacta catcctgggc aggattatat tgtctctcat tttgaaggac
     5341 tttctgatat ctatgtgacg agacaggaat tgtcacttga tattcagtac gacagctcgc
     5401 agtatcaaac ggctgacatt attcaacaaa ctttgtctga ttttacgatc cgtgatttaa
     5461 agatgacgga tgcgaatatt gaagatatta ttcgtcgctt ctatcgaaag gagctttagg
     5521 atgactaaat tatggaaacg ctataagcct tttgttagcg ctggaatcca agaattaatc
     5581 acgtatcgtg tcaatttttt tctttatcgc attggggatg tgatgggggc ctttgtagca
     5641 ttttacttgt ggaaagctgt gtttgattca tctcaccagt ctctcattca aggttttact
     5701 ttatctgata tgaccttata tatcatcatg agttttgtga cgaatctact gacaaaatca
     5761 gatagttctt ttatgattgg atgggaagta aaggatggct ctattattat gcgactgctt
     5821 cgtccagttc attttgcaat gtcttatctt ttcacagaaa ttgggtctag atggctagtt
     5881 tttgttagtg ttggtctacc atttgtaatt ctgattgcag gtctaaagct cttatcaggt
     5941 gagtccttct tacaaattgt tttaataacc acagtttacc ttcttagctt aatcttagct
     6001 tttttgatta attttttttc aatatttgct ttggtttttc agcttttgtg tttaaaaact
     6061 tatggggatc aaatcttttg aaaaattctt tagttgcctt tttatctgga agtttggttc
     6121 ctctgacatt ttttccaaaa attattgccg aactattatc ttttttgcca ttttcttctt
     6181 taatctatac cccggtgatg gttattatag aaaagtatag catgagtcaa atgattcagg
     6241 cgctctcgct acaattattc tggctgttta ttatgattgc cttatcccaa ctgatttgga
     6301 agtgcgtaca gaattatata actattcaag gaggttagaa tgaagaaata tcaacgcatg
     6361 cacctgattt ttatccgaca atatcttaaa cagattatgg agtataaggc tgatttttta
     6421 gttggtgttg tgggtgtctt tttgacacaa gggttaaaca tgctgtttct aaatattttg
     6481 tttcaacata ttcccttact tgatggctgg agttttcatc aggttgcttt tatttatggt
     6541 ttttctctca ttcctaaggg aattgaccat ctcttttttg ataatctgtg ggctttagga
     6601 caacatttaa ttcgtaaagg agaatttgat aagtatttga ctagacccat tagccctttg
     6661 tttcatattt tagtagaaac gtttcaaatt gatgctcttg gagaattgtt agtaggcgtc
     6721 ttattgctgt taatgacaat aactagtctt acttggactt gggcaaaggt ttttctcttt
     6781 ttaatcagta ttccctttgc aaccttaatt tatacctctt taaaaattgt aacagctagt
     6841 attgcttttt ggactaaaca atctggggca ataatttata ttttttacat gtttaatgat
     6901 tttgcaaaat acccgattgc gatttaccat tcgtttttac gttggttgat tagttttatc
     6961 attccttttg cttttacagc ctattaccca gctagctatt tcttgaaaga caaggatgga
     7021 ttgttcaata ttggtggatt gatccttatc tcattaatat tttttacctt atcattaaaa
     7081 ttatggaaca aaggtttgga tgcatatgag agcgcagggt cttagaagaa gtaaaatcta
     7141 attaagaatt ttgatagaac ttcctattct ttggaaggaa gttttaatga tacattgaga
     7201 gctttgatta ggcttactgt agtttttcaa acaagaaatt tgaccattgt gcaaaaatga
     7261 tacaaaggta tgtaatattt cagtcataac cactcgttca tatcatgagt ggttttttag
     7321 ctcttttata cataccattt gttaagggac atacgatatt ctagctcaaa aggttttctg
     7381 aatgagtatc aaaggaatgt ttagaagata attgcgagct gttttttgaa atttgggcac
     7441 acttaaaaga cacttatctg gtattaaaaa ataaggtgtt acaatgatag gacatagatg
     7501 actttaatga ctttgggtta aagtgtagtc gtaaagtttg ttatgcgtta tgaggtaata
     7561 cattgtccgg atgaggcgat gtatagagac aatcgtatat ggcttggttg aagtcgtctg
     7621 cgattgtctt tttcgtttct cataaaagtc cgcgatatga caaggattgg tatgactagc
     7681 tgaagcaata ttgtggacgc acttatagag aatttttctc gcgtaaggat ttccacgctt
     7741 ggtgatatgt tcttgagcta ggaaattgcc agattcatag tgtctgaggt caatactgat
     7801 aaaggcattg atttggttgg cagaccgaaa gcgacgaatg tctccaattc gccaataatg
     7861 cttgtagctg ttgtttctgc gataccagga atagagagca gaatctcgta ttcaggtaat
     7921 ggttcagcca attcaatcat ttgtgctaag tcctgatcct tgcggtttgt cagtctcaac
     7981 agttcctgtg catgatactt aacctcttct gtcatgggag aggtttttga aatggcaaga
     8041 taggactgtt cggccagctc gctcaacttt tcagccaatc gtccaactct gttctcagaa
     8101 atccgtttag aagttgaatt acgatggctt cttttagctc aactactgat aatttcagcc
     8161 tccaatgctt ggttggaaag atggtcacga ggttccaata ttgttcccct gtaggagtag
     8221 agagaaggtt ctttatttct ggaaaggcaa tttgaagcac cttgtgcagg ctattcttag
     8281 tcctaacgat gtcttctgtc agattctgat agaatcgact gaggtcacgc aaattttgat
     8341 agacttcttc ttgaacataa gttggtttgc ggttaaggat gaattgtgac gaagctagct
     8401 tttcagcgtc aatctgattg gttttacgga ctcgcaaact gtctagttgc ttcttagttt
     8461 taaaggattt agccgtatat aagcatagct attgtcctcc agaaaggcct gaagacgaga
     8521 atagacccct gtgcctcgaa gataatctca ggtgtattta cctatttcaa atcctctaga
     8581 agacgactaa atccgatggc atcattgggc atggtatagc catgaacctt ttcaccattc
     8641 acaagaatag cgacttctga gcttgcctta ctcacatcca ttctgaaaac tgtccgcatc
     8701 atgtttaccc ctttgtcttg aatgactcct tgttttagtg attttatttc caatactcga
     8761 cgtctagtat cccacatact ttgataaaat tcttcctaaa acaggtttct tgccagtttg
     8821 tcaagcgacg tctagcacca tagagagctc tatgacttaa caagacacca ctattttaac
     8881 acaaagaaaa agtaatgagt actctctccc gttggagatt tcctcactac taatcttagt
     8941 atgtttgtca actgtagtga tagacgaata atcaagttct ggagaaggtc agattgggcg
     9001 attacttatt attttcctag cttgtacggt gcttttatcg ctatgaaaaa gtttattcca
     9061 aaatcttttt ttagtaactt atagcttact tactgttata ccaactattt ctaaaatctt
     9121 ataaattatt ttatgcatat tttgcataaa attccaaatt tgataatctt caaattacaa
     9181 tattagtaag aggattatta atgtatatca gattaaagaa tttaagagaa gacaaagatt
     9241 tgtcccagtg tcaaattgca cagtatcttc attgttcaca gtctgcttat tctagaatag
     9301 aaagtggcaa gcaagatatt cctacatcat ttttgaaaca attagctaaa ttatatcagg
     9361 taactacaga ttatatttta gagatggata agtttagttg ttaataaatc ctaagccctt
     9421 tgaaaactga ataaaccgag gtgggacttt cttatttgtc gagcacttta gcttgatacg
     9481 ccgtgatagg agcgataatt attagctata aaatagagtg gttctctatc tgccatgact
     9541 acaaataagg ataatgatac ttctgaacgt tcaggctgcc agcgaaaaag gacagcgggt
     9601 gaaatgccca tgaatgattt aaccagtcat acccacggag gaaattatac atgttacaag
     9661 gaggaaaaag tttggaacaa tcagtaataa agtatactat gcaactatca atgcttaact
     9721 ttttatactc aagaaatatg ttatctaaaa atgagtatga caagattaga aacaaactgc
     9781 gtattaagta cacaaaatag ctgacttttt gatttgaatg cggtaatata gaatcaaaag
     9841 gaggaatttc agtatgaaaa aaaataatgt tgaaataata aaagctgatt ctttagttcg
     9901 tcgaagaggc gacaatgtag aaagacactt aaagagggtt gctgcttatt gcagagttag
     9961 ttccgatagt gaggatcaga aaaacagtta tgattctcaa gtaagacact acaaagaata
    10021 tatttctcag cgttcagatt gggagctggc agatatttat gcagatgaag gtatttcagg
    10081 aacacaagta ggaaagagac aagattttca acgattaatc aatgattgtg caaatggaga
    10141 gatagattat attgtcacaa aagcaattgc tagatttgca aggaataccc tagatacttt
    10201 gaagtatgtc agaatgttaa aggatatgca aattggagta tattttgagg aagaaaacat
    10261 agatacccta acaatggatg gagaattgct tctaactatt ctaagctccg ttgcacagca
    10321 agaagtagag aatacttctg cccatgtgaa aaaaggatta aaaatgaaga tgcaacgtgg
    10381 tgaattggtt ggttttcaag ggtgcttagg gtatgattat gatgtagaaa ccaagcagat
    10441 ttcaattaat aaaaaagaag ccaaaattgt tcgttatatt tttgaaaggt atctagaagg
    10501 tattggagga aaagtaattg caagggaact tgatgaactt ggttacaaat cgccaagagg
    10561 tttagaacac tggaatgata caacagttct aggaataata aagaatgaaa aatataaagg
    10621 tgatattcta atgggaaaaa cttttacagt tgacccaata agcaagagac ggttgagtaa
    10681 ttttggagaa gaagataagt actatatcaa ggataatcat gaaccaataa tatctaaaga
    10741 agattttgaa aaagctcagg agattagatt gcgtcgagca ggaaataaga agacagctgc
    10801 gaatgtaaat gggaagcgtg aacgctattc aaaaatgtat gcttttagta gcatgttgga
    10861 atgtggtttt tgtggttcaa tattatctag aagaagttgg cactgccgtt cagattatcg
    10921 caaagttgtg tggcactgtg ttacatcgat aaagaaagga aagaaatttt gtaagcatag
    10981 taaaggatta gaagagatcg ccattgaggg ggctttcctg gaagcttaca gacaagtcta
    11041 tcattcaaat gaaaatttaa tgacagactt acttgaaacg atagaatctg aattgaatga
    11101 caatagcctt aacaaggaac taaaaaggat tacaaacaaa cttcgaatat tactaaaaaa
    11161 agaggagaat cttgtaaatc taaggctcga aggaaaagtt agcgattcca tatacaatga
    11221 aaagtacaat gaaatttcct cagaaaaaga gtttctagca gaagagaagg taaatattga
    11281 aacaacatta aaatcagaaa tcgatgtaaa gaaaagacta actgagttta agcacttgct
    11341 atcttcgcaa aaaatgctta cggagtttga tcgtgcagtt tttgaaagta ttgttgagaa
    11401 aattattgta ggtggagtta atagcaacgg agaaattgat cctgcaatgt taaccataat
    11461 attcaaaaca ggtgaaattc aaaacaagga tggtaaacaa tttaaaagta aacgtaaaaa
    11521 tgctaaacta gaaacagata aattgtgtcc tcaaaacagt gacgaggata aaaaattgta
    11581 ttctcaagga acagacaaca cacgtggagt gtgtagtgtt gctggttcga tcttagccag
    11641 tcaataaaat gatatgtttt aaaaaaatta taatttcgaa acgtgaataa acttgtttaa
    11701 actttatgta tctttagaaa gtgtgttaac ttgaaagaac aaattttttt gatgggtggg
    11761 aatcc
//
LOCUS       DAVKUR010000057        10642 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKUR010000057 DAVKUR010000000
VERSION     DAVKUR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.057"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(429..679)
                     /locus_tag="VW749_001773"
                     /pseudo
     CDS             complement(429..679)
                     /locus_tag="VW749_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(672..788)
                     /locus_tag="VW749_001774"
     CDS             complement(672..788)
                     /locus_tag="VW749_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0175768.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(1003..1356)
                     /locus_tag="VW749_001775"
     CDS             complement(1003..1356)
                     /locus_tag="VW749_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0175769.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAQNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(1474..2442)
                     /locus_tag="VW749_001776"
     CDS             complement(1474..2442)
                     /locus_tag="VW749_001776"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0175770.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(2587..3147)
                     /locus_tag="VW749_001777"
     CDS             complement(2587..3147)
                     /locus_tag="VW749_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0175771.1"
                     /translation="MSNFLGSVHLLGVLFPDSTFLNAFESAIVAPLVEESLKLLPLVF
                     VLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIHTDLPEGFDFTISRILERIISGIAS
                     HWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAI
                     PVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(3153..4504)
                     /locus_tag="VW749_001778"
     CDS             complement(join(3153..4063,4063..4504))
                     /locus_tag="VW749_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0175772.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(4501..4845)
                     /locus_tag="VW749_001779"
     CDS             complement(4501..4845)
                     /locus_tag="VW749_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175773.1"
                     /translation="MYEEKQYFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDFMNCTPKV
                     RQKKSNFWGVLL"
     gene            complement(4866..5363)
                     /locus_tag="VW749_001780"
     CDS             complement(4866..5363)
                     /locus_tag="VW749_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0175774.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(5436..6797)
                     /gene="radA"
                     /locus_tag="VW749_001781"
     CDS             complement(5436..6797)
                     /gene="radA"
                     /locus_tag="VW749_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0175775.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(6811..7326)
                     /locus_tag="VW749_001782"
     CDS             complement(6811..7326)
                     /locus_tag="VW749_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0175776.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(7328..7771)
                     /locus_tag="VW749_001783"
     CDS             complement(7328..7771)
                     /locus_tag="VW749_001783"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0175777.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(7831..7924)
                     /gene="ffs"
                     /locus_tag="VW749_001784"
     ncRNA           complement(7831..7924)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VW749_001784"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(7957..8424)
                     /locus_tag="VW749_001785"
     CDS             complement(7957..8424)
                     /locus_tag="VW749_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0175778.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(8625..9911)
                     /locus_tag="VW749_001786"
     CDS             complement(8625..9911)
                     /locus_tag="VW749_001786"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0175779.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(10142..10378)
                     /locus_tag="VW749_001787"
     CDS             complement(10142..10378)
                     /locus_tag="VW749_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0175780.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         3287 a         2504 c         1733 g         3118 t
ORIGIN      
        1 tataaattaa tttgactttc ctgatagagt tgtttcacat cttatttcaa ctcactatag
       61 aaggaggaaa aggagggctg ggtggctaac ttcattatag aactttcaaa aagatgaaaa
      121 aatagcgtca aagaggcttt tttctcttta aaacaggaaa tttcaaagac aatcttgcga
      181 ctatccaaac tgtacgaata gcgagacata acttacttcg ctaatactat agtagattga
      241 aactagaata gtacacctcg atttctaaaa cattgttaga aatcgatttg actgtcctga
      301 acgatttgtc ctgttattat ttcattttac tatatcttat aaaaagatag aaatgtcaag
      361 caaaaatgac aagtattttg ataataaact tgccatccca tcaactttct actatataaa
      421 gtatgaactc atagcaagga ctcaaactca gccacggtca tgcctaattg ctcactcgca
      481 acctcaggtg ttagaagacc ttgacgtact agatttacta aacctacttt taatccctct
      541 tcaaggcctt cttctcgtcc ttgttcacaa ccctctgcac gaccacgttc aataccacgc
      601 tctagtcctt gttcaatacc ttcgcatagt cctgtgctaa caagacttgt tcttctcgca
      661 tatgtagttg actaaacatt ttcctgtcct cctcggacca gctcttgtag tccagcagtt
      721 gatttgcttg ggtaatggct cgttgcggtt gctgggtaaa gggcttgttg ccgaaaaact
      781 ccaaccatgg cttgcgaacc ttgtctttgc tggtttctct gtatttttta attccaagaa
      841 tgccatctta accagatggt tttcctgtcc attgttggta atcgccaata cctcacctgt
      901 tgtgtcttcg cgcatactaa cgctatgaaa agccaggcca tctgagaaat aattgctatc
      961 cacgatagca atgacgtaaa caggagcgat gtgtttgtag atctagtgag tatcaccttc
     1021 tcgctgacga attttttcaa gattttgatt aacctgactg cacaggtaag cccacaagtg
     1081 attgatgaaa aaattctgat gatggacttg aatctcaata attacttgag taccgttatc
     1141 caactccgcc aagacgtcta tactggtata aaaatcctgc accgagtaag gcatggagag
     1201 taatacgtga atattgctac cctccaaaat ggtcacattt tgggctggca aatccagcat
     1261 atcgcgaata aattgacaag taatttctgg attgctaaag attttcttag ctaccaagtc
     1321 attggttggg ctaatgcccg gatgacgtac agtcatattt cttctctttt tattatatca
     1381 cagttttaaa tctagcttta ctagattcac cgctactatc tatttattcg gaaaaaagac
     1441 gaaaaaacct gagaatcatc tcaggcttgg tcattaaatt tttttctcaa tatcgaaaag
     1501 tggagaaagt ggtcgttttt catgaatacg tacgatagca tcccctagga gatgagcgat
     1561 tgaaatctgc tcaatcttat caatcaaacg ctcttctggc agatagatgg tatccaaaac
     1621 aaccaatttc ttaatagctg atttttggat attgtccgta gcaggaccag aaagaactgg
     1681 gtgcgtacag cttgcataga cttcaacagc accagcttcc gcaagagcat ctgccgcatg
     1741 acaaatcgtt ccagcggtat caatcatatc atcaatcaag atacaagtct tgccttcaac
     1801 cttaccgatg atgttcataa cttcactagt attcatctta tcaacgctac gacgtttatc
     1861 aataatagcg atagaagttt tcaaaaattc tgccaactta cgagcacgag tcacccctcc
     1921 atggtccggg ctgacaacca catagtcaga accaaccata ccacgacgct caaaataatc
     1981 tgcaatcaga ggagcaccca tcaaatgatc cacaggaata tcaaagaatc cttgaatttg
     2041 cgcagcatgc aagtcgatgg tcaataaacg atccactcca gctacttcaa gcatatttgc
     2101 gacaagtttt gaagtgattg gctcacgcgc tctcgccttt ctatcctgac gtgcataccc
     2161 atagtaaggc atgacaacat tgacagattc tgcactcgca cgcttcaaag catctaccat
     2221 aatcaaaatt tcaagcagat tgtcatttac aggcgaacta gttgattgta ggataaagac
     2281 gtgtttccca cggattgatt cttcaatgtt gacctgaatc tctccatctg aaaattggcg
     2341 aacacttgat ttccccaact ctatcccaat ctcctgcgcc acacgttctg ccaattcttt
     2401 attagaagaa agggcaaata gctttaaatc agaaaaagac atgatttcct ccggtatata
     2461 tgtataactt gtgcttttca caagattttc catctaccat tgtagcgctt tttgcactat
     2521 ttttcaatca aaaataaaag aagggcacca tatttgtacc cttgcatcat tcttttgaaa
     2581 aatattctag gtcatcaact cattgtgttt ctcaacaaag caataagcat gataaaaacc
     2641 atagagagca atagccgtaa ccactggaat cgctaaaggc aactctgttt ccaactccac
     2701 aaaaggagag ttaaacaaga agtgagttcc caaggctaaa cctagaaaaa taaggccctg
     2761 tttcttgcca accttctgtc ctttataggc tctgtaaagc aagtaaacac ctactacagc
     2821 tagacctgaa aaagtccagt gagaggcaat tcctgagatg atacgctcta aaattcgcga
     2881 aatagtaaag tcaaagccct ctggcaaatc cgtatgaata taaccaatat cctcaatcat
     2941 ttggaatccc aaaccggaag caattccaag taaaaacaaa gattttaatt ttcgcacagg
     3001 aatcaaagcc aaaacaaaaa caagtggcaa taatttcaag gattcttcta ccaaaggagc
     3061 cacaatagca ctttcaaagg catttaaaaa tgtactatct gggaaaagaa cccccagtaa
     3121 atgtactgac cccaaaaagt tagacaaata atttatccaa aggatttagt tctgtactgc
     3181 acagaactaa gtccttttag ttttacctta attcgtttgt tgttgtagta atcaatgtag
     3241 tccacaatag cttgttcaag gttttctaaa gatctaaagt tcttctcata gccataaaac
     3301 atttcggatt ttaaaatgcc aaagaaagat tccatcatgc tgttgtctgg gctgttgccc
     3361 ttgcgtgaca tggatgcttg aattccctta ctctctagga accgatgata agaatcgtgt
     3421 tggtattgcc agccttggtc actatggaga atcgtattct catagtattt ctctgtaaag
     3481 gcctgttcta acatactctt cacttgttct aagtttggcg aagtagaaag atgataagca
     3541 atgatttcac tgttaaaacc atctaaaact ggtgataaat agagtttctg tgtgctattt
     3601 ggaatggcaa actctgtcac atctgtatag cacttttcca ttggcctcga tgcttcgaac
     3661 tggcgttgaa tgagattctc tgctttcttg ccaatctctc cttggtagga agaatacttc
     3721 cgtttacggc gaattcgagc cgttaaacca agaattctca tcaaccgttg aactttctta
     3781 tgattgacca caaaaccacg attccttagt tctaaatgga ttcgacgata gccatagttg
     3841 cctttatgtt cattatcaat gccctgaatt tcggttttaa tctctttatc tttatcaacc
     3901 ccatccagtt gtttcaactg ataatagtaa gtcgagcgag ctaaacgtgc tgtttcaaga
     3961 agaaaatcta gtcgaaatcc tcctgaaacc atttctctaa ctgtctctgc ctttctcgct
     4021 ctagggcttc gtccctttcc tctaactctt ttaacttttt taggtaggcc acctcagtcc
     4081 gtaagcgttc attctcctcc tggagtcgtt ctagttctgt catttcttcc caagtcttct
     4141 tccgtttacg tcccatttta gctggtctcc ctcttgtttt ctcaacaata gtatacccgt
     4201 ttttcttgta ttgtgccggc caaaatgaaa gcattccttg gtttgggagg gcataatcaa
     4261 gactaatact tctttgtgaa caaccttcca gtaaggcttt atccatcatt tcttgtttca
     4321 atttagaaga atagtgacga ttcttccctt ttttaacgat ttctatgcca taacggtcaa
     4381 ttaatttcac catgtacttt agaccagaaa catccacacc aaatcttttt gaaagctgtt
     4441 tgaagctttg tccttgcttt cttagttcat agatctgaac tttatcttca taactcaatt
     4501 tcataataaa acaccccaaa agttagattt tttctgtcta acttttgggg tgcagttcat
     4561 aaaatcatgg atataagtat tagcaaaact agacaaccag cctgaaagga acatccctcc
     4621 caataaagac agaatcaaaa ccttctttgg caattcccat tttttcccaa tacggaagag
     4681 aaaataaaga gccggaatca tgtaaaagag agctagaaag atagaaactc ccattagtcc
     4741 atattccgca cctgacctcg aaccgtccgt atagtagatg gtttcatact gtaaaccaat
     4801 acatagcaat aaaataaaaa taaaatactg cttttcttca tacactttct ttctaaatga
     4861 agtatttata attctacgac tgtcatactt cctgtatcaa cattgtaaat agcaccagag
     4921 ataatgacat cgtctggtat taggggagac tcgataagca gttgcatatc ctcgcgtaca
     4981 ctctcttcta tatcttggaa gggcaagaag tcctggtctg acacatctac acctaattcc
     5041 tcttttaaat actcctgaaa aggttcattt tcaaaggtct gagcaccaca gtctgtatgg
     5101 tgcaatacca caatctctct tgtccccatt tgttgctggg aaataactag cgaacgaatc
     5161 atgtcttcag tcactcgacc acctgcattc cgcaagatat gagcatcccc aagtgccaaa
     5221 cctagagctt gcgcaacgtg caaacgtgag tccatacagg tcacaatagc tactcttgtt
     5281 ttgggtttaa gtggcagatt taactgccca tgtagggcaa cataagcctg attagcttgc
     5341 ataaactgtt caaaatacga cacgattccc tccttgaaaa tttgatagtc aaatatttct
     5401 cctatcttat catttttaag agaatttgtc acggattatg caaagacctt tttcaaaact
     5461 tcctgaatcg ttgtcacgcc aatgacctga atttccttag gcagagtgat tcctgtcaag
     5521 gaattcttag gtacataaat cttagtaaag cccagtttag cagcttcgtt gatgcgttgc
     5581 tcaatacgat tcacgcgccg aatctctcct gtcaagccca gttctccgac aaaacattcc
     5641 tgaggattag ttggcttgtc tttgtagctc gaagcaatag caactgcaac agccaagtca
     5701 atggcaggtt catccaattt aacaccacca gcagatttga gataggcatc ctgattttgc
     5761 aagagaagcc ctgcccgttt ttccaaaaca gccataatca agctagcacg gttaaaatca
     5821 agtcctgtcg tagtacgctt ggcatttcca aacatggtcg gtgttaccaa agcctgaacc
     5881 tccgccaaaa tcggacgcgt cccttccatg gttacaacga tggaggaacc agttgcccca
     5941 tccaaacgct cttctaggaa aacttgactc ggattgagta cctcaaccaa gccgcccgac
     6001 tgcatctcaa aaatcccaat ctcattagtg gaaccaaaac gatttttgac cgctctcaaa
     6061 atacgaaagg tgtggtgacg ctccccttca aagtaaagca ccgtatccac catatgctcc
     6121 aacatacgag gcccagccaa ggttccttct ttggtcacat gacctacgat aaagatggca
     6181 atgttattgg tcttggccaa ctgcatgagt tcagcggtca cttcacgtac ctgagaaaca
     6241 gacccctgca cccctgaaat ctcaggagac atgatggtct ggatggaatc aataataaga
     6301 aagtctggct ggatacgctc cacttctgca cgaacactct gcatattggt ctctgcatag
     6361 agataaaact cactatcaat atcacctaag cgctctgcac gtagtttaat ctgctgggca
     6421 gactcctccc cactgatata gagaactgtc cccacttggg acaactgggt tgagacttgt
     6481 aggagaagag ttgatttccc aatcccagga tccccaccga tgaggacgag acttcctggt
     6541 accactccgc ctccaagcac acggttgaat tcctccatct ccgtcttggt tcgattgaca
     6601 ttgatggaag tcacctcagc tagtttcatg ggcttggttt tctcacctgt caaggacaca
     6661 cgcgcattct tgacctcggc aacctcaacc tcttccacaa aagaagacca agacccacag
     6721 ttggggcaac gtcccagata tttaggggaa ttatacccac aattttgaca tacaaatgtc
     6781 gcttttttct ttgcgatgac aaacctcttt ctatatctct aactcacact caatcacttg
     6841 gcaaaaatca atcttctcat ttggcacaaa ctggcgcatg agcattcgat gagcaacaac
     6901 taccacagtc tgatgttctc gatacttaga catacattct agaaaccgag acttcatttc
     6961 cgtagctgtc tcatattgaa taggactatt aggaagcaac tcccccttgt tttctaaaaa
     7021 cagtcttcta gctgtttcaa agttttctat tcctgtttta tagacctgcc attcatgtaa
     7081 taaaggctct actcttaaag gaagacccgt agcacagacc acatacgaag ccgtttctaa
     7141 agctcttgtg actgcagaag atacgattat ttcagctgac gagagtaaag gagttttgct
     7201 caatttctgg acttgctgcc gtcccatctc agacaagggt gccaaatcta tcccaaatcc
     7261 tatataagaa cgctcctcta actcacggta atctggctcc ccatgacgta caaagataat
     7321 cttcattcta gtgccctgtc gatccaaatc caccagttcg aacgccatca gctgcatctc
     7381 catctgcaat taagaaagta gcaaaaacag cctggacaat acgttcccca acttcaagaa
     7441 caacctcttg gtctgtgata ttcttcatct gcgcaaaaat atgcccttca tttccaggat
     7501 ttccataata atccccatca atgaccccaa ctgagttaat taaaaccaag cccttcttac
     7561 gaggatttga agaacgatca tagaggtaga gaacctcagt cggctgcata taagccttaa
     7621 cccctgtcgg aaccaagaca atctctcctg gcgcaacaac tgtacgcaca gcaaccttta
     7681 agtcgtaacc agccgcatgc gctgtctcac gcttgggcaa taaattttca tctgtaaaac
     7741 tcgaaaccaa ttcaaaacca cgaattttca taattttctc ttttctatta tcatttattc
     7801 tagattattc tatcttattt attcggaaaa agcacgaaaa aagagcacac aattcaaatc
     7861 gcttagggct gctggattcc tcccctgacc cgcttcacgc agaactgttg ctccactatt
     7921 tattatatca cattcctatt cattttaaaa gcaaaattat tttttccgtc tatttctaaa
     7981 aaaatcctgc atgatagctg cgcattcatc ttccaaaatt cctatttcaa cctccacacg
     8041 atgattgaga cgctcatctg tcaagatatt gtacaaactc ccagcagcgc caaatttctg
     8101 gtttttagcc ccatagacca catttggaat gcgggcaagc ccaatcgctc cactacacat
     8161 gacacaaggt tcaatggtca caaaaagtgt gcaatccagc aagcgccagc tctcctcact
     8221 caagttcgca tcctctatag ccataatttc cgcatgcata accgctcgct gtaattcctc
     8281 acgcgcatta tgcccacgac caatgatttc cccatctttg acaatcacac aaccaattgg
     8341 aatttcatcg tgttcaagag caatctcagc ctctctcaaa gcctccctca taaagacttc
     8401 tttttcttca agcgtataat acatctcttt tctcttttcc tacttatcga ttttattatt
     8461 atatcatgaa tcccaacaca aaagaagcca ccgaatgcgg tgactctata gggagattat
     8521 tatgaaaaag aaaagtttag gatatttgtt acaacaagtt aggaggtctt cttgtaaccg
     8581 tctatagtat acccgaccta tcttaaacaa atcttaaaaa tctcttagga ccaaacactt
     8641 tctaaaatat ttgtttgttc acgaccagga cctactgaga aagtagaaat acgaacgcca
     8701 accaattcac tcacacgacg aacatagtta cgcgcattct caggaagatc ttccaaattg
     8761 cgaactccgg taatatcttc tgaccaacct ggcaactctt catagatagg cttgcaacgt
     8821 ttcaattgct caagactagc tggatagtag tcaatacgtt gaccgtcaag atcataggcc
     8881 acacagattt tcacagtatc caaaccgctc aaaacatcaa tagagttcaa agaaaggtta
     8941 gtaataccag aaacacgacg gctatgacgc atcacaactg agtcaaacca acctacacga
     9001 cgtggacgac cagttgttgt accatattca tgacccactt cacggatacg ttctcccact
     9061 tcatcaaaca actcagttgg gaaaggacca tctcctacac gactcgtata agctttacat
     9121 acacctacaa ccttgtcaat cttgcttgga ccgacaccag aaccaattgt cacaccacca
     9181 gctacagggt ttgatgacgt aacaaatgga taagtacctt ggtcgatatc tagcataaca
     9241 ccttgtgcac cttcaaaaag cacacgtttg ccattatcaa gcgcatcatt caagataaca
     9301 gatgtatcta tcacgtattt cttgatttgt tgaccatatt cgtaatattc ttcaaaaata
     9361 tcatcgaaaa caatcgcttt actgtcatac aatttttcaa aaagacgatt cttttcagca
     9421 aggttacgtt ctaaacgctc acggaaaata tctttatcta aaagatctgc aatacgaatt
     9481 ccaacacgag cagccttgtc catataagct ggaccaattc ccttaattgt cgtaccaatc
     9541 ttattgtcgc ccttagcttc ttcttgcaag cgatccaact cgatatgata aggcaaaata
     9601 acatgcgcac gatcagaaat acgcaagtta tcagttgtta caccttcctc atgaagatag
     9661 ctcaactctt ttacaagaga tttaggattt acaaccatac cattcccaat gacagatatt
     9721 ttttcaggga agaaaatccc agatggaatc aagtgcaact taaatttctt accgtcaatc
     9781 acaatcgtgt gaccagcatt atcaccacct tggtaacgtg caattacttc tgcattcgct
     9841 gaaaggaagt ctgtaatctt ccctttacct tcatcacccc attgggtacc tacaacaaca
     9901 actgaagtca taattttgtc tgagccctca ggctcttcct ttctcacata catggcagga
     9961 ctctcacctg caattatatc ttacaattta ttataataaa aaatcgcctt tttatcaaga
    10021 agaaacaata gaaagatttg ctatttccaa ctattaaaaa atgatttaga aaaattacta
    10081 gctatttact attatctttc cataaaagag taaattagtt cggaaattta ctaaaattac
    10141 ctcaacaaga aataaacccc cgattcatta ccaatttttc aagatacaaa cgataagcaa
    10201 cacgataatg gtaaacgata aaatccctac gacaaccaat gccatatctc actaaataat
    10261 aaattaaaaa tttaaaatga acatgttccc agtcaaaatt atcaccaaat gtaggaccat
    10321 actcttcttc aatactatca tagaaattag ccatctgctc ataaattttt tgtaacataa
    10381 tcaaatactc cttttctttt ttataaactt attctaacaa aaaattttac acattcacta
    10441 tcaattcctg aattgttaaa ataccagcct caacaagata aaaataggaa aagttgacaa
    10501 aatagaaaca aatttgctac ctaaatttca aacaattaaa gttctaaaaa gaccgcctta
    10561 aaacttttgg gtaaatccta ttaaaactat aatattttta tataggtatt atggttctga
    10621 ttttctagta taaaaaaatt ca
//
LOCUS       DAVKUR010000058        10552 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKUR010000058 DAVKUR010000000
VERSION     DAVKUR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.058"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(63..1487)
                     /locus_tag="VW749_001788"
     CDS             complement(63..1487)
                     /locus_tag="VW749_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0175781.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2032..4311)
                     /gene="pulA"
                     /locus_tag="VW749_001789"
     CDS             complement(2032..4311)
                     /gene="pulA"
                     /locus_tag="VW749_001789"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0175782.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPYGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4423..6381)
                     /gene="ligA"
                     /locus_tag="VW749_001790"
     CDS             complement(4423..6381)
                     /gene="ligA"
                     /locus_tag="VW749_001790"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0175783.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERGNLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6474..7652)
                     /locus_tag="VW749_001791"
     CDS             complement(6474..7652)
                     /locus_tag="VW749_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0175784.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGFIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSIHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7732..8595)
                     /locus_tag="VW749_001792"
     CDS             complement(7732..8595)
                     /locus_tag="VW749_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0175785.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYFFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8598..10499)
                     /locus_tag="VW749_001793"
     CDS             complement(8598..10499)
                     /locus_tag="VW749_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0175786.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSKKTSGNVVLTVENTAI
                     GYDGEVLSQPINVDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3164 a         2335 c         1893 g         3160 t
ORIGIN      
        1 taattattat tattttatag caaaaaaata aaaccaggaa aacaatttcc tgattttaca
       61 cgttatttca catcaaaaac aatggatttg acatttgtca tcgcttcaat gctatattta
      121 attccttgca ctccagctcc agaacctttg acaccaagga atgggaaatt atctggacca
      181 cgctgggttt tattattaat gtggactgta cctacttcaa gtttttcagc aatttcaaag
      241 gcttttttga aatcatttgt aaagactgat gattgaaggc cgaattcaga ttcgttggca
      301 aaggcaatag cttcctctac actagccaca cgaatgattg gtaaaacagg accaaatggc
      361 tcttcccatg ccactttcat atcttttgta acttggtcaa aaagcactgg ccagaggaga
      421 ttgccctcac gtttgattgg tgtaagagcc tgagcctctt tttcttgtgc atcctcaatc
      481 aagccccaaa tgaagtcggc tgaagcattg tcaataacag gtgtaatatc agcattgtca
      541 aatggatcac caactgttaa tttagaaact tcttcctgaa gcaaagtagc taatttctct
      601 gctacacttt cgagaacaat gacacgttta atggccgtgc aacgttgtcc tgagtagcta
      661 aaggctcccg caacaatttg cttggcagca tgttccaaat ctgcatcttc tagtacaaga
      721 gctgcatctt tcccaccaag ttccaacatg ataggacgca taccagctaa acgaccaata
      781 cgttctccaa taggagttga acctgtaaag ttgatgaagt tgacttcttt gtgctcaatg
      841 atataatccc caatttctga accacgacct gtaatggtgt tgaaaacacc tgccggaatc
      901 cctgcttctt caaatgcttt agccaacaag agtccagaaa tggaaccttg tgttggtggc
      961 ttaaacatga ccacattccc tgcaatcaag gcaggtgcaa ttttagaagc agataaatta
     1021 actggataat taaagggagc aatcgctagc acgataccaa ctggttcacg acggacaaca
     1081 gccagtttgt ttttacttgc tgcctcaaaa ccaccacctt ccattgcttg tccagtgata
     1141 cggagacctt cctcagcagc ataacgaatc aagtctgctg tacgcactac ttctccaatt
     1201 gctgctttaa tcccttttgc tacttctttg gcaaggatag taccaatttc ttccttatcg
     1261 cgttctaaaa tagctgctgt tttatgtaaa taagccgcac gttcaactgc tgataaagct
     1321 cgccatgctg gcagggctgc acgcgcagct tgcatagcct catcagcttc agtctgagtc
     1381 atggctggaa ctgtacccaa ttcttcttga ttgattggtg aataaatcgt aatttcttgt
     1441 tcagatgatt tccattttcc atttactaaa ttctgatatc ttgtcaaatt cttgtcctcc
     1501 tgaaaatgat taagatatat tttaccaaat tttcagaaaa tcacaaccct ttttgcaaaa
     1561 tttttgagat tattttcaca aacttgattt ttcaaagtat actcaataaa aataaaaaaa
     1621 atccactacg tcaaggcgag gctaatgtgg tttgaagaaa ttttcgaaga gcgtgaatga
     1681 gtatcatcta tagtaaaata aaaaaactga acaatttggt tggggacagc caaaccaatt
     1741 tctcacaatg tttcagaaac aagggtgtgc tactccaatt tcagcctact ataactgtca
     1801 tagattgctg aaacaaagtc taggtaaaag tcttcataat aaaaagacct cctatcaagt
     1861 gttcaaaaac tttgatagga ggtcttgttt tgtgaaaata tttatcaaat tttctataca
     1921 agtgagctgt tagccaggtt ctttctattc tttcaatttc aatgaatgga ttttttacta
     1981 atactcataa ctgggaattt gtctgtgtaa aaatagcgag atagatggta tttataaaac
     2041 actcaagaca gctagactaa tatcatttaa aacattatct tcttttgagc gactgttggt
     2101 taccaacata gctaaatttc ctgcattttc aaattgatag ggttctgatt tagcattcac
     2161 aaccaccaag aggtgttctt tgccgtgaac ttcatagata aggtagccgc tatgttcaat
     2221 cgcagaatgc acaaagacat gatggtaaat ttcatcatag ctagagtaag aaaaggcacc
     2281 agtttttgtc ttcaatcgga tgacttgacg gataaactca atactgtctt gacgctcatt
     2341 aatcaagttc cagttcactt ggttcacact gtcaggagca ttatagctat tcatcgcacg
     2401 ctctctatca tcatgggtca actcaccatt ttcaccagtc gcaaccagtt tggtacgacc
     2461 aaattcttga ccgatttcca taaaggccat cccctgcatg agcagattca tggctgtggc
     2521 agtttcgacc ttgcgcatga tttgctctga actttggtct ggatgaaggg ttgccaataa
     2581 atcgtgaaga ttgtaattgt catgggcttc tacatagtta agcacctgat ttggatgtgt
     2641 atagcttcct aattcacgac ttcctaggat tgctttagct agaattggct ctgtcgcagc
     2701 accactgaca aaacctgact tgatagcacc ataaacttct ccccctttga cagcatcgcg
     2761 ctgattgtca ttaaagaaac caatatttgg catctggtag gcattgtcct tcttggcctt
     2821 atcataaggg gcaagacctg ttcccatatc ccatccttct ccatagagga taatgttgga
     2881 gtcgatttca tccaagcttt gacgaatcat ctgcatggtc ttgacatcat gaatccccat
     2941 caagtcaaaa cggaagccgt caatattata ttcctgcacc cagtatagaa gagaatcaat
     3001 catatacttg cgaaacattt cgtgttcact ggctgtttca tttccaacac ccgttccatt
     3061 ctggaaggta ccatatggat tcatacgata atagtaatca gggactgttg tttggaatgg
     3121 tgcatcaaca actgagaagg tatggttata gactacatcc ataatgactc caatacccgc
     3181 atcgtgataa gcttgaacca tcaccttcaa atcacgaatg acctgagctg gatcatctgg
     3241 attagttgaa aaactagttt ctggcgcgtt atagttttgt ggatcataac cccagttgta
     3301 ggttacattt ccatcctcat cgtattcttt atgacggtct gcaattggtt gcaattgaac
     3361 ataattgtag cccagcttct tgatgtaatc aaaagcagtt gactggccgt attggttaac
     3421 tgttccagcc tgagcagcac ccaagaaagt tcctcgaaga tgttcatcta cacccgatgt
     3481 aggtgattta gtcaaatcac gaatatgcat ttcacagata actgccttac atggattttc
     3541 caagcgccaa gtagcctccg aaccgtgctt aacctcgaag ttttcaactt gcttttctac
     3601 atggctcaga atagctgaac gtttgccatc agggctggtc gcgattgtat aaggatcacg
     3661 tgtcagtgtt tggtgatgag ggaattggac ttgatactga taagccttac ctaccaaatc
     3721 ttcctcaaca tccaaactcc agacaccgat tgtattgtcc ttatgattat aagagtagct
     3781 attgcctctt ttcatctcaa aagtcttcca aacgggtgca tcattagcag ctgattcata
     3841 aacgacaact tgcacttctg tcgctgtagg tgaccagagg gaaaaatgag cctgattgtc
     3901 ctctacacgg caacccaatt ctccttggta accccaatga tggtcaaaac tagcactgtt
     3961 aatggcctta tcaaaggcaa aaggattttg atttttatag aaaggactgg caatagcagg
     4021 attttcagag taataaatcc tatcatcgcc ttccaaaatc cagacctctg ttaatagggg
     4081 atagtgatta aaacggatag aatattcttt actagtttga cctgtatgaa ccacaaaatt
     4141 caagctttct ataacatgtg aacttgggtg ttcaaagcta aataaagctc caaaataatc
     4201 ttctttgtag gttagcaaat caattcgttg atcctgactt tttacaaagg agcaagtgtc
     4261 atattctcca ttcttacgat ggtaatgaat gcgcataggg tagttataca ttttttattt
     4321 ttccttttta ctttgtttct atttcactaa taaatttttg tcaatctcgt ctcaattaac
     4381 agacatagtc atattctcta aactctgttt ttaaacgatc cattacaaac tttctagcca
     4441 tgcctcatct ctgacctgga taccaagttc ttgtgctttt tgcagtttac ttccagcgtc
     4501 tgcacctacc acgacgaggt cggtcttttt agaaacacta cctgtcactt tggcacccag
     4561 actttcgagt ttacttttag cttctgagcg cttgagtcgt tccaattttc ctgtcaatac
     4621 cacggtcaaa cctgacaagg ccgcatccgc tactaccgtc tgtcctttat agtccagatt
     4681 gaccccagtt tctttcaatt ctctgagcag aatttcagag ccttctgtcg caaaataagt
     4741 ctgaagactt ttggcaatca cgccacctag actttcaata ctagccactt cctctgaatc
     4801 tgcctgatac agattttcaa ttgaatggaa atattgaagt aaaagctgac tagccttgct
     4861 tccgacatga cgaattccca aaccaaataa gagcttctcg gcagaatttt cctttgatgc
     4921 ttggatagcc tgatacagtt tagcagcgga cttttcctta accccctcta aaaggaggaa
     4981 atcctcttct tgcaaacgat aaatatccgc cacatccttg actaaattag cagcaaaaag
     5041 cttctcaaca atagatggac caaggcctgt aatattcata gcatcacgag aagcaaagtg
     5101 aatcaagcct tccatgattt gagcagggca acgcggattg atacaacgta gggccacttc
     5161 atcttcaaag tgcaacaagt cagagttaca acttggacag tttgtaggga tatctagttt
     5221 ttcttcagaa acccgtttgg actctaccac acgtaaaacg gcagggatga tgtcaccagc
     5281 cttatataca atgaccgtat cgtcttttcg gatatctttt tcagcaatat aatctacatt
     5341 gtgcagggtc gcacggctaa cagtcgtacc ggcaagttgt actggtgtta gattagcagt
     5401 tggagttaca acaccggtac ggccaactgt ccagtcaact gataagagtt gagcttcttt
     5461 ttcttcagca gggaacttgt aggctactgc ccactttgga gccttaacgg taaaaccaag
     5521 ttcttcttga cttgctaggt cgttgacctt gattaccact ccatcaatat cgtaaggcag
     5581 atttccccgt tcctgtccta cttcttggat aaaattccag atttcatcta tgttttcagc
     5641 caagattcgc ttaggattga ccacaaaacc tagttgttct aggtacttca aacccttttc
     5701 ttggctatca cgagttgaag ggctggcttc ttgatagaga aacgttgcaa gattacgctt
     5761 ggcaactact gctgtatcca actgacgcag agttcctgct gccgcattac gaggattagc
     5821 aaattcaggc tctccatttt cttggcgcac ttggttaact tggtcaaagg aagcgcgtgg
     5881 catgtaacat tccccacgaa ctgtgatatc tagttcttct ggcaaagtca aagggatgtc
     5941 cttaacacgc ttgaggtttt ctgtgatatt ttcaccaatt gaaccatctc cacgtgttac
     6001 cccagcaacc aaaatcccct tttcataagt cagcgagata gataagccat cgattttcag
     6061 ctcacaaata taggtcggat gagccacttc cttacgaaca cgcgcatcaa aagcatctag
     6121 ctcctcacgt gaaaaagcat cctgcaaact ataaagagga tactgatgac tgtatttttc
     6181 aaaaccatct aaaaccttgc caccaacacg atgagtcgga ctgtctgcta gcacttgctc
     6241 tggataagca gtttctaact cgaccaactc acggtaaagg cggtcatact cactgtctga
     6301 aaccgaggga ttatcgctgg tatagtactc agtcgcatag cgattgagca aagcgactaa
     6361 ctcattcatt cttttattca taagaccatt ttaccataaa acaagccctc ctcacaaacg
     6421 agaagggcgg aaaaaacact tagtttgaaa ttatttttga aactcaagca accttatatc
     6481 aatttttcaa aatgagttcg aacataaata aacgatatac aagacaagat gataacacca
     6541 cttccaatta tcaggaaaga agagagatgt atacttggca agactgtcat aaatcctttt
     6601 gcaataggca taaatagaat agctaaggta aaaattgtac tcagtactct tccaagaaat
     6661 tcgctctcaa ccttggtttg tacttgagta aaaaagtgaa tattaaaaat cgtcataaac
     6721 aattcacaaa ctaaatttcc agaaaaggaa agaaaagttg gaagtggtaa tcccatcata
     6781 aaaactccga cacctgtcaa agccagtaaa atcaaaagat tataaatatt agctttaatt
     6841 ttactagcta gaagagcccc aatgatgaaa ccaatagccc ccatagttaa aatacttgca
     6901 taggctcctt ctgacccgta aagctgattc gaaaagggaa gtagaaattc aaaagctgca
     6961 aaaaagaaat taacgctgga agctaccagc aaaaggaaga aaatttcttg ctgatgccag
     7021 atatagtgta acccatcctt gatatctaca aaaatatctc tcccagtaaa agcctttttc
     7081 tcttgaactt ttgcttcctc ttttggaagg aaagccacta gaacaaaagc aatgaaaaaa
     7141 gtcagcgagt ctagcagtag cgtcatatgg agacttgcaa actgtaaaac aaggaaggaa
     7201 agaacaggag agctaacacc tacaacctgc aaaaccagct ctaagcgaga attatagatc
     7261 acaatctcat ctttctccac cacttcagtt atgatagctt tattggctgt gcgagaaaag
     7321 gcaaaagcaa tagcctgcac aatgttagca acaatcaaag cgccaatcat ccagctatca
     7381 ttccttatga aagaaatagc cagacaaaga atcccacaaa caagatctgc cgtcattaaa
     7441 atcttacgac gagaaaaacg gtctgaaata actccgccaa agggattgac gagaatagat
     7501 gtgacgagct cagaaatctg atacattcct aaaactgtct gtcctatagt ccccatagaa
     7561 gccaaccaga cactatttcc ataatcatag agcatatttc ccattttatt gatagcccca
     7621 cggctaatca actgcactgc atagcgattc atattaaagc tcctctcaaa ttttgaaact
     7681 attgtatcaa aaccgaaagg agctttttat tttttccctt atttgggaaa attaactttt
     7741 gacaaatttt tcgtagtgtt cctgataata ggctacttgc tctggaagac ctaacacatc
     7801 aaaaatatgt atggcctctt gcatctgctt acagccttct ttacactgtc ctttttgata
     7861 taaggcaaaa ccttttaaat aatggaaaac attacgctca taaagcttaa tacctttgtc
     7921 aataatcttc tctgtataag cctcaaaata gttggcatta taaaaagaag aatgctctaa
     7981 acaatgctgg taacaattga gggccaaaat caaaactaat ctcttatggc gactaatctc
     8041 ttggtaaaat tcctccctct ccataacttc tctaccaatc cgagtgacat agtctacatc
     8101 gtagaaacta tagaggttac cgaaaagaat caactcatac atggtccatt cttctgtttt
     8161 gaagaaataa tctgctacct tatccaaatc atcctgcttc atatcataac tcgcatctct
     8221 ttgacaaatc agaccttgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga
     8281 actcttagac ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga
     8341 atagtaaagt gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct
     8401 tgccttatcc atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg
     8461 ggagactgcc aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga
     8521 ttcgcctgct gcttccttta aagaataatt tccacttgtt cgaaattcac gaaatacttt
     8581 tccaagatgt tccatcttta cacctgatct gataattctt cccactcaag catagcttct
     8641 tcctgacgat ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg
     8701 tttgtttcca acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca
     8761 gcttctagac tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg
     8821 gcctgatagt cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca
     8881 gtctgactca tttctgctgt tgctctcttc tcaatatagt agtcgtaatc tccaaggtag
     8941 agagttgaac cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa
     9001 cgatcatgac tgacaaaaag caaggtacca tcaaagtcaa tcaaggcatt ttctagcact
     9061 tccttactat caatatccaa gtggttggtc ggctcatcca gaatcaaaaa gttattgttt
     9121 tccatagaca atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact
     9181 gattttttaa catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact
     9241 tctggtgtca gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc
     9301 ttgctttggg tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttctccc
     9361 ttgataaaag gaatctggtc cacaatagac ttgataaagg ttgacttgcc gataccattt
     9421 ggaccaacga tagcgacagc attcatctta cgaagatcta cgttaatcgg ttgtgacagg
     9481 acttccccgt cataaccaat agcagtattt tcaacagtca aaacaacatt gcccgacgtt
     9541 tttttagact ggaaggtcat gttggctgct ttcttgccag cttcaggctt gtccaaacgc
     9601 tccatttttt ctagttgttt acggcgagat tgagcacgtt tagtcgttga agcacgaact
     9661 agattgcgat tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt
     9721 tttgcctcag tagctagctt ttgctccttc aattcgacaa aacgagagta attccccaca
     9781 tagcgatcca aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa
     9841 taacggtcgt ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc
     9901 caggcgatgg tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc
     9961 ttttcaagga gcattttagc tagagccaaa cgagtatttt gaccacctga aagttcagct
    10021 attttcatct gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca
    10081 gcttcatagg taaagccgcc tgcttggcga aaattctcag ataagtggtc gtaatctgac
    10141 atcagtttat ccaattcatc gccagacttt tcacccatct ccaactccat ctgacgaagt
    10201 tgtttatctg tccgacgtaa gtcatcaaag acatgaagca tctcatcata gatggtattt
    10261 tcagactcaa aacggctatc ttgagctagg taagacagag aaatatcttt tttcttattg
    10321 atttctccac tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct
    10381 gcaccatttt tcccaacaag ggcaatccga tctcgttcat caacctgcag gttgatatta
    10441 tcgaaaagaa cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aataatcata
    10501 caagtagtat agcatgtttc cctaagtcat tcaagataat cgtaagtctt tt
//
LOCUS       DAVKUR010000059        10428 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKUR010000059 DAVKUR010000000
VERSION     DAVKUR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.059"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(374..766)
                     /gene="rpsI"
                     /locus_tag="VW749_001794"
     CDS             complement(374..766)
                     /gene="rpsI"
                     /locus_tag="VW749_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0175787.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(785..1231)
                     /gene="rplM"
                     /locus_tag="VW749_001795"
     CDS             complement(785..1231)
                     /gene="rplM"
                     /locus_tag="VW749_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0175788.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            1588..1905
                     /locus_tag="VW749_001796"
     CDS             1588..1905
                     /locus_tag="VW749_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0175789.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(2056..2868)
                     /gene="folK"
                     /locus_tag="VW749_001797"
     CDS             complement(2056..2868)
                     /gene="folK"
                     /locus_tag="VW749_001797"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0175790.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2911..3465)
                     /gene="folE"
                     /locus_tag="VW749_001798"
     CDS             complement(2911..3465)
                     /gene="folE"
                     /locus_tag="VW749_001798"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0175791.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3446..4768)
                     /locus_tag="VW749_001799"
     CDS             complement(3446..4768)
                     /locus_tag="VW749_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0175792.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLESIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEEKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGCFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4770..5714)
                     /gene="folP"
                     /locus_tag="VW749_001800"
     CDS             complement(4770..5714)
                     /gene="folP"
                     /locus_tag="VW749_001800"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0175793.1"
                     /translation="MSSKANHAKTAICGIINVTPDSFSDGGQFFALEQALQQARKLIA
                     EGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAAL
                     AAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQTF
                     TEKELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLR
                     DLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQ
                     GVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5839..6546)
                     /locus_tag="VW749_001801"
     CDS             complement(5839..6546)
                     /locus_tag="VW749_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0175794.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6599..8017)
                     /locus_tag="VW749_001802"
     CDS             complement(6599..8017)
                     /locus_tag="VW749_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0175795.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTKVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8207..9019
                     /locus_tag="VW749_001803"
     CDS             8207..9019
                     /locus_tag="VW749_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0175796.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9358..10377
                     /gene="adhP"
                     /locus_tag="VW749_001804"
     CDS             9358..10377
                     /gene="adhP"
                     /locus_tag="VW749_001804"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0175797.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         3070 a         2357 c         2026 g         2975 t
ORIGIN      
        1 gcccaaactc ctcgcataaa agttctaact tacccattct atggaatctt gcattatcca
       61 taatatagta gattgaaact agaatagtac acctctactt ctaaaacatt gttagaattc
      121 gatttgatta tcctcggttt gtcctattct tatttcacct tactataaaa ataaggtaaa
      181 cttttgagtg ctttgaaaca ttgatataat cgtattgatt aacgttttga ggcaactgac
      241 cttgtcaggt tgcagccaca tttgtaagcg actaaagtcg caacaactgt gtcaattgca
      301 ccaatttagt aagaaagtat aaaaaaagaa caccccgaaa ggtgctctgt ataagtatag
      361 taattctttc gaattaacgt ttactaaatt gtgatgcttt acgagctttc ttaagacctg
      421 gtttcttacg ttcaacttta cgtgagtcac gtgtaagaag tcctgcgcgt ttcaatgaat
      481 cgcggaagtc tgggtctact tgaagaaggg cacgagcgat accgtgacgg atagctcctg
      541 attgaccagc gtatccacca cctacaacgt taacgaaaac gtcgtatgaa cctacagttg
      601 aagtaactgc gaatggttgg ttgatgacaa gacgaaggtc agcgtgtggg atgtactctt
      661 caacatcttt tttgttaaca gtgattttac cagttcctgg aacaaggcga acgcgtgcaa
      721 cagcgttttt acgacgtcca gtacctgcat attgtgcttg tgacatactt tattgttcct
      781 ttccttagat aagttctgaa atgtcaagaa cttctggttg ttgtgcagcg tgagtgtgct
      841 cagctccaac aaatactttc aacttcatac cttgagcgcg tccaagtgta ttgtgtggaa
      901 gcataccttt aactgatttc tcaatcaaac gtactgcatt tttagaacga agttcacctg
      961 cagagatttg tttcaatcca cctgggtggt ttgagtgagt gtagtagatt ttatcagttg
     1021 cttttttacc agtcaattta actttttcag cattgataac aatcacgaag tcacctgtat
     1081 cagtgtgtgg tgtaaatgtt ggtttgtttt ttccgcgaag tacgctagca actactgcag
     1141 aaagacgtcc aagtggtaca tcagttgcgt caactacgta ccatttacgt tcaacttggc
     1201 ctggtttagc cataaatgtt gttttgttca tgatttctcc tatatatagt tcgatttttg
     1261 tttacggtga tgggtgttcc ttcccatcga aaagtatttg gaaggttccg gggcctttca
     1321 aatggggtaa acaataccgc ctactatcat accaaatttt acccctaaaa gtcaatagat
     1381 atgaaaaata tttttcggta acttctcaaa gtaactgaaa gttatataat caagttaatt
     1441 tgggaattta cctattaact tcggtagatt tttgggaatt tttttccttc tttttccctg
     1501 tagttaaaat ccttttcaaa aaatcacctt ttcttgattt ttaatcctat ttgctgtatg
     1561 ataagggaaa agaaagggga cagagatatg gcttttacca atacccacat gcggtctgct
     1621 agttttggca ttgttaccag cttgcccgat gacatcattg actctttttg gtatatcatc
     1681 gatcatttct taaaaaatgt ctttgaattg gaagaagaac tcgagtttca attgcttaat
     1741 aaccaaggaa agattacctt ccacttttca agtcaacacc tccctacagc cattgatttt
     1801 gactttaacc atcctttcga ccctcgttat cccccaagag tactggtttt agacatggac
     1861 ggtagagaaa ctatcctcct cccagaagaa aatgacctat tttaatactc aatgaaaatc
     1921 aaagagcaaa ctaggaagct aaccgcaagc tgtacttgag tacggtaagg cgacgctgac
     1981 gtggtttgaa tttgattttc gaagagtata aaaactctag ccttcagttg caagtgactg
     2041 aaaactagag tttttctatt ttttcaaagc atcatacaag ttgcggatcg gttgttttaa
     2101 tatcggatgg ataaaatgag gcgcaatttc ctgtaaggac tcaaggacaa aaaggcgttc
     2161 cgctatgtaa ggatgaggca atatgaggtc gtctgtataa aggatctggt cctccacaaa
     2221 gagcaagtcc aaatcaatca aacgaggtcc ccaatgcact tctctcaccc gtcccagctc
     2281 tgactcaatg gctaacaagg tttctaacaa gtcttgtgct ggtagccagg tttccacctc
     2341 aaccacttga ttggcaaagc tatcctgctc cactccaccc caaggctccg tcgctaagac
     2401 actggactct ttgagaatat ggatgccacg agctcgcagt ttgtcaatgg cttgcttcaa
     2461 gtttgcttgt ttatctccca tattgcttcc tagggcgata aaggctcgtt gcttgcggcg
     2521 atgaatggtt accgagcaag tatctagtga caaatgcacc ggtgcccaag gttttttcag
     2581 ttccaacttc atttcttgga caagaggata agactcaaag gtacgttcca ccagtttata
     2641 ggctaccgtt tcaatcaaat cttcactcgt ttcctgaaac caagtcgtcc actgctgaca
     2701 caattctccg taatggacag aggctgttaa atccaagtct gtagctgcct tggtcatatc
     2761 ataggatagg atggctgaaa cgacaaattt ctgccccaat tctttctcac taggaaaaag
     2821 accatgatag gcaaacattt ccaaatcctt aatctgcagt tgatccataa tgattccttt
     2881 ctagaaaaat ccgcttgaag cggattcttt ttatagcccc attaaacgat aagcttggtc
     2941 acggagatcc ttatctgttt caaatagacc acgagctact gtcgtcaagg ttgcagtgcc
     3001 tggttttcta acaccacgca tactcataca catatgttcc gcctcaatga caacaaaggc
     3061 tcctttagca cctagatagt ccatcaaggc atcggccact tcgatattca aacgttcttg
     3121 aatttgtggt tttttcgaat aaacttcaac cgtacgggct agcttagaca agcctgccac
     3181 acgaccatct ggaatgtagg caatgtgcgc tctaccataa aatggcaaga agtggtgttc
     3241 acacatggta tggaaaaaga tatccttttc taccaccata ttatcgtcaa taatttcaaa
     3301 ggattttgac aaatgttcct ctgctgtttg accaagacct gaaaaaatct cttgatacat
     3361 acgggctaca cgagcaggtg tttcctgcaa gccctcgcga ttagcgttct ctcctacagc
     3421 ctcgataatc atttttacag ctgcttcaat cttttgtgta tccattctcg ttcttcctct
     3481 ccatcagata ggccctcact tggctcaaga aatacaagga acctgtgaca atcctaactg
     3541 tttgtttctc ttctttttta tctgtcaaat tctgctctag aaaatcatgc caatcttggt
     3601 agctgagatt tctagcctta gctgcctctt tcagcacgct ttcatccgtc gcccgactat
     3661 ccgcaaaatg tgttagagta agctcggtat ctggcatggc tcccagcaag tccaacatat
     3721 cctccaaggc tttggttttg atacaagtga agaggatttc cttatgatga tccgcaaaac
     3781 gttcttgcaa ggttaccaac aaggccttga tagcatgggg attgtgggct ccatccaaaa
     3841 tcatcaaggg atctcttgac acgatttcca aacgccctgg ccaacttgtt tcttccaagg
     3901 cttgaccaag aaagtcattg cttgctagct ctcgaccatc ttcttgacaa aaagtatcaa
     3961 gtaaagctat ggccatccca gcattctcta tttggtacaa accaagcagg ctagtctgga
     4021 agcaaccttg tctgacagca cttgtatagt caaagacttc ccctgtcacc acactttctt
     4081 gatgacgaac ctgataatct gtcccgtagg caagtctcgg cgcatctttc tcttccgcaa
     4141 tgcggtcaat cacagctaag gcttctggag caatacgccc tgttaccaag ggcatccctt
     4201 gtttgataat acctgccttc tgctctgcta tggactccaa ggtgtcacca agtagggcca
     4261 catgatccaa gccaatagtt gtaattcctg tcaaaatggg ctgacagaca ttggtactat
     4321 ccaaaagtcc acccatgcca acttccatga tggccacatc tacttgctct gaggcaaagt
     4381 agtcataggc cagggctgtg ataatctcaa actcggttgt gccctgtaaa ttggcgaccg
     4441 cttctccctc cagcaaagac tgatagtctg ccatgagagc ttctagcctc gcttctgaga
     4501 tcgattcccc attgatgcta atctggtctg tgtaatgaat gagatagggc gagctaaaca
     4561 cgccaactct caaccctagc ttttctagca tctttttcaa aaaagcaata gtcgagccct
     4621 tgccgttagt ccctccgata tggaggacct tgagtttgag atggggattg ccacgcaaag
     4681 ctaacagttc caccattcgt tccaagccaa aatgcggttg atccgtccgg tagttagcaa
     4741 tccactgatt gttttcaatt tctttcatct tatttatatt gttttaaatc taaattttcc
     4801 gcttcatcag ccagacgaat ggcagaggca atttcaactg ccatcctgtg actagctacg
     4861 tcatgcacgc gcaccacttc tacaccctgt ctcgcagcga tactagttac atgagccgaa
     4921 gccgtgtccc gatttcggaa accaagctct gtctcaggat tgacttcaaa accattctcc
     4981 tctaggatat tgatgacaaa tcgcttgcgc gacactccga gaaagattgg atagcccttc
     5041 tgatgtagtt tatccaggtc ccgtaaaaga agcagatttt ctttcttggt cagaccaaag
     5101 ccaattcctg gatccaacag gatattttct ggtgcaatac cagcttctgc cgctctcgct
     5161 agtgctcgtt caaagaaagc ctccatcaat tcttcgattg gcaatgtttc aaagtccgct
     5221 aactcttttt ctgtaaaggt ttgaccaaaa ccaaaatgag ggaagataag cgaactagga
     5281 tgctgaggcc gagccataac tgggttaaac atgatgacca cttgcgctct cgcttcagct
     5341 accacatgag ccattttctc atcacccata agaccagtga tatcattgac tagatcggca
     5401 ccagcagcca aagcagcctc tgctacttga ctcttccaag tatcaataga gatgaggaca
     5461 tcactttcct tgcgaatcgc tttgatcact ggaacaacac gctggatttc ctcttctatc
     5521 tcaacatagc tactgcccgg ccgagtcgat tctccgccga tatcgagcat actggctcct
     5581 tctgctatca atttacgagc ctgctggagt gcctgctcaa gagcaaaaaa ttgaccaccg
     5641 tccgaaaagg agtctggggt tacattgata attccgcaaa tagctgtttt tgcatgattg
     5701 gctttacttg acatatcggt cactccctca aggcttttca tcttattatt tttctatttt
     5761 accataaaaa gaaaaagatg gacacgattg cattcatctt tccctagtag aaagaggtcg
     5821 gtttctacat aaaagctttt aaacagaaat tcctaatgtc cgactcataa tcaccacaag
     5881 agccaacaaa cagaaagcaa tcccattaac aatcatgtga agcaagatcg acatttccaa
     5941 acgttgggtc ttgtaggccg tccaagatag aactgtcgac atacctccat aaatcaataa
     6001 agaaggtaaa ttacttggtt gatgcaataa agcaaacaca atcgtaccga ctacaaatcc
     6061 caagttctcc ttgcctcgga aaatcttttt aggaacaatc ccacgacaca agatttcctc
     6121 acaaatcgga gcaagcaagg ctagcaagaa gaaactggaa atcaacgaac tattttgaac
     6181 catatcatta atctgagact ggttagctgt tgtcgtctca tttgacagtt gcaacaagat
     6241 agaaccaagt atatttgacc cgacaataac taaataactc aaacccaaac gtgccaaatc
     6301 tttagctcta aaaaaagaaa aattaaaact agctaacttg gttttacgag ctcccataat
     6361 aaatagagcc agaaccacaa ttgaaaggcc agcaaccatc agccctgact gtagcagggc
     6421 tacttctttt aaagtcaaaa tagaggtaac cactagggga acctgatata aaaggacggc
     6481 aagtaaaaag accaaaatcc agcctgcacg attcaacaat tctttccaca tatttttctc
     6541 tttcatcacc tatctccttt gtattaaaaa aggggggaaa tccccctggg tcattctatt
     6601 ataaggccat gctaatgtag ttaaggataa acaaggcatc caaaatccaa atcatggcat
     6661 gaacatcttt aacttgacct ttaacaagct tagtcaaagt gtaagtcaag aaaccaactg
     6721 caatcccttg agtgatagag tagctgaatc ccataaagat agatgtgaag aaggcaggaa
     6781 ctgcttcaga catatcatcc caatggatat ttttcaagct accaagcatc ataatcccaa
     6841 cgataatcaa gattggagct gtagccgctg ttggtacgat cgctagaagt gggctaaaga
     6901 agcttgaaat cgcaaaacag atagctacaa ccaaggctgt caaaccagta cgtccacctg
     6961 caccgatacc agcagcagac tcaacataag tcgttacgtt tgaagtacct gcaatggcac
     7021 cgactgtcgt tccaatcaaa tcagagtaaa gagccttatc caatttggct gattggtgat
     7081 tttcaccatt tgtcgctaca ataccaactt tttcacctgt accgatcaag gtaccaattg
     7141 tgtcaaaaat atctgtcaat gagaaggcaa gaatggccat cagagtttca ggcaagcgag
     7201 ctgtatctga aaccaaagct cctaaacctt ctgaaccaag agctgcacca aagattgtct
     7261 tcaaatcttc aaaagctgca ccaacatggt tattagcaaa atcgatacta gacaaatcaa
     7321 ccaaaccaac tgcaatagca agaacagttg ttgtcaagat agagagaata attccccctt
     7381 taatcccttt gatgacaaag aagatagtaa tggcaagtcc tgcaagagcc actaaaacag
     7441 ctggattatt aaagctgacc aatcctggaa ctgctgaaga gtttgctgca atcgttgctt
     7501 gagctttgtc agccccttct cctacaacag tatagttgcc tggatcaatc gtgaatttca
     7561 aaagtccagc attcttaatc cctacatagg caaggaagac accgatacca gctgaaatag
     7621 ctgagcgaag agcattggga atcgattcaa tgatcatttt acgaaccttt gtcaaggtaa
     7681 taatcaatga aataatccca cagatgaaga ccatagctag ggcttcttgc caagaataac
     7741 caagcccgaa tacaactgta aaggtaaaga aggcattgag tcccatacct ggcgcttggg
     7801 cataaggtaa gttagcataa aaagccatca tcaaggtacc cgctactgca ccaataatcg
     7861 tcgctaggaa gacaccctga gcaggcattc ctgtttgtga aagtatttgt gggtttacaa
     7921 agagaatata gctcattgca aagaaagttg ttaaaccagc gagaacctct gtacgaacgt
     7981 ctgtaccgtt ctcttttagt ttaaataatt tgtccatcat caatctcctt ttaattttta
     8041 cgaacaataa tagaattata tcatttatca ttcacttttt caatgtcttt gtttgatttg
     8101 tttaagaaat taatccaatt tcattttttg tttggaatct gcttttctgc ctgctttctg
     8161 ttataataga agacatctta tctgaaaaca cactagaaag gtccatatga cgaaaaaaat
     8221 tattgcagtt gacctggatg gaaccctgct caactcagac agtcaaattt ctgactttac
     8281 caaaaaaacc atcaaaaaag ttgctgaaaa aggccatcag gttattatta cgacaggtcg
     8341 cccttaccgt atgtcaaaag atttttaccg tgaactgggc ttagacactc ctatgattaa
     8401 cttcaacgga tcccttactc atttaccaga ccaagtttgg gattttgaaa agtgtttgac
     8461 tgtagacaaa aaatatctgc tagatatggt tcaacgttca gaggacattc aagccgattt
     8521 tatcgctgga gaatatcgta aaaaattcta cattacaaat cccaatgaag agattgccaa
     8581 tcccaaacta tttggtgtag aagctttcca gcctgaagat caattccagc ctgaattggt
     8641 gaccaaggac cctaactgta tcctcttgca gaccagagcc agtgacaaat atgccttggc
     8701 aaaagacatg aacgccttct accagcatca actttctatc aatacctggg gaggtccgct
     8761 caatatcctt gaatgtaccc caaaaggtgt caacaaggcc tttgctttgg actacttgct
     8821 caagataatg aatcgtgaca aaaaagattt gattgccttt ggagatgaac acaatgatac
     8881 cgaaatgctc gcttttgctg ggaagggtta tgccatgaaa aatgccaatc cagagctact
     8941 tccttatgca gatgagcaaa tttcccttac caacgaccaa gatggggttg ccaaaaccct
     9001 acaagactta ttcttataac ctatactgat actcaatgag aatcaaagag caaactagga
     9061 agctagccgt aggttgctca aagcactgct ttgaggttgt agatgaagct gacgtggttt
     9121 gaagagattt tcgaagagta tgaccagctt gcaagctggt ctttgtgctc ttttcacagt
     9181 ctcatcaacc agttaatcga ttgttctact ttttgtctcc aaaaccttgg aaaaggcttt
     9241 cttttgtgat atacttcaca tataaataca agagagctcg tcacactcga ctctgttgac
     9301 aaaaaatcaa tccagtcccg ttgtccctgt tctcggtcaa tatcaaggag gatagctatg
     9361 aaagctgttg ttgtaaatcc agaaagcact ggtgttgcta ttgaagaaaa agtactccgt
     9421 ccacttgaaa ctggggaagc acttgtagaa gttgaatact gtggcgtttg ccacaccgac
     9481 ctccacgttg ctcatggtga ctttggtcaa gtcccaggac gtgttcttgg gcacgaaggt
     9541 atcggtatcg ttaaagagat tgctccagat gtgaaaagcc ttaaagtcgg tgaccgcgtc
     9601 agcgttgctt ggttctttga aggatgtggc acttgcgaat actgtacaac tggtcgcgaa
     9661 accctttgcc gtacagtgaa aaatgctggc tactcagtag acggtggtat ggctgaacaa
     9721 tgtatcgtaa ctgctgacta tgctgtcaaa gttcctgacg gacttgatcc agcccaagct
     9781 tcttctatca catgtgctgg agtaacaacc tataaagcta tcaaagaagc aaaagttgaa
     9841 ccaggccaat gggttgttct ttacggtgct ggtggacttg gtaacctcgc tgttcaatac
     9901 gctaaaaaag tattcaatgc tcatgttatc gcagtcgata tcaacaatga caaacttgcc
     9961 cttgcaaaag aagtaggcgc tgacattgtg attaacggcc tcgaagttga agatgtagct
    10021 ggactcatta aagaaaaaac tgatggagga gctcattcag ctgtcgtaac tgctgtgtct
    10081 aaagttgcct tcaaccaggc tgttgactcc attcgtgctg gtggtcgcgt cgtcgctgtt
    10141 ggtcttcctt ctgaaacgat ggaactcagc atcgttaaaa cagtcctcga tggaatccaa
    10201 gtcatcggtt ctcttgtcgg aactcgtaaa gacttagaag aagccttcca atttggtgca
    10261 gaaggtctgg tagtcccagt tgttcaaaaa cgtccagtag aagatgctgt tgccattttc
    10321 gacgaaatgg aaaaaggcca aatccaagga cgtatggtac tcgacttcac ccactaatct
    10381 aatagaaacc tattttaaaa gttggaagct tcttccaact tttttata
//
LOCUS       DAVKUR010000060        10341 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKUR010000060 DAVKUR010000000
VERSION     DAVKUR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.060"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            145..3246
                     /locus_tag="VW749_001805"
     CDS             145..3246
                     /locus_tag="VW749_001805"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0175798.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQKSEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3328..4335
                     /gene="pfkA"
                     /locus_tag="VW749_001806"
     CDS             3328..4335
                     /gene="pfkA"
                     /locus_tag="VW749_001806"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0175799.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     L"
     gene            4394..5899
                     /gene="pyk"
                     /locus_tag="VW749_001807"
     CDS             4394..5899
                     /gene="pyk"
                     /locus_tag="VW749_001807"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0175800.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6633..6858)
                     /locus_tag="VW749_001808"
                     /pseudo
     CDS             complement(6633..6858)
                     /locus_tag="VW749_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7706..8578
                     /locus_tag="VW749_001809"
     CDS             7706..8578
                     /locus_tag="VW749_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0175801.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            8591..8755
                     /locus_tag="VW749_001810"
     CDS             8591..8755
                     /locus_tag="VW749_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175802.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(8724..9068)
                     /locus_tag="VW749_001811"
                     /pseudo
     CDS             complement(8724..9068)
                     /locus_tag="VW749_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9211..9522
                     /locus_tag="VW749_001812"
     CDS             9211..9522
                     /locus_tag="VW749_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175803.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9526..10242
                     /locus_tag="VW749_001813"
     CDS             9526..10242
                     /locus_tag="VW749_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0175804.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         3211 a         1783 c         2192 g         3155 t
ORIGIN      
        1 caatatagta taaatataaa aatgatgaca aaaatacaaa tgaatagaaa ataaattagt
       61 aagctgatga aatttttctc aagagaagcc atttataggt gaaaatggta taatatagtg
      121 agaaggatag aggagaagtg taaattgatc gcacaactag atacaaaaac agtctatagt
      181 tttatggaaa gcgtcatttc gatcgaaaag tatgtgagag cagctaaaga atacggctac
      241 actcatttgg ctatgatgga tattgacaat ctttatggcg ctttcgactt tctagagatt
      301 acaaaaaaat acggcattca tcctttgcta gggcttgaaa tgacagtgtt tgtagatgat
      361 caggaagtga atttgcgctt tttagctcta tctagtgtgg gctatcagca gttgatgaag
      421 ctttcgacag ccaagatgca gggggagaaa acttggtcag tcctgtccca gtacctggag
      481 gatatcgcgg tcattgtgcc ttattttgat agagttgagt cgttagaact aggctgtgat
      541 tactatatag gggtttatcc agaaacacta gcaagcgaat ttcatcatcc tatcttacct
      601 ctttatcggg tcaacgcttt tgaaagcagg gatagagaag ttcttcaagt tttaacagcg
      661 attaaagaaa atctaccgct cagagaagtt cccttgcgtt cgagacaaga tgtctttata
      721 tcagcaagtt ctttagagaa actattccaa gagtgttttc cgcaagcttt ggacaattta
      781 gaaaagctta tttcaggcat ttcttacgac ttggatacta gtctgaaact gcctcgtttt
      841 aatccagcta gaccagcagt agaggagttg agagagcgtg ctgaactggg gcttgttcag
      901 aaggggttga ctagtaaaga atatcaagat agactagacc aagaattgtc tgttattcat
      961 gatatgggct ttgatgatta tttcttggtt gtttgggatt tgttgcgttt tggacgatcg
     1021 aatggctatt atatgggaat gggaaggggt tctgcagtag gcagtttggt ttcttatgcc
     1081 ttagacatca cggggattga cccagtagag aaaaatctga tttttgaacg ctttcttaat
     1141 cgtgaacgct ataccatgcc tgatattgat attgatatcc cagatattta tcgtccagat
     1201 tttatcagat atgttggtaa taaatatggt agtaaacatg cggcacaaat cgttactttt
     1261 tcaacctttg gagccaagca agctcttcga gatgtcttga aacgctttgg tgtgccagag
     1321 tatgaattat ctgcaattac taagaaaatc agttttcgtg acaatcttaa gtcggcctat
     1381 gagggcaatc tccagtttcg tcagcaaatc aatagtaagt tagaatacca aaaagctttt
     1441 gagattgctt gcaagataga gggctatcca agacaaacct ctgtccatgc ggctggtgtt
     1501 gtaattagtg accaagattt aaccaactat attcctctaa agtatggtga tgaaattcca
     1561 ctgactcagt atgatgctca tggagttgag gctagcggac ttttgaagat ggactttctg
     1621 ggactacgaa atttgacctt tgtccagaag atgcaagagt tgcttgctga aatagaaggt
     1681 attcacctta aaattgaaga aatagatttg gaagacaaag aaacgttagc tttatttgcc
     1741 tctggaaata caaaaggtat ctttcaattt gagcaaccag gtgccattcg tctgcttaag
     1801 cgtgtgcaac cagtctgttt tgaagatgtc gtcgcgacta cttctctaaa tcgaccgggt
     1861 gctagtgact atatcaataa ttttgtggca agaaagcatg ggcaggaaga agtgactgtt
     1921 ctggatccag tactggagga tattttggct ccaacctacg gcataatgct ctatcaggag
     1981 caggttatgc aggttgccca gcgatttgcc ggatttagtc ttgggaaagc cgatattttg
     2041 cgtcgggcta tggggaaaaa ggatgcctct gccatgcatg agatgagggc ttcctttatt
     2101 caaggttcat tagaagctgg tcatactgtg gaaaaagcag agcaggtctt tgatgttatg
     2161 gagaagtttg caggttatgg ttttaacagg tcacacgcct atgcctactc agccttggcc
     2221 ttccagttgg cttattttaa aacacattat ccagccattt tttatcaggt catgttaaat
     2281 tcttccaaca gtgattactt aatagatgca cttgaagcag gttttgaagt agcctctcta
     2341 tccatcaaca ccattcccta tcacgataaa attgccaaca aggccatcta tctaggtttg
     2401 aaatccatta aaggagtcag taatgattta gctctctgga ttattgaaaa tagaccttat
     2461 tctaacattg aagattttat agctaaatta cctgagaatt atctgaaact tcctctgcta
     2521 gaacctttgg taaaagttgg tcttttcgat tcatttgaaa aaaatcgtca aaaagtattt
     2581 aataatttag ctaatctatt tgaatttgtg aaagagttgg gaagtttgtt tggagatgct
     2641 atttatagtt ggcagaaatc ggaagattgg acggaacaag aaaaatttta tatggaacaa
     2701 gagcttttag ggataggtgt cagcaaacat ccactacaag ctattgcaag taaggctatt
     2761 tacccgatta ccccaatcgg aaatttgtca gaaaatagct atgctattat tttggttgaa
     2821 gttcagaaaa taaaagtgat tcgtaccaaa aagggtgaaa atatggcttt cttacaggtg
     2881 gatgacagta agaaaaaatt ggatgttaca ctcttctcag atttatatcg acaggttggt
     2941 caggaagtaa gagaaggagc attctactat atcaaaggga aagtccaatc acgtgacggt
     3001 cgtctgcaaa tgattgcaca agaaataaga gaagcagttg ctgaacgctt ttggattcag
     3061 gttaaaaatc atgactcgga tcaagagatg tcacgtattt tagaccagta taaaggccca
     3121 atcccagtca tcatccggta tgaagaggaa cagaaaacca tcgtttctcc ccatcatttt
     3181 gtagctaaat ctgatgaatt agaggcgaaa ttgaatggaa tagttatgaa aacgatttat
     3241 cgctaaaatt acggaaaata gaagaatttt caacgtaaat gtggtataat cagtaagaat
     3301 gttaaaagaa aaaggagcat aaccaatatg aaacgtattg ctgttttgac tagtggtgga
     3361 gacgcccctg gtatgaacgc tgccatccgt gcagttgttc gtcaagcaat ttcagaagga
     3421 atggaagtgt ttggtatcta tgacggatat gctggtatgg ttgccggtga aattcatccc
     3481 ctagatgcag cttcagtagg ggacatcatt tctcgtggtg gtactttcct tcactcagct
     3541 cgttacccag agttcgctca acttgaaggg caacttaaag ggattgagca attgaaaaaa
     3601 cacggaattg aaggtgtagt tgttatcggt ggtgacggat cttaccacgg cgctatgcgt
     3661 ttgactgaac atggcttccc agctattggt cttccaggta caatcgataa cgatatcgtt
     3721 ggtactgact ttacaatcgg ttttgacaca gcggttacta ctgccatgga cgctatcgat
     3781 aagattcgtg atacatcatc aagtcaccgt cgtacttttg taatcgaagt tatgggacgt
     3841 aacgctggtg atatcgctct ttgggctggt attgcaactg gtgctgatga aatcatcatc
     3901 cctgaagcag gcttcaagat ggaagatatc gtagcaagca tcaaagctgg ttatgaatgt
     3961 ggtaaaaaac acaatatcat cgtcttagct gaaggtgtga tgtcagcggc tgaatttggt
     4021 caaaaactta aagaagctgg agatacaagc gaccttcgtg taacagaact tggacatatt
     4081 caacgtggtg gttctccaac tgcgcgtgac cgtgttttgg cgtcacgtat gggtgcacat
     4141 gctgttaaac ttcttaaaga aggtatcggt ggtgttgcgg ttggtattcg taacgaaaaa
     4201 atggttgaaa atccaattct tggtactgca gaagaagggg cattgtttag ccttactgca
     4261 gaaggtaaga ttgtggttaa caacccacac aaagccgata ttgagctatc tagcttgaat
     4321 aagagcttgt tataatttac aatttagtta ataagaccaa aaaggtcata tatataaagg
     4381 agtcacaaaa atcatgaaca aacgtgtaaa aatcgttgca actttgggtc ctgcggtaga
     4441 aatccgtggt ggtaaaaaat tcggtgagga cggatactgg ggtgaaaaac ttgatgttga
     4501 agcttcagct aaaaacattg ctaaattgat tgaagctggt gctaacacat tccgattcaa
     4561 cttctcacac ggcgaccacc aagaacaagg tgagcgtatg gcaactgtta aacttgcgga
     4621 aaaaattgca ggtaaaaaag ttggtttcct tcttgataca aaaggacctg aaatccgtac
     4681 agaattgttc gaaggtgaag ctaaagaata ttcatacaaa actggtgaaa aaattcgtgt
     4741 tgcaactaaa caaggaatca aatcaactcg tgaagtgatt gcgttgaacg ttgctggtgc
     4801 tcttgatatc tatgatgatg ttgaagttgg tcgtcaagtt ttggttgacg atggtaaact
     4861 tggtcttcgt gtggttgcta aagatgatgc aactcgtgaa tttgaagttg aagttgaaaa
     4921 cgatggtatc atcgctaaac aaaaaggtgt gaacatccct aacactaaaa ttcctttccc
     4981 agctcttgct gaacgcgata acgacgatat ccgtttcggt cttgaacaag gtatcaactt
     5041 catcgcaatt tcattcgtac gtactgcaaa agatgtgaac gaagttcgtg caatctgtga
     5101 agaaactgga aacggacatg ttcaattgtt cgctaaaatc gaaaaccaac aaggtatcga
     5161 taacttagac gaaatcatcg aagcagctga tggtattatg attgctcgtg gtgatatggg
     5221 tatcgaagta ccgttcgaaa tggttccagt ttatcaaaaa atgattatca agaaagtcaa
     5281 tgctgcaggt aaagttgtta tcactgcaac aaacatgctt gaaacaatga ctgaaaaacc
     5341 acgtgcaact cgttcagaag tatcagacgt attcaacgct gttatcgacg gaactgacgc
     5401 tacaatgctg tcaggcgagt ctgcaaacgg taaataccca ctcgagtcag taactacaat
     5461 ggctacaatc gacaagaacg ctcaagctct tcttaatgaa tacggacgtc ttgattcaga
     5521 ttcatttgag cgtaactcta agacagaagt aatggcttct gctgttaaag atgctactag
     5581 ctcaatggat atcaaattgg ttgtaactct tactaagaca ggtcatactg cacgtttgat
     5641 ttctaaatac cgtccaaatg ctgacatctt agcattgaca tttgacgaat tgacagaacg
     5701 tggcttgatg ttgaactggg gtgttatccc aatgttgaca gatgctccat cttcaactga
     5761 cgatatgttc gaaatcgctg aacgtaaagc ggtagaagca ggtctcgttg agtcaggcga
     5821 tgatatcgtt atcgttgctg gtgtgccagt aggagaagct gttcgcacaa acacaatgcg
     5881 tatccgcaca gtacgttaag aaaaatataa aaacctatca tatccagctt tctagcctgt
     5941 atgatgggct ctttttttgt ccagggggca aaaagggggc aaaactttca taatggattg
     6001 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtata tatgttactg
     6061 acttcgtcag ttctatctac aacctcaaag cagtgctttg agcaacctgc ggctagcttc
     6121 ctagtttgct ctttgatttt cattgagtat gaaataagat atgcacaaat tgattaggaa
     6181 attcaaatga atttctacaa atgttttagc aatcgcaatc tacttgtcta gattcgatct
     6241 gatatatttt cgatttaatg atatggtatt taaaacctcc aaagtagctt gctccattct
     6301 tttacttacg tgagtgtaga tgttatttac tgttttagcg tttttgtgtt ctactctaac
     6361 cattatagca ttcttctcag ctagtgtact aaggagtgtg tgcctgaaaa tatgggaact
     6421 aagggctggt ttatcggttt ctctagttta gtatttgcct tttgcaaagt gatcttaaat
     6481 gcctttctct aaatttacat atcactattg tttaacaaaa tctaatctac tttaggtcac
     6541 ttattctttt tttgaaatgt agaatgaact ttttcaaagt ttttcgaatc ttttaaaatc
     6601 tgtttgtttt atatcgccat tctccccctt ttttaattct ccctatatag cctgacaact
     6661 ttcccgatgg tacgaatatg gttgctttcg tctaggtgga tgtcggagta ttcgggattg
     6721 agtttttttg aggtagcctt ggcggagttt cttgacatag ttagtgccgt ctacttggaa
     6781 gatgccgatg gtattatagt caatctgtgg ggtattcttg ataaataggt agtcgctgtt
     6841 tcttatcttt ggctccatgg acttgctgac gacataagcg attgggtcgt agtcgtctgg
     6901 gataatggaa actccataac taaatcgtcg tcctgcatca agcggctacc tgcagagata
     6961 aactacctaa cacgagagta agtagtctgt ctgtagtcgt ccagtctgat gatttttacg
     7021 atacttcgtt tttctgatca tacagttgcc tctcggcata ggtcagaact ttaccttgtc
     7081 tgggtggtgc ccgttggtcg tagatagatt ggatatcgct aggagaatcc ttttgaactg
     7141 gaggaaagag ggcatcaatc aagctactga atactttaac taagtcaaat atagtatttt
     7201 tcttagtaga cctaaccctt ttttcataat ttctaatggt gtttttactt atacctatct
     7261 tagtacccaa ttcttattga gtccaaccat tactagtcta tattgtttta tagttgattg
     7321 agtttggaat agtacgctgt agctgctaaa acatttctag gaattaattt gcctttccta
     7381 atagagttgt tcatatctta tttcaatcta ctatattttt cacctctaac aatcgcaatc
     7441 tcttctttat ccatgaacga aaacgctttc tatctttgta agtaaagcat cacacgaaat
     7501 ccacgaaaat gaaaaccttt gttgtgtttt cgtaaaaaat ttgttgacag agcacgaaac
     7561 gcctactata attaaatcaa gtttaaggaa ataacaaaaa aacaaatcgg agggaaagac
     7621 gatgaacaca ttaaatgaga aagtaatcaa tatctgtaaa gcagtagtta aagaaacttt
     7681 aatccaagac atttaggaga aagaaatgaa gaaatcaaga aaattagcca cattaggaat
     7741 ctgttcagcc ttgtttttag gcttggctgc ttgtcaacaa caacatgcta cttctgaggg
     7801 gacgaatcaa aggcaaagca gttcagcgaa agttccatgg aaagcttcat acaccaacct
     7861 aaacaaccag gtaagtacag aagaggtcaa atctctctta tcagctcact tggatccaaa
     7921 tagtgttgat gcatttttta atctcgttaa tgactataat accattgtcg gctcaactgg
     7981 cttatcagga gatttcactt cctttactca caccgaatac gatgttgaga aaatcagtca
     8041 tctctggaat caaaagaagg gcgatttcgt tgggaccaac tgccgtatca atagttattg
     8101 tcttttgaaa aattcagtca ccattccaaa gcttgaaaag aatgaccagt tgcttttcct
     8161 agataatgat gcgattgata aaggaaaggt ctttgattca caagataagg aagagtttga
     8221 tattctattt tcgagagttc caactgaggc aactacagat gtcaaggttc acgctgaaaa
     8281 gatggaaaca ttcttctcac aatttcaatt caatgaaaaa gctcgaatgc tgtctgtagt
     8341 cttgcacgac aatctggatg gcgagtatct gtttgtaggt cacgttgggg tcttagtacc
     8401 tgctgatgac ggtttcttat ttgtagagaa attgactttc gaagaaccct accaagcgat
     8461 taaatttgct agtaaggaag attgctacaa gtatttgggc accaagtatg cggattatac
     8521 aggcgaggga ctggctaagc cttttatcat ggataatgat aagtgggtta aactttaata
     8581 gtgttatgat atgacagtaa tcttaggatt tttatttcta tttttgatga cttggtgggt
     8641 tatttcaatc gttaatagcc agaaaccact caaaaatgaa acatttattg gctatgtcca
     8701 aagatacgat attgatggga atggctatca atcattaccg tgtcctcaga actgagagga
     8761 gttcttgaaa tcgtaacacc actttgaaca agagttactt caacccattg gctccgccgg
     8821 agtaagttgc tttcgtgaac accaaaatca gccgcaattt cttcataagt gcggtattct
     8881 cacacatatt gaagagtggc cataagaagg tcttctaggc ttaatttagg ttttcgtcca
     8941 ccttttgcgt gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtg
     9001 gtacgctgaa caccaacaag acgcttaaat cgtgcatcag ttagttgttt acttgcttca
     9061 tcattcatag aactactata ccatattttg tttcgcagga agtctaatgc taaaatctta
     9121 tcagtgagaa gatttcttaa agtttattct ttgtagtttc atctgtatta gtacataatt
     9181 taacttagag aaaataggag gactaatcga atggaattaa aagattttac agaaaaagaa
     9241 caggaaatga ttaagaaaag gcttacaatg tctaatatta gtgacaaaga aactactgag
     9301 aagattctgg cgctagtacc acaagacttg attaagcgaa tcccgttttt tgtcagaaaa
     9361 catgctacaa cacgtacgat taaacgcatt tcaattgaat accctgaact ctacgctgta
     9421 gctcaaacaa gtggtgagat tccagaaaaa gaacgcgaag aattgcgtca gattatcaca
     9481 actatctttg aacaaaagat gaataagcat agtattaagt agagaatgaa aaaatatttt
     9541 attagcggtt tgggaagcaa tgcctatcat agcaaggatt tttttcaaga actagattcg
     9601 caggtctatt ttctaaatcc atatgaaaag catcttcgag atgaaacaga attgaaatca
     9661 tggtttaaaa atgagattgt agaggaagaa tctatctgtc tgataggcca ttctcttgga
     9721 ggagatttag ctcgttattt cgcatcggaa tttgaagaag taaagaaact gattcttttg
     9781 gatggtggct atctagattt agataagatt ttacctttgg atacagagtt agaggaaact
     9841 aaaaattata tcaaatctca aattgtttcg gacttagctc ttcttatttc taaagagaag
     9901 tccgaagcaa agcattggtc agaaaatatg gagaaagctg taagacagtc ctatcactgg
     9961 aatgttgagt ataatagata tgagttggct ataaattatg aaaatataga agcgatactc
    10021 cgcctacgga gaaaaataca agcttttaag agagaagtgg gagatacctt gtttattagt
    10081 cctcgctatc ctaatggagc tacatggaga gaggaagccc taaaagaatt gccagactat
    10141 tttaatacta tttttttaga aaactttggc catgagcttt atactcaagc acctaaagaa
    10201 atcgctagtc taatgaatga gtggctcgct tattttctat gagctacttg tattgctgga
    10261 aatggtataa gatgaaaatc tacaggctct ataatatttg tagtgggtaa atccactata
    10321 gatattatgg agcctatttt t
//
LOCUS       DAVKUR010000061        10041 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKUR010000061 DAVKUR010000000
VERSION     DAVKUR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.061"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(71..307)
                     /locus_tag="VW749_001814"
     CDS             complement(71..307)
                     /locus_tag="VW749_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0175805.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(375..1295)
                     /locus_tag="VW749_001815"
     CDS             complement(375..1295)
                     /locus_tag="VW749_001815"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0175806.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1493..1897
                     /locus_tag="VW749_001816"
     CDS             1493..1897
                     /locus_tag="VW749_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175807.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            2113..2694
                     /locus_tag="VW749_001817"
     CDS             2113..2694
                     /locus_tag="VW749_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0175808.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQKKQ
                     GAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            2691..3968
                     /locus_tag="VW749_001818"
     CDS             2691..3968
                     /locus_tag="VW749_001818"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0175809.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3986..4648
                     /gene="deoC"
                     /locus_tag="VW749_001819"
     CDS             3986..4648
                     /gene="deoC"
                     /locus_tag="VW749_001819"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0175810.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4635..5024
                     /locus_tag="VW749_001820"
     CDS             4635..5024
                     /locus_tag="VW749_001820"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0175811.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5114..6166
                     /locus_tag="VW749_001821"
     CDS             5114..6166
                     /locus_tag="VW749_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0175812.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6310..7845
                     /locus_tag="VW749_001822"
     CDS             6310..7845
                     /locus_tag="VW749_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175813.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7838..8896
                     /locus_tag="VW749_001823"
     CDS             7838..8896
                     /locus_tag="VW749_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175814.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8899..9855
                     /locus_tag="VW749_001824"
     CDS             8899..9855
                     /locus_tag="VW749_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175815.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9940..>10041
                     /locus_tag="VW749_001825"
     CDS             9940..>10041
                     /locus_tag="VW749_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0175816.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSN"
BASE COUNT         2867 a         1768 c         2310 g         3096 t
ORIGIN      
        1 gataattgcg attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat
       61 ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg cttgctttgt
      121 ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa
      181 gttcttcaga tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag
      241 ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt
      301 ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt
      361 ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt cttgctttta
      421 tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag atttgtgaga
      481 ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg catctgagta
      541 aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt caagaaacgg
      601 tccagatacc aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag
      661 aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat tccctcaaca
      721 attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc gtaaacttca
      781 tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga
      841 agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc
      901 aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta
      961 aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca
     1021 ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct
     1081 tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg
     1141 agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc
     1201 aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg
     1261 ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct
     1321 atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta
     1381 tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg atttataagt
     1441 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
     1501 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
     1561 aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
     1621 gatggaacat gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact
     1681 aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat
     1741 tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag
     1801 tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttgggaat
     1861 tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata
     1921 gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta
     1981 tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt
     2041 ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt
     2101 gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg
     2161 agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag
     2221 aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa
     2281 actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc taaggcttat
     2341 ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc tcggagaaat
     2401 gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa
     2461 ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat
     2521 gaaatcattg agaaaagtaa agatttcttg gaaactagtg gggatttgac aatcgtcatc
     2581 cagaaaaaac aaggggctcc aagtgctaag tccaagatgg agggtgtgtt tggtaattgt
     2641 gaaatcctta aaaaagacaa gggatactat atccttagaa gtgtgaaaga atgagagcag
     2701 ttgatttaat acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa attgaatggc
     2761 tggtagaagg ctatgtgtca ggaactgttc ctgattatca gatgtctgcc tttgctatgg
     2821 ctgtttattt taaaggaatg acgactcgag aaatctctga tttaacgatg aatatggtta
     2881 agactgggca agagtttgac ctgtcagcca ttgatggtgt gaaagttgac aagcattcta
     2941 ctggtggtgt cggcgataag gtaaccttga ttttagttcc tcttgttgct agcttcggtg
     3001 tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca attgataaat
     3061 tggagtccat taagggctat caagtagaac gtagtcaaga ggattttatt cgtcaggttc
     3121 aggatattgg agtatctgtc attgggcaat cagaccagct ggtcaaagca gataagcttc
     3181 tctatgccct tcgtgatgtg accgcaactg tcgacacgat tcctttgatt gcgagttcgg
     3241 tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt gctagacgtg actgtcggtg
     3301 agggtgcctt catgaagacg gttgatgagg cgcgtgagtt ggctcaaact atggtagatc
     3361 ttggtaaggt tgttggacgg aagacagtag cagtgattac ggatatgagc cagcctttgg
     3421 gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt ggagattttg caaggtcaag
     3481 gacgtcagga tattacccac tttatttgtg aattggctca aattatgctt ggtttggcaa
     3541 atgttaacaa aactgttgaa gaagttcgcc aacatcttga gaatggtcaa gcactggcta
     3601 agtttgagga aatggtgcaa gcccaaggtg gagacttgga agacctctat cgtcctgtaa
     3661 atgtagctca tgtggtggaa atccctgctc aggaaacggg tgtcatttca gctcttccag
     3721 ctatggactt tggtctttat gccatgaggc tgggtgctgg tcgtgcagtt aagtctgatg
     3781 ccttggacta tgaaacagga attgtttttg aaaagaagat tggagactcc gttcaaaagg
     3841 gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc acctcaacta gttacagatt
     3901 tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca
     3961 tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa tatatagatc atacgctttt
     4021 aaaacaagat gcaaagaaaa aacaaattga tagtttgttg tctgaggcta gagagtatga
     4081 ctttgccagt gtttgcgtta atccgacctg ggttgaacat gctaaaaaag gacttgaagg
     4141 cacagatgtt aaggtttgca cagtagtagg tttccctttg ggagcaacaa cttcagccgt
     4201 gaaagcattt gagacaaaag aagctatcca aaatggtgca gatgagattg atatggtgat
     4261 caatgttgga gctctcaaat caggtaattt agccttggtt gagtcagata ttcgcgcagt
     4321 agtggaagca agtggtgata agttagtgaa agtcattatt gaagcttgcc ttctgacaga
     4381 ccaagaaaaa attgttgttt gccaattggc ccaaaaagct ggggctgact ttgttaaaac
     4441 atctactggt ttttcaactg gtggtgctac gatagcagat gttacattaa tgcgtgaaac
     4501 agttggatct gatatgggag tcaaggctgc tggtggagct cgttcttatg cagatgctct
     4561 tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca gctggggtag ctattttaaa
     4621 aggagaattg gcagatggcg actactgagt tgattgaact ggcaattgaa accagcaaac
     4681 atgcatatgt cccctattct cactttccta tcggagcagt tttagtagcc aaagacggaa
     4741 gtgtttacac gggagtgaat atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga
     4801 gaacagctat ttttaaggct atatctgaag gccaaagaga attttcagaa ttgattgtct
     4861 atggtcaaac tgaaaaaccg atctcgccat gtggtgcttg tcgccaagtg atggctgaat
     4921 tttttgaaca agatctaaaa gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga
     4981 cggtcgggga attacttcca tactctttta cagacttaaa ctagtctgag tcgctctctg
     5041 agtggcacgg tccttgtggc caaccaatcc atacttgcaa catcgttgca catcttattt
     5101 aggaggttca gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc
     5161 agttggactt gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt
     5221 gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca
     5281 atcagcttgg gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg
     5341 tttcacttac ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc
     5401 tggaagttac aacctaatct tcggtgttgg ttttgccctt cataatgcag ttaaagatgc
     5461 agcaaaagaa cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa
     5521 gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc
     5581 agcaaaaaca actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat
     5641 ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt
     5701 ccaagttgac tacgctggtt catttggtga tgcggctaaa ggtaaaacaa ttgcagccgc
     5761 acaatacgca gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt
     5821 ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat
     5881 cggtgttgat cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc
     5941 aaactttgtt cttgtatcta ctttgaaaca agttggtaca actgtaaaag atatttctaa
     6001 caaggcagaa aaaggagaat tccctggcgg tcaagtgatc gtttactcat tgaaggataa
     6061 aggggttgac ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc
     6121 aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat
     6181 ttcttaggaa gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca
     6241 gtaaagcttg ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag
     6301 gaagagcaca tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt
     6361 ggatttgttg ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt
     6421 ttaggagaaa atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa
     6481 ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa
     6541 gcagctagct tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca
     6601 gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct
     6661 ggagctagca aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct
     6721 gccaaggtag cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt
     6781 tatcgggggg ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa
     6841 attgatgagt tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg
     6901 attacccaca aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt
     6961 gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg
     7021 atggtaggac gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg
     7081 gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat
     7141 ctgtccttgg atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt
     7201 cagtctgaac tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag
     7261 ctaaaagggg attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg
     7321 cacgttccag aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat
     7381 attgcccttc aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca
     7441 aatattactt cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa
     7501 ttagttcctg cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa
     7561 attgatcgag atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt
     7621 gccattgagt atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt
     7681 gttgtcagct ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac
     7741 gatggtaaga ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc
     7801 ttgatggctg gtggaaactt gggaaaggag aagagtgatg tttaaaaaat tacaacaaat
     7861 ttcggttccc ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat
     7921 cttcggttat gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct
     7981 gcgtgggatt ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt
     8041 tgcggttgcc agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg
     8101 ttggattctc agtggttggt ttgccctgtc gcatccagat atgccccgtc ccttgatgat
     8161 tctagcaacc atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat
     8221 tcttagggcc tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt
     8281 cttgtatgta gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga
     8341 ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac
     8401 tggtaactca cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg
     8461 gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca
     8521 tgcttcagaa tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc
     8581 aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta
     8641 tgttcaaggt tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc
     8701 caactcacca attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc
     8761 tcctggtatg aatgctgcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat
     8821 tatcttcttt gtcagtgttc attaccttat cgaacgcttt gttaaaccga aaaaacaagt
     8881 taaaggaggt aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg
     8941 ctgatttact cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt
     9001 ggtgtggtaa acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc
     9061 tttaaccttg aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta
     9121 gcaggattgg ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt
     9181 gcagaccatg ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc
     9241 ttagttaaag ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc
     9301 tttgatttcc cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact
     9361 agtctacttg gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag
     9421 actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg
     9481 ggaatcaacg tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga
     9541 attggcggag cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt
     9601 ggacctggat ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct
     9661 atgctttcta gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg
     9721 ccgttcctac aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt
     9781 cttgtcttag cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac
     9841 atcaaatcaa aataagcata caaaaaaacg tcagttcaat gactgaactg ccccccaaaa
     9901 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaaactaac ttatgatgat
     9961 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
    10021 tttgggataa acaattctaa t
//
LOCUS       DAVKUR010000062         9960 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKUR010000062 DAVKUR010000000
VERSION     DAVKUR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.062"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(115..831)
                     /locus_tag="VW749_001826"
     CDS             complement(115..831)
                     /locus_tag="VW749_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0175817.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1179..2966
                     /locus_tag="VW749_001827"
     CDS             1179..2966
                     /locus_tag="VW749_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0175818.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2963..3439
                     /locus_tag="VW749_001828"
     CDS             2963..3439
                     /locus_tag="VW749_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0175819.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3467..4372
                     /locus_tag="VW749_001829"
     CDS             3467..4372
                     /locus_tag="VW749_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0175820.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4359..5174
                     /locus_tag="VW749_001830"
     CDS             4359..5174
                     /locus_tag="VW749_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0175821.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5181..5585
                     /locus_tag="VW749_001831"
     CDS             5181..5585
                     /locus_tag="VW749_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0175822.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5838..7004
                     /locus_tag="VW749_001832"
     CDS             5838..7004
                     /locus_tag="VW749_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0175823.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7120..8157
                     /locus_tag="VW749_001833"
     CDS             7120..8157
                     /locus_tag="VW749_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0175824.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8365..9219
                     /locus_tag="VW749_001834"
     CDS             8365..9219
                     /locus_tag="VW749_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0175825.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            9369..9626
                     /locus_tag="VW749_001835"
     CDS             9369..9626
                     /locus_tag="VW749_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0175826.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(9734..>9960)
                     /locus_tag="VW749_001836"
     CDS             complement(9734..>9960)
                     /locus_tag="VW749_001836"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175827.1"
                     /translation="TDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYKSPHN
                     KTHTIKVFMYCPPKVRQKESNFWGAVHFNT"
BASE COUNT         2857 a         1844 c         2224 g         3035 t
ORIGIN      
        1 ttctataaaa tattccacaa attatagaat cttccaaaaa taggtaagcg ctaccttttt
       61 ggtgtggtat aataagcata gaaaaagccc aagcgattag ctcaggcttt cttcttagtg
      121 atcacggtca catgagataa atttaatctt gtagtaatca gatcgtttgt aagtttcact
      181 gtattctaaa acttggccag ttgattcgag tttggtgatt ttagtttgta ggacagtagg
      241 gaattgttca tcgactccga ggactgaagc cgcatgttct ggagttggaa agactatttc
      301 gttgatttct tcaaagtgtt catcattcat gtgaatgtgg tagtctaact tgaaacgatt
      361 atagatagaa ctatagtatt caaggtttgg ataatttgcg ttgatatatt gttctgggat
      421 gtaggatgta tggtagatat aaacgacacc gtttgattcg cggatacgtt caatcttgta
      481 gtagaattga tcgccgcgta gacccaattt ttccaagtaa acaagcttgt ttccgcgttc
      541 aattgaaaga acagttacct tatcatcttt agcattgaag agttcaatat ctgaaaactc
      601 tacaagcttg tgtttgcgcg cacgtgaaac gaaggttcct tttccttgtt ggcggacaat
      661 atagccatct ttggcaaggt cgtttaaggc gcgaacaact gtgatagagc tgacatcgta
      721 cattgaaatg agttctgctt cagtgtaaaa tttatctcca ctgctaaact gcccagagat
      781 gattttattt tttaattcgt cttttatgta ttgatatttg ggaattgcca tatttttacc
      841 tctattttcc ttctccatag aaaattttac cataaaagcg aaaaaaatag tagtcttttg
      901 aataaaaaat tagaataata gtttgaaaaa ttaagcgata tagggattgc tcatatttta
      961 taaatgtatt ctatacaaaa ttattttagg tcctatattc cgaatttaaa gagcgtttga
     1021 aatgggtcta aaaatgtttg aaactaattg aatgtgtgta taatagtaaa aatgcagtaa
     1081 atatcccgac aatttctatt gacaattcaa acagattggt ttataattaa tataacaaca
     1141 aatgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt gagatacgag
     1201 atgatttcta tctcgatgga aaatcattta agattttatc tggtgccatt cattatttta
     1261 gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt ggttttaata
     1321 cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag tttcattttg
     1381 acggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt ctctacgcaa
     1441 ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta ccagcttggc
     1501 tcttgaccaa gaacatgcga attcgctcat ccgacccagc atatatcgag gcagttggtc
     1561 gctactatga tcagttattg ccaagactgg ttcctcgttt gttggacaat ggtggcaata
     1621 ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag gcttacctga
     1681 gagcgattcg acagctaatg gaagagtgtg gcgtaacctg tcccctcttt acatcagatg
     1741 gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc tttgtaacag
     1801 gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc tttgatgaac
     1861 atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttt aatcgttgga
     1921 aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga gaagttttgg
     1981 aacaaggctc catcaatctt tacatgttcc acggtggtac aaactttggt ttcatgaatg
     2041 gttgctcggc tcgaggaact ttggacctgc cacaagttac gtcttatgat tacgatgccc
     2101 ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag atgatggcaa
     2161 cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg gagttggatg
     2221 ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg tcaagtcctg
     2281 tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc tacctacttt
     2341 atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt gatggtcgag
     2401 atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag acagagattg
     2461 gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat atcttgatag
     2521 aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa cgtaagggaa
     2581 ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac tatccactcc
     2641 cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga caaccagcct
     2701 tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac ttgtctgagt
     2761 ttggtaaggg ggttgccttt gtcaatgggc agaatctagg acgtttttgg aacgttggcc
     2821 caactctctc actttatatc cctcatagct atctcaagga aggtgccaac cgcatcatta
     2881 tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa cctacactaa
     2941 aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg gacgtttgat
     3001 ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca ttatggttgt
     3061 agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg cgacaccacc
     3121 aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc ttgctggcaa
     3181 atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc ttggtttggt
     3241 agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa caccagaaac
     3301 tcgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact tccacaaact
     3361 ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa tttcagactt
     3421 tttgagctta ttaaaatagg aaaaaatttt ttaggaggtc attgttatga tacaatggtg
     3481 gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt tgacgatcgt
     3541 ttcatctgca ggttcccctg tatttgctgg tttcattact ggtttaatca tgggagatgt
     3601 gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg ttggtacctt
     3661 cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag ccttctctgt
     3721 ttcacaagga attgatgcac cgcttgcaat tactacaatc gctgtaccag tagcagctct
     3781 cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc accgtgtgga
     3841 tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc ttggtgcgat
     3901 tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg gtggtgcctt
     3961 tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg gcttgacact
     4021 cgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc ttccagttaa
     4081 acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga ctgttcttta
     4141 ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc ttcctgctga
     4201 agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga ttggtatttc
     4261 tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag tagctgtagc
     4321 agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct aattacaaac
     4381 ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc caattaggtt
     4441 ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttgcct cagttgcgta
     4501 aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat actcaattct
     4561 tcaatacttc accattcttc cataccatta tcgctggttt tgaccttgcc atggaagaaa
     4621 aagatggtgt aggttcaaaa gacgctgtta acggtatcaa gacaggtttg atgggaccat
     4681 tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg gggtcagtcg
     4741 cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt gcagttgcag
     4801 tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa ggggttaacc
     4861 ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct gtacttggtg
     4921 tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct tacaagttgc
     4981 caatcggtga aaagatgatt gatttccaag acatcttgaa ccaaatcttc ccacgtttgc
     5041 ttccagcaat ctttactgcc tttatcttct ggttgcttgg taaaaaaggt atgaactcta
     5101 ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt ggtcactttg
     5161 cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat ggtcgcttct
     5221 gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac atttacacag
     5281 tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa gctgttattg
     5341 aaggattgga tgatttccta gtctttgcgg atcttctcgg tgggacacct tgtaatgtgg
     5401 tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg aatcttccaa
     5461 tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac aagagccgtg
     5521 ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg cttcgatgat gacgaagatg
     5581 aataatactc ttcgaaaatc tcttcaaact acgtcaacgt cgccttgccg taggtatatg
     5641 ttactgactt cgtcagtctt atccggcaac ctcaaagcgg tgctttgagc agcctgcggc
     5701 tagtttccta cagattttag ttggaactcg attcaattca tgtgacaacg tgaaaatcgt
     5761 tagagcattt tatatagaat atacatggga atggagctta ctcccattcc catatttaat
     5821 agaaaaagag gaactcaatg ctacattata caaaagaaga cttgctcgaa ttgggtgcag
     5881 aaatcactac gcgtgaaatc taccaacagc ctgatgtatg gagagaagct tttgaatttt
     5941 atcaagcaaa acgtgaagaa attgcagcct ttctacaaga aatcgctgat aaacatgact
     6001 atattaaggt tatcttgaca ggtgctggga cttctgctta tgtgggagat accttgctac
     6061 cttactttaa ggaagtctat gacgaacgca aatggaattt caatgctatt gcgacaacag
     6121 atatcgttgc caaaccagca acctatttga aaaaagatgt ggcaactgtc cttgtgtctt
     6181 ttgctcgtag tgggaactcg cctgaaagtg tggcgactgt tgatttggcc aaatccttgg
     6241 tggatgagct ttatcaagtg acgattactt gtgcaacaga tggtaaattg gctcttcaag
     6301 ctcacggtga tgaccgtaat ctcttgctct tgcaaccagc tgtctctaat gatgctggat
     6361 ttgccatgac ttctagcttt acgtctatga tgttgacagc tctcttggtc tttgatccta
     6421 cagaatttgc tgttaagtct gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt
     6481 tagacaaggt agaagatgtc aaagagctcg ttgatttaga ctttaaccgt gtcatctatc
     6541 taggcgctgg tcctttcttt ggacttgctc atgaagctca gctcaagatt ttggaattaa
     6601 ctgctggtca agttgcgacc atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat
     6661 ctcttatcaa cgacaataca gttgttttgg tctttggtac aacgacagcc tacactcgta
     6721 agtacgactt ggacttggtt cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc
     6781 ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga agtggtcctt ggttgtggcg
     6841 gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa ctctttgctc
     6901 tattgacttc actcaaggta gaaaataaac cagatacacc gtctcctaca ggtacagtaa
     6961 accgtgtagt acaaggtgtc ataattcacg aatatcaaaa gtaagacagt gtttatgaat
     7021 tcttgacaag aggatttgta aattatcaga taaaccatag attgtcagta cgctttctat
     7081 ggtttgtttg cttgagagaa atagtaaaag gagaacagaa tgaaagcata cacagagcgt
     7141 gtatttggaa atgttgaggg cgaggatgtc ttggcctatc gatttgagac agacggtggc
     7201 taccaacttg aggttatgac ttatggcgcg accatcttgc gctatgtcgc acctgacaag
     7261 gctggaaatt ttgccaatgt tatcttggga tttgatgact ttgatagtta tgtaggcaat
     7321 agtcccaagc atggagcaag tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt
     7381 gagctcaatg gtaagaccta tgaccttgag gttaataatg ctagcaactg taatcacagt
     7441 ggttcaactg gttgggattc cagcttgttt gaagttgaag aagtaagcga tcatggcttg
     7501 actctctaca cagagcgtac agatgggaca ggagggttcc ctggaaatct caagatttgg
     7561 atcagttatc acttggaaga aactggtgcc tatgaaatca tctacaaggt aacgaccgat
     7621 caggatacgc tggtcaatcc aaccaaccac agctatttca acttgtctgg tgatttcacg
     7681 cagacgattg accgtcatgt cttccaacta aacacagagg gcatttactc aatcgctcct
     7741 gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca catctacaat
     7801 ggtaccttgt tgaaggatat ctttgcagaa gaagatgagc aaatccagct ggcatcaggt
     7861 ttggatcacc catttgccct tcctgcaggc catgacaatg ctggattcct ttatgaccaa
     7921 aattcaggtc gcttcctgct tttcaagaca gaagctcctt gctttgtggt ctacacagca
     7981 aactttgtgg atgaaagtgt catcatagga ggtcagccaa tgctacagca caatgggatt
     8041 gctcttgaag cgcaagcttt accagatgcc attcacagtg accttaaagg ccaagtcatt
     8101 cttaaagctg gtcaaacctt caccagtaag acacgttatg aacttgttgt gaaataaaaa
     8161 aagctggtca aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt
     8221 gataatatgc gttttattat gaaatgattt actttatctt atcctgaaat ggtgttattt
     8281 ttgagttatc tggcttgact ttcttgatgg aaattatata atagttgtaa taacaataat
     8341 tacaacgaga aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca
     8401 gagacagttt taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt
     8461 ggtttagaaa tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc
     8521 ttggtacagc tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac
     8581 catttggcca ttctcttgcc cacacgcaag gctttggctg atgtcttgaa acacctgaca
     8641 gatttgcaaa ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg
     8701 gaagatttgg agggaaatgg cattgaactc tatcgagata agccagtttc cacatggaat
     8761 attcgagaag atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat
     8821 gagttggggg aaagagtaga gccctttatc ctggcagaag gtacaagaat ggggcatatt
     8881 catctttccg tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta
     8941 gagaataaat tcagtgtgcc tggcgctagt tggattgcgg ctggagatta ccatcatcat
     9001 ttagcagtta acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt
     9061 ttagcctact atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga
     9121 gcacaagaag ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac
     9181 tcagatggca tcgtgacccg tattcgttta gcaaggtaaa attaggaatt tttaataagt
     9241 tataagtatt gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga
     9301 tgggtgagaa ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg
     9361 aaaaagaaat gacaaattca aagtatatta cttgtttgaa acgttcagag ggccagttgt
     9421 gtggaattca aaagatgatt gaaggagatc gtgactgtgc tgatattgtg acgcaactga
     9481 cagcagtgaa atctagtgta gagcgcgtga ttgagatgat aattaccgaa aatcttactg
     9541 aatgtatcaa tcagccacta gatgattctg aagctcaaaa ggaacgccta gaaaaggcta
     9601 tccgatactt gattaaacgg aaataaatga atgttttgag acgatatgtg caaaggtcta
     9661 ttaactatta gaatagttta atgtgagtca aaagaagttg taaaaaatct ttaaaattaa
     9721 aaaacgcata gtatcaggta ttgaaatgta ctgcccccca aaagttagat tctttctgtc
     9781 taacttttgg ggggcagtac ataaaaacct tgatagtatg cgttttattg tggggagact
     9841 tatactcttc gaaaatctct tcaaaccacg tcagtttcac cttgccgtag atatggttac
     9901 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttc
//
LOCUS       DAVKUR010000063         9956 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKUR010000063 DAVKUR010000000
VERSION     DAVKUR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.063"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            269..364
                     /locus_tag="VW749_001837"
                     /pseudo
     CDS             269..364
                     /locus_tag="VW749_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(617..1237)
                     /locus_tag="VW749_001838"
     CDS             complement(617..1237)
                     /locus_tag="VW749_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0175828.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1237..1719)
                     /locus_tag="VW749_001839"
     CDS             complement(1237..1719)
                     /locus_tag="VW749_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0175829.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1719..2561)
                     /locus_tag="VW749_001840"
     CDS             complement(1719..2561)
                     /locus_tag="VW749_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0175830.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2656..3456)
                     /locus_tag="VW749_001841"
     CDS             complement(2656..3456)
                     /locus_tag="VW749_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0175831.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3600..4979
                     /gene="glmU"
                     /locus_tag="VW749_001842"
     CDS             3600..4979
                     /gene="glmU"
                     /locus_tag="VW749_001842"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0175832.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4989..5534
                     /locus_tag="VW749_001843"
     CDS             4989..5534
                     /locus_tag="VW749_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0175833.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5546..5860
                     /locus_tag="VW749_001844"
     CDS             5546..5860
                     /locus_tag="VW749_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0175834.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAAIFLLILLVLAMK
                     LL"
     gene            5877..6569
                     /locus_tag="VW749_001845"
     CDS             5877..6569
                     /locus_tag="VW749_001845"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0175835.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6646..7137
                     /gene="rocS"
                     /locus_tag="VW749_001846"
     CDS             6646..7137
                     /gene="rocS"
                     /locus_tag="VW749_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0175836.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7235..7825
                     /locus_tag="VW749_001847"
     CDS             7235..7825
                     /locus_tag="VW749_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0175837.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAD
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7834..9597
                     /locus_tag="VW749_001848"
     CDS             7834..9597
                     /locus_tag="VW749_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0175838.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9811..>9956
                     /locus_tag="VW749_001849"
     CDS             9811..>9956
                     /locus_tag="VW749_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0175839.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASYVFQISRNTIYGWLKLKEK
                     TGEL"
BASE COUNT         3084 a         1727 c         2116 g         3029 t
ORIGIN      
        1 ccccaaaagt tagatttttt ctgtctaact tttggggtgt agttcatgta cacctgatat
       61 gatgcgtttt ataattttaa agactttttg accagcctca tttttttaac ttgatactca
      121 gtgaaaagca aagattaaac taggaagcta gctgtaggct gctcaaagaa cagctttgag
      181 gttgcagata aaacttgtga ggtcaccaac atatataatg tgaagctgac gtggcttgaa
      241 tagattttag aagggtatga gtctggaagt tttaatggat aatgcaagat tccatagaat
      301 gggtaagcta gagttcttat gtgaagagtt tgggcataaa cttttacctt ttcctcccta
      361 ctcatcttag tatagaaaag tgaatctaaa atagtacata actgcttcta aaacattctt
      421 ataaattgat ttaaattctc aaatcatatt attcagttct tatttcattt tgctctacaa
      481 tcctgttgag aagacacgtg ttcatatcaa aaaggtattg gcaagttgca ataccttttt
      541 acaaggttct tttgtcttat ttttgtttca actgactata tctcctatgg ttctagttca
      601 gaaggctagg ctataattat gattgataag aagtatcatt ccaagtattg agagtgaatg
      661 tttcaaaatc atgggtttct ataatggtca ggctggcatt tgctagaccg ccatctttac
      721 gaagaagtgg ttctttatag cctaggagag tacgaagact ggcagtaaga ttggcgccgt
      781 gtccgacaat tagaatacgc tcagctggac tatcttttaa tgatttgata aattggatgg
      841 tccgttgagt tgtactatag agggattcgg ctccgaacat tcgagtgtca aattgagcaa
      901 gatttgaacg aaaagcctgg atttgttgcg ggtaaatagc ttccaaggtt gcaattttca
      961 aaccttctaa cttcccaagt tgccattcac ggagattagg aacgatttct aaagaacagg
     1021 gggtatagag ttgactttgg ataatctcag cagatttgac cgctcgaggt aaatcacttg
     1081 aataaatctg atcaaaagga atttccttga gatactggcc aagtcgtttt agggtttcaa
     1141 tggattcagg aagaagagga gaatcaccgc tagcaccttg aaaacgacct tcttggttcc
     1201 agagggtacg accgtggcgg acaaagtaga gtttcattac ttgatgtcct ccaaaatatc
     1261 tacaaagtct gcctttacaa agctagccaa gtcttgtggc gcgacgataa tgctgtgtcc
     1321 gacttcgcct gcagagacaa tcattcgatc caaatctaga gcaattttat cgataaaaat
     1381 gggataattg tgtttctgac gaattccgac aggattattg gctccatgaa tgtaaccagt
     1441 tgttttttct aagtcctttt gtggaatcat gctcactttt ttattgccag aaattttagc
     1501 tagtttcttt tcagacaagt gctgagtgat agggacaatt ccgataatcg gtccggtctt
     1561 gtctcccaaa agcgccaagg ttttgaaaat ctgatctcgt tcataacctt gaggaagctc
     1621 tccttctagg gcattgattt gaatcccctg atgagggata gctgctttag ataggatttg
     1681 ttccaccaat gtttttttga ttttaacttt ttttgccatt atttatattt atcctccaat
     1741 tgactcatcc aaataccaag ccagattccc agcgcaaaga agaaggcgat gatgacataa
     1801 ccgacaagtg aaagtcctgt gtattggata ctttcagcgt ttcctgcatt tggaattaag
     1861 atcaaaaggg tacttgatag gacgataccg atgatgaaat gatagacgcg tgagtggtag
     1921 ttgtttaagg cataatccat caattttgaa aaaacgatga gagttgcacc tgcaccaatt
     1981 ccaatcggaa agaaggttcc caagagatca aaagttttaa aaccagtcaa cataggagca
     2041 tagagtccca aaatcaaaag taagttcgat gggctgaggc caggaaccaa gacgccaagg
     2101 gccaatagtg cgcctgctag gacgaagtta agaaagctgg cgcttaaggt tccaacgaca
     2161 aaatttaagg catagagtcc taatccagaa atgataaagg ttgtccataa ccaagctaaa
     2221 tcaatcttgt ctcggtcaga ttctcgagtt gattctttga ggaggctagg aactgtaccg
     2281 ataatagctc ccgcaaagct ccataataca aagacctgat aattttcaag caggtattca
     2341 atcgggtagg aaaataagcc gattcccaga agcataccga tggcaactgg aataaagtac
     2401 aaaacatttt ctttaaggtc tttaaaggga tgggccagaa agccaatcat tcgttcatag
     2461 attcctaaga ttgctgctag aacccctccg gaaattcccg gtaggataaa tccaagagca
     2521 attacaatcc ctttaataac gcgtgctaac catgagagca tatatttcct ccaactattt
     2581 ctatttcaaa aaatccttac tatattgtat cacaatcaga cacaaaaaga aaaagcaaat
     2641 gataaacaaa tgcttttaag gttttaaaaa aagttttcga aaggtttctt ctttattttt
     2701 taagggagag ataacgttga tatctaaatc gtggtcaaag ccggcaattt ttcctttaga
     2761 tgtgtattgg tgaatatcat aatctaaatc agttttagga ctgctctcca aaaatcctga
     2821 gtctgagccg taggacggaa tccaaacaga ggtaaacttg cctgtatcaa tactgtgttc
     2881 ttccatgaag tagacaccaa cgtagatgcc gatgttttta gcacctagtg atgctagttt
     2941 tgctcgaaag ttttcgacac cttcgttcat attagacatg gttttgtctt ccacgtcaag
     3001 ccaatagtaa ctagggctgt aaggagaggc agcattgtag aaaacttcgg cagccttttc
     3061 catttcttgg acactttttc cagctacata agcgtagaca gcaactggga cattccgctt
     3121 ttgaagttca gtgatatgac tcttataggc cttgtctatt ccattgataa atgaagcatc
     3181 attttctttt gttgtttgag caccactgtg aacacgaaca atagcacctg aaatattttg
     3241 tgagagggca tcgtagttga tttcctcagg acgctgccag ccagagaggt caataatcgg
     3301 tttgtctaag tgtttcaaag cctgtgcttc aatctgtgct atattggatt ttgttttaaa
     3361 cgattggctg tcattaagtg ggcgattgat gattaaaatg aacatcataa tcccaaaaaa
     3421 actaaataaa ataagtggat gaatttgttt tctcatatct tataagtcta ccctaaaaat
     3481 caaaaaaaat caaaaaaatg ggttaaggaa gagactttag agcatttttt cattcaagag
     3541 tgcggaatga tttgaaatat ggtataataa aagggaattt ctacagaaaa gagaagatta
     3601 tgtcaaattt tgccattatt ttagcagcgg gtaaagggac tcgcatgaaa tctgatttgc
     3661 caaaagtttt gcacaaggtt gcgggtattt ctatgttgga acatgttttc cgtagtgtgg
     3721 gagctatcca acctgaaaag acagtaacag ttgtaggaca caaggcagaa ttggttgagg
     3781 aggtcttggc tggacagaca gaatttgtga ctcaatctga acagttggga actggtcatg
     3841 cagttatgat gacagaacct atcttagaag gtttgtcagg acacaccttg gtcattgcag
     3901 gagatactcc tttaatcact ggtgaaagct tgaaaaactt gattgatttc catatcaatc
     3961 ataaaaatgt ggccactatc ttgactgctg aaacggataa tccttttggc tatggacgaa
     4021 ttgttcgtaa tgacaatgct gaggttcttc gtattgttga gcagaaggat gctacagatt
     4081 ttgaaaagca aatcaaggaa atcaacactg gaacatacgt ctttgacaac gagcgtttgt
     4141 ttgaggcttt gaaaaatatc aataccaata acgctcaagg cgaatactat attacagacg
     4201 tcattggtat tttccgtgaa actggtgaaa aagttggcgc ttatactttg aaagattttg
     4261 atgaaagtct tggggtaaat gaccgtgtgg cgcttgcgac agctgagtca gttatgcgtc
     4321 gtcgcatcaa tcataaacac atggtcaacg gtgttagctt tgtcaatcca gaagcaactt
     4381 atatcgatat tgatgttgag attgctccgg aagttcaaat cgaagccaat gttaccttga
     4441 aagggcaaac gaaaattggt gctgagactg ttttgacaaa cggtacttat gtagtggaca
     4501 gcactatcgg agcaggagcg gtcattacca attctatgat tgaggaaagt agtgttgcag
     4561 acggtgtgac agtcggtcct tatgctcaca ttcgtccaaa ttcaagtctg ggtgcccaag
     4621 ttcatattgg taactttgtt gaggtgaaag gatcttcaat cggtgagaat accaaggctg
     4681 gtcatttgac ttatatcgga aactgtgaag tgggaagcaa cgttaatttc ggtgctggaa
     4741 ctattacagt caactatgac ggcaaaaaca aatacaagac agtcattgga gacaatgtct
     4801 ttgttggttc aaattcaacc attattgcac cagtagaact tggtgacaat tccctcgttg
     4861 gtgctggttc aactattact aaagacgtgc cagcagatgc tattgctatt ggtcgcggtc
     4921 gtcagatcaa taaagacgaa tatgcaacac gtcttcctca tcatcctaag aaccagtagg
     4981 agcctatcat ggagtttgaa gaaaaaacgc ttagccgaaa agaaatctat caaggaccaa
     5041 tatttaaact ggtccaagat caggttgaat taccagaagg caagggaact gcccgacggg
     5101 atttgatttt ccacaatggg gctgtctgtg ttttagcagt aacggatgaa caaaaactta
     5161 tcttggtcaa gcagtaccgc aaagctatcg aggctgtctc ttacgaaatt ccagccggaa
     5221 aattggaagt aggagaaaac acagcccctg tggcagctgc ccttcgtgaa ttagaggaag
     5281 aaacagccta tacagggaaa ttagaactct tgtacgattt ttattcagct attggctttt
     5341 gtaatgagaa gttaaaacta tatttagcaa gcgatttgac aaaagtggaa aatccgcgtc
     5401 cgcaggatga ggatgaaacc ttggaagtcc ttgaagtgag cttagaagaa gcgaaagaat
     5461 taatccaatc aggtcatatc tgtgatgcca agacaattat ggctgttcag tattgggagt
     5521 tgcagaaaaa atagaggagg tcagtatggg taaatcttta ttaacggatg aaatgattga
     5581 aagagctaat agaggcgaaa aaatttcagg tcctcctttg ctagatgata atgaggaaac
     5641 taagatttta ccaacctctt cttcccgttt tggttatgcc aatcctaagg atcatggttt
     5701 tagccaggaa accttgaaga ttcaggtcga accatctatt cataaaagcc gtcgtattga
     5761 aaataccaag agaaatgtct tcaattctaa gttgaataaa atcttatttg cggccatctt
     5821 tctcttgatt ttgcttgttt tagcaatgaa acttttgtaa tagaaaagga attgaaatga
     5881 aaataggaat tattgctgct atgccagaag aactggctta tctggtccag catttagata
     5941 atacccagga gcaagttgtt ttggggaata cctatcatac aggaaccatt gcttctcatg
     6001 aagtcgttct tgtagaaagt ggaattggta aggtcatgtc tgctatgagt gtggcgattt
     6061 tggctgatca tttccaggtg gatgccctta ttaatacggg ttcagctggg gcagtagcag
     6121 aaggtatcgc tgttggggat gtcgtgattg ctgacaaatt agcctatcat gacgtggatg
     6181 tcacagcttt tggctatgct tatggacaaa tggcgcaaca accgctttat ttcgaatcag
     6241 acaaaacctt tgttgctcaa atccaagaga gtttatctca attggaccaa aactggcatc
     6301 ttggtttgat tgctacagga gatagttttg ttgcaggaaa tgacaagata gaagcgatta
     6361 agtcccattt cccagaagtt ttagccgtgg agatggaggg ggcagctatt gctcaagcag
     6421 cgcatgccct caatctccca gtcttagtca tcagagctat gagtgacaat gccaaccatg
     6481 aagcaaacat cttttttgat gagtttatta tcgaagctgg acgtcgctct gcccaagtct
     6541 tgttgacctt tttgaaggct ttagattaag cggaaatttg acagtttttc tagcttatga
     6601 taagatttaa gtaaagaaaa gctagaaaac gtttcagagg atattatgag tattgaaatg
     6661 accgtcagtg agattgcaga ggtcttagga ttatctcgcc aagcaatcaa taaccgtgtc
     6721 aaagaattac cagaagaaga cacagataaa aatgacaaag gggtaacagt tgttaccaga
     6781 agtggcttga ttaagctaga agaaatctat aaaaaaacga tttttgaaga tgagcctgtc
     6841 agtgaagatg tcaaacaacg tgaactgatg gagattctag tggatgagaa gaatgcagaa
     6901 attcttcgtc tttatgaaca attaaaagcc aaggatcgtc agttatcaga aaaagacgag
     6961 cagatgcgta tcaaagaccg tcagattgct gagaaagaca aacaattaga tcagcaacaa
     7021 caattgaccc ttcaagccat gaaggatcaa gaaaatctta agctagagct ggaccaagca
     7081 aaagaagaag tccaatccac taagaaaggc ttttttgctc gtttatttgg aggataatca
     7141 aggagctgtt taggttaaat gctaacctga tggcttcttt tgtttgtgaa tagtatagtt
     7201 gattagaaca gagacagtag aggagaggta cagaatggaa cgattagaag attacattgc
     7261 ttttgactta gaatttaatc agcacgaagg acaaacacac ttgattcaag tatcggcagt
     7321 gcgttttaga gatggtcggg aaatcgatgc ctatgattcc tatgttcata ccagcgtccc
     7381 tctaaaaagc tttatcaatg gtttgaccgg gattacagct gagaccttaa aagatgctcc
     7441 tccagttgag aaagtcttag aagaattcca agagtttgtg ggttctttgc tgatgatagg
     7501 ctacaatgct gctaaaagtg atttacctat tttagcagat catggtttag actatagcca
     7561 acagtacaag gtggatttgt atgatgaagc ttttgaacgt cggagttcag atttacatgg
     7621 tattgccaat ctcaaattgc aaactgttgc ctcatttctt ggatttcaag gtcagtctca
     7681 taatagttta gaggatgctc ggatgacggc gcgtgtttac gaatccttct tagagtcgga
     7741 tcaagctagg gaattgttag agacagaaag tagcttatca aacaatcctt ttggtgtctt
     7801 ggacttgtct caattatttg actaggagtg cctatgaaac ctgaaaaacc taaaaaattg
     7861 ggtcttaaac agatttacct caatcttgat aaaatcctct ttctattttt cttgattttt
     7921 atgatagtgg agtatttgtg ggtaccattc aattcatggt tggctagctt cttattagat
     7981 cagacaggtt atctttttat ttcctataac aatgtcttag ccatccttac tcattctcca
     8041 ttgattagtc tagctttttt agccttgatt gtaattaacc ttctggttgc ttattttcaa
     8101 ataggactcc tctttattgg tgctcgtcat ctcctctata atgaaaagcg aaggctaatt
     8161 gagtatatcc gcaaggtttt ccatgaaagt tttggattta tgaaaaagct aacttgcgct
     8221 aaagccttgt ttatcttttt ctatatagct atgctttttc cttttatacg gaaaatgctg
     8281 aagatttatt atcttaataa aatcgtcatt ccagagttta tccaagctta tttagaagat
     8341 aaatattgga tgtggtggct gagcatccta cttctatctc ttatctttct ctatgtctct
     8401 gtcagattga tgtttgccct tccgaagatt gtatatgatc agctgactgt tcgagaagca
     8461 gtgatgttta gcttggagaa aaccaagaag agagttactt tttatgcttg gaatttattt
     8521 tacatcttgc tcaaagcaca tttattattt tatcttcctt tgattccttt attattggct
     8581 caaactttgg tagatgatat cactcagaga gagtctctga ttcttggtat tttgaatttt
     8641 gtcgtgatta aaaatctcta ttatatggct ctgacttatt ttttggttaa atttgtttca
     8701 tttttgacag gaaaggagct ggatatgctt cctaggagag aaaaagatca catcgtgcga
     8761 tggggtgtca tgacttgtgc cagtcttttc tttgccttag aaggttatat ttatctggag
     8821 gctcccatgg ttcatctacc tcaacttatt tctcaccgag gggtttccaa tgcaaatggg
     8881 attcaaaata cagtagagtc cttggaaact acagcacaac tcaaaccaga cttggtggag
     8941 acggacgtgc aggaaacaaa agatgggcag tttgtcatga tgcatgatgc taacttgaaa
     9001 aatctagcag gtatcaataa aagtcctcaa gacttaaact tggaggagct taaagggatt
     9061 gatatttttg aaaatggcta ccagactaaa atttcaagct ttgaagatta tctcagtcga
     9121 gccaacgaac ttggtcaaaa attactaatt gaaattaaaa ccagtaaaaa agatagtcca
     9181 gacatgatga accgcttttt agcccgttat gctgcaaagc tcaagattta tggacatcaa
     9241 atccagtctt tagactacca tgttgtcgaa aaagtaagac agtatgatgc cgaactgcca
     9301 gtttatttca tcatgcccta caattctgtc tttcctaaaa caagagcgac aggatatact
     9361 atggagtact caaccttgga tgaatatttt gtaagcaaac tatggacaac ggatcagaaa
     9421 ctttatgtct ggactgtcaa tgattcagaa gctatcagca aatctcttca cttaggagta
     9481 gatggagtga ttacagatga tttggaaaaa gttcagcggg aaatagaagt agcccaagaa
     9541 gatccagaat atacggattt gctcttgaaa aaagcattgg aattctttga attttagtaa
     9601 taaaaaagag gaacggttgt tcctcccatg ataggtaagt attcttgtga atgcttgctt
     9661 ttttgtggtt gcaatccgtt tacgagaatt gtttgtattg ttcttgtttc aatttacttt
     9721 atagtgcttt gaagttggaa tgctacacta taacttctaa aatatagtaa aatgaaccaa
     9781 aaatagtaca caatgtggta taatcttctt atggcatatt caatagattt tcgtaaaaaa
     9841 gttctctctt attgtgagcg aacaggtagt ataacagaag catcatacgt tttccaaatc
     9901 tcacgtaata ctatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaa
//
LOCUS       DAVKUR010000064         9815 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKUR010000064 DAVKUR010000000
VERSION     DAVKUR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.064"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            180..2108
                     /gene="glgB"
                     /locus_tag="VW749_001850"
     CDS             180..2108
                     /gene="glgB"
                     /locus_tag="VW749_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0175840.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRKDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATNITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2098..3240
                     /locus_tag="VW749_001851"
     CDS             2098..3240
                     /locus_tag="VW749_001851"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0175841.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3230..4369
                     /gene="glgD"
                     /locus_tag="VW749_001852"
     CDS             3230..4369
                     /gene="glgD"
                     /locus_tag="VW749_001852"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0175842.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4366..5799
                     /gene="glgA"
                     /locus_tag="VW749_001853"
     CDS             4366..5799
                     /gene="glgA"
                     /locus_tag="VW749_001853"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0175843.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5858..6229
                     /locus_tag="VW749_001854"
     CDS             5858..6229
                     /locus_tag="VW749_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0175844.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVPGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6269..6502
                     /locus_tag="VW749_001855"
     CDS             6269..6502
                     /locus_tag="VW749_001855"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0175845.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCSKEMLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            6511..7627
                     /locus_tag="VW749_001856"
                     /pseudo
     CDS             6511..7627
                     /locus_tag="VW749_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(7624..8070)
                     /locus_tag="VW749_001857"
     CDS             complement(7624..8070)
                     /locus_tag="VW749_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0175846.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8234..9538
                     /gene="eno"
                     /locus_tag="VW749_001858"
     CDS             8234..9538
                     /gene="eno"
                     /locus_tag="VW749_001858"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0175847.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
BASE COUNT         2947 a         1749 c         2170 g         2949 t
ORIGIN      
        1 tagaaaaaga aaggtgtttt cgcaattttt tgaaaaaata ttgatttaca attgaacgag
       61 taagtgaact tgttgtagat tttcaaaata attaaagaag tatagtaatt tacttgaatc
      121 ttctctaaaa aggtagtata ataaaaacat agaaaacgct tacaggagaa agggagtata
      181 tggataatag agaagcatta aaaaccttta tgacgggtga aaatttttat ctccaacatt
      241 atctaggagc acatagggaa gaactaaatg gagagtatgg ctataccttc cgtgtttggg
      301 cacctaatgc tcaggctgtt cacttggttg gtgattttac caattggatt gaaaatcaga
      361 ttccaatggt aagaaaggac tttggggtct gggaagtctt taccaatatg gctcaagaag
      421 ggcatattta caaatatcat gtcacacgtc aaaatggtca tcaactgatg aagattgacc
      481 cttttgctgt caggtatgag gctcgtccag gaacaggggc aatcgtaaca gagcttcctg
      541 ataagaaatg gagggatgga ctttggctgg cacgaagaaa acgttggggc tttgctgaac
      601 gtcctgtcaa tatttacgag gttcatgctg gctcttggaa gagaaatcct gatggcagtc
      661 cttatagttt tgcccaattg aaagatgaac tcattcctta cctagttgag atgaactata
      721 ctcatattga gtttatgccc ttgatgtccc acccactagg tttgagttgg gggtaccagc
      781 ttatgggtta cttcgcttta gagcatgcct atggtagacc agaggagttt caagattttg
      841 tcgaggagtg tcatacccat aatattgggg ttattgtgga ctgggtacca ggtcacttta
      901 ccatcaatga tgatgcctta gcctattatg atgggacacc gacttttgaa taccaagacc
      961 ataataaggc tcataaccat ggttggggtg cccttaattt tgaccttgga aaaaatgaag
     1021 tccagtcctt cttaatttct tgcattaagc attggattga tgtctatcat ttggatggta
     1081 ttcgtgtgga tgctgttagc aacatgctct atttggacta tgatgatgct ccatggacac
     1141 ctaataaaga tggcggaaat ctcaactatg aaggttatta tttccttcag cgcttgaatg
     1201 aggttattaa gttagaatat ccagatgtga tgatgattgc agaagaaagt tcgtctgcga
     1261 ccaatattac gggaatgaaa gagattggtg gtctaggatt tgactacaaa tggaacatgg
     1321 gctggatgaa tgatatcctc cgtttctacg aagaagatcc gatctatcgt aagtatgact
     1381 ttaacctggt gactttcagc tttatgtatg ttttcaagga gaattatctc ttgccattct
     1441 cgcacgatga agtggttcat ggcaagaaga gtatgatgca taagatgtgg ggagatcgtt
     1501 acaatcaatt cgcaggcttg cgcaatctct atacgtacca aatttgtcac cctggtaaga
     1561 aattgctctt catgggtagc gaatacggtc aattcctaga atggaaatct gaagaacagt
     1621 tggaatggtc taacctagaa gacccaatga atgctaagat gaagtatttc acttctcagc
     1681 taaaccagtt ttacaaagat catcgctgtc tgtgggaaat tgataccagc tatgatggta
     1741 ttgaaatcat tgatgcggat aatcgagacc agagtgttct ttcctttatt cgtaagggta
     1801 aaaagggaga aatgttagtc tgtatcttta atatggtacc tgttgagcgg aaagatttta
     1861 caatcggact acccgttgca ggaatttacg aagaagtatg gaatactgag ttggaagagt
     1921 ggggaggcgt ttggaaagaa cataatcaaa ctgttcaaac gcaagaagga ctatggaaag
     1981 attatgagca gaccttaacc tttaccctac cggctatggg agcaagtgta tggaaaatca
     2041 aacgtcgctt gaaatctact aaaaccgtca caaataaaaa ccaaaaagga gtagaaaatg
     2101 aaaaatgaaa tgttagcttt gattcttgct ggtgggcaag gaactcgtct cgctaaactc
     2161 actcaaagca tcgcaaaacc agctgtgcaa tttggtgggc gctaccgtat cattgacttt
     2221 gccctatcaa actgtgccaa ctcagggatt cacaatgttg gggtcgttac acagtatcaa
     2281 ccacttgctc tcaacaacca tattgggaat ggttcaagct ggggactaga cggtattgat
     2341 tcaggtgtct ctattcttca accttattct gcaagtgaag gaaatcgttg gtttgagggg
     2401 actagtcacg ctatttacca aaatatcgac tatatcgaca gtgtcaatcc tgagtatgtc
     2461 ttgattttgt ctggggatca catctacaaa atggactatg atgatatgct ccagtctcat
     2521 aaggataata atgccagctt gacagtagca gttttagacg tccctcttaa agaagcaagc
     2581 cgttttggta tcatgaacac agatgctaac aatcgtattg ttgaatttga agaaaaacca
     2641 gctcaaccta aatctacaaa agcttctatg ggaatctaca tttttgattg gcaacgcctt
     2701 cgtaatatgt tagtcgctgc tgaaaagagc aaggttggca tgtcagactt tggtaaaaat
     2761 gtcattccaa attaccttga gttaggtgaa agtgtttatg cttacgaatt tagtggttat
     2821 tggaaagatg ttggtactat tgagtcactt tgggaagcga acatggagta tatttctcca
     2881 gaaaatgcct tggatagtcg taaccgtcaa tggaagattt actcaagaaa cttgatttca
     2941 ccaccaaact tcctcggggc aaatgctcat gtggaagact cattagttgt agacggatgt
     3001 ttcgttgatg gaactgttaa acattctatc ctttcaacag gcgcgcaagt tcgcgaagga
     3061 gcggaagtcc ttgattcagt tatcatgagt ggagctatca ttggtcaagg agctaagatt
     3121 aaacgtgcca ttattggtga aggtgcgatt atttctgacg gtgtcgaaat tgatggaaca
     3181 gatgaagtac aagttgtagg atataatgaa gtagtggggg tagcaacaga tgaagattga
     3241 taaatattct gccattttag gaaatacagt tggttttcac aatatgtcga cattgacgga
     3301 ccaccgtcca gtagcaagtt tgccatttgg tgggaaatat cgtttgattg atttcccact
     3361 ttcaagcctt gctaatgcag gtgttcgtag tgtctttggt attttccagc aggataatat
     3421 cagctcagta tttgaccata ttcgttcagg acgcgagtgg ggcttatcaa cccttcttag
     3481 ccattactat ctaggaattt acaatacccg tgtagaaagt agtacagttg gaaaagaata
     3541 ctaccaacag cttcttactt atttgaaacg ttctggctca aaccaaacgg ttgccctcaa
     3601 ctgcgatgtt cttattaaca ttgatttgaa ccaagttttc cacctacata gtacaacaaa
     3661 agagcctatc actgtagttt ataaaaaact agctaagaaa gatatttcag aagtaaatgc
     3721 aatcttggat gtagatgaaa cagaccatgt tctttctcat aaactctttg atagcaagtc
     3781 aacagctgaa acgttcaata tgtctacaga tatctttgtc gttgatacac cttggttgat
     3841 tgaacacttg gaagaagaag ctaaaaaaga acatccagag aaattgcgct atgttttacg
     3901 ggatttggct gtaaaagagg gagctttcgc ctacgagtac acgggctatc tagccaatat
     3961 tcactctgtt aaatcttatt atcaagcgaa tatcgatatg cttgaatcac aaaaattcta
     4021 ttctcttttc tcaccaaacc aaaagattta tacaaaggtc aaaaacgaag agccaactta
     4081 ctatgctaat acatctaagg taagcacttc tcagtttgcc tctggtagta ttattgaagg
     4141 tcaagtagct aattctgttc tatcacgtaa tattcatgtc cataaggata gcttggttaa
     4201 agatagcctg ctcttccctc gtgttgttat tggagaaggg gctcaggtcg aatatgctat
     4261 cttggacaaa ggggttgaag ttgagcctgg tgttgtgatt cgaggaactg cagaacatcc
     4321 agttgtggtt aagaaaggtg ctaaagtaac agaggatatt cattcatgaa aattttattt
     4381 gtagcagcag agggtgcacc cttttcaaaa acaggtggtt tgggagacgt cattggcgct
     4441 cttccaaaat cactggtaaa agctgggcac gaagttgcag tgattttacc ctactatgat
     4501 atggtagagg ctaaatttgg aaatcagatt gaagatgtgc ttcattttga ggtgagcgtt
     4561 ggttggcgca gacagtattg tggaattaag aaaacagtat taaatggtgt aaccttctac
     4621 tttattgaca atcaatatta tttcttccgt ggtcatgttt acggtgattt tgatgacgga
     4681 gaacgctttg cctttttcca actggctgcc attgaggcta tggaaaggat tgactttatt
     4741 cctgatcttc tccatgttca tgactaccat acagctatga ttcctttctt gttgaaggaa
     4801 aaataccgtt ggattcaagc ctatgaggac attgaaacag ttttaaccat tcataattta
     4861 gaattccaag gacaattttc agaaggaatg ttgggtgatt tgtttggagt tggctttgaa
     4921 cgttacgctg atggcaccct tcgatggaac aactgtctga actggatgaa ggcaggtatt
     4981 ctctatgcga accgtgtttc aaccgtttca cctagctatg ctcatgaaat tatgactagt
     5041 cagtttggat gtaatttgga tcagattctt aaaatggagt ctggtaaagt atctggtatc
     5101 gtgaatggga ttgatgctga tctttataat cctcagacgg atgctctttt agactatcat
     5161 ttcaatcagg aagatttgtc tgggaaagcc aaaaataagg caaaattgca agaaagagtt
     5221 ggcttgcctg ttagagcaga cgttccactg gtgggaattg tttctcgttt gacacgtcaa
     5281 aaaggttttg atgtggtggt cgaaagtctt caccatatct tgcaagaaga tgttcagatt
     5341 gttcttttgg gaactggcga tccagccttt gaaggagctt tctcatggtt tgctcagatt
     5401 tacccagaca agctatcaac aaatatcact tttgatgtca aacttgctca ggaaatctac
     5461 gctgcttgtg acctcttcct catgccaagt cgttttgaac cgtgtggctt gtctcaaatg
     5521 atggctatgc gttatggaac cttgccattg gtccatgaag ttggaggctt gcgagataca
     5581 gttcgcgctt tcaatccaat cgaaggaagc ggtactggct ttagctttga caatctatct
     5641 ccttattggt taaattggac tttccaaaca gcattggact tgtatagaaa ccatccagac
     5701 atttggagaa acctacaaaa acaagctatg gagagtgact tctcatggga tacagcctgc
     5761 aagtcatacc ttgacttgta ccatagttta gttaattaat agataaaatc gtatgatgac
     5821 ttcatacgat ttttaggctg tttagagagg agaactgatg tctcaagtaa aaggcttgtg
     5881 tgttttggat gtagatggaa ccttaatcct agaagaagtg attgatcttt tagggagaga
     5941 ggcaggtcat gaggcggaaa tttcgcagat tacaagtcga gcaatgcgag gagagttggt
     6001 ctttgaaagc agtttaagaa aaagagtgtc cttgttggaa ggtcttccta ttttggtctt
     6061 tgataacgtc ttcaactcaa ttcatctatc gctaaatgtc ccagagttca tctctattct
     6121 ccaaaagaat ggcatcctag ttggtctggt gcctggtgga tttacaccaa tagttggaga
     6181 gattagcaaa atcccttggt attgcctatt tcactgccaa ccagcttgaa gtcaaagaag
     6241 gtttttaaca ggaaaattag ttggacaaat tataagtccc caggtcaaaa aagaaactct
     6301 ggaaaaatgg agaaagaaac taaaactttc taaagaaaga acggtggcaa tcggtgatgg
     6361 ggtcaataat ctattaatgt tgaagtcggc ggagttagga atcgcctttt gttccaaaga
     6421 aatgctcaaa aaagaaatac cacatcatgt tgacaagagg gattttttag aagttcttcc
     6481 tttgattgac tgtttagaat gagggaaaat atgaagattg taattgcacc ggattcgttt
     6541 aaggaaagct tgacagctca acaggtagct gaagcaataa aaagaggctt ccaacaatcg
     6601 atagcagatg tagaatatct cctctgccct gttggtgatg ggggagaagg tactgtagat
     6661 gctatccgac attctcttga cctaaaagaa aaatggatcc aagtgacaga cccttttgga
     6721 caaaaagaag ccatgcgcta ttttcaaaaa ggggaactgg cactatttga agtagctgac
     6781 ttggttggtc ttggaaaaat tccgctagag aaacgaaatc cacttcaaat ccaaacttgt
     6841 ggtattggag agttgattct ccatctcatt tctaaaggga ttaaagatat ttatatcggt
     6901 gttggtagca cggccagtaa tgatggagga ctggggattg ctgctggttt aggttatcaa
     6961 ttttatgata gggatggaaa tgtcttgcct gcttccagtc aatccttatt aaacttagct
     7021 tctgtttcaa cagaaaattg ctataaaatt cctgaaggtg ttcaaattca tattctagca
     7081 gatgtcgtga gtcccttatg tggtcatcaa ggtgcgactt acacttttgg caatcaaaaa
     7141 ggtctacatc cgactatgtt tgcagtcgta gatcaggcga tccaagattt ttatgaaaaa
     7201 ttctcacctg caacattaga aattaaagga gcaggagcag gtggaggcct tgctggtggt
     7261 ttgtgtgcct ttgctcaggc aagtatcgtg tctggaattg ataccttgct tggacttaat
     7321 caactttgat aagaaagttt cagatgctga cttgcttgtt gttggagaag gaagacttga
     7381 cagtcaaagc tttgctggga aagcgcctat aggtgttgca aaaagaaccc ctgttggagt
     7441 tcctgttatt gctatttgcg gtagtcttgc tgaagattta cctcccctac catttgaaaa
     7501 tatccaagct gtcttttcta ttttggagaa aagtgaacct ttagaagata gtttgaaaaa
     7561 tgccagtctc tatctggagc gcacggctgc caatattggg cacttattaa atatgtgcaa
     7621 gatttagcta aaccatttct tccataagga tgttttggct ggttcttcct ttttaacttc
     7681 ccaaagtttt ggaaaagcaa gtcgaaggtc tttttcttct acttgaactg gtgcattgct
     7741 atgaataacc aggccaaaag gagaagtaat atgctcttca gatactatgg tggcttgact
     7801 atcagtttct tttgcttctt ttaagtagaa aacttgctta tcaaattcga tagttggtga
     7861 aatcttcaca aatagtggct ctgctttttc ctgaaggttt tctaaaataa ataaaaagcc
     7921 tttttctaac tgagggctat ttgctgtgtc aatatctaca tatccaagaa ctctttcctc
     7981 aaaagtacca agatagcgtc tttgctcatc cggatttatt tttaacccac catgagcttt
     8041 ttcaagtaat tgttttgata aatctgtcat gaaaacagta tatcataaaa gttagaataa
     8101 aacagacaaa agaaagcgat tactttataa agttaaggaa aagttgcaca aagataacgt
     8161 tttttcttga aaaaggaggg gttttaaggt attatagagg tgtaaaaaat ttaactcata
     8221 aggagagtaa aaaatgtcaa ttattactga tgtttacgct cgcgaagtcc tagactcacg
     8281 cggtaaccca acacttgaag tagaagttta cactgaatca ggtgctttcg gacgtggtat
     8341 ggttccatca ggagcttcta ctggtgaaca cgaagcagtt gaacttcgcg acggtgacaa
     8401 atctcgttac ggtggtcttg gtacacaaaa agctgttgac aacgtaaaca acatcattgc
     8461 tgaagctatc attggctacg atgtacgtga tcaacaagct attgaccgtg ctatgatcgc
     8521 acttgacggt actcctaaca aaggtaaatt gggtgcgaat gcaatcctcg gtgtgtctat
     8581 cgctgtagct cgtgctgctg ctgactacct tgaaatccca ctttacagct accttggtgg
     8641 attcaacact aaagttcttc caactccaat gatgaacatc atcaacggtg gttctcactc
     8701 tgacgctcca atcgctttcc aagagttcat gatcttgcca gttggtgcgc caacatttaa
     8761 agaagccctt cgttacggtg ctgaaatctt ccacgctctt aagaaaatcc ttaaatcacg
     8821 tggtttggaa actgccgtag gtgacgaagg tggattcgct cctcgtttcg aaggaactga
     8881 agatggtgtt gaaactatcc ttgctgcgat tgaagctgct ggatatgtac caggtaaaga
     8941 cgtatttctc ggatttgact gtgcttcatc agaattctac gataaagaac gtaaagttta
     9001 cgactacact aaatttgaag gcgaaggtgc tgctgttcgt acatctgcag aacaaatcga
     9061 ctaccttgaa gaattggtta acaaataccc aatcatcact attgaagatg gtatggatga
     9121 aaacgactgg gatggttgga aagctcttac tgaacgtctt ggtaagaaag tacaacttgt
     9181 tggtgacgac ttcttcgtaa caaacactga ctaccttgca cgtggtatcc aagaaggtgc
     9241 tgctaactca atccttatca aagttaacca aatcggtact cttactgaaa cttttgaagc
     9301 tatcgaaatg gctaaagaag ctggttacac tgctgttgta tcacaccgtt caggtgaaac
     9361 tgaagattca acaatcgctg atatcgcagt tgcaactaac gcaggacaaa tcaagactgg
     9421 ttcactttca cgtacagacc gtatcgctaa atacaaccaa ttgcttcgta tcgaagacca
     9481 acttggtgaa gtagctgaat atcgtggatt gaaatcattc tacaacctta aaaaataaaa
     9541 tagttcagtg aactatttta tcccgaacca tgaaattcaa aagttcggcc gttgatttaa
     9601 caacgtttct agcccctcgg attttatccg aagggctatt tttgtattta gagggcaaaa
     9661 aagggacaaa actttttggc tctttgtcaa ctgtagtggg ttgaagtcag ctaagctcga
     9721 gaaaggacaa aattcgtcct ttcttttttg atgttcagag cgataaaaat ccgttttttg
     9781 aagttttcaa agttccgaaa accaaaggca ttgcg
//
LOCUS       DAVKUR010000065         9457 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKUR010000065 DAVKUR010000000
VERSION     DAVKUR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.065"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..183
                     /locus_tag="VW749_001859"
     CDS             <1..183
                     /locus_tag="VW749_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0175848.1"
                     /translation="EYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSG
                     VTLITGKNGTGKSTLL"
     gene            complement(549..1859)
                     /locus_tag="VW749_001860"
     CDS             complement(549..1859)
                     /locus_tag="VW749_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0175849.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALKLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2096..2968
                     /locus_tag="VW749_001861"
     CDS             2096..2968
                     /locus_tag="VW749_001861"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0175850.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3099..3930
                     /locus_tag="VW749_001862"
                     /pseudo
     CDS             3099..3930
                     /locus_tag="VW749_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            4041..4967
                     /locus_tag="VW749_001863"
     CDS             4041..4967
                     /locus_tag="VW749_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0175851.1"
                     /translation="MDLSQTMPSYAQVVSLYDDTSISVSNNETDKVLAGSLYTDTNEQ
                     GLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQFQTKIVRVINDE
                     DDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQKNKKYTVLS
                     QQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIGVMKAVGYQ
                     NRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFELNLLSVLG
                     TLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            5144..6151
                     /gene="gap"
                     /locus_tag="VW749_001864"
     CDS             5144..6151
                     /gene="gap"
                     /locus_tag="VW749_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0175852.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6218..7054)
                     /locus_tag="VW749_001865"
     CDS             complement(6218..7054)
                     /locus_tag="VW749_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0175853.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            7180..9375
                     /locus_tag="VW749_001866"
     CDS             7180..9375
                     /locus_tag="VW749_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0175854.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
BASE COUNT         2919 a         1660 c         2074 g         2804 t
ORIGIN      
        1 gagtatgaaa acagaacggt ttcttttgct attagttcaa aaggagaaaa aatgaaagta
       61 gaaaatattt cgtatagggt ggatcatcgt atattgtttg ataatatttc ttttgatact
      121 tcgagttcag gcgtgacatt aattactggt aaaaatggta caggaaagtc aactttacta
      181 tagtagattg aaactagaat agtacacatc tacttctaaa atattgttag aaatcgattt
      241 gactatcctg atctatttgt cctgttctta tttcatttca ctacatctca aattgagtat
      301 gacgaagtgc gctcccatgt cctgggaacg cactttcttc atatttttca tattcttgaa
      361 tccatcgata aagactattg ggatgaattt ttaaagttga actaattatt tttacaggat
      421 gaggtttaca gcagagagtt tgaaggcttt atcaaaggtt tttcttggca taatgacttt
      481 tcctcgtttc cacttaattt tgtgtctact ttattatacc aagtccaccc ttaagttaga
      541 taatgaatct aacttaagga agctagaagg atgagaatcc aggtggtcaa gagtcccaaa
      601 cttaagctga tagggacacc cagaataatt tgctttttga aggcaagacc gcgttcctct
      661 atattgggaa gtgagagttg aatgagagaa ccagctgatg aaaagggtga gatattagta
      721 gatagagcgc caataacggt ggctgttgtg agtaagtgaa tatcaatctg aggattttga
      781 gcactgatga tagcaatgat gggaaagagg gctggagcta caacggatag ggtggaacta
      841 aagagtgaca tcactccggc tatcacacaa aagaacagag gtaaccagaa atgaggaatg
      901 gttgttgtca tgaggtgccc tatcagtgtg actaaacctg acttgaccgc tagagacatt
      961 agtaagctca tgccgcagag catgataatt gtagcccagg gaaccttagc taaaatggct
     1021 tcttgcttcc ctaatttgag ctttaaggcg aggcagacca tgagtattga gacaaagcca
     1081 atatcaaatg ttttttgata agtagctatc caggcgatgt ttgggaaaat gagatgcaac
     1141 aagggaaaaa gccaaaccaa aaccatgctg ctgatcatga gcaaggtggt ttgtctttga
     1201 accttgctga ggagtggtgg ttggtcaata gtcaaggatg agtttgttct tcccttacta
     1261 tagtgactgt aacaggataa taaaagcaag acgatgagtg ggtagataat gctgacgata
     1321 aagatatgat tgccaagtga aaaagcttgc tcttcccatc ccatttgctt aaacaggcct
     1381 tgaaagacaa tgcctgagct actggttatc aaattagccc ctcctgaagc tccccaattg
     1441 acggcttgag ctccaatcaa agggtgtttg tccgcttttt gacagagggt aatcgctaga
     1501 ggacagcaaa cggccatagt agtgaaaaat ccagcaccta aagcagacaa aagggttgcc
     1561 atcaggtata aaatcatgta gagggcgtta gggtgggtgc gtgtgcggta gagaatgtgt
     1621 tgagccaaaa catcaagagt accgttagtt gttgcaacgt tataaaagag agagacgcta
     1681 aaaatggtaa aaaagagtga ggttggccaa aaatgaagaa gttctttggg gcttaatccc
     1741 atgagagtgg ttgcgatgag gtaagaaaaa gcaatagcca gcaggccaat attgattttg
     1801 gtgcggtaac caattccaat ggctagagca atggcgctaa tcattattaa atgaatcatt
     1861 gaattgtcct ttcagttaga atatggaaat aggttggcaa ttttggcgct caaaagacca
     1921 cctgtttcct attggtactt gactattata cacaaaaaaa atacaattgt cttgacaatt
     1981 gtattgacac ttgttagaat taaaaatgag gtattcaggc ttgtgatttc ctatggaagt
     2041 taatagtaat tgcctctagt gcttacaagt gatattaaaa atagaggact tagtgatgtc
     2101 aatcatttca actgatttaa ccccttttca aatagatgat acattgaaag cagccttgcg
     2161 agaagatgtt cattccgaag attacagtac caatgccatt tttgatcatc atggccaagc
     2221 taaggtgtcg ctttttgcca aggaagctgg tgttttagcg gggctaaccg tttttcaaag
     2281 ggtttttacc ctatttgatg ccgaggtgac cttccagaat cctcatcaat ttaaggatgg
     2341 ggatcgtttg actagtggcg atttggtttt agaaatcata ggctcggtga gaagtctctt
     2401 aacatgtgaa cgcgttgcct tgaatttttt acaacattta tcagggattg cttcgatgac
     2461 agctgcttat gtagaagcct taggcgatga ttgcattaag gtatttgata ctcgaaaaac
     2521 tactcctaat ttacgtcttt ttgagaaata tgccgtgaga gttggcggtg gctataatca
     2581 tcgctttaat ttatcagatg ctatcatgct aaaagacaat cacattgcgg cagtaggtag
     2641 tgttcaaaag gcaattgctc aagcgcgtgc ctatgcccct tttgtgaaaa tggtcgaggt
     2701 ggaagtggaa agccttgctg ctgccgaaga agctgcggcg gcgggtgctg atattatcat
     2761 gttggataat atgtcattgg aacagattga acaggccatt accctaattg caggacgttc
     2821 tcggattgaa tgttctggaa atattgatat gaccactatt agccgttttc gtggtttagc
     2881 gattgattac gtctccagtg gtagtttaac ccatagtgct aagagtcttg atttttccat
     2941 gaaggggtta acctaccttg atgtctaagt tgtaaaataa actaactttt taaaggatgt
     3001 ctttcctcta gaacgagttt tatgtcagat agtttaaacg cctcttcaaa tatagtaaaa
     3061 tgaaccaaaa atagtacaca atgtggtata atctttttat ggcatattca atagattttc
     3121 gtaaaaaagt tctctcttat tgtgagcgaa caggtagtat aacagaagca tcacacgttt
     3181 tccaaatctc acgtaatacc atttatggct ggttaaagct aaaagagaaa acaggagagc
     3241 taaaccacca agtaaaagga acaaaaccaa gaaaggttga tagagataga cttaaaaact
     3301 atcttactga caatccagac gcttatttga ctgaaatagc ttctgaattt ggctgtcatc
     3361 caactaccat ccactatgca ctcaaagcta tgggctacac tcgaaaaaaa gaaccacacc
     3421 tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa tagtttaaag
     3481 cacctatcac ctgtttagat tgatgaaaca ggatttgata cttattttta tcgagaatat
     3541 ggtcgctctt taaaaggtca gttaagaaga agatatcaga ggatttcttt ggttgcaggt
     3601 ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga
     3661 cttttttgaa gcatggtttc agaagtttct cttaccaaca ttaaccacac catcggttat
     3721 tattatggat aatgcaagat tccatagaat gggtaagtta gaactcttgt gtgaagagtt
     3781 tgggcataaa cttttacctc ttcctcccta ctcacctgag tacaatctat tgagaaaaca
     3841 tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac cttttacgag
     3901 gcttttttat cctgctcttg tttcaattga ctatagttca cggatacagt tgggaaagaa
     3961 gctattaaat atttggagag tccttttggg atgaacatgt caaatattac tatagatggg
     4021 caagaaaaga tgggcaagaa atggatctga gtcaaacgat gccttcttat gctcaagtag
     4081 tgagtcttta tgatgataca agtatctctg ttagtaataa tgagacggac aaagtgttgg
     4141 ctggctccct ctatactgat acaaatgaac agggattaac gattccaagc agtttactaa
     4201 aaaattggaa tgaacagaca ggaaaaaatt tgacagctaa tgatcttatt ggcaaatcag
     4261 tctcagccag cattgtagaa agtgctgccg aaactagtaa gattgctcaa tttcaaacga
     4321 agattgtacg tgtaatcaat gatgaagatg acatggagga cagcaacagt ttcatgctgt
     4381 ctcatcaaat ggaaacgatt ttgaaagagg ctggatttac gaaagctgta tcttatttta
     4441 tcttggaact caaagatcca tcacagacaa aagtagtaac agaagaatta cagaaaaata
     4501 agaagtatac tgtgctttct caacagagag ttcttgatat tgtgattacc tttattcgtg
     4561 ttattcaggg attattgatt gtgctttcat cacaagctat tgtggtagca gcggttatga
     4621 ttggtatcat tatttacatc aatatcatgc aacgttccaa ggaaataggt gtcatgaaag
     4681 cagttggtta tcagaatcgt ggtgtcaaag gaatttttat ttacgaggct atctggattg
     4741 taggcatcgc cttgctgctg gcatttttgg ttgcacaagg ggtgggaagt ttggcgaatg
     4801 cgattgtaag tcacttttac ccatccatca ctaaggtttt tgaattaaat cttttatctg
     4861 ttttaggaac tctagttttc gctctattac ttggttatgt ctcagcctac ttcccggcgc
     4921 gtaagattag taaaatggat cctgtagaat cgttacgcta tgaataataa gggattcctt
     4981 gatttacagt cttaaaaaga aactcacata gaaaaacaat ggccatactt gcaattcaac
     5041 tcaaatagtt gtataatagg tttgttgaaa ggtgatttgt agtgattcaa gttactcttt
     5101 tcacaataaa aatttcatga ttttcataag gaggaaatca ctaatggtag ttaaagttgg
     5161 tattaacggt ttcggacgta tcggtcgtct tgctttccgt cgtatccaaa acgtagaagg
     5221 tgttgaagtt acacgcatca acgaccttac agatccagtt atgcttgcac acttgttgaa
     5281 atacgacaca actcaaggtc gtttcgacgg tactgttgaa gttaaagaag gtggattcga
     5341 agttaacggt aaattcgtta aagtttctgc tgaacgtgat ccagagcaaa tcgactgggc
     5401 tactgacggt gtagaaatcg ttcttgaagc tactggtttc tttgctaaga aagaagcagc
     5461 tgaaaaacac cttaaaggtg gagctaaaaa agttgttatc actgctcctg gtggaaacga
     5521 cgttaaaaca gttgtattca acactaacca cgacgttctt gacggtactg aaacagttat
     5581 ctcaggtgct tcatgtacta caaactgctt ggctccaatg gctaaagctc ttcaagataa
     5641 ctttggtgtt gttgaaggat tgatgactac tatccacgct tacactggtg accaaatgat
     5701 ccttgacgga ccacaccgtg gtggtgacct tcgccgtgct cgcgctggtg ctgcaaacat
     5761 cgttcctaac tcaactggtg ctgctaaagc tatcggtctt gtaatcccag aattgaacgg
     5821 taaacttgac ggatctgcac aacgcgttcc aactccaact ggatcagtta ctgaattggt
     5881 agcagttctt gaaaagaacg ttactgttga tgaagtgaac gcagctatga aagcagcttc
     5941 aaacgaatca tacggttaca cagaagatcc aatcgtatct tcagatatcg taggtatgtc
     6001 ttacggttca ttgtttgacg caactcaaac taaagttctt gacgttgacg gtaaacaatt
     6061 ggttaaagtt gtatcatggt acgacaacga aatgtcatac actgcacaac ttgttcgtac
     6121 tcttgaatac ttcgcaaaaa ttgctaaata attcttgagt tgatagaaag caaggctttg
     6181 tggtcttgct ttttatatgg aaaaatggat gacacgatca tccattcttt tttaattctt
     6241 tttcaaatgt atttgaaagg gtagtgaaag ttagcttctc taaagtaagt gggtgggtaa
     6301 aggaaagtcg gaaggcatga agcataagcc ggcttgtctt tgatttacta ttatagagag
     6361 ggtctcccag gataggaaga ttatgatgcg aaaggtgcac acgaatctga tgggttcgcc
     6421 ctgtctttag cttgcaatga gccaaggaag tcttgtttga gaattgcttt aatctgctta
     6481 catgcgtttc agcatattgc ccattttttg catcaactat tctttttcta cgatcatggc
     6541 gatcacgtcc aattttgtct ctgaaaacaa gttcttttct gttgatattt ccatcaacta
     6601 gagcccaata ttctctagaa atctcttttt tctccaataa gcgattgaga atgggcagga
     6661 taaaaggatt tttggcaaag agaactaagc cactggtttc catgtccaga cgatgaacga
     6721 catagcaggt ttggccaaca taggtactga catggttaag aagggcaatt tcgtttggtt
     6781 gattaccatg cgttttcatc ccctctggtt tgtttacaat aatcaagtgt tgatcttgat
     6841 aaacttcctg cactaagtct gggttgcccc aagggatcgt cttttgggaa taatcttcct
     6901 cgtcaaaagt caactggcaa acatctccag gatttacgat ttccttccag tggacttctt
     6961 cttgatttat caaaatatgt ttcttgattc tcaaaaaatg acggattttt ctagggatga
     7021 ggagttgttc ctcaagtaat tgctttactg tcatttgagg tagagaggcg ggtaatgtaa
     7081 atgtgaattg catacagata ttgtaacaaa aaaagcccta tttggatagg aaatagctaa
     7141 attcttgtct tcctatgatg aagatgataa aataaacgca tgaaattaga taaattattt
     7201 gagaaatttc tttctctttt taaaaaagaa acaagtgaac tagaggactc tgattctact
     7261 atcttacgtc gctctcgtag tgatcgaaaa aaattagccc aagtaggtcc gattcgaaaa
     7321 ttctggcgtc gttatcatct aacaaagatt atccttatac taggtttgag tgcaggcttg
     7381 ctagttggaa tctatttgtt tgctgtagcc aagtcgacca atgtcaatga tttgcaaaat
     7441 gccttgaaaa ctcggactct tatttttgac cgtgaagaaa aagaggctgg tgccttgtct
     7501 ggtcaaaagg gaacctatgt tgagctgact gacatcagta aaaacttgca gaatgctgtt
     7561 attgcgacag aagaccgttc tttctataaa aatgacggga ttaactatgg ccgttttttc
     7621 ttggctattg tcactgctgg acgttcaggt ggtggctcta ccattaccca acagctggct
     7681 aaaaacgcct atttatcgca ggatcaaact gttgagagaa aagcgaaaga atttttcctt
     7741 gccttagaat taagcaaaaa atatagtaag gagcaaattc taaccatgta ccttaacaac
     7801 gcttattttg gaaatggtgt gtggggtgta gaagatgcga gtaagaaata ctttggagtt
     7861 tctgcatcag aagtgagtct ggatcaagct gcgactctgg cagggatgct caaggggccg
     7921 gaactgtata atcccttgaa ttccgtagaa gattctacta atcggcgcga tactgtcttg
     7981 cagaatatgg ttgcagcagg atatattgat aaaaaccaag aaaccgaagc tgctgaagtt
     8041 gatatgactt cgcaattgca cgataagtat gaaggaaaaa tctcagatta ccgttacccc
     8101 tcttattttg atgcggtggt taatgaagct gtttccaagt ataatctaac agaggaagag
     8161 attgtcaata atggctaccg catttacaca gagctggacc aaaactacca agcaaatatg
     8221 cagattgttt atgaaaacac atcgctattt ccgagggcag aggatggaac gtttgctcaa
     8281 tcaggaagtg tagctctcga accgaaaaca gggggagttc gtggagttgt cggtcaagtt
     8341 gctgacaatg ataaaactgg attccggaat ttcaactatg caacccaatc aaagcgtagt
     8401 cctggttcta caattaagcc tttagttgtt tatacgccag cagttgaagc aggctgggct
     8461 ttgaataagc agttggataa ccataccatg cagtatgaca gctataaggt tgataactat
     8521 gcagggatca aaacgagtcg agaagttcct atgtatcaag ccttggcaga atcgcttaat
     8581 ctacctgctg ttgccactgt taatgatttg ggtgtcgata aggcttttga ggcaggcgaa
     8641 aaattcggac tcaacatgga aaaggtcgac cgtgttcttg gtgtcgcctt gggaagcggt
     8701 gttgaaacca accctcttca aatggctcaa gcatacgctg cctttgcaaa tgaaggttta
     8761 atgcctgaag ctcattttat tagtagaatt gaaaatgcta gtggacaagt tattgcgagt
     8821 cataaaaatt cacaaaaacg ggtgattgat aagtctgtag ctgacaagat gaccagtatg
     8881 atgttgggga ctttcaccaa cggtaccggt attagttcat cgcctgcaga ctatattatg
     8941 gcagggaaaa ctggaacaac tgaagcagtt ttcaatccgg agtacacaag tgaccagtgg
     9001 gtaattggtt atactccgga tgtagtgatt agccactggc ttggctttcc gaccactgat
     9061 gaaaatcact atctagctgg ctctacttca aacggtgcag ctcatgtctt tagaaacatt
     9121 gccaatacca ttttacctta tacgccagga agtaccttta cggttgaaaa tgcttataag
     9181 caaaatggaa ttgcaccagc caatacaaaa agacaagtac aaaccaatga taatagccag
     9241 acagatgata atttgtctga tattcgaggg cgtgcgcaaa gtctagtaga tgaggctagc
     9301 cgggctatct cagatgcgaa gattaaggaa aaggctcaaa caatatggga ttcgatagtc
     9361 aatctatttc gctaagatgc tgtcaatcga aagtgattat gtccccaaaa aatggagagt
     9421 ttgagggcaa ttattttgat ttcatttgac acgagga
//
LOCUS       DAVKUR010000066         9076 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKUR010000066 DAVKUR010000000
VERSION     DAVKUR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9076
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.066"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            405..566
                     /locus_tag="VW749_001867"
     CDS             405..566
                     /locus_tag="VW749_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175855.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            658..2337
                     /locus_tag="VW749_001868"
     CDS             658..2337
                     /locus_tag="VW749_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0175856.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            2605..3171
                     /locus_tag="VW749_001869"
     CDS             2605..3171
                     /locus_tag="VW749_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175857.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            3493..3681
                     /locus_tag="VW749_001870"
     CDS             3493..3681
                     /locus_tag="VW749_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0175858.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3743..4501
                     /locus_tag="VW749_001871"
     CDS             3743..4501
                     /locus_tag="VW749_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0175859.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            4559..5413
                     /locus_tag="VW749_001872"
     CDS             4559..5413
                     /locus_tag="VW749_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0175860.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            5525..6409
                     /locus_tag="VW749_001873"
     CDS             5525..6409
                     /locus_tag="VW749_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0175861.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            6548..6649
                     /locus_tag="VW749_001874"
     CDS             6548..6649
                     /locus_tag="VW749_001874"
                     /inference="COORDINATES: protein motif:HMM:NF014902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0175862.1"
                     /translation="MNTLGDKLMELSAIYHRPESEYAYLYKDKKLHI"
     gene            6713..8311
                     /locus_tag="VW749_001875"
     CDS             6713..8311
                     /locus_tag="VW749_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0175863.1"
                     /translation="MEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTE
                     GQNILYGDKGCVENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFAN
                     GNALLNPEGTLDWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSN
                     HKYNTTDYFEIDRYFGDKETFRELVDQAHHRGMKVMMDAVFNHIGSQSLQWKNVVKNG
                     EQSAYKDWFHIQQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATY
                     WIEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHA
                     VMNYPLSDSIKDYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWT
                     ANEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNF
                     MKRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEA
                     VALASNCQELENQLVISPDGFVIF"
     gene            8586..9041
                     /locus_tag="VW749_001876"
     CDS             8586..9041
                     /locus_tag="VW749_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175864.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         3187 a         1276 c         1922 g         2691 t
ORIGIN      
        1 tttgttacat caagataaat attttctgat ggtcaaattt taaaaagatt aataactctc
       61 gataaatttt gaaccttaac aattgaatag accaagacaa gacgttaatt atttttggag
      121 cgtaataacc tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa agttctgcta
      181 agcaaaaaga aagtgagcga taagtaagag tttgaatata gggagggata ccctatccgc
      241 tatgaagaaa atgaggataa tgatacttct aaggttgaag ccggctcatc cggaatagag
      301 gcggaggtga gattcctatg ttgctaatcc aaagcacttg tcaatgtcaa aaaacttaat
      361 taaacaaata attattagat ataaaacttt agaggaggta tatattggac aatgactgga
      421 atggattggc tgatttaata gcaaatctga ttgcaaaata tgctggtgct ttagatttag
      481 ataatctacc cgatccaacg ccagcaaaaa atcaagagat gaaaaatagt tttgacatgg
      541 caaaaacaca aattgagacg gactaataaa agtgttataa tatacttgaa atgatagtcc
      601 aaacttaaat taaaaaaatt atatatgata tagaaaaatt atattgaggt taatactatg
      661 tcaaaagaaa aaataaaagt atacctctat acacgagtat ctacgtcaat acagatagag
      721 gggtattcgt tagaggcaca aaaatcacga atgaaagctt ttgctattta caacgattat
      781 gaaattgttg gagagtatga agatgccggg aagtctggca agtctattga aggtagaata
      841 cagttcaatc gaatgatgga agatataaaa tctggaaaag atggagtatc ttttgttctt
      901 gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg ttctttctac acttcagata
      961 atgcaggatt atggagttaa tcttatctgc gttgaagatg gcattgattc atctaaagat
     1021 gctgggaaac taatgatttc tgttttatca gctgtggctg aaatagaaag agaaaacatc
     1081 cgtattcaaa caatggaagg ttgcattcaa aaagcaaggg aaggaaaatg gaatggtggc
     1141 tttgctccgt atggatataa acttgaagac ggcaagctgt ttataaatga ggaagaggca
     1201 gttgcaataa gaacgatttt cgaccagtat gtaaatacta cgataggagc caatgggata
     1261 tctaaatact tagagaatca tggaattaga aaaatcccaa gacagaatgg taagaatcct
     1321 ttgtttgatg caggtcttat aagaaagata ttaaagaatc ctgtatataa tgggaaaata
     1381 gcatttggaa gaagaacttt agaaaaagtt catggtacaa gaaatgaata taagcaggtt
     1441 gaacaagatg aatatctaat atctgaaggg atacatgaag ctatagtttc cgatgaagtt
     1501 tggcaagctg ctcaggttaa gctaaaatct caagcaaaga aatatgagca tgtgaataaa
     1561 ggaaaagata cacgcacaca cttgctttct ggaattgtaa aatgcccgat atgtggagtg
     1621 ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg gcacaaagta taaagatttt
     1681 tattactatg gttgtaaaca taggcagatg ataagaggtc ataagtgtac attcagtaag
     1741 caaattagag aagaattgtt agatgatgct gttgcagagg tgattgtcaa gatagtaagt
     1801 aatccgaaat ttgcttctat gatgcaagaa aaaatcaaca tgaaggtgga tacctctgaa
     1861 atagaaaaag aaatagataa ttaccaaaag gaattgagaa agagtcattc tacaaagttt
     1921 aagctaattg aggaaataga taatttagat gttgaagata agcactataa gagaaggaaa
     1981 caggatttag atgatagact atatcgtatg tatgacaaaa tagatgaatt agaatcatca
     2041 ctaattgatg cgaaagcaaa gaaacagact attgaagctg aaaaacttac aggagataac
     2101 atatataagg ttctgatcta ttttgataag ctctataaag tcatgaatga tgtagagcgt
     2161 aggcagttaa tttcagcttt gatttctgaa attcaagttt atgaagaaaa acaatctaac
     2221 ggacaatggc taaaatccat tacttttaag ctaccaatta tagaagaaaa tctcaacata
     2281 gatttggaca atgatgaaca agttgaatgt gtaagtttat tagagaaacg tagttaatcc
     2341 tcaaaaggtt ccccaaactt tttgagtccc actgacgcat cacgctgagg cggtatcact
     2401 gcttgtacga gttgaagcat cagcgaagta aaagtagatg ttcagccaat gcgacgaggt
     2461 gagaccgaag gtcgataagg tgtgttctgg gtataggact cgtaaagtaa gtaggaaata
     2521 tgatgagatg atacagagag cctgaattgg tcaggtgacg tgcttattta cattagcctg
     2581 ataatgaaaa tggagagatt atcgatggtt atattggaat tgtaccaaaa tgattattct
     2641 aaagatttag tagcatttga ttccatagaa gatgggaaag cctttgtggc tcaaatcccg
     2701 ggatacactc tggaaacaga agatggtttt gaagtggagt attttaatcc taaaaacata
     2761 ccggattata tggaaattat ttttaacgga aatattgttc ctttatctaa atttatgttc
     2821 gatcctgagg aaaatgtaaa cattatttgg aaagagattt caaatttatc cctcaaaaat
     2881 gatagagtga tcgaaggata ttcaaaaatt gatgcatatg tcgttaacaa ccatgaagtt
     2941 aaagcctatg tcgaaacaag agaaacgaac tatcgtaaag caaaagactt cttagaaagc
     3001 cgcggatatg aaatcgacag aagctttttc ggaagtgaag acggtgaagc gattctttac
     3061 agaaaaaaag ggatcgaagt ttggcatttc ttgtgtcact tagacccaat gtttgtagag
     3121 attgaagatg tagaaggata tgttaaagaa gaagttggag agattcaata gtcaaccaaa
     3181 gttccttgtg agtatatacc tttgctagta aaagagtcaa aacgttataa cgaagggggg
     3241 gaagaaaacc cttgagtgta agtctttttc ttgtttagag ggaaagtatt agagtagccg
     3301 ctcataattt atactagatt tgataactga tttgagacag attttatttc tataaatatt
     3361 gtgaaaattt tttaatacca aagatttaaa gttactgtgt taaaaatcct ctccactttt
     3421 aaactaatgt attataaaag ccagttgaca caagtgttac acctgtgata gaattaactt
     3481 gaggtgatga aaatggcaac cgataaaaat agaataatga ttagcttgga tgataaaaat
     3541 ctagagaaac ttgaaaattt agtagaagat gctagagata gaaggggaat gcgactaaca
     3601 aagtcccagg ttattgaatt actcctaaat accgttgatt atttcgatga tattatgggg
     3661 gctatttact caaaaaaata agagcaaaat tgctattatt ttttacaaat tggtgtaaca
     3721 ctagtgatat aggagtgatg aaatggttgt ttatattaga caaagtaaat taccaagtga
     3781 ggtttcaatt aataaatacc atgctcaagt aggtgcctac ttacaaggag aagaagctgt
     3841 tttatatcaa tctttttctg aaataaaaga gttaacaagt gaagatatag ttgtagatta
     3901 tataatggag actagagcat tactaaaaat gatgggctta aacgttccgg ttcatgacta
     3961 tcctattgag cttaaagagt tttatggtcg aaagatttat gctggtattt taggagagat
     4021 tgtgaatata cctgataatt ggggaaaatt tattaagcct aaagctggtt caaaagtctt
     4081 tactggaaga gttgttaatg gaacccatga tttaataggt attggtctac ctttcgacta
     4141 tcctatatgg attagtgagg ttgtagaatt catagctgaa tggcgttgtt ttgtgttaga
     4201 tggtcgcgta ttagatgttc gaccctatac aggtgattat catgcacaat ttgatgcaag
     4261 tgtaattgat gaagcgatat catgttggaa agatgcgcca atagcttatg gactagatat
     4321 cggtgttact cgcgatggca gaacacttgt tgttgaagta aatgatggtt atgcattggg
     4381 aaattatggc ctatctcctt taaaatcaat caattttcat agagctaggt ggaaagaaat
     4441 ggtaaaaccc tattttgaaa aaaatgaaat ttttaaaatc caacaggatg ttgttttcta
     4501 aaataaatat ggtatataac caatataaaa agcatcaaaa tgaacaagga ggaatctgat
     4561 gcttggagca attattggag atattgtcgg ttctgtttac gaatggaaca atatcaaaac
     4621 aaaggacttt cctttatttc ggaaggactg cttttttaca gatgacacgg ttatgacctg
     4681 tgctgttgca gaagcaatta tgaatggtgg acaaaaagac gatttcattg acgcgatgaa
     4741 gaaatatggc agaatgtatc cgaatgctga ttacggtgct cggtttaatg catggctaaa
     4801 cagcgataac cgtgagcctt ataatagctt tgggaatgga tcagctatgc gtatttctcc
     4861 atgtgcttgg atcatggact gtggttttta tgcgaaaact ggtatgtggc catcatctag
     4921 aggacttacg agtctttctg cagaggtaac tcataatcat ccagaaggtg tcaaaggcgc
     4981 tatggctaca gctgatgcta tctttctatg tcgtttttac tttggtggtt attgtagaga
     5041 gtacgagcaa tcaattaacg acaatcctac agagtgtaaa agacgaatta aggattatat
     5101 agaaaaagaa tacgattaca atctatctca aactttagat gaaatccgtc ctaactatcg
     5161 ttttaacgaa acatgtcagg aaactgtccc tcaagccatt atcgcctttc ttgaaagtag
     5221 agacttcgaa gatgcgataa gaaatgccat ctcacttggt ggcgacagtg atactctcgc
     5281 agcaatcact tgtagcatag cagaggcagc ttacggtatt cctgattgga tcaaggataa
     5341 ggcctattct tacttggatg aacccttaaa ggatgtagtt aggcgatggg aaaatagaat
     5401 aaaagcgtat taatctccag tacgtcagat ttctcttttc tgtattttca ttgtataata
     5461 ggattacatt tacttgcata cgacgaaatg taaacatttc tgtttaaaat taaggataaa
     5521 atcaatgaaa aaagcaatgg taattatcaa ccctacttct ggtggcgaga aggctttgga
     5581 ttacaaagaa aagctggaga ataaagcaaa agaatacttt gaatatgttg aaaccaaaat
     5641 taccgaaaaa gcgctggatg caacacattt tgctgaagaa gcttctcgtg agcagtatga
     5701 tgcagtggtt gtgtttggtg gagatggaac tgtcaatgaa gtcatttcag gtattgatga
     5761 gagagactac attcctaagt tagggattat cccaggcggt acgggtaacc tcattacaaa
     5821 acttttggaa atcaatcaag acatcgatgg cgcaattgac gaactggatt ttgatttaac
     5881 caataagatt gatatcggta aagcaaatga caactatttt ggttatatct ttagtatcgg
     5941 ttctctgcct gaggcgattc acaatgttga aatagaggac aaaacaaaat tcggtatttt
     6001 aacctatgct gtaaatacca tgaagtctgt catgacagat caggtcttta acattaaggt
     6061 tgagacagaa aatggaaatt atgttggtga agctagccat gttttggtcc ttttgacaaa
     6121 ttacttcgct gataagaaaa tctttgaaga aaacaaggac ggctatgcca acattttgat
     6181 tctgaaagat gcctctatat tctccaaatt atccgtcatt cctgatttat taaaagggga
     6241 tgttgtcgca aatgataata tcgagtatat caaagcgcgt aatattaaaa tctcttcaga
     6301 tagtgaattg gagtcagatg ttgacggaga taaatcagat aacctacctg tagaaatcaa
     6361 agtcctagct cagcgagtag aagtattttc aaaaccgaaa gaggattagt atatagagaa
     6421 agcctttttt aaggcttttt gtatacttta aaagatagtt cctttaacaa cggacattcc
     6481 ttgcaaatag tttacaaaaa tagtatactg gatttattga gtttgaaaac gtttgcgtaa
     6541 aatttgaatg aatactttag gagacaaatt gatggaattg agtgctattt accataggcc
     6601 tgagtcggag tatgcctatc tttataagga taagaaactc catatttgaa ttcgaactaa
     6661 gaaaggggac attgaaagca tcaacttgca ctatggggac ccttttatct ttatggagga
     6721 gttttatcag gatacaaaag aaatggtcaa gataacttct ggtaccttat ttgaccattg
     6781 gcaggttgaa gtgtcagttg actttgcacg tatccagtat ctctttgagc tcagagatac
     6841 agaaggtcaa aatattttgt atggcgataa agggtgtgtg gaaaattctc tagaaaatct
     6901 tcatgcaatt gggaatggat ttaagttgcc ttatcttcat gagattgatg cctgcaaggt
     6961 tcctgactgg gtttcaaata cggtatggta tcagatattt cctgaaagat ttgccaatgg
     7021 caatgctcta ttaaacccag aagggacttt agactgggat tcatctgtca cacctaagag
     7081 cgatgatttc tttggtggtg atttacaggg gattattgat catatggatt acttgcaaga
     7141 cttgggtatt actggactat atctttgtcc catctttgaa tctacaagca atcacaagta
     7201 caatacgaca gattactttg aaattgaccg ttattttgga gacaaggaga cctttcggga
     7261 actggtggat caagcgcatc atcgtggcat gaaagtcatg atggatgcgg tatttaatca
     7321 tattggttcg caatctcttc aatggaaaaa tgtcgtcaaa aatggcgaac agtctgctta
     7381 taaggattgg ttccatattc aacaattccc agtgacaact gaaaagctag ttaataagag
     7441 agacttaccc tatcatgttt ttggtttcga ggactatatg cctaagctaa atacagccaa
     7501 tccagaggtc aagaattatc ttttaaaggt tgcgacttat tggattgaag agtttaatat
     7561 cgatgcttgg cgtttggatg tggctaatga gattgaccat cagttctgga aggattttcg
     7621 taaggcagtt ttagctaaaa atcctgatct ttatatccta ggagaagtct ggcatacatc
     7681 tcagccttgg ctaaatggag atgagttcca tgccgtcatg aattatcctt tatctgatag
     7741 tatcaaggac tatttcttac gaggaattaa gaagacagac cagttcatcg atgaaatcaa
     7801 tggagagtct atgtattaca agcagcagat ttcagaggtc atgtttaatc tcttggattc
     7861 acatgataca gagcgaatcc tgtggacggc caatgaagat gttcaactgg ttaaatcagc
     7921 cttagccttt ctctttttac aaaaaggaac accgtgcatt tattacggaa ccgagctagc
     7981 cttgactgga ggaccagatc cagattgtcg tcgttgtatg ccttgggaac gtgtatcaag
     8041 tgacaatgat atgctgaact ttatgaagag gctgattaag attcggaaat acgcgtcagt
     8101 aatcatttcg catggcaagt atagccttca agaaatcaaa tctgatctag tagctctgga
     8161 atggaaatac gaaggacgga tcctcaaagc aatattcaac caatcaacag aagattatct
     8221 tttagagaaa gaagcagtag cactagcaag caattgccaa gaattggaga atcagcttgt
     8281 catctctcca gatggatttg tgattttcta aaaactagtt gatgaagatt atggtacatt
     8341 tcatatctta tatagtataa taaggctagt tactaaactt gtaaaggaga acttaaatga
     8401 attgtagagg acatgaaaca agacaaagaa ttgttagaga ttttgaagtt tagcctaaag
     8461 cacatattaa gctgttagca aatcaacaaa aacatagtga tgcaggagca actattgaag
     8521 atgaatatta tgtatttatc gctgagagta aaattgatgg caagaaggaa gttattcagt
     8581 gttgcatggg tgcggcaagg gattttttag aactaattaa tcacaaaggg ctacctcttt
     8641 ttaatccgct tgtaggtgat tctcatgtaa ataatagaca agaatatgac aatacaggga
     8701 gtggaaattt acaacctgaa aagtggaatg aaactgcaaa gcagctttat aatgctataa
     8761 tgtggttgat tattttatgg aatgctaagc cggatacacc tttatttaat tttaaagacg
     8821 aagtaattaa gtataaaaca tatgagcctt ttgaaagcag tataaaaaga gtaaatacta
     8881 ctataaagaa tggtagtaaa gggaaaactc tgactgagat gattaatggc tacagagcgg
     8941 ataacgatat tagagatgaa atttgtaact ttaatattct gaaaaataaa attcgtgata
     9001 tgaaagacca acaaggaaat acaatggaat cttactttta gttattgttg aattttgggt
     9061 attctataaa atatcc
//
LOCUS       DAVKUR010000067         8939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKUR010000067 DAVKUR010000000
VERSION     DAVKUR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.067"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(299..1147)
                     /gene="dprA"
                     /locus_tag="VW749_001877"
     CDS             complement(299..1147)
                     /gene="dprA"
                     /locus_tag="VW749_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0175865.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            complement(1243..1932)
                     /locus_tag="VW749_001878"
     CDS             complement(1243..1932)
                     /locus_tag="VW749_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0175866.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1944..2822)
                     /locus_tag="VW749_001879"
     CDS             complement(1944..2822)
                     /locus_tag="VW749_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0175867.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2812..3681)
                     /gene="licA"
                     /locus_tag="VW749_001880"
     CDS             complement(2812..3681)
                     /gene="licA"
                     /locus_tag="VW749_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0175868.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3698..4720)
                     /locus_tag="VW749_001881"
     CDS             complement(3698..4720)
                     /locus_tag="VW749_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0175869.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4725..5432)
                     /locus_tag="VW749_001882"
     CDS             complement(4725..5432)
                     /locus_tag="VW749_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0175870.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5768..7255
                     /gene="tacF"
                     /locus_tag="VW749_001883"
     CDS             5768..7255
                     /gene="tacF"
                     /locus_tag="VW749_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0175871.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7265..8068
                     /locus_tag="VW749_001884"
     CDS             7265..8068
                     /locus_tag="VW749_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0175872.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8070..8879
                     /locus_tag="VW749_001885"
     CDS             8070..8879
                     /locus_tag="VW749_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0175873.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2802 a         1803 c         1517 g         2817 t
ORIGIN      
        1 caaagcgcaa actaggaagc tagccacagg ttgctcaaag cactgctttg aggttgtaga
       61 taagactgac gaactcagct caaaatactg ttttgaggtt gcagatggaa gctgacgtag
      121 tttgaagaga ttttcgaaga gtattatatg agaaaaatcc tctactctac taatccactt
      181 agaaaaaacg catattagca agtgttaaaa acttgctaat atgcgtttta ttatggaaat
      241 gttgggttca ttttctctta aaattgattt tttcttagaa ttctagctta ggtcattttt
      301 aaaattcaaa ttccgcaaga acatcttgcc cactggtgag caattttgct ccttcttgaa
      361 tcaaatgatg gcaaccgtct gatagtccat ctaaaatgct accaggaata gcaaagacat
      421 cgcgtccttc ttccattgct cgctcacacg taatgagact acctgaacgc atcttagcct
      481 ctgctacaat cacaccacga caaagtccag caatgatgcg attacgggca ggaaaatgaa
      541 atttcagagg ttgttcgcca ggtccatatt cacttagaac cagatggtca ttgccgatgt
      601 agtcttgcaa gcgtttattg gctttaggat aaaacacatc cagtcctgtt ccaatcactg
      661 caatggtttt tccgccattc tgaagagctg ccatatgagc tgctgtgtca atgcccttgg
      721 ccagaccact gacaataacc agttcatttt ccaagccttg aatgactttt tcaactgact
      781 tagctccctg tttgctacaa gcacgactgc ccacgaccgc taccttcggg aatttcagga
      841 ggtcaagatt tcccttgtaa aataaaagta caggcgcatc atatatttca ctcaaatccc
      901 aaggataaca gtcatctaaa atagagaaag atggaaattt ttgaaactct ttcgacaaat
      961 gcgcatcgtc tatctgaaaa taacgttcca taaaaacggc tggattacgg caacctgata
     1021 tatctgcaat atcacccaac aaaagctcct gatcaacatt ttcaccgtat tctagcactt
     1081 tcaaaatctg ttgattggtc aaacctgatt tttttaactt atagatttca tagtttgtga
     1141 ttttcataaa taactccatt tctttttcta ctcatctatc tattcgtaaa agttcgtaaa
     1201 aaatcaaaaa acatccgact attttgtcag atgttggaat ctttaatttt cgtttttaag
     1261 aatttcttct aatttacgat agtcttggac actatcgatc tcataaatgc tattgccttc
     1321 taattcttca acatagacat ctagctcttt gatattatcc ttaaccatat tgtcccaata
     1381 gagatcaaca aattcaccac ttgcataagc cttgtcgata aagctgacaa tcttttctgc
     1441 agttggagca tcccagaagg atacaccact aaggatgcga cctgccttgc tatcaacaat
     1501 aatgtcttga accttgtagt catctccata gaccaagaac cattcgttgg tacaatcttc
     1561 acgataaaca ctaaaataag tcgaacgtgt caaatcattg cggaacatat ttttaaagag
     1621 ataattgtca gcatcaataa catagctgtt ggccaattct tcttttacaa gatagagaga
     1681 gtaaaagtta ttgtagtcag cgtatttatc attgaaaacg aggcgaacac cgtatttttc
     1741 ttttaagtaa tcgaattgtt ctttaagata accaacaatg atgatgatgt cattgattcc
     1801 tttttctttg agaaactcaa tttggtattc aatcaaaggt ttttgattaa cctgaaccaa
     1861 ggctttaggg gtattttcag tcataggacg caagcgagtt cccaatcccg ctgctaagat
     1921 aatggctttc acacgaatct cctttattct ttaataataa tataaactcc agcaatgacg
     1981 acaagtgacg tcataatggt cagcatatct agcggtgcac ccaaaaaaac aactgcaaac
     2041 aagaccgtcc atactacata gctcacgttc aagcctgtag ccttggctgg ttgcaagcga
     2101 ttgatagcga tataataagc caagtaggaa atcatatcaa aggctgcaaa aacaatcatg
     2161 agacctagca attgtccatt ggctactgca gtaaatgact gatgagagaa gagcacaatc
     2221 acaagatagg acaagaacga agtcacttga cggattaaga gggcttcgat ttcactcagt
     2281 tcactttcca tagcaaagga gctaagaaca ctctcacttc cccatgcaat agcacaaacc
     2341 aaagcacaga gaatcccaat gtagaaggaa ttaacctgtt caaccttata ggtctgggca
     2401 ataatccctc caataatcaa gacaatccca aatacagtat ttttcgaaat cttgtgcttc
     2461 aaaaagaaga aagccaatag aactgaaatc gcagggtaaa tagccgatac agatgaagct
     2521 aaagaacttc cgatatactt aactgcataa agattggcct gcataccgat agggcctgct
     2581 agcaaggctc cgatgataac actgacattg cgaatattta agaaaattga gaggcgaact
     2641 ttcccttctt ttaccaagag aaaagctagt aagataaaga tgctcaaaaa atcatgagct
     2701 gcagccacca caaagggtga caaatctgta aaaatcgaaa agatataagc actaaccgtt
     2761 agacccaagc cccagaaaat acctgagaga aggccaaaag gaactccgtt tttacttttc
     2821 atctgaacct ccataagaag ccaaaccttt aacagctctt tggtaacgat tcacaccata
     2881 gtcaccaaaa tcttcacctt gctcttcctt atagacagtc catagactcc aaatagtatc
     2941 ttgtaaaatt ttataaatag caatcttttc atgagaaacc ggtgtttggt cactctcata
     3001 gtgagataag aaagtttctt cctcttggga agtgaattca gactctaaaa agagggcagc
     3061 caaatcccac attggatcat tcattgatga atattcccag tcaatcaaat aaagtcgtcc
     3121 ttgaggtgat tcgataaagt tttcaggcac caaatcgata tgacaagatt ttctgtcaac
     3181 acctaagtca gccagtcttt tctctaagga gaagactgca tttctaacag attcatagtt
     3241 ggcataagga atttgttctt caatcaagga ttcgtatttt ttgatttctt caaaaggagc
     3301 aaattctcct cttaattcct tagcagacgt atgaatagtt tgtaatattg gagcaatttt
     3361 gtcgaacttg gtcttgattg acgttgaatc aagcgtaatc gcagattcga tatactcatt
     3421 tactttgata ccagcttcaa tatcaaaaag ataatttttt acatctaagc ctaaatcctt
     3481 tagtagttca agattgtact tttcatcttg tcgattgata agcttttctg tccctttacc
     3541 aaagaattta acaatgtatt gcttatttgt tgttttggcc aaatagtttt gattggtcat
     3601 tccacccagt tgttcaacac tgaggacttc ctcttcttga ctaagtaagg aagaaatttt
     3661 ttctttaatg attttctcca caattaacct ccagtactta tacttcccac ttaaacactg
     3721 ttttaaaggc tgtgtttaaa tcggttgcaa agacacgatg aatatcttta atttctctta
     3781 caggttcttc tagataaagg atatttttaa gacgattggc aaatttcttg acttccatca
     3841 tttggatagc atttttaaaa tcaatgcgac cagaacgaga tgacccaacc aaaatcaagc
     3901 ccttttctaa ggcatcgcga gtattgagat tgactttata ttcgctaact cccatcatga
     3961 gaatcgttcc ctgaggacga atgtagcgaa tcaagtcatt aatagctggt ccagtaccat
     4021 caccaccaca acattcaaaa gcatggtcaa aggccaactc ttcaggaata ttatccgtaa
     4081 tatagcattc tttggcaaat gagaagagtt ccaacttttc ccaatgacga ccaataacca
     4141 caatctctga ttctggcaaa gtatagttga taatattggc aaccacaaaa gctaaacttc
     4201 catctccaat aacggcgatc cgctcccgct tgctatgagc aagagtcaat agacgattca
     4261 tagcgtgcat gcccacactg acaaactctg taatggctgc aaccgtatct tcaatagcat
     4321 cataagccac cacacgatct ttagggagag aaacaaactc tctcataaag ccatcaaatc
     4381 cactagacaa gaaatgggtc cctgtcatgt agttttcata gaattcttca tcactctgca
     4441 taggagactg attgggaatc atgacaactt tttgaccaac ctcgtaggtt ccggtcgggt
     4501 cagaaatgac ggttccacat gactcgtgaa tcattgccat tggaagcttt ttattcaaaa
     4561 tcttgggatc acgttttccc tgatagtaac gctgatccgc atgacagaca gccatgtagt
     4621 tgggacggat aaggatatga ttctcttggt caatagcctc ttcctgatat ttgacattga
     4681 taaacttagg cttagttagt tgataaattt gattaatcat tttactagtc tttctcaatc
     4741 atactttttg caatcttcaa atctgttacg gttgtaatct tcagatttga gtattcacct
     4801 ttggccaagg ccacatcttt tcctttgatc acaaagattt tacatgcatc tgtcaagatt
     4861 tccttctctt catcagaaag agatccataa aggtccatga agtccttgca acggaatgtt
     4921 tgaggtgttt gtccttgata aaggtgagca cgatttggaa tatctgtaat aaattgacca
     4981 ttggtacttt caacgatagt atcaaccgct tctaccactg tgtccactgc gtcatgattt
     5041 tgggcaagtt ggatattgtc ctgaatcatg cgaagtgtaa taaatggacg aacagaatcg
     5101 tgggtaacaa cgatatcctc tggagtaagc ggacgataag catcaatggc ttcaatgatt
     5161 ttcttaatac ttgtattgcg gtcagcacca ccctttgtaa tgatgatacg ttccttataa
     5221 agaggaagat atttatctac aagatcttct gcatgagaaa cccagtctcc atgaacacca
     5281 actacaattt tttcaatact tggctccaag acaaattttt caattgtatg aatcaaaata
     5341 ggtcgattac ctagctctaa aaattgtttt ggcaagttac tgatccccat gcgtgtgcca
     5401 gttccaccgg caagaattcc tgcataaatc atctattttc tcctttgtct tactaaaaaa
     5461 acttattctc tctattatac cacaatctag tcctatcata aaagaaatac tggtcctccc
     5521 cttctagaat aggagaatta tgcagttcta ttattcaaag aaactagtcc atttctagta
     5581 atgactagga attctgtagc aattactaat aaatggctgc gaaattttag agtccttcag
     5641 aataatatac tttccttaaa gaaaacttaa aacttaagat ttgaaacttc aaagtgatta
     5701 cttgacttac tgcccttcat ttcttattag ctaactttat gatataatga aaaacgaggt
     5761 aaattgaatg aaaagtataa aattaaatgc tctatcttac atgggaattc gtgtcttgaa
     5821 tattattttt cccatcctaa ctggaaccta tgtcgcgcgt gtcttggacc gaactgacta
     5881 tggttacttc aactcagtcg acactatttt gtcatttttc ttgccctttg caacttatgg
     5941 tgtctataac tacggtttaa gggctatcag taatgtcaag gataacaaaa aagatcttaa
     6001 cagaaccttt tctagtcttt tttatttgtg catcgcttgt acgattttga ccactgctgt
     6061 ctatatccta gcctatcctc tcttctttat tgataatcca atcgtcaaaa aggtctacct
     6121 tgttatgggg attcaactca ttgcccagat tttttcaatc gaatgggtca atgaagctct
     6181 ggaaaattac agttttctct tttacaaaac tgccttcatc cgtatcctga tgctggtctc
     6241 tattttctta tttgttaaaa atgaacacga tattgttgtc tatacacttg tgatgagttt
     6301 atcgacgctg attaactacc tgattagtta tttttggatt aaaagagaca tcaaacttgt
     6361 taagattcac ctaagtgatt ttaaaccact ctttctccct ctgacagcca tgttagtctt
     6421 tgccaatgcc aatatgctct tcactttttt agatcgcctc ttcctcgtta aaacagggat
     6481 tgatgtcaac gttagttact ataccatagc tcagcgaatt gtgaccgtta tagctggggt
     6541 tgtaacaggt gcaattggag tgagtgtgcc tcgtctcagt tactatctgg ggaaaggaga
     6601 caaagaagcc tatgtttctc tggttaatag aggtagtcga atctttaact tctttatcat
     6661 tccactgagt tttggactca tggttttagg accaaatgcc atcctacttt acggtagtga
     6721 aaaatatatc ggaggcggca tcttgacctc tctcttcgct tttcgtacga ttatcctggc
     6781 cttagatacc attcttggtt cccaaattct ctttaccaat ggctatgaaa aacgtatcac
     6841 agtctataca gtctttgctg ggctactcaa tttgggcttg aatagtctcc tctttttcaa
     6901 ccatatcgtg gttcctgaat actacttact gacaactatg ttatcagaga cttctctact
     6961 tgttttctat attattttca tccatagaaa acaactcatc cacttgggac atatctttag
     7021 ctatactgtt cgatactctc tcttttcact ttcctttgta gcaatttatt tcctgattaa
     7081 tttcgtgtat cctgtggata tggtcattaa tttgccattt ttaattaata ctggtttgat
     7141 tgtcttgcta tcagctatct cttatattag tctacttgtc ttcacaaaag atagcatttt
     7201 ctatgaattt ttaaaccatg tcctagcctt aaaaaataaa ttcaaaaaat cataggagtt
     7261 taaaatgaaa caactaacca ttgaagatgc caaacaaatt gaattagaaa ttttggatta
     7321 tattgatact ctctgtaaaa agcacaatat caactatatt attaactacg gtactctgat
     7381 tggggcggtt cgacatgagg gctttatccc ttgggacgac gatattgatt tatccatgcc
     7441 tagagaagac taccaacgat ttattaacat ttttcaaaag gaaaaaagca agtataagct
     7501 cctatcctta gaaactgata agaactactt taacaacttt atcaagataa ccgacagtac
     7561 gactaaaatt attgatactc gaaatacaaa aacctatgag tctggtatct ttatcgatat
     7621 tttccctata gatcgctttg atgatcctaa ggtcattgat acttgttata aactggaaag
     7681 cttcaaactg ctgtctttca gtaaacataa aaatattgtc tataaggata gccttttaaa
     7741 agattggata cgaacagcct tttggttgct ccttcgaccg gtttctcctc gttattttgc
     7801 aaataaaatc gagaaagaaa ttcaaaaata tagtcgtgaa aatgggcagt atatggcttt
     7861 tattccttca aaatttaagg aaaaggaagt cttcccaagt ggtacctttg ataaaacaat
     7921 cgatttaccc tttgagaatt taagccttcc tgcacctgaa aaatttgata ctattttgac
     7981 acaattttat ggagattata tgaccctacc accagaagaa aaacgcttct acagtcatga
     8041 atttcacgct tataaattgg aggattagga tgcaatattt agaaaaaaaa gaaattaaag
     8101 aaattcaact agccctgctg gactatattg atgagacttg taagaaacat gatattcctt
     8161 attttctcag ttatggaacc atgcttggag ccatccgcca caaaggtatg attccttggg
     8221 atgatgatat tgatatttcc ctttatcgtg aggattatga gcgtttactg aagattattg
     8281 aagaagaaaa tcaccctcgc tacaaggttc tttcctacga tacatcttct tggtacttcc
     8341 ataatttcgc atcgattttg gacacttcta ctgttataga agaccatgtt aagtacaagc
     8401 gtcatgatac cagccttttc atcgatgtct tcccaattga tcgatttaca gacttgagca
     8461 ttgtcgacaa gagctataag tatgtggccc ttcgtcaact agcttatatc aaaaaatcac
     8521 gagcagttca cggtgatagc aaactaaaag attttcttag attatgtagc tggtacgctc
     8581 tccgatttgt caatcctcgc tacttttaca agaaaattga tcaactagtc aaaaatgctg
     8641 taaccaacac tcctcaatat gaaggaggag ttgggatcgg taaggaaggg atgaaagaaa
     8701 tcttcccagt tgataccttt aaagaactga ttttaactga gtttgagggc cgtatgttgc
     8761 ctgttcccaa aaaatatgac caatttttaa cccagatgta tggcgattat atgacaccac
     8821 catcaaaaga aatgcaagag tggtatagtc atagcattaa agcttatcgc aaaaactgat
     8881 tgagggggat tatacaaact actaagatag aggttattca aaaacataat tttagtaga
//
LOCUS       DAVKUR010000068         8077 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKUR010000068 DAVKUR010000000
VERSION     DAVKUR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.068"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            41..1468
                     /gene="galT"
                     /locus_tag="VW749_001886"
     CDS             41..1468
                     /gene="galT"
                     /locus_tag="VW749_001886"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0175874.1"
                     /translation="MYNEIDKIYVKNRVLALIGEEGIDRISDENDLKQIKDYLVEIAL
                     KNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISPQEAVEEFYKLSKDSDY
                     IKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKLVKATNYPKCLLCMENE
                     GYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIFLNSQHVPMAITSKTFE
                     QLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPMEKAKFESEFCFKDFED
                     VNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEVDIIAMTEDVPHHTVTP
                     IARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKENIGLIEVMGLAILPPRL
                     KPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVNSVVQHEAGQVFARVLE
                     DAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1481..2491
                     /gene="galE"
                     /locus_tag="VW749_001887"
     CDS             1481..2491
                     /gene="galE"
                     /locus_tag="VW749_001887"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0175875.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNIFE
                     SVNKIPIPYKIVPRRSGDVATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2655..3314
                     /locus_tag="VW749_001888"
     CDS             2655..3314
                     /locus_tag="VW749_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0175876.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3339..4406
                     /locus_tag="VW749_001889"
     CDS             3339..4406
                     /locus_tag="VW749_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0175877.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4510..5520
                     /locus_tag="VW749_001890"
     CDS             4510..5520
                     /locus_tag="VW749_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175878.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5532..7223
                     /locus_tag="VW749_001891"
     CDS             5532..7223
                     /locus_tag="VW749_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0175879.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7226..7936
                     /locus_tag="VW749_001892"
     CDS             7226..7936
                     /locus_tag="VW749_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0175880.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2718 a         1124 c         1596 g         2639 t
ORIGIN      
        1 aattattgat aattttgttg atagagtaat tgaatacgga atgtataatg aaattgacaa
       61 aatatatgtg aaaaatagag tactagcgtt aataggtgag gagggaattg atcgcatttc
      121 cgatgaaaat gacctgaaac aaataaaaga ttacttagtg gaaatcgcct taaaaaacgg
      181 taaaattaaa gatttaatcg aggaaaagga atgtttagga gcagagttaa tgaatttcat
      241 agttccttta cctagtcgat taaatgatat tttttggagt tcatatgata tatcacctca
      301 agaagcagtt gaagagtttt ataagttaag taaagatagt gattatatta aaacttctgc
      361 tattgctaag aatattgagt ttcgagcatc aactaaatac ggagagctag agattacgat
      421 aaatttgtca aaacccgaaa aagatccaaa aacaattgct gctgaaaaat tagtaaaagc
      481 aactaattat cccaaatgtt tactatgtat ggaaaatgaa ggatatcagg ggcgaataaa
      541 ttatccagca cgttcgaatc atagaattat tcggttgaaa cttggtgacg aagtatgggg
      601 attccagtat tctccctact catactttaa tgagcatgcg atatttttga atagtcaaca
      661 tgtaccaatg gctattacct ctaaaacatt tgaacaatta ttggagattg ttgatatttt
      721 gccaggatat tttgctggtt caaattctga tcttcctatc tcaggaggct ccattcttag
      781 tcataaccac taccagggag ggaaacatat tttcccaatg gaaaaagcaa aatttgagag
      841 tgaattttgt tttaaagact ttgaggatgt taatgctggt attgtaaaat ggccaatgtc
      901 agtaattagg ttacaaagtg aaaataaaaa tcgcttgtta gatttagcta ctaaaattct
      961 aaataagtgg agagaatatt cagatttaga agtagacatc attgctatga ctgaagatgt
     1021 cccacaccat acggtgactc ctattgctcg taaagtggac gggagatacg aattagatat
     1081 tgttctaaga gataatcata ctactgaaca atacccagat ggtgttttcc atcctcatca
     1141 agatgtacaa catattaaaa aggaaaatat cgggttaatc gaagtgatgg gacttgcgat
     1201 attaccacct cgtttgaaac cagagttaga agaagttgga aaatatcttt taggagagga
     1261 taatgcaatt gcggattatc atttagaatg ggccgaccaa ttgaaagaaa aatatcctcg
     1321 cattaataaa gaagaggtta atagcgtagt tcaacacgaa gcaggacaag tgtttgcgag
     1381 agttctggaa gatgcaggag tttataagaa tacaccgtct gggcatgaag cgtttatgag
     1441 atttgttaag tcggttggaa ttaattagga ggaaacccag atggcaatat tggtaacagg
     1501 cggagctggt tatattggta gccataccgt agtagaatta ctaaatttag gaaaggaagt
     1561 tatcattgtc gacaaccttt cgaactctag caaattggtg ctagaccgta ttgaagcaat
     1621 tacaggaata cgtcccgtgt tttacgaatt agatgtttgt gataaacaag cattgagaaa
     1681 ggtatttgaa caagaatcga ttgatgctgc aattcatttt gcaggttata aagctgtcgg
     1741 agaatccgtg caaaagcctg tgatgtacta caaaaataat attatgagta cattggcact
     1801 tgttgaagtg atgtcagaat ttaatgttaa aaagattgtc ttttcttcaa gtgcgactgt
     1861 atatggaatt aacaatcagt cacctctaat tgagacgatg caaacaagtg cgacaaatcc
     1921 ttatgggtat acgaaagtga tgcttgagca aattttaaaa gatgttcatg tggcagattc
     1981 agaatggagt attgcgttgc ttcgttattt caatccaatt ggtgctcatg agtctggttt
     2041 gattggggaa gatccctcag gaattcctaa caacttgatg ccttatattg cacaagtagc
     2101 ggtaggtaag ctatcagagc taagtgtgtt cggaaatgat tatgatacgc ttgatggtac
     2161 tggtgtgcgt gattatatcc atgtagtaga tttagcaata ggacatataa aagctttaga
     2221 aaaagtatct gaaaaaacag atgtttatat ctataaccta ggctcgggag aaggcactag
     2281 tgtattacaa cttgtaaata tatttgaaag tgttaataag atccctattc cttataaaat
     2341 agttccaaga cgttcaggag acgttgcaac ttattatgca aatgcagaca aagcatataa
     2401 ggaattaaat tggaggacaa caaaatcgat tgaagacatg tgtagagata catggaattg
     2461 gcaatcaaaa aatcccaatg gctataattg atgatactgt ctatatgagt gctgtatttt
     2521 ggaaaaatta cttaaccttt taatgaaaga taaattaaaa aaaatgtttg acagcgcttg
     2581 acaaaggaaa cggtttcatt gtataatgta aacacaatga caccgatgtc aaatataaaa
     2641 aagaaggtct ttatatgaaa aacttaacaa aaattaagtt caaagaaaat ggggaattta
     2701 atcatttccc tgggaataca gttgtagcaa atctttatac taaacaagat ttgatggaag
     2761 ttgttgatat tattcaatca cgttatagag aattaccatt tatcgataag tttactttaa
     2821 ctccaaggaa ttctattcac atgactgtaa ttgaattgtt gtgccatgaa aatcgtgaaa
     2881 cggagttttg gagcagtaat cttcctctag atacaccttt acaggaaata catgattact
     2941 ttgctaaaca acttgaaatt tttccattgt tggatgaaga aattcatatg cgtataactg
     3001 aaatgggaaa acaaaacata ctagttgaac ctgcagatga agcttctgca aagagattag
     3061 aagaaattcg tacttatgtc tcagaaaaag caggtgtttg tttccctaat catgatagat
     3121 atcaattcca tatttcaatt gggtatcttc ggattcctct aaccgaagag gaggaagaag
     3181 agtttactaa agtcagagca gaattaactg aaattttatt agagaagatt ccaactatta
     3241 ctgtaaaccg tattgactat actgtatttg aagatatgag acaatttgtt ccatatcacg
     3301 aaaaatttaa ataaaataat aaaaaaggag aacttatcat gaaaaaaatg aaagtttggt
     3361 ctactgtact tgcaacggga gttgctctta ctacacttgc tgcttgctct ggaggttcaa
     3421 attctacgac tgcttcttca tctgaagaaa aagctgataa aagtcaagaa ttagttatct
     3481 attcgaactc agtctcaaat ggtcgtggtg attggttaac tgctaaagca aaagaagctg
     3541 gttttaatat aaaaatggtt gatatcgctg gcgctcaatt agcagaccgt gttattgctg
     3601 agaagaataa tgcagttgca gatatggtat ttggaattgg tgctgttgac tcaaataaaa
     3661 ttagagatca aaaattacta gtacagtaca agcctaaatg gttagataaa attgatcaat
     3721 ctttatcaga taaagataat tattataatc ctgtgattgt tcaaccatta gttttaattg
     3781 gggcgcctga tgtaaaagaa atgcctaaag attggactga attaggtagt aagtataaag
     3841 gtaaatattc aatttatggt cttcaaggtg gtacaggacg ggcaattcta gcaagtatct
     3901 tagttcgtta cctggatgaa aaaggagatt taggcgtatc agaaaaagga tgggaagttg
     3961 caaaagaata ctttgcaaat gcctatactc ttcaaaaagg tgaaagctca gttgttaaag
     4021 cgttagataa agaaagccca attcaatacg gtatgatctg gggttctgga gcgttaatcg
     4081 gacaaaaaga acaaaatgtt gaattcaaag ttatgactcc tgagattggt gtaccatttg
     4141 taactgaaca aactatggtt ttaagcacta gtaaaaaaca agcgttagct aaagaattta
     4201 ttgattggtt tggtcaatca gaaattcaag tagaatatag taaaaaattt ggatctattc
     4261 ctgcaaataa agatgcccta aaagagttac ctgaagatac gaaaaaattt gttgatcaag
     4321 tgaaaccaca aaatattgac tgggaagctg ttggaaagca tttggatgaa tgggtagaaa
     4381 aagctgaatt agaatacgta aaataagaaa taagagttat tttttatgtc caagtctctc
     4441 tattatttct aaatttaagg aagaaataaa gagaggcttt tggttttagt aatagaggga
     4501 gttagtgaga tgattaaatt tgataatatt caaattaaat atggtgattt tgttgcaatt
     4561 gataatctga atttagatat acatgaaggg gaattcttta catttcttgg gccttcagga
     4621 tgtggtaaat caactacttt gagagcattg gtaggttttt tagatccatc atcaggaagt
     4681 attgaagtta atggaacaga tgtcactcat ttggaacctg aaaagcgtgg gattggtatt
     4741 gtatttcaat cttatgcgct atttccaact atgactgttt ttgataatat tgcatttggt
     4801 ttaaaagtta agaaggtagc tccagatgtt attaaagcta aagtatcagc agtggcagca
     4861 aaaattaaga tctctgatca acagttacag cgtaatgtat cagaattatc tgggggtcaa
     4921 caacaaaggg tagcattggc tcgtgctctg gttcttgaac ctaaaattct ttgtctagat
     4981 gaaccattgt caaaccttga cgcaaaatta cgtgtagatt tgagaaaaga gttgaaaaga
     5041 cttcaaaaag agttaggtat tactacttta tatgttactc atgatcaaga ggaagccttg
     5101 actttatctg atagaattgc agtctttaac aatggataca tcgaacaggt cggtacacca
     5161 gtagagattt atcataattc tcaaactgaa tttgtatgtg attttattgg agatattaat
     5221 gttttgaccg atgaaacagt ccacgaagta ttattgaaaa atacaagcgt tttcttagag
     5281 gataaaaaag gatacattcg attagagaaa gttcgattca atcgtgaaac tgaacaagat
     5341 tttattctaa aagggacaat tattgatgtt gagttttctg gagttacaat tcactataca
     5401 ataaaagttt ctgaaagtca gattcttaat gtaacaagta ttgatagtca ggctgctatt
     5461 agatctgtcg gagaaagtgt ggaattattt atcacaccat cagacgttct gcaattttaa
     5521 ggaggtgcag tatgcgtcat aaattaaatt taaaagattg gcttattcgt ttagggttaa
     5581 tctggttctt agtaacattt attatttatc caaactttga tctagtagtg aatgtatttg
     5641 taaaaggagg agaattttcc cttgatgctg tacatcgtgt tctaaaatct cagagggcac
     5701 ttcagagtat tatgaacagt tttaagttag cattttcact cattattaca gttaatgtcg
     5761 taggtattct ttgtgttcta tttacagagt actttgatat taaaggtgct aaaattttaa
     5821 aattaggtta tatgacctct ttaatttatg gaggagtggt tttagcgact ggatataaat
     5881 ttgtctatgg tccttatgga ttgattacaa aatttttaca aaatgttatc ccttctttag
     5941 actctaactg gtttattggg tatggtgcag tcttattcat tatgacattt tcaggaactg
     6001 ctaatcatac attgttttta acaaatacaa ttcgaagcgt tgactatcac actattgagg
     6061 ctgctcgaaa tatgggagca aaaccattta ctgttttccg aaaagtagtg ttaccaacct
     6121 taattccaac tctatttgca cttactatta tggtttttct tagtggttta tctgcagtag
     6181 cagcacccat gattgttggt ggtaaagaat ttcaaactat aaatccaatg attattacat
     6241 ttgcagggat ggggaattct cgtgatttag ctgccttact tgcaattatt ttaggtattg
     6301 caactacaat tttgcttact atcatgaata agatagaaaa aggtggaaat tatatttcta
     6361 tctctaagac taaagcgcct cttaaaaaac aaaaaattgc gtctaagcct tggaatatca
     6421 ttgctcacat tgtagcatat ggattgttca cagttttcat gcttccacta atttttatag
     6481 tattatactc atttacagat ccagttgcaa ttcaaacagg taacttaaca ttatcaaact
     6541 ttactttaga aaattatcgc ttattcttta gtaatagtgc ggcattctct ccattcttgg
     6601 tcagctttat ttattctatt attgctgcga caacagcaac aattctcgca gttgtatttg
     6661 ctcgtgttgt cagaaaacat aaatctcgtt ttgatttctt atttgaatat ggtgctctac
     6721 ttccttggtt actaccaagt acacttttag cagtaagttt attatttact tttaatcagc
     6781 cacaatttct tgttttgaat cagattttgg taggtagttt ggtaattcta cttattgcat
     6841 atatagttgt aaaaatccca ttttcttata gaatggtacg tgctatttta tttagtgttg
     6901 atgatgagat ggaagatgca gcaagaagta tgggtgcttc acctttttat actatgatga
     6961 aggttatcat tccatttatt ttaccggttg ttctctctgt tattgcttta aactttaact
     7021 ctttattaac tgacttcgac ttatctgtat tcctttacca tcccctagct caaccattag
     7081 gtattacgat tcgatctgca ggtgatgaaa cagcaacatc taatgcacaa gctctggtat
     7141 ttgtttatac aattgttctg atgattattt ctggaacggt attatacttc acacaaagac
     7201 cggggcgtaa agtaaggaaa taatcatgac agccactagt cttgggttat caaatattga
     7261 aatagttgtc aggattgttt tatcagtagt cattggtagt ataattggtt tagagagagg
     7321 gagcaaatcc cagcctgcag gcatccgaac ttatagtatt gtttgtctag ctgcatgttt
     7381 gattatgatg acgaatgaat acgtatctta taaatttggg acaggagatc ctacacgatt
     7441 aggagctcaa gttatatcag gtgtgggttt tctaggcgct ggaacgattc ttattacaga
     7501 taagaagaaa attacaggtc tgacaactgc agcaggcatt tgggcttcgg caggaattgg
     7561 attagctatt ggagtaggtt tttatgaggg agctctttta gtagccattt ctgtttgggg
     7621 tgtgatatcc atgttccaac cactaaaaaa atatctgcaa aatcgttcta aaatgattga
     7681 attgtatata gtagttaaat ctacagaagc ctataatcgt gtattggttt attgtgcaga
     7741 aaatggtatc agaatgaccg attcaagaac agcgtttgga gatgttaatt ctgacagaat
     7801 tgaatacttt gatgttccgg acaaaaaaat agcgtcattt attactctgg aattatcagg
     7861 tagatttgaa catcttcgac tgatggaaga aattgctaat attgtaggtg ttatttatgt
     7921 cgaagaaatt agctgaaatt tagtaaacaa agggacagat gtttttgtcc ttttgttttt
     7981 tagatgtttt aatcatctaa tttttgagta gatttttgct cagaggtttt tatgaaagat
     8041 tataaaatca attttgattt aggtaaaata gaatatt
//
LOCUS       DAVKUR010000069         8047 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKUR010000069 DAVKUR010000000
VERSION     DAVKUR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.069"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            118..2751
                     /gene="polA"
                     /locus_tag="VW749_001893"
     CDS             118..2751
                     /gene="polA"
                     /locus_tag="VW749_001893"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0175881.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVGTEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2836..3273
                     /locus_tag="VW749_001894"
     CDS             2836..3273
                     /locus_tag="VW749_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0175882.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(3509..4519)
                     /locus_tag="VW749_001895"
     CDS             complement(3509..4519)
                     /locus_tag="VW749_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0175883.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            4668..5837
                     /locus_tag="VW749_001896"
     CDS             4668..5837
                     /locus_tag="VW749_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0175884.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5834..6604
                     /gene="recO"
                     /locus_tag="VW749_001897"
     CDS             5834..6604
                     /gene="recO"
                     /locus_tag="VW749_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0175885.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6601..7593
                     /gene="plsX"
                     /locus_tag="VW749_001898"
     CDS             6601..7593
                     /gene="plsX"
                     /locus_tag="VW749_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0175886.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            7599..7832
                     /locus_tag="VW749_001899"
     CDS             7599..7832
                     /locus_tag="VW749_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0175887.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            7878..8047
                     /locus_tag="VW749_001900"
                     /pseudo
     CDS             7878..8047
                     /locus_tag="VW749_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2287 a         1487 c         2063 g         2210 t
ORIGIN      
        1 taaatctagg tttactaaat tctctggctc tatctattta ttcggaaaaa gtttgaaaaa
       61 tacttgctct agctcttccc aatggtattt tttgattctt tcctttataa tgggtgtatg
      121 gataagaaaa aattattatt gattgatggg tcttctgtag cttttcgggc gttttttgcg
      181 ctgtatcagc agttggaccg ttttaagaat gcggctggtt tgcataccaa tgcgatttat
      241 ggttttcagt tgatgttgag tcatttgttg gagcgggttg agccgagtca tattttggtg
      301 gcttttgatg cgggaaagac gaccttccgg acagagatgt atgcggacta taagggtggt
      361 cgggccaaga ctcctgatga gtttcgtgag caatttcctt tcattcgtga gttgctggat
      421 catatgggga ttcgtcacta tgagctggct cagtatgagg cggatgacat cattgggacg
      481 ctggataagc tagcagagca ggatggtttt gatattacca ttgtcagtgg ggacaaggat
      541 ttgattcagc tgacggatga gcatacggtg gttgaaattt ccaagaaagg tgtggctgag
      601 tttgaggcct ttacgccaga ttacctcatg gaagaaatgg gcctcacacc agctcagttt
      661 atcgatctca aggcgctcat gggtgataag tcggataata tccctggggt gaccaaagtc
      721 ggtgaaaaga cgggtattaa gctcttgctg gagcatggtt cgcttgaggg gatttatgaa
      781 aatattgatg gaatgaagac ttctaagatg aaggaaaatc tcatcaatga caaggaacag
      841 gcctttttgt ctaaaacact agcgaccatt gataccaagg caccgattgc gattggttta
      901 gaggacttgg tctatagtgg tccagatgtt gaaaatcttg ggaaatttta cgatgagatg
      961 ggcttcaaac agctcaagca ggctttaaat gtgtcgtcag ctgatgtggc tgagggtttg
     1021 gattttacta ttgttgacca aatcagtcaa gatatgctga gtgaagagtc tatcttccac
     1081 tttgagcttt ttggtgagaa ttaccatacg gataatttgg ttggatttgc ctggtcttgt
     1141 ggggataagc tctatgccac agacaagctt gagctgttgc aagacccgat tttcaaggat
     1201 ttcttagaaa aaacatctct gagagtttat gactttaaga aggttaaagt tcttttgcaa
     1261 cgttttggtg tggatttgca ggcgcctgct tttgacatcc gtttggctaa atacctcctt
     1321 tcgactgtgg aggacaatga aattgcgacc atcgctagtc tttatggtca gacttacttg
     1381 gttgatgatg aaactttcta cggtaagggt gttaaaaagg ccattcctga acgtgagaaa
     1441 ttcttggaac acttagcttg taaacttgct gttttggtag gaacagagcc tattttactt
     1501 gaaaaactca gcgaaaatgg gcaattagag cttctttatg atatggagca acctctggct
     1561 tttgttcttg ccaagatgga aattgctggg attgtggtca agaaagagac cttgcttgag
     1621 atgcaggctg aaaatgagct tgtcattgaa aaactgactc aagagattta cgagctggct
     1681 ggtgaggagt ttaatgtcaa ctcgcctaag cagttgggcg tgcttctctt tgagaaattg
     1741 ggacttcctc tagaatacac taagaaaacc aagacaggtt attcgacagc agtggatgtg
     1801 ttggagcgtc tcgctcctat tgctccgatt gttaagaaaa tcctggatta ccgtcaaatt
     1861 gctaagattc aatctactta tgtaattggc ttgcaggact ggattttggc tgatggaaag
     1921 attcatactc gctatatgca ggatttgacc cagaccgggc gtttgtctag tgtggatcca
     1981 aacttgcaaa atattcctgc tcgattggaa caagggcgct tgattcggaa ggcttttgtg
     2041 ccagagtggg aggatagtgt gctactcagc tctgactatt cacagattga attgcgcgtt
     2101 ttggcgcata tttctaagga tgagcacttg attaaggcct tccaagaggg ggcagatatc
     2161 catacttcga cagccatgcg ggtctttggc attgagcgtc ctgataatgt gactgcaaat
     2221 gaccgtcgca atgccaaggc agttaacttt ggagtggttt atgggatttc agactttggc
     2281 ttgtctaata atttgggaat tagtcgtaag gaagccaaag cctacattga tacctacttt
     2341 gaacgttttc caggtattaa aaactacatg gatgaagtgg tgcgggaggc gcgtgataag
     2401 ggctatgtag agaccctctt taagcgtcgc cgtgagttgc cagatatcaa ttcgcgcaac
     2461 ttcaatattc gtggttttgc ggagcgaact gctatcaact cacctatcca gggttcggca
     2521 gcagatattc tcaagattgc catgattcag ctggataaag ccttggttgc aggtggttat
     2581 cagactaaga tgctgttaca agtgcacgat gaaatcgtcc ttgaagtgcc taaatctgaa
     2641 ttggtagaga tgaaaaaatt ggtgaaacaa accatggaag aagccattca actcagtgtt
     2701 cctcttatcg cagatgagaa tgaaggggca acctggtacg aggctaaata aaaagggggc
     2761 tagtcctcct tttttgtagt agaattctgc aaaccttttc aaaatgtgct atactgatga
     2821 aaaaggagga tttctatgag tcaagaattt atcaatccaa gtgatggcgt gattcgtcag
     2881 tatctcgcaa cgagtaaaac ccttgctgtg gtgggtttgt ctgaccgtga agaaacaact
     2941 agcaatcgag taacaaagga aatgcaggct cggggctata aaatcatccc agtcaatccc
     3001 aaggcggcag gtggcgaaat cttgggtgaa aaggcttatg ctagcctcgc tgaaattcct
     3061 tttcctgtag atattgtcaa tgtttatcgt cgcagtgaat ttctgcccga tgtggcgcgt
     3121 gattttctca aagctgatgc caagattttt tgggcacagc taggacttga aagtttagaa
     3181 gcgaaagaga ttttgcgtga tggtggatgt gatgatatcg tgatgaatcg ctgtatcaag
     3241 agagaacata ctcgcttgat tgaggaagca taagaaaaag gtagctgatg ggctaccttt
     3301 tgtgttatac tcaatgaaaa tcaaagagca aactagcaaa ctaggaaact agccgcgggc
     3361 tgctcaaaac actgttttga ggttgtagat agaactgacg aagtcagctc aaaacaccgt
     3421 tttgaggttg cagatagaac tgacgaagtc agtaacatat atacggcaag gcgacgttga
     3481 cgtggtttga agagattttc gaagagtatt agaaaatgcc gataagggtc tgcataccaa
     3541 gagtggtgag gatgatggca atccagcaga tggctccgag aacaatggat tttccactgg
     3601 atttgaccat agcgaccaga ttggttttga gaccgatagc actcatggcc atgacaatga
     3661 ggaatttaga gagttgtttg agaggggtaa agaaactact agacacaccg agagaggtca
     3721 gaagggtggt taggagcgat gcaaggataa agtaaaggat aaaaagtggg aagacttttt
     3781 tcagttgtag gctttgcttg ttttcttgtt ggcgactttg ccagtaggat agaaagagcg
     3841 tgatagggat aatggccaaa gtacgtgtga gtttaacaat ggttgcagac tcgagggtat
     3901 tgctttggta aagactgtcc caagcgctgg cggcagccgt tacagaggaa gtgtcgttga
     3961 ccgcagtccc tgcaaagagg gcgaagcctt cattggatag atgaagccag gtgccgaggg
     4021 ttggaaagat gagcgcagcc aagacattga agaaaaagat aacggaaatg gcttgggcta
     4081 cttccttttc cttagcatca ataacgggcg ctgtcgctgc aatggcagaa cccccacaga
     4141 tagaagaacc tactccaacc aaggtagcca gttttgtatc cagtgcaaag aaacgctgga
     4201 agaggtaggc aataatcaga gctattgaga tagtggacag gatgacaggg agtgaagatt
     4261 ggccaactgc gaagacctgc gagatattga gaccaaaacc aagcaagaca acggcatatt
     4321 ggagcaactt cttggaacta aaggtcaaac cagcatccag ttgtttatag gacgagagaa
     4381 agggatgtag gagcatgcct atgaaaatgg caaaaacggg cgcgccaatc acagggaaga
     4441 atcctcctaa gtaccaagat aggatggaaa tgagaaggca ggccaagata cctgctccat
     4501 tttttgatag aaatgacata aaaacctcca aataaaatct attaccatta tagacctata
     4561 aacaggaaaa gtaaaataga aagtggaaag ctattctcta atgtattttt gcggtcgggg
     4621 ggcttttgta gtataataga gatacgtttt gaaagtagga ggtatctatg gacttaacta
     4681 agcgctttaa taaacagtta gataaaattc aagtttcgtt gattcgtcag tttgaccagg
     4741 ctatttcgga gattcctggg gtcttgcgtt tgaccttggg ggaacctgat tttacaacgc
     4801 cagaccatgt caaggaggcg gccaagcgag cgattgatca gaaccaatcc tactatacag
     4861 ggatgagtgg tctgctgact ctacgtcagg cagccagtga ctttgttaag gaaaagtacc
     4921 aactggacta tgctcctgaa aatgaaatct tggttacaat tggggcgaca gaggctttat
     4981 ctgcgacttt gacggctatt ttggaagagg gagacaaggt acttttgcca gctcctgctt
     5041 atccaggcta tgaaccgatt gttaacttag ttggggcaga aattgttgag attgatacga
     5101 ctgaaaatgg ttttgtcttg actcctgaga tgttggagaa ggccattttg gagcagggtg
     5161 ataagctcaa agcggttatt ctcaactatc cagccaatcc gacaggaatt acctacagtc
     5221 gagagcagtt agaggccttg gcagctgttt tacgcaagta cgaagttttt gttgtctgtg
     5281 atgaggttta ctcagaattg acctacacag gcgaagccca tgtgtctcta ggaacgatgt
     5341 tgagagacca ggctattatt atcaatggtt tgtctaaatc gcatgccatg acaggttggc
     5401 gtttggggct gattttcgct ccggcgacct tcacagccca gttaatcaag agtcaccagt
     5461 acttggtcac tgccgcaaat accatggcgc aacatgctgc ggtagaagcc ttgacggctg
     5521 gtaaaaatga tgcggagccc atgaagaagg aatatatcca gcgtcgggac tatatcatcg
     5581 aaaaaatgac tgctcttggt tttgagatta tcaaaccaga cggtgccttc tatatttttg
     5641 ctaaaattcc agcgggctac aatcaagact cctttgcttt tctgaaggat tttgctcaga
     5701 agaaggccgt tgcctttatc cctggtgcag cctttggacg ttacggggaa ggctacgtcc
     5761 gcctatctta tgcagccagc atggagacta tcaaagaagc catgaaacga cttgaggagt
     5821 acatgagaga agcatgattc agtctatcac gagtcaaggc ttggtgcttt acaatcgcaa
     5881 ttttcgtgag gatgacaagc tcgtcaaaat ttttacagag caggttggca aatgcatgtt
     5941 ttttgtcaaa cacgctggtc agtctaagct ggcgcctgtt attcagccct tggtgctggc
     6001 acgatttctc ttgcgaatca atgatgacgg actcagttac atcgaagact atcatgaggt
     6061 catgactttt cccaagatta atagtgacct ctttgtcatg gcctatgcga cctatgtggc
     6121 agctcttgca gatgctagtt tgcaggacaa tcagcaggat gctcccttgt ttgctttttt
     6181 gcaaaagact ttggagttga tggaagcagg cttggattat caggttttga ccaatatttt
     6241 tgaaattcaa attttgactc gatttggaat cagcctcaat tttaatgagt gtgtcttctg
     6301 ccatcgggtt ggtcaggctt ttgacttttc tttcaaatat ggagcctgcc tctgtccaga
     6361 gcattatcat gaggataaga gacgttgtca tctcaatccc aatatcccct atctgctcaa
     6421 tcaatttcaa gctattgatt ttgagacttt ggagaccatt tcgctcaagc ctggaatcaa
     6481 gcaagagcta cgccaattta tggatcaatt atatgaagag tacgttggga ttcacctaaa
     6541 atcaaagaaa tttattgatt ccctagcaga ctggggacaa ttactaaaag aggaaaagaa
     6601 atgaaaaaaa tcgcagtaga tgccatgggg ggcgattacg cacctcaggc cattgttgag
     6661 ggtgtcaatc aagccctatc tgacttttca gatatcgagg ttcaacttta cggagatgaa
     6721 gctaaaatca agcaatatct gacagcgaca gagcgcgtca gcattatcca tacggatgag
     6781 aagattgatt cggatgatga acctacgaga gctattagga ataagaaaaa tgccagtatg
     6841 gtattggcag ccaaggctgt caaagatggt gaagcagacg ctgtcctttc ggctgggaat
     6901 acaggtgcct tgttggcagc aggattcttc atcgtgggtc gtatcaagaa tatcgaccgt
     6961 cctggactca tgtctacctt gcctaccgtt gatggaaaag gttttgacat gctagacctt
     7021 ggtgccaatg cagaaaatac agcccagcac ctccatcaat atgcggttct aggttccttc
     7081 tatgctaaaa atgtccgtgg cattgcgcaa ccacgcgttg gtttgctcaa caacggaaca
     7141 gagagtagca agggcgaccc gcttcgtaag gaaacttatg aattactggc ggctgatgaa
     7201 agtttgaact ttatcggaaa cgtggaagcg cgtgatttga tgaatggcgt tgcagatgtt
     7261 gttgtggcag atggtttcac gggaaacgct gtgctcaaat ccatcgaagg gacagctatg
     7321 ggaatcatgg gcttgctcaa gacagctatt acaggtggtg gtcttcgagc gaaactaggt
     7381 gccctccttc tcaaggacag cctcagaggt ttgaaaaaac agctcaatta ttcagatgtt
     7441 ggtggagcgg tcttgtttgg tgttaaggca cctgttgtca agactcatgg ctcaagcgat
     7501 gccaaggctg tttatagtac gattcgccag attcgtacca tgctagaaac agacgtagtt
     7561 gcccagactg cgcgtgaatt ttcaggagaa taaaagagat gacagaaaaa gaaatttttg
     7621 accgtattgt gaccattatc caagagcgac agggagagga ctttgtcgtg acagaatcct
     7681 tgagtctgaa agacgatttg gatgcggatt ctgttgactt gatggagttt atcttgaccc
     7741 tggaagatga atttagtatc gaaatcagcg atgaagaaat tgaccaactc caaaacgtag
     7801 gagatgtggt taaaatcatt caaggaaaat agcaatcgga gttccaagtc aacggaagta
     7861 gatggttttt agaaatgaga aatatcggac aagctggtaa aatcttggct gacagtggtt
     7921 atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca
     7981 agccgctaac agttgaagat aaagcctgta atcatgcgct atctaaggag agaagcaagg
     8041 ttgagaa
//
LOCUS       DAVKUR010000070         7732 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKUR010000070 DAVKUR010000000
VERSION     DAVKUR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.070"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(174..1589)
                     /locus_tag="VW749_001901"
     CDS             complement(174..1589)
                     /locus_tag="VW749_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0175888.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1602..3440)
                     /locus_tag="VW749_001902"
     CDS             complement(1602..3440)
                     /locus_tag="VW749_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0175889.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDESVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3458..4300)
                     /locus_tag="VW749_001903"
     CDS             complement(3458..4300)
                     /locus_tag="VW749_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0175890.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLT
                     KNLD"
     gene            complement(4600..7278)
                     /locus_tag="VW749_001904"
     CDS             complement(4600..7278)
                     /locus_tag="VW749_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0175891.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFDGDSEFFLCKRLKDKSQFVMERS
                     RFEEMFQLQSSHLTTQEKLQLFTSVFAGRYDVYAKNFINEQGKIQYFPSYDYGWKQLP
                     PEKRSFQTLTNSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKGLKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVVVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLIEDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYDAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7527..>7732
                     /locus_tag="VW749_001905"
     CDS             7527..>7732
                     /locus_tag="VW749_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0175892.1"
                     /translation="MKLTYDDKVQIYELRKQGYILEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMIH"
BASE COUNT         2554 a         1600 c         1072 g         2506 t
ORIGIN      
        1 accaatctat cctaagttaa ctatttataa tcggctctct gtaacaaaat taaattaatt
       61 aatcccccta taaaataaag aggtttagaa tttgatgtct tccaaacctc tttatttcat
      121 attcaatgag atgttgcctt aaccgtgata atatctaatc atcaataaac aaactatttg
      181 aataaggatt ctccatttga ttcaatcact cctttatacc aagtaaagga cattttctta
      241 tatcgattga atgtgccatt tccatcatca tttcgatcaa cataaatgag accgtacctc
      301 ttagaaagct gtgcagtgga catagaaacg cagtcaatac atccccaaga cgtatagccc
      361 ataatttcca caccatcttg tagagcttca gctacttgca ataaatgttc tttcatatac
      421 tgaattctat aatcatcttg gactgttaag ttattaaatt catcttttat tagttgatct
      481 ttagcaccta atccgttttc cactataaat aatggaattt gataacggtc ataatatcta
      541 tttaaaatta tacgtagtcc aattggatca atttgccatc cccactcaga agactctaaa
      601 taaggattta ctaagccacc aataatattc ccttctcctg aattatactg tgttggaaga
      661 gcagattgag tcacactcat gtaatagcta aaggataaaa aatctacggt ataatttttt
      721 aataactttg catcttcagc tgcaaactct atgttaatgt cattttcctt aaaatatctt
      781 tttgcataat tcggataata acctctaaca tgcacatctg aaaatagata atttagattc
      841 tcatactcat gagtcgccca tacatctttt ggatttggag tcattggata agctggcata
      901 gctaatacca tacaccccac cttaaactct gaattaatct cacgagcaat ttttgtaacc
      961 aaactcgagg cgactaattc atgatgtata gcttgatata attcttgttt cgaaagattc
     1021 tccttaggta tatctattcc tccactagta aacggtaatt ccaaaacaga gtttacttcg
     1081 ttaaatgtaa gccaatattt aactttatct ttataccttt ctaaaactgt tcgagcaaat
     1141 ttttcataaa aatgaatcat tctcctatca atccatccat gatattttct tgctaaatat
     1201 aatggagtct catagtgtga aagagttaca agtggttcta tcccgtgagc atgtagttca
     1261 tcaaacaatt catcataata tttcaaccca gcttcgttag gttcttcctc atctcctttt
     1321 ggaaaaattc tactccatgc aatagaagta cgaaaaacat taaagcccat ttcagaaaac
     1381 aaggatatat cttccttata tttatgataa aaatcaatac ctatcaattt taagttatct
     1441 tctgtaggat tttctgttgc ttctcctaat ccacctttgg gtaacacatc ctgaactgat
     1501 aagcccttac catcttcatt atatgctccc tctacttgat tagctgcaac agctccaccc
     1561 caaagaaaat catctggaaa aatggtcata actttcctcc attataatat taccagtaat
     1621 tccttagaat gctcgattgt ctgattatta ggtaatacta atacatctag aaaatcattg
     1681 gtattcgtta caattactgg tgtaactgtt tcgtagcctt tagtcttgat taaattcaag
     1741 tccatttcaa aaatcaactg atttttgaaa actctgtctc cttcttctac atgactaata
     1801 aaaccttgac cttttagctc aacagtatct aatccaatat gaattagtaa ctcaacactc
     1861 tcatcactct tcaatccaat tgcgtgctta gtcggaaaaa tatttgtaat tttcccatca
     1921 aatggtgcat aaaccttacc ttcacttgga ataatcgcta ctccgtctcc aattagttta
     1981 tctgaaaatg ttttatcctg gacatcgctt aacggaatga tttctcctga tataggagaa
     2041 aatatcattt ttttatttga aactccagct ttaacttcta aattgctaga actctcttct
     2101 tcatcgattc caaatatata agctaataca aaggtaataa caaccgaaat aaccgccaca
     2161 attaaagcat ttacaatatt tgatggtaca tcagaataaa taaattgagg caacgctatc
     2221 aaagatggga cagcaaatag atacgcttta acactagtaa gacctgcaaa taatcccgct
     2281 aatccaccac caatcatagc tgcataaagc ggttttttat attttaaagt cacaccatat
     2341 aatgcaggtt cggtaatccc tgcaagtaag gctgagaaac ctgctgcaaa agcaatttgt
     2401 tttgtattat tatttttact ctttaatgca acagccatcg aagcagcccc ttgagctaag
     2461 tttgacccta acattgctgg aagaattaat acgtctggag tagcaataga tgccgccaaa
     2521 aaaataggtg caaaagccca atgcattcca gtcataacaa taaatggcat aatagcacca
     2581 agaatagcta atgtaagcca tccagctaca tcatacattt gcccaactag atttgataat
     2641 ccttcaccaa caattactcc aataggcccg actacaacta aggcaataca gcttgatact
     2701 aataatacta gcgtaggttg caaaaaactc ttagtaacag ctggtgttaa tttagcaatc
     2761 attttttcaa tatatttcat caaccaaacc ataataagaa ttggaacgac tgacgaacca
     2821 taactagctg gtatcacagg tacaccaaat aaactaagag gattccctga ttgcaccatt
     2881 tgaacaaaat ttggatggag aagtacacct gctacagaca tagctaatgt agatgttact
     2941 tttaattttt gtgatgcaga ataagctaat aacagcggta agaaataata tggagcatcc
     3001 ccaaaaaatg tcaaaaaagc aatagtctga gaatctgatt gcaatatacc aagcattggt
     3061 aaaataatta ccaagacttt cagcatacct ccccctaaca ttgctggaat gattggagtc
     3121 atggaaccag cgatatactc aatgattctt tctaaaatat tccctttgtg cccttgaaca
     3181 actgaatcgg attcaaaatt gccaagttta acgaattctt tataataatt agctacatca
     3241 ttaccaagta taatttgata ttgtccattc tttttcataa tacctattac acctggtatc
     3301 ttcttcacat catcatcatt gactaaattt tcatctttta attctaatct taaacgtgtt
     3361 acacaatggg taactctatt gacatttttt tcacctccaa ttacatcgag gattttttgt
     3421 accttatctt tataactcat ggtattctcc tattctatta atctaaattt tttgttaagc
     3481 gacgaatatg agccatcaaa taaactaatt cactagaagt cagcaaataa ttgtactcag
     3541 tttgtataaa cattgccacc tgttcaccac attcatattc tctaggatat ttatttttca
     3601 ttaatgctaa caagtcttca tcatcatcat cgtcacaata agttgtattt tcaaccaagc
     3661 gatgggcaaa taattttata tgagttatga atctataata atcaatagaa tcttggttaa
     3721 actcagtaca atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt
     3781 tatacgactc ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg
     3841 cagcttcgtc aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt
     3901 tcccaagctc aaattcttct ttataatatt tcgagatttc ccagcgtagg ggattcgaaa
     3961 taataactcc ttctttataa cgttctatac tcgaagaaat atgatccgtt agatttatat
     4021 agataatctc atcaaaatta ttacctaatg ttattttacc tagattaatt attttttcgg
     4081 tgatgtacac caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatattat
     4141 ctctattttt gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccaattt
     4201 ttcttccaaa agctattccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg
     4261 caattacggc attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata
     4321 aaaggaacct acttaaaaac atcaagaaac ttcttctgat gtgattaaat aggttcctgc
     4381 tcacttgtat tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa
     4441 ataattaata actctgtaac cattttcatt ttaagatatt tcaatctatt tgtcaagtac
     4501 ttgtagaaat ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa
     4561 gaaatgaaaa tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag
     4621 ttcagaaact atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa
     4681 taatggcatt gcatcatacc aaacaatagt cttattcacc aaaagaatag gcgttactat
     4741 ttttgattga gtaaaagaca ctttaatttt ctggctcttc aactggtcta gccatgcttt
     4801 atttgcaacc gtctctggta tacatatctc aatttgacta atcctaaatt cttttagaaa
     4861 attcatcagt tttgtctggt gcacataagg taaaataagc agacattcct gtctttcccc
     4921 tgctaagtcc tctatcaaca ccttctcata tctactatca acataaacga attgtttctc
     4981 ctcaccctca atggcacgat aatccatctt tcgataagct acttgtcgtt tctgaaacat
     5041 cttttctaaa taaggaacat gaatatccac ataatcgaaa atacgcacca aagacttatc
     5101 cttgtagttt ctatgaatcc gacctgcata ctgaattaaa ttatttttcc aagaaaaggg
     5161 tgctgccaag ataagcgtgt ccaactgagg taagtcaaaa ccttcgccaa tgtattttcc
     5221 agtagacaac aaaacaaacc ctttatctaa ctgttctaac gtctccagta aactcgttct
     5281 ttctcggact ttggtttttc cgctaataat gtaacagtca tcaacctctt tctctttcaa
     5341 taacttttca aagacatcta tctgttgaat tcgattaact aaaaccaaga tattccgtcc
     5401 ttctgccact tgggctagaa tatccttgag aatcaactga ttcctcgctg agtctgtagc
     5461 aatccaatca ctgagctgta taaaattact tgctttggtc ttttcaatct ccaaatgacc
     5521 aaaagaagtg aatcttaatt gcaattgccg tttaaaatcc gtttccctct tatcagcagt
     5581 atggagtatc tcaccaattc tctgaaaaac aataggctca tgaccattct tacgctcagg
     5641 cgtagccgtc aaaccgtaaa gatacttccc tctaaactga gcaacaactt tttcaaacat
     5701 caaggcagag acatgatgac actcatccac aatcatcatc tcatactcat ccaaaagact
     5761 ttgactattt tccaacttaa atagagattg aatcataacg acatcaacca gtttactcag
     5821 ccatttctta gtcccaccgt actgtccaac atagccgatt accttttcac gacctgatgc
     5881 cgtataacgg atagcctcct cctcttcgaa agtcaaaaag cagtttaagc gatctagcca
     5941 ttggtctaag agttgcttat tatggactag aataattgtt tttgttttcc gttcagagat
     6001 aagagcagca cctaaaacgg tcttcccaaa accagtctcc gcatgaagta aaccattttc
     6061 tttagaagtc atatctgaca gggctaactc ttgctcaaaa gtgagttctc ccttaaattc
     6121 cacgctaata gacctttgta cctttctcct atcttccaca actacctgct taaatttatc
     6181 ttgcaatgga tacagcaaac ctcttggcaa ccataaataa tgatcggatt ctccaaataa
     6241 atacattctc tcaggaattt gataggttgg ctgtcgcata gcctgcttta aataaaattc
     6301 gggattagaa aatgaagcca tatttttcaa gaaaaacagt gtcttgggtg tcacagacga
     6361 tttttcaagt tggatcatat tggataagac gatcttcaac cccttgtcca attcttgctt
     6421 gcctaactct tcttggatta acagtgccac tttagcagtt gaaaccctct gaatttcttg
     6481 tagatacctc cattggtctt cataaggctg aaactgttca tccacaaaga ccgttcgccc
     6541 ttgatggtaa gcttctcctt gaaaaggcaa ggcaatcaaa tttccaaatc cccccttagg
     6601 aaggacatcc tgatttggaa acatgcgatc aaaagaatca aaggacagtt gcatactttc
     6661 ctgcattgcc agttctatca gtttctttcc aaacaagcga gcctctcgac tcggaatcgc
     6721 ttcctcaaag aagaaccaaa tatggagtcc gtgacccgaa cgagaaatct ctaaatgggc
     6781 ttccatctgg cgttccctgg ctattcttcg aatggttaaa ccagcttctt tccaatctcc
     6841 ttcatcaaaa tccagtacca aaaaatgaca gctatcatct aagtgcatag gaaagatacc
     6901 gatagctgtc tccccacgaa aatgagattt caaaacggag ttcgtcaatg tctggaaact
     6961 ccgtttttca ggtggcaact gcttccaacc ataatcatag gaaggaaaat actgaatttt
     7021 cccttgttca ttgataaaat tcttagcata aacatcataa cgtccagcaa acacggaggt
     7081 aaacaattgt aatttttctt gcgtcgtcaa gtgactactt tgaagttgga acatctcctc
     7141 gaaccgagag cgttccataa caaactgact cttgtcttta agacgtttac acaagaaaaa
     7201 ctcactatcc ccatcaaaag aagaaaagac atcaagcact tctaccacaa ttccatccaa
     7261 agacacaaaa acagccataa gagtcacctc cttgattcct ataggctgat tataacaaga
     7321 atagctgaaa ttgtacacga aaataaaatc cgaatagcac tcattttgta tgcgactaat
     7381 agtccatctc gctccggaat gtacgaggta aatagagttt aaacgagcag tctataaaat
     7441 tcaaaaaacg catattacca aggttgtttt gaactacacc ccaaaagtta gacagaaaaa
     7501 atctaacttt ttggggtgtt tttattatga aattaactta tgatgataaa gttcagatct
     7561 atgaacttag aaaacaagga tatatcttag agaagctttc aaataaattt gggataaata
     7621 attctaatct taggtacatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa
     7681 aaggaaaaaa tcgttactat tctcctgatt taaaacaaga aatgattcat aa
//
LOCUS       DAVKUR010000071         7654 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKUR010000071 DAVKUR010000000
VERSION     DAVKUR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.071"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(3..848)
                     /locus_tag="VW749_001906"
     CDS             complement(3..848)
                     /locus_tag="VW749_001906"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0175893.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1104..2131
                     /locus_tag="VW749_001907"
                     /pseudo
     CDS             1104..2131
                     /locus_tag="VW749_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2432..4321)
                     /locus_tag="VW749_001908"
     CDS             complement(2432..4321)
                     /locus_tag="VW749_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0175894.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGTEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLLGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4459..6024
                     /locus_tag="VW749_001909"
     CDS             4459..6024
                     /locus_tag="VW749_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0175895.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6024..6764
                     /locus_tag="VW749_001910"
     CDS             6024..6764
                     /locus_tag="VW749_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0175896.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6873..7088)
                     /locus_tag="VW749_001911"
     CDS             complement(6873..7088)
                     /locus_tag="VW749_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175897.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         2419 a         1706 c         1355 g         2174 t
ORIGIN      
        1 tcttatacaa ataaacggac aaaactgtaa agtagcaaaa cactaccaag cacgatacgg
       61 tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc tggtcaagaa gcgaatagcc
      121 accatgctga ccgcaaaagc tactcccatc gcgaccaaga gcaaaaacaa ttgcccaaag
      181 ctcaagagtt ctccggcttt cacaaatttg aaaatcttta aggcactagc tccaaacata
      241 acgggaatcc caagatagaa ggtaaattct gtcacaactg aacgactggt tccatttaac
      301 aaaccaccga caatcgttgc acctgaacgg ctagtccctg gtaaaagagc aagaacttgg
      361 aagagtccga tatagaaagc ggtcgtataa ggaagcttgt ccaactctgt tacacttggc
      421 tcgatagcac acgctttatt gcgcttttcc aaatagatga aggcaacccc gtagataatc
      481 aacatgagag caactgaaac catgttatgg aagtgggtat caaaccaatc atcaaattta
      541 aagacaccaa gtaaaggtaa agtagcaatc aagaccttca accatagtct ccaagtctta
      601 cgaacttcct gtttgtcctt agtcggttta aaaggattga gcttgttaaa ataaatcacc
      661 ataactgcta aaatagcacc aagctgaatc acgacattaa acatggacat aaaggcttca
      721 ttttgatttt ggtattggat aaactcctct gctaaaatca agtgacctgt actggaaatc
      781 ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga tagattttaa aatttcaata
      841 agatacatat atttctcctt atattatatt taacgcagtt agctactgcc aaagcccaag
      901 tggtatactt ggaataagcc actgtggatt agttcatttc ctccaatcgc ttgacgattt
      961 ccgaaaggat ctaaccacag ctttttgttt caattggtaa tgagtttgat aacgcataga
     1021 cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg gataaccaag tagacttgaa
     1081 atactatatc tggaggtact cccatgcttt atgtgggcat tgatgtcgct aaaaataaac
     1141 acgatgttac agccttgaat gttcgaggaa aactgttctt aaaccactca ctttttcaaa
     1201 taataaagct ggttttgaac tattagatct gtctcttcga cagctcaacc aagactgtct
     1261 catcgctctt gaagataccg gacattatgc ctttaatcta ctgaacttcc tgcatgaaca
     1321 aggatataaa gtttacacct acactccttt gctcatcaag gaatttgcca aatcattatc
     1381 acttcgcaag actaaaacgg ataagaaaga cgctcatggc atcgctctta aacttctttc
     1441 tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagaactaa aaatactggc
     1501 tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat acactcgttg
     1561 tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag aatataccta
     1621 ccaactcttg acatgctacc ctaatcctca gaaaaggctt gaggcaggat ttgataagct
     1681 gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag tcgcacctcg
     1741 ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaaaca tcaaacatta
     1801 caagaggctc attgacaagg cggaaaaatg tgtcaatgac ttgatggctg agttcaactc
     1861 ggtcatcacg acggttactg ggattgggaa tcgtttaggg gcggtcattt tagccgagat
     1921 tcaaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg gactggattc
     1981 ttctatttat cagtcaggtc agattgattt agctggaaga atggtcaaac ggggttctcc
     2041 tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt cacctgcttt
     2101 taaggcctat cttaagacta agttagaata agaaaaacat tacaatgtag ccatcatcca
     2161 ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct gccatttgac
     2221 gaacaaaaag tgatgtaatt tctgaaatca acacaggatt acctttgaaa aaatggactt
     2281 tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt gaaataagaa
     2341 atagtttaga taaaattatt gacttttctt atagtttgtc tttcttctat cttccattat
     2401 atcatacttt ttcagtctat ggtagctctc tttaaaaggc tccgatactg ccgccacctc
     2461 cgcctccaga gaagccaccg ccagaacttc cacttccaga agatacggag taggtacttg
     2521 ctgtatttgc gacactagca taatggctca tttgcgcgct tgaatgataa aacatactgt
     2581 gccagccata agctacatag agattgatat ctggattttc aacttgaatc tgatgaacct
     2641 tcatcaaatg actaaccttg tccgcatagc caagtaaggt tgcatagacc aagagacgat
     2701 tccaaacaac aatactttcc aattcagcct tatccagtcg tgcaatctca cgtaacatat
     2761 tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga acaccatcac
     2821 gattatctag tcgaagcttc caataataga aaacagacaa aactaaccct agaaaaccaa
     2881 gtattggcaa agggaggtaa agatagccat gaacgtctaa actgtacaag aacaaaccaa
     2941 atccgataaa taggggcagg atagtcaagg cacccatacc cacttgcaag gccttttccc
     3001 caccagttaa aggacgataa taatctggga gcccccagaa ggaaactcgt tttctcactc
     3061 cttcttgcat ctggttcaat acctcttcaa aagaagattt gagttgaagc cctcttgctt
     3121 gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat accttgtaat
     3181 ccgcaaacaa attggaaaga gtttcttctt ttttacctga aaaggctaga tttagacagt
     3241 ctctctcaaa gcttgacaaa ccatcttctt ttactagcct caaaccaact gcatctcctt
     3301 ctgaaatgat agagacattc ccacggtcta tcacatctag caaggtagct tgaataagtt
     3361 gatcaaaggt gaattttcca gctcccttga ccaagggact cacttcctcc aaggaggtcg
     3421 agtagactgc ttctgataaa accataggct ctaattccat tggtggttca tagagacgat
     3481 gatttttggc atatttgact gaaggagtgg tctttcttct ataaataaaa tagaagcaga
     3541 cactcaataa caaggagatg gaaaggatcg aagggaggac ccaagtaagt agttgtttac
     3601 tttgctcttt ttctctaaca atcgagtctt ctatcttatt aaactcttct aatcgattcc
     3661 ctttcaatcc ctgatcccta gcgctagcaa aatcggtccg aggccaatag gcatgcaact
     3721 caactccacg cttagccgga agattgtcta aacggatagt ataatcaagg ttactctttt
     3781 caatcgttcc ctctctaaaa agtttccctg tatggaaaaa gagtttttca gtccccttgt
     3841 ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc agaggttgcc
     3901 aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc cagacgaggt
     3961 caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta taaccatccg
     4021 cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc gcggcctgaa
     4081 tctttggatg agggtcaatg tcaaacccgc taggcatctt accagcacgt ccaagtccca
     4141 cgatttggcc cttaaagtcc tcctcaaact ggtaaactat cttctgtcta aactctgccg
     4201 tattatctgc atgaatatac aaatcccctt gataagagtt tatcttgaaa tcaatggcaa
     4261 aaacagagag tggaagaagg caaaacaagc ctaacaccag taagaaaaaa gtttttttca
     4321 tcaactaagc ccccttttta tctttcttat cattatagca ttttttcgta agtaaaggct
     4381 tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat tttttaatag
     4441 atcagaatag gagaaatcat gagaaaaata tacttatcta ttttcacaag tctcttgctg
     4501 atgctaggac ttgtcaatgt tgctcaagcc gatgaatatt tacgcatcgg gatggaagca
     4561 gcatatgctc cctttaactg gacccaggat gatgatagca acggagctgt caaaatcgat
     4621 gggaccaatc agtatgccaa cggatacgat gttcaaatcg ccaagaaaat cgctaaggac
     4681 ttaggtaaag aacctttggt tgttaaaacc aagtgggaag gtctagtccc tgcccttact
     4741 tctggtaaga ttgacatgat tatcgcaggt atgagtccaa ctgcagaacg caaacaagaa
     4801 attgcctttt cgagcagtta ctacactagc gaaccagttc tactggtcaa aaaagattct
     4861 gcctatgcaa atgctaaatc tttggatgac tttaatggtg cgaaaatcac ttctcaacaa
     4921 ggtgtctacc tttatgactt gattgcacaa atcacaggtg ctaaaaaaga aacagccatg
     4981 ggagacttcg ctcaaatgcg ccaagctctt gaggctggtg tcatcgacgc ctatgtttct
     5041 gaacgcccag aagctctgac tgccgaagcc gctaactcta agttcaagat ggtccaagta
     5101 gaaccaggtt tcaaaactgg ggaagaagat acagctatcg ccattggact tcgtaaagat
     5161 gacactcgta ttagccaaat caatgccagc attgaaacca tttcaaagga cgaccaagtt
     5221 gccctgatgg atcgtatgat caaggaacaa cctgccgaag ctacaacaac tgaagagact
     5281 agcagtagtt tctttagcca agttgctaaa attctttctg aaaactggca acaactcttg
     5341 cgtggtgctg gtatcactct tttaatctct atcgtcggaa ccatcacagg tctcattatt
     5401 ggacttgcca ttggtgtttt ccgtactgct cctctctctg aaaacaaagc catttacggc
     5461 ctacaaaaac tagtcggctg gattctcaac gtctacattg aaattttccg tggtacgcca
     5521 atgattgttc aatcgatggt tatctactat ggaactgccc aagctttcgg gatcaacctt
     5581 gaccgtacac tggctgctat cttcatcgtt tcaatcaata ccggtgccta catgactgaa
     5641 atcgtccgtg gtggtatcct agcagttgac aagggacaat ttgaagctgc gactgctctt
     5701 ggtatgaccc ataaccagac catgcgtaag attgtcctac ctcaggtagt ccgtaacatc
     5761 ctacctgcaa ctggtaatga atttgtcatc aatatcaaag atacatctgt attgaacgtt
     5821 atctctgttg tcgaacttta tttctcagga aataccgtgg caacacaaac ctatcaatac
     5881 ttccagacat ttacaatcat cgccgtgatt tactttgtcc tcaccttcac cgtaacacgt
     5941 atcctacgat ttatcgagcg ccgaatggac atggatacct atactacagg tgctaaccaa
     6001 atgcaaacgg aggatttgaa ataatgacac aagcaatcct tgaaattaaa cacctcaaaa
     6061 aatcctatgg acaaaacgaa gtgctaaaag acatttcact cactgtccac aagggagagg
     6121 tcatctctat catcggaagc tctggaagcg gaaaatcgac cttcctacgc tccattaacc
     6181 tacttgaaac accaactgat ggacaaatcc tttatcatgg acaaaacgtc ctcgaaaaag
     6241 gctatgacct cacgcaatac cgtgaaaagt tggggatggt tttccaatcc tttaacctct
     6301 ttgaaaatct caatgttctt gaaaacacaa tcgtcgctca gacaactgtc ctaaaacgcg
     6361 aacgcacaga agctgaaaag attgccaaag aaaacctgga aaaggtcggc atgggagaac
     6421 gctactggca agccaaacca aaacaactct caggtggtca aaaacaacgt gtggccatcg
     6481 ctcgtgccct ctccatgaat ccggacgcta ttctctttga tgaaccaaca tcagctctcg
     6541 atccagaaat ggttggagaa gtcctcaaaa tcatgcagga cctggctcag gaaggcttga
     6601 ccatgattgt cgtaacccat gaaatggaat ttgcccgtga tgtctctcac cgtgttatct
     6661 ttatggataa gggcgtgatc gctgaagaag gtaaaccaga agacctcttc accaatccta
     6721 aagaagaccg aacaaaagag ttccttcaac gctatctcaa ataaaaagaa aaggctgcat
     6781 caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta tctctactac
     6841 ttgaaggtca agaatccgcc gttatccaaa gattaatctt caaatttttc ataatttttt
     6901 tcatagaaat caattaggcc tagggctgtt tcaaatgaaa tattttttac ttttgcacga
     6961 ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga gatacggtag
     7021 cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc aaagtttgac
     7081 ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac gtttttacta
     7141 cttttgtcaa taaaaaaaca tgtattcaac gaaaataatt agttcagaat tttagcttca
     7201 gaattttctt acttcctttt tgaatccgat aatatatagg ttttactagt ctctacacca
     7261 taaatatttg ctaataaaaa tactgtatta ttaccctctt aaggtgcgaa attattcaag
     7321 ttcttaaaaa atgcttctct atttccgtaa gatagcttat ttcttcgatt taagaactga
     7381 agatgatagt tctaaccttt agaaatccaa gccttcacta gctcaaaaac tcctatcttt
     7441 cttcctcaat aaatcatctg agagataggt attccttatg tccttcaaat tcatcactcc
     7501 tttggatatt gaggtgctag cctagaagca gacacccgat tatctaaacc atccttaata
     7561 aagatgacaa gacagataag ctcagttaat tacttatata tctttttaat atggtatatt
     7621 tgtcaacaaa aagaaatcaa atcatacctt atac
//
LOCUS       DAVKUR010000072         7522 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKUR010000072 DAVKUR010000000
VERSION     DAVKUR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7522
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.072"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(82..504)
                     /gene="nusB"
                     /locus_tag="VW749_001912"
     CDS             complement(82..504)
                     /gene="nusB"
                     /locus_tag="VW749_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0175898.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(497..886)
                     /locus_tag="VW749_001913"
     CDS             complement(497..886)
                     /locus_tag="VW749_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0175899.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(908..1468)
                     /gene="efp"
                     /locus_tag="VW749_001914"
     CDS             complement(908..1468)
                     /gene="efp"
                     /locus_tag="VW749_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0175900.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(1597..3039)
                     /gene="gatB"
                     /locus_tag="VW749_001915"
     CDS             complement(1597..3039)
                     /gene="gatB"
                     /locus_tag="VW749_001915"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0175901.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3039..4505)
                     /gene="gatA"
                     /locus_tag="VW749_001916"
     CDS             complement(3039..4505)
                     /gene="gatA"
                     /locus_tag="VW749_001916"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0175902.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDTDNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSASVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(4505..4807)
                     /gene="gatC"
                     /locus_tag="VW749_001917"
     CDS             complement(4505..4807)
                     /gene="gatC"
                     /locus_tag="VW749_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0175903.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5020..6564
                     /locus_tag="VW749_001918"
     CDS             5020..6564
                     /locus_tag="VW749_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0175904.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            6819..7016
                     /locus_tag="VW749_001919"
     CDS             6819..7016
                     /locus_tag="VW749_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0175905.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            7127..7303
                     /locus_tag="VW749_001920"
     CDS             7127..7303
                     /locus_tag="VW749_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0175906.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
BASE COUNT         2087 a         1488 c         1739 g         2208 t
ORIGIN      
        1 tgaacatcaa aaaagaaagg acgaaatttg tcctttctcg agcttagctt ttcttcaacc
       61 cactacagtt gacaaagagc cttattgttc ttctgttaca aactggctga gcagtccatt
      121 gataaaacgg gcagattttt gatcggagaa gtcctttgca agctcgatag cttcattaac
      181 agcaaccagc tgaggagtgt caaatgaagt gatttcaaag actcccaagc gaaggaggtt
      241 tctctccacg agcgttaagc gttcaatggt ccaacctgct tttaaatgct gagtgatttg
      301 cttatctagt tcttcctttt tagcttgaac accagaaacg aggtctatca aaaaggctgg
      361 aagttgtaca tccgtatatt cacgatcatg agtataggcg aaacgacaag cagtttcgac
      421 atccgtaccg aactcaaggc tcatgagagc ttgaaaagcg catttacgga gttggcgtct
      481 agattctaat agtggactag tcattgagga agtcctcgtc aaatagatct ttcaattctg
      541 gttttggtgt tttatctggg acgatacctg caacgtgaat attgatagca gcgagttcta
      601 catcagccat attacggacg gcatctttga cagctttctg gatagcaacc gctaccttag
      661 gaacttttac tccgtactca aggtagagat agatatctgc tgtgagttct tcgtccacgt
      721 ttttaagata aatgccacgg ccgagtgaaa gttttgaaag ggtatcagac actgatctgt
      781 ttgaaaaaga gtgaacaccc tctacctttg cagtagcgat agcaatgatt ttttcaagta
      841 cacgtggggc gataacgatt tcgccaagtt gttcttcaat tcccatagaa tgacctcttt
      901 ctagagatta ggcacgagaa acgtaagttc cttctgcagt gttgataacg agtttttgtc
      961 ctgcttcgat gaagtctgga acgtttacga caagtccagt ttccatcgtt gctggtttac
     1021 cagaacctgt aacagtagca cctttgatag atggttgagt ttcagcaact gtcaactcaa
     1081 cagtagtagg aacggtgaca ccgatcactt cagttccgta gaattggatt ttcacatcag
     1141 agttttcaag gatgtaaagc aattcgtttt caacattgac tacagggatt tcgtattggt
     1201 cgtaagtttc tgtattcatg aagtatgctg tgtcatccat tttgtacaag tattgagctg
     1261 ggacagtctc gataatagct tgttcaaatt tttcctctgg acggtagctt gtgtcaaatg
     1321 tagaaccagt acggacatca cgcaatttca tacgcatgat cgtgtttcct ttacctggtt
     1381 tgtggtgact agcttccaaa acgcgaatca atttgccgtc agctgtttca aaggtcatac
     1441 cagcttttaa tttacttgct tcaatcatgt ttttacctct ttaataaata ttattactct
     1501 tcattttacc ataaaatact ctggaaataa agccaaaata gttattggga gttggtagag
     1561 aagaaaaaac caaccttagg gctggttttg ttctgtctag ttttctttca acttcgccaa
     1621 ttcctgtgca agtagtttaa gggcaacttg tgggttggct tggcctttgg ttgccttcat
     1681 aaggaatcct gtaaaggcct tgtcggcgtt acgtttgcct gacttgaagt cggcaacagc
     1741 agcttcgtta tcggcaaaga cttggtggat gattgggatc aagatagctg gatctgaaat
     1801 ttgaaccata cctgcttttt ccacgtattc acgcgcgcca ccgccatttt tagctagatg
     1861 gacaaagact ttcttggcaa tcttagatga aatagtaccg tcttcgatga tggtaatcat
     1921 ttcaaccaag ttttctggtg tcaattcgat ttgttccagt gttttacctt cagcattcaa
     1981 gaactgagcg acttcccctt ggagccagtt agagacttgt ttggcatcac cacctagggc
     2041 aacagctttt tcaaagaagt cagaagtgac tttattagca gtcaactgac tagcatcgta
     2101 gtctgataaa ccaaggtcag atacataacg cgcacgacgt tcttttggaa actctggcaa
     2161 ctcagtccgc atttcctcaa tccactcgtc agaaatttca aagaggggta ggtctggttc
     2221 tgggaagtag cggtagtcag cagccccttc cttgacacgc atgaggatgg ttgttttgtt
     2281 agcttcatcg taacggcgtg tttcttggcg gatttgacca cctgagcgaa gaatttcagc
     2341 ctggcgttgg acttcgtatt caagaccttt acgaacgttt gagaaggagt tgaggttctt
     2401 caattcagtc ttggtaccga atttttcttg accataagga cgaagggaga tgttggcatc
     2461 cacacgcata gaaccttctt ccatcttaac gtcagaaatg ccagcgtact ggataacttc
     2521 cttgagggct gtcagataag cataggcttc ttcaggagaa cgcatatctg cctcagatac
     2581 aatctcaatc aagggaaccc cttggcggtt gaggtcaaca taagagtagc catctgtacc
     2641 atgggtgttt ttaccagcgt cttcctctaa gtgggcacgt tcgataccga ttttcttggt
     2701 cgtaccgtct tctagtttga cttcaatcca gccattatat ccgattggtt catcaaattg
     2761 agaaatttgg taggctttgg ggttatcagg atagaagtag ttcttgcggt caaagtgcat
     2821 ctttttgtgg atgtccatgt tgagggcaag agcagccttg ataccggcat caacaacccc
     2881 tttattgaga actggtagaa ctcctgggaa agaccagtca attacgttag tgttggcatt
     2941 ttggtcattt ccgaagtggg cagaagtagg tgagaagatt tttgaattgg tgttgagctc
     3001 tacgtggact tcaagtccga tgactgtttc aaagttcatt agttgtcacc tccaaaaatc
     3061 acgggttgtt gtttgtggta gtctgttgtt gcttcaaaag cagcagcagc ttggtaaatg
     3121 gtttcctcag agtacttggg accaatcaat tggagtccga caggtagacc ttgagagaat
     3181 ccagcaggaa tcgaaattcc aggcagtcct gccaagttta caggtatggt caagaggtcg
     3241 gctaagtaca tggcaactgg gtcatggttg agagaatcca agtcataggc aacacttgga
     3301 gcagttggac ccaaaatcaa atcgtaatcc gcgaagactt tttcgaaatc ttgaatgata
     3361 agtgtacgga cctgtccagc cttcttgtag taggcatcgt agtaacctga tgaaagactg
     3421 aaagtaccca gcatgatacg acgttttacc tcttcaccaa aaccttggct tcggctgttt
     3481 acatagattt catcaaggtt ggttgcatct tctgcgcgat agccgtaacg gataccgtca
     3541 aagcgttgca agtttgatga agcttctgat gaagcgatga tgtagtatac ggcaactccg
     3601 tatttagagt gaggaaggct gacttcttcg acaatagcac caagtttttc aaagtgttta
     3661 gcggcactta gaatggtttc cttaacctct gggttaattc cttcaccgag gtattcctta
     3721 ggcaaagcga ttttcatacc cttgatgtct tggccgattt ttgaagtaaa gtcggcgatg
     3781 cggacagaag cagaagtaga gtctttagca tcttcgctgg caatagcgtt gagcaagagg
     3841 gcattttcct taacagtagg agcaaaaggt ccaatctggt ctaatgagct gccaaaggca
     3901 atgagaccga aacgtgaaac tgttccgtag gttggtttga gaccaacgat tccgttgaag
     3961 gcagcaggtt ggcggatgga accaccagta tcagaaccaa gtgacaagcg aacttgtcct
     4021 gaggctacag ctgcggcaga accacttgat gacccaccag gaaccttgct gtggtcccaa
     4081 gcgtttttag ttgctccgta gtgtgaagtt tcacctgaac cacccatagc aaattcgtcc
     4141 atgttggtct ttccaacgac aatcatgccc ttggtttttg cattggcaac agctgtcgca
     4201 tcaaagattg gctcatagtt gtagagcatt tttgaggcag cagttgtgag aataccgtct
     4261 gtagagatgt tatccttaac agcaagtgga attcctgaaa ggacattgtc agtatcaatt
     4321 ccagcttcat caatggcttt agcttgaaca agagcttgct cctcagcgat ggtgacaaat
     4381 gaattgaggg cttcctcacg agacttgata ttttcaagtg ttgcttgggt caattctgtt
     4441 gcagaaattt ccttagagac aaggagattg tgcaactctt caatagtttt atcgttaaaa
     4501 gtcattaggc atctcctcca tcgtctagga tagctggcac cttgatatag tagttgtctt
     4561 tttcaggtac gtttttaaac aagcgatcac ggtctgttcc ttcttcggcc acatcagggc
     4621 ggagtacagt cttgcggtca gccatagtcg tagtaggtgc gacaccagtt gtgtcaactt
     4681 cgcccagcaa ttcaaccatg tcaacaatct tagacaaggt ggtcgcaaag gcagcagttt
     4741 cttcttcaga gaatcttaat tttgaaagat tggcaacgtg tgttacctct tcttgcgtaa
     4801 ttttcatctt gcatcctttc gtgaaatgat gatttttagt ctgttctatt ttaccatatt
     4861 ttcctataaa taagggaggg ggaagtgaaa agaaatagaa attgaaaaaa atgctaaaat
     4921 ccgatataat ggagtgttga aaggaatggt aaaatccaat gtaaaaatca ttctcagcta
     4981 ttgaaacaag aaaaatagag aatcaaagaa agagaactta tgaatattca agaagaaatt
     5041 aagaaacgtc gtacctttgc cattatctcc cacccggacg cggggaaaac aaccatcact
     5101 gagcagttac tctactttgg gggtgagatt cgtgaggctg gtacggtaaa agggaagaaa
     5161 acagggactt ttgctaaatc tgactggatg gatatcgaga agcaacgtgg gatttctgtt
     5221 acttcatctg ttatgcaatt tgactacgac ggcaagcgcg tgaatatctt agacacgcca
     5281 gggcacgagg acttctcaga agatacctat cgtaccttga tggcggtgga tgctgcggtc
     5341 atggtcgtgg actctgccaa ggggatcgag gctcaaacca agaaattgtt tgaggttgtg
     5401 aaacatcgtg gcattccagt ctttaccttt atgaacaagc tggaccgtga cggtcgtgag
     5461 cctttggatc tcttgcaaga attggaagaa atcttgggca ttgctagcta ccctatgaac
     5521 tggcctatcg ggatggggaa agcctttgag ggcttgtatg acctctataa ccaacgttta
     5581 gagctttata aaggggatga gcgttttgcc agtctagaag acggggacaa actctttggt
     5641 agcaatcctt tctacgagca agtcaaggat gacattgagc ttttaaatga agctgggaat
     5701 gagttttcag aggaagctat tctggctgga gaattgacgc ctgtcttttt cggttcagcc
     5761 ctgacaaact ttggtgtgca gaccttcctt gaaatcttcc tcaagtttgc tccagaacca
     5821 catggtcaca agaaaacaga cggtgaaatt gtggatcctt atgacaagga tttctcaggc
     5881 tttgtcttta aaatccaagc caacatggat cctcgtcacc gtgaccgtat tgcctttgtc
     5941 cgtatcgtat caggcgaatt tgagcgcggc atgagtgtca atctccctcg tactggtaag
     6001 ggggctaaac tatctaatgt tacccagttt atggcggaga gtcgtgagaa tgtgaccaat
     6061 gccgtggcag gtgatattat cggggtttac gataccggta cttatcaggt tggggatacc
     6121 ttgacggttg gaaaaaacaa gtttgaattt gaaccactgc caacctttac tcctgaaatt
     6181 ttcatgaaag tttctgctaa gaatgttatg aagcaaaaat ccttccacaa ggggattgag
     6241 caattggtgc aagaaggagc cgttcagctt tataagaatt accaaacagg tgagtacatg
     6301 ctgggagctg ttggtcaact ccagtttgaa gtctttaaac accgtatgga aggcgaatac
     6361 aatgcggaag tggtcatgag cccaatgggt aaaaagaccg ttcgttggat caagcctgag
     6421 gacttggatg aacggatgtc gtcaagtcgc aatatcttag ccaaagaccg ttttgaccaa
     6481 ccagtctttc tctttgaaaa tgactttgcc ctccgctggt ttgcggacaa gtatccagac
     6541 gtagagttag aggagaagat gtgactcagt accaacaatt ggaactaaag ttccaaattg
     6601 ttggacgcta gtcgctattt ggcgaactag ctaactgcct cactaactac gtttggcaaa
     6661 tgaaatcgat ttgtaaaact ccgtgtcgta atgtaaaaat tgtaaaccgt aatgggactt
     6721 catctaaaat ctccactggt atggttttac gaacgaatag gcgaaaataa tggttacgta
     6781 gaaacatatg atgggaataa aaagaaatga gataaaaagt gaaagaagag aaaaaagcga
     6841 ttgtcttagg tgcagataat gcttatatgg ataaagttga aacaacaata aaatctcttt
     6901 gtgttcatca ttataatctt aagttttatg tttttaatga tgaccttccg cgagaatggt
     6961 tccaattgat ggaaaaaaga ctagagactt tgaatagtga gattgtgaat gtttagattg
     7021 acagtaatat tctgaaaggt tatcgtctcc cctttgaggg actttcatat gcggcttttt
     7081 taggtatttt attccaaagt atgtaagcga gtctcgtgta ctgtatttgg attcagatat
     7141 tgttgtaaga aaatcgatag atgagctgtg ggatttggac ttgacggcta tacccttagc
     7201 tgcagttaga gatgattttt atacacataa ttttaattct ggtgttctgt taatcaacga
     7261 tggcatgtgg agagcagaaa atgtcacgca agacctgatt taagacacaa ataaaaaatc
     7321 ttccaattcc ctgtcaatcg aaagtgatta tgtccccaaa aaatggagag tttgagggca
     7381 attattttga tttcatttga cacgaggagc ccttgaagct gttttgttag ctaaaccaag
     7441 gctagtctta gccttggctc gccagcctaa cagctccaag cctcttatca aatgaaatgc
     7501 ttgtcttaca ctcctcactt tc
//
LOCUS       DAVKUR010000073         7116 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKUR010000073 DAVKUR010000000
VERSION     DAVKUR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.073"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(213..380)
                     /locus_tag="VW749_001921"
     CDS             complement(213..380)
                     /locus_tag="VW749_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175907.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(547..618)
                     /locus_tag="VW749_001922"
     tRNA            complement(547..618)
                     /locus_tag="VW749_001922"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(583..585),aa:Arg,seq:cct)
     gene            complement(660..1007)
                     /gene="rplS"
                     /locus_tag="VW749_001923"
     CDS             complement(660..1007)
                     /gene="rplS"
                     /locus_tag="VW749_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0175908.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1126..1455)
                     /gene="crcB"
                     /locus_tag="VW749_001924"
     CDS             complement(1126..1455)
                     /gene="crcB"
                     /locus_tag="VW749_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0175909.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1449..1823)
                     /gene="crcB"
                     /locus_tag="VW749_001925"
     CDS             complement(1449..1823)
                     /gene="crcB"
                     /locus_tag="VW749_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0175910.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1820..2086)
                     /locus_tag="VW749_001926"
     CDS             complement(1820..2086)
                     /locus_tag="VW749_001926"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0175911.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2202..2645)
                     /locus_tag="VW749_001927"
     CDS             complement(2202..2645)
                     /locus_tag="VW749_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0175912.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSIGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            2749..3684
                     /locus_tag="VW749_001928"
     CDS             2749..3684
                     /locus_tag="VW749_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0175913.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3738..4022
                     /locus_tag="VW749_001929"
     CDS             3738..4022
                     /locus_tag="VW749_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0175914.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4079..4297)
                     /locus_tag="VW749_001930"
     CDS             complement(4079..4297)
                     /locus_tag="VW749_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175915.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(4294..5324)
                     /locus_tag="VW749_001931"
                     /pseudo
     CDS             complement(4294..5324)
                     /locus_tag="VW749_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5666..7012
                     /gene="gdhA"
                     /locus_tag="VW749_001932"
     CDS             5666..7012
                     /gene="gdhA"
                     /locus_tag="VW749_001932"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0175916.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
BASE COUNT         2206 a         1477 c         1292 g         2141 t
ORIGIN      
        1 agagatataa ttcctaaaaa attagacaaa taatttatcc ataagatttg gttctgcatt
       61 acactgaact aaatcttttt atttttaata catttgttat tatataggct tttgttgatt
      121 tatttcttgt tttaattcag tggaatagta acgattcttc ccttttttaa cgctctctgt
      181 tcaataacga tcaattcacc ttgtcacata ccttagccag aaacatccat accaaatctt
      241 tttgaaagct gattaaagct ttgtactttc tttctaagtt catagaactg aaccttaacg
      301 tcatttggca attccataat aaaaataagg acattccaat aaaggaagtc ctttttagca
      361 ctactataaa tcaaagacat ttttatgatc cattttattc tataatcatt gaccaaaata
      421 taatttttgg tcaaaatttg gtcaaaaaaa ttaaaaatgc taaattattt ttaaaaatga
      481 acttgagaaa attgccttca aataaacatt ttgaattttc tttgtctttc tttacattac
      541 taaaaatgcc ccctgcagga atcgaacctg caactactcc ttaggaggga gttgttatat
      601 ccattgaact aagggagcta gataaaaact ctgctgaaaa gcagagtttt ttagtcgaat
      661 taacgacgga tttctttgat acgagctgct ttaccttgaa gagcacgcaa gtagtacaat
      721 ttcgcacgac gtactttacc gtaacgaaca acttcgattt tttcaacacg tggagtgtgg
      781 attgggaaga tacgctcaac acctacaccg ttagagattt tacgaactgt gtagttttct
      841 gagattccag cacctttacg tgcgataaca acaccttcaa aaatctggat acgttcacgg
      901 ttaccttcga caactttcgc gtgtacacga acagtgtcac caggacggaa tgatgggata
      961 tctgtacgaa gttgaccttc agtcaagctt tggattaatg gattcatttt attctcctat
     1021 ctttgtcaat cttgaggaaa tttcctcagc ggataaactg tatttttgtg cgtccatcac
     1081 acacaagata cagtctacca aattttcaca aaaaagtaaa gaaatttata gcaaaattcc
     1141 taaaaaaatc gcaaccaaac cacctatgta agtcaaagtc aggtaagaat aaaagacctt
     1201 cttatcactt aacagtcttt gaagttcgtc attcaaggtc gaaaaagttg ttaaaccgcc
     1261 acaaaatcct gttgctagaa tagcatatac ttccttagac tctacatgat tgtagaatac
     1321 tccaattaaa aaacaaccta aaagattagc tatgagcgtt ccgagtggca atttagaagc
     1381 ttgattgtag cgggaaaaga aataccgtac gagtgctccc aagccacagg cgattgcaag
     1441 atagacgatt accatttctt cctccctaga aaataagcta agagtaggcc tccaccgatg
     1501 ctcaaaagca aatacaggac taaactaaga taacgccctg tatcaagcag cttcacagta
     1561 tcaagcatta ggctggaaaa agttgttaaa cctccgcaaa aacccgtccc cagtgctaaa
     1621 atcaagccct tactagtccc cttatagacc agatagccct tgacaagaaa aatcaagcag
     1681 aaaattccca gatagttgac aaagagagtg ccccaaggaa agtctggact ggctggtaac
     1741 caggtggaaa ctagatatcg gacaagtccg cccaacatag cagctagaaa aattcctagc
     1801 ggataaaatt gttctttttt catttgatat tttgatcctg ataatcacgc gaacgtttga
     1861 gtatgtccga aaaagtcgct acaatagtct cctgatagcg cttgtcctct acacgactcc
     1921 taaccttttc aaaaataact tcttctctct tagtatctaa aatcggttta cctgaagctt
     1981 tcttataagc aaccaccccc tcaactaaat gcattcgttc ttctaacagt ttgacaattt
     2041 ggtcatcgat ttgatcgatt tcttgacgaa taatatctaa atccatacag tctcctcctt
     2101 tatttgaatt attgtatcaa aaagccatca attaggctag taaaatccca actctcgata
     2161 agaaaaatgc actgattgat tacatcagcg cacttttatg cttatactac tttagcaacc
     2221 aattcttctg cgaattgttc caagcgttca atatcttctt cctcggcaga aagatcaact
     2281 ttaacacact ctgaaccttt ttctgctcct attgacacaa agacacggtc aaagtcatca
     2341 acagccttac agaattcatc gtagaaggta tctcctgagc cgaccactcc gtagattttg
     2401 ccattcaagt tgagatctgc taggtcttcg tagaagtcca tcatctcatc tggcaattca
     2461 ccatcaccat aagtataggt cgcaacgata gcgatgtctg cttccaagaa gtctgaagcg
     2521 tcaacagttg tacattcatc aacatcaaca tccaagccca agtcacgtaa tttgtctgct
     2581 acaatatctg caatttcttc ggtattaccg gtcatactgg caaatacaat ttttgctaat
     2641 gccatatcgt cctcctcaat ttatctttct ccattatatc acatcttttt cattttaaaa
     2701 ataaaaattc ttgtgctaca atgaaatgag aaagaattga ggttatttat ggagatttgc
     2761 caacaaattt tagaaaaaat taaagaatac gacaccatta tcattcatcg tcatatgaaa
     2821 ccagaccctg atgccttggg aagtcaggtg ggattgaaag ccttgctgga acatcatttc
     2881 ccagaaaaaa ccatcaaagc cgtcggtttt gatgaaccaa ctcttacttg gatggctgag
     2941 atggatcttg ttgaagatag agcctaccaa ggcgcacttg tcatcgtctg tgatacagct
     3001 aatactgctc gtatcgatga taagcgctat agtcaaggtg attttctcat taagattgac
     3061 caccatccaa atgatgatgt atacggtgac ctgtcttggg tcgatactag ttcaagtagc
     3121 gctagcgaga tgattaccct atttgcccaa acaacccaac tagccttggc agatcgcgat
     3181 gctgagttgc tctttgcagg aattgtcggt gatacaggtc gcttcctcta cccttctacc
     3241 actgcacgga ctcttcgcct ggctgcttat ttgagagaac ataactttga ctttgcggct
     3301 ctcactcgca aaatggacac tatgagctac aaaattgcta aactgcaagg ctacatctac
     3361 gaccatctgg aagtggatga aaatggtgct gctcgcgtta tcctgagtca agaagtcttg
     3421 aaacaataca atgtaaccga tgctgaaact gcagccattg tcggtgcacc tggacgcatt
     3481 gacagagtga gtctctgggg aatttttgtc gaacaggctg atggccacta ccgagttcgc
     3541 ttacgcagta aaatccatcc tatcaatgaa atcgccaagg agcatgatgg tggaggccac
     3601 cctctagcaa gtggtgctaa ttcctatagc ctagaagaaa acgaaatcat ctaccaaaag
     3661 ttaaaaaact tgcttaaaaa ctgataaaat acttgccaaa cttttcagaa tctgatagac
     3721 tagtatggta acaatctatg gctcgcaaag agaccatggc agaaaggaaa tattgcaaaa
     3781 tgaaaaaaga tatccatcca gaatatcgcc cagttgtctt catggacaca actactggtt
     3841 accaattcct tagcggttca acaaaacgct ctaacgaaac agttgagttc gaaggcgaaa
     3901 cttacccatt gatccgtgtg gaaatttcat cagactcaca cccattctac actggacgtc
     3961 aaaagttcac tcaagcagat ggacgcgtgg atcgtttcaa caaaaaatac ggtctcaaat
     4021 aatgataaga gaacagtttc ggctgttctt ttttgtttct tgaaatcaac tgctgttttc
     4081 atgttccaga ctcatctgta ggtttggttt ccatgctact aggcaggaag gaaatagctg
     4141 tttcaacacg tccataatga gctgtactat tgtcacgaac cacactttca ttgatggtcc
     4201 aagtggaatt cattttctta aaagcttctc ggactttttc caaatctttg gaggcaatgg
     4261 cctgctctaa ggtttcaaaa cgaggactta tactcatctg ctttcacaaa gcattctagt
     4321 ccatctccga ttaacgatgg gctttatcac ctccttctcc agtccttgta tgatatctta
     4381 aagttgattc atgacatctt ccaaagtttg aaaggcttta tttttaaatc cacgtttacg
     4441 aatctctttc cacacttgtt caatggggtt catctctggt gtgtacggag gaataaatgc
     4501 aaagccaata ttagtcggaa tctttaaggt acttgattta tgccatatag cattgtccat
     4561 aacgagtaaa agataatcat ctggataagc ttgtgaaagc tcttctaaaa aggcgttcat
     4621 ccactcagta ttacatccac cagctcttaa gaaaaatgat tcgcctgtat gggcatcaac
     4681 agctccataa caatagcgaa attctcgtat atagtgacta tggacatgtg gacctactcc
     4741 tattggagac caacaagatc ccagtttact gattctaccg aaaccagcct catcttggta
     4801 catcgagcga accttatgaa aaggtctact ggttttaaag cgctttcttt tcttcttgaa
     4861 ttgagatttt atttttagac gcgacaatgg tttgagcgtc tgctttctta ggatgttctg
     4921 gacgtggcat aatatttcgc caaccatggc gcttcaacag ttgatagaag gcatcacgtg
     4981 tgtaggaacg atataagcct gaaataaggt attgtaacaa attctcctgc ctctgtagcc
     5041 ttcaaatggc gggcaagaaa ggctttctct tcctcaactg tcatatatgc atggttacga
     5101 ccaccacgtg tttcttgaag gagagagtcg agtccgaact cctcatattt ttttacattt
     5161 cgccaaatcg ttgtttgatt acagtctaaa agctctataa tctctttata agatttgccc
     5221 atcagacgaa atagaacgat ttgaaggcgt ttatgatatt tagctgtacg agagtctttt
     5281 aaaagtgttt tgatggcttg gatttcttct ttagttgatt tcatatcact attatataat
     5341 gctttttgat tttagtctgg tataaatatt gctttcctcc aaaatggtca taattttact
     5401 agcaaatcta acatatcacg gataaattaa caagtgattt ctgaattgct aaacattttc
     5461 ttttcttata gcataccata ctttaagatt ttgtctttga gaaagatatt tccaagaaaa
     5521 acgttcgttt ttttatctat tttcaaaaaa aaccaaaaac tgaattgaaa gaatttttag
     5581 aaaatttctg ttttttcttt acagtgaaaa aaaattctgc tataatgtct tatgtaataa
     5641 aatatgacaa taaaaggaga acgatatgac atctgctaaa gaatatatcc aaagcgtgtt
     5701 tgaaactgta aaagctcgta acgggcacga ggctgaattc ctccaagctg ttgaagaatt
     5761 tttcaacact ttggaacctg tatttgaaaa acaccctgag tatatcgaag aaaatatctt
     5821 ggcacgtatt actgagcctg agcgcgtgat ttctttccgt gttccttggg ttgaccgtga
     5881 tggaaaagtt caagtaaacc gcggctaccg tgttcaattc aactcagctg ttggaccata
     5941 caaaggtgga cttcgtttcc acccaactgt aaaccaaggg atcttgaaat tcctcggatt
     6001 tgaacaaatc tttaaaaatg tcttgactgg acttcctatc ggtggaggta aaggtggatc
     6061 agacttcgat cctaaaggta aaacagatgc tgaagtgatg cgcttctgcc aaagcttcat
     6121 gactgaattg caaaaacaca tcggaccatc acttgacgta cctgctggtg atatcggtgt
     6181 tggtggacgt gaaattggtt acctttacgg tcaatacaaa cgtcttaacc aatttgatgc
     6241 tggtgtcttg actggtaaac ctcttggatt tggtggtagc ttgattcgtc cagaagcaac
     6301 tggttacggt ttggtttact atactgaaga aatgctcaaa gctaacggta acagctttgc
     6361 tggtaagaaa gtcgttattt caggttctgg taacgttgct caatacgctc ttcaaaaagc
     6421 aaccgaactt ggtgcaacag ttatctctgt ttctgactca aacggctatg ttatcgatga
     6481 aaacggtatc gacttcgatc ttttggttga tgttaaagaa aaacgtcgcg ctcgtttgac
     6541 tgagtatgca gctgagaaag caactgctac ttatcatgaa ggttctgtat ggacttacgc
     6601 tggaaactat gacattgcgc ttccatgtgc tactcaaaac gaaatcaacg gtgaagcagc
     6661 taaacgtttg gttgctcaag gcgttatctg tgtatctgaa ggtgccaaca tgccaagcaa
     6721 ccttgatgcc atcaaagttt acaaagaaaa tggtatcttc tacggacctg ccaaagctgc
     6781 caacgctggt ggtgtagccg tttcagccct tgaaatgagc caaaacagcc ttcgcctctc
     6841 atggactcgt gaagaagttg atggacgtct caaagacatc atgaccaaca tctttaacac
     6901 agctaaaaca acttcagaaa catatggtct tgataaagac taccttgcag gagctaacat
     6961 tgctgccttt gaaaatgtag caaacgctat gattgcacaa ggcgtggtat aaaaaaaaat
     7021 tacggaaact gactacccag acgggtagcc agttttttca attcctaaaa tttaagattc
     7081 taataccctt tatgcaaaaa tatagaattc tacctt
//
LOCUS       DAVKUR010000074         6863 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKUR010000074 DAVKUR010000000
VERSION     DAVKUR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.074"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..471
                     /locus_tag="VW749_001933"
                     /pseudo
     CDS             1..471
                     /locus_tag="VW749_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            638..838
                     /locus_tag="VW749_001934"
     CDS             638..838
                     /locus_tag="VW749_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175917.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            863..1279
                     /locus_tag="VW749_001935"
     CDS             863..1279
                     /locus_tag="VW749_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175918.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLDVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1510..2217
                     /gene="ccdA2"
                     /locus_tag="VW749_001936"
     CDS             1510..2217
                     /gene="ccdA2"
                     /locus_tag="VW749_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0175919.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2228..2785
                     /gene="sdbB"
                     /locus_tag="VW749_001937"
     CDS             2228..2785
                     /gene="sdbB"
                     /locus_tag="VW749_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0175920.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2906..4297
                     /locus_tag="VW749_001938"
     CDS             2906..4297
                     /locus_tag="VW749_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0175921.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4440..5357
                     /gene="adcAII"
                     /locus_tag="VW749_001939"
     CDS             4440..5357
                     /gene="adcAII"
                     /locus_tag="VW749_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0175922.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5365..>6863
                     /locus_tag="VW749_001940"
     CDS             5365..>6863
                     /locus_tag="VW749_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0175923.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         2126 a         1247 c         1434 g         2056 t
ORIGIN      
        1 aagttgatag agatagactt aaaaactatc ttactgacaa tccagacgct tatttgactg
       61 aaatagcttc tgaatttggc tgtcatccaa ctaccatcca ctatgcgctc aaagctatgg
      121 gctacactcg aaaaaagaac cacacctact atgaacaaga cccagaaaaa gtagccttat
      181 ttcttaagaa ttttaatagt ttaaagcacc tagcacctgt ttagattgac gaaacaggat
      241 tcgatactta tttttatcga gaatatggtc gctcattaaa aggtcagtta agaagaggca
      301 aagtatctgg aagaagatat cagagaattt ctttggttgc aggtctaaca aatgaatggt
      361 gagttaatcg ctccaatgac ttacgaagag acgatgacga gcgacttttt tgaagtatgg
      421 tttcagaaat ttctcttacc aacattaacc acaccatcgg ttattatagt aaaatggaat
      481 aagaacagga caaatcgatc aggacagtaa aatcgaattc taacaatgtt ttagaagtct
      541 atatgtacta ttctagtttc aatataccat aactgctcct agtcaacctg caagtcctgt
      601 cccagctcca agctcagctc cgactcaaga tcctagagtg gtagcaagcg cttcggctag
      661 ctcaacgagc acacaagctc aagagcaagt tgacaagtct gaacttcgtg ccttgagtca
      721 agagttagac caacgcttga aagctttggc aacagtatct gatccaaaaa tcgatgcaac
      781 caaggctgtc ctcctagatg ctcaaaaagc tccggaagat agtgccttga cagagtaagg
      841 tctgcatact gcagtagagt ctgtgaaggc tgccttggac tctctcaaag atgtgaaagc
      901 aaatgctagc gacagcaagc ctgcacagga caagaaggat gcaaaacaag gaacggaaga
      961 tagtaaggat tcagataaga tgactgaaac aaactcagtt ccggcaggag tgattgtggt
     1021 cagtctactt gccctcctag acgtgattgc cttctggctg attcgccgta agaaagagtc
     1081 agaaatccag caattaagca cggaattgat caaggttcta ggacagctag atgcagaaaa
     1141 agcggataaa aaagtccttg ccaaagccca aaaccttctc caagaaaccc ttgatttcgt
     1201 gaaagaagaa aatggctcag cagagacaga aactaaacta gtagaggagc ttaaagcaat
     1261 ccttgacaaa ctcaagtaaa acatgattta tgaaatgtca gacctaaaag acattttcgt
     1321 tcacaaaagc agtgacgagt aatccttgtc gttgcttttt ggctattttg ggggataaga
     1381 tccgccttga ctagcaaaag aaaagattgg tccaatagtg cccgatacga ttttgcgtag
     1441 cagaaagctt acaaataaaa ttgaatatag taaaatagga ttagaattat taagaaagtt
     1501 ggttctttat tggaaacgat agtattttta atctctgttt ttctagcagg tgttttatcc
     1561 tttttttctc cttgtatttt tcctcttctg ccagtctatg ctgggatttt attggatgat
     1621 caagaaagtg caaaaagctt ttctttgttt gggagaaagg ttctctggtc aggcttgatt
     1681 cgaacacttt gctttatcgc tggtatctct ctcattttct ttattctagg ctttggtgct
     1741 ggttactttg gtcatattct ctatgcaaat tggtttcgat atgtcatggg agctattatt
     1801 atcattttgg gtcttcacca gatggaaatt tttcatttga agaaattaga agttcaaaaa
     1861 agttttacct ttaaaaaatc agattctaat cgttattggt cagctttttt acttggtatt
     1921 acctttagct ttggttggac accttgtatt ggtccagttt taagttctgt tttagcactt
     1981 gcggcttctg gaggcaatgg tgcttggcaa ggagcgattt atactctcat ttacactctg
     2041 ggcatggccc ttcctttctt ggtcttggca ctagcttcag gtctagtcat gccatatttt
     2101 agtaaaatca agcgtcatat gatgctacta aagaaaattg gtggtttcct cattgtttta
     2161 atgggaattt tgttactatt aggacaagta aatgttctag ctggaatttt tgaataaagg
     2221 aggacaaatg aaaaaagtaa tgtttgctgg cttaagtctc ttgtcattag ttgtattgat
     2281 ggcctgtggt gaggaagaaa ctaaaaagac tcaagcagca caacagccaa aacaacaaac
     2341 gactgtacaa caaattgctg ttggaaaaga tgctccagac ttcacattgc aatccatgga
     2401 tggcaaagaa gttaagttat ctgattttaa gggtaaaaag gtttacttga agttttgggc
     2461 ttcatggtgt ggtccatgca agaaaagtat gccagagttg atggaactag cggcgaaacc
     2521 agatcgtgat ttcgaaattc ttactgtcat tgcaccagga attcaaggtg aaaaaactgt
     2581 tgagcaattc ccacaatggt tccaggaaca aggatataag gatatcccag ttctttatga
     2641 taccaaagca accaccttcc aagcttatca aattcgaagc attcctacag aatatttaat
     2701 tgatagccaa ggaaagattg gaaagattca atttggtgct atcagtaatg cggatgcaga
     2761 agcagcattt aaagaaatga actagaatcg ataaaatctg attacaagat gtagtcagat
     2821 ttttttagaa aaacatttta taaatattca catatctcct atatttatgg taaaatagaa
     2881 ttatcagttt attttggagt caaagatgaa tatatttaga acaaagaatg ttagtttaga
     2941 taaaacagag atgcataggc atttgaagtt atgggatttg attttgctgg gtatcggagc
     3001 catggtaggg acaggcgtct ttacaatcac aggtactgca gctgcaacac ttgctggccc
     3061 agccctagtg atttcaatcg ttatttctgc cttgtgtgtg ggattatcag ccctcttttt
     3121 tgcagaattt gcctcgcgag tacccgctac aggaggtgcc tatagttacc tctatgctat
     3181 cttaggagaa ttccctgcct ggttggctgg ttggttaacc atgatggagt tcatgacagc
     3241 catatcaggc gtagcttcgg gttgggcagc ttattttaaa ggcttgctct ctcaatacgg
     3301 gatagccttt cctcaggctt taaatggtac ctttaatcct caagcaggga catttgttga
     3361 tttattgcct attcttgtct tggtcttggt gacttcgctt gttttactaa atgccaaggc
     3421 agccttacgc tttaattcga ttctagttat tttgaaattt tccgctttag ctctctttgt
     3481 tttagtagga atttggaata ttaagtttga taattggagc aattttgctc cttacggttt
     3541 tggacaaatc tatggagcta gcactggtat tatggctggt gcgtccttga tgttcttcgg
     3601 ttttttggga tttgaatcca tctctatggc tgtagatgaa gtcaagactc ctcaaaaaaa
     3661 tattcctaga gggattgtct tatcgctttc tatcgtaacc attctctatg ccttggtgac
     3721 ccttgttttg actggtgtgg ttcactatag tcatttaaat gtcgatgatg ccgttgcctt
     3781 tgcccttcgt agtgttggga ttagttgggc agccaactat gtgtcattag tggctatctt
     3841 gaccttgatt acagtttgta tttcgatgac ctatgcccta tcgcgtatga tttacagttt
     3901 agcacgtgac ggcttagtgc ctgctgcctt taaggaactg acgaagacta gcaagatacc
     3961 aaagaatgct actatcttga caggtctagc ttcagcagta gcagcaggaa tgttcccact
     4021 agccagtatt gcagcctttt taaatatttg taccttagcc tacttgatca tgctggctta
     4081 tggtctgatt cgcttacgga aagaaaaagg aatgcccaaa gctggggaat ttaaaacacc
     4141 attggtacct ctgttaccaa ttttatcgat catcatttgt ttatccttca tgttacagta
     4201 taatatgaac acctggattg ctttcctagt tgcgttgtta gtaggaagta ttatttactt
     4261 cacttatggc tataagcatt ctaccataga agaataaagt gaaagtctat tgagttgttg
     4321 acactcagta gatttttata tgtgaaagaa atttcaaatt ttttctaaaa atatcttgac
     4381 agattaaatt ttcaggagta gaatatttac tagttaatta aatggttaag gagttgttca
     4441 tgaagaaaca aaatttattt ttagtcctgt taagtgtctt tcttttgtgt ttgggggctt
     4501 gtggtcaaaa ggaaagtcag acaggaaagg ggatgaaaat tgtgaccagt ttttatccta
     4561 tctacgctat ggttaaggaa gtatctggtg acttgaatga tgttcggatg attcagtcaa
     4621 gtagtgggat tcactccttt gaaccttcgg caaatgatat cgcagccatc tatgatgcag
     4681 atgtctttgt ttaccattct catacactcg aatcttgggc aggaagtctg gatccaaatc
     4741 taaaaaaatc caaagtgaag gtcttagagg cttctgaggg aatgaccttg gaacgtgtcc
     4801 ctggactaga ggatgtggaa gcaggggatg gagttgatga aaaaacgctc tatgaccctc
     4861 acacatggct agatcctgaa aaagctggag aagaagccca aattatcgct gataaacttt
     4921 cagaggtgga tagtgagcat aaagagactt atcaaaaaaa tgcgcaagcc tttatcaaaa
     4981 aagctcagga attgactaag aaattccaac caaaatttga aaaagcgact cagaaaacat
     5041 ttgtaacaca acatacagcc ttttcttatc tagcgaagag atttgggctt aatcaacttg
     5101 gtattgcagg tatctctcct gaacaagaac caagtccacg acaactaaca gaaattcagg
     5161 aatttgttaa gacctataag gttaaaacga tttttacaga aagtaacgct tcttcaaaag
     5221 tagctgaaac tcttgtcaaa tcaacaggtg tgggtcttaa aactctgaat cctttagagt
     5281 cagacccaca aaatgacaag acctatttag aaaatcttga agaaaatatg agtattctag
     5341 cagaagaatt aaagtgagga aagaatgaaa atcaataaaa aatatctagc aggttcagtg
     5401 gcagtccttg ccctaagtgt ttgttcctat gaacttggtc gtcaccaagc tggtcaggtt
     5461 aagaaagagt ctaatcgagt ttcttatata gatggtgatc aggctggtca aaaggcagaa
     5521 aatttgacac cagatgaagt cagtaagaga gaggggatca acgccgaaca aattgttatc
     5581 aagattacgg atcaaggtta tgtgacctct catggagacc attatcatta ctataatggc
     5641 aaggttcctt atgatgccat catcagtgaa gaacttctca tgaaagatcc gaattatcag
     5701 ttgaaggatt cagacattgt caatgaaatc aagggtggct atgtgattaa ggtagacgga
     5761 aaatactatg tttaccttaa agatgcagcc catgcggaca atattcggac aaaagaagag
     5821 attaaacgtc agaagcagga acgcagtcat aatcacaact caagagcaga taatgctgtt
     5881 gctgcagcca gagcccaagg acgttataca acggatgatg ggtatatctt caatgcatct
     5941 gatatcattg aggacacggg tgatgcttat attgtccctc acggcaatca cttccactat
     6001 attcctaaga gtgatttgtc tgccagtgaa ttagctgctg cccaagccta ttggaatggg
     6061 aagcagggat ctcgtccttc ttcaagttct agtcataatg caaatccagc tcaaccaaga
     6121 ttgtcagaga accacaatct gactgtcact ccaacttatc atcaaaatca aggggaaaac
     6181 atttcaagcc ttttacgtga attgtatgct aaacccttat cagaacgcca tgtagaatct
     6241 gatggcctag tatttgatcc ggcacaaata acatatcgta cagtcaatgg tgttgctgta
     6301 ccgcacggag accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa
     6361 ttggctcgta tgattgctgt taagggacaa aatggtgcag tcttgccagg aatgcattat
     6421 ttgaaaccag caccaaaacc gcaagttcaa ccatcaactg agaaaaaaca aactgatttt
     6481 gcagtagaac aggttgttag aaaagttgga gaaggctatg ttgtggaaat tgctggtgtc
     6541 agtcactatg tttttgctaa agacttggct aaggataaga ttgatgctat tgaaaatctc
     6601 ttgtctaaga aaactcaaga gacacatgct ctagttgcta aaaaagaaaa tgtcgctcct
     6661 cgtgaccaag aattttatga taaagcttac aatctgttaa cccaggctca taaagtcttg
     6721 tctgaaaata aaggtcgtac ttctgatttc caagccttag acaaattagc agaacgcttg
     6781 aataatgaat cttctaataa agtaaaattg gtagatgatt tattggcatt cctagcacca
     6841 attacccacc cagaacgcct tgg
//
LOCUS       DAVKUR010000075         6850 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKUR010000075 DAVKUR010000000
VERSION     DAVKUR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6850
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.075"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            102..6536
                     /locus_tag="VW749_001941"
     CDS             102..6536
                     /locus_tag="VW749_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0175924.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARVKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDDRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNLNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2705 a          922 c         1337 g         1886 t
ORIGIN      
        1 ctatttccta gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt
       61 tattatctat tggaagttaa ataaatatgt aaggaattaa aatgaaaaaa agtacagtat
      121 tgtcattaac cacagctgca gttattttag cagcctatgc ccctaatgag gtagtcttag
      181 cagacacatc tagctctgaa gatgctttaa acatctctga taaagaaaaa gtagtattag
      241 ataaggaaac agaaaataaa gagaaacatg aagatattca taatgctata gaaacttcac
      301 aggattttaa agagaagaaa acagcagtca ttgagggaaa agaagttgtt agtaaaaatc
      361 ctgtgacaga caataacact agcaatgaag aagcaagagt caaagaagat tccaatcaat
      421 cccaaggaga tcatacggac tcatttgtga ataaaaacac agaaaatccc aaaaaagaag
      481 ataaagttgt ctatattgct gaatttaaag ataaagaatc tggagaaaaa gcaatcaagc
      541 aactatccaa tcttaagaat acaaaagttt tatatactta tgatagaatt tttaacggta
      601 gtgccataga aacaactcca gataacttgg acaaaattaa acaaatagaa ggtatttcat
      661 cggttgaaag ggcacaaaaa gtccaaccca tgatgaatca tgccagaaag gaaattggag
      721 ttgaggaagc tattgattac ctaaagtcta tcaatgctcc gtttgggaaa aattttgatg
      781 gtagaggtat ggtcatttca aatatcgata ctggaacaga ttatagacat aaggctatga
      841 gaatcgatga tgatgccaaa gcctcaatga gatttaaaaa agaagactta aaaggaactg
      901 ataaaaatta ttggttgagt gataaaatcc ctcatgcgtt caattattat aatggtggca
      961 aaatcactgt agaaaaatat gatgatggaa gggattattt tgacccacat gggatgcata
     1021 ttgcagggat tcttgctgga aatgatactg aacaagatat caaaaacttt aacggcatag
     1081 atggaattgc acctaatgca caaattttct cttacaaaat gtattctgac gcaggatctg
     1141 ggtttgcggg tgatgaaaca atgtttcatg ctattgaaga ttctatcaaa cacaacgttg
     1201 atgttgtttc ggtatcatct ggttttacag gaacaggtct tgtaggtgag aaatattggc
     1261 aagctattcg ggcattaaga aaagcaggca ttccaatggt tgtcgctacg ggtaactatg
     1321 cgacttctgc ttcaagttct tcatgggatt tagtagcaaa taatcatctg aaaatgaccg
     1381 acactggaaa tgtaacacga actgcagcac atgaagatgc gatagcggtc gcttctgcta
     1441 aaaatcaaac agttgagttt gataaagtta acataggtgg agaaagtttt aaatacagaa
     1501 atataggggc ctttttcgat aagaataaaa tcacaacaaa tgaagatgga acaaaagctc
     1561 ctagtaaatt aaaatttgta tatataggca aggggcaaga ccaagatttg ataggtttgg
     1621 atcttagggg caaaattgca gtaatggata gaatttatac aaaggattta aaaaatgctt
     1681 ttaaaaaagc tatggataag ggtgcacgcg ccattatggt tgtaaatact gtaaattact
     1741 acaatagaga taattggaca gagcttccag ctatgggata tgaagcggat gaaggtacta
     1801 aaagtcaagt gttttcaatt tcaggagatg atggtgtaaa gctatggaac atgattaatc
     1861 ctgataaaaa aactgaagtc aaaagaaata ataaagaaga ttttaaagat aaattggagc
     1921 aatactatcc aattgatatg gaaagtttta attccaacaa accgaatgta ggtgacgaaa
     1981 aagagattga ctttaagttt gcacctgaca cagacaaaga actctataaa gaagatatca
     2041 tcgttccagc aggatctaca tcttgggggc caagaataga tttactttta aaacccgatg
     2101 tttcagcacc tggtaaaaat attaaatcca cgcttaatgt tattaatggc aaatcaactt
     2161 atggctatat gtcaggaact agtatggcga ctccaatcgt ggcagcttct actgttttga
     2221 ttagaccgaa attaaaggaa atgcttgaaa gacctgtatt gaaaaatctt aagggagatg
     2281 acaaaataga tcttacaagt cttacaaaaa ttgctctaca aaatactgcg cgacctatga
     2341 tggatgcaac ttcttggaaa gaaaaaagtc aatactttgc atcacctaga caacagggag
     2401 caggcctaat taatgtggcc aatgctttga gaaatgaagt tgtagcaact ttcaaaaaca
     2461 cggattctaa aggtttggta aactcatatg gttccatttc tcttaaagaa ataaaaggtg
     2521 ataaaaaata ctttacaatc aagcttcaca atacatcaaa cagacctttg acttttaaag
     2581 tttcagcatc agcgataact acagattctt taactgacag attaaaactt gatgaaacat
     2641 ataaagatga aaaatctcca gatggtaagc aaattgttcc agaaattcac ccagaaaaag
     2701 tcaaaggagc aaatatcaca tttgagcatg atactttcac tataggcgca aattctagct
     2761 ttgatttgaa tgcggttata aatgttggag aggccaaaaa caaaaataaa tttgtagaat
     2821 catttattca ttttgagtca gtggaagaaa tggaagctct aaactccaac gggaagaaaa
     2881 taaacttcca accttctttg tcgatgcctc taatgggatt tgctgggaat tggaaccacg
     2941 aaccaatcct tgataaatgg gcttgggaag aagggtcaag atcaaaaaca ctgggaggtt
     3001 atgatgatga tggtaaaccg aaaattccag gaaccttaaa taagggaatt ggtggagaac
     3061 atggtataga taaatttaat ccagcaggag ttatacaaaa tagaaaagat aaaaatacaa
     3121 catccctgga tcaaaatcca gaattatttg ctttcaataa ccaagggatc aacgctccat
     3181 catcaagtgg ttctaagatt gctaacattt atcctttaga ttcaaatgga aatcctcaag
     3241 atgctcaact tgaaagagga ttaacacctt ctccacttgt attaagaagt gcagaagaag
     3301 gattgatttc aatagtaaat acaaataaag agggagaaaa tcaaagagac ttaaaagtca
     3361 tttcgagaga acactttatt agaggaattt taaattctaa aagcaatgat gcaaagggaa
     3421 tcaaatcatc taaactaaaa gtttggggtg acttgaagtg ggatggactc atctataatc
     3481 ctagaggtag agaagaaaat gcaccagaaa gtaaggataa tcaagatcct gctactaaga
     3541 taagaggtca atttgaaccg attgcggaag gtcaatattt ctataaattt aaatatagat
     3601 taactaaaga ttacccatgg caggtttcct atattcctgt aaaaattgat aacaccgccc
     3661 ctaagattgt ttcggttgat ttttcaaatc ctgaaaaaat taagttgatt acaaaggata
     3721 cttatcataa ggtaaaagat cagtataaga atgaaacgct atttgcgaga gaccaaaaag
     3781 aacatcctga aaaatttgac gagattgcga acgaagtttg gtatgctggc gccgctcttg
     3841 ttaatgaaga tggagaggtt gaaaaaaatc ttgaagtaac ttacgcaggt gagggtcaag
     3901 gaagaaatag aaaacttgac aaagacggaa ataccattta tgaaattaaa ggtgcgggag
     3961 atttaagggg aaaaatcatt gaagtcattg cattagatgg ttctagcaat ttcacaaaga
     4021 ttcatagaat taaatttgct aatcaggctg atgaaaaggg gatgatttcc tattatctag
     4081 tagatcctga tcaagattca tctaaatatc aaaagcttgg cgagattgca gaatctaaat
     4141 ttaaaaattt aggaaatgga aaagagggta gtctaaaaaa agatacaact ggggtagaac
     4201 atcatcatca agaaaatgaa gagtctatta aagaaaaatc tagttttact attgatagaa
     4261 atatttcaac aattagagac tttgaaaata aagacttaaa gaaactcatt aaaaagaaat
     4321 ttagagaagt tgatgatttt acaagtgaaa ctggtaagag aatagaggaa tacgattata
     4381 aatacgatga taagggaaat attattgctt atgacgatgg tagtgcctta caatatgaaa
     4441 ctgaaaaact tgacgaaata aaatcaaaaa tttatggtgt tctaagccca tctaaagatg
     4501 gacactttga aattcttgga aagataagca atgtttctaa aaatgccaag gtatattatg
     4561 gaaatagcta taaatcgata gaaatcaaag cgactaagta tgattcacat tcaaaaacga
     4621 tgatatttga tttatacgct aatattaatg atattgtaga tggattagct tttgctggag
     4681 atatgagatt atttgttaaa gatgatgatc gaataaaagc tgaaactaag attagaatgc
     4741 ctgaaaaaaa taaggaaact aaagcagaat atccctatgt atcaagttat gggaatgtaa
     4801 tcgaattagg agaaggagat ctttcaaaga acaaaccaga caatttaact aaaatggaat
     4861 ctggtaaaat ctattctgat tcagaaaaac aacaatatct gttaaaggat aacatcattc
     4921 taagaaaagg ctatgcacta aaagtgacta cctataatcc tggaaaaacg gatatgttag
     4981 aaggaaatgg agtctatagc aaggaagata tagcaaaaat acaaaaggcc aatcctaatc
     5041 taagagtcct ttcagaaaca acaatttatg ctgatagtag aaatgttgaa gatggaagaa
     5101 gtacccaagc tgtattaatg tcggctttgg acggctttaa cattataagg tatcaagtgt
     5161 ttacatttaa aatgaacgat aaaggggaag ctatcgataa agacggaaat cttgtgacag
     5221 attcttctaa acttgtatta tttggtaagg atgataaaga atacactgga gaggataagt
     5281 ccaatgtaga agctataaaa gaagatggtt ccatgttatt tattgatacc aaaccagtaa
     5341 acctttcaat ggataagaac tactttaatc catctaaatc taataaaatt tatgtacgaa
     5401 atccagaatt ttatttaaga ggtaagattt ctgataaggg tggttttaac tgggaattga
     5461 gagttaatga atcggttgta gataattatt taatctacgg agatttacac attgataaca
     5521 ctagagattt taatattaag ttgaatgtta aagacggtga catcatggac tggggaatga
     5581 aagactataa agcaaacgga tttccagata aggtaacaga tatggatgga aatgtttatc
     5641 ttcaaactgg ctatagcgat ttgaatgcta aagcagttgg agtccactat cagtttttat
     5701 atgataatgt taaacccgaa gtaaacattg atcctaaggg aaatactagt atcgaatatg
     5761 ctgatggaaa atctgtagtc tttaacatca atgataaaag aaataatgga ttcgatggtg
     5821 agattcaaga acaacatatt tatataaatg gaaaagaata tacatcgttt gatgatatta
     5881 aacaaataac agacaagaca ctaaacatta agattgttgt aaaagatttt gcaagaaata
     5941 caaccgtaaa agaattcatt ttaaataaag atacgggaga ggtcagtgaa ttaaaacctc
     6001 atagggtaac tgtgaccatt caaaatggaa aagaaatgag ttcaacgata gtgtcggaag
     6061 aagattttat tttacctgtt tataagggtg aattagaaaa aggataccaa tttgatggtt
     6121 gggaaatttc tggtttcgaa ggtaaaaaag acgctggcta tgttattaat ctatcaaaag
     6181 atacctttat aaaacctgta ttcaagaaaa tagaggagaa aaaggaggaa gaaaataaac
     6241 ctacttttga tgtatcgaaa aagaaagata acccacaagt aaaccatagt caattaaatg
     6301 aaagtcacag aaaagaggat ttacaaagag aagatcattc acaaaaatct gattcaacta
     6361 aggatgttac agctacagtt cttgataaaa acaatatcag tagtaaatca actactaaca
     6421 atcttaataa gttgccaaaa actggaacag caagcggagc ccagacacta ttagctgccg
     6481 gaataatgtt tatagtagga atttttcttg gattgaagaa aaaaaatcaa gattaagata
     6541 aaagctatag aaaaaaatgg tttatgtact gagattagat agtgaggtga tgacatagtt
     6601 ttgtgaaaac agccatttat aactcaatta tttagtttac ttcactattg atactatttg
     6661 gagttattaa tggacttagt ttagataact aatgaattga ttgaaagggt tagtattgac
     6721 aatattggtc atattgatta gaaaatagag tctatcaaaa tttaaaggct aatagaggtg
     6781 atgagacaat ttcggctctt tgtcaactgt agtgggttga agtcagctaa gctcgagaaa
     6841 ggacaaattt
//
LOCUS       DAVKUR010000076         6847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKUR010000076 DAVKUR010000000
VERSION     DAVKUR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.076"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..752)
                     /locus_tag="VW749_001942"
     CDS             complement(<1..752)
                     /locus_tag="VW749_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0175925.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNTPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQI
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHAQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(749..2074)
                     /locus_tag="VW749_001943"
     CDS             complement(749..2074)
                     /locus_tag="VW749_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0175926.1"
                     /translation="MDFFLLVDLILYFLIISHSYRLICKDQINRKELFFFGAYTLLTE
                     IVLDFPFYLLYLDGLGIATFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYYGLFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKRKFE"
     gene            complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VW749_001944"
     CDS             complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VW749_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0175927.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFNFFR
                     RR"
     gene            complement(2392..2465)
                     /locus_tag="VW749_001945"
     tRNA            complement(2392..2465)
                     /locus_tag="VW749_001945"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2429..2431),aa:Arg,seq:tct)
     gene            complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VW749_001946"
     CDS             complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VW749_001946"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0175928.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3171..4352
                     /locus_tag="VW749_001947"
     CDS             3171..4352
                     /locus_tag="VW749_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0175929.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            4410..5168
                     /locus_tag="VW749_001948"
     CDS             4410..5168
                     /locus_tag="VW749_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0175930.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            5381..6742
                     /gene="dnaA"
                     /locus_tag="VW749_001949"
     CDS             5381..6742
                     /gene="dnaA"
                     /locus_tag="VW749_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0175931.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT         2374 a         1221 c         1087 g         2165 t
ORIGIN      
        1 cacttttgag attttttctc taaaatatct tttaattttc taatttttaa tcttgaaata
       61 ggacaacgat ggtcttcata gaaaacaatt tctaagtttt ttcgatcaat ttctctgata
      121 ttgcctatat ttaccaaaaa tgacttgtga ggagaataaa atcgctgagc atgtttgtcc
      181 ttttcctgaa tatctgtcat ggtaccataa aactcttttg caaaattctt accaataatg
      241 cgcaatttat gagagactcc tgtcgtttca atatacaaaa tatcatggta aggaattttt
      301 aaatcatttc ccttgtaatt gtagtcgaaa taatctacaa catcttcatt ttcaagtaac
      361 atactcttcg tgtagaagat attttgctca attcgcttct taaacatctc atcgttgata
      421 tccttatcaa caaaatctag ggctgatatc tggtatttat aggtcagagt cgcaaactct
      481 gatcgactgg tgataaagac gataatagcg taaggattgt aatgacgaat gagttgagca
      541 acttcaaatc cctttttctc aattccatga atatcgatat ctaggaaata aagttgattt
      601 acttcatcat tttcaatgta ttcttcaaat tcacggactt ttcccgttgt cttgtatgat
      661 attggagtat tcgattcttt cgaaatttca tccaatattc tctctagtct cacttgatgt
      721 tcaataacat cttctaaaat taaaactttc attcaaattt cctcttaaat ctaatgattt
      781 gtctaaatgt actgccttcc atctctgttt ctaaaataat gttgttgtac ttatctagta
      841 gttctttcac attatttaat ccgactccgc gatttcttcc cttagtggag aatcctaagg
      901 caaatagatc tcctgaagga gtcatcgtca ttttacatga attctgaatc acaataactg
      961 tttcagtttc catcttaata actgctactt ccatctgctt tttatagcta tcagccgatc
     1021 cttcgacagc attgttcaat aaaacgctca tgatacgcac taaatccaat agttcaattg
     1081 gaagcttggt aatcgtatct tttacttcca gtgtaaactc tacaccatta tttcgagcat
     1141 agacaattga ctgagcaacc aaacttcgta aagctgaatc ttctatgttg ttcaaatcaa
     1201 agtaagtgta cttatctgaa cgtagtttat gatttgcttt gaccaaaact tcattgtaaa
     1261 ctctgtcaat ttcctgtaaa ttaccactgt caattgccat ctgcatgctg acaagcattc
     1321 cagcataatc atgtcgaaaa ccacggattt cattatacag accgacaatt tcatctgtgt
     1381 aattctgtaa atgtttctgt tcaaatttct tctgcttcaa agcaatctct ttctccattt
     1441 gaactttatg agaattcatt gcaaagaagg tcaaaaggag agagataaag acaatagatg
     1501 acaaaatact tccaaaacta ttcaaatgtt taatcgtact taccatatct gaaacgaaag
     1561 atacaatatg tagcaatagt aaagcaaaaa atactttttt caagaaagga taaaggtagt
     1621 ccttgtcaaa ataggctagt tccaaatgga aataataaat gatttttaat gtaacaaaat
     1681 aggtcaacac cgtcacaacg aaaaagaata ggccataata ctgtaaaaca aaattgtctc
     1741 ctgttataga agagaaagtt acggacagaa agttatgagt gctctcatat aaaagagata
     1801 gtagtaaact tagaaatagt cctctatccc tctcatactg tttcatccat cgaaaatagg
     1861 aatataggcc caaaggaaat aaaaatgttg caatccctaa cccatctaaa tatagaagat
     1921 agaagggaaa atcaagtact atttctgtta gtaatgtata agcaccaaaa aagaataatt
     1981 cttttctatt tatttgatct ttacaaatta aacggtaact atgactaata attaaaaaat
     2041 ataatatcaa atctactaat aagaaaaaat ccattctgct actcctttat cttcttctaa
     2101 agaaattaaa gaaattaaag atattaaagg acttttcatt cattttcctc atctccccac
     2161 cttgaatatt ttgcaagtct ttttccttca aagctacaaa ctgttccaat ttaactgtgt
     2221 ttttcataat aaaatctcct aaaatgtttt ttcttgtaag ctaacttaca aaaaccatta
     2281 tacaaaatgg aatttcgttt tagataaaat tctctcaact gtcatttttt tctcccaaag
     2341 tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt tgctattata ttgatcccag
     2401 caggattcga acctgcgacc gttcgcttag aaggcgaatg ctctatccag ctgagctatg
     2461 agacctaaca caattattct accaaaaatt caattaaaag tcaattttct atttatggta
     2521 ggggaatccc tgctgaatcg taaaagcgcg atagatttgt tcaacaagaa ctagtctcat
     2581 taactgatga ggcaaggtta ggcgaccaaa actgacagaa agattggctc tattttttac
     2641 agatgatgat aatcctaaac ttcccccaat aataaaagta agagtagaaa atccttttat
     2701 agaagtttct tctaactgct tactaaattc ttctgagaag aaagttttcc cttcaatggc
     2761 taacacaata acgaaatcac ggtcagcaat ttttgataaa attctctgac cttctatttc
     2821 taaaatcttt tgattttctg attcactggc cttatctggt gttttttcat ctgataactc
     2881 aatcatttca aacttagcaa atctagaaat tcgttttgaa tactctgcga taccatcttt
     2941 taaatacttt tctttcagtt tcccaactgt tacaacttta attttcatga ctctattcta
     3001 acatattctc tattttttca catcttattc acaaaataaa aaatagattt caattaagaa
     3061 aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa cttttgtgtt taagttataa
     3121 ttaagctagt cagtttatac tttcagtaat tcaaacatat ggaggcaaat atgaaacatc
     3181 taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt tatcgtcatt agctttttta
     3241 gtggagcctt gggtagtttt tcaataactc aactaactca aaaaagtagt gtaaacaact
     3301 ctaacaacaa tagtactatt acacaaactg cctataagaa cgaaaattca acaacacagg
     3361 ctgttaacaa agtaaaagat gctgttgttt ctgttattac ttattcggca aacagacaaa
     3421 atagcgtatt tggcaatgat gatactgaca cagattctca gcgaatctct agtgaaggat
     3481 ctggagttat ttataaaaag aatgataaag aagcttacat cgtcaccaac aatcacgtta
     3541 taaatggcgc cagcaaagta gatattcgat tgtcagatgg gactaaagta cctggagaaa
     3601 ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa aatctcttca gaaaaagtga
     3661 caacagtagc tgagtttggt gattctagta agttaactgt aggagaaact gctattgcca
     3721 tcggtagccc gttaggttct gaatatgcaa atactgtcac tcaaggtatc gtatccagtc
     3781 tcaatagaaa tgtatcctta agatcggaag atggacaagc tatttctaca aaagccatcc
     3841 aaactgatac tgctattaac ccaggtaact ctggcggccc actgatcaat attcaagggc
     3901 aggttatcgg aattacctca agtaaaattg ctacaaatgg aggaacatct gtagaaggtc
     3961 ttggtttcgc aattcctgca aatgatgcta tcaatattat tgaacagtta gaaaaaaacg
     4021 gaaaagtgac gcgtccagct ttgggaatcc agatggttaa tttatctaat gtgagtacaa
     4081 gcgacatcag aagactcaat attccaagta atgttacatc tggtgtagtt gttcgttcgg
     4141 tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata cgatgtaatt acaaaagtag
     4201 atgacaaaga gattgcttca tcaacagact tacaaagtgc tctttacaac cattctatcg
     4261 gagacaccat taagataacc tactatcgta acgggaaaga agaaactacc tctatcaaac
     4321 ttaacaagag ttcaggtgat ttagaatctt aattgacatc tatgtaaaga aagctttaca
     4381 taagagaaaa gatgtgttag tgtagaatca tggaaaaatt tgaaatgatt tctatcacag
     4441 atatacaaaa aaatccctat caaccccgaa aagaatttga tagagaaaag ctagatgaac
     4501 tagcacagtc tatcaaagaa aatggggtca ttcaaccgat tattgttcgt caatctcctg
     4561 ttattggtta tgaaatcctt gcaggagaga gacgctatcg ggcttcactt ttagctggtc
     4621 tacggtctat cccagctgtt gttaaacaga tttcagacca agagatgatg gtccagtcca
     4681 ttattgaaaa tttacagaga gaaaatttaa acccaataga agaagcacgc gcctatgaat
     4741 ctctcgtaga gaaaggattc acccatgctg aaattgcaga taagatgggc aagtctcgtc
     4801 catatatcag caactccatt cgtttacttt ccttgccaga acagattctc tcagaagtag
     4861 aaaatggcaa actatcacaa gcccatgcgc gttccctagt tgggttaaat aaggaacaac
     4921 aagactattt ctttcaacgg attatagaag aagatatttc tgtaaggaag ttagaagctc
     4981 ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa ttatttcata caaaatgaag
     5041 aaaaacagtt aagaaaacta ctcggattag atgtagaaat taaactatct aaaaaagaca
     5101 gtggaaaaat cattatttat ttttcaaatc aagaagaata tagtagaatt atcaacagcc
     5161 tgaaataagg ctgttctttt atttttttat ctcacaaggt tatccactat gtttttcgat
     5221 aaaaagctta ataaatcaat aatttcttct tttatcccca acctgtggat aaagtttagt
     5281 aacattgtgg attatttttc acagcttgtg gaaaattctt gctatctatg gtaaaatatc
     5341 tctagtatta aacttttaaa tagtaaagga ggaaaaagga ttgaaagaaa aacaattttg
     5401 gaatcgtata ttagaatttg cacaagaaag actgactcga tccatgtatg atttctatgc
     5461 tattcaagct gaactcatca aggtagagga aaatgttgcc actatatttc tacctcgctc
     5521 tgaaatggaa atggtctggg aaaaacaact aaaagatatt attgtagtag ctggttttga
     5581 aatttatgac gctgaaataa ctccccacta tattttcacc aaacctcaag atacgactag
     5641 ctcacaagtt gaagaagcta caaatttaac tctttatgac tatagtccaa agttagtatc
     5701 tattccttat tcagatacgg gattaaaaga aaagtatacc tttgataact ttattcaagg
     5761 ggatggaaat gtttgggctg tgtcagccgc tttagctgtc tctgaagatt tggctctgac
     5821 ctataaccct ctttttatct atggaggacc aggccttggt aagactcact tattaaacgc
     5881 tattggaaat gaaattctaa aaaatattcc taatgcgcgt gttaaatata tccctgccga
     5941 aagctttatt aatgactttc ttgatcacct aagacttggg gaaatggaaa agtttaaaaa
     6001 gacctatcgt agtcttgatc ttttgttaat cgatgatatc cagtcactca gcggaaaaaa
     6061 agtcgcaact caggaagaat ttttcaatac ctttaacgcc cttcatgaca agcaaaaaca
     6121 gattgtccta acgagtgatc gtagtccaaa acatctagaa gggctcgagg agaggcttgt
     6181 cacgcgtttt agttggggat tgacacaaac tatcacaccc cctgactttg aaacacgtat
     6241 tgccatttta caaagtaaaa cggaacattt aggctacaat ttccaaagtg atactctaga
     6301 atacctagct gggcaatttg attcaaatgt tcgagatctt gagggagcca tcaacgacat
     6361 cactttaatt gccagagtaa aaaaaatcaa ggatatcact attgatattg ctgcagaagc
     6421 cattagagcc cgcaaacaag atgttagcca aatgctcgtc atcccaattg ataaaatcca
     6481 aactgaagtt ggtaactttt atggtgttag tatcaaagaa atgaagggaa gtagacgcct
     6541 tcaaaatatt gttttggccc gtcaagtagc catgtattta tctagagaac taacagataa
     6601 tagtcttcca aaaattggga aggaatttgg gggaaaagat cataccacag tcattcatgc
     6661 ccatgccaaa ataaaatctt tgattgatca agacgataat ttacgtttag aaattgaatc
     6721 aatcaaaaag aaaatcaaat aatttgtgga taacttttag ttttttatct tttttatcca
     6781 cattttttaa acaagctaaa aaacttgata ggacttgttt aaaggctgtt ttccacagat
     6841 ttcacag
//
LOCUS       DAVKUR010000077         6847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKUR010000077 DAVKUR010000000
VERSION     DAVKUR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.077"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(104..379)
                     /locus_tag="VW749_001950"
     CDS             complement(104..379)
                     /locus_tag="VW749_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0175932.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(486..1325)
                     /locus_tag="VW749_001951"
     CDS             complement(486..1325)
                     /locus_tag="VW749_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0175933.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1467..2315
                     /locus_tag="VW749_001952"
     CDS             1467..2315
                     /locus_tag="VW749_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0175934.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2408..3325)
                     /locus_tag="VW749_001953"
     CDS             complement(2408..3325)
                     /locus_tag="VW749_001953"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0175935.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3671..3879
                     /locus_tag="VW749_001954"
                     /pseudo
     CDS             3671..3879
                     /locus_tag="VW749_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4189..4482)
                     /gene="rpmA"
                     /locus_tag="VW749_001955"
     CDS             complement(4189..4482)
                     /gene="rpmA"
                     /locus_tag="VW749_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0175936.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4499..4843)
                     /locus_tag="VW749_001956"
     CDS             complement(4499..4843)
                     /locus_tag="VW749_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0175937.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4859..5173)
                     /gene="rplU"
                     /locus_tag="VW749_001957"
     CDS             complement(4859..5173)
                     /gene="rplU"
                     /locus_tag="VW749_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0175938.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5209..5296)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5361..6059)
                     /locus_tag="VW749_001958"
     CDS             complement(5361..6059)
                     /locus_tag="VW749_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0175939.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6461..6760
                     /locus_tag="VW749_001959"
     CDS             6461..6760
                     /locus_tag="VW749_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0175940.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2145 a         1386 c         1143 g         2173 t
ORIGIN      
        1 cggaacattc aactttttaa ctctatttat tactagattt cataattaaa aagcctactg
       61 accaagctag aaagcttgat acaataggct ttttaaagac tgattattta acagcgtctt
      121 taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc atttctttac
      181 cagtttgtgg gttgcgacct ttacgttctg cgcgctcacg aacttcaaag ttaccaaaac
      241 cgatcaactg aactttttca ccagctgcaa gatagtcagc tactgctgca aatacagctt
      301 caactgctgc tgctgagtct ttcttagtta attctgtagc ttctgctact ttagcgatca
      361 aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta acaaatataa
      421 tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc attttattta
      481 tttttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt gtgagtttga
      541 ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg taagctttct
      601 ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc tgctacagca
      661 cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt agttccacga
      721 cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacaacacg gatattgaga
      781 agagagctca acaagccagt tacacggcta attcgtccac ctttgacaag attttccaaa
      841 gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg agataaaatt
      901 gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg gaatttcagg
      961 gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag gctagcacct
     1021 tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc aagaatctgg
     1081 ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg tggctgactt
     1141 gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc ttctttcaaa
     1201 tccgcatcag aataaacaac attatcaatc attacagata atggaacaat tgtaatatct
     1261 aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat cttaattttt
     1321 gtcatagtat caatctttct attttaggat tcagattggt ttccttactt ctaattatat
     1381 caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa tttgatataa
     1441 tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt tttaccattt
     1501 tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc catcatctct
     1561 ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa atccctgttt
     1621 ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag atctttggag
     1681 ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg ttagcttttt
     1741 ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca gcccttatag
     1801 cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt acaactggcg
     1861 gaactgatat tctagctcgt attctcaaca aatacactca tatatccata ggaaaactgc
     1921 tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag gatttgagat
     1981 tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat ttgattggtg
     2041 aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac caacttgcta
     2101 aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttctggtcaa ggctactata
     2161 gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt gtgaaaacga
     2221 aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa gcccatgaaa
     2281 tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg tgacctcaaa
     2341 agttagacta aatcatctat cttttgggtt acagacaacc tcttttttgt tttatttact
     2401 caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga tccactaatt
     2461 ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa accatgacgg
     2521 tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt gcttcttctc
     2581 catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt ctttgaatct
     2641 caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa agcactaaat
     2701 tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc atacctcttg
     2761 atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct aaaatagctt
     2821 gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga acaatgataa
     2881 cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa ccaaatgtat
     2941 aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt gcaaagaatt
     3001 cttgtgcagt aagactagcg aattgactac taaaatcaag gagatataat tcttctacac
     3061 cttcgcgctt taattttctt tcacgttcag cagggttcaa aatatgcaaa aacaaatctg
     3121 gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg acgataggta
     3181 ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc cccttatgta
     3241 tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata tctttttggt
     3301 tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc tatttctgga
     3361 acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca aaaagcactt
     3421 tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact tgtaggacat
     3481 cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg tcatactatg
     3541 ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta attggtgccg
     3601 aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa aatgagacaa
     3661 cttgggcaag atgtttgaag aatttcctaa actcccatct agtgtgcttc agactaggct
     3721 atttttctct ccatctgtta gcttggattc tcagaccgtt tcagctaaag aatatctttt
     3781 cccttatcag aaggaacggc tcaagccatt cagacaagtg aagggacgac aagccaatat
     3841 ttgaaaccag atagcagttc ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg
     3901 aaactcatat caatttttaa cagtgttcta ttccagattc atactcaatg aaaattaaag
     3961 tgcaaactag gaagttagcc gcaggctgta cttgagtacg gcaaggtgaa attgacgtgg
     4021 tttgaatttg attttcgaag agtatcaatc cactatacat attaaaaagt atgggtatca
     4081 aaataaaaaa caggctctcc gaaaactcgg aaagccttat tttaagctgt ttctagcttc
     4141 ctcaccttta catttcaagg ttcgggataa aaggttcaat ggaccttttt atttagcgat
     4201 tgggtaaaca gaaacttgtt ttttatcgcg tcctttacgt tcaaagcgta ctacgccttc
     4261 aactttagcg aacaaagtat cgtctccacc acgaccaacg tttacacctg gatagatgtg
     4321 tgtaccacgt tgacggtaaa ggattgatcc acctgttaca gtttgtccgt cagctgcttt
     4381 agctccaaga cgttttgctt gtgaatcacg tccgtttgat gtagaacctc cacctttttt
     4441 gtgggcgaaa agttgcaagt tgttaagagt catttttaac ataatgtttt cctccgtgtt
     4501 agttttctgt gataactctg gtttggacga actcagaata gttctccgat aagtttgcca
     4561 tacctaagaa aaatgattca aagaataact gggtcatttc tctctggtgt gaaggaagat
     4621 cttttggtat ttcaaccatc agatagccac cttcatcttc gtttaattct aggattggtt
     4681 catagcctgc aaatttctca atagaattga taaagttaat ggcaagcgta gaaaccgatg
     4741 cacacacgac atctaagccg tattcgccac tctcggcgtg tccagtaatt tccgcactcc
     4801 tcagctcgcc atcttcggct ctctcaaaga ctgcctgtat catgtgttct ccttaaaatt
     4861 aagcgttgat tgcgttgatg acaacttttg tatatggttg acggtgacct tgtttacggt
     4921 ggctaccttt tttaggtttg tacttgtaag taaccacttt cttttgtttt ccttgttttt
     4981 caacagttcc aactacagta gctccagcaa caagtggagt tccgacaaca gtgttttcac
     5041 caccaacaag aacaacttcg ttaaaagtaa cttcttgacc agcttcaacg ttcaattttt
     5101 caacgtaaac tgcttgacca acttcaactt taacttgttt tccgccagtt ttgataattg
     5161 cgtatgtgct cattatgcac ctcctatgat ttttatgggt ttccccgatt ttttgtgaag
     5221 actcgcctag catcgtggga cgaaccactt aaacttgaat aatcaagcaa cgatgttcgt
     5281 gcggttgcac aggatcgtgc atagtcaact cttcaagtat agcatatctc ctattttctt
     5341 acaagtaata acacctaaaa tcaagctttt tcttttactt ttttctgcca agaggcaaaa
     5401 agcatgctga ggtaaaaaac gctcatcata ataggaacac caagaatggt cttttcatga
     5461 tagaaaatcg tcaaataggc tgaaaagaca acgccaagga caaaactact aagcaggcta
     5521 acaaatatga atccttcacg caaaaaagga gtgtgcttgg ttcggaaata atctccaaaa
     5581 gccagcatgg tccgtttgat attccctgtc ataaaagcgt tattataggc aatacccgac
     5641 acttctccaa aagcagttgt caccagtccc atacagaagg ccaagggcgg cactagatag
     5701 atattatcca cagtttgcgg cacaaaagca ataatgattg ataagattgc caagggaatc
     5761 aaggacagaa taggtttttt cacaattctc aatttttcct tataaatcgt taataaaaag
     5821 actcccatca taaacgctag caaggtgaga accttgtccc taacatccga aacattattt
     5881 ttaattaatt ctactgaaag aaagacaaca tttccagttt gtccagctac aagggtattc
     5941 ccgcgaacaa taaaagtgta agcatccaca tatccagcac aaaacgtcaa aaaaagtgct
     6001 aaccttttag actgacgtga tatttttctt ataggtaata acctcatttt acctcccatt
     6061 gtattttctc ttagaaatat tgtaccattt tctttctaaa aaatcgtagg ctaccattta
     6121 gattttacta ttagcataaa aataataata gacaactatt tatccaaaaa tagatagatg
     6181 taacatgttt gcaaacaaag catacgaacc tttagtaaaa tcatttccat gaaactagaa
     6241 tagagccctc ttagcaaaaa tcattatttt aatttatttc taatcactcc ttgacataaa
     6301 taactctcac caataaaaga ctatgtctta aaaaaatggt ataataaaat caatacttgg
     6361 gcttgatggc tatgctacta ataacaatta ggagagaaaa tcaggcactt gttaacaaca
     6421 aggattatcc ccttgagatg aaaggaactt tagaaatctt atgatgaaca tgcaaaacat
     6481 gatgcgtcaa gcacaaaaac ttcaaaaaca aatggaacaa agccaagctg aacttgctgc
     6541 tatgcaattt gttggcaaat ctgctcaaga tcttgtccaa gcgaccttaa ctggcgataa
     6601 gaaagttgtc agcattgatt tcaatccagc tgtcgttgac ccagaggacc ttgagactct
     6661 ttctgatatg accgttcaag ccatcaactc tgctcttgaa caaatcgatg aaactaccaa
     6721 gaaaaaactg ggtgctttcg ctgggaaatt acctttctaa aaacaaggag ctagaacaat
     6781 gcttgtcgat aacaaaggct aagaaaggtg caaaaatgac tctataatat ttgtagtggg
     6841 taaatcc
//
LOCUS       DAVKUR010000078         6655 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKUR010000078 DAVKUR010000000
VERSION     DAVKUR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.078"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(73..165)
                     /locus_tag="VW749_001960"
                     /pseudo
     CDS             complement(73..165)
                     /locus_tag="VW749_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(201..484)
                     /locus_tag="VW749_001961"
                     /pseudo
     CDS             complement(201..484)
                     /locus_tag="VW749_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(474..614)
                     /locus_tag="VW749_001962"
     CDS             complement(474..614)
                     /locus_tag="VW749_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0175941.1"
                     /translation="MVSCHSSLRSYIAEPILKQAGFTVQNLDGAYSLYKMVNPEGVEY
                     GN"
     gene            706..1470
                     /locus_tag="VW749_001963"
     CDS             706..1470
                     /locus_tag="VW749_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0175942.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2035..3414
                     /locus_tag="VW749_001964"
     CDS             2035..3414
                     /locus_tag="VW749_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0175943.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3428..4093
                     /locus_tag="VW749_001965"
     CDS             3428..4093
                     /locus_tag="VW749_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0175944.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4228..4302
                     /locus_tag="VW749_001966"
                     /pseudo
     CDS             4228..4302
                     /locus_tag="VW749_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4448..4987
                     /locus_tag="VW749_001967"
     CDS             4448..4987
                     /locus_tag="VW749_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0175945.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            5054..5464
                     /locus_tag="VW749_001968"
     CDS             5054..5464
                     /locus_tag="VW749_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0175946.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5580..>6655
                     /gene="pavB"
                     /locus_tag="VW749_001969"
     CDS             5580..>6655
                     /gene="pavB"
                     /locus_tag="VW749_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0175947.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKA"
BASE COUNT         1813 a         1283 c         1525 g         2034 t
ORIGIN      
        1 aaaacagtgt tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga
       61 gctgacttcg tcagttccat ccacaacctt aaaacagtgt tttgagcagc ctgcggctaa
      121 cttcctagtt tgcactttaa ttttcattga gtattacttc atcttctcat gaaattgagt
      181 ttttgcccag ctcctcttga ttattctact tgaccgggcc aagcattcat accaccttct
      241 acgttggtaa cggtgaggcc ttgggagctg agaaattggc aggtagatgc agagcggact
      301 cctccgtgac aaatgacata gtattcatgg tcaggtttga gttctttgta gccttgctct
      361 aaggtattta tggaagattt ttgggtcctg cttggaattc atgtgcttca cggacatcga
      421 taagttccag attttcattt tgatattttc tataaaagtc agccatgctg atactagttt
      481 ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc gtcaaggttt
      541 tggacggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg caaactactg
      601 tggcaactga cgatgtaggc ttgtttttct cctcagttca tcagcttcct ccttgacact
      661 cggtcagatt ttgatacaat agtacaaaat tagaggaggt gggctatgat tcagaaacat
      721 gcgattccca ttttagagtt tgatgataat cctcaggcgg ttatcatgcc caatcacgag
      781 gggttggatt tgcagttgcc aaagaagtgt gtctatgctt ttttaggtga ggagattgac
      841 cgctatgcga gggaagtagg ggcgaactgt gttggcgaat tcgtttctgc taccaagacc
      901 tatccagtct atgtcatcaa ctacaagggt gaggaggtct gtctggctca ggctcctgtt
      961 ggctccgctc cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt
     1021 atctctactg ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct
     1081 gttcgcgctc tgcgagatga aggagccagt taccactatg tggcaccttc tcgttatatg
     1141 gaaatgcagc cagaggctat tgctgccatt gagcgagttt tggatgatag agggattcct
     1201 tatgaagaag tcatgacctg gtccacagat ggtttttacc gagaaacggc tgaaaaggtg
     1261 gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca
     1321 gtagctcaat tgcgtggagt tctctggggt gaattgttgt tcacagcaga ttctctagcg
     1381 gacttggacc agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcactagaa
     1441 ctgagtttag caagtgttca ccacctttag ttgtactggc aaaggatttg ttttatcata
     1501 aaatgtctag ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct
     1561 aggcatgttg aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg
     1621 aaaattttga tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc
     1681 ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg tatagatgtt actgacttcg
     1741 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaagc
     1801 gatgccttgg ttctcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata
     1861 gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag
     1921 tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtag
     1981 attttgcctt atcctatcta agtcatttcg aactttttat ggtacaatgg aaacatgtta
     2041 ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt
     2101 atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt
     2161 gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca
     2221 gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa
     2281 ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacctt tattggggtt
     2341 ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt
     2401 tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc
     2461 tttttggttg agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc
     2521 tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt
     2581 tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg
     2641 gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct
     2701 ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta
     2761 ttgactatag gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat
     2821 gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca
     2881 gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact
     2941 cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga
     3001 ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg
     3061 cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt
     3121 gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc
     3181 aaaggcaatc ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt
     3241 ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca
     3301 cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat
     3361 ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg
     3421 aaagagcatg tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt
     3481 cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg
     3541 catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga
     3601 attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa
     3661 tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat
     3721 tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt
     3781 tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag
     3841 tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc
     3901 ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt
     3961 gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt
     4021 gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc
     4081 attgaattcg taaagaggga tgacccctct tttttgatgc ctaagatggc aaatagagac
     4141 agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa
     4201 agaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct
     4261 acgggctgct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa
     4321 cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac ggcaaggcga
     4381 cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc ccctaaagga
     4441 gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag cctatcttca
     4501 ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga ttatcaatga
     4561 cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt atcctaatat
     4621 cgttagagcc atctatcagg aaaataaatg ccatggcggt gcggtcaatc gtggcttggc
     4681 agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg atcctcgtgc
     4741 ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag aggtggatgt
     4801 ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga gtatgagtta
     4861 cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa atttctccaa
     4921 aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca
     4981 gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca
     5041 gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga
     5101 ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa
     5161 tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa tgcgagaata
     5221 tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca accgatctgg
     5281 aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc agaaaaatcc
     5341 agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt
     5401 gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa
     5461 ttaatataag tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt
     5521 ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta
     5581 tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg
     5641 ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac
     5701 gtgccgatgt ggtcaatccg accccaggtc aagtcttacc tgaagagaca tcgggaacga
     5761 aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg
     5821 gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg
     5881 aaacaaactc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caaaaaaatc
     5941 cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat gggacacaag
     6001 caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag
     6061 acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt cctttcactg
     6121 ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc
     6181 tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg
     6241 ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg
     6301 gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc
     6361 aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta
     6421 atctagttgc tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaacag
     6481 ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca gcctacctag
     6541 aaaaagccaa gggtgaaggt ccattcacag caggtgtcaa ccatgtgatt ccatacgaac
     6601 tcttcgcagg tgatggtatg ttgactcgtc tcttgctcaa ggcatctgac aaggc
//
LOCUS       DAVKUR010000079         6588 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKUR010000079 DAVKUR010000000
VERSION     DAVKUR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.079"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..458
                     /locus_tag="VW749_001970"
                     /pseudo
     CDS             1..458
                     /locus_tag="VW749_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            386..838
                     /locus_tag="VW749_001971"
     CDS             386..838
                     /locus_tag="VW749_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175948.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1657..2016
                     /locus_tag="VW749_001972"
     CDS             1657..2016
                     /locus_tag="VW749_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175949.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2026..2391
                     /locus_tag="VW749_001973"
     CDS             2026..2391
                     /locus_tag="VW749_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0175950.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2378..4228
                     /locus_tag="VW749_001974"
     CDS             2378..4228
                     /locus_tag="VW749_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0175951.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFTKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHSDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLINSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            4484..5916
                     /locus_tag="VW749_001975"
                     /pseudo
     CDS             4484..5916
                     /locus_tag="VW749_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(6154..6288)
                     /locus_tag="VW749_001976"
                     /pseudo
     CDS             complement(6154..6288)
                     /locus_tag="VW749_001976"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         2291 a         1049 c         1291 g         1957 t
ORIGIN      
        1 aatagttgta gtaactgatc ataatactac caaaggtatt aaaaagttac aaatggcagt
       61 ctcaatcata atgaaaaatt atccgattta tgatatacat cctcatattt tacatggagt
      121 agaaattagt gcagcagata aattgcatat tgtatgtata tatgattatg aacaagaatc
      181 atgggttaat caatggttaa gtgaaaatat tataagtgag aaagatggaa gttatcaaca
      241 ttcactgact ataatgaagg atttcaataa tcaaaaaata gttaactata ttgctcattt
      301 caatagttat gacattttga aaaaaggttc tcacttatca ggtgcatata aacgaaaaat
      361 tttttctaaa gaaaatacac gatttttgga gtttaatatt aactcgaaag aatcttcgca
      421 acaacttgat attctctata aagaagttgg tgtattaagt ttgggacaaa aagttgtagc
      481 catgcttgat tttttattag catatagtga ctattctaaa gacttcagac cattgattat
      541 tgatcagcct gaagacaatc tagacaatcg ttatatttac aggcatttag ttcagcagtt
      601 tagagatgtg aaagctcaac gtcaaattat tttagcaaca cataatgcta caattgtaac
      661 aaattctatg acagatcaag ttgttattat ggagtcagat ggagttaacg gatggattga
      721 atcacaggga tatgttagtg aaaaatatat aaaaaatcat atcatcaatc aattagaggg
      781 aggaaaagat tccttcaagc ataaaatgtc tatatatgag acggctttat cagagtagag
      841 tcagaaaaag taggttagaa atttagccta cttttttctt tgttcgacag gcatagtgta
      901 catctgaggt ccaagtcctc tgtggatatt tgctgcagat gaaaccaata gcgactccta
      961 agcctgaata tcgtgaggta ggggggatag gaaggaatta gcgaaatcaa ggttctacaa
     1021 acagaatcgt gacttgaagc catatatagc ggatgaggaa ctctaaaatc caaataggtg
     1081 tcgtaaccta tatacgtaaa ttacgagagt aaactaggaa agatgtacgg cttattccgt
     1141 gagcgtttag gacgtagtac aacgaatcat gggagtcagc tgaacacata gtattgaaga
     1201 aatttctgta atggaaatgg agcgaagaag tgaacaatta aatgaatacc tctctaatta
     1261 aatttgtcaa ttctaattcc tggtatgaaa agacagtgac ctaaaaatgt aaacgatggg
     1321 agctgatcat aaatatagga cggtacatgc agtggtgtta gagattagtc cctacttgat
     1381 ttgtgataac ttccccaact ttcttctgct atacttttct caacttttaa aaatccaact
     1441 aagaatttta cctgggagtt tgggggcgta gccaccaagt tatcttatgg ttagctgtca
     1501 aaactggaag gttttggtta gctggcgata tgattttttg ggtattgtga ccacaatgcc
     1561 tgagctcgca aagaccgaac aaggacttta agaaatttcc cgtatgacac acggggtcgg
     1621 ggtttacccg agaaaggatg aaagtgagga aaagagatgt ctgaacagta ccgtgacatt
     1681 cgaaaagagg taaatctaac cgcagatgag ctaaaacaga ttgaaaaaat gatggaggtt
     1741 gataattatc gtcacttttc accattcgtc agggataaaa ttttgatgac tgatgacaaa
     1801 cagttagctg ccaaagaatg gttttccctt tggcagtctc aaaagtttga acagatcagt
     1861 cgagatgtgc atttggtttt gattatcgca agagagaatc accaagtgac tcaagaacac
     1921 gtgtcaatct tattgacctg cgttcaagaa ttgattgcgg aagtcaatca agtacagtca
     1981 ctcagtcgtg ggtttcgtga aaaatacatg agataggagg ctactatggt ttatcgttat
     2041 cgtaccaatc tcaaaaaagt atttctaaca gattcagaat tacaccaatt gaatgaacgg
     2101 attgctaaga gcaattgtca aaatttttca gtctatgcca gaaaagtttt gcttaatccc
     2161 aatatgtcat ttgtcacgat taacacggat acttatgacc agttagtttt tgaattgaga
     2221 cggatcggaa ataacattaa tcaaattgcg cgtgctatca atcaaagccg tctgatttct
     2281 caggaacagt tacaagaatt gagtaaagga gtcggagagt tgatcaagga agtggacaaa
     2341 gaatttcaag tggaagtgaa aagattgaag gagtttcatg gtagtcacta agcattttgc
     2401 gacacacgga aaaaaatatc gtaggcgttt aattaagtat atcctcaatc ctgataaaac
     2461 ggacaatttg aaattagtat ctgattttgg tatgagcaat tacttagact ttcctagcta
     2521 tgaagaaatg gtagaaatgt acaatgtcaa ctttaccaat aatgacaagt tgtacgaata
     2581 cagaaatgac cgacaagaaa aacaccaaca aaatattcat gcccatcacc tcattcaatc
     2641 attttctcct gaagataatc tgacacctga agaaattaac cgcattggtt atgagaccat
     2701 tatggaatta acaggaggcc gttttcgttt catcgtagcg actcatacag acaaagatca
     2761 tattcataat cacatcttaa tcaacgccat tgactgtaat tcagataaaa agttgatatg
     2821 gaattatgcc ttggaacgaa accttcgtat gatttcagac cgcatttcta aaatggctgg
     2881 ggcgaaaatt attgaaaagc gtttctctta ccgtgactat caaaaatata gagcgactag
     2941 ccataagttt gaactaaagc aacgtcttta ttttttgatg cagcagtcaa aatcctttga
     3001 tgatttttta gaaaaagcag agcaattaca tgttcatatt gattttagtc agaagcatag
     3061 tcgattcatg atgacggatc gggcaatgac aaaaccaatt cgaggacgtc aactcagtaa
     3121 acgagattta tatgatgaag atttttttag aatgcatttt accaagcaag agattgcaag
     3181 tcgtttagaa tttttgttga actgtgtcaa ttctttagaa gggttactaa caaaatcaaa
     3241 agaattgaat ctaaccattg acttaaaaca aaaaaatgta atctttatac ttgaagaaaa
     3301 tggaaagcaa ttcagtctga gtcataaaaa aataagtgat gagaaattat atgatgtcaa
     3361 tttttttcaa gattatttta aaaataagga agtaggtgtt tcagaaggaa tagaaaatct
     3421 acaggcacag taccgtgctt ttcaagaaga acgagataag gagaaggtat ctactgaaga
     3481 aattgaggaa gcctttgaga catttaagga aaaacgagat gccgttcatg aatttgaagt
     3541 aaaacttaca gaacaccaaa ttgagaagtt agttgatgag gggatttata tcaaagtgtc
     3601 ctttggtata aatcagagtg gtcttatttt cattcctaac tatcaactgg atattatgga
     3661 agaagaaaat cagaaaaaat ataaagtcta cattcgtgag acaacctcat attttgtcta
     3721 taacaaagaa cattcggata agaatcagta tatcaaaggg agaaccttga ttaggcagct
     3781 aaccaacgat agtcgagtaa taccatacag aagaccgact gttgaaagac ttcaagaaaa
     3841 gatttctgag attagcctct tgattgagtt aactgagaca gataagaaat accaagacat
     3901 taaagacaac ttggtttccg aaatagcaga gctagatata aaactgactc aaacaaatga
     3961 aaaaattgcc accttaaata agatggcgga agtacttatc aattctaaga gtgaaggttc
     4021 gggtagccaa aaactagcta ggcatgaatt ttctaaattg aacatgacag aatcaacaac
     4081 tttagaacaa gtcaatgaag aacttttgaa gttacaacag gaatttggta atgttcttga
     4141 tgagtatgag aaaacaataa gaaagcttgg acaattattt aaggtttttg atgagtgtat
     4201 caataaagaa attatgaatg aaatataaat cagactgaag acaaactcaa atttttttgg
     4261 atatcttttc tgtttatggt tgccaatatc ggtttaactt ctaaaacaaa cattaataaa
     4321 aatgcattca aagacgattt tacctatttt acgattacgc ttcgacccca aatcattaaa
     4381 gttgtctatg ctctatcatt gcatcactgg acttgtcaag agttaagata attcggagtc
     4441 cactgaaaaa gtcatcgtat gatggtatac taaagatgag gtgatggtat gcttgataat
     4501 cgatgttagt ccctattcta ctctgtgtga tattgttgtt cccaaaactc attttttacg
     4561 acagctaatg gaactctgtg attttagttt tatttatgac gagctggaaa agaattatca
     4621 acctgacttc ggatgtcgtt cctactctct ccttatcatg atgttcaagt atctcttatt
     4681 aaaagacatc tataagttgt ccgatgtgga tgtggtggag cgctcctttt ctggtatgac
     4741 cttcaaatac ttccttggtc tagctcctgt tattgaaccg tcctcattga ctaaattccg
     4801 aaaacttcgg aacaaagatg aacgattact tgatttgctc atcgctaaat ctgttcagat
     4861 tgcgatagag ctcggtctga ttaaaagtaa cattctcatt gtggatgcga ctcataccaa
     4921 agttcattac aatcacaaga aacctcaaga agtcctccga gaacgctcaa aagccttgcg
     4981 taaaacgatt tatcagtatt cggaatatat caaggcagaa tttcctagta agcctcagga
     5041 agatactcta gtagctgaat taagatatac acaagaagta atatcagtcc ttgagaagca
     5101 tgacgaattg actggaatac cagctatctc acaaaattca attaccttaa agaagctgta
     5161 gaggatgact tagagcactt ggaatcctct gtcaaagaag aagcaagaat tggacataag
     5221 tcagccgata gttcctttta cgggtacaaa gagcattttg ccatgaccga tgaacggatt
     5281 attactgcct gtgtggtgac atcgggtgaa aaaagtgatg gtcctgtttt agaagaactc
     5341 tatcacaaat ctaaggataa tggcgtgacg attgaagcta ttgttggaga tagggcctac
     5401 tctgggaagg ataatatgca atttaccaag aaagaacgtg tgcattgagt cgctaggcca
     5461 tatccaacta tttcaaaagg ctttcgtagg aaggaagatg agtttttcta taacaaggac
     5521 gcaggtctct ttgtttgtcc agaagggcat atggcactaa agaaggaaaa gacaggaaga
     5581 aggacggctc aggaaaccca ctattttgac atcaagcact gtcaaatatg cccttcaaaa
     5641 gtgggctgtt ataaagaagg ggctaagtct aagacttatt tgatacccct taagagcgat
     5701 gaacatattt tccagaagag gtttcaggaa gcgccctatt ttaaagaaaa ggccaaacat
     5761 cgctacaaga tagaagccaa aaatgcggaa cttgaaaaca gacatggtct taatgtagct
     5821 agagcaccag gtcttttaaa catggagtta caagccgcca caaccatatt tgtggttaat
     5881 atgaagagga ttataactct aataaaccaa aaataaggaa aagcaaagag gaatctatcc
     5941 aagcaggaga tagatccctc ttttttcatt ttagttgaac tgtagagctt actttttcag
     6001 tggactcgat gattagtgac tatttttttc aaactctatt agttattggt accctaatgc
     6061 cgaatggaga tatttaggat tgtaatagat ttcaatatat ttaaagattt cgttcaatag
     6121 ttgcgaaatt ggcatcattg acaagttctc tttttatgtt ttgtaaaagg attccatggg
     6181 tgcattatca tatggattgc cttttcgact caggctagac ttgcatcttt tctgtttaag
     6241 gagttcttga aatctagctc cagtatattg agatccttga tcggtatggc cgactagttc
     6301 ttatttgaga ttttctctat gataagcttg attgaaaaca ttcgttacca acttatcttg
     6361 cattcgattt cccattgcct aaccaacaat ttttctgcta taaacatata tataatgata
     6421 aataaagagt acctgctttt gtcggaatat aagttaaatc ccccagccag atttcatttt
     6481 taccttttgt ttgaaaacac tgattaatca aattgggtcg tgttaatgag gaatgccgac
     6541 ggctatagta cttgtattta tagcggattc ctttagcata gagacaaa
//
LOCUS       DAVKUR010000080         5912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKUR010000080 DAVKUR010000000
VERSION     DAVKUR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.080"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            109..1809
                     /locus_tag="VW749_001977"
     CDS             109..1809
                     /locus_tag="VW749_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0175952.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            1802..2278
                     /gene="ilvN"
                     /locus_tag="VW749_001978"
     CDS             1802..2278
                     /gene="ilvN"
                     /locus_tag="VW749_001978"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0175953.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2344..3366
                     /gene="ilvC"
                     /locus_tag="VW749_001979"
     CDS             2344..3366
                     /gene="ilvC"
                     /locus_tag="VW749_001979"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0175954.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3473..3709
                     /locus_tag="VW749_001980"
     CDS             3473..3709
                     /locus_tag="VW749_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175955.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            3947..4303
                     /locus_tag="VW749_001981"
     CDS             3947..4303
                     /locus_tag="VW749_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0175956.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            4353..5603
                     /gene="ilvA"
                     /locus_tag="VW749_001982"
     CDS             4353..5603
                     /gene="ilvA"
                     /locus_tag="VW749_001982"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0175957.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1823 a         1002 c         1349 g         1738 t
ORIGIN      
        1 taaacgttaa aatagaaaat tcagaaaatt tcttctttta tcttgaaaaa ttttgaaaaa
       61 atggtatgat agtaacaagt tatttttaag aggaaagaaa ggggaacaat ggagaaaatc
      121 agtttagaat ctcctaagac ggggtcggac ctagttttgg aaacacttcg tgatttagga
      181 gttgatacca tctttggtta tcctggtggt gcggttttgc ctttttatga tgcgatatat
      241 aattttaaag gcattcgcca cattctaggg cgccatgagc aaggttgttt gcatgaagct
      301 gaaggttatg ccaaatcaac tggaaagttg ggtgttgccg tcgtcactag tggaccagga
      361 gcaacaaatg ccattacagg gattgcggat gccatgagcg atagcgttcc ccttttggtc
      421 tttacaggtc aggtggcgcg agcagggatt gggaaggatg cctttcagga ggcagacatc
      481 gtgggaatta ccatgccaat cactaagtac aattaccaag ttcgtgagac agctgatatt
      541 ccgcgtatca ttacggaagc tgtccatatc gcaactacag gccgtccagg gccagttgta
      601 attgacctac caaaagatat atctgcttta gaaacagact tcatttattc accagaagtg
      661 aatttaccaa gttatcagcc gactcttgag ccgaatgata tgcaaatcaa gaaaatcttg
      721 aagcaattgt ccaaggctaa aaagccagtc ttgttagctg gtggtggaat tagttatgct
      781 gaggctgcta cggaactaaa tgaatttgca gaacgctatc aaattccagt ggtaaccagt
      841 cttttgggac aaggaacgat tgcaacgagt cacccactct ttcttggaat gggaggcatg
      901 cacgggtcat tcgcagcaaa tattgccatg acggaagcgg actttatgat tagtattggt
      961 tctcgtttcg atgaccgttt gacggggaat cctaagactt tcgctaagaa tgctaaggtt
     1021 gcccacattg atattgaccc agctgagatt ggcaagatta tcagtgcaga cattcctgta
     1081 gttggagatg ctaagaaggc cttgcaaatg ttgctagcag aaccaacagt tcacaacaac
     1141 actgaaaagt ggattgagaa agtcactaaa gacaagaatc gtgttcgttc ttatgacaag
     1201 aaagagcgtg tggttcaacc gcaagcagtt attgaacgaa ttggtgaatt gacgaatgga
     1261 gatgccattg tggtaacaga cgttggtcaa caccaaatgt ggacagctca gtattatccc
     1321 taccaaaatg aacgtcagtt agtgacttca ggtggtttgg gaacaatggg ctttggaatt
     1381 ccagcagcaa tcggtgctaa aattgctaac ccagataagg aagtagtctt gtttgttggg
     1441 gatggtggtt tccaaatgac caaccaggag ttggctattt tgaatattta caaggtgcca
     1501 atcaaggtgg ttatgctgaa caatcattca cttggaatgg ttcgccagtg gcaggaatcc
     1561 ttctatgaag gcagaacatc agagtcggtc tttgataccc ttcctgattt ccaattgatg
     1621 gcgcaggctt atggtattaa aaactataag tttgataatc ctgagacctt ggctcaagac
     1681 cttgaagtca tcactgagga tgttcctatg ctaattgagg tagatatttc tcgtaaggaa
     1741 caggtgttac caatggtacc ggctggtaag agtaatcatg agatgttggg ggtgcagttc
     1801 catgcgtaga atgttaacag caaaactaca aaatcgttca ggagtcctca atcgctttac
     1861 aggtgtccta tctcgtcgtc aggttaatat tgaaagcatc tctgttggag caacagaaga
     1921 tccgaatgta tcgcgtatca ctattattat tgatgttgct tctcatgatg aagtggagca
     1981 aatcatcaaa cagctcaatc gtcagattga tgtgattcgc attcgagata ttacagacaa
     2041 gcctcatttg gagcgcgagg tgattttggt taagatgtca gcgccagctg agaagagagc
     2101 tgagatttta gcgattattc aacctttccg tgcaacagtg gtagacgtag cgccaagctc
     2161 gattaccatt cagatgacgg gaaatgcaga aaagagcgaa gccctattgc gagtcattcg
     2221 cccatacggt attcgcaata ttgctcgaac gggtgcaact ggatttaccc gcgattaaaa
     2281 atccaactta aatttattaa accagcctaa aaggcaataa ataatagaaa agagagaaaa
     2341 gctatgacag ttcaaatgga atatgaaaaa gatgttaaag tagcagcact tgacggtaaa
     2401 aaaatcgccg ttatcggtta tggttcacaa ggacatgcgc atgctcaaaa cttgcgtgat
     2461 tcaggtcgtg acgttattat cggtgtacgt ccaggtaaat cttttgataa agcaaaagaa
     2521 gatggatttg atacttacac agtagcagaa gctactaagt tggctgatgt tatcatgatc
     2581 ttggcgccag acgaaattca acaagaattg tacgaagcag aaatcgctcc aaacttggaa
     2641 gctggaaacg cagttggatt tgcccatggt ttcaacatcc actttgaatt tatcaaagtt
     2701 cctgcggatg tagatgtctt catgtgtgct cctaaaggac caggacactt ggtacgtcgt
     2761 acttacgaag aaggatttgg tgttccagct ctttatgcag tataccaaga tgcaacagga
     2821 aatgctaaaa acattgctat ggactggtgt aaaggtgttg gagcggctcg tgtaggtctt
     2881 cttgaaacaa cttacaaaga agaaactgaa gaagatttgt ttggtgaaca agctgtactt
     2941 tgtggtggtt tgactgccct tatcgaagca ggtttcgaag tcttgacaga agcaggttac
     3001 gctccagaat tggcttactt tgaagttctt cacgaaatga aattgatcgt tgacttgatc
     3061 tacgaaggtg gattcaagaa aatgcgtcaa tctatttcaa acactgctga atacggtgac
     3121 tatgtatcag gtccacgtgt aatcactgaa caagttaaag aaaatatgaa ggctgtcttg
     3181 gcagacatcc aaaatggtaa atttgcaaat gactttgtaa atgactataa agctggacgt
     3241 ccaaaattga ctgcttaccg tgaacaagca gctaaccttg aaattgaaaa agttggtgca
     3301 gaattgcgta aagcaatgcc attcgttggt aaaaacgacg atgatgcatt caaaatctat
     3361 aactaattag aaatatatag cgctggagat gattttatga aaaagattat gagaaaaact
     3421 gcatcgttat tattggttct agttgtataa tgtaattaca ccgtcggtaa tagtgctagc
     3481 agaccaaaat aaagcagatt ggtcgtatga tgaaaatgct gtaattaaca tttatgatga
     3541 tgctaatttt gaagatggta ggttgcatat gaactttgaa caattcttca aattggcaca
     3601 aatatctaga gaagaaggtc ttgaaattca ttctccgttt gagagagctg gtgcgactaa
     3661 atctgctcgt tatatagcga aatggatttt gagaaataaa aaacattaac aaatatagtt
     3721 ggtaaatcat taggacctaa atcagctgtt agattcggag aagctttatc ctatattgaa
     3781 ggtcctcttc gcagaataaa tgagacgata gatggcggtt tatatcaaat agagcaaatt
     3841 attgcatctg gattgaaaga atcgggttta aatgactgga ctgcgaaaac tttagcttca
     3901 gctattcgtg ggatattaga tgtacttatt taggggttga aatcatatga atattaccaa
     3961 tttgttttct atcaagacag gatgtgatga aactgatagg caactgcaaa aactattttt
     4021 tcagttggat ttacaattgg gagaattgac agatcaacta agaaaattag attctaattt
     4081 tgttcctcgt agtcaatttg tagacacgtt ggatttgaat gatgtagaat ataaagaaat
     4141 tttaaactat tttatcttcc atcgtaatga tagtgaagaa agtttggtag aatggttata
     4201 tgattggatt tccacaaatc gttatgaact tcctaaagag ttttcgattc gtatggctca
     4261 taaataccat gaaagtgtta ctgaagtttt cggagatgaa taactaaaaa acagtcatta
     4321 gtgactgttt tttatagaaa aagaggtttt atatgttaag ttcaaaagat ataatcaagg
     4381 ctcacaaggt cttgaacggt gtggttgtga atactccact ggattacgat cattatttat
     4441 cggagaagta tggtgctaag atttatttga aaaaagaaaa tgcccagcgt gttcgctcct
     4501 ttaaaattcg tggtgcctat tatgccattt cccagctcag caaggaagaa cgtgaacgtg
     4561 gggtagtctg cgcttctgcg ggaaatcatg cgcagggagt agcctatact tgtaatgaaa
     4621 tgaaaattcc tgctactatc tttatgccca ttactacgcc acaacaaaag attggtcagg
     4681 ttcgcttttt tggtggggat tttgtaacta ttaaactagt tggagatacc tttgatgcct
     4741 cagccaaagc agctcaagaa tttacagtct ctgaaaatcg tacctttatt gatccttttg
     4801 atgatgctca tgttcaagca ggtcaaggaa cagttgctta tgagatttta gaagaagctc
     4861 gaaaagaatc gattgatttt gatgctgtct tggttcctgt tggtggtggc ggtctcattg
     4921 ccggggtttc tacctatatc aaggaaacaa gtccagagat tgaggttatc ggagtagagg
     4981 cgaatggagc gcgttccatg aaagctgcct ttgaggctgg aggtccagtc aaactcaagg
     5041 aaattgataa atttgcggat gggattgctg tgcaaaaggt aggtcagttg acctatgaag
     5101 caactcgtca acatattcaa actttggtag gtgtcgatga gggattgatt tctgaaacct
     5161 tgattgacct ttactctaag caagggatag tcgcagaacc tgctggagca gctagtatcg
     5221 cctctttaga ggttttagct gaatatatta aggggaaaac catttgttgt atcatttctg
     5281 gaggaaataa tgatatcaac cgtatgccag aaatggaaga gcgtgccttg atttatgatg
     5341 gtatcaaaca ttactttgtg gtcaatttcc cacaacgtcc aggagctttg cgtgagtttg
     5401 taaatgatat cctggggcca aatgatgata tcacacgttt tgagtatatc aaacgagcta
     5461 gcaagggaac aggcccagta ttaattggga tcgctttagc agataagcat gattatgcag
     5521 gtttgattcg tagaatggaa ggttttgatc cagcttatat taacttaaat ggtaatgaaa
     5581 cgctttataa tatgcttgtc tgaggactaa taaaaaaata tcatattatt tgtacaactg
     5641 atgtatatgt gctataatga agatgaagaa aggggacgat tcctatggtt ttagaaaact
     5701 tatcgtgcaa ttcttacttc tgttcattat agcacttatg atgtttggct cagatttcca
     5761 tccttcattt tgatttccta tctattgaca agcatagtca cactgtcttt aatactcttc
     5821 gaaaatctct tcaaaccacg ttagctctat ctgcaacctc aaaacagtgt tttgagcaac
     5881 ttgcggctag cttcctagtt tgctctttga tt
//
LOCUS       DAVKUR010000081         5892 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKUR010000081 DAVKUR010000000
VERSION     DAVKUR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.081"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            67..309
                     /locus_tag="VW749_001983"
     CDS             67..309
                     /locus_tag="VW749_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0175958.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            311..565
                     /locus_tag="VW749_001984"
     CDS             311..565
                     /locus_tag="VW749_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0175959.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHWRDIY"
     gene            612..1264
                     /locus_tag="VW749_001985"
                     /pseudo
     CDS             612..1264
                     /locus_tag="VW749_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1524..2510)
                     /locus_tag="VW749_001986"
     CDS             complement(1524..2510)
                     /locus_tag="VW749_001986"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0175960.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2704..5172
                     /gene="gyrA"
                     /locus_tag="VW749_001987"
     CDS             2704..5172
                     /gene="gyrA"
                     /locus_tag="VW749_001987"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0175961.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5172..>5892
                     /gene="srtA"
                     /locus_tag="VW749_001988"
     CDS             5172..>5892
                     /gene="srtA"
                     /locus_tag="VW749_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0175962.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFN"
BASE COUNT         1847 a          971 c         1291 g         1783 t
ORIGIN      
        1 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
       61 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
      121 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
      181 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
      241 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
      301 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
      361 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
      421 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
      481 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
      541 tggtcattgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
      601 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgatata acaattattt
      661 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
      721 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
      781 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
      841 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
      901 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
      961 caggtaaatt agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     1021 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     1081 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     1141 atattgttcc agtttccctt tttgggaaga cgaattatcg agccaaagaa tattaataga
     1201 gaaacaatcc gagaagatag aagaactgca tcggatgata caagatttgc ttgaaaaaac
     1261 ataataaaaa taaagatgag acaaagtttg agttgaggag aaatcaagta agttttgaca
     1321 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaatga
     1381 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     1441 atggggggct atttcaactt caacctacta taatacagaa aaaaacaact ccctgataat
     1501 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tgggtttttc
     1561 catgcttcgt caatgatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
     1621 gcgtcgttca atgggatatt tactggacga acaataccat gtgcaccaac aacagctggt
     1681 tgaccgataa agacgttctc aactccgtat tgaccttctt ggaatactga aagtggaagt
     1741 actgcatttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
     1801 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
     1861 aattcaatca attcagcttc ttgaacattt tgagtatctt taaggaattc ttcaaggttt
     1921 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
     1981 atgtaggcgt gaactgaacg agcatctacg tccaattttt cagcaagtgc ttgacggaaa
     2041 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
     2101 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
     2161 aaacctgatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
     2221 aggtcaagac gagtttcacc tggtttttga ggcgcacctg cagtgatcac aacaaggtca
     2281 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
     2341 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
     2401 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
     2461 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
     2521 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
     2581 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
     2641 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
     2701 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
     2761 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
     2821 aaacctgttc accgtcgcat tctttacgga atgaatgaat tgggtgtgac cccagacaaa
     2881 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
     2941 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
     3001 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
     3061 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
     3121 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
     3181 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
     3241 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
     3301 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
     3361 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
     3421 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
     3481 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
     3541 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
     3601 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
     3661 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
     3721 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
     3781 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
     3841 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
     3901 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
     3961 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
     4021 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
     4081 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
     4141 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
     4201 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
     4261 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
     4321 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
     4381 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
     4441 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
     4501 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
     4561 gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
     4621 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
     4681 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
     4741 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
     4801 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
     4861 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
     4921 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
     4981 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
     5041 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
     5101 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
     5161 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
     5221 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
     5281 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
     5341 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
     5401 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
     5461 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
     5521 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
     5581 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
     5641 tagataatgc taaaaatggc atgaagattt atctaactga taaaaataaa gtttatactt
     5701 atgaaatacg tgaagtcaaa cgtgtgacac cagatcgtgt tgatgaagtt gatgatagag
     5761 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
     5821 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
     5881 cagctttcaa tc
//
LOCUS       DAVKUR010000082         5849 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKUR010000082 DAVKUR010000000
VERSION     DAVKUR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.082"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            88..1611
                     /locus_tag="VW749_001989"
     CDS             88..1611
                     /locus_tag="VW749_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016648332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175963.1"
                     /translation="MFSHILGFRLETNLRKRGIDGLEKASFRFFDLNPSGQIRKIIDD
                     NAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGIILLALTIIGGLILGAMMGE
                     QEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFKSFYKAIKDYSKYAYDYSLS
                     CKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLELIMILFLSGVLFVSFMRMM
                     WYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNYNIEFENVSFAYNDKAVIEN
                     LSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSIKIGGIAISEYSDEALIKAI
                     SFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGCDLILDKFPERENTIIGSKG
                     VYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEFELQKAFKNLMKDKTVIMIA
                     HRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSLQEMFNSANEWRVSNERVL"
     gene            1595..3316
                     /locus_tag="VW749_001990"
     CDS             1595..3316
                     /locus_tag="VW749_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175964.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDVK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3327..3911
                     /locus_tag="VW749_001991"
     CDS             3327..3911
                     /locus_tag="VW749_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0175965.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            3911..4606
                     /locus_tag="VW749_001992"
     CDS             3911..4606
                     /locus_tag="VW749_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0175966.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4594..>5849
                     /locus_tag="VW749_001993"
     CDS             4594..>5849
                     /locus_tag="VW749_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175967.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMI"
BASE COUNT         2117 a          758 c         1108 g         1866 t
ORIGIN      
        1 aattcaaatt tatccggtgc agagagtata gcattaaaat ctgttattac actaacaagt
       61 ggagcgatat tttattttgt ctcaggaatg ttttcacaca tcttgggatt taggcttgaa
      121 acaaatttaa gaaaaagggg aattgatggc ttagagaaag caagttttag gttctttgac
      181 ttaaatccat ctggtcaaat aagaaagatc atagatgata atgcagcaca aactcatcag
      241 gtggtagcac acatgattcc cgatagttct caggcaataa tcacacccgt acttgtactt
      301 gcacttggct ttatagtaag tataagagtt ggcataattt tgcttgctct tactataatt
      361 ggcggcttaa ttttaggggc aatgatgggc gagcaagaat ttatgaagat ataccaagaa
      421 tccctatcta aactaagtgc tgaaactgtt gagtacgtga gaggaatgca agttgtaaaa
      481 atatttaaag caaatgtaga gtcttttaaa agcttttata aggcgataaa agattactca
      541 aagtatgctt atgattattc cctatcttgt aaaaggcctt atgttttgta tcaatggtta
      601 ttttttggac tgattgcaat tttaattatt cctatagttt attttatgac tagcttagct
      661 agcgcaaagg tgattttact tgagcttatc atgattttat ttttatcagg agttctcttt
      721 gtttcattca tgagaatgat gtggtactcc atgtatattt ctcaaggaaa ttatgcagta
      781 gatactttag aggcgcttta cgaagatatg caaaaagaca aattagtgca tggtaatatc
      841 aataatttta aaaactataa tatagaattt gagaatgtta gctttgctta taatgataaa
      901 gctgtcattg aaaatttatc ctttaattta gaagaaggaa agtcctacgc acttgtcggt
      961 tcatctggat caggcaaatc aacagtagca aaacttatat caggttttta taatgttaat
     1021 aaaggaagca taaagatagg cgggatagca ataagtgaat attctgacga agccttaatt
     1081 aaagccattt cctttgtttt tcaagattca aaattattca agaagagcat ttatgataat
     1141 gtagctttag ctaataaaga tgcgacgaaa gatgacgtta tgagagcctt aaaattagca
     1201 ggatgcgatt taatattaga caaattccca gaaagagaaa atacaatcat aggctcaaaa
     1261 ggtgtttatt tatccggtgg agaaaaacaa agaattgcaa ttgctagagc aattttaaag
     1321 gattccaaaa ttattattat ggatgaagca tcagcatcta ttgacccaga taacgagttt
     1381 gaattgcaaa aagcttttaa aaatcttatg aaggataaaa cagttatcat gattgcacac
     1441 aggctatcta caattaaaga ccttgatgaa attattgtca tggatagtgg aaaaattata
     1501 gaaagagggt ctgacaaaga attaatgtca aaagatacaa ggtataagag cctgcaagag
     1561 atgtttaaca gtgcgaatga atggagggtt tcaaatgaaa gagttttata aaaaaagatt
     1621 tgctcttaca gatggaggag caagaaattt aagtaaagca acactggctt catttttcgt
     1681 ttattgtata aacatgcttc ctgccatatt acttatgatt tttgctcagg aagttttgga
     1741 aaatatgggc aaaagcaatg gcttttatat agtattctca gttttgactt tgatagcaat
     1801 gtatattttg ctttctatcg aatacgataa attatataac acaacctatc aagaaagtgc
     1861 agatttaaga ataaggacag cggagaattt atcaaaatta cctctatctt acttttctaa
     1921 acatgacatt tccgacattt cacaaacaat catggctgat attgaaggca tagagcatgc
     1981 aatgagccac tcaataccaa aggtgggcgg catggtactg tttttcccat taatatctgt
     2041 aatgatgcta gcgggcaatg tcaagatggg tttagctgta attattccat ctattttaag
     2101 ctttatattt atacctttat ctaaaaaata tcaggttaat ggacagaata gatattatga
     2161 tgtcttaaga aaaaactcag aaagctttca agaaaatatc gaaatgcaaa tggagattaa
     2221 agcatataat ttatcgaagg atattaaaga tgacttatat aaaaaaatgg aagatagtga
     2281 gagagtacac ttaaaggcgg aagtaactac aattttaact ttgtctatat cttcaatatt
     2341 tagctttata tctcttgctg ttgtgatatt tgtcggcgta aatctaatta ttaataaaga
     2401 gataaattct ctctacctta taggatattt actagctgct atgaagataa aagactcttt
     2461 agatgcatct aaagagggct tgatggaaat attttattta tcgcccaaaa tagaaagatt
     2521 aaaagaaatt caaaatcaag atttacaaga aggcgatgac tatagcttaa aaaaatttga
     2581 tattgatcta aaagatgttg agtttgccta caataaagac gcaaaagttt taaatggtgt
     2641 aagttttaaa gctaagcagg gagaggtcac tgctttggta ggtgcaagtg gctgcggtaa
     2701 aacaactatc ttgaaactta tatcaagact ttatgattat gacaagggac aaatcttaat
     2761 cgatgtcaaa gatataaaag aaatatcaac agaatctctt tttgataagg tctctatagt
     2821 tttccaagat gtggttctct ttaatcaaag cgttatggaa aatattagaa tcggaaagca
     2881 agatgcaagt gacgaagagg ttaaaagagc agcaaaactt gcaaattgca cagattttat
     2941 agaaaaaatg gataaaggtt tcgatacagt tattggtgag aacggagctg agctatcagg
     3001 aggagaaaga caaagattat caatagccag agccttctta aaagatgcgc cgatattgat
     3061 cttagatgag ataacagcaa gccttgatgt taacaacgag aaaaagattc aagagtcttt
     3121 aaataattta gttaaagata aaactgttgt aatcatttca catagaatga aatccataga
     3181 aaatgcagac aagatagtag ttcttcaaaa cggaagagta gaaagcgaag gtaagcatga
     3241 agagctttta caaaaatcaa aaatttacaa aaatttaata gaaaagacaa aaatggcaga
     3301 agaatttatt tattaggagg actacaatgg ataataaaaa attaaaagta aaagatttag
     3361 taagtatcgg tgtttttggc gtaatttatt ttgccttcat gtttggagtt ggtatgatgg
     3421 gcttgattcc aatattgttc ttaatatacc cgacagtatt agccatagtt gcaggaactg
     3481 ttgttatgtt atttatggct aaggttcaaa agccatgggc actatttata tttggtatga
     3541 tatcaccact tgtgatgttt gcagctggtc atacctacgt agttgtggtt ttatcactta
     3601 tagtaatgat aatagcagaa ttaattagaa agattggtaa ttataattca tttaaataca
     3661 atatgctttc ttatgcaatc ttcagcacat ggatatgtag ctctttaatg caaatgcttt
     3721 tagcaaaaga aaaatatatg gagtggtctt tgatgacgat gggaaaagat tatgttgatg
     3781 tattagaaaa gttaataact tatcctcaca tggctttagt agccttaggt gctttcttag
     3841 gaggaattct tggagcatat ataggcaagg ctctattgaa aaaacacttt gaaaaagcag
     3901 gcatcgtata atgcctactt tttcttcaaa tgctcccttt aatcccaatc cgatctctaa
     3961 gatattagtc gtatttatca caggcttaac tgttatgcat agcataaaca tccgttttga
     4021 gctggcaatt gtttgtctta ttggtatttt gctttatttg aatggataca aaaaaacact
     4081 tttcaaatgg attatattgt gtgggatact ttactccttg cctaatttta tggtgttatc
     4141 tgaattaaac cctatagtta agatgttttt gagtatacct attgttatta gaatgtttat
     4201 tttaccattt atggcagcaa gctttatgat aaagacctcg gatgtaggcg caataatttc
     4261 atcgatggat aagcttaaga tttcaaagaa tgtatccata cctattgcgg ttatgtttag
     4321 attcttccca tcttttaagg aggagaagaa aaacatcaaa atagctatga gagtaagagg
     4381 gataaatttt aaaaacccag tcaaatatct tgaatatgtt tctgtgccac tactcattat
     4441 atcatctaat atatcagatg acattgcaaa agcggcagaa acaaaggcaa tagaaaatcc
     4501 aattgccaag accagataca ttcgcgtaaa gatacagcta attgattttg tttatgtttt
     4561 agcggttgct ggacttattg tgggaggctt aatatggttg aaataaaaaa tttaagtctt
     4621 gattatggtg aagagcatat attagatgat atatcactat ccatagccga gggagagtgc
     4681 gtgctattta caggaaaaag tggaagtggt aagtcatctt taataaattc aatcaatgga
     4741 ctagctgtaa ggtatgataa cgcaaagaca aagggcgaaa taattattga tggtaagaat
     4801 ataaaaaatt tggaacttta tcaaatctca atgcttgttt caactgtttt tcaaaatcct
     4861 aagacatatt tttttaatgt caatacgaca ttagaattat tattttattt ggaaaatatc
     4921 ggtcttgcaa gagaagagat ggacaggcgt ttgaaggata tgcttgagat attcccgata
     4981 aaaaatcttt tgaacagaaa tatatttaat ctatccggcg gtgaaaaaca aattctttgc
     5041 attgcagctt cttatatagc aggtacaaag attatagtta tggatgagtc ttcatcgaat
     5101 ttagatatta aaagcataag tgttttggca aagatgctaa agatattaaa agagaaaggc
     5161 ataagcataa ttgttgcaga gcatagaatt tattatttga tggacatagt tgaccgtgta
     5221 tttttaatag ataaaggaaa gcttaaaaaa acttatacta gaagtgaatt tttaaagcta
     5281 gataaaaatg aattaaatgc tttaagttta agagataaag aattaagtaa attaaaagtt
     5341 ccttatttaa aagaaggtgg agagtatcag ataaaaaatc ttagctacaa atttactgat
     5401 gatgagtgtt taagcttaaa agatatttcg ttcaagcttg ggaaaattta tggcataata
     5461 ggatccaacg gacgaggaaa atcaacgctt ttaagatgtt taataggtct tgagaaaaaa
     5521 tcaaaagaag aaatttattt taagggagag aagctatcta aaaaagaaag actcaaaaac
     5581 tcttcacttg ttatgcaaga tgtaaatcat caattattca cagatgaagt attcaacgag
     5641 cttagattag gagtaaagaa ttttgatgaa gaaaaggcga aaatcatttt aaaagattta
     5701 ggcctggacg aatttattga aaggcatccg atgagtttat caggagggca aaagcaaagg
     5761 cttgcaatag catctgttat gtgcaagaat tctccatttg tcttttttga cgaaccttca
     5821 agtggtatgg attattccaa tatgataaa
//
LOCUS       DAVKUR010000083         5747 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKUR010000083 DAVKUR010000000
VERSION     DAVKUR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.083"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            162..683
                     /locus_tag="VW749_001994"
                     /pseudo
     CDS             162..683
                     /locus_tag="VW749_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(676..843)
                     /locus_tag="VW749_001995"
     CDS             complement(676..843)
                     /locus_tag="VW749_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV0175968.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(1008..2615)
                     /locus_tag="VW749_001996"
     CDS             complement(1008..2615)
                     /locus_tag="VW749_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0175969.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2768..4252
                     /locus_tag="VW749_001997"
     CDS             2768..4252
                     /locus_tag="VW749_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0175970.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4347..4829
                     /locus_tag="VW749_001998"
     CDS             4347..4829
                     /locus_tag="VW749_001998"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0175971.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(5116..5337)
                     /locus_tag="VW749_001999"
                     /pseudo
     CDS             complement(5116..5337)
                     /locus_tag="VW749_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         1689 a         1286 c         1073 g         1699 t
ORIGIN      
        1 atttttttta ctatctgcat ctttaagtat cttagtagac ttcccgcgaa acaaaaatat
       61 agtaaaatga aataagaaca tgacaaatcg atcaggacag tcaaatcgat ttctaacaat
      121 gttttagaag cagaggtcta ctactctagt ttcaatctaa ttatgaacaa gacccagaaa
      181 aagtagcctt atttcttaag aattttaata gtttaaagca cctagcacct gtttagattg
      241 atgaaacagg attcgatact tatttttatc gagaatatgg tcgctcatta aaaggtcagt
      301 taagaagagg caaagtatct ggaagaagat atcagaggat ttctttggtt gcaggtctaa
      361 caaatggtga attaatcgct ccaatgactt acgaagagat gatgacgagc gacttttttg
      421 aagtatggtt tcagaagttt ttcttaccaa cattaaccac accatcggtt attattatgg
      481 ataatgcaag attccataga atggggaagc tagaactttt atgcgaagag tttgggcata
      541 aacttttacc tcttcctccc tactcacctg agtacaatcc tattgagaaa acatgggctc
      601 atatcaaaaa gcacctcaaa aaggtattac caagttgcaa taccttttat gaggctcttt
      661 tgtcttgttc ttgtttcaat tgactatatt atcagcgtaa tagtctaata gatagttaaa
      721 tgtagttgga tttccactaa aggttgatga gtaagttttt gtatctgaac ctgattggtc
      781 gcaagcagct aaaagcaaag cagatgtaaa agtcaggcct gcactaagga tacgcttctt
      841 tatgttcgtc ttctttctcc ttaatagtgg gaatttgtaa agttaattga atttcgagaa
      901 tgaaggttta taaaccttgg ttataaaaaa caaaggattt ctgcctttta tacagtcctc
      961 ccttgttttt atacgatttc aattttaaat ttttctgcaa aaaatattta tagtaattcc
     1021 acacagaaag catcccatgg aactaagatt tgtttttcaa agacttcttg agctagggtg
     1081 ttttcaatca agacagattt gacttttcct tctactgtca agtcttgctc ttcattggac
     1141 aagttagcca caactaggaa gcgacggtcg ccatccttac gtatataagc aaagacctta
     1201 tcagccgtat caagcaattc aaagtcagct cgaattagcc agctattctc cttgcgaatt
     1261 tggaccagtt tctgataggt atagaaaata gaatctggat ttgccagcgc ttcttggacg
     1321 ttgatcatct cgtaatttgg attaactgcc aaccaaggtt gacctgttga gaaaccagcg
     1381 tttttgctct cgtcccattg cataggggta cgggcattgt cacgtccaat aacacggata
     1441 ctgtccatga tttcttcaat cggaacacct ttttcaagag cctcacgcgc atagttgaga
     1501 gattcaatat cttctacttg atccagtgtt tcaaacggat agttggtcat cccaatctcc
     1561 tcaccttggt agatataagg agttcctctc atgagatgaa gtaagattgc aaaggctttg
     1621 gcagattttt cgcggtattc ttggtcattt ccccagattg agacaatacg agggaggtca
     1681 tggttgttcc agaagaggga attccagccg tcctcaactc ctaactctgt ctgccatttg
     1741 ttgaagattt cttttaactt agcgatattc agctcttttt gatagtgcca tttaggttga
     1801 ccttcctgat actgaagacc gatatgttca aactggaaga ccatagacaa ttcttgcccc
     1861 tttggatcag agtagagttt ggcaatctct ggcgttgctc cccaagtctc ccctactgtc
     1921 aagagatcct tatctccaaa ggtcgcctga ttcatttcct tgagataggg atggagcata
     1981 ggaccattat tgactacctt ctcgtcagga attttgccaa tcatgtcaat aacatccata
     2041 cggaaaccac caataccctt atcaatccag aagttcatca tctcataaat tttctggcga
     2101 agtttttcat tttcccagtt gagatccggc tgtttcttgc tgaaaaagtg gagatagtat
     2161 tgacctgact tttcatcgta ttcccaagca gacccactaa agatagaatc taaatcgtta
     2221 ggctcatccc gccagatata gtagtctcgc tcagggctat taggattttc acaggcctct
     2281 acaaaccagg catgctcatc cgaggtatga ttgaccacca agtccatgat gatacggata
     2341 tcacgcttct tagcttctgc aatcagttca tccatgtcct ccatggttcc aaaaatagcc
     2401 gcaatcgctt gataatcagc aatatcatag ccattatcat ccatagggct gtcataaacg
     2461 ggagaaagcc aaatcgctgt gattcctagc ttagctagat agtccaactt actggtaata
     2521 cctggcaaat caccaactcc atctccatta ctatccataa aactctttgg atagacttga
     2581 tagactacgg cattatgcca ccatttttct tgcatctgtt tacctcatta ttttaataat
     2641 ctatagtata tgatagcact ttttaaaatt ttgtgcaagc gtttgcttaa tctttttaat
     2701 ttctttttta gctccgtagt ttcctaactt ccaatttttt attataatag aatccagagg
     2761 taaaaaaatg aaaaaacaag cttttagttc tgaacagtat ttgaatttac aacgcgacca
     2821 catcttagag cgcattaacc aatttgacgg caagctctac ttagagtttg gcggtaaaat
     2881 gttagaagat ttccacgctg ctcgtgtcct tcctggttat gaacctgaca acaaaatcaa
     2941 gctcttgcaa gaattgaaag agcaggttga ggttgtgatt gccattaatg ctagcaacat
     3001 tgaacattcc aaagcacgtg gcgacttagg catttcttat gaccaagaag ttcttcgttt
     3061 gattgacaaa ttcaatgaat tagggatttt tgttggttcc gttgtcatta cacaatacgc
     3121 tggccaactc gctgcagatg ccttccgcaa ccaacttgag aaaaacggaa ttgattctta
     3181 tcttcattat ccaatcaaag gatatccgac ggatatggat cacatcattt ccccagaagg
     3241 catgggcaaa aacgactaca tcaaaaccag tcgcaacttg attgtcgtaa ccgctcctgg
     3301 acccggttct ggaaaattgg caacgtgtat gtccaatatg taccacgacc aaatcaatgg
     3361 catcaagtct ggctacgcta aatttgaaac cttccctgtt tggaatcttc cccttcatca
     3421 tccagttaac ttggcttatg aagctgccac agctgacctt gatgatgtca acatgattga
     3481 ccccttccat cttcaaacct atggagaaac cactgtcaac tacaaccgtg atatcgaaat
     3541 cttcccagtg ctcaagcgca tgttggaacg tattctcgga aaatcaccat acgcttcacc
     3601 gacagatatg ggtgtcaaca tggttggttt cgctattaca gatgacgagg ctgctgtcga
     3661 agcttctaaa caagaaatca tccgccgtta ctatcaaaca gttcttgact tcaaagctga
     3721 aaaagttggc gaagctgccg tcaagaaaat tgagttgctc atgaacgacc tcggtatcac
     3781 acctgcagac cgtaaggttg ctgtcgttgc gcgccaaaaa gcagaagaaa ctggtggacc
     3841 agccctagcc tttgaattgc caaatgggga aatcgtcact ggtaagaact cagaactctt
     3901 tgggcctaca gccgctgcct tgatcaacgc catcaaaaaa tcagctgaca tcgctaaaga
     3961 agtaaaacta atcgagcctg aagttgttaa gccaatccaa ggtcttaaaa tcgatcatct
     4021 cggtagccgc aatccacgcc ttcattcaaa tgaaatcctg attgcacttg ctatcacagc
     4081 tacagaaaat cctgatgctg cccgcgctat ggaagaactc ggcaacctca aaggaagcga
     4141 agcccactca accatcatct tgactgatga agacaagaat gtccttcgta aactgggtat
     4201 caacgtaacc tttgacccat actaccaata cgaccgctta tatcgtaagt aaagatttca
     4261 acctctccag cctcggagag gttttctctc tgtctcagga gcaaccttta tgatataatg
     4321 agagaagaaa actgaaagga tttaccatgt caaaagaagt tattgtcgaa agttttgaac
     4381 ttgaccacac cattgtcaaa gcaccctatg ttcgcttgat tggggaagaa acaggaccaa
     4441 aaggagacat catctccaat tatgatattc gcttggtgca accaaacgaa gactctatcc
     4501 ctactgccgg ccttcacact atcgagcacc tcttagccaa actcatccgt acccgcattg
     4561 acggcatgat tgactgttca ccatttggtt gccgcacagg cttccacatg attatgtggg
     4621 gacgtcacac cagtgctaaa atcgcagctg ttatcaagga ttcgctcaag gaaatcgctg
     4681 aaactactac ttgggaagat gtcccaggga caaccatcga atcttgcgga aactacaagg
     4741 accacagcct cttctctgct aaagaatggg caaaactcat cttggaacaa gggatttcag
     4801 atgatgcctt tgaacgtcat gtgatttaaa atcgagtagg ggataatctc tagcccctct
     4861 cacaccaccg tacgtaccgt tcggcatacg gcggttcaac taacttttta acgcatgtcg
     4921 ttcaaggtaa taatccaaac acgaaaccaa tccacgtttt tcaaggactg gttttgatat
     4981 agcacgttta agtaccgact tctgagctac tatagtggat tgaaactaga atagttcacc
     5041 tctgcttcta aaacattgtt agaaatcgat ttgactatcc tgatcgattt gttctattct
     5101 tatttcattt tactataatt gatagtggtc gccccagcca gataccttat ctgctatcca
     5161 tttaggaacc cctaacttaa gcaatcccca taatcgtctc gatttcttct tccattgctt
     5221 ccagataatc actcgtaggc gagtatgcaa acgctcatct atgctggtga ctatactttt
     5281 catatttccc aatgaaaaat agtttatcca tcctcgaatg gacaaattca gttgctctcg
     5341 tgatttacgc atataggtta cgactacctt tttggacttt agagtttgag gcccccttat
     5401 ccgctatata cgccttacta tcacgttcct gttcgtagag ccacgagttc gctatccctt
     5461 cctctgacga ttcttatttc cagcgtcaga cttaaaacgg tctatcccca gaccgtttta
     5521 atccgctacc tcacgatagt caggcttggg aatcgctatt gggttcaccg gtaacaggtg
     5581 cccaccgagg acttacacct cagatatata gtaaaatgaa ataagaacag gacaaatcga
     5641 tcaggacagt caaatcgatt tctaaaaatg ttttagaagt agatgtgtac tattctagtt
     5701 tcaacctact atacgacatg cccgtcgtac ctcaaaagga accagtt
//
LOCUS       DAVKUR010000084         5524 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKUR010000084 DAVKUR010000000
VERSION     DAVKUR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5524
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.084"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            184..1164
                     /locus_tag="VW749_002000"
     CDS             184..1164
                     /locus_tag="VW749_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0175972.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            1969..2196
                     /locus_tag="VW749_002001"
     CDS             1969..2196
                     /locus_tag="VW749_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175973.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            2484..5381
                     /gene="nanA"
                     /locus_tag="VW749_002002"
     CDS             2484..5381
                     /gene="nanA"
                     /locus_tag="VW749_002002"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0175974.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1802 a          956 c         1213 g         1553 t
ORIGIN      
        1 caaaaaacta gtataaacag aagagagagc gaaatgctct tttttcgttt ctaaaactac
       61 tttcagccca tcatcctaaa agtaaagaat ctaaattcac tttctattta cccttctttc
      121 ttgcattgat tacatagata tgctacagtt gtggtaacga ttacaaaata aaaggagcat
      181 gctatgaaaa atccagcttt gctagaagaa attaagacct atagaggaag ggatgaggtt
      241 ccggaagact ttgatgattt ctgggatggg gaagtgaaaa atgtttccac gcttccatcc
      301 taccacttgg aggaaagaga tttccacatt cctcaagtca agtgctatga gttaacattt
      361 gaaggaagca agaaaggaaa ggtctatgca cgcattgttc ttccaaagag tgaggagaag
      421 gttccactaa tcttccattt tcatggttat atgggacgtg gctgggactg ggccgacatg
      481 ctgggcttca ccgtagctgg ttacggtgtt gtttccatgg atgtgcgggg ccagtcaggt
      541 tactcacaag acggcttgcg ttctccttta ggaaataccg tgaaggggca tattatccgt
      601 ggtgctgtgg aaggtcggga ccacctcttt tataaggatg tttatctgga tatttaccag
      661 ttggtcgaaa ttgttgctag tctgtctcag gttgatgaga agcgtctttc tagctatggt
      721 gcctcacaag gaggggctct agctctagtt gcagcagcgc tcaatcctcg aattcagaaa
      781 acagttgcca tttatccctt cttgtcagac ttcagacggg tgattgagat tggtaatact
      841 agcgaggctt acgacgaact tttccgttat ttcaagtttc acgacccctt ccatgaaaca
      901 gaggaggaaa tcatggcgac ccttgcctat atcgatgtca aaaatcttgc ccatcgtatc
      961 caaggtgagg ttaagatgat tacgggcttg gacgacgatg tttgctatcc cattacccag
     1021 tttgcgattt ataatcgtct gacctgcgat aaaacctatc gcatcatgcc tgagtatgct
     1081 cacgaagcca tgaatgtatt tgtcaatgac caagtctaca actggctctg tggaagtgag
     1141 attcctttta aatatctaaa ataaggagtc gactctaagc acaaaatctt aaaaattaca
     1201 aacacgcata gtatcagggg attaagaaaa cttgatacta tgcgttttat catggaaata
     1261 tagtaaaatg aaacaagaac aggacaaatc gatcaggaga gtcaaatcga tttctaacaa
     1321 tgttttagaa gtagatgtgt actattctag tttcaatcta ttatatttat agaatttttt
     1381 gttgctagat ttgtcaaatt gcttaaaata atttttttca gaaagcaaaa gccgatacct
     1441 atcgagtagg gtagttcttg ctatcgttag gcttgtctgt aggtgttaat acttttcaaa
     1501 aatctcttca aaccacgtca gcttcgcctt gccgtatata tgttactgac ttcgtcagtt
     1561 ctatctgcca cctcaaaacg gtgttttgag ctgactttgt cagtcttatc tacaacctca
     1621 aaacagtgtt ttgagcatca tgcggctagc ttcttagttt gctctttgat tttcattgag
     1681 tataaaaaca gatgagtttc tgttttcttt ttatggacta taaatgttca gctgaaacta
     1741 ctttcaagga cattattata taaaagaatt ttttgaaact aaaatctact atattacact
     1801 atattgaaag cgttttaaaa atgaggtata ataaatttac taacacttat aaaaagtgat
     1861 agaatctatc tttatgtata tttaaagata gattgctgta aaaatagtag tagctatgcg
     1921 aaataacaga tagagagaag ggattgaagc ttagaaaagg ggaataatat gatatttaag
     1981 gcattcaaga caaaaaagca gagaaaaaga caagttgaac tacttttgac agtttttttc
     2041 gacagttttc tgattgattt atttcttcac ttatttggga ttgtcccctt taagctggat
     2101 aagattctga ttgtgagctt gattatattt cccattattt ctacaagtat ttatgcttat
     2161 gaaaagctat ttgaaaaagt gttcgataag gattgagcag gaagtatggt ataaatagca
     2221 taagctgatg tccatcattt gcttataaag agatatttta gtttaattgc agcggtgtcc
     2281 tggtagataa actagattgg caggagtctg attggagaaa ggagagggga aaattggcac
     2341 caatttgaga tagtttgttt agttcatttt tgtcatttaa atgaactgta gtaaaagaaa
     2401 gttaataaaa gacaaactaa gtgcattttc tggagtaaat gtcttatttc agaaatcggg
     2461 atatagatat agagaggatc agtatgaatc ggagtgttca agaacgtaag tgtcgttata
     2521 gcattaggaa actatcggta ggagcggttt ctatgattgt aggagcagtg gtatttggaa
     2581 cgtctcctgt tttagctcaa gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac
     2641 tttcggggga gagctcaacc ctaactgata cagaaaagag ccagccttct tcagagactg
     2701 aactttctgg caataagcaa gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa
     2761 gagattacta tgcacgagat ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg
     2821 aaaccaatgc ttcaaatggt cagagagttg atttatcaag tgaactagat aaactaaaga
     2881 aacttgaaaa cgcaacagtt cacatggagt ttaagccaga tgccaaggcc ccagcattct
     2941 ataatctctt ttctgtgtca agtgctacta aaaaagatga gtacttcact atggcagttt
     3001 acaataatac tgctactcta gaggggcgtg gttcggatgg gaaacagttt tacaataatt
     3061 acaacgatgc acccttaaaa gttaaaccag gtcagtggaa ttctgtgact ttcacagttg
     3121 aaaaaccgac agcagaattg ccaaatggtc gagttcgcct gtatgttaat ggtgttttat
     3181 ctcgaacaag tctgaaatct ggcaatttca ttaaagatat gccagatgta acgcatgtgc
     3241 aaatcggagc aaccaagcgt gccaacaata cggtttgggg gtcaaatcta cagattcgga
     3301 atctcactgt gtataatcgt gctttaacac cagaagaggt acaaaaacgt agtcaacttt
     3361 ttaaacgctc agatttagaa aaaaaactac ctgaaggagc ggctttaaca gagaaaacgg
     3421 acatattcga aagcgggcgt aacggtaaac caaataaaga tggaatcaag agttatcgta
     3481 ttccagcact tctcaagaca gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc
     3541 tccattcgag tgactggggt gatatcggta tggtcatcag acgtagtgaa gataatggta
     3601 aaacttgggg tgaccgagta accattacca acttacgtga caatccaaaa gcttctgacc
     3661 catcgatcgg ttcaccagtg aatatcgata tggtgttggt tcaagatcct gaaaccaaac
     3721 gaatcttttc tatctatgac atgttcccag aagggaaggg aatctttgga atgtcttcac
     3781 aaaaagaaga agcctacaaa gaaatcgatg gaaaaaccta tcaaatcctc tatcgtgagg
     3841 gagaaaagga agcttatacc attcgagaaa atggtactgt ctatacacca gatggtaagg
     3901 cgacagacta tcgcgttgtt gtagatcctg ttaaaccagc ctatagcgac aagggtgatc
     3961 tatacaaggg tgaccaatta ctaggaaata tctacttcac aacaaacaaa acttctccat
     4021 ttagaattgc caaggatagc tatctatgga tgtcctacag tgatgacgac gggaagacat
     4081 ggtcagcgcc tcaagatatt actccgatgg tcaaagccga ttggatgaaa ttcttgggtg
     4141 taggtcctgg aacaggaatt gtacttcgga atgggcctca caagggacgg attttgatac
     4201 cggtttatac gactaataat gtatctcact taaatggctc gcaatcttct cgtgtcatct
     4261 attcagatga tcatggaaaa acttggcatg ctggagaagc ggtcaacgat aaccgtcagg
     4321 tagacggtca aaagatccac tcttctacga tgaacaataa acgtgcgcaa aatacagaat
     4381 caacggtggt acaactaaac aatggagatg ttaaactctt tatgcgtggt ttgactggag
     4441 atcttcaggt tgctacaagt aaagacggag gagtgacttg ggagaaggat atcaaacgtt
     4501 atccacaggt taaagatgtc tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa
     4561 aagaatacat catcctcagt aatgcaggtg gaccgaaacg tgaaaatggg atggtccact
     4621 tggcacgtgt cgaagaaaat ggtgagttga cttggctcaa acacaatcca attcaaaaag
     4681 gagagtttgc ctataattcg ctccaagaat taggaaatgg ggagtatggc atcttgtatg
     4741 aacatactga aaaaggacaa aatgcctata ccctatcatt tagaaaattt aattgggaat
     4801 ttttgagcaa aaatctgatt tctcctaccg aagcgaaagt gaagcgaact agagagatgg
     4861 gcaaaggaga gatgggcaaa ggagttattg gcttggagtt cgactcagaa gtattggtca
     4921 acaaggctcc aacccttcaa ttggcaaatg gtaaaacagc gactttccta acccagtatg
     4981 atagcaagac cttgttgttt gcagtagata aggaagatat cggacaggaa attattggta
     5041 tagctaaagg aagcatcgaa agtatgcata atcttcctgt aaatctagca ggtgccagag
     5101 ttcctggcgg agtaaatggt agcaaagcag cggtgcatga agttccagaa tttacagggg
     5161 gagttaatgg tacagagcca gctgttcatg aaatcgcaga gtataaggga tctgattcgc
     5221 ttgtaactct tactacaaaa gaagattata cttacaaagc tcctcttgct cagcaggcac
     5281 ttcctgaaac aggaaacaag gagagtgacc tcctagcttc actaggacta acagctttct
     5341 tccttggtct gtttacgcta gggaaaaaga gagaacaata agagaagaat tctaaacatt
     5401 tgattttgta aaaatagaag gagatagcag gtttttaagc ctgctatctt tttttgatga
     5461 cattcaggct gatacgaaat cataagaggt ctgaaactac tttcagagta gtctgttcta
     5521 taaa
//
LOCUS       DAVKUR010000085         5392 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKUR010000085 DAVKUR010000000
VERSION     DAVKUR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.085"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..785
                     /locus_tag="VW749_002003"
     CDS             <1..785
                     /locus_tag="VW749_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0175975.1"
                     /translation="RIEDVFNTKSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVL
                     KGINVTIKKGETVAIVGESGSGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRK
                     IFGAVLQNSTLSYGTLRENLTFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEE
                     GNNFSGGQQQMILLARCLLSKPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAH
                     RLDTIKSADKILVMHNGEIVEIGTHRELLELGGIYKQLYSNN"
     gene            809..2547
                     /locus_tag="VW749_002004"
                     /pseudo
     CDS             809..2547
                     /locus_tag="VW749_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            2598..3365
                     /locus_tag="VW749_002005"
     CDS             2598..3365
                     /locus_tag="VW749_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0175976.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            3367..3999
                     /locus_tag="VW749_002006"
     CDS             3367..3999
                     /locus_tag="VW749_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0175977.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4945..5358)
                     /gene="ndk"
                     /locus_tag="VW749_002007"
     CDS             complement(4945..5358)
                     /gene="ndk"
                     /locus_tag="VW749_002007"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0175978.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
BASE COUNT         1876 a          798 c         1015 g         1703 t
ORIGIN      
        1 taagaataga ggatgtgttt aatactaaat ccgaattaat tccagaaaga gtcagtcaag
       61 atataaaatt tgataaaaaa atagaattaa aagatatttg gtataaatat ggattatttg
      121 atgattatgt tttgaaagga ataaatgtta ctattaaaaa aggagaaact gttgctattg
      181 ttggagaatc aggttcaggt aagagtacat tagctaaaat tttattaggt ttattagaac
      241 ctaatattgg ttcaatagaa gttgatggag tagaaaaaga agaaattggt caaacattgt
      301 atagaaagat ttttggagca gtgttacaaa attcaaccct aagttatggt accttaagag
      361 agaatttgac atttggacac tttgtttcag atgaagaatt aatgacaaat ctaaattcaa
      421 ttggtcttag caatgtagtt aaatctttac ctcttggatt agagacaatc atcgctgaag
      481 aaggtaataa cttttctgga gggcagcagc aaatgatact tttagctcgt tgtcttttgt
      541 cgaaaccttc ggtagttgtt ttggacgaag caacaagtag tttagataat ttatctcaac
      601 aaattacaac ttcttactta agtgaaatcg gtaccactaa gattttaatt gcccatcgac
      661 tagatactat caagtctgca gataagatct tagtaatgca taatggtgaa attgtagaga
      721 ttgggaccca tagagaactt cttgaactag gaggcattta taagcaattg tattcaaata
      781 attagttttt gattaaaagg gtaaatttat gaagattatg aaaaaaaaat attggacttt
      841 agcgatatta ttcttttgtt tgttcaataa ttctgttact gctcaagaaa tacctaaaaa
      901 tcttgatggc aatataactc acactcagac tagcgaaagt ttttctgaat ctgatgaaaa
      961 acaggttgac tattctaata aaaatcaaga agaagtagac caaaataaat ttcgtattca
     1021 aatcgataag acagaattat ttgtaacaac agataaacat ttagaaaaaa actgttgtaa
     1081 attggaactt gaaccacaaa taaataacga tattgttaac tctgaaagta ataatttact
     1141 aggcgaagat aatttagata ataaaattaa ggaaaatgtt tctcatctag ataatagagg
     1201 aggaaatata gagcatgaca aagataactt agaatcgtcg attgtaagaa aatatgaatg
     1261 ggatatagat aaagttactg gtggaggcga aagttataaa ttatattcta aaagtaattc
     1321 taaagtttca attgctattt tagattcagg agtcgattta caaaatactg gattactgaa
     1381 aaatctttca aatcactcaa aaaactatgt ccccaataaa ggatatttag gaaaagagga
     1441 gggagaggaa ggaataatat cagatattca agatagatta ggtcatggta cggctgttgt
     1501 agctcaaatt gtaggggatg acaatattaa tggagtaaat cctcacgtta atattaacgt
     1561 ctatagaata tttggtaagt cgtcagctag tccagattgg attgtaaaag caatttttga
     1621 tgctgtagat gatggcaatg atattatcaa tcttagtact ggacaatatt taatgattga
     1681 tggagaatat gaggacggaa caaatgattt tgaaacattt ttgaagtata aaaaggctat
     1741 tgattacgcg aatcaaaaag gagtaattat agtagctgca ttagggaatg actccctaaa
     1801 tgtatcaaat cagtcagatt tattgaaact tattagttca cgcaaaaaag taagaaaacc
     1861 aggattagta gttgatgttc caagttattt ctcatctaca atttcggtcg gaggcataga
     1921 tcgcttaggt aatttatcag attttagcaa taaaggggat tctgatgcaa tatatgcgcc
     1981 tgcaggctca acattatctc tttcagaatt aggacttaat aactttatta atgcagaaaa
     2041 atataaagaa gattggattt tttcggcaac actaggagga tatacgtatc tttatggaaa
     2101 ctcatttgct gctcctaaag tttctggtgc gattgcaatg attattgata aatacaaatt
     2161 aaaagatcag ccctataatt atatgtttgt aaaaaaattc tggaagaaac attaccagta
     2221 aaaaatggta taaaagtgtt aaatatacca aacgtattga gatatgattt gaatatgtta
     2281 caattagaat ataaaaatga acaaagttgg gatagtttca tagataatgt taatttaatt
     2341 gagttggaag agagaattca aactactatt ggaattaaac aaataaacac acacaatatt
     2401 attactattg cccgagaagg gtactctcaa aattatttac ctaacacttc agaaaataca
     2461 tataattcat tacaagtcag tttagttgga gtattactac tttttataag tatggtaaat
     2521 attttatggg ctaaaaaaag taaatgaaaa taaaatttgg agccctctga aaaagtaagt
     2581 cctacagttc aactaaaatg agtcaaaaga tgaatcacct tgatgtaggg gagtttgtct
     2641 tattgctgcc tgaacacctc cgttcagagg aagaacatta taaatctgtt tttgaagacg
     2701 acttaaccag tcgcatatct agtcaagatg aacgacagca aatgactgct acggtaggtt
     2761 atttagaatc aggtcaggat cgttttgtgt ataatacgac ccctatttct taccagcagt
     2821 ttttgaaaga tccaatcatc attgttataa caccccaatc aactggtcca cagtccattt
     2881 tgttttggat agacgcagta cagaactacg ttctctttaa tcaattgtct gatgcccagg
     2941 agcttatcca gagacaaggc attgaaaatt gggtctcaga aatgcaaaca ggttaccaca
     3001 actacatcac attattggat aatatccaga gggaacgttg ggtaatgcta gcaggagctg
     3061 tgcttgggat tgcaacttca atcttgttgt ttaacactat gaataggctc tactttgaag
     3121 aatttagacg tgccattttt atcaaacgca ttgcaggtct caggttctta gaaatccatc
     3181 gcacttatct ctttgctcaa ctgggtgtgt ttttactggg atttgttgcg agtgtatttc
     3241 ttcaggtaga gataggagtt gctttcttag tcttgttact ctttactggt ctatctcttt
     3301 tacagttaca tgtccaaatg cagaaagaaa acaagatgtc catgcttgtt ttgaagggag
     3361 gttaatatga ttgaacttaa acaggtgagt aaatcttttg gagaacgaga gttattttcg
     3421 aatctttcaa tgacatttga ggctggaaaa gtctatgcct taattggttc aagtggtagc
     3481 ggaaaaacaa ccttgatgaa catgattggg aaattagaac cttatgatgg gacgattttt
     3541 taccgaggta aagacttggc caattataaa tcaagtgatt ttttccgtca cgaattgggc
     3601 tacctcttcc agaactttgg cttaattgaa aaccaaagta ttgaagaaaa ccttaagcta
     3661 ggtctcattg gtcaaaagtt gagtcggtcg gaacagcggt tgaggcagaa gcaggcttta
     3721 gaacaggtcg gcctggttta tcttgaccta gataagcgca tctttgagtt atcgggcgga
     3781 gaatcgcaac gggttgcctt ggcaaaaatt atcttaaaga atccaccctt tattctggca
     3841 gatgagccaa cagcttcaat agacccagca acctctcagt tgattatgga gattttgcta
     3901 tctcttcgag atgataatag gctaatcatt atcgcaacac ataatccggc aatttgggag
     3961 atggctgatg aagtgttcac gatggatcat ctgaaataaa aatccttgtt tttaattgca
     4021 cgatgagtta ctgaaatatt atcatgaatc aagaattgga gttaatttag aattgtactt
     4081 aatttagaat tgtactttat taatattgag gtaacttttt cttgataaag gaagaaataa
     4141 tggagaggaa gttagaatga aaaaattcga caattatatt attgagaagc cttgcgattc
     4201 taattcagat aaactgcaaa aaatcttaat aattgaaagt ttggtagatg atattttgca
     4261 attttctctc agaatcaata atagtgtagg agagattttc ctcctacaac cgttttaaaa
     4321 gaaaactatc tttattccat gttattttga ggaagatatt gtgaaagtca aagatgatga
     4381 taaagttgag tggaatttgt tagaatttca aaaatttaga gcatttttgg cttagtaatc
     4441 tgtgttgaag gctcaaaacc tatggtaaaa aagtagcttt gaaaacgtat tgcctccaaa
     4501 gatttagtta aataatgatt taacacaaaa agaaattatt gaagttctgg aaagatgttg
     4561 tttcagtatt gagaaaaggt gggaaaaact tgcgattttc acagagaaag gaagaaaaag
     4621 tatagaaata tagtcaattg aaacaagaac aggataaaag aaccttttgt gccatatttt
     4681 tctcctttcg ctttacaatt ggattgaaca cctttattgt atcgcgtatg gagttttttt
     4741 ggtataacct tcgacgcaca cccgcatagc gggtgttttt tttgtctcgc acctaacgga
     4801 gcgagacaaa ctaatagtca cttaatcaaa aaacgcacca tatcaaaaac taaaaagttt
     4861 gatatcatgc gtcatgtctt aaactaattg actatacttt ctattcaaat gagcttttaa
     4921 ccaattgatt gagccaatcc actcttaaaa ccaaagagca atttctcgct tagctgactc
     4981 ttctgaatct gaaccatgta caacattttg gataatctca ttttctccag cagcttttgc
     5041 aaaatcacct cgaatagtgc ctggtaaagc ttcttctgga cgagttgcac ccatcatggt
     5101 ccgccaagtt tcgattactt tgggaccaga aatgacaccc acaagaactg gacctgaagt
     5161 catgaattca cgaatcggtg ggtaaaaact ctgaccaacc aagtcctgat agtgctggtc
     5221 aatcaactct tctgaaacct gtgaacgaaa ctccaatttt tcgattgtaa atccacgttg
     5281 ttcgatgcgc tttaacactt cacccactag ccctcttttt acaccatctg gtttgatgat
     5341 aaagaatgtt tgttccatac ccgtctcctt tgtcagcttc tttcttttat tt
//
LOCUS       DAVKUR010000086         4973 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKUR010000086 DAVKUR010000000
VERSION     DAVKUR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.086"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            277..1822
                     /locus_tag="VW749_002008"
     rRNA            277..1822
                     /locus_tag="VW749_002008"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1874..1946
                     /locus_tag="VW749_002009"
     tRNA            1874..1946
                     /locus_tag="VW749_002009"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1907..1909,aa:Ala,seq:tgc)
     gene            2071..4972
                     /locus_tag="VW749_002010"
     rRNA            2071..4972
                     /locus_tag="VW749_002010"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1405 a         1009 c         1462 g         1097 t
ORIGIN      
        1 acgggttcga atcccgtacg gactatggta tgttgcggtt ggaacacttg atgaaaaaaa
       61 gtttaaaaaa acttaaaaat cttcaaaaaa gtgttgacaa gcgaaagcag ttgtgatata
      121 ctaatatagt tgtcgcttga gagaagcaag tgacaaagac ctttgaaaac tgaacaagac
      181 gaaccaatgt gcagggcgct acaacataag ttgtagtact gaacaatgaa aaaacaataa
      241 atctgtcagt gacagaaatg agtgagaact caaactttta atgagagttt gatcctggct
      301 caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag gaggagcttg
      361 cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct ggtagcgggg
      421 gataactatt ggaaacgata gctaataccg cataagagta gatgttgcat gacatttgct
      481 taaaaggtgc acttgcatca ctaccagatg gacctgcgtt gtattagcta gttggtgggg
      541 taagggctca ccaaggcgac gatacatagc cgacctgaga gggtgatcgg ccacactggg
      601 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggacg
      661 gaagtctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      721 gtaagagaag aacgagtgtg agagtggaaa gttcacactg tgacggtatc ttaccagaaa
      781 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      841 tttattgggc gtaaagcgag cgcaggcggt tagataagtc tgaagttaaa ggctgtggct
      901 taaccatagt aggctttgga aactgtttaa cttgagtgca agaggggaga gtggaattcc
      961 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
     1021 ggcttgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
     1081 tagtccacgc tgtaaacgat gagtgctagg tgttagaccc tttccggggt ttagtgccgt
     1141 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1201 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1261 cttaccaggt cttgacatcc ctctgaccgc tctagagata gagttttcct tcgggacaga
     1321 ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1381 caacgagcgc aacccctatt gttagttgcc atcatttagt tgggcactct agcgagactg
     1441 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1501 ggctacacac gtgctacaat ggctggtaca acgagtcgca agccggtgac ggcaagctaa
     1561 tctcttaaag ccagtctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1621 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1681 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg taaggagcca
     1741 gccgcctaag gtgggataga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag
     1801 gtgcggctgg atcacctcct ttctaaggat aaggaactgc gcattggtct tgtttagtct
     1861 tgagaggtct tgtggggcct tagctcagct gggagagcgc ctgctttgca cgcaggaggt
     1921 cagcggttcg atcccgctag gctccattgg tgagagatca ccaagtaatg cacattgaaa
     1981 attgaatatc tatatcaaat agtaacaaga aaataaaccg aaaacgctgt agtattaata
     2041 agagtttatg actgaaaggt cagaaaataa ggttaagtta ataagggcgc acggtggatg
     2101 ccttggcact aggagccgac gaaggacgtg acaaacgacg atatgccttg ggtagctgta
     2161 agtaagcgat gatccaggga tttccgaatg ggggaaccca acaggtagta cctgttaccc
     2221 acatctgtta aggatgtgag gaggaagacg cagtgaactg aaacatctaa gtagctgcag
     2281 gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga agggcaaacc
     2341 gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt atagaagaat
     2401 gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt ctttgtacct
     2461 agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg aggaccatct
     2521 cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg gaaaggtgaa
     2581 aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa caagttcgag
     2641 cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac gttatgatgc
     2701 gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg cgccttagta
     2761 tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg tgcggtaaga
     2821 cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg tgggtagcgg
     2881 agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt agggctagcg
     2941 tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca tcccggatta
     3001 ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga ctgcgagtgc
     3061 taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaataattg
     3121 ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta gaagcagcta
     3181 ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga aaatgtaccg
     3241 gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg agagcgttct
     3301 atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag aatgccggta
     3361 tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt ccaggggaag
     3421 gctcgtccgc cctgggttag tcgggaccta aggagagacc gaaaggtgta tccgatggac
     3481 aacaggttga tattcctgta ctagagtatg tagtgatgga gggacgcagt aggctaacta
     3541 aagcagacga ttggaagagt ctgtctaagc agtgaggtgt gaattgagtc aaatgcttaa
     3601 ttctataaca ttgagctgtg atggggagcg aagtttagta gcgaagttag tgacgtcaca
     3661 ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa ccgacacagg
     3721 tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac tcggcaaaat
     3781 gaccccgtaa cttcgggaga aggggtgctg actttaagtc agccgcagtg aataggccca
     3841 agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt atagggggtg
     3901 acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag gtatgaattg
     3961 aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa ttccttgtcg
     4021 ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc actgtctcaa cgagagactc
     4081 ggtgaaattt tagtacctgt gaagatgcag gttacccgcg acaggacgga aagaccccat
     4141 ggagctttac tgcagtttga tattgagtgt ctgtaccaca tgtacaggat aggtaggagt
     4201 ctaagagatc gggacgccag tttcgaagga gacgctgttg ggatactacc cttgtgttat
     4261 ggccactcta acccagatag gtgatcccta tcggagacag tgtctgacgg gcagtttgac
     4321 tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa ggttccctca gaatggttgg
     4381 aaatcattcg cagagtgtaa aggtataagg gagcttgact gcgagagcta caactcgagc
     4441 agggacgaaa gtcgggctta gtgatccggt ggttccgtat ggaagggcca tcgctcaacg
     4501 gataaaagct accctgggga taacaggctt atctccccca agagttcaca tcgacgggga
     4561 ggtttggcac ctcgatgtcg gctcgtcgca tcctggggct gtagtcggtc ccaagggttg
     4621 ggctgttcgc ccattaaagc ggcacgcgag ctgggttcag aacgtcgtga gacagttcgg
     4681 tccctatccg tcgcgggcgt aggaaatttg agaggatctg ctcctagtac gagaggacca
     4741 gagtggactt accgctggtg taccagttgt cttgccaaag gcatcgctgg gtagctatgt
     4801 agggaaggga taaacgctga aagcatctaa gtgtgaaacc cacctcaaga tgagatttcc
     4861 catgattata tatcagtaag agccctgaga gatgatcagg tagataggtt agaagtggaa
     4921 gtgtggcgac acatgtagcg gactaatact aatagctcga ggacttatcc aaa
//
LOCUS       DAVKUR010000087         4804 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKUR010000087 DAVKUR010000000
VERSION     DAVKUR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.087"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(352..1080)
                     /locus_tag="VW749_002011"
     CDS             complement(352..1080)
                     /locus_tag="VW749_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0175979.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1238..2647
                     /locus_tag="VW749_002012"
     CDS             1238..2647
                     /locus_tag="VW749_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0175980.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2665..3960
                     /locus_tag="VW749_002013"
     CDS             2665..3960
                     /locus_tag="VW749_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0175981.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3965..4273
                     /locus_tag="VW749_002014"
     CDS             3965..4273
                     /locus_tag="VW749_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0175982.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4270..4578
                     /locus_tag="VW749_002015"
     CDS             4270..4578
                     /locus_tag="VW749_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0175983.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1620 a          816 c          884 g         1484 t
ORIGIN      
        1 tgaaattcat ttctagcaat ttgttagaag tcacagtcta ctattctaac atcagtatac
       61 tatatgtgtt acaagaaaag actcaaaaac ttctcgtcag tgtaagaata tttgaaacac
      121 tatttaaaac taaataacta taagaagtag atcaggtgaa caatttcagt acctactcta
      181 taagctatac gaagatattt ttcaacatga tggataaaac gatcactctt ttaaagccat
      241 cttatttaga aaagagaaac catttaagca tagatgggac cttcttgccc tgttttaaat
      301 ttttcttaaa ctagagtctg taaaagattg gcttcatttt cacattttct cctaggagga
      361 atgtcgtaat gcaaaagaat taaattcaaa taaatcatag cgatgacgac taatcgagta
      421 ctcaaacgga gttccgttat ccaaataagc cacttgttct acttcaaata ccggttccgt
      481 tggaaggagc tgcaagtaat gttgctcatt ttctgaacta gaagaagctc gcaagatttt
      541 tgtagcactg gcaatatgca atcctaactt tccttcaatg taattgtaaa tcgatttttg
      601 taaaatatct tcagtaatac ctggaataac atcagtactc atataagttt gttccagaac
      661 ataaggttta ccgtcaataa tacgcagacg gtaaatatta taaactggac tctgcaaagc
      721 gacctgtagt ttttctgcta aaaattcatt tgcaaattct aatttgaagt gaataatcct
      781 cgagtcaatt gtagaatgag catcttcaga tatttttgtc agtccccgga tatctctttc
      841 tggaacgatt aattttcttt ttgagctgcc acgagagaga acaaaggttc cctgcccacg
      901 ttttctaaaa attaagccct cagaaactaa caagtctaaa gcttttttga tcgtcattcg
      961 actacaggca aactgtttag ctaatgtcat ttcatcaggc aattgttcgt tcatggtata
     1021 tttattacaa agaatctttt cacgaatctc attgtaaata aataaatatt ttgtactcat
     1081 ttaatctggt tctctctata atattctaat agtagtataa caaagttcaa gaaatgaggc
     1141 aaacacaaga tatgtatcaa caatttttaa aaatgtctag acaaatttta aaattatgct
     1201 atactttatg tatagaataa tagaaaggag gttgagcatg aaaaaaaagt tagtatttcc
     1261 taatctattt tggtggggag ctgcttctag cggacctcag acagaaggtc aatatggaaa
     1321 agtacatgaa aatgtgatgg actactggtt caaaacgcat ccagaagatt ttttcgataa
     1381 tgtcggacct cttgtagcca gtaacttttt tcatacttac accgaagatt tccacttgat
     1441 gaaggaaatt ggagttaatt ctttccgcac ttccatccaa tggagtcgac tcatcaagaa
     1501 tttagagaca ggtgagcctg atccaaaagg tattgctttc tacaatgcca tcattgaaga
     1561 agctaaaaag aaccagatgg atcttgtgat gaatttacat cattttgatt taccagtgga
     1621 acttcttcaa aaatacggtg gttgggaaag caaacatgta gtggagttat tcgtgaagtt
     1681 tgccaagact gctttcacat gctttggaga taaggttcat tactggacaa ctttcaatga
     1741 gccaatggtc attccagaag caggatactt atatgctttc cattatccaa atctaaaagg
     1801 aaagggaaaa gaggccgtac aagtcatcta taatctaaac cttgctagtg caaaagtgat
     1861 tcaactatat cgctcattag aacttgatgg aaagattggg attattttaa acttgacacc
     1921 tgcttatcca agaagtaatt ctccagaaga cttagaagca agtcgattta cagatgactt
     1981 ctttaacaaa gtcttcttga atccagctgt taaaggaact ttcccagaaa gattggtaaa
     2041 acagctagag agagatggcg tgttatggag tcataccgaa aaagagcttc aactgatgaa
     2101 atcaaatacg gttgattttc ttggagtaaa ctactaccat ccaaaacgtg ttcaagcaca
     2161 agcaaatcct gaagaatatc agacgccctg gatgccagac caatacttca aagagtatga
     2221 atggctggag cgtcgcatga atccatatcg tggttgggaa atttttccga aagccattta
     2281 tgatattgct atgattgtga aggaagaata tggtaatatc ccatggttta tcagtgaaaa
     2341 cggaatgggt gttgaaaacg aagcacggtt tatcgatgaa aatggagtta tcgatgacgt
     2401 gtatcgtatt gaattttatg aagaacattt aagatggcta cataaagcca ttgaagaggg
     2461 aagtcactgt tttggatacc acgcttggac cgcatttgat tgctggtctt ggaataatgc
     2521 atataagaat cgttacggat ttatctccgt tgatttagaa acgcaaaaga gaaccatcaa
     2581 gagctcagga agatggtatc gcaaagtaag tgacaataac ggttttgaag tagaaattga
     2641 ggagtaaaga gaggagatat tcatatgaaa aactcaaaat ttatagacca atttgccacc
     2701 tttgctggta aactagggaa ccaaattcat ttaaaaaccc taagagatgc attcgtaaca
     2761 gtaatgccat tatatatttt ggcaggttta atcgttcttt tgaacaacac ggtatttaag
     2821 tggattttcc aaggggatac attaacaaga ttccaatatt ggggaataac aattgcaaac
     2881 ggtactttaa gtatttcagg tatgattatt gctgtaatgg ttggttattt cttagctaaa
     2941 aacagagatt tcgaaaaccc gttagcagca tcaatgctat cattagtttc tttaattgtg
     3001 atgatgccaa atacagtttc tgtagttcct gacggagcaa aagatgcggt aaacatttca
     3061 ggtgttcttt cattcaacaa cacaggtaca ggcgcaatgt tcgccggggt tatcgtagcg
     3121 attattgcaa cagaattatt cattgaatta tcaaacgtta aagctttaca aatgaacctt
     3181 ggtgaaaata ttccaccagc tgttagtaga tcatttagcg tattacttcc agtcatgacc
     3241 gtcatctcct tatttggggt tgtttcagca ttattattca atataactgg aatgaactta
     3301 atctcaatca ttacaatctt tattcaagaa ccaattcgtc atattggtac aagcttaatc
     3361 ggggtcatta ttatttactc tttaggaaat atgttatggc tatttggtat tcaccaagca
     3421 gttatttaca gtgccatcct agaaccatta ctattaatta acattactga aaacatcact
     3481 gcagcaaata atggacaagc cattccacac atcatcaacc tatcacaaat acaaacattc
     3541 gctttaatgg gtggtagtgg atctacatta tgtttattaa tagcaacatt cttagtgagt
     3601 cgcaatgctg tctctaaaaa cgtggctaaa ttatcttttg gacctggtat cttcaatatc
     3661 aatgaaccag tattattcgg ttacccaatc gtttataaca tttcattagc tattccattt
     3721 atcacagttc cagtccttgg tattttaatc agctacttag caacagttac aggattcatg
     3781 agtcctgcat ttatacaagt tccttggact acaccagtat tcttaaatgc atggttagca
     3841 acagcagggg acgtgagagc agttctagtt caattcatca tctttgcact tggagttctt
     3901 ctatacattc catttatcaa agttaatgac aaagttgttg aacaagaaat ggaaggttaa
     3961 gattatgaaa caaattttat tagtatgtaa tgcgggaatg tcgacaagta tgcttgttaa
     4021 aaaaatgcaa caaagtgcga ctgaacgtgg gattgaaatt tctatccaag caaaatcaat
     4081 gacagaggcg aaaaagaata tccatgaagc agatgtcatt ctaattgggc cacaaattcg
     4141 ttatgagtta cttgctgtga aagaaattgc aggaaatatc cctgtagata ccattgatat
     4201 gcgggattac ggaatgatga atggagcaaa agttctggaa caagcacttg catggatagg
     4261 agaaataaga tgacagaaga aatggaatat atctgttttc agctcattgc caatagtgga
     4321 gcagccaaat catcctttat tgaagccatc caactagcta aggcaggaaa tttaaaagaa
     4381 gcgaaaatta aagttgaaga agcggaagac tccttagtag aagtgcacaa gattcactct
     4441 aatctcatac aaaaagaagc tactggagaa aaaataggat tctccttgct atttatgcat
     4501 gcagaagacc aaatggcttc aacggagatt attcagttgc tatctaaaga attcatcgat
     4561 ctctatcaaa ataaatagga acactgtcgt tcccatctgt ctttattaat gacggctaca
     4621 ttgtaggaac ctccaaaagt tggacaaaat gattgaaagg attggatcct gcattacaca
     4681 agatccaatc cttttctttt actctagttt ttataatatg ttgaatctag aatagtccac
     4741 tgtagtttct aaaaaattgc tggaaatgga tgttaagctc caatttattt gtttatatct
     4801 tatt
//
LOCUS       DAVKUR010000088         4251 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKUR010000088 DAVKUR010000000
VERSION     DAVKUR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.088"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            713..1705
                     /locus_tag="VW749_002016"
     CDS             713..1705
                     /locus_tag="VW749_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0175984.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VW749_002017"
     CDS             1707..2525
                     /locus_tag="VW749_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0175985.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VW749_002018"
     CDS             2527..3312
                     /locus_tag="VW749_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0175986.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3410..3628
                     /locus_tag="VW749_002019"
     CDS             3410..3628
                     /locus_tag="VW749_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0175987.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3613..3810
                     /locus_tag="VW749_002020"
     CDS             3613..3810
                     /locus_tag="VW749_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0175988.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1179 a          736 c          913 g         1423 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaactctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctttcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggttggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaaggaga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaatttct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa ggcagttgtc gctgagattt tgaaggattt
     3421 gccagaatgg tttggaatcc cagaaagcac acaaacctat atagaaggaa ccacgacact
     3481 gcaagtttgg accgcctatc aggagagtga tttgactgga tttgtaagct tatcctattc
     3541 gagtgaagat tgtgcagaga ttgattgtct cggcgtaaaa aagcttatca aggtagaaaa
     3601 attgggagcc aattgcttgc tactttagag agtgaagctc gtaaaaaagt tggttatctg
     3661 caggtcaaaa cagtggcaga agcttctaat aaagattatg atcgaacaaa tgacttttat
     3721 cgaggtcttg gctttaaaaa gttagagatt tttcctcaac tatggaatcc gcaaaatcct
     3781 tgtcagattt tgattaaaaa gcttgaataa tattacttga catctatttt ttattctcag
     3841 agtgctatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttccggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcttagaa
     4141 aatctcttca aaccacgtca acgccgcctt gccgtgcgta tggttactga cttcgtcagt
     4201 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttctat c
//
LOCUS       DAVKUR010000089         4053 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKUR010000089 DAVKUR010000000
VERSION     DAVKUR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.089"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            220..483
                     /locus_tag="VW749_002021"
     CDS             220..483
                     /locus_tag="VW749_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0175989.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            489..2222
                     /gene="ptsP"
                     /locus_tag="VW749_002022"
     CDS             489..2222
                     /gene="ptsP"
                     /locus_tag="VW749_002022"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0175990.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            2477..>4053
                     /locus_tag="VW749_002023"
     CDS             2477..>4053
                     /locus_tag="VW749_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0175991.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         1333 a          787 c          866 g         1067 t
ORIGIN      
        1 ttgtgaaata gcaatgatta tcctataaat tgtttttgaa gaaactatat cctgtgtttt
       61 gttatctagg atagaagatt ttcagcaagt tatctgaaag gaaattgaag gaaaatccag
      121 aaaatgcttg aaaaaaatcc tagaagatgg tataatacta aattgtaagg gttatcacat
      181 ataactcaaa aaaagaaaga acaaaaggag agtcaaacta tggcttctaa agatttccac
      241 gtagtggcag aaacaggtat tcacgcacgt ccagcaacat tgttggtaca aactgctagc
      301 aaatttgctt cagatatcac tcttgagtac aaaggtaaat cagttaacct taaatcaatt
      361 atgggtgtta tgagtcttgg tgttggtcaa ggtgctgacg taactatctc agctgaaggt
      421 gcagatgcag atgacgctat cgctgcaatc tcagaaacaa tggaaaaaga aggattggca
      481 taagggaaat gacagaaatg cttaaaggaa tcgcagcatc tgacggtgtt gcagttgcaa
      541 aagcatatct actcgttcag ccggatttgt catttgagac tattacagtc gaagatacaa
      601 acgcagaaga agctcgcctt gatgccgctc tacaggcatc acaagacgag ctttctgtta
      661 ttcgcgagaa agcagtaggt acgctcggtg aagaagcagc tcaagttttt gatgctcact
      721 taatggttct tgctgaccca gaaatgatca gccaaatcaa ggaaactatc cgtgcgaaga
      781 aagtgaatgc agaagcaggt ctgaaagaag ttacagatat gtttatcact atctttgaag
      841 gcatggaaga caacccatac atgcaagaac gcgcagcgga tatccgcgac gtgacaaaac
      901 gtgtattggc aaaccttctt ggtaaaaaat tgccaaaccc agcttctatc aatgaagaag
      961 tgattgtgat tgcgcatgac ttgactcctt cagatacagc tcaattggac aaaaactttg
     1021 taaaagcttt tgtaaccaac attggtggac gtacaagcca ctcagctatc atggcacgta
     1081 cacttgaaat tgctgctgta ttaggtacaa acaacatcac tgaaatcgtt aaagacggtg
     1141 acatccttgc tgttaacggg atcactggag aagtgattat caacccgaca gatgaacaag
     1201 cggcagaatt taaagcagct ggtgaagcct atgcgaaaca aaaagctgaa tgggcacttt
     1261 tgaaagatgc tcaaacagtg actgctgacg gtaaacactt cgagttggct gccaatattg
     1321 gtactccaaa agacgttgaa ggtgttaaca acaacggtgc agaagctgtt ggactttacc
     1381 gtacagagtt cttgtacatg gattctcaag acttcccaac tgaagatgag cagtatgaag
     1441 catacaaggc tgttcttgaa ggaatgaacg gtaaacctgt tgtcgttcgt acaatggata
     1501 tcggtggaga taaggaactt ccttacttcg atatgcctca cgaaatgaac ccattccttg
     1561 gattccgtgc tcttcgtatc tctatctctg agactggaga tgctatgttc cgcacacaaa
     1621 tccgtgctct tcttcgtgcg tctgttcacg gtcaattgcg tatcatgttc ccaatggttg
     1681 cgctcttgaa agaattccgt gcagcgaaag cagtctttga tgaagaaaaa gcaaaccttc
     1741 ttgctgaagg tgttgcagtt gcggataaca tccaagttgg tatcatgatc gagattcctg
     1801 cagcggctat gcttgcagac caatttgcta aagaagttga cttcttctca attggtacaa
     1861 acgacttgat ccaatataca atggcagcag accgtatgaa cgaacaagtt tcataccttt
     1921 accaaccata caacccatca atcctacgct tgattaacaa tgtgatcaaa gcagctcacg
     1981 ctgaaggtaa atgggctggt atgtgtggtg agatggctgg tgaccaacaa gctgttccac
     2041 ttcttgtcgg aatgggcttg gatgagttct ctatgtcagc aacatctgta cttcgtacac
     2101 gcagcttgat gaagaaactc gacacagcta agatggaaga gtacgcaaac cgtgccctta
     2161 cagaatgctc aacaatggaa gaagttcttg aacttcaaaa agaatacgtt aattttgatt
     2221 aatcgaaaag tccctgcaac tcagttacag ggactttttt tgatatttta aaaagaattt
     2281 tcaagaaaat ctttcttata aaaagtccaa ccttgaaaaa gtagtggtca gaacaaaaaa
     2341 tacttaaatg gttcataaaa ttcttgacaa gttggagatt taggagtaaa ctattaacca
     2401 gttaagtaat agagaggagt ttctgcaatt tagaaatgaa ttgcaactag aaatatcaaa
     2461 tagaaagaga gtttcgatga aaattaataa gaaatacctt gttggttctg cggcagcttt
     2521 gattttaagt gtttgttctt acgagttggg actgtatcaa gctagaacgg ttaaggaaaa
     2581 taatcgtgtt tcctatatag atggaaaaca agcgacgcaa aaaacggaga atttgactcc
     2641 tgatgaggtt agcaagcgtg aaggaatcaa tgctgagcaa atcgtcatca agataacaga
     2701 ccaaggctat gtcacttcac atggcgacca ctatcattat tacaatggta aggttcctta
     2761 tgatgcgatt ttcagtgaag aattactcat gaaagatcca aactataagc taaaagatga
     2821 ggatattgtt aatgaggtca agggtggata tgttatcaag gtagatggaa aatactatgt
     2881 ttaccttaag gatgctgccc acgcggataa cgtccgtaca aaagaggaaa tcaatcgaca
     2941 aaaacaagaa catagtcaac atcgtgaagg tgggactcca agaaacgatg gtgctgttgc
     3001 cttggcacgt tcgcaaggac gctatactac agatgatggt tatatcttta atgcttctga
     3061 tatcatagag gatactggtg atgcttatat cgttcctcat ggagatcatt accattacat
     3121 tcctaagaat gagttatcag ctagcgagtt agctgctgca gaagccttcc tatctggtcg
     3181 gggaaatctg tcaaattcaa gaacctatcg ccgacaaaat agcgataaca cttcaagaac
     3241 aaactggcta ccttctgtaa gcaatccagg aactacaaat actaacacaa gcaacaacag
     3301 caacactaac agtcaagcaa gtcaaagtaa tgacattgat agtctcttga aacagctcta
     3361 caaactgcct ttgagtcaac gccatgtaga atctgatggc cttgttttcg acccagcgca
     3421 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     3481 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     3541 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aatcgactcc
     3601 ggaacctagt ccaagtctgc aacctgcacc aaatcctcaa ccagctccaa gcaatccaat
     3661 tgatgagaaa ttggtcaaag aagctgttcg aaaagtaggc gatggttatg tctttgagga
     3721 gaatggagtt tctcgttata tcccagccaa ggatctttca gcagaaacag cagcaggcat
     3781 tgatagcaaa ctggccaagc aggaaagttt atcgcataag ctaggagcta agaaaactga
     3841 cctcccatct agtgatagag aattttacaa taagacttat gacttactag caagaattca
     3901 ccaagattta cttgataata aaggtcgaca agttgatttt gaggctttgg ataacctgtt
     3961 ggaacgactc aaggatgtct caagtgataa agtcaagtta gtggatgata ttcttgcctt
     4021 cttagctccg attcgtcatc cagaacgttt agg
//
LOCUS       DAVKUR010000090         4014 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKUR010000090 DAVKUR010000000
VERSION     DAVKUR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.090"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(149..1210)
                     /gene="dinB"
                     /locus_tag="VW749_002024"
     CDS             complement(149..1210)
                     /gene="dinB"
                     /locus_tag="VW749_002024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0175992.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1559..3883
                     /gene="pflB"
                     /locus_tag="VW749_002025"
     CDS             1559..3883
                     /gene="pflB"
                     /locus_tag="VW749_002025"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0175993.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         1210 a          846 c          777 g         1181 t
ORIGIN      
        1 aagaaaaacc ttgaaggggc aactcttcaa ggttttatac tcttagaaaa tctcttcaaa
       61 ccgcgtcagc tttatctgca acctcaaaac agtgttttga gcagcctgcg gctagcttcc
      121 tagtttgctc tttgattttc attgagcttt aaaatccagt cagggtaatc cccaataggc
      181 ggacacctct ttctttctcg cttaattctt catagagttg cagggctatt tggcttatct
      241 gactagcatc ttgtgttttt tgagcaagac tttttcgttt ggtaagagtt gaaaagtcct
      301 cgtagcggat tttcaaaatg acaatttttc cagctttttc ttgttgatgt agattgagag
      361 cgactttttc tgatagaaga gtcagctctt ttttgatatc ttcctcagca aggagaatct
      421 tcccgtaggt tttctccttg ccgattgatt tacggatgcg attggatttg actggagagt
      481 tgtgaatgcc acgagccttt cgatacagat catagcctag tctaccaaaa cggtctatta
      541 gggttacctc aggaacttca agtaaatcag caccagtaaa aacgcccatt tgatgaagac
      601 gttctactgt cttttttcct actccatgaa atttggaaat atccatttgt ttgagaaaat
      661 cctcagcctg ttcaggtaga atcactgtca aaccatgtgg tttttgataa tcactcgcca
      721 ttttagctaa gaatttgttg taagaaacgc ctgcggaagc agttagatgg agttcttgcc
      781 agatatcttt ttgaatgagg cgagcaattt tgaccgctga cttgataccg agtttatttt
      841 ctgtcacatc caaataggct tcgtcaatgc tcatgggttc aatcaaatct gtatagcgct
      901 taaaaatagc tcgaatctgg agtcccacag acttgtattt ctcataattc cctgagataa
      961 agacagcctg gggacaacgt tcataagctt ccttggaact catggcagaa tggacaccaa
     1021 aagctcttgc ctcataacta caggtagaaa cgactccccg tccacctgtt tgccgagggt
     1081 cgcttccaat aatgacaggt tttcctctga gtttaggatt atccctgatt tccactgcag
     1141 caaaaaaggc atccatgtca atatggatga tttttcttga caaatcattt aacaaaggaa
     1201 aaatcaacat gcctagcacc tttttatact cttcgaaaat ctcttcaaac cacgtcagct
     1261 ctatctgcaa cctcaaaaca gtgttttgag caatctgcgg ctagcttcct agtttgcttt
     1321 tcgatttcca ttgagtgtta ctgcttattt tcttttatta tacccttttt tctgaaaaaa
     1381 agaaaaaagg actttatttt ttcaaaaata taatacagtt tgaaataaaa tatagactgt
     1441 tttagaaaag aaagtgtaaa aatagggaat tttcacttgt tgaaatcggt tactatatgg
     1501 tatacttgtc ttatgaatgt aacagatgac tgttactaga aaaaaagagg acattaatat
     1561 ggttgttaag acagttgttg aagcacaaga tatttttgac aaagcttggg aaggcttcaa
     1621 aggcgtagat tggaaagaaa aagcaagtgt atcacgattt gtacaagcta actacacacc
     1681 ttatgatgga gacgaaagct tccttgcagg accaacagag cgttcacttc acatcaagaa
     1741 aattgtagaa gaaactaaag cacactacga agaaactcgt ttcccaatgg acactcgtcc
     1801 aacatctatc gctgatatcc ctgctggatt tatcgacaaa gaaaatgaag ttatctttgg
     1861 tatccaaaat gatgaactct tcaaattgaa cttcatgcca aaaggtggta tccgtatggc
     1921 tgaaactact ttaaaagaaa atggatacga accagaccca gctgttcacg aaatcttcac
     1981 taaatatgta acaacagtta acgacggtat tttccgtgcc tacacttcaa atattcgtcg
     2041 cgctcgtcat gcacacactg taactggtct tccagatgca tactcacgcg gacgtatcat
     2101 cggtgtttac gcacgtcttg ctctttacgg tgcagactac ttgatgcaag aaaaagtaaa
     2161 cgactggaat gcaatcaaag aaatcgatga agaaacaatc cgtcttcgtg aagaagtaaa
     2221 ccttcaatac caagcattgc aacaagttgt tcgcctgggt gacctttacg gggttgatgt
     2281 tcgcaaacca gcgatgaacg tgaaagaagc aatccaatgg gttaacattg ctttcatggc
     2341 tgtctgccgt gtgattaacg gtgctgctac atctctaggt cgtgtaccaa tcgtattgga
     2401 catctttgca gaacgtgacc ttgctcgtgg tacatttact gaatcagaaa tccaagaatt
     2461 cgttgatgat ttcgttatga aacttcgtac agttaaattt gctcgtacaa aagcttatga
     2521 ccaattgtac tcaggtgacc caacctttat cacaacttct atggctggta tgggtaacga
     2581 cggtcgtcac cgtgttacta agatggacta ccgtttcttg aacacacttg acaacatcgg
     2641 taactcacca gaaccaaact tgacagttct ttggactgac aaattgccat acaacttccg
     2701 tcgctactgt atgcacatga gccacaaaca ctcttctatc caatacgaag gtgtaacaac
     2761 aatggctaaa gacggatatg gtgaaatgag ctgtatctca tgctgtgtgt ctccacttga
     2821 tccagaaaat gaagaacaac gccacaacat ccagtacttc ggtgctcgtg taaacgttct
     2881 taaagccctt cttactggtt tgaatggtgg ttacgacgat gttcacaaag actacaaagt
     2941 atttgatatc gaaccaatcc gtgacgaagt tcttgaattc gaatcagtta aagcgaactt
     3001 tgaaaaatct cttgactggt tgactgacac ttacgtagat gccttgaaca tcatccacta
     3061 catgactgat agatacaact acgaagctgt tcaaatggcc ttcttgccaa ctaaacaacg
     3121 tgccaacatg ggattcggta tctgtggatt tgctaacact gttgatacat tgtcagctat
     3181 caaatacgct acagttaaac caatccgtga cgaagatggc tacatctacg attacgaaac
     3241 aatcggtgac tacccacgct ggggtgaaga tgacccacgt tcaaacgaat tggcagaatg
     3301 gttgatcgaa gcttacacaa ctcgtctacg tagccacaaa ctatacaaag acgcagaagc
     3361 tacagtatca cttttgacaa tcacatctaa cgttgcttac tctaaacaaa ctggtaactc
     3421 accagttcac aaaggtgtat acctcaacga agatggttct gtgaacttgt ctaaacttga
     3481 attcttctca ccaggtgcta acccatctaa caaagctaaa ggtggttggt tgcaaaactt
     3541 gaactcactt tctagccttg actttagtta tgcagctgac ggtatctcat tgactacaca
     3601 agtatcacct cgcgctcttg gtaagactcg tgatgaacaa gttgataact tggtaacaat
     3661 ccttgatggt tacttcgaaa acggtggaca acacgttaac ttgaacgtta tggacttgaa
     3721 cgatgtttac gaaaaaatca tgtcaggcga agacgttatc gtacgtatct ctggatactg
     3781 tgtaaacact aaatacctca ctccagaaca aaaaactgaa ttgacacaac gtgtcttcca
     3841 cgaagttctt tcaatggatg acgccttgga tgcattgagc taatcaagtt cggctctttg
     3901 tcaactgcag tgggttgaag tcagctaagc tcgagaaagg acaaaattcg tcctttcttt
     3961 tttgatgttc agagcgataa aaatcctttt tttgaagttt tcaaagttcc gaaa
//
LOCUS       DAVKUR010000091         3960 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKUR010000091 DAVKUR010000000
VERSION     DAVKUR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.091"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..906)
                     /locus_tag="VW749_002026"
     CDS             complement(<1..906)
                     /locus_tag="VW749_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0175994.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEV"
     gene            complement(1024..1338)
                     /locus_tag="VW749_002027"
     CDS             complement(1024..1338)
                     /locus_tag="VW749_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0175995.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(1468..1706)
                     /locus_tag="VW749_002028"
                     /pseudo
     CDS             complement(1468..1706)
                     /locus_tag="VW749_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
     gene            complement(1758..3194)
                     /locus_tag="VW749_002029"
     CDS             complement(1758..3194)
                     /locus_tag="VW749_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0175996.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(3384..3722)
                     /locus_tag="VW749_002030"
     CDS             complement(3384..3722)
                     /locus_tag="VW749_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0175997.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT         1306 a          791 c          495 g         1368 t
ORIGIN      
        1 aacttcttca gaaatattct tctgattttt ttgacattgt tgactcttag ctaacaaatg
       61 caaagtaatg tagtctattt cctgaactgg aaattcctga tttgttactt ctcttacttt
      121 agaaagaatt ctttgggcaa cctttctctc tattgcatca tcagtcatct gacagtctat
      181 attttttatt tcaaatccgg attttaaacg aatcacagac aatgctatgt gaactactaa
      241 gttctgtagt acaaaatcag atagttttag gttggcctct tggcattcat ccaaaacaat
      301 tctagcaaat tcttctaatg gaacagtttg atcaaaaaag ttaaatttta catagcaatg
      361 tattgtttta aaaaattgat tctctaggaa ataatttatg ataaaacgtc gtttatcacg
      421 ttcctcgcct gagacataaa ctcctttatt cgccctactc tcaatggaca aattatactc
      481 tgataacatc actcgtatct ttctgaaatc atgagataat gttgaacggc taacgtaaag
      541 ttcatcagct aaatcatcaa aaagaactgg aacttgctca aataataatt tatttaagat
      601 aaatactaaa cgatcatcac cttttgaaac cgcagttttc gtatagtctt cttccagttc
      661 ataagtttgt ctaaactcct ggtaagcgcc ttgattctca aaaaatattt gatacccttg
      721 accttgtttt gaaatcaacc ggactccttg aataatcatt gtcttctcaa ttaatttcag
      781 tacattacgg acagttctat ctgaacagga taaatattct gccagttctt tgcttgtaac
      841 aaaacgttcc ttatttttta ttaaaaattg aaggatatct ttctctttaa tgtttaacac
      901 attcattccc tcctaaaacg tatgttttca tatattgaag catattatac acttaaatca
      961 atttatatca aactcaaaac aatttatctt aacttaaata tttattgaca tttcatgtgt
     1021 tcatcaaata ttctcaagaa tcaaattagc cattttttca attcccattg gaataggaat
     1081 ataggcttga ggaggtattt gtacaactgg ttttcctgct ttagaaccag cctcttcaaa
     1141 ttgcttaaag tacatttttg tttgagggct gacaagatac aaatcaaaag ctgctgctgc
     1201 gatagctttc cctccttcag tagcactaat agcatcaact acaatatctt tcccttttcc
     1261 ttttagaaac tctgttgttt tctgtgccat aagtgatgaa gacattcctg ctgcacaaat
     1321 aattaaagct tttgccataa tattttctcc ttttcttaaa tccaatcaaa gctgtgctaa
     1381 gttgacttat ctgttatcta tttttattat aaaataaagc gtttccaatg acaattccct
     1441 cattttccta aatgatatgg aaaaaaatta tttatacttc aatttataaa ataaaattat
     1501 tcctgagagt agaaatgaaa cactatttgc taaaatcaaa ggcaagtctc ctatacgaat
     1561 accatgagca agccacaatg caatatcaat aacttgcata acatacatac ctagagcaat
     1621 agatcctgtg tcctttgtct taactatacg aaaaacttgt ggtaaaaagc aaatgttgtt
     1681 aaaattgctg caatacttcc aatcatatgt catcccaata tgctaaacaa actgagaata
     1741 atctcagttt gtttatacta ttctactgat tcaccgttag atgaaataac ttccttatac
     1801 cagccaaaag attttttcgg ggaacgatta taacttccct tcccattgtc atctttatct
     1861 acataaataa aaccataacg tttccgcatt tcaccggtac cagctgaaac caaatcaata
     1921 catccccatg gagtataacc cattaaatca acaccatctt caactacagc ctttttcatt
     1981 tcacgaatat gggcacctag atattcaatt ctataatcat catgtaccat accatctgct
     2041 gcaacttgat ctatagctcc aaaaccattt tcaacaataa agagtggtaa gtgatagtgg
     2101 tctgtaaacc aatttaacgc ataacgtaaa ccttctggat caatttgcca ctcccattca
     2161 gaagccttaa cataattatt tttcactaaa tcttctgttt caagataatc aaaataagga
     2221 ttattttcac gatgagagtc tatagcaaag gacatatagt aactgaaacc aatgtaatct
     2281 acagtcccac caagtaaatc ttctttatcc tggtcagtaa aatcaactga aatacctttt
     2341 cgttcccaat acttgaaaat atgctcagga tatttaccta aaacatgcac atcagcaaaa
     2401 taataacgct tctgcatagc tttcattgcc attaagatat ccttaggatt gcaagtagct
     2461 ggataaattg gacacatcgc aatcatacaa cctatttgaa aatctggatt aatctcatga
     2521 ccaattttta cagctcgtgc agaagcaact agttcgtaat gtgctgcttg atacataatt
     2581 gcttctctat tatcaccttc ctcatataca atacctgagt tagtaaatgg tgcaaaatct
     2641 tcctgataat tcgcttgatt attgatttca ttgaaagtca tccaatattt aaccttatct
     2701 ttgtaacgtt taaatacgac ttctgcaaaa cgagcaaaga aatcaatcaa tttcctattt
     2761 ttccaaccac catattcggt cactaagtga taaggcattt caaaatgaga tagagtgatg
     2821 acaggttcaa taccattctt taagcattca tcaaaaagat tatcataaaa ctgtaatcct
     2881 tcttcattcg gctctaactc atcacctttt ggaaagatac gtgtccatgc aatagaggta
     2941 cggaagcact tgaatcccat ttcagcaaaa agtgctatgt cttctttata acgatgataa
     3001 aaatctatcg cctcatgatt tggataatat ttaccctcta aaactcccga agtaatttca
     3061 cgagctactc catgacgacc agcagtcata acatcagcaa cactaattcc tttgccacct
     3121 tcttgccatc cgccttcaag ttgatgagca gcaacagcac caccccataa aaatctatct
     3181 ttaaaagtag tcatcttttt tcctcctgac tttgatactc ttattataaa cctcaaacca
     3241 aaaaatgaaa acgtattctt tttccttatt gttaaggaaa gaagtaattt ttaatggaaa
     3301 tagaacaata tcttcttgta ttctcgtaat gatatcttta cgattttcaa tactttcaaa
     3361 ctacaaaaac tctcacaata attctaattc cctgtgtcta taaacgactt atcgctttct
     3421 ggcatcccag aatcatcttc tatataacgt tcaacttgca tctgcaagtg atattttttt
     3481 cttaaatcta agattttctg cattgtcttt gattgataat gtttatctaa agtttcttga
     3541 tttatccact gatcaataag gagaatagtt ccctcttttt caattggtaa aaaatattcg
     3601 tatttcaagt tacctttttg atttctaatt tcttcaacaa ggccactatc aagcatttct
     3661 cttgcaaact ttattgcact atctccatca cctttataat atacatgaat agtcaatgtc
     3721 atcttatatc ctccaaaatc atccttcaat tttaaaaaaa caagtttaga tgaggatcta
     3781 aacttgtttt ttatgaacta attatctaac gttttgccat tactttcaat cacttcttta
     3841 taccaataaa atgatttttt cttatagcga tttatagtca attgaaacaa gaacaagaca
     3901 aaagagcctc ataaaaggta tggcaacttg gtaatacctt tttgaggtgc tttttgatat
//
LOCUS       DAVKUR010000092         3613 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKUR010000092 DAVKUR010000000
VERSION     DAVKUR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.092"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..177
                     /locus_tag="VW749_002031"
     CDS             <1..177
                     /locus_tag="VW749_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0175998.1"
                     /translation="AEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDS
                     LLALLKESQPTPIQ"
     gene            387..3506
                     /gene="phtE"
                     /locus_tag="VW749_002032"
     CDS             387..3506
                     /gene="phtE"
                     /locus_tag="VW749_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0175999.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLKEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1349 a          588 c          696 g          980 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat tctagtatta gacaaaatgc tgtggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttgttaaaa gaaagtcaac cgactcctat acagtagtaa
      181 aatgaatgga gcatatttta tggagaagta acctttcgtg ttacttctct tttttagaaa
      241 aacgtaacag aaacttgaca aaagtaattt taaatagtaa actatttact ggttaattaa
      301 atggttaaat aaccggttta gaaaactatt taataaagta aaagaagttg agaaaaaact
      361 tcatcattta ttgaaatgag ggatttatga aattcagtaa aaaatatata gcagctggat
      421 cagctgttat cgtatccttg agtctatgtg cctatgcact aaaccagcat cgttcgcagg
      481 aaaataagga caataatcgt gtctcttatg tagatggcag ccagtcaagt cagaaaagtg
      541 aaaacttgac accagaccag attagccaga aagaaggaat tcaggccgag caaattgtaa
      601 tcaaaattac agatcagggc tatgtaacgt cacacggtga ccactatcat tactataatg
      661 ggaaagttcc ttatgatgcc ctctttagtg aagaactctt gatgaaggat ccaaactatc
      721 aacttaaaga cgctgatatt gtcaatgaag tcaagggtgg ttatatcatc aaggtcgatg
      781 gaaaatatta tgtctacctg aaagatgcag ctcatgctga taatgttcga actaaagatg
      841 aaatcaatcg tcaaaaacaa gaacatgtca aagataatga gaaggttaac tctaatgttg
      901 ctgtagcaag gtctcaggga cgatatacga caaatgatgg ttatgtcttt aatccagctg
      961 atattatcga agatacgggt aatgcttata tcgttcctca tggaggtcac tatcactaca
     1021 ttcccaaaag cgatttatct gctagtgaat tagcagcagc taaagcacat ctggctggaa
     1081 aaaatatgca accgagtcag ttaagctatt cttcaacagc tagtgacaat aacacgcaat
     1141 ctgtagcaaa aggatcaact agcaagccag caaataaatc tgaaaatctc cagagtcttt
     1201 tgaaggaact ctatgattca cctagcgccc aacgttacag tgaatcagat ggcctggtct
     1261 ttgaccctgc taagattatc agtcgtacac caaatggagt tgcgattccg catggcgacc
     1321 attaccactt tattccttac agcaagcttt ctgccttaga agaaaagatt gccagaatgg
     1381 tgcctatcag tggaactggt tctacagttt ctacaaatgc aaaacctaat gaagtagtgt
     1441 ctagtctagg cagtctttca agcaatcctt cttctttaac gacaagtaag gagctctctt
     1501 cagcatctga tggttatatt tttaatccaa aagatatcgt tgaagaaacg gctacagctt
     1561 atattgtaag acatggtgat catttccatt acattccaaa atcaaatcaa attgggcaac
     1621 cgactcttcc aaacaatagt ctagcaacac cttctccatc tcttccaatc aatccaggaa
     1681 cttcacatga gaaacatgaa gaagatggat acggatttga tgctaatcgt attatcgctg
     1741 aagatgaatc aggttttgtc atgagtcacg gagaccacaa tcattatttc ttcaagaagg
     1801 acttgacaga agagcaaatt aaggctgcgc aaaaacattt aaaggaagtt aaaactagtc
     1861 ataatggatt agattctttg tcatctcatg aacaggatta tccaagtaat gccaaagaaa
     1921 tgaaagattt agataaaaaa atcgaagaaa aaattgctgg cattatgaaa caatatggtg
     1981 tcaaacgtga aagtattgtc gtgaataaag aaaaaaatgc gattatttat ccgcatggag
     2041 atcaccatca tgcagatccg attgatgaac ataaaccggt tggaattggt cattctcaca
     2101 gtaactatga actgtttaaa cccgaagaag gagttgctaa aaaagaaggg aataaagttt
     2161 atactggaga agaattaacg aatgttgtta atttgttaaa aaatagtacg tttaataatc
     2221 aaaactttac tctagccaat ggtcaaaaac gcgtttcttt tagttttccg cctgaattgg
     2281 agaaaaaatt aggtatcaat atgctagtaa aattaataac accagatgga aaagtattgg
     2341 agaaagtatc tggtaaagta tttggagaag gagtagggaa tattgcaaac tttgaattag
     2401 atcaacctta tttaccagga caaacattta agtatactat cgcttcaaaa gattatccag
     2461 aagtaagtta tgatggtaca tttacagttc caacctcttt agcttacaaa atggccagtc
     2521 aaacgatttt ctatcctttc catgcagggg atacttattt aagagtgaac cctcaatttg
     2581 cagtgcctaa aggaactgat gctttagtca gagtgtttga tgaatttcat ggaaatgctt
     2641 atttagaaaa taactataaa gttggtgaaa tcaaattacc gattccgaaa ttaaaccaag
     2701 gaacaaccag aacggccgga aataaaattc ctgtaacctt catggcaaat gcttatttgg
     2761 acaatcaatc gacttatatt gtggaagtac ctatcttgga aaaagaaaat caaactgata
     2821 aaccaagtat tctaccacaa tttaaaagga ataaagcaca agaaaactca aaacttgatg
     2881 aaaaggtaga agaaccaaag actagtgaga aggtagaaaa agaaaaactt tctgaaactg
     2941 ggaatagtac tagtaattca acgttagaag aagttcctac agtggatcct gtacaagaaa
     3001 aagtagcaaa atttgctgaa agttatggga tgaagctaga aaatgtcttg tttaatatgg
     3061 acggaacaat tgaattatat ttaccatcgg gagaagtcat taaaaagaat atggcagatt
     3121 ttacaggaga agcacctcaa ggaaatggtg aaaataaacc atctgaaaat ggaaaagtat
     3181 ctactggaac agttgagaac caaccaacag aaaataaacc agcagattct ttaccagagg
     3241 caccaaacga aaaacctgta aaaccagaaa actcaacgga taatggaatg ttgaatccag
     3301 aagggaatgt ggggagtgac cctatgttag atccagcatt agaggaagct ccagcagtag
     3361 atcctgtaca agaaaaatta gaaaaattta cagctagtta cggattaggc ttagatagtg
     3421 ttatattcaa tatggatgga acgattgaat taagattgcc aagtggagaa gtgataaaaa
     3481 agaatttatc tgatctcata gcgtaaggaa tagcagtaga aaaagtctga atcaaaaatg
     3541 aagttctctc aaaagttaga aataaaactc tgactttggg agaatttcat tttattatta
     3601 atatataaaa ttt
//
LOCUS       DAVKUR010000093         3538 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKUR010000093 DAVKUR010000000
VERSION     DAVKUR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.093"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(234..845)
                     /gene="rpsD"
                     /locus_tag="VW749_002033"
     CDS             complement(234..845)
                     /gene="rpsD"
                     /locus_tag="VW749_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0176000.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1040..2092)
                     /locus_tag="VW749_002034"
     CDS             complement(1040..2092)
                     /locus_tag="VW749_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0176001.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2089..2787)
                     /locus_tag="VW749_002035"
     CDS             complement(2089..2787)
                     /locus_tag="VW749_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0176002.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            complement(2954..>3538)
                     /locus_tag="VW749_002036"
     CDS             complement(2954..>3538)
                     /locus_tag="VW749_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV0176003.1"
                     /translation="PWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQAL
                     IDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSN
                     SGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPN
                     TGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          977 a          790 c          684 g         1087 t
ORIGIN      
        1 gctcacaata agagagaact tttttacgaa aatctattga atatgccata aaagattata
       61 ccacattgtg tactattttt ggttcatttt actatatcac tttggactat atcggtctag
      121 ttatgtctca acgattatag ctggatacta agagaaatca aaaaagcact aagggagaac
      181 gtcccaaagt gcttaatatc aaggcctcaa agcctgtctt attcaataaa atattacaac
      241 atcttgttgt agaattcaac gacaagtgct tcgttgattt ctgggttgat ttcgtcgcgt
      301 tctggcaagc gagtcaatga accttccaac ttttcagcgt cgaatgatac gaatgctgga
      361 cgtccaagag tagcttctac tgcttcaagg attgctggaa ctttcaatga tttttcacga
      421 actgagatca cttgacctgg agttacgcgg tatgatggga tatcaacgcg tttcccgtca
      481 acaaggatgt gaccgtggtt tacgaattga cgagcttgac gacgagtagt cgcgagacca
      541 agacggtaaa caacattatc caaacgacgt tccaaaagaa gcataaagtt gaaacctagg
      601 attccacctt tgatttttgt agcttgtacg aacaagttac ggaattgttt ttcacctaca
      661 ccgtaagtga aacgaagttt ttgtttttca gccaattgca aaccatattc tgacaattta
      721 gaacggttgt ttggtccgtg ttgtcctggt acgtagttac gacgtgccaa ttctttacct
      781 gtacctgtaa gtgaaaggcc aaggcgacga gcttgtttcc aagatggtcc tgtataacgt
      841 gacatatgaa tgtcctcctg atataaataa tatttcggtg gaaatagtca cttagaaagc
      901 cctgattcgt gcagatgccc ttcgcctaaa cagccaaggt tacttgtcat aagacacctg
      961 ttgacgagct tcatgctttc ctgctgatat ttcacacaaa atccatttta ccatgaatag
     1021 ctggatttgt aaaggggttt taggctttat tttcactacc agagaggttg agaacgaggg
     1081 taaaggtact tcctagaccg tactggctgc tgactgtgat ttccccaccc aattgatggg
     1141 ccaattcacg cgcaatcgca agtcctaatc catgaccacc tgtcttcatg ttacgcgaag
     1201 tttcgacacg ataaaggcgt ttgaaaatat tttccaaatc ctctggggca atgccctgcc
     1261 cttcatcggt cacactgatt gaaagctggt ccttctccag cttagccacc acttccagct
     1321 tggttcctgg agcagaatat ttaaaagcgt tatcgaccag attcaccaag atacgagaaa
     1381 gcttagcata atctccctca atccgggcag actctgggat tacctgcaag tggacatctc
     1441 ttctctcctg ctcaatcaaa aactgaaatt cactcatgca ctcaattaag agcttgtcca
     1501 gaaaaatact gtctttactg gtagtttcca cctgatttct agctgtgttt agggtcaaaa
     1561 aattcaactc ctcaaccagt ttattgagcc tctccgtctg gcgtccaatg gttgctagat
     1621 aatgagcttg ctccgactcc ttgataatcc catccaaaat cccttctacc gtcgcttgga
     1681 tcgaagtgat aggggtctta atatcatgcg acaactgggc aatcatcaag cccttttctc
     1741 gttcgctttc ttccaaggaa tcaaagctta cctgcaaatc atgggacatc tcattaaaag
     1801 tttgccctaa ttgctgaaat tctacaggac cttgaacctc caaatttgaa ggaaaatcct
     1861 tggccgctac ccgcttggca tgctccttga gtttgcccaa cgacgtaaag actggcaata
     1921 ggagaaagag actaatccca gcaccgacaa ggctggcaac gatggtcatc ccaagcaaaa
     1981 agtaaatctc gcctttcgca atcagcattt tttgaacagc ccaaaaaaca accaaaatgg
     2041 ttaagagggt tgaaataata tatccaacca aaatataact ttttagtttc atatttgtcc
     2101 tctcggtttc tctatcttat atcccaaccc ccaaactgtc ttaatagtgg gagtttggtc
     2161 actactatat tttgccagct cctgtcgaag agcatggata tgcacattca aggtattggt
     2221 gtcatccacg tagtcttctt tccagatctt ttcatagagg tctgtcttgg agaaaactcg
     2281 ctctggattg ctagctaaaa tccacagcaa ttcaaatgat ttaacagtta aatccagcat
     2341 ttcttctcct atttgaactt catgactact atgattcatt tttagattgc caagggaaat
     2401 cagctctgtt tcgcccccac gatgaaggcg gcgcaaaata ttgtggacac gcaaaaccag
     2461 ctcacgtggg ctaaaaggct tagcaataaa atcatctgct cccaagctca ggccgtaaat
     2521 cttgtcctgt tcactggtct tagcagtaat aaataggaaa ggctgctctg gtgataagta
     2581 ttgaacctca ctgattaaat cataaccatc catccgaggc atcatgacat ctgtgataat
     2641 caaatcaatc ggttttttct tgaacagctc tagcgcttcc agtccatcat gggctaccaa
     2701 gacctgataa cctgcctgaa ttaagtatct ctgatgaata tctgtgattt ctacctcgtc
     2761 gtcaacgagt aaaattgtct ttcccatctg tctctccttt gataaaaaca gtgctatact
     2821 gctttaagta taacactatt tttattgttt tacgatgatt ttaatctgct attgaaagaa
     2881 agtcctgatt gctgattgag ttgttaaact aatcttagtc agcccactat ccatcattta
     2941 tttccttagc tgattagttt tcttcttttt tgtttttcaa acctagacca ccgagtaaac
     3001 ctgcaagcgc aagcccaagg aaaccaatac ttgccattga tgtttgagtc tcaccagtat
     3061 ttggtagcat agctttatcc tctgacatca tcgtatcaga catcttgtta gcagaagcag
     3121 ccatgttttc acctgccatc gtgttggtag aacttgtcat ggtgtcagca ggcatgctat
     3181 ctgtagtacc tgtagcatga ttgtgattca tcggagtcac gccagaacca gagttagaag
     3241 gtgataatga accatttgct gtgtctgatg tttctttaac atttatctta atagtgactt
     3301 ttttagttgc tacgatgttg tccaaatctg gtttaccgtc tttgttacca tagacattga
     3361 ctgtagcgct gtaagtttga gtaccatttg ctcggaactg gtcaatgagc gcttgttttt
     3421 ctttgccagc tacatttccg tccaaggcta attgatagaa gtattgacct ttggtcttca
     3481 cgttttcacc tagtggagat agagctgggt ttttagcgtc gccgttatct gaccatgg
//
LOCUS       DAVKUR010000094         3514 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKUR010000094 DAVKUR010000000
VERSION     DAVKUR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.094"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            24..1247
                     /locus_tag="VW749_002037"
     CDS             24..1247
                     /locus_tag="VW749_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0176004.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPSVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTATKYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKKFDFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2258..2542
                     /locus_tag="VW749_002038"
     CDS             2258..2542
                     /locus_tag="VW749_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176005.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDIEKL
                     LDSKELTHFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            2535..3092
                     /locus_tag="VW749_002039"
     CDS             2535..3092
                     /locus_tag="VW749_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEV0176006.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT         1301 a          618 c          522 g         1073 t
ORIGIN      
        1 aaataaacca aaggaggaaa caaatgatta caaaacaatc agccttttta caaaatagag
       61 ccactatact ggaatttcta tatcgaaatc cagcaacatc ccgtacagat attgttaatg
      121 aaacaggact tactccagca acaacgacta acatcataaa agagctaagc gaacaatccc
      181 tcatatacga aactggtgat gaatttagcg agttttccgg atctggaaga cgtagaaaaa
      241 ctatttctat tacagataat atcccatctg ttgttggagg tattgaaata aacgtcttag
      301 gtatctttct cagtctatgt gacttacaag ggaaaactct tttcgagaca gaaattttga
      361 atgaagatta tcctatttca gaaatcaatt ccaccattac caatatgata aaaacagcta
      421 caaagtatgt ccctttggag acaaaattac ttggatttgg cttatcaata cctggacatt
      481 ataacaaaga ctccggaagc atcattacaa acaaccccat atgggaatca tttaatttat
      541 taaatgtaat taaaaaattc gatttccctt ttattgtaaa aaataatatc gattgtatgg
      601 ctataggaca ataccttttt aacccacaca atacccccga taactttatt ttcctacacg
      661 ctggattagg tatttacact tcctttttca caaaagaaaa aataggagcc tctaaaaatc
      721 cttatatcgg agaaattgga cacaccattg tcgaattaaa tgggcaatat tgtgaatgcg
      781 gaaaaaaagg ttgtttacaa acatatattt cggatgcttg gttaatcaaa catgcccaat
      841 tattatttaa aaattctcaa ctaactgtac taaaaagcct tgtaaagact gaaaaagaca
      901 ttcatttaga taccctttta acagcttaca acttaggcga ctctgcttta cgccaacaaa
      961 ttgataaagg agtcaattta ttggccactt ctattgcaaa tcttctcctc atcaatcctg
     1021 ctgataaaat ctatatcaac agtcaattgc ttaattatca acctttcact catgaagtca
     1081 gggataaaat ccaagatcag ctccacttcg ttccctttac tcgtaatata gaaattgaaa
     1141 ttttacctta caacaaacat cgtggaagta taggagcttg tgcattagct atcgttgctt
     1201 ttttcataga gcatagcaat gtattacaag atattatttc accttaatat attagaaatc
     1261 tatagacctg tttaaatcaa ctataacctg tagtaaatat ctcgtattta gacaatatga
     1321 aaacaagacg acttccatat aggaaaccgc cttctcgcta tgctgcatga aactgtaaaa
     1381 atagatgaaa gtgatagcgg tagtcaaatc aagaggcatc ataactctaa aaagtcacaa
     1441 tatataagtt catcctcaga aaaatatcat tctaattatt gaaatgccta catgaaaaga
     1501 aacgttaaat gctcataaaa caaggaatac aggtatcaaa actgtgacaa aacaagtccc
     1561 taaatttact aaagacacta ctcaacttta cacctgtaaa tggttgttgt ataataaagt
     1621 tacaaagatg tacgaccaca ctgttgtaaa tcatagtgtt cgcgaatata ttactgatag
     1681 catttctaca aatacaagta aagggattgg atgagattca aacgaaatat gtcagtgttt
     1741 tggcattcct agccttcata tcatttaaag aattgtatag ataaaatttt tcccaataca
     1801 gacactcgta acaactgctt catttttcta ccaacatatt taggaacagg ataagataca
     1861 agaggatcaa tccataaatc agttctatac caatctaaga caaataagct aaaaaaacga
     1921 ttgataataa gcaaatagat tccaaatttt ctctatctgc tcattttaat aaacaatact
     1981 agtgtaacta tccttccagt cagaagcttg tcaaatcaca ccgaaaattc ttctaaaatt
     2041 tatctcgtta ggcaatcaag caaaaactca acgatagtac aaacattatc atacaggatt
     2101 gacttcctaa attatatact ttagtaaggt ttttggataa gaaaaaaggt tcattttaca
     2161 tttctaaaca ctcttttcta atacgagata attaaaaaaa ctacattttt aaatataaac
     2221 tacaataaaa taaactaaat gccataggag aaagacaatg gattggtacg attatatgat
     2281 acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt tgcgaaaagt
     2341 tatttttgaa gactattctt atttaacaaa ccaagatata gaaaagttgc tagactccaa
     2401 agaactaacc cattttcaaa aaattagctt gaagtatgcc tttcaagagc atactccaac
     2461 tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc aaaaattgat
     2521 ggagaaatac aagcatggat aaaatgaaac cggtcttcca agcactaaat aaggaattaa
     2581 ttcaggaaaa tctgacttta acaattatct gtgtcggtgg ttatgtctta gaatatcatg
     2641 gtttgcgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     2701 ttattgctcg tgtaggaaaa cagtttaatc ttaacaccca cgaagagtta tggctcaaca
     2761 atcatgttgc aaatatgaac aaacaacctc ccttaagttt atgcgaatcc ttgtactcat
     2821 ttgagaatct gaccgtttta gtagtcccta ttgagtatgt gttaggaatg aagatgatga
     2881 gtatcagaga gcaggatttg aaagatattg gtgcaattat taaatacaaa aactttcatt
     2941 caccattcga tacctttaaa tatttaaaag acatgggatt tgatactatt gacctctctg
     3001 ttctattaga aggttttagt tatgcttatg gtatggattg gttagaaaaa ttttttaaag
     3061 aaaatcaaga taaacttcgc gaattttatt aacagtatca aacaagatga ttgtcaatta
     3121 gccagtcgtc ttgtttttat gatgaaatga aataaaatcg gaacaaatca cttagagaat
     3181 tccagtcaat ttctagcact gtttgagacg tttcagcgga ctatagcaaa atgaaataag
     3241 aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta gaagtaaagg
     3301 tgtactattc tactttcaat ctattatatt tcagattcgg tccactattc cttcccaaaa
     3361 acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa ccctcagtcg
     3421 tttgaccgag ggttcctttt tattattcaa gaacttgagg ctctataata tttgtagtgg
     3481 gtaaatcccc tatggatatt atggagccta tttt
//
LOCUS       DAVKUR010000095         3346 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKUR010000095 DAVKUR010000000
VERSION     DAVKUR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.095"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            72..524
                     /locus_tag="VW749_002040"
                     /pseudo
     CDS             72..524
                     /locus_tag="VW749_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            629..977
                     /locus_tag="VW749_002041"
                     /pseudo
     CDS             629..977
                     /locus_tag="VW749_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(1248..1469)
                     /locus_tag="VW749_002042"
     CDS             complement(1248..1469)
                     /locus_tag="VW749_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176007.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            1434..2063
                     /locus_tag="VW749_002043"
     CDS             1434..2063
                     /locus_tag="VW749_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176008.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(2099..3322)
                     /gene="pepT"
                     /locus_tag="VW749_002044"
     CDS             complement(2099..3322)
                     /gene="pepT"
                     /locus_tag="VW749_002044"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0176009.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
BASE COUNT         1110 a          647 c          646 g          943 t
ORIGIN      
        1 ttgttatcct ttccttaagt ctgtgtgttt atgctctgaa ccaacatagc taacaggcca
       61 atacagataa aaatcgtgtt tcatatgtaa acagtaataa agacactaag aagactgaaa
      121 atttgactcc agactaggtt agtcaaaaag aaggaattca agcaaaacaa attgttatta
      181 agattacaga tcaaggttat gtaacttctc atggcgatca ttatcactac tataatggta
      241 aagttccttt tgatgcgctc tttagtgaag agccattaat gaaagccccc aactatcagc
      301 cgaaagatca agatattgtc agttaggtta agggaggata tattattaag gtagatggaa
      361 agtattatgt ttaccttaaa gatcaagctc atgcagaaaa tgtacgaaca aaagatgaaa
      421 tcaatcgcca aaaacaagaa catggtaaag acgataaagg agctagtgca gaagtatctg
      481 tagcaaaatt acagggacgt tatactaccg atgatggtta tatatagtga gttgaattta
      541 gaatagcaca tcatagtttc taaatcattg ttagaaatta ctttaaaatc cccttatcaa
      601 tttgctcata ttctatttca atctactaat agtaccacat ggtggtcact atcatttcat
      661 tcctgagagt gacttgtcgg caggtgaatt agcagccaca tatgtcttta accctaatga
      721 tattgtcaga gatataggtg atgcttatat agtaagacat ggggaacact atcactatat
      781 tcctaagtca tctcttaaca atcccccatc acactctaac acggaagagg taggaagttc
      841 ttctagttct gtattaagta atccgtcact acatgtccac catgaggaag aagatggtca
      901 tggtttttga tgccaatcga attataagtg aagattcaga aggttttgtg attcctcatg
      961 gcgaccacaa tcactacatc aaggttcaaa ctaagggata tgaagcggct ttgaaaaaca
     1021 agattccatc cctgcaatcc aactatcaac ctggaacttt tgatgagaag gcagtcttgg
     1081 caaaagtaga tcaacttcta gctgatagca gaagcatcta caaagacaga ttgagttagc
     1141 tttaggtcag tttactgaaa gtttgaaaaa aataaaagtt agttgattga ttacttctct
     1201 aaattttggg cacactaaaa agaggtcttg acacctaaac tttaaaatta aagcatattg
     1261 aatccgtgct gctgtgcgaa gcgaatagcg tcttggacga acattgtctt atctggattt
     1321 cttatttctg taaggccttg taatcttgga ttataactct cctgttttag gagtacatgg
     1381 tagatagcaa ccaataatct gcgacagata gcaaggaaga agtagaaagt cttttgaaca
     1441 aggcaaatca actcttggaa caaatccatg aagaaggaat cagacaatcc ttggcagaag
     1501 aagtagaaaa tctaaaagct gccacaaaca aggctgatgc agacttggat gaagtaaaca
     1561 gtcaggtaaa agatgttttg actcgtatcg ctagcgccct tcaacaagaa aaggaaaatg
     1621 ctgagcaaga ttctcagaca cttgtactct atcaaaaact ctacgatatt ctcatgtcgc
     1681 ttcactctta tttagaaagt aataatggat ctgatgcgga ctttgataag gtggatgcat
     1741 tattagatca actttctgct aatagtaaag acaaaacagc tttacttgaa tcgacaaaag
     1801 ctattctagt tttgaatcat caaatccagt caaaagttag cgcaagtgaa gaaacaagtc
     1861 cagcaagaaa tgctgaagca aatagtgata acaccagtgc tgagaaccaa ccaaacgcaa
     1921 ctgcagaatc taacattgaa actgctagcg acgaaaacaa accaagcaat acaagagatt
     1981 ctaaacctgc tgaatcaact tcagaaaatg aaacaacaga atcttctaca actactggaa
     2041 atcaagaaaa accagtagaa taaaaagaaa ggcgaagtag ctgagccacc tcgtcttttt
     2101 agcctttata agctacgatg ccaatgatgg tatcaactgc acgttccata gtctgaaggc
     2161 taacgtattc aaaacgtccg tgcatatttt cgccacctgc aaagatattc ggagttggga
     2221 ttcccataaa ggaaatctta gagccgtctg ttccaccccg gattggttcg ataataggcg
     2281 tgatacctag atcttccata acggctttag caatggtaat tggagtcata tctttttcaa
     2341 tgacttcttt catattgtag tactggtctg tcaagttgag agtgacacgg tcgctcccaa
     2401 gttcttcatt catcttatca gcgatagatt gcatggatgc tttacgcgct tcaaaggcat
     2461 ctttttcaaa atcacgaatg atgtagcttg cacgcacctc ctcaacacta cctgtcacat
     2521 ccattagatg gtaaaaacct tggtaacctt cagttaactc aggtcggtca ttttctggaa
     2581 gttgattatg aaaatcaatt gctagctgaa gggcattgac catctgccct ttggcagtac
     2641 cagggtggac attacggcct tggaaatgca attcagcacc agcggctgag aaagtctcgt
     2701 actgaagttc acctagtgga ccaccatcaa cagtgtaggc aaaatccaca tcaaaatctt
     2761 ctgcatcaaa tttattggca ccaacaccga tttcttcatc tggaccaaaa ccaacacgaa
     2821 tctcacagtg cttaatttca ggatgagcag ttagatattc aatggctgtc ataatttcag
     2881 caattcctga cttgtcatca gcacctagca aggttgttcc atctgttgtg atgagtgttt
     2941 gtcctggata tttttcaaga ctcttgaagt cggctggatc gagtttgaaa ccagaattcc
     3001 ctagttcaat cacaccacca tcgtagtttt caattacctg tggattgact ccttcagcat
     3061 taaaatcagc agtatccatg tgcgatataa aaccaatctt acgtgttaaa gacggatcgt
     3121 tggctggcaa ggttccaata gcaaaaccat tcggtagata gtaaacattt tgcagtccaa
     3181 cacgtttcat ttcaggaatt aggacatttg ttgcgaagtc aacctgactc tgtgtacttg
     3241 gagtagtagt agagtgttca tcagagcgcg tgttgacctt aacgtaggtt aagaagcggt
     3301 ccaagagatt tggataagtc ataaaaaaac tcctttttta tcataa
//
LOCUS       DAVKUR010000096         3183 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKUR010000096 DAVKUR010000000
VERSION     DAVKUR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.096"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(366..899)
                     /locus_tag="VW749_002045"
     CDS             complement(366..899)
                     /locus_tag="VW749_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0176010.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(988..1764)
                     /gene="recX"
                     /locus_tag="VW749_002046"
     CDS             complement(988..1764)
                     /gene="recX"
                     /locus_tag="VW749_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0176011.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1802..3157
                     /gene="rlmD"
                     /locus_tag="VW749_002047"
     CDS             1802..3157
                     /gene="rlmD"
                     /locus_tag="VW749_002047"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0176012.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1017 a          550 c          569 g         1047 t
ORIGIN      
        1 tgatagatta aatatcattt tctctgttaa gatattgttt ttaaaatatt gtactaaatg
       61 attgatgcta tgtggaaata caaaaaaatg tttttgatac gaagttgacc tgtatttttt
      121 atactaatca ttttcgtatt ttttgtatta aacgatataa gtttgttgta aacttacaag
      181 gaataaagac attaaaaaat aacagtatat ctatttgttt tatatatttt acgaattttg
      241 cataaatctc tttctagtaa tgtgttgtaa ctctgctata atagatttat tcctttttgt
      301 gtttacacaa tttattttat actaccaaaa aaaggtcagg attttgttcc tgacctttga
      361 caactttacc gattctttag ttctacatag cgcttgtacc aaatgtttac ataggcttct
      421 gagaaaggac cacgtccatt gttaatccaa tcaacaagaa ttttgacatg ttcttttaaa
      481 atatagtcca agtcatcaga ataattcatt ttgcgtttgt gacgctcgta ctcttcaacg
      541 tccaagagac gtttttcccc atctgtaaaa attttaacat ccaaatcgta atcaatatac
      601 ttcagtgctt cttcatccag atagtagggg ctagccatat tgcaatagta agaagttcca
      661 ttatcacgaa tcatggcaat gatattaaac caatatttct tgtgaaagta aacaatagcc
      721 ggttctcgag tgacccaacg acgaccatca ctttcggtaa caagtgtatg atcgttgaca
      781 ccaataatgg cgttttctgt tgtttttagt accatggtgt cccgccaagt tcggtggaga
      841 ctcccatcat gcttataact ttgaattgta ataaagtcgc cttcttttgg aagcttcata
      901 actaaccaac tttctacaat ttataagttt atcatttact attgtaccat aaaattacct
      961 aaaatctgtg aatttcactt ggaaatatta aagatattct ctaagagcgc ttgctatatc
     1021 cgaaaaatcg tagccctttc gtgctaaaac ttgagttaaa cgctgcttca gttcgtatcc
     1081 ttcatacttt cgagcatact tagtatattg cttatcaagt tccttgaaga tgagttcttg
     1141 agtcgtttct tggtcaactt ggctatctaa gtcgtcaaag gcaattttag catcagaata
     1201 agagaagccc ttgttagtca agttctggat aatcttatct tgcagggcac gagctggaag
     1261 ttttccctca tattttttca atagtttatt ggctacacgt tgagcaactt cagaaaaatc
     1321 aaattctttc aagttctctt ctatagtaga ttttgaaatc cctttttgag ctagtttctg
     1381 agtcagcaca taaggaccct tgtctcctga aagttgattg gtattgatga tagcataagc
     1441 gtactgacca tcattaatcc acttatcttc tttaagatta gcaataactt gagaaacgat
     1501 gttttcatca atatcgtatt ttttcagata ttctctgact tctttttcag tgcgtgcttt
     1561 aaaggataag tggtagaggg ccagattctt accataagaa aattgagcaa agtcttgaat
     1621 ctctttcaat tcctcttcgc ttatcacctt atctctcgat aacataaaac gaacaattgt
     1681 atcttcggtg atatagcatt tgtcgccatt atcaagctcc atcagataga gtcttttttt
     1741 cttttcaagt tttgtgattt tcatagctct attataactc aaaatgtgat aagatagggg
     1801 tatgaatctg aaagtgaaac aaaaaatacc attaaaaatc aaacgcatgg gaattaatgg
     1861 tgagggaatc ggcttttacc aaaaaacatt agtctttgta cctggagctc tcaaaggcga
     1921 agatatctat tgtcagatta cttctattag acgcaacttt gttgaagcaa aattactgaa
     1981 ggtcaacaag aagtctaaat ttcgaattgt gccatcttgt actatttata atgaatgcgg
     2041 aggctgccaa atcatgcacc tgcattatga taagcagctg gagttcaaga cggacttact
     2101 tcatcaagcg ctgaaaaaat ttgctcctgc aggatatgaa aattatgaaa ttcgtccaac
     2161 tattggaatg caggaaccaa aatattacag agctaagtta caatttcaga ctcgaaaatt
     2221 taaaaatcag gtcaaggcgg gcttatatgc acaaaactct cactatttag tagagttgaa
     2281 agactgcctg gtacaagata aggaaaccca agtgattgct aatcgcttag cagaattact
     2341 tacttatcac cagattccaa tcacggatga gagaaaagtt ctaggtgtcc gtactattat
     2401 ggtccgacgc gcgagaaaga ccggacaggt tcagattatt attgttacaa accgccagct
     2461 taatttaact caattggtaa aagagttggt taaagatttc ccagaagttg tgacagtagc
     2521 tgttaataca aatacagcta aaaccagtga gatatatggt gaaaagacag agattatctg
     2581 ggggcaagag agtattcaag aaggtgtact caattatgaa ttttcactat cccctcgagc
     2641 tttttatcaa ctaaatcctg agcaaacaga agtcctctat agcgaagcag taaaagcgct
     2701 ggatgttgat aaagaagacc atttgattga cgcttattgt ggagttggaa cgattggatt
     2761 tgcctttgca aagaaagtaa aaacactcag aggtatggat attattccag aagctattga
     2821 agatgccaag cgaaatgcta aaagaatggg atttgacaat actcattatg aagctggaac
     2881 ggcagaagag attattcctc gttggtacaa ggaaggctac cgagcagatg ctttgattgt
     2941 tgacccacca cgtacaggtc tggatgataa gttattagat actattctta cttatgtacc
     3001 agaaaaaatg gtttatattt cttgtaatgt ttcgaccttg gctcgtgatt tggtacgctt
     3061 agtagaagtc tatgatcttc attatatcca gtcggtcgat atgttcccac atacagctcg
     3121 aactgaagct gttgtaaaat taataaaaaa agtttaaaaa agtagttgac aaagtttgaa
     3181 aag
//
LOCUS       DAVKUR010000097         3153 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKUR010000097 DAVKUR010000000
VERSION     DAVKUR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.097"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..421)
                     /locus_tag="VW749_002048"
     CDS             complement(<1..421)
                     /locus_tag="VW749_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0176013.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINRLANLPYNSSKCNELIKY"
     gene            515..1735
                     /locus_tag="VW749_002049"
     CDS             515..1735
                     /locus_tag="VW749_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEV0176014.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1748..2929
                     /locus_tag="VW749_002050"
     CDS             1748..2929
                     /locus_tag="VW749_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0176015.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT         1072 a          420 c          648 g         1013 t
ORIGIN      
        1 gatattttat taattcatta catttagatg aattataagg aaggtttgca agacgattaa
       61 tctgttgttc agcaatcaat tttatgtgat aattgcataa acttttttct tgcttttgtt
      121 ttaactctat tttatccact aattcttgaa gtaaaaatat atctgaagaa tttacagcat
      181 gttctaattc ttcaaaaaga cattcttttt tggaataata acaatgaact aattcttcaa
      241 attctgaaaa tgatattcca agacggttta acagaatata aaaatgatta atagataatt
      301 ttgtaatgcc attttcgaaa cgagaaatag ttgattcact aatttcatta catgataaat
      361 ctttaaggcg aaaatttttt gaaatacgaa tatcctttaa aactgctccg aaattttcca
      421 taatgttcct cttccatttc tgcaaaaaat aaaacgcttg ttttttattt atgatatgat
      481 tatacaaaaa taaaatagaa aggacaataa tatcatgaaa aaaattttat tgtcaacagt
      541 tgctttatta agcttagtag catctctgct agcaaataat ccagtttctg ctcaagaatc
      601 atcctctcaa gcaacttata gtaagtcaag tggaagttgg ataaaatctg gtaaccgttg
      661 gtggtataag cattctgatg gttcttatac tacaaatgga tgggaaaaaa taaatggtac
      721 ctggtactat tttgatagtg aaggttggat gaagacaggt tggattaaag aatatgggaa
      781 atggtattac ctagatgata gtggtgctat gaaaactgga tggtgtttgg tttctggtag
      841 ctggtattat ttaaatagta gcggtgtaat gcaaacggga ctacagacta tcaatggaaa
      901 acaatattat ttagctgccg gcggtgctat gcagacaggt tggcacaata tcggagatga
      961 tacctatttc tttgctaata gtggggaaaa tcaaaatatc aatcgtcgtg ctttagttct
     1021 tggtgaaaca tcaacgagag cagtacctat tgcagatgtt aatgctatgg aaaaggtttt
     1081 taataaccaa aactttagtg aagttgttcg tttcccagat agaacaaaat ccgagataat
     1141 tgcaaaaatg caagagcttt ttgaatcttc tagcgaaggc gatgtgaact atctttactt
     1201 tacttgtcat ggaggaagag atggaagaat ctatattggt agtgatggcc tagcattttc
     1261 tggttgggaa ttggcgtccg ttttgaaaca atacaaaggt aagtttgttg ttatgctgga
     1321 ttgttgtcat gctggaacaa ttatttctaa agataataca ggtgaaggca atgaaggagc
     1381 ctctacggaa tattttgatt tagatgaatt tgtatcagga ttttctaata tggatggtaa
     1441 cgaaaaatca ggtgagatga ttgactctaa atttttagta ttatgctcat caagaggtgc
     1501 agaatactct agtggtggat cattaagttt agcgactaaa tattggtctt taggttcagg
     1561 atggaatcct ctacagaatt cacaagcata tttagcagca gaccaaaata ataatcgcag
     1621 aatcacatta aatgaattgt atacatactc tcgtgaacaa gttttgaaac aaaattctaa
     1681 ccagcatatt gaagtttatc ctgacaacag tcaatttgtg ttatttaaga aataaggggg
     1741 caataaaatg aaagtatcaa aaaaaattac actatttagt ttgtcttttg caggttttgt
     1801 tttattgact ttacctcaag caggaaaggc ttttgaactt aaagaagact gggcatttaa
     1861 aggtggcatt cgatacgaga atgggaaagt cagcaaaatt aataatggat atgaagtaaa
     1921 tattaaagtg ttagatttac ctagtactag cgcaatcgaa tggacagtta gattgaatgg
     1981 agaaaagcaa aatactaact tcttagcgga ggaaagaact gtatctaaaa ctgaagataa
     2041 gggacgtttc ttgcactttt atatccccta tggatatcgt ggggatattg tagtagaggc
     2101 taagagtgga aacgaagtga agacttggtc tactaaggta gttgacgatg tttattcaga
     2161 ttctgctaag agtggctact ttattctcga tggggaacaa atcttagaaa gttcatggga
     2221 ttccgtaaat gagtcttata ttgcaacgct tccaactgta acatcaggaa aaactgttgt
     2281 tgcttggcgt gaaaaaggaa ctcttaattt aattaaacca ggaagaattg ctcggcaata
     2341 taatagcagt ggatcatatg tagaactttc tccaatcttt gaaactgcta gttggctaaa
     2401 atcaaaccaa aactggtact atcaaaaaca aggtcaatta gttcaaaatt cttggatcaa
     2461 ggatcaggga agctggtact ttatggatga tgaaggggtt atgtttaatc aaacatggct
     2521 acaccaaggt ggaagctggt atgcctttaa gtcatcagga gccatgattt cagctgattg
     2581 gttgtatgat aatggttctt ggtattacct aaaggactca ggttctatgg taacaggatg
     2641 gcttaaaaat ggaggctctt ggtattacct aaacaagtca ggttcaatgg ctacaggttg
     2701 gattaaagat agtggaactt ggtattatct aaagaattca ggctctatgg cgacaggctg
     2761 ggtgaaagat agtggctctt ggtattatct aaagaactca ggttcaatgg caacaggttg
     2821 ggtcaaagat aatggtaagt ggtactatct cgcatcatct ggtaatatgc ttcgcaatac
     2881 acgcacacca gatggctatt atgtagatgg cagtggcgct tggaaataaa tttttaaaag
     2941 agaaaatcta ctgagaaggt agattttctt tttagttaat gaatatagaa taaagtagat
     3001 caggactggt ctattttatt ttgtaactat taatgaatag tcttaatgat gaagttactt
     3061 tctgaagata tttaattgtg ttgagatttg ataaaactat agcggattga aataagatat
     3121 aaacaaagag attatggaag tcaaattaat ttc
//
LOCUS       DAVKUR010000098         3005 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKUR010000098 DAVKUR010000000
VERSION     DAVKUR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.098"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1062
                     /locus_tag="VW749_002051"
                     /pseudo
     CDS             1..1062
                     /locus_tag="VW749_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1171..1470)
                     /locus_tag="VW749_002052"
     CDS             complement(1171..1470)
                     /locus_tag="VW749_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0176016.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1635..2086)
                     /locus_tag="VW749_002053"
                     /pseudo
     CDS             complement(1635..2086)
                     /locus_tag="VW749_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            2168..2822
                     /locus_tag="VW749_002054"
                     /pseudo
     CDS             2168..2822
                     /locus_tag="VW749_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            2910..3005
                     /locus_tag="VW749_002055"
                     /pseudo
     CDS             2910..3005
                     /locus_tag="VW749_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1008 a          520 c          571 g          906 t
ORIGIN      
        1 tgacatgaag gctggactaa agatagagtt tctcttgaat acggcctccc aagtcgtacg
       61 atacttctta actggctagc acaatacagg aaaaacgggt atactattgt tgagaaaaca
      121 aaagggagag tacctgagag cggagaatgc catcctaaaa aagttaagag aactccgatt
      181 gaaggaggaa aaagagaaag aagaaagaca gaaattgttc aagaattaat gactgagttt
      241 tcgttagttc ttcttctaaa atccattaaa ctagctcgtt cgacctacta ctatcacttg
      301 aaacagctag acaaaacaga taaggaccaa gagcttaaag ctgaaattca atccattttt
      361 atcgaacaca agggaaatta tgcttatcgt cggatttatt tagaactaag aaatcgtggt
      421 tatctggtaa atcataaaag agttcaaggc ttgatgaaag tactcaattt acaagctaaa
      481 atgcgacaga aacgaaaata ttcttctcat aaaggagacg ttggcaagaa ggcagagaat
      541 ctcattcaag gccaatttga aggctctaaa acaatgggaa agtgctatac agatgtgaca
      601 gaatttgcca ttccagcaag tactcaaaag ctttacttat caccagtttt agatggcttt
      661 aatagcgaaa ttatcgccta taatctttca acttcaccca acttagaaca agtacaaaca
      721 atgttggaac aggcattcac agagaagcac tacgagaata cgattctcca tagtgaccaa
      781 ggctggcaat atcaacacga ttcttatcat cagtttcttg agggtaaggg aattcaagca
      841 tccatgtcac gtaagggaaa cagccaagac aacggtatga tggagtcctt ctttgggatt
      901 ctgaaatcgg aaatgtttta tggctatgag aaaacattta aatcacttaa tcaattggaa
      961 caagctattg tagactatat tgattactac aacaataaac gaattaaggt aaaactaaaa
     1021 ggacttagcc ttgtgcaata cagaactaaa tccttcggat aaattatttg tctaactttt
     1081 tggggtcagt acaaaactct tgctactatg cgttttgtta tggaaagact tattggactt
     1141 tctctcaaat cgagttttta ctcaattttc ttacttgatt gggattgaaa ttccaattaa
     1201 tttctctgag tagagtgtct tgatattggc ttcatcaaca gaggtcttat caattttacg
     1261 tttcaagaaa aattcttgaa tggtttcgat ttcaggctca cgaatagcac ggtgtttgtt
     1321 tgagatgagg atttcatagt gaagcggagc ttgggtaaaa ataacatctg tattccctgc
     1381 agaataaacc tcaacaaggg ttgcatcggt actttctagt tgacttttta caagttgcga
     1441 gtgtgagttt gtcgtattga taagcttcat aatatttcct ccgattttct aattctatta
     1501 taacactttt tgaataaagt cgcttgattt atactcaatg aaaatcaaag agcaaactag
     1561 gaagctagcc gcaggctata cttgagtacg gtaaggcgac gcttacgtga tttgaatttt
     1621 attttcgaag agtattagcc aatcttatgc tgttttttcc aagattcaat ggcccattta
     1681 tggctaccac gtttaaggtt tttgatagcc tcgtcaatag ggaaccaggc aatatgatta
     1741 aagttttcta gtggcttttg tacttctttg aaaggagttg cttcatagag gtaggcagga
     1801 ttgtagtagt aggtatcacg atgacgagaa tagaaatatt cgtcagcttg tccgtaatag
     1861 gtaccaattt ctgctgtgaa accaagctct tcaatcaact cacgctttag ggcttcctga
     1921 tgattttcac ctgcttcaat ttttccacat ggtaggaacc aagcaccatt tggttcttga
     1981 acaagaacaa tttgtttttg ttcaggatta gggataactg catatacgcc atagcgagta
     2041 atatagtctg tattcacttt ttttctccga aagttgggtt tgccattgca ttttcctcat
     2101 tatctagtat cgttattatt atagtgaaat gaaccaaaaa tagtacacaa tgtggtataa
     2161 tctttttatg gcatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac
     2221 aggtagtata acagaagcat cacacgtttt ccaaatctca cgtaatacca tttatggctg
     2281 gttaaagcta aaagagaaaa caggagagtt aaaccaccaa gtaaaaggaa caaaaccaag
     2341 aaaagttgat agagatagac ttaaaaacta tcttactgac aatccagacg cttatttgac
     2401 tgaaatagct tctgaatttg gctgtcatcc aactaccatc cactatgcgt tcaaagctat
     2461 gggctacact cgaaaaaaag aaccacacct actatgaaca agacccagaa aaagtagcct
     2521 tatttcttaa gaattttaat agattaaagc acctagcacc tgtttagatt gacgaaacag
     2581 gattcgatac ttatttttat cgagaatatg gtcgctcatt aaaaggtcag ttaagaagag
     2641 gcaaagtatc tggaagaaga tatcagagga tttctttggt tgcaggtcta acaaatggtg
     2701 agttaatcgc tccaataact tacgaagaga cgatgacgag cgactttttt gaagtatggt
     2761 ttcagaaatt tctcttacca acattaaaca caccatcggt tattatagta aaacgaaata
     2821 agaataggac aaatcgatca ggacagtaaa atcgaattct aacaatgttt tagaagtaga
     2881 tgtgtactat tctagtttca atctactata ttatggataa tgcaagattc catagaatgg
     2941 ggaagctaga acttttatgc gaagagtttg ggcataaact tttacctctt cctccctact
     3001 cacct
//
LOCUS       DAVKUR010000099         2830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKUR010000099 DAVKUR010000000
VERSION     DAVKUR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.099"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..143)
                     /locus_tag="VW749_002056"
     CDS             complement(<1..143)
                     /locus_tag="VW749_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0176017.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEA"
     gene            348..536
                     /locus_tag="VW749_002057"
     CDS             348..536
                     /locus_tag="VW749_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0176018.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            693..1058
                     /locus_tag="VW749_002058"
     CDS             693..1058
                     /locus_tag="VW749_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0176019.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            1061..2728
                     /locus_tag="VW749_002059"
     CDS             1061..2728
                     /locus_tag="VW749_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0176020.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT          901 a          516 c          624 g          789 t
ORIGIN      
        1 gcttcttttc ctttctgttg ataggctagt agcagacgat tgatttgtct ttcagaaaga
       61 ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc ttttatcaca
      121 agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact attctaccaa
      181 atgtgacatt ttcacgttcg atttactaaa gacattatca cattcgaatc acaacacaaa
      241 taaaaaatct tccaattccc ttgcaaaaaa caagaaagtg tgataacata gtacggtatg
      301 tggtgctagc acatccgcta tattagatct aataggagga aaacacaatg gctaaagtat
      361 gttactttac aggtcgtaag actgtatcag gaaacaaccg ttcacacgcg atgaaccaaa
      421 caaaacgtgc cgtaaaacca aaccttcaaa aagttactgt tcttatcgat ggtaaaccta
      481 aaaaagtttg ggcttcagct cgtgctttga aatcaggtaa agttgaacgc gtttaataat
      541 aaaagcaaag gagaccttag ggtctttttt cttttattgt gggtataaca tcgtttgaaa
      601 aatagagtaa atatccgctg atacatcatt ctgcttttac acttgggctg aaatatgata
      661 aaatagagta tcaactagtt gaggtaaaaa ggatgactgt aaaaattaat acaaaagatg
      721 gtcaaatcga actaacagat gaagtgattg caaccgtcgt aggtggagca gcaactgaga
      781 tttttggtgt ggtcggtatg gctagtaaaa atgccctcaa agataatttc caagccctgc
      841 taggtaagga aaattattct aaaggtgtcg tcgtaaaggc agccgaagat ggcagtattg
      901 cagttgatgt atataccgtg ttaagctacg gaacaaagat tagtgaagtg tcaaaaaaca
      961 ttcaagagcg tgttgccttt agcttggaaa accagcttgg aattactgct cagactgtaa
     1021 atgtctacat tcaaaatatc aaagttgtag gagaataacc gtgtcaaaga ttactactag
     1081 cttatttcaa gaaatggtgc aggctgcatc aactcgcttg aataagcaag ctgaatatgt
     1141 caattcatta aacgtctttc cagttccaga tggagatact gggacaaata tgggaatgac
     1201 cattgaaaat ggtgctaaag aagttgcaga caagccagct tctacagttg gagaagtagc
     1261 gagcattctt gccaaagggc ttttgatggg tgcgcgtggg aactcaggag tgattacatc
     1321 tcagcttttc cgtggatttt cccaagctat caaggataaa gacgagttaa caggtcaaga
     1381 cttggctctg gccttccaat caggtgtgga agttgcctat aaggcagtga tgaaacctgt
     1441 tgaaggaacg attttgacag tttctcgtgg agctgctatc ggtgctaaga aaaaagctga
     1501 gcaaacagat gatactgttg aagtcatgcg cgcagccttg gaaggtgcta aaacagctct
     1561 agctaaaaca ccagacatgc ttccagtatt gaaagaagtt ggcgttgtgg actcaggtgg
     1621 tcaaggattg gtcttcatct acgaaggttt cctttcagcc cttactggcg aatatattgc
     1681 atctgaggac tttgtagcga ctcctgccaa catgagtgag atgatcaatg tagagcatca
     1741 taagtctgta gctggtcacg tagcgactga ggacatcacg tttggttact gtactgaaat
     1801 catggtagct cttaagcaag gtccaaccta tgctaaagat tttgactacg atgaattccg
     1861 taactacttg gatgagcttg gggattctct cctcgttgtt aacgatgatg aaattgtcaa
     1921 agtccatgtt catacagaag atccaggact tgttatgcaa gaaggtctca aatatggtag
     1981 cttggtcaag gtaaaagttg acaatatgcg taaccaacac gaagcacagg ttgagaaaga
     2041 agctactcaa gttatcaagt cggctgaaga aaaagagtat gctttgattg ctgtggtggc
     2101 tggtaaaggt ctagcagata tcttctgttc tcaaggcgtg gattatgtta tcgaaggcgg
     2161 tcaaaccatg aacccttcaa cagaagactt tatcaaggct gttgaacagg tcaatgcccg
     2221 taacatcatc ttcttgccaa acaacaagaa catcttcatg gcagctcaat ctgcggcaga
     2281 agttttggag caaccagcag tagtggtaga ggctcgcact cttcctcaag gtatgacaag
     2341 tcttcttgcc tttgatccaa gcaagtccat tgaagaaaac caagagcgta tgacagctgc
     2401 tcttagcgat gtcgttagcg gaagcgtcac aacagccgtg cgtgatacaa cgatcgatgg
     2461 cttagaaatc catgaaaacg ataatctagg tatggtggat ggaaaaattc ttgtgtcaaa
     2521 ccctgatatg caccaaacat tgactgaaac cttgaaacat atgttggatg aagacagtga
     2581 aatcgtaacc ttctatgtcg gtgaagacgg aagcgaagaa cttgccaatg aaatcgctca
     2641 agaaatcgta gaagaattcg aagacgttga agtcgagatt caccaaggtc aacaacctgt
     2701 ttacccatac ctatttagtg tggaataaga ttaatgaagg actgagaaat cagttctttt
     2761 ttctttttta gtaaatgaaa tcggtatctt tttaataaaa acaaaaataa cattcataaa
     2821 taaacgttaa
//
LOCUS       DAVKUR010000100         2782 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKUR010000100 DAVKUR010000000
VERSION     DAVKUR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.100"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..992)
                     /locus_tag="VW749_002060"
     CDS             complement(<1..992)
                     /locus_tag="VW749_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0176021.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEA"
     gene            complement(1002..1955)
                     /locus_tag="VW749_002061"
     CDS             complement(1002..1955)
                     /locus_tag="VW749_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0176022.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            complement(1948..>2782)
                     /locus_tag="VW749_002062"
     CDS             complement(1948..>2782)
                     /locus_tag="VW749_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0176023.1"
                     /translation="KLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWTYSMGDAFI
                     CVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNNKKIICYVG
                     RLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRDNFRLLGEI
                     YPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEHRVDGFLFE
                     KEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYDELLEKSSH
                     G"
BASE COUNT          950 a          524 c          296 g         1012 t
ORIGIN      
        1 tttgcttcat ataacggaaa atctctattc acctcatttg gttcgatatc attcatttta
       61 tttgactcaa ttggattaat tgaatacaat tttaaaaaaa taggcttcgt accaataata
      121 gaggataatt gacctcctaa ttcacctagc gctgtaaaaa taacacctgt tagtgctcct
      181 attgcttcaa tagtaccaat tttcactatt ccttttattg caagatagcc tgttaaaaaa
      241 acgagagata tctgaaaaaa aatattgaga aagaagctaa tagcgcctgc taacgtttct
      301 acagttgtct ttctttgtat aaccatcttt aataaaattc ctgcttcttt aattttctta
      361 ggcaatacat ataaaagatt caaggacgct aacacatcaa atccattcaa tatagtctca
      421 ctagatttta aaaaagcttc attttggcta gttaaattta gactaacttc tcgcattttc
      481 gatgcaaaga tttttggtac aagtagcata atcattaatg aaaacaaggt ggctacagtc
      541 aatgaccaat gatagtgatt aagagtcaca actgcaaata tagtaccaga aattcctttt
      601 attactaaaa aaagttgttt aaaagcctga tcatttaaag tctgaacatc attatttagc
      661 cacgaaagat atgttcctga tgatttacta tgaaattctt gataggtaga gttagagatg
      721 tctgtggcaa ctctatttcg aatctctaga ttaaactctt ggatcacttc aacctgataa
      781 tttttcacta cccagtcaag gaatattatc ccacaccaga caatcatttg gtagattgac
      841 aatttcaaaa accgctctaa attcatcgca attaattcat tcaacaccag agcattaata
      901 gttgctgcat aaattagcaa taattgacca gcaacaataa atatcgttaa taaactaaat
      961 ttttttatat ttgattttat aatagtatac acaatagttt ctcactttct aaattttaat
     1021 tgaacatagt tgtcatatat acaatagaaa aaaccaaaat aatataataa catgtatttc
     1081 aaaaaaagaa attcgttaaa aattttttct tctcttgcct tcttgattac ttttaaagcc
     1141 ttgcatttgt ctcctattaa tagtaaccgc tttatgttta aagaataata tttctttgta
     1201 accaatattc tctcgttgaa actcaataaa ttaaaatatt tcctacagta attataatat
     1261 tcttcatctg cattaattgt tttttgtgtc actccagtga taccgttttc tttactgtga
     1321 gcgtagtaat tcaccaagaa ttctcgcact atatcaattt ggtatccttg agcaagtagt
     1381 tttaataaaa caacaccgtc ctgatgtgaa tctattttct caaaaccatt aattaattct
     1441 agcacctctt ttttacacaa ccaaaatgac gtacctgcta tattgtgaac catttgaaca
     1501 aacaagggat ttccaacaaa atcggtcttc tcctcttctc gtgtaccatt tggataaatt
     1561 attattccat aactataaac taaagctaaa ttcttcattc tactcttttt aaaacaagcc
     1621 atcaacttta aaattcgatc tggcatatat tcatcatcat cgtctaaaaa tgatatatac
     1681 ttacctctag aattttttat acctatgttt ctggcattag ttgcacctaa atcttcatta
     1741 cttaaaatta acttaattct atgatttgta tagccaaatt gatggataat tttatttctt
     1801 aaatttacat tactataatt atcatcaata attataactt cgatattttt ataactttga
     1861 tgtaaacaac ttttcacagc tctaatcaga gattcatacc tattatgtgt tggtattata
     1921 atacttacta attcttgatc tatattccta tccatgacta ctcttctcta ataattcatc
     1981 atatactctc atggtttcta caaacatttt ttgcacagaa aaatgttttc ttatttttga
     2041 tttactattc tcacctatat atttcaaata ctcagaatca ttgagtaaaa aattagcaca
     2101 agcacacact ccctcaacat cttccttctc aaataaaaat ccatcaaccc tatgttcaat
     2161 aatttcactt aacccgccaa cattactagc taaaaccgga gttccttgtg acattgactc
     2221 taaaacacac ataggtattc cttctgtatc agaaggaata tacaataaat ccgatatttg
     2281 gtaaactata gtagctggat agatttcacc aagtaacctg aaattatctc tacatttcaa
     2341 atggcaaatt ttttctttca aagcagccca catactacca tttccagcca taataaaaat
     2401 cacatcttct ctgactaaaa ataatttttc tgcaaattca aggaatctat ccggcctttt
     2461 ttctggatcc aaccttccaa cataacaaat gatttttttg ttatttggaa tacaaaattc
     2521 ttttttaaag tcttgaacac ctactacatc taaatcgcta tttgatacat taattccgtt
     2581 atttattgca actatcttct tattttttat tatactctcc aatctttttt tcatagtttc
     2641 agatacacaa ataaaagcat ctcccataga atatgtccaa aaatcaaaat aagtcaagaa
     2701 tttctttttt aagttatatt caacccatcc atggcatgtt atcactgtct taacctttcc
     2761 aaatccattc ttgtcaagtt tt
//
LOCUS       DAVKUR010000101         2536 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKUR010000101 DAVKUR010000000
VERSION     DAVKUR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.101"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..391)
                     /locus_tag="VW749_002063"
     CDS             complement(<1..391)
                     /locus_tag="VW749_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176024.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYE"
     gene            complement(405..1118)
                     /locus_tag="VW749_002064"
     CDS             complement(405..1118)
                     /locus_tag="VW749_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0176025.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1578..1958)
                     /locus_tag="VW749_002065"
     CDS             complement(1578..1958)
                     /locus_tag="VW749_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0176026.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2375..2527)
                     /locus_tag="VW749_002066"
     CDS             complement(2375..2527)
                     /locus_tag="VW749_002066"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176027.1"
                     /translation="MLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLA
                     LLKESK"
BASE COUNT          823 a          498 c          390 g          825 t
ORIGIN      
        1 gttcgtaggc atattttgct acatgatcta ggtatatatc aaaaaagtca tgaggaaaat
       61 ctcccataca gccattacga ttcatattga ggctatattt tcgattagta agataattcg
      121 gaaatatatt tcctattact ctaagattat ctacttgtga atcccttctc ccaatataat
      181 ccccttcttt gactaatgat ggagatttcc aagtaaaaat taaatcgcca gagaaatttt
      241 tcttatcaaa aaacttaaaa agagattgat aaatactatt tgctaattga caagtgtcag
      301 atgtaaattc ataattaaca gcttcattaa aatcaacttc agacatttca atgtactctt
      361 caatagtaat attagctttt tttgtagtca ttagctaatc tcctttaaaa tgtgatcttt
      421 tcaagaatat ttttatctaa acaatccagc aagtcttggt aagaatagac ttcgtaagtc
      481 ggctgggctt gtgtgtgatt ttcgaggtga tgaggattat accagatagt gtcaatcccc
      541 gcattattgc caccttgaat gtcggcggtt agagaatctc caatcatcag cgtcttttct
      601 ttactaaatc cagcaatttg ctggccaatc ttttcataaa agagagcatc cggcttttga
      661 gtttgcaact gttctgagat aaagacttga ttgaaataag gtgctagacc agattgagcc
      721 aaacgtcctg tctgaatggc agtaatgcca tttgtcgcag catacaagtc ataatcacgc
      781 tcaatgaggc tgtccaagag atcatgagcg cccgatagtg tttgtccctg ctgggcgagg
      841 taaaattggt aacgctgggc aagaaaacta ccgtcttttt cctgtccaaa atgagaaaat
      901 aaacgagaaa agcgcgtgtt aaccagctct tgtttactga ttttcttcag ctccaagtct
      961 ttccagagag ccttgttcat aggaacgtaa taatctttat aagcctgaat atccgcaact
     1021 ccttcttctt ttagaagttg ggtcaaagcc acatcctcag cagcatcaaa atcaagaaga
     1081 gtgtggtcga ggtcgaagag tagaaatttg tagaacaatt tgaggttttc ctttctgaaa
     1141 attcattaaa aacattatat cataaagcac ctcatacaat taactaattt aatcacttaa
     1201 aaaaaattcg aacactttct atacaactga cagctcaaat ctttcagaat agaacaatac
     1261 taactatcga gcacccccgt cttcataaat atatgtgtaa ttctagacct agaattccta
     1321 taaactaaat gctttcatac tcttccaagt aattgattgc cttaaatttt aatttttgaa
     1381 ggattctaaa gctagaatag ccccatcaca atcagttttg attgattcac aatttagaaa
     1441 cactatagtt tcactcctgt taaaataaaa aggaactgca taaagcaatc cctttctaat
     1501 tttgaaatca tttacttaac attttatagt tgagataatc aatagcttac ctataaaaag
     1561 agttatagta aaattcctta tttattgatt tcaagctccg ctaactgtgt ttgaataact
     1621 gacagttctg caccagcctg cagaagagca gctgcattat aggcaccttc tacaattgga
     1681 accctgttga tgatgatact tttatcactg aaatcagtca ccatttttaa gttcatttta
     1741 gcagaaccta ggtcaaaaaa ggcaagtaaa gtatctgctg gattttcgga aacaacccta
     1801 tctacttgat caaaactcgt tccaattcct ccgccctcgg ttcctcctac ataagtaatc
     1861 ggaacatctt tagctacttt actaatcagt tcaacaacac cttctgcaat gtgtttggaa
     1921 tgtgaaacga taacaagacc aataccaata ctttccatca aaccacccca gtttctaaaa
     1981 tagcagtaaa gagtaatcct gatgagaatg atccaggatc aatatgtcca agaaaccata
     2041 tgctcctaag acaagagcca acagactggt catcaataat agtattgttc tttttttcat
     2101 cattactcct taactagtgt ttaactgatt aattagccag taaatagttt atctttattt
     2161 acactatctg ttaagatata gtaaaataag aacaggacag tcaaatcgat ttctaacaat
     2221 gttttagaag tagaggtata ctattctagt ttcaatctac tatattttgc acattttcat
     2281 gaaaaaaatg agaactagaa ctcacattct gctctcattt ttcgttttcc cgttctccta
     2341 tcctgttttt aggagttaga aaatgctgct acctttactt actctccttt aataaagcca
     2401 agagactatc tacttctgct gaaatagtgt tattatcttt cgttccgaga agaagactac
     2461 tttttagacc agtcaatgtc tccacagcat tttgtctaat actagaatct gttacttttt
     2521 ctagcaaggc ctccgc
//
LOCUS       DAVKUR010000102         2521 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKUR010000102 DAVKUR010000000
VERSION     DAVKUR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.102"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            76..258
                     /locus_tag="VW749_002067"
     CDS             76..258
                     /locus_tag="VW749_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0176028.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            268..633
                     /locus_tag="VW749_002068"
     CDS             268..633
                     /locus_tag="VW749_002068"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0176029.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            630..1808
                     /locus_tag="VW749_002069"
     CDS             630..1808
                     /locus_tag="VW749_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0176030.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            1977..2521
                     /locus_tag="VW749_002070"
                     /pseudo
     CDS             1977..2521
                     /locus_tag="VW749_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          965 a          358 c          451 g          747 t
ORIGIN      
        1 aaagaaaaaa tcgaaaaatt agctaagaaa tattctgata acttaaacat caaagttcaa
       61 gagagagttc gtgaaatggc aaatgataat aagagccatt atttgatata cagagtttta
      121 ggtatttcat ttgaagaagg agaaaatatc gatttgtatc aaaataaagg tcgtttttta
      181 tacaaatatg ctggttcatt tttagaagaa gctgcagtac tatcctttaa cgaaaaattt
      241 ggtacagaaa atacttaaaa agttaacatt cctaattctg aaagtacaaa acctaagact
      301 tttgaaattg attgtttagt cggagaaaaa cacgcatacg aaataaaatg gtgggatgca
      361 actacagatg gagaccatat aactaaagaa cacactagaa taaaagttat tcataacaaa
      421 ggatatatac caattcggtt aatgttctac tatccaaata gaactcaagc tataaaaatt
      481 cagcaaactt tagaaacatt gtataacggt attggaggga aatattatta tggagattct
      541 gcctgggaac atttaagagc agtgaccggt attgatttac ttagtattct aacagatatt
      601 gcaaataaaa aaacaggggt aaaatcaaaa tgacagtatt aaaaggagat aacttagaaa
      661 tattaaaaac tattgaatcc tcaagtattg atttaatcta tatggaccct cctttcttta
      721 cacagaaaac ccaaaaatta tctaataaca aaaatattat gtattcattc gaagatacgt
      781 ggacttcgat tgaggattac aaagaatttt tgtctgtaag attagaagaa tgcaaaagag
      841 tgctaaaaaa tagtggcagt attttcgttc attgtgataa aattgcaaat catcatatta
      901 gattaatttt agataatatc tttggagcag atatgtttca aagcgaaatt atatggaact
      961 ataaacgatg gtctaattca aaaaagggat tattgaacaa tcatcaaaac atttactttt
     1021 attcaaagtc aaaagatttt aaatttaata caatttttac agagtattct tctactacaa
     1081 atatcgacca aatactagtg gaacgaaaac gagatggaaa ctctaaaact atatataaag
     1141 ttgataataa tggtaactat attctagcaa aagagaaaaa tggagttccc ctttcagatg
     1201 tttggaatat accatttctt aatccaaaag ctaaagaaag agtaggttat cctacacaaa
     1261 aacctattct gttattagaa caaattataa agattgctac tgataaaaat gatatagttt
     1321 tagacccgtt ctgtggaagc ggaactactt tagtagcctc caagattttg aatagaaatt
     1381 atatggggat tgatttatct gaggaagcta tcaatataac tcagcaacgt ctggaaaatg
     1441 ttataaaaac aagttcaaat ttattgaata aaggaatcga agcatataga accaaaactg
     1501 aggaagagga aaacattctt aaattattac aggcaaaaat tgttcaaaga aataaaggaa
     1561 ttgatggttt tttacctaaa cattttcaaa aaaaaccgat acctataaaa attcaaaaaa
     1621 ataatgaatg tctgaatgag agtatctctt tattacagaa tgctataaac tccaaaaaac
     1681 ttgattttgg agtagttata aaaactcatt cagataattt attatttgat tttgatacga
     1741 ttcctgaaaa tataatagta gttgaccatt ttgaacttac aatcgaaaaa tggttaagta
     1801 aaagttaaca gttactatag tttgcaaatt atttacagaa agaacaagaa ttcctaggag
     1861 attattctgg ctatgttcat tgtgacatgt tgcggcagta acttaggact ttagtcctct
     1921 agttctgcct atgcgatagc agtccaaagt ttaggagtaa ggcgacgcta agcttggtaa
     1981 actgcgaaca gctagaagct tatcgtcaac tggaagaagc tgcacttgtt ggatgttggg
     2041 cgcatgtgag aaggaagttt tttgaagcga cccccaagca agcagataaa tcatccttag
     2101 gagctaaagg tttagcttat tgtgatcagt tattttcctt ggaaagagac tgggaggctt
     2161 tgccagctga tgaacgacta cagaaacgtc aagaacatct ccaaccccta atggaagact
     2221 tctttgcttg gtgccgccgt cagtcagttt tagcaggttc aaaactagga agggcaattg
     2281 aatacagcct caagtataaa gaaaccttta agaccatttt aaaagacgga catctggtcc
     2341 tttccaataa tctagctgaa cgcgccatta aatcattggt tatgggacgg agtaaaagag
     2401 tccagtggac tcttttagcc tgagctcagt ttaaaaaagc gagggtggtt attttctcaa
     2461 agttttgaag gagctaaagc aagagctatt attatgagtt tgttggaaac agctaaacgt
     2521 c
//
LOCUS       DAVKUR010000103         2261 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKUR010000103 DAVKUR010000000
VERSION     DAVKUR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.103"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..476
                     /locus_tag="VW749_002071"
     CDS             <1..476
                     /locus_tag="VW749_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="flavoprotein"
                     /protein_id="HEV0176031.1"
                     /translation="FYNVKVILSENSKKFISKELISYFCDKVYDEIFVEEVVPHVFLP
                     YESDLLLILPATANVIGKIANGIADDLVTATVLNFNKKIIFCPNMNSTMWDNHIVQRN
                     VSILKELGHIFLFESKKTYEVGLRKAIDSTCSMLQPQSLVKELIKLENIVLEEGH"
     gene            697..1803
                     /locus_tag="VW749_002072"
     CDS             697..1803
                     /locus_tag="VW749_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV0176032.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            1779..>2261
                     /locus_tag="VW749_002073"
     CDS             1779..>2261
                     /locus_tag="VW749_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176033.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     K"
BASE COUNT          828 a          272 c          387 g          774 t
ORIGIN      
        1 aattctataa tgttaaagtg atactttctg aaaattctaa aaaatttata agtaaggaat
       61 taattagtta tttttgtgat aaagtttatg atgaaatatt tgttgaagag gtagttccgc
      121 acgtttttct gccatatgaa tctgacttac ttcttatttt accagctacg gcaaatgtga
      181 ttggcaaaat tgctaatggt attgctgatg atttagttac agcaactgtt ttaaacttta
      241 ataaaaaaat aattttttgt cccaatatga actctactat gtgggacaat cacatagttc
      301 aaagaaatgt atcaattcta aaggagttgg gacatatatt tttatttgag tctaaaaaaa
      361 catatgaggt aggattgcgt aaagcaatag attcaacatg ttcaatgtta caaccacagt
      421 cgttagtaaa agaacttatc aaattagaaa atattgtcct tgaagaggga cattaaaaac
      481 tactgagaat attaaggagg ggaaaaaatg gaaaattcat caatcgatgt agatatgctg
      541 ttggaagaat tgacacaaga agcaatggtc gttgttgctg ttgataagga ctgttaattt
      601 aaacttatgg caatatatga aaggttactg gatgttttaa attatgcagg cagtagcctt
      661 ttattatata caaatggata aagtaaggat aatacaatga ttaataaaaa aatacaacaa
      721 gttgttttgg aatcattaca gaattttttg aatgggaact tcatttcgcc ttgtgtagtc
      781 tatgattttg gcttgctgga aactgtactt gatgaattta aaaatcaaat tcctgtaaca
      841 ttcaattacc aactttttta tgccgttaaa gcaaattcaa atgagaagat acttgaattc
      901 ttagtagata aaattgatgg agttgatgtg gcgtcattat ctgaattaga tgtggctaaa
      961 aaatttttcc caccaactca aatttctgtt aatggtcccg cattttctta tgaaacttta
     1021 tataatctga ttaaaaaaca atataaagtt gatattaact ttttggaaca tcttcaacaa
     1081 ttttccccaa aagaatctgt tggaataaga gtaacggagc cagatgaact taataatcgt
     1141 atgagtcgat ttggaataaa tatttgcagt gataattgga ctagtaattt acaaaatcct
     1201 ttaattacac gactgcattt tcattttgga gaaaaagatg ataaatttat tgttaagtta
     1261 gataaaatat tatttaagtt acaagaaatt aataaactta gagaggttag agaaataaat
     1321 cttggaggcg gttttatgaa attatttatg gaaaatcgtt tgaaagaatt ttttctatca
     1381 cttatggaaa tctataaaaa gtacgatatt gatagtactg tgactacaat aatagaacca
     1441 ggtagtgcaa ttacttcatt ttctgcctat atgattacta gcccagttaa tgttagtgag
     1501 gtgaatgagc agcaggttat cacgttagac acatcaatat acaccaatac attatggttt
     1561 gttccgcata ttattacaac gttaaattca agtagtaaag agcgttatag tactattctc
     1621 tatggtaata cctgttatga acatgacaag tataaaatga aagtttcgct tccaaggtta
     1681 actcaaaata gcagtatagt gttttttcct gtaggagctt atataaaaag caatcattca
     1741 aatttacatc gtaatgattt tatgcgggag gtatatttgt ggacaaaaaa cttgacatat
     1801 tagataaagt taaggaatat ttaggaaata aaactactca aattctggat aatcaatata
     1861 aagaattttt gaaacttaat gatataaggc gagcgtttgg tatttcagaa aaagtattaa
     1921 acaattcttt taattttacg agtaaagaat ttaatgattt aattaataac gaaaattatt
     1981 tattcgaata tgcatgtaga attagagagg aatggagaaa aaaatgcttt aatcattctt
     2041 atcgttttct atgctcacct ataattacag atgattttct taacacgaag acattgagaa
     2101 gtagccaaat tgaatataaa tatgagcgat atttatcgaa aagttcgata ggcgatagag
     2161 cggttgatgg ctttgtttcc ttcaatactt taacagctaa tggtatgtct gctattaaac
     2221 tatgtcttga gatattaaac tctattttct tcaagaagaa g
//
LOCUS       DAVKUR010000104         2193 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKUR010000104 DAVKUR010000000
VERSION     DAVKUR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.104"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            9..1292
                     /locus_tag="VW749_002074"
     CDS             9..1292
                     /locus_tag="VW749_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0176034.1"
                     /translation="MVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKE
                     KIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLF
                     YILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDE
                     YAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFE
                     EGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIP
                     IYPVIAQKCNQWSGFSIDLARFIDPKTVHSYQKERLLRDGDLMWNSTGLGTLGRLAIY
                     HENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELL
                     TKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1349..2146
                     /gene="psrA"
                     /locus_tag="VW749_002075"
     CDS             1349..2146
                     /gene="psrA"
                     /locus_tag="VW749_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0176035.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          792 a          310 c          388 g          703 t
ORIGIN      
        1 tttctacatt ggttgaaatt gtcagaggtg gctctccacg accaatcaaa gattatctta
       61 cttctgaagt agatggaata aattggataa aaataggtga tactgaaaag ggtgaaaagt
      121 atataaataa tgttaaagaa aaaatcaaaa aatcagggct taacaaaact agatttgtaa
      181 aaaaaggtac atttttgtta actaattcta tgagttttgg tagaccttat attttgaatg
      241 ttgatggtgc aatacacgat ggatggttgg ctatttcgaa ctatgaaaac tcattaaata
      301 aagattacct attctatatt ctttcatcaa atgtagttta ttctcaattt ctatctctaa
      361 ttagtggagc tgttgtgaaa aacttgaata gtgataaagt tgcttctatt cttatccctc
      421 tccccccact atccgaacaa caacgcataa tagaagcaat cgaatcagct ttagaaaaag
      481 tagatgaata tgctgaaagt tataatagac tagaacagct agataaagaa tttccagata
      541 aactaaaaaa atctattctt caatatgcta tgcaaggaaa attagttgaa caagacccaa
      601 atgatgaatc agtcgaagtt ttacttgaaa aaatacgagc agaaaaacaa aaactctttg
      661 aagaaggcaa gattaaaaag aaagatttgg acatttctat tgtttcccaa ggagatgata
      721 actcttatta tgaggaagta ccttgtgaaa taccagaaag ttgggaatgg gtgaggttaa
      781 acgatataac ctcctacatt caaagaggga agtctccaaa atattcaaat attcctatat
      841 accctgtgat tgctcagaaa tgtaatcaat ggtctggctt ttctattgac ttagcaagat
      901 ttattgatcc caaaacagtt catagttacc agaaagaaag attactaaga gatggtgatt
      961 taatgtggaa ttcaacaggt ctaggtacgt taggacgatt agctatttac catgaaaata
     1021 aaaatcctta tggctgggct gttgcagata gccatgttac agttataaga gtcttatcgg
     1081 gggttattaa ttgccatttc atctataatt ttctttcctc tcctattgtt cagtcagtta
     1141 ttgaagaaaa agcgtcgggt agtacaaaac aaaaagaatt attaacgaaa actataaaag
     1201 aatatttaat ccccctccca ccccttcctg aacaatccag aatcgttgat aaaatcgaac
     1261 aatttttcgc ccatattgac gcactaattt agtataatag ttttacgtgc ggtggaattt
     1321 ctatcaaaca taagatagga gttttacgtt gaaagatttt gaattacatt tgaagaaagc
     1381 tggtttagct gaaaatactg tgcgttcgta cctttatggt gttcgatttt tcttggagaa
     1441 ttacgaactc aaaatggaag atttatttga atacaaagga tatttattag acaattttaa
     1501 acctaaaact gtcaatttgc gactacaagg agtaaataaa tatctggctt ttattggtca
     1561 tgatgatttg aaattaaaat ttgtcaaagt acagcaaaaa ccgtttttag aagatgtcat
     1621 tagccatgct gattaccttt ttcttaaacg tagtttgaaa aaagatggta ttttaaaatg
     1681 gcattttgtc gtttggtttt taggtgcaac tggggctcgt gtaagtgaac ttattaaact
     1741 aaaagtagag catgtagaaa tcggttattt tgacatttac tcaaaaggtg gtaaaattcg
     1801 tagactgtac attcctaaaa aattaagaaa tagttgtctt agttggttag aatcagaaaa
     1861 tcgccgaagt ggttatttat ttttgaataa atttaacgaa ccaattacag caagaggagt
     1921 tgctcaacag ttaaaaaatt atgctgataa atacaaaatg aatcctaaag taatttaccc
     1981 tcattctttt aggcatttat ttgctaagaa ttttttagcg aagtataatg atattgcctt
     2041 gcttgcagat ttgatgggac acgaaagtat agaaactact cgaatttatc taaggaaaac
     2101 agctactgaa caacaaaata ttgtagataa aattgttaat tggtaaaaaa taacaggtgg
     2161 tcaaactgac tacctgctat ttttgtgatt atg
//
LOCUS       DAVKUR010000105         2094 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKUR010000105 DAVKUR010000000
VERSION     DAVKUR010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.105"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            39..1049
                     /locus_tag="VW749_002076"
     CDS             39..1049
                     /locus_tag="VW749_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEV0176036.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
     gene            1399..>2094
                     /locus_tag="VW749_002077"
     CDS             1399..>2094
                     /locus_tag="VW749_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEV0176037.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVEN"
BASE COUNT          760 a          246 c          381 g          707 t
ORIGIN      
        1 ctattctgca taatgaagta gaaaatattg cagactcttt ggttattaat aatatttatg
       61 acgaatatcc aatttggagt atacctgtta attttaaagg ttctaaatgg tgtcttgaac
      121 aaacgggtaa tgatatgtat aggggtagag ctggaatatt actgtttatg tactatgtaa
      181 aattattgaa agataaatca tcatatactc aactgtacaa taaaatgtta tctgcaattc
      241 cgccatctgt ttctttatct aagaccacat ttggtttaac tggggatata ggatatttca
      301 ttgttctatc cattatagag gattacgata caaatactct cgcatgctta aattatataa
      361 agagtgtttt aactgagctt gaaaagactg attttgcaag tgtttcaaac aagtctgact
      421 atattaatgg tcttctacct ttaattaata cactggtaag atattatagg agaggaatag
      481 agaaggaacg tgttctaagg ctagtattaa gtttaggtga tacgctatat aatgatgtaa
      541 gcgagagaga taatagtaat tttggatata gttttggcca tggactatca ggtgtaattt
      601 ttacattaaa aaatatttat aaagtgacaa gacttaaaaa atataaagaa ttaattttac
      661 aactagttcc tagggagaaa atcaaaattc attctttgaa gtggtgtagt ggagaatttg
      721 ggacattagt taatcatccc caaagtgttc cagagggaat tgtagctagt ttagataatg
      781 atacattttg ccatggaagt atggccataa taaattttta catcgactac atgaaagaaa
      841 tggatactag tatggaattg gagtctttat tgtgtagtgt tgtaatgaat aaatcaaaag
      901 aaggagagta tcgtatcgtc caaacaagca atttcccaga tttttctttg tatacaggtg
      961 tgactggtat tgcttatact tttttaaggt atatcgcact gaatcagaat gacaaaaaga
     1021 tagttatccc ctcattactt gaaatctagc ttaatttata gttttgtttc taaaatagag
     1081 gtgtccactc attaagcaat ataaaaatac caagattgac tagtttaata tgtaattcta
     1141 taaaatattt ttaatagtgt agcttttcat tgagataata atataataaa gaaaagttct
     1201 attctaattg ctaaacggct tgaggtatat gctactgtta tagaaatgat tttaaactaa
     1261 aatcaaaatt actccaaaaa tagtattgat tttggtttaa tacaaaacat atgtaataat
     1321 gtgagtcaac aaaagtctgt ttttgtacca tactatcttg aaaaatctac taaattcaaa
     1381 ttgagaggat gaattaaaat gaataaaata tttatatatg caggagtgcg aaatcataac
     1441 tctaagactt tagagtatac taagagactt tcaagtatca tttctagtag aaataatgtt
     1501 gatatatctt tcaggacacc tttcaattca gagctagaaa tatctaattc tgattcagaa
     1561 gagttgttta agaaaggaat tgataggcaa agtaatgctg atgatggagg tgttataaaa
     1621 aaagagttat tagagtctga tattataatt atctcttctc ctgtatattt acaaaacgta
     1681 tctgtggaca caaaaaactt tattgaaagg attggggggt ggagccatct ttttcgatta
     1741 gctggaaagt ttgttgtaac attagatgtt gctgagagta acggctctga taatgtgtca
     1801 gaatatctta gagatatatt ttcatatatg ggaggacaga tattacacca agtttcaatt
     1861 accaattcac tcaaagatat tgcagaggct cagttgatgg aggcaactta taaaattgaa
     1921 gatgtacttg aagggaaaat taagtacaaa acaacggatt atcaagaaag agcttaccag
     1981 acattaaaat taattttaga aaattatgat tccgaacatt ttgagaagat gtattgggag
     2041 aaaaaacgcc tttttgaagc taatagttta gaggaatggt attatgttga aaat
//
LOCUS       DAVKUR010000106         2088 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKUR010000106 DAVKUR010000000
VERSION     DAVKUR010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.106"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            54..169
                     /gene="rrf"
                     /locus_tag="VW749_002078"
     rRNA            54..169
                     /gene="rrf"
                     /locus_tag="VW749_002078"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            174..246
                     /locus_tag="VW749_002079"
     tRNA            174..246
                     /locus_tag="VW749_002079"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Val,seq:tac)
     gene            249..321
                     /locus_tag="VW749_002080"
     tRNA            249..321
                     /locus_tag="VW749_002080"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:282..284,aa:Asp,seq:gtc)
     gene            346..418
                     /locus_tag="VW749_002081"
     tRNA            346..418
                     /locus_tag="VW749_002081"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:379..381,aa:Lys,seq:ttt)
     gene            424..505
                     /locus_tag="VW749_002082"
     tRNA            424..505
                     /locus_tag="VW749_002082"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:458..460,aa:Leu,seq:tag)
     gene            524..596
                     /locus_tag="VW749_002083"
     tRNA            524..596
                     /locus_tag="VW749_002083"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:557..559,aa:Thr,seq:tgt)
     gene            619..690
                     /locus_tag="VW749_002084"
     tRNA            619..690
                     /locus_tag="VW749_002084"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:651..653,aa:Gly,seq:gcc)
     gene            698..783
                     /locus_tag="VW749_002085"
     tRNA            698..783
                     /locus_tag="VW749_002085"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:732..734,aa:Leu,seq:taa)
     gene            793..866
                     /locus_tag="VW749_002086"
     tRNA            793..866
                     /locus_tag="VW749_002086"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Arg,seq:acg)
     gene            882..955
                     /locus_tag="VW749_002087"
     tRNA            882..955
                     /locus_tag="VW749_002087"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:916..918,aa:Pro,seq:tgg)
     gene            961..1034
                     /locus_tag="VW749_002088"
     tRNA            961..1034
                     /locus_tag="VW749_002088"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:995..997,aa:Met,seq:cat)
     gene            1048..1121
                     /locus_tag="VW749_002089"
     tRNA            1048..1121
                     /locus_tag="VW749_002089"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1082..1084,aa:Ile,seq:cat)
     gene            1132..1221
                     /locus_tag="VW749_002090"
     tRNA            1132..1221
                     /locus_tag="VW749_002090"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1168..1170,aa:Ser,seq:tga)
     gene            1232..1305
                     /locus_tag="VW749_002091"
     tRNA            1232..1305
                     /locus_tag="VW749_002091"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1266..1268,aa:Met,seq:cat)
     gene            1309..1381
                     /locus_tag="VW749_002092"
     tRNA            1309..1381
                     /locus_tag="VW749_002092"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1342..1344,aa:Phe,seq:gaa)
     gene            1401..1471
                     /locus_tag="VW749_002093"
     tRNA            1401..1471
                     /locus_tag="VW749_002093"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1433..1435,aa:Gly,seq:tcc)
     gene            1507..1580
                     /locus_tag="VW749_002094"
     tRNA            1507..1580
                     /locus_tag="VW749_002094"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1541..1543,aa:Ile,seq:gat)
     gene            1587..1674
                     /locus_tag="VW749_002095"
     tRNA            1587..1674
                     /locus_tag="VW749_002095"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1621..1623,aa:Ser,seq:gct)
     gene            complement(1807..>2088)
                     /locus_tag="VW749_002096"
     CDS             complement(1807..>2088)
                     /locus_tag="VW749_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0176038.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          497 a          431 c          556 g          604 t
ORIGIN      
        1 attgttttct tggtttgaat agatattcaa ttttgagtag gtattactca gagttaagtg
       61 acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag ccctagaacg
      121 ccggaagtag ttgggggttg ccccctgtga gatagggaag tcgcttagct ctagggagtt
      181 tagctcagct gggagagcat ctgccttaca agcagagggt cagcggttcg atcccgttaa
      241 ctcccaaagg tcccgtagtg tagcggttat cacgtcgccc tgtcacggcg aagatcgcgg
      301 gttcgattcc cgtcgggacc gtttaaggta acgcaagtta ttttagactc gttagctcag
      361 ttggtagagc aattgacttt taatcaatgg gtcactggtt cgagcccagt acgggtcata
      421 tatgcgggtt tggcggaatt ggcagacgca ccagatttag gatctggcgc ttaacggcgt
      481 gggggttcaa gtcccttaac ccgcattaag atataacaaa tgagccggct tagctcagtt
      541 ggtagagcat ctgatttgta atcagagggt cgcgtgttca agtcatgtag ccggcatttt
      601 tagatagaag aaaacagtgc gaacgtagtt cagtggtaga acaccacctt gccaaggtgg
      661 gggtcgcggg ttcgaatccc gtcgttcgct tagagaggcc ggggtggcgg aactggcaga
      721 cgcacaggac ttaaaatcct gcgattggta acgatcgtac cggttcgatt ccggtcctcg
      781 gcataatatg gagcaccctt agctcaactg gatagagtac ctgactacga atcaggcggt
      841 tagaggttcg actcctctag ggtgcatttt tctatttaac tcgggaagta gctcagcttg
      901 gtagagtact tggtttggga ccaaggtgtc gcaggttcga atcctgtctt cccgattcat
      961 ggcggtgtag ctcagctggc tagagcgtcc ggttcatacc cgggaggtcg ggggttcgat
     1021 ccccttcgcc gctataatga tcttgtcgga cctttagctc agctggttag agctctcggc
     1081 tcataaccga gtggtcgtag gttcaagtcc tacaaggtcc atttgaatat tggaggatta
     1141 cccaagtccg gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg
     1201 gttcgaatcc cacatcctcc ttttatatta acgcgggatg gagcagctcg gtagctcgtc
     1261 gggctcataa cccgaaggtc gtaggttcaa atcctgctcc cgcaataagg ctcggtagct
     1321 cagttggtag agcaatggat tgaagctcca tgtgtcggcg gttcgattcc gtctcgcgcc
     1381 attttattga tagtatttat gcgggtgtag tttagtggta aaactacagc cttccaagct
     1441 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttcaaatta ccaagttttt
     1501 taacttgggc gcgtagctca ggtggttaga gcgcacgcct gataagcgtg aggtcggtgg
     1561 ttcgagtcca ctcgtgccca ttaattggag aattactcaa gaggctgaag aggacggttt
     1621 gctaaatcgt taggtcgggt aactggcgca agggttcgaa tcccttattc tccgttttaa
     1681 tgagagtttg taactctctt ttttattttt agagacaata aagcttcaga tccgtaaaac
     1741 ttaattgaat tactaatctg aagttatttt taggctcttt gtcaactgta gtgggttgaa
     1801 aaaaagctaa gctcgagaaa ggacaaattt tgtcctttct tttttgatgt tcaaagcgat
     1861 aaaaatcctt tttttgaagt tttcaaagtt ccgaaatcca aaggcgtttc gtttgataag
     1921 tttgatgaga ttatttgtcg cttccagttt ggcgttagaa tagtgtagtt gaagggcgtt
     1981 gacaatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa taggatgaac
     2041 ctgcttcaga ttgtcctcaa taagcccgaa aaatttctct ggttcctt
//
LOCUS       DAVKUR010000107         2040 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKUR010000107 DAVKUR010000000
VERSION     DAVKUR010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.107"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1016
                     /locus_tag="VW749_002097"
     CDS             <1..1016
                     /locus_tag="VW749_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0176039.1"
                     /translation="FFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQ
                     TILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKELNGK
                     ANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLWRD
                     MIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKF
                     WIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDK
                     TLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNACK
                     NAK"
     gene            1006..2013
                     /locus_tag="VW749_002098"
     CDS             1006..2013
                     /locus_tag="VW749_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0176040.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          716 a          290 c          364 g          670 t
ORIGIN      
        1 aattttttct aatagctatt ttagctatgt gtatagtttt tagcgcttgt tcttctaatt
       61 ctgttaaaaa tgaagaaaat acttctaaag agcatgcgcc tgataaaata gttttagatc
      121 atgctttcgg tcaaactata ttagataaaa aacctgaaag agttgcaact attgcttggg
      181 gaaatcatga tgtagcatta gctttaggaa tagttcctgt tggattttca aaagcaaatt
      241 acggtgtaag tgctgataaa ggagttttac catggacaga agaaaaaatc aaagaactaa
      301 atggtaaagc taacctattt gacgatttgg atggacttaa ctttgaagca atatcaaatt
      361 ctaaaccaga tgttatctta gcaggttatt ctggtataac taaagaagat tatgacactc
      421 tatcaaaaat tgctcctgta gcagcataca aatctaaacc ttggcaaact ttatggagag
      481 atatgattaa aattgattca aaagccttag gtatggaaaa agaaggtgat gagttaatca
      541 aaaatactga agctcgtata tccaaagaat tagaaaaaca tccagaaatc aaaggaaaaa
      601 tcaaaggaaa aaaagtatta tttactatga ttaatgctgc agatacatca aaattctgga
      661 tttatactag caaagatcca agagcaaatt atttaacaga tttaggtcta gttttccctg
      721 aatcattaaa agaatttgag agtgaagata gttttgcaaa ggaaatttct gcagaagaag
      781 caaataagat aaatgatgct gatgtaatca taacttatgg tgatgataaa actcttgaag
      841 ctttacaaaa agatcctctt ttaggtaaaa taaatgcaat taaaaatggt gccgttgctg
      901 taattccaga taatacaccg ttagcagcct catgcactcc aacaccactt tcaataaact
      961 atactattga agaataccta aatcttttag gaaatgcatg caaaaatgcg aaataaaaaa
     1021 caaataaacc taggcataat ttttgtaatc tgcctaggtc ttcttattac aatatttttg
     1081 tcattaaagc ttggaacaaa agaaattaat atcagagatt ttttagcagc ttttggaatg
     1141 ggtaatacaa atgatgattt tattaaatca attatatata aaagaatacc tagaactatt
     1201 tttgcaattt tagcaggttc tagtcttgcc ataagcggtg tattgatgca atcagttact
     1261 agaaacccaa tagctgatcc aggtatactc ggtataaaca caggagcaag tcttagtgta
     1321 gtaattggtc tttctttttt aggaatttca tcaagcataa gccatataag ttttgcaatc
     1381 attggtggct tagtaagtgc aatttttgta tacgcgattg ctgtaagcgg aaaagcaggc
     1441 cttaccccta taaaacttgc cttatcagga acttgtgtta gtatggcttt aagcagtttt
     1501 gtaagttttt taattttacc gaataataac gtcttagaca aatttagatt ttggcaaata
     1561 ggtagccttg gagcagctac attatcttct atatctacac tactaccttt tataatttta
     1621 ggtcacttga tagctatatt tatttcatca gatttaaacg ctttagctat gggtgatgaa
     1681 atggctgttg gtcttggagt taatgttaat aggataagat cacttgcaat aattgcaagt
     1741 gtgcttttat gttcaagtat tactgcaatt ggtggaccta ttggcttcgt aggtcttata
     1801 gttcctcact tttgtggctt atttataagc aaagatatac gcacaatgac catttcttca
     1861 tcttttatag gtgcagagct cttgcttata tgtgatataa tcggccgtat gttaggtaaa
     1921 ccaggtgaaa ttgaagtagg gataattact gcaataatcg ggggtccagt acttatttat
     1981 gtaactatga aaaatagagg ggttaataac taatgcaaaa tttaattata ggtattcaaa
//
LOCUS       DAVKUR010000108         1833 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKUR010000108 DAVKUR010000000
VERSION     DAVKUR010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.108"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..212)
                     /locus_tag="VW749_002099"
     CDS             complement(<1..212)
                     /locus_tag="VW749_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176041.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKV"
     gene            complement(240..1001)
                     /locus_tag="VW749_002100"
     CDS             complement(240..1001)
                     /locus_tag="VW749_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0176042.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSGENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(1001..1477)
                     /locus_tag="VW749_002101"
     CDS             complement(1001..1477)
                     /locus_tag="VW749_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0176043.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT          560 a          354 c          241 g          678 t
ORIGIN      
        1 acttttattt tcttattttc aaaaaatata tcatatagtt catcttcagt aatttttcta
       61 tatttcgttg cagtccaatt agaaaatagc ttgtaatcat aagaaacagg tgtatgcaaa
      121 tgaattaaag tcttgtgaaa gctaccgaat ttctctttgg aatttgttag ttcttgataa
      181 acagacttta tcttgttatt aaaccctctc atttctactc tcctaaaaat atcaattgtt
      241 tatttttcaa gtaattcatt aagtctcttt tcccccacct gcaacatctc cttctctacc
      301 tgactccact ccccaaacag taactcttga agaacatctg ctgctgaagt tgtattttct
      361 cctgaatcat atacagaact tctatctcgt tgataaattt gaattctttc aaagatagcc
      421 agttcttcca attgtcgtgt attatcaact agatgattta caatgaaatc atgatgttct
      481 tttggagttg cgcgtgcttg atttggattg ataatgtaca gttcttcata acggataaga
      541 gtacttagat acgacaattc aggctttgtc gcaattaagg ccaattgtac ttcatatccc
      601 ttatttttca agagttgtgc tgttttcttt ggaacatcaa ctgttcgtaa agttccctcg
      661 atcaaaagat tgtatctcaa actactcaat tttgttacta aagactctac catttttcct
      721 gcaaaatctt tggtatattc tacactgtct ttgccatatt cttgctgcag ttctaaatag
      781 tgtggatgct gagaacgaaa actatcacca tctatgataa caatatttcc ttgaaattct
      841 ttctgtttaa tacgatgaat tgtagtctta ccggcaccac tttgacctcc aagcaaaatc
      901 gctataggtt gtttactgga cttttttcct cttgtcagtg aacgaagatt ccttgctaaa
      961 gcatgtttga attcactatc agtataatct tggatttcca ttaagctacc atccgctttt
     1021 cagatatctc taacatacgt tcaattccat ccaaatagcc gctatatctc tctatttcat
     1081 caaaattttc tactaaatag atatttgtct gaatcaagtc agatagatca tcactcatta
     1141 aaatccaagg attagattca tcatcaatgc taattccctg actatcttga taacgataga
     1201 gtcgagataa tagattagca cctctttctt tcacaatttc aattttcaaa gtcaattcat
     1261 aatcttcaac aggattgagc attttatctt ctcctacgat atcgacataa gatacattaa
     1321 acttctgaca aatgatgtct attaattcgg tagagactga actcgttcca ttttcataac
     1381 gactcagact atttcgagaa attcctataa ttcgtgcaaa ttcgggttgt gttaagtcat
     1441 gtgttttacg taaggatttt atgttctttc caatcatagc aaactccttt atttttataa
     1501 atccattata gcataaaaaa gcataacgca ccaaaaatgg tgcgttattt cttgtttttc
     1561 tatcctaaac tttacttcta taaaagtcac ctaaagagct ataaatattt attcttgtat
     1621 taattttttc gatgcgcaaa caatatctac aaatacatct ataacgattc accttttagg
     1681 atttttattg tcaaaattgc ctttatctac aaagacaaaa tgcttataaa atagcttgaa
     1741 attaaggatt atcacctttt tcgttgtagc aacactccac atgtgattat taggctatta
     1801 gcaaagcgta tccaatacct caataaagtg ttg
//
LOCUS       DAVKUR010000109         1760 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKUR010000109 DAVKUR010000000
VERSION     DAVKUR010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.109"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(525..1517)
                     /locus_tag="VW749_002102"
     CDS             complement(525..1517)
                     /locus_tag="VW749_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0176044.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          614 a          284 c          224 g          638 t
ORIGIN      
        1 atagtggatt tacccactac aaatattata gaacccaaaa atgctctgaa acactgattt
       61 caaggcattt tttgttagtt taaaattact cccattcttc ttttccaaac atacaatata
      121 tccaaaacca ttcaaaatac tagattctat tttttataat atcactaaat ccacctaatt
      181 ataggacgtt ttcagatttt tagtcccgtc ccagtcccag taccggagaa atattgtttt
      241 aatataatat ctctttttgt cttctaagct cttaaaagca aaagaacaag taaagagtca
      301 agacaaggat aaaaagtcca tattagggca aataaaaagc tttaagacag atgacaaatc
      361 taagtcaaat aagaaagacc atagcaaagg tgcagagaga taaatattgg cggtcttcgg
      421 actgccttta tttttttatc catttttcaa atcaaattta ttcagactat atatgcacat
      481 atacacttaa attcatataa aaacatggct tgtaaaaaat tactttaatc acaataatcg
      541 catttaaaat tgtgatgttt gcaagctaaa ttacggactt cacttggaag ttttcccttg
      601 tatcttttat aatagataga aaatttgctg gcagatgaat atccaacaga ttctgctatc
      661 tcttttatag gtagttcagt gtttaaaaga agagtttcag ctacattcat tctttttctt
      721 tgagtgtact ctgtaatgct ttgacaatat ttttccttaa ataaattttt taatttagta
      781 ccactcattt tagatatttt ttcaagcgtg ccttgattta cattcgttgc aaaatgatca
      841 tctaagaatc ttgctacatc ttcaagtgct ttatcatcat caatttcaat tttatatttt
      901 tttctattta agtatgtgtc aattactata cttatccatt catttgcctt tgctttaaag
      961 aaaaaatcag cggcaggagc gtccatctta caatttaata tttccattgc cactctttct
     1021 aaggcctttg taagtattat ttgattcggt tgaagcaagg ttgaataaaa agattctgga
     1081 ttaatgttaa tagatgctaa atgtttttct attagctctt ttttaaaacc aatggaaaca
     1141 gcaagataac aacaattctc gtgtaataaa aaaacaaaat catcttttat attatcaaaa
     1201 tcaaaagtac ataaagagtt tgcggtaata gtttgatacg gattaaactt ttctccgttt
     1261 gcactgacaa tgtaacttga ataaattgaa acatagtctg acatactata agtgctattt
     1321 tgaactactt cctctttgat ataaaaatca tgtatatcga taatgaagct gcctccttca
     1381 taaaaccaat ataggccttc tgcataagtt gaattctctt ttttccaaca aaatgtatga
     1441 cctgcacttg aatacttctc attgttttta cattcatcta ctttcatata atcttttaca
     1501 aaatcataat atgacataac acactatccc ttttagacaa tattccaatt agccttatta
     1561 attcaaaact attgtattag taattataac agatgtataa tagaaaagca atgatagata
     1621 ttatcaatta agcgaattta tatctaaaag ggatattaaa gaaaggagat atgcttatga
     1681 agatttacaa aaaactattt gcttatgtcc aagataagaa atatcttggg gttttggcca
     1741 taattttttc tgctatatct
//
LOCUS       DAVKUR010000110         1660 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKUR010000110 DAVKUR010000000
VERSION     DAVKUR010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.110"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(185..737)
                     /locus_tag="VW749_002103"
                     /pseudo
     CDS             complement(185..737)
                     /locus_tag="VW749_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(813..1040)
                     /locus_tag="VW749_002104"
     CDS             complement(813..1040)
                     /locus_tag="VW749_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0176045.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            1068..1253
                     /locus_tag="VW749_002105"
                     /pseudo
     CDS             1068..1253
                     /locus_tag="VW749_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1348..1660
                     /locus_tag="VW749_002106"
                     /pseudo
     CDS             1348..1660
                     /locus_tag="VW749_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          521 a          352 c          294 g          493 t
ORIGIN      
        1 cctctaaaac ctctttgttt acgagagttt cctcgtttgg aagacattct agaagatagg
       61 atagatattt ctcgctattt ataatggatt gaaataagat atgaacaaat cgattaggaa
      121 aggaaaattg atttatagaa atgttttagc agtcgatgcg tactgttata gattcaacgc
      181 actataattg atgacgttta gctgtttcca acaagctcat aataatagct cttgctttag
      241 ctccttcaaa actttgagaa aataaccacc ctcgcttttt taaactgagc tcaggctaaa
      301 agagtccact ggactctttt actccgtccc ataaccaatg atttaatggc gcgttcagct
      361 agattattgg aaaggaccag atgtccgtct ttcaaaatag tcttaaaggt ttcttcatac
      421 ttgaggctgt attcaattgc ccttcctagt tttgaacctg ctaaaactga ctgacggcga
      481 caccaagcaa agaagtcttc cattaggggc tggagatgtt cttgacgttt ctgtagtcgt
      541 tcatcagctg gcaaagcctc ccagtctctt tccaaggaaa ataactgatc acaataagct
      601 aaacctttag ctcctaagga tgatttatct gcttgcttgg gggtcgcttc aaaaaatttc
      661 cttctcacat gcgcccaaca tccaacaagt tcagcttctt ccagttgacg ataagcttct
      721 agcagttcgc agtttaccaa gcttagcgtc gccttgctcc taaaccttgg actgctatcg
      781 cataggcaga actagaggac taaagtccta agttactgcc gcaacatatc acaatgaaca
      841 tagccagaat aatctcctag gaattcttgt actaccgaac cactccgact ctgatcatga
      901 tggtacagcg tgattgcttg attctcaact ttcccagaca aaaaggtcca atagtaggtc
      961 agatggctat gactctctag aacccgataa gaagtttcat ccgcatgaag taagggctga
     1021 gtcaatagtc tctctcgcaa gaggttataa aggggcttta ggaataggag ctttcacaag
     1081 cttatccaga tgattatctt ttactcgtta tggacaatgc tatatggcat aaatcaagta
     1141 ccttaaagat tccgactaat attggttttg catttattcc tccatacaca ccagagatga
     1201 accccattga acaagtgtgg aaagagattc gtaaacgtgg atttatagta aaatgaaata
     1261 ataacaggac aaatcattca ggacagtcaa atcgatttct aacaatgttt tagaagcaga
     1321 ggtgtactat tctagtttca atctactata gataaacttt tgagctattc agaagacttg
     1381 aaacaccact ataatctcta tcaactcttg ctttttcact ttcagaataa ggagcctgac
     1441 aaatttttcg gactcattga ggacaatctg aatcaggttc atcctctaaa accttcctca
     1501 aagataaaga gaagattgtc aatgcccttc aactacacta ttctaatgcc aaactggaag
     1561 cgaccaataa tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa
     1621 acttcaaaaa acggattttc atcgctctga atatcaaaaa
//
LOCUS       DAVKUR010000111         1636 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKUR010000111 DAVKUR010000000
VERSION     DAVKUR010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.111"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            216..947
                     /locus_tag="VW749_002107"
     CDS             216..947
                     /locus_tag="VW749_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0176046.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            965..>1636
                     /locus_tag="VW749_002108"
     CDS             965..>1636
                     /locus_tag="VW749_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-carotene 15,15'-monooxygenase"
                     /protein_id="HEV0176047.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEK"
BASE COUNT          573 a          237 c          271 g          555 t
ORIGIN      
        1 aagctatgtt tacgctttca atcaagtctc atttatgata ctattatggt aatagaaaaa
       61 attcttagtt cgctaaagac ctttattcga gatccagagg aaatagaaat tttatccatt
      121 aaaaatacgt ttcataagtt acttacttga tattaataga attccaatat tgtataatta
      181 aatcaaagat gacactggaa tcaggaggat ttattatggt taataatgta gctgttaaag
      241 tctcaaacct ttcaaaagaa tttttgttag ggcaagacaa aactgtctct attttgaaag
      301 atatttcctt atctgtcaat tatggggaat ttgtatcaat acttggtgtc agtggttctg
      361 gaaagtctac tttgctaagt tgcttatcaa gtttatctga accaacaagt ggcgaagttg
      421 ttatcaatgg tgtaaatcca tataccttaa aagaagggaa gcttgctaaa tttagaagac
      481 aagatattgc aataattttt caaaactata atctggtacc tgctctacct gtactagaaa
      541 atgttacact tcctctgaga ctatcaggaa agagtgttga tagcaataaa gtaaaaaaaa
      601 tgttggatag tttgaatttt aaagcagaac tatcatcatt agttgctacc ttatcaggtg
      661 gagaacagca aaaagtggct attactcgtg caataatagc tgatagtaaa attatttttg
      721 ctgatgagcc aacaggagct ctggacagcg tctcaagaaa acttatattt gaaacacttc
      781 gtaatttagc gagtcaagga aaatgtgttc ttatggtcac tcatgatatt gagttggctt
      841 caaaaactga cagagcactc attttaaaag acggaaaaat atctcgacaa attattaaac
      901 cttcagctga tgagctctac caagcacttg aaagtagtaa agattaattt gaggaggatt
      961 tattatgcta aaattaatca tttaccaatt tcagtactca aaaagacaat ggttaggaac
     1021 aataccatta ctatttgtat ctagcctgat tgttggaaca tctttatttg gtattgctag
     1081 ttcaatcaag actgctaata ttaacgcttc acaacttttt caaatgctaa taatttttgg
     1141 cgggactact ctatttttcc ttatttcaaa taatataaga ctgctaatag atatctttaa
     1201 aaaggattac caattatgga ctatcttagg cgcaagcaga actcagctat ctttattagt
     1261 atctggacag ttttatttaa tggcagtgat tgttagtagt attggtacaa tactttcatt
     1321 tatcatggca gatagttatt acaaattttt acaaaattta ttaggaagag atgagttacc
     1381 tgatttagtt attacagcca acattcaatc aattttattg agtattttta tagtcccaac
     1441 aattgtcggg ataggggctt acttttattc aagtcgaata cttaaaatat catcaatatt
     1501 aaaaccaaaa aagaaaaaaa gaaaagttac agtaactgga tttgttaaca tctctgttcg
     1561 tttattccta tggctactat gtataggttc tattgtttca gcaggtttta tcagaaacaa
     1621 agaaataatt gaaaaa
//
LOCUS       DAVKUR010000112         1526 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKUR010000112 DAVKUR010000000
VERSION     DAVKUR010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.112"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            17..310
                     /locus_tag="VW749_002109"
     CDS             17..310
                     /locus_tag="VW749_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV0176048.1"
                     /translation="MEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAV
                     FESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            624..>1526
                     /locus_tag="VW749_002110"
     CDS             624..>1526
                     /locus_tag="VW749_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV0176049.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEQWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKV"
BASE COUNT          721 a          185 c          271 g          349 t
ORIGIN      
        1 aagtaaaaga ttaagtattg aagaacagat tgaaaagaaa gaagaaagca ttaagcaatt
       61 acaaaatcaa aaaagacagt tgaagaaaaa acttaatgaa caagaaagaa aagcaagaaa
      121 caaaagactt atagaaaaag gtgcagtgtt tgaaagtatt tttgaagaaa gtattgattt
      181 aacaaaagat gaattttata agttaataaa aacgttaaat gatgaagaaa taagattaaa
      241 cataatggaa attttagaag aaagaataga tgataatgta gaaaaatcat ctaaagatga
      301 aataacataa ttgtcccttg gttacaaggg cgcaattata caccctaaag ggtgcttgcg
      361 tcctgcggag tcaaaccctt gcagggagca acaaccattc gctttttaaa agtcaagggt
      421 aaataaactc gctaaggctc gcccttgact tttaaaattt gaaatgaaag taacaattaa
      481 gccgacatac tgaaacaaca aaaattaatt cagtagtcgg cttttttaat tctatcattt
      541 caaaacgctc attcacaaag aggatataaa aaaactatta agcctccacc taaaacaaca
      601 aagaaagaaa ggaagttata aaaatggcag acagttttca tttttcagta aacataatat
      661 caagaggaaa aggcaaaagt gcagtagcaa gtgcagcata tataagtgga gaaaaaataa
      721 aaaatgaatg ggacggagta acccatgact acacaagaaa agaaaaaata ttagtaaaaa
      781 atataatatt gcctgatcat ataccaaaag aatttaatga taggtctacc ttatggaata
      841 aagtagaaat ggcagaaaaa aattctaatg cacaactagc aagacaattc ataataggac
      901 taccaaaaga gttatcttta agtgaaaata aaaacctggt tgaaagatat ataaaagaaa
      961 atttaacatc acaaggaatg atagtagatt atgcaattca tgatgagagt caagataaaa
     1021 atggaaatat ccattgtcat ataatgacca taatgcgacc aataaacgaa aaaggagagt
     1081 tcttagccaa gtcaaaaaaa gaatatatcc tagatgaaaa aggagaaaaa gtattaaaca
     1141 aaaatggaaa accaaagaca agaaaagtag aactaacaac ctggaacgat acaggcaatg
     1201 tagaacaatg gagagaaaat ttttcagatc tttgtaacaa atatttagaa agagcaggag
     1261 cagaaaaaag agtagaccat aggagtttta aaagacaaaa ttcagattat ctaccgacaa
     1321 tccatttagg atcagcagca agtgcaatgg aaagaaaggg aatagaaact gacaagggaa
     1381 actataatag agaaataaga aaatataatc aacttgtaaa aacaataaaa gaagagataa
     1441 aaacattaaa gggttggata ggaaatttat tagataactt atctactgct tatgaaaaat
     1501 ttaaggatat cgaaagagat aaggta
//
LOCUS       DAVKUR010000113         1516 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKUR010000113 DAVKUR010000000
VERSION     DAVKUR010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.113"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..874
                     /locus_tag="VW749_002111"
     CDS             <1..874
                     /locus_tag="VW749_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEV0176050.1"
                     /translation="LLLIIFPNDSLIYYFRLILISLISITLHELGHFLVGRCLSYKLE
                     MLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKNSDRNLVFYFFGGGGANLIV
                     AILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAIREIVLYSKDSKTYQRFFAN
                     SLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVKGEGSAFTIANHEVFDSNIQ
                     ENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSKNNKYLEKIKYLKKLVDFRQ
                     EEIIDFILNKEEVL"
     gene            871..>1516
                     /locus_tag="VW749_002112"
     CDS             871..>1516
                     /locus_tag="VW749_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0176051.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIY"
BASE COUNT          526 a          192 c          230 g          568 t
ORIGIN      
        1 cctattattg ataatttttc caaatgattc attaatctat tattttcgat tgattttaat
       61 ttcgttaata tcaattacat tacatgaact aggtcatttt ttagtgggaa gatgtttatc
      121 ttataaacta gagatgcttg ctactccctt tttcttctat ttcagaaaaa aaatatattt
      181 caaatttcca gtgttattag cattcggtta ttgtcaaatg agtaatagaa acattactaa
      241 tgaaaaaaat agtgatagga atttggtgtt ctacttcttt gggggaggtg gagctaacct
      301 aattgtcgca atattagcac ttttgggatt tgtgccgtac gcatcagaat tttttatttt
      361 gaatataatt ctttttctag ttacggtatg tttaccaatt gatggaacag atggcaatgc
      421 tattagagag atagttttgt attcaaaaga ttcaaaaaca tatcagagat tctttgcgaa
      481 cagtctctat aataatcctt atataacaat cgacgatttt gcaaaattaa cctctaaaga
      541 aaaatctttt ttttcaaaat ttgaaaaatg tttgataaac ctttactttg aagtgaaagg
      601 tgaagggtca gcatttacaa ttgctaatca tgaagttttt gattcaaata ttcaggaaaa
      661 tattatccat gagtactata aattactaca taaatcttct gattggatta ttccacagaa
      721 cttatcttta gaagaagttg tttttacctt gtcaaactat atttactcga aaaataataa
      781 atatttagaa aagattaagt atctaaagaa attagtagat tttagacaag aagaaattat
      841 cgactttatt ttgaacaagg aggaagtatt gtgaaaattc caatgatata tcaaatggaa
      901 aattcagaat gtggattagc atgctgtgcc atgatattga actattttaa atatgagatt
      961 tctttaaatg aactacgtga aatctaccca tcatccagat ctggatattc tctcctatct
     1021 ataagtaaag ttttaggaga ttttaatata agttctcatg cttttaaagc ttcggtaaga
     1081 gatttaaaac cgctcagttt cccactcatt tgcttctggg agagttctca ttttattatt
     1141 cttgaaaaaa ttagtaaaaa caagttttat attttagatc ctgcaaaagg caggcagaga
     1201 atgtcaataa gtgaatttga aaggcattat tcaaatatca ttttaacatt taaaaagtta
     1261 gatagcttta tgtctcgtaa agataataag aagtcgcctg ttttaaagta tttttttaag
     1321 tataggaata agctagggat tttatttttt gtaacagcat tattgtatgt aatacaatca
     1381 ttagtaccta tagctaatag atacataatt gacacgaatt tcaaggacga ttcgtattcg
     1441 tctagaatgt tatttactat attatttata tttactgttt cattctcact aatgtattta
     1501 ttaagacaga tatatg
//
LOCUS       DAVKUR010000114         1469 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKUR010000114 DAVKUR010000000
VERSION     DAVKUR010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.114"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            220..560
                     /gene="tnpB"
                     /locus_tag="VW749_002113"
                     /pseudo
     CDS             220..560
                     /gene="tnpB"
                     /locus_tag="VW749_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(593..1469)
                     /locus_tag="VW749_002114"
                     /pseudo
     CDS             complement(593..1469)
                     /locus_tag="VW749_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          434 a          308 c          266 g          461 t
ORIGIN      
        1 attttttctg tctaactttt tggaaggcag ttcattctac acccactatt atgcgttttt
       61 atcattttga aatctactgc taatcaatga agaagcaaag atcaaactag gcagctagtt
      121 acaagttacg taagcgcgtc ataacaaggt atctatccta attccccaac ttccagtata
      181 ctagataaaa aataattatc ggaggaaagg tattgtacta tgataattca actaagtgat
      241 ttaggtcaag ttcaccttgt ttgtagcaag atagatatga ggcagggaat agactcatta
      301 gcctatgtag ttaaaaccca ctttgaattg gatcctttct ccggtcaagt ctttctcttt
      361 tgtggtggac gtaaagaccg ctttaaagcc ctttactggg atggtcaagg attttggcta
      421 ctatataaac gctttgagaa cggcagactg acttggccca atacagaaaa ggatgtcaaa
      481 gctctcacac ctgaacaagt agactggctt atgacgggct tttctatcac tccaaaaata
      541 aatccatcag aaagtcgtga tttctattga aatgaggact ttctttttat actcatctgc
      601 tttcaaaaag cattctattc catctccgat taacgatgga ctttatcacc tccttctcca
      661 gtccttgtat aacatcttgg agttgattca tgacatcttc caaagttcga aaggctttat
      721 tcttaaatcc acgtttacga atctctttcc acacttgttc aatggggttc atctctggtg
      781 tgtatggagg aataaatgca aagccaatat tagtcggaat ctttaaggta cttgatttat
      841 gccatacagc attgtccata acgagtaaaa gataatcatc tggataagct tgtgaaagct
      901 cttctaaaaa ggcgttcatc cactcagtat tacatccacc agctattaag aaaaatgatt
      961 cgcctgtata ggcatcaaca gctccataac aatagcgaaa ttctcgtata tagtgactat
     1021 ggacatgtag acctactcct attggagacc aacaagatcc cagtttactg attctaccga
     1081 aaccagcctc atcttggtac atcaagcaaa ccttatgaaa acgtctactg gttttaaagc
     1141 gctttctttt cttcttgaat tgagatttta tttttagacg cgacaatggt ttgagcgtct
     1201 gctttcttag gatgttctgg acgtggcata atatttcgcc aaccatggcg cttcaacagt
     1261 tgatagaagg catcacgtgt gtaggaacga cctaactcct ttttataagc ctgaaataag
     1321 gcatcaattg taacaaattc tcctgcctct gcagccttca aatgacgggc aagaaaggct
     1381 ttctcttcct caaccgtcat atatgcatgg ttacgaccac cacgtgtttc ttgaaggaga
     1441 gagtcgagtc cgaactcctc atatttttt
//
LOCUS       DAVKUR010000115         1465 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKUR010000115 DAVKUR010000000
VERSION     DAVKUR010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.115"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>1465)
                     /gene="lanM"
                     /locus_tag="VW749_002115"
     CDS             complement(<1..>1465)
                     /gene="lanM"
                     /locus_tag="VW749_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV0176052.1"
                     /translation="FSSLVFYLEDLIYPWIVKPLVLEINSLREKGLLEGESEQQRYKY
                     FITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEELGLRG
                     KLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIAEYIRKVDEKIRI
                     RIPRTIAYSDHSYEEFIDYLPLEQKKNLPEYYYNFGVLLAFIYLFNGSDIHFENLISY
                     GDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGLDVEMSAL
                     TGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEFDKYIKDFKKGFR
                     DFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLYHPDFYEEMLDRE
                     KALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFGNHFISLHQFSGY
                     DYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYK"
BASE COUNT          510 a          265 c          166 g          524 t
ORIGIN      
        1 aatttatatc ctttttttcg ctgatcaaag cttggaaaat aaatttcaat gatatcaagt
       61 tgcttttcta aattttccaa attattatta ggtaaatatt tcataaaata gtcatatcca
      121 gaaaattgat gtagggaaat aaaatgattt ccaaaatcat cgtagatttc attgatattt
      181 gtatctgtat aaaaaatcgg aatatctaat aacctcattt gttcacattc gcttgctaca
      241 ataccttgat tagaaaactt attgctccag agattttcca atgctttttc tctatctaac
      301 atttcttcat aaaaatcagg atgatataaa aaagatagta ctgaagcata gctatttgtg
      361 tctctaaaaa gtacccttgt ctttaaacca tacaagtttg cttttaatag cattttaaat
      421 tcttctgttt tatttaactc ttcaaatatc agataaaaat ccctaaaacc ttttttgaaa
      481 tcttttatat acttatcaaa ttctatatca ccatcccgaa caggcaggtt tttcccacct
      541 tcaaaatcaa ttttcccaat atcaaacttt accttatcag tatttaaatt aattaaaact
      601 tgaccattaa aagcatcctt cttaaaattt cctgtaagag cactcatctc aacatcaaga
      661 ccatcctccc tttttactcc ctctgttgga agaagcaaag ttcgagtcac cctgtgaaac
      721 agggtatcca gcaaactctg accagtttta tcatcaaata gaggttgctg taacattgtt
      781 tcaaagtcta ttattacagg catatctcca taggaaatta aattttcaaa atgtatatca
      841 ctcccattaa ataaatatat aaatgctaaa agcacaccaa aattataata atattcaggt
      901 aaatttttct tttgctctag aggtagataa tcaataaatt cttcatagct gtgatccgaa
      961 taagcaatag ttcgaggtat tcttatccta attttttcat caacctttcg gatatactca
     1021 gcaatagtat ttagtgagtt attgattatt aaatttttag gcttgtaaac aattttcgcg
     1081 tcatcaaaga agagtatcaa aacagttttt ccttggctgt gtgtatcacc ctttccaaat
     1141 tttatatcat ttaatttccc ccttagccct aattcttctt ctagcacact aaaatcattt
     1201 tctaaatttg ataaaatttc tataaaataa gtatagaacc gaagacaaga ctccgatatt
     1261 tgcctcagta aaacgggata tttgttataa aaatttaata tattctcttc cttgtcaaac
     1321 aatgttataa aatatttgta ccgttgctgc tccgattccc cttcaagtaa acctttttca
     1381 cgcaatgaat ttatctctaa aaccaaaggt ttaacaatcc aaggatagat taaatcttct
     1441 aaataaaata ctagagagga aaaaa
//
LOCUS       DAVKUR010000116         1446 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVKUR010000116 DAVKUR010000000
VERSION     DAVKUR010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.116"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..672
                     /locus_tag="VW749_002116"
                     /pseudo
     CDS             1..672
                     /locus_tag="VW749_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(707..1446)
                     /locus_tag="VW749_002117"
                     /pseudo
     CDS             complement(707..1446)
                     /locus_tag="VW749_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          449 a          244 c          293 g          460 t
ORIGIN      
        1 aggttgatag agatagactt aaaaactatc ttactgacaa tccagacgct tatttgactg
       61 aaatagcttc tgaatttggc tgtcatccaa ctaccatcca ctatgcgctc aaagctatgg
      121 gctacactcg aaaaaaagaa ccacacctac tatgaacaag acccagaaaa agtagcctta
      181 tttcttaaaa attttaatag tttaaagcac ctagcacctg tttatattga tgaaacagga
      241 ttcgatactt atttttatcg agaatatggt cgctcattaa aaggtcagtt aataagaggt
      301 aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgag
      361 ttaatcgctc caatgactta cgaagagatg gtgacgagcg acttttttga agcttggttt
      421 cagaagtttc tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga
      481 ttccatagaa tgggtaagtt agaactttta tgcgaggagt ttgggcataa acttttacct
      541 cttcctccct actcacctga gtacaatcct attgagaaaa catgggctta tatcaaaaag
      601 aacctcaaaa aggtattacc aagttgcaat accttttacg aggctctttt ctcttgttct
      661 tgtttcaatt gactatatta gaggcgagac atttttcggt tctttgtcaa ctgtagtggg
      721 ttgaagaaag cgaagatcta gaaaggacaa atttcgtcct ttcttttttg aagttttcaa
      781 agttcctaaa accaaaggca ttgtgcttga taagtttgat gagattattg gtggcttcca
      841 gtttggcgtt ggaataaggt aattgaaggg cgttgacgat tttctcttta tctttgagga
      901 aggttttaaa cagagtctga aaaagaggtg gaaaagcaag agctgataga gattatagct
      961 gatagagatt atagtggtgt ttcaagtctt cgaatagctc aaaagtttat ctagaatttc
     1021 tttattagtc aagtgcatac gaaaagtagg gcgataaaat cgtttatcac tcagtttctg
     1081 actatcttgt tgaatgagct ccagtagcgc ttgatagcct tgtattcatg ggatttcgga
     1141 tgatggcttg tgttctgctc tcaagaacag ttatgatatt gagcttatca aagtcctgag
     1201 caataaagct catctctatc tcccgattga aacagtcact ccccagactg tttcaacgtc
     1261 ctaggacata atctcaggaa gacgcgaaaa atcatgctca aagtgaaaat cattgatctt
     1321 gcgaatgaca gttgaagttg aaatagacaa ctgatgatca atgtcggtca tagaaatctt
     1381 ttcaattaac ttttgagcaa tcttttggtt gataatacga gggatttggt gattcttctt
     1441 gacgat
//
LOCUS       DAVKUR010000117         1311 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVKUR010000117 DAVKUR010000000
VERSION     DAVKUR010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.117"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..159
                     /locus_tag="VW749_002118"
     CDS             <1..159
                     /locus_tag="VW749_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176053.1"
                     /translation="ELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYREMMK
                     NKKMDQER"
     gene            233..406
                     /locus_tag="VW749_002119"
     CDS             233..406
                     /locus_tag="VW749_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176054.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            592..1119
                     /locus_tag="VW749_002120"
     CDS             592..1119
                     /locus_tag="VW749_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV0176055.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1246..>1311
                     /locus_tag="VW749_002121"
     CDS             1246..>1311
                     /locus_tag="VW749_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0176056.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
BASE COUNT          692 a          176 c          204 g          239 t
ORIGIN      
        1 gaacttggta tagatttatc catagaaata gataagctaa taaaacaggg agaaaaacca
       61 agtgtaatag cacagattaa aaagttccaa gaccaagtca ataaagataa tgaatacaga
      121 gaaatgatga aaaacaagaa aatggatcaa gaaagataag acctggtaaa aatatcttat
      181 ccaagctata atatgaccaa acaactaaag tcagatctag gaggtaatag agatgaataa
      241 aaggcaagag ctaatagatg aactcataaa agcaaatgaa gatggaacat acaaaaccta
      301 taaaagcaca gaagaaataa aagcaatgaa caatgaagaa atacagatta tatattccaa
      361 catgaaaaac tatctatcag acaaaagaac acacataaac tattaaaggt ggaaaggtag
      421 tgtaagctat ttttaaaagt ataaaaggta caaagaccta agaaatatat aaaaacatca
      481 aaataaagta ttccaccacc aagaacaata aaataaaaac aagcaaaggg aagtatagaa
      541 aaattaaaac ctatacttcc cttttttaat tcaaacaaag gagagaaaag catgataaac
      601 gaagaaataa gcaaggaagc aggtcaagca gcacaaacca taatatcata cacaataaag
      661 gcaacaaaag aatcaatcaa tttagaaaaa gaaataagaa aaaagatgaa tgaaacttta
      721 gaaaaagcaa atggaaactt aaaaagtctt atgggcgatg aaatgaaaat aaaagatctc
      781 tacaagaaag gacaactaga aaatataagc atagatcaaa tcgacctcaa agacttaaaa
      841 aaagaactaa acaaacttgg agtaagtttc tcagtaatga aaaacaaaga aagcaaaaac
      901 tatgaaatat tcttccaagc caaagacata aaagtaatgg aatatgcctt taagcaagtc
      961 atagccaagg aaaataaaaa agaaaaagaa agtatcctaa aacaaataaa gaaatacaaa
     1021 gacctatcca aaaacaaaga taagacaaaa gaaaaaggaa aaaggaaagt aaaagaaaaa
     1081 gtaaaaccaa acaaaaaaga tatgaccaga gaaatctaaa gggagtaacg aaaagttaca
     1141 cccttaaata accataataa caagacttcc gaaaaacaga agtccagaat tccgaaaatc
     1201 ggaaatcaag aatttcgatt atcgaaaatc aagaaaggag cagatatggc aacaaacaaa
     1261 agatactatt ggataaaatt aaaagaagaa tttttcacag acaaaaggat a
//
LOCUS       DAVKUR010000118         1267 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVKUR010000118 DAVKUR010000000
VERSION     DAVKUR010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.118"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..265)
                     /locus_tag="VW749_002122"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VW749_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(500..811)
                     /locus_tag="VW749_002123"
     CDS             complement(500..811)
                     /locus_tag="VW749_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176057.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(826..1233)
                     /locus_tag="VW749_002124"
     CDS             complement(826..1233)
                     /locus_tag="VW749_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEV0176058.1"
                     /translation="MWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVVSYD
                     DAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIK
                     VPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          382 a          262 c          218 g          405 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaatg tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactctaga cgcaattcta atcttttaga ctttgcataa
      301 taactgttaa acagttgaaa attaacccag ttttaacaag tagtcaaaat accagataaa
      361 ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat
      421 tatgcgtttt attgtgggaa gatttacttc attttctctt ggaattgagt tttctcctac
      481 ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat
      541 taaagcgaga aaaacaaaag gagcaactta aactttcttt atattgctta tatgttagta
      601 gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct
      661 caaaagggtg attttctaat gaatcatgac accgataaca agcatagtac tttttacaat
      721 catagcattg taaagcaata atatccaact tgctatggta atgaatgcat cttgtttgct
      781 tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag cacgaactgt
      841 gacgctggtt ccatcttcct tataaaaatt gatgagtcct tcttttaatg cacgaaccat
      901 gtctcctgat tgaacgggtt gtgggacttt aatagtcaat agttccattg gatttggagc
      961 gcggtcgatt ttattgcctt tggcatcatg caaatcttca atataggttt caaaatgacg
     1021 gaaacctgga ccataaaact caacttggtc cccttcgtta atgacgtttc gttgacgaat
     1081 ggttgctgtt tgtgccgcat catcataaga aaccacttca gcgacaaact tgtactcagg
     1141 aattttacgg cgagcaccaa acaactgctc attttcagat ggtataccgt agtagaaacc
     1201 tgttgccaat tcacgttggg caaccttcca catctcgtcc accaagtctt gtttgatagc
     1261 ttcaaac
//
LOCUS       DAVKUR010000119         1255 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVKUR010000119 DAVKUR010000000
VERSION     DAVKUR010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.119"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..719
                     /locus_tag="VW749_002125"
     CDS             <1..719
                     /locus_tag="VW749_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0176059.1"
                     /translation="PEEKISVIIGSNGCGKSTLIKTLSRLIKPLEGEVLLDNKSINSY
                     KEKDLAKHIAILPQSPIIPESITVADLVSRGRFPYRKPFKSLGKDDLEIINRSMVKAN
                     VEDLANNLVEELSGGQRQRVWIALALAQDTSILLLDEPTTYLDISYQIELLDLLTDLN
                     QKYKTTICMILHDINLTARYADYLFAIKEGKLVAEGKPEDILNDKLVKDIFNLEAKII
                     RDPISNSPLMIPIGKHHVSS"
BASE COUNT          512 a          197 c          202 g          344 t
ORIGIN      
        1 tacctgaaga aaaaatatca gttattattg ggtcaaatgg ttgtgggaaa tcaacactca
       61 ttaaaacctt gtctcgactt ataaagccat tagagggaga agtattgctt gataataaat
      121 caattaattc ttataaagaa aaagatttag caaaacacat agctatatta cctcaatctc
      181 caataatccc tgaatcaata acagtagctg atcttgtaag ccgtggtcgt ttcccctaca
      241 gaaagccttt taagagtctt ggaaaagatg accttgaaat aataaacaga tcaatggtta
      301 aggccaatgt tgaagatcta gcaaataacc tagttgaaga actttctggg ggtcaaaggc
      361 aaagagtatg gatagctcta gccctagccc aagatacaag tatcctactt ttagatgagc
      421 caactactta cttggatatc tcatatcaaa tagaactatt agacctcttg actgatctaa
      481 accaaaaata taagacaacc atttgcatga ttttgcacga tataaatcta acagcaagat
      541 acgctgatta cctatttgca attaaagaag gtaaacttgt tgcagaggga aagcctgaag
      601 atatactaaa tgataaacta gttaaagata tctttaatct tgaagcaaaa attatacgtg
      661 accctatttc caattcgcct ctaatgattc ctattggcaa gcaccatgtt agctcttaat
      721 aattgaatat cggaattcat ttaaaagtcg caaattttga actgaccctc aaaagttagg
      781 ccaaaaaact aactaaagga ggtcagtttt ttaatggcaa atacagcaca gaatttaaga
      841 taaaattagt aaaagaatat catgaatgaa aaataggata tagagaataa cagcaatatt
      901 aaaaagatca ggactgataa taaaaaaaaa gaaagtacaa cgactagttc aaaagctaaa
      961 acttcaagta aaaagttatt caagaaaatc tagaaaatac tcatcctaca aaggacaggt
     1021 aggaaaaata tcagacaaca aaataaaaag aaatatctat taccgaaaaa aagaggaaat
     1081 cgagtcaagt accaacaggc tcatctattc caaaaagata tttactcgat ggaaaaactc
     1141 ctagaattag tgctacaaat attgacaatg gtatcttagg ttactacgaa gatatagatg
     1201 ataaaaatta tagagttttt gaaaatttta tatctgtttc atttttagga gcagt
//
LOCUS       DAVKUR010000120         1231 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVKUR010000120 DAVKUR010000000
VERSION     DAVKUR010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.120"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..143)
                     /locus_tag="VW749_002126"
     CDS             complement(<1..143)
                     /locus_tag="VW749_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0176060.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEA"
     gene            307..459
                     /gene="rpmG"
                     /locus_tag="VW749_002127"
     CDS             307..459
                     /gene="rpmG"
                     /locus_tag="VW749_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0176061.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            469..645
                     /gene="secE"
                     /locus_tag="VW749_002128"
     CDS             469..645
                     /gene="secE"
                     /locus_tag="VW749_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0176062.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            700..>1231
                     /gene="nusG"
                     /locus_tag="VW749_002129"
     CDS             700..>1231
                     /gene="nusG"
                     /locus_tag="VW749_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0176063.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT          401 a          192 c          241 g          397 t
ORIGIN      
        1 gcttcttttc ctttctgttg ataggctagt aacagacgat tgatttgtct ttcagaaaga
       61 ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc ttttatcaca
      121 agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact attctaccaa
      181 atgggacatt ttcacgttcg atttactaaa gacattatca cattcgaatc acaatagtca
      241 atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga
      301 ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat
      361 tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa attttgtaag
      421 cattgtggca agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt
      481 ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga aagctggaga
      541 gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta catttttgac
      601 cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt
      661 aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaaggg
      721 tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa
      781 cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca
      841 gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat
      901 gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat
      961 gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa
     1021 gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt
     1081 gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt
     1141 acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt
     1201 gcagaagtaa acctaaacca aatcgcagaa t
//
LOCUS       DAVKUR010000121         1184 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVKUR010000121 DAVKUR010000000
VERSION     DAVKUR010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1184
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.121"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..197)
                     /locus_tag="VW749_002130"
     CDS             complement(<1..197)
                     /locus_tag="VW749_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0176064.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDT"
     gene            complement(210..959)
                     /locus_tag="VW749_002131"
     CDS             complement(210..959)
                     /locus_tag="VW749_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0176065.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            complement(971..>1184)
                     /locus_tag="VW749_002132"
     CDS             complement(971..>1184)
                     /locus_tag="VW749_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176066.1"
                     /translation="NFRDKELIFFNKIVNGLIQNIEENLEDDIERILKYLYICLFNEI
                     FIIKNKVNFFDDVEFNQTLSEFLDKL"
BASE COUNT          419 a          224 c          122 g          419 t
ORIGIN      
        1 gtatcaaaaa aagtaatatt taagttattc tcgcaaaaaa acttcataag ctcttcattt
       61 ttagatggaa gaatgccctt ttttaaatta tttattttta cagaatctat atcatatgca
      121 acaactttat atttagatgc aaatagtaac gcgtaggcca gcccaacatg ccccaaacca
      181 attactgcta tattcataaa actacttcct tatttcttaa tccaaaatct aatagaataa
      241 gctgccccat tccttaaata caactcttta atattgttta aaagtttttc aactgatttc
      301 cagattatca aaatctgaga tttatagcac aatattgatg atattctatc aatataatgt
      361 ttttcatcaa gttcctcttg atacattttt aattctttag tttttcccat ataactaacc
      421 atactactat cacttacata tgggaagtcc tcataatata ttactttata acgcataaat
      481 tcaagcgccc ttccaatact attcacaaaa acatgatcaa catggtcacc aagtgaaagc
      541 ggacaatata cgacacattt atcgtctaaa tgcattaaca gctcttttat gatatcattc
      601 tttaatgtgt cctcattttt taattcacta tagatatgac ggtatagaaa attgccattt
      661 ctatctttcc tatagagaca ttcatagtac gataagtgtc taaaatcaca ttgtagacgt
      721 tcacaagcta acctgtcttc tttcttcctt tcttcaatcg gatatttccc aaggttacac
      781 aacttatgaa attgcttagc agagggctgt agctgttggc tcaaagggta accagaaaat
      841 atagtaataa caagtacaat ttctccttct gaagttaatt ttgaaatata atcaccacag
      901 gaaaaaattg cgtcatctaa atgtggagat aaaaagatat acttagtatt gttactcata
      961 accattccct ctacaattta tctaaaaact cactaagtgt ctgattaaat tccacatcat
     1021 caaaaaaatt caccttattc ttaataatga atatttcgtt aaataaacat atatataaat
     1081 atttcaatat cctttcaata tcatcctcta aattctcctc aatattttgt atcagcccat
     1141 ttacaatctt attaaaaaag ataagctctt tatctctaaa atta
//
LOCUS       DAVKUR010000122         1097 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVKUR010000122 DAVKUR010000000
VERSION     DAVKUR010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.122"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..823)
                     /locus_tag="VW749_002133"
     CDS             complement(<1..823)
                     /locus_tag="VW749_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0176067.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVD"
BASE COUNT          329 a          260 c          192 g          316 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaata tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactcatgt ggtttgaaag agtacaacgt ccagagtatg
      301 aaatacacat agctccatgg acaaaggctt caatttcaac atctgtacgt ttgcggattt
      361 cagctaattc ttccattgaa acctcacgcg ctaaaacgac acgagtcaag cctagctctt
      421 tccagaactc aagggtttca tagttagtgg cactggcttg ggtagaaagg tggatttcaa
      481 ggcctggtgc ttcagtcgct gcaatcataa tcaaggctgg gtcagatacg ataactgctg
      541 caatcccgat atcacgcagt ttacggaacc actcaccagc accagcttca tttccttcgt
      601 gcataaccat attagccgct acatagacct tggcaccata cttggtcgca aactgcacgc
      661 cttcttccat ctgttcgaaa gtaaagtttc ccgcacggct acgaagacca taggcctgac
      721 caccgataaa gacagcatct gctccatact gaacagctac ctttagcttc tctaaagtcc
      781 ctgcaggtga taaaacctca ggacgtttta atgtttttgt catgatttct cctatttgca
      841 atataaaagt ttgacatttt tccttctcat tttatagtaa ataaaggata aaatcaagcc
      901 tagacggatt gttttgacaa ttctaatctt ttagactttg cataataact attaaacagt
      961 cgaaaattac cccagtttta acaagtagtc aaaaagtcta aaaaagtaaa aaccagtatc
     1021 ccaagatact gactcgtaaa aatatataaa ttagtcctta gatgactact cccactctgt
     1081 tgctcctata atggaaa
//
LOCUS       DAVKUR010000123         1058 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVKUR010000123 DAVKUR010000000
VERSION     DAVKUR010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.123"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..559
                     /locus_tag="VW749_002134"
     CDS             <1..559
                     /locus_tag="VW749_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0176068.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(513..>1058)
                     /locus_tag="VW749_002135"
     CDS             complement(513..>1058)
                     /locus_tag="VW749_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0176069.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKALTKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT          381 a          168 c          155 g          354 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cttgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat tttcaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgctcagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttaatgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtatc aatgtagtaa
      901 tcgttatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattat taatgcttaa atcgcccttc ttgtaagaaa gacctgtatt cattgaaaaa
     1021 atatctttta tttttataac aacccaattc ataggtat
//
LOCUS       DAVKUR010000124          958 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVKUR010000124 DAVKUR010000000
VERSION     DAVKUR010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.124"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..575
                     /locus_tag="VW749_002136"
     CDS             <1..575
                     /locus_tag="VW749_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0176070.1"
                     /translation="CFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          343 a          110 c          184 g          321 t
ORIGIN      
        1 tttgttttca acgtaatgaa aagtatttaa ttttaggtga aagtggaagc gggaaatcta
       61 cattattaaa attattgaat ggctttttga gagattatag tggagaattg cgattctgcg
      121 gggatgatat aaaaaaaacc tcctatttaa atatggtttc gaatgttcta tatgtagatc
      181 aaaaagctta tttgtttgaa ggtacgatta gagataatat tttattggaa gaaaattata
      241 ctgatgaaga aatactacag tctttagaac aagttggttt gagtgtaaaa gattttccta
      301 ataacatttt agattattat gttggtgatg atgggagatt actgtcagga gggcagaaac
      361 aaaaaattac tttagctaga ggcctaatta gaaataagaa aatagtatta attgacgagg
      421 gaacttctgc tatcgatagg agaacttcgt tagcgattga acgtaagata ttagatagag
      481 aggatttgac tgtcattatt gttacccatg ctccgcatcc ggaacttaaa caatatttta
      541 ctaagatata tcaatttcca aaggatttta tttaagaata taggggaggg aaacatgaga
      601 ttctattgtg aagcttatga ggtaattact gaagagaaaa aagtatcatt tttttatgta
      661 gatgagaaac ccttaaggta tctgttattt gactatatat ttctactagt tctagctaaa
      721 aaaaaatatc ccaatcttat gaactgcacc ccaaaagtta gatttattct gtctaacttt
      781 tggggtgcag ttcattttgc atagttttgg cattcatcct agatatccat ataaaatgtc
      841 tgagattgtt gaaatgtcta aaaaaatatc aaatctaaac gataaaaaag aatttcacaa
      901 aaagaactgt gagttgaggt ttcaagatag tgttcttgat aacataaata gtgtcccg
//
LOCUS       DAVKUR010000125          917 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVKUR010000125 DAVKUR010000000
VERSION     DAVKUR010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.125"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..674
                     /locus_tag="VW749_002137"
     CDS             <1..674
                     /locus_tag="VW749_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0176071.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
BASE COUNT          412 a          117 c          170 g          218 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagcaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtttaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtaggaat tggacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttct
//
LOCUS       DAVKUR010000126          907 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVKUR010000126 DAVKUR010000000
VERSION     DAVKUR010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.126"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..895)
                     /locus_tag="VW749_002138"
     CDS             complement(<1..895)
                     /locus_tag="VW749_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0176072.1"
                     /translation="MGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWS
                     FGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSS
                     LILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFT
                     KLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLT
                     AFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPV
                     GVVTGLLGSPYLIYLLIKMNRR"
BASE COUNT          337 a          158 c          133 g          279 t
ORIGIN      
        1 tcctcctgtt catttttatt agtaaatata ttaagtatgg tgaacctaac aagccagtta
       61 caacacctac tggatatcta gctggtaaaa tattttgaga gaatatgtct gataacaaaa
      121 ctagtaaaat tccaaccaat ccagctaata ttgggcttct tttcttgcca atatttaagg
      181 ctatgggacc agctaaaaaa gatatacaag ctattggtcc tgtaattgaa gtagaaaaag
      241 cagttaaaga tacagcgcaa aaaattaaaa caagccttga aagctcggga tttgctccaa
      301 gtccgattgc tatttcttca ccaagttcaa taatttctag tcttttatta aaaaataaaa
      361 ctaatatagt agcaataata cttactatta gaacaagagg tatgtcatct aactttgtaa
      421 aagataaaga gccactgagc catctcataa cttcttgtaa ttcatatctt gctactttca
      481 acaataaaaa tgaggtgcct gctcttgtga cagcttgaaa accaatgcct aatattatca
      541 gtcttgctgc tgaaaaacca tcttttttag ctagtaaaaa taatattaaa gatgatgtta
      601 gtccacaagt tattgaaata attccagtag ttaaactatt tgtttttaat accaatatgc
      661 aaaagaccgc tgcaatagat gaagaacttg tgacaccgat tatatcagga cttgcaagag
      721 gatttcttaa catagtttga aagataaatc ctgccaatcc aaaagaccag ccagctataa
      781 ttcctgctaa taattttggt aatctaattt ccataatcga aaaactagct ccaggaacag
      841 tttcactatt taagacttta atcaaagttg aaaaagaata actttcatct ccgataagta
      901 aaacgaa
//
LOCUS       DAVKUR010000127          859 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVKUR010000127 DAVKUR010000000
VERSION     DAVKUR010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.127"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            44..>859
                     /locus_tag="VW749_002139"
     CDS             44..>859
                     /locus_tag="VW749_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEV0176073.1"
                     /translation="MQNKTVLVLGAGALGCYISLSLSMYGVRKLIVADYDIIEPSNLN
                     RQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISIKVSSVEELENIVAEYGSIDFIV
                     KAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLIIDNIYIPTIGSCFACRNINKDIN
                     KYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEK
                     YVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLLSGGVAFLSAIGQFTVIET"
BASE COUNT          311 a          106 c          155 g          287 t
ORIGIN      
        1 taaaggttac tattcgttat tttataatga agagtataat aaaatacaga ataaaacagt
       61 attagtatta ggagccggag ccttaggatg ttatatatct ctaagtctaa gtatgtatgg
      121 agtgaggaaa cttattgtcg ctgattacga tataatagaa ccatcaaatt taaataggca
      181 aattctttat acagagtcgg atgttggtaa ggagaagatt aatgttcttt ctcaaaaaat
      241 acacaagtat aattcagatg ttcaggtagt acctatttct attaaagttt cttcagtaga
      301 agaattagaa aacattgttg cggaatatgg gagtatagat tttatcgtta aagcaattga
      361 tacgcccatt gatattataa aaattgtcaa tcaatttgct gtatcgcata agatatccta
      421 catatcagga gggtttaatg gatgctatct tattattgat aatatatata tccctaccat
      481 cggttcttgc tttgcttgtc ggaatataaa caaagatata aataagtaca ctttatctga
      541 taagacaaag tggccgacta caccagagat gcctgctatt ttgggaggga taatgactaa
      601 tttaataatt aaaatatttc tgggatgtta taatgaaatc ctaatagata acgcttacgt
      661 ttataatatg agaaatcatg ctctaagtca agaaaaatat gttctggaaa acggagaatg
      721 tccaatttgt aaaaaaaata ataaagtgaa agataacaat attagagcga aaacatttat
      781 tcgttcagtt tgtttttgct tattatcagg aggagtagct tttttatctg ctattgggca
      841 gttcactgtt atagaaaca
//
LOCUS       DAVKUR010000128          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVKUR010000128 DAVKUR010000000
VERSION     DAVKUR010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.128"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..792
                     /locus_tag="VW749_002140"
     CDS             <1..792
                     /locus_tag="VW749_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY-like element IS1202 family transposase"
                     /protein_id="HEV0176074.1"
                     /translation="FDKQETLNAYYHVLEQILANHGIPLQMKTDKRTVFTYQASNSKK
                     MEDDTYTQFGYACHQLGILLETTSIPQAKGRVERLNQTLQSRLPIELERNKIHTLEEA
                     NTFLLSYIQTFNEQFGNKTKLSVFEEAPNPSERNLILARLAERVVDSGHHIRFQNRCY
                     IPTEQGKEVYFIRKTKALVLKAFDGDIYLNIADKIYHTKELLDHELYSKNFEQEPEQK
                     KERRKYIPPQTHPWKLTSFKQYLHKNKKDYEEFTSEEIHSPQLQV"
BASE COUNT          299 a          200 c          136 g          203 t
ORIGIN      
        1 tttgacaaac aagagacctt gaatgcctac taccatgtcc tcgaacaaat cttagccaat
       61 cacggcattc cccttcaaat gaaaactgat aagagaacgg tctttaccta tcaagcatcc
      121 aactctaaga aaatggagga cgacacctat acacaatttg gatacgcctg tcaccaacta
      181 gggattctcc ttgagaccac ctctatccct caagctaaag ggagggtcga aagactcaat
      241 cagacactac aatcacgcct gcctatcgaa ctggaacgaa acaagattca tacattggaa
      301 gaagccaata ctttccttct ttcctacatc caaaccttta atgaacagtt tggaaataag
      361 acaaaactct ctgtttttga ggaggctcct aacccctctg aacggaatct cattctagct
      421 agactggcgg agagagtcgt cgatagtgga caccatatcc gattccaaaa ccgttgctat
      481 attcctaccg aacaaggaaa agaagtctat ttcatcagaa agacgaaagc attagttcta
      541 aaagcatttg atggtgacat ctacctcaat atcgctgaca aaatctatca cacaaaggag
      601 ctactagatc atgaactcta ttcgaaaaac tttgaacaag aaccagaaca aaaaaaagaa
      661 agacgcaagt atatccctcc acaaacccat ccgtggaaac tcacatcttt caaacaatac
      721 cttcataaaa acaaaaagga ttatgaagag tttactagtg aggagattca ttctcctcaa
      781 ctacaagtat aatctatttt tcgctaaatg ggaagctttt ccttaaagga agtcactc
//
LOCUS       DAVKUR010000129          809 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVKUR010000129 DAVKUR010000000
VERSION     DAVKUR010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.129"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(88..276)
                     /gene="pneA2"
                     /locus_tag="VW749_002141"
     CDS             complement(88..276)
                     /gene="pneA2"
                     /locus_tag="VW749_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEV0176075.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(283..507)
                     /gene="pneA1"
                     /locus_tag="VW749_002142"
     CDS             complement(283..507)
                     /gene="pneA1"
                     /locus_tag="VW749_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEV0176076.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
BASE COUNT          262 a          161 c          101 g          285 t
ORIGIN      
        1 tattgtttta aaaaaaaacc tctctcaaaa ttattagtta cgagagagga aaataaagat
       61 caacttttat ttttaaaatt gaatatttta ttttttcttg ttgtctttgc cacaacgagt
      121 ctgagctgac cccaaatatg atgcaataaa acttaatgta gcagaacata taattgttga
      181 tctagggtca gcaccatctg tgccaccata aaccaattgc atttcttcaa gagataattc
      241 tttcaaactc tttccgatta caaaatcatt tttcatttta atttacccca aacaatcatt
      301 attgtagcta actagccccc caataccaga aacagctgca ctaatgcata ctttcgagct
      361 agctgcagct gatttcaaaa taataggagt aggcgtccaa cgtggctctg caccatcaga
      421 tgcaccataa attaaactca tttcatcagc agacaatgat tttaaacttt ttccacaaaa
      481 tttttcgttt gaattaaagt tggtcataag taataactcc tccttataaa aagttaaata
      541 agttgctcta tatttttcgt tttttcagat aaattataat tctctcattc tcgtgcaaaa
      601 tatcgggttt taatccgcct tcccaacatc aagaccattg gacttctttt gcgattgcac
      661 tcgaatctcc aattgtttat tcttctgaat aaactgttgg taaggaattg tattactaaa
      721 cataaaaaca cctagcaatg caaatgtaac taatttttta attccacgtt tttttctcat
      781 gcaatgaaac ccctttcttt ttccttgtt
//
LOCUS       DAVKUR010000130          806 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVKUR010000130 DAVKUR010000000
VERSION     DAVKUR010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.130"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>806
                     /gene="phtD"
                     /locus_tag="VW749_002143"
     CDS             <1..>806
                     /gene="phtD"
                     /locus_tag="VW749_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0176077.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEP
                     THPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT          285 a          160 c          180 g          181 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga
      241 aatactgagg caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg
      301 ccacttgatc gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta
      361 atcatacctc attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt
      421 tatgaggcac ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc
      481 gaacatccaa acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt
      541 caaagaaaca aaaatggtca agctgatacc aatcaaacgg aaaaaccaaa cgaggagaaa
      601 cctcagacag aaaaacctga ggaagataag gaacatgatg aagtaagtga gccaactcac
      661 cctgaatctg atgaaaaaga gaatcacgct ggtttaaatc cttcagcaga taatctttat
      721 aaaccaagca ctgatacgga agagacagag gaagaagctg aagatactac agatgaggct
      781 gaaattcctc aagtagagca ttctgt
//
LOCUS       DAVKUR010000131          642 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVKUR010000131 DAVKUR010000000
VERSION     DAVKUR010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.131"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            105..584
                     /locus_tag="VW749_002144"
     CDS             105..584
                     /locus_tag="VW749_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0176078.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          242 a           82 c          149 g          169 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagctc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgtgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctaggaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DAVKUR010000132          632 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVKUR010000132 DAVKUR010000000
VERSION     DAVKUR010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.132"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..535
                     /locus_tag="VW749_002145"
                     /pseudo
     CDS             1..535
                     /locus_tag="VW749_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          208 a          113 c          119 g          192 t
ORIGIN      
        1 cgcttatttg actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc
       61 gctcaaagct atgggctaca ctcgaaaaaa aagaaccaca cctactatga acaagagcca
      121 gaaaaagtag ccttatttct taagaatttt aatagtttaa agcacctagc acctgtttag
      181 attgatgaaa caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt
      241 cagttaataa gaggcaaagt atctggaaga agatatcaga gaatttcttt ggttgcaggt
      301 ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga
      361 cttttttgaa gcttggtttc agaagtttct cttaccaaca ttaaccacac catcagttat
      421 tattatggat aatgcaagat tccatagaat gggtaagtta gaactcttgt gtgaagagtt
      481 tgggtataaa cttttacctc ttcctcccta ctcacctgag tacaatccta ttgaggctct
      541 ataatatttg tagtgggtaa atcccctatg gatattatgg agcctatttt tgtgtagaaa
      601 aaaagtccca taagatctat aatgaaaagc ga
//
LOCUS       DAVKUR010000133          596 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVKUR010000133 DAVKUR010000000
VERSION     DAVKUR010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.133"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(29..>596)
                     /locus_tag="VW749_002146"
     CDS             complement(29..>596)
                     /locus_tag="VW749_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0176079.1"
                     /translation="LIKFLMRIFPTENYVINTGFWNLLSNPSYLKSIQTSMSMGVTLI
                     SGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIITSSISLTILSSNKDIEDIK
                     QLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILILVSIIGQFLGRSLVDISG
                     FWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT          228 a           90 c           79 g          199 t
ORIGIN      
        1 ttctttttgg ttcagtaact attccaattt atctatcttg aaataaataa aatccctttg
       61 taatactata aaaaataact aacaaagaaa taactataag actcggttgc cagaaacctg
      121 atatatctac taaactacga cctaaaaatt ggccaataat gctaactaaa attaaaataa
      181 ttaaattgaa aattactgac actaataaaa ttaacaccga atgtattatt gcctcgccta
      241 tacgtatttt aaaaagttgt aatcttgaca ctcccagtgt ctttaactgt ttaatgtcct
      301 caatatcttt attagaagat aaaattgtaa gagaaataga actagtaata atcagaataa
      361 ttggtgcaga catataagca ataaaggaag ctcttgcttc gtttactccg tttgctgtat
      421 tcatgaatga atacatattt tgggtgtaaa gaataaaccc agaaatgaga gttactccca
      481 tgctcattga agtttgtata cttttcaaat agctaggatt ggatagtaga ttccaaaagc
      541 ctgtattaat tacataattt tcagttggaa atatcctcat taaaaatttt attaga
//
LOCUS       DAVKUR010000134          512 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVKUR010000134 DAVKUR010000000
VERSION     DAVKUR010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.134"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>512
                     /locus_tag="VW749_002147"
     CDS             <1..>512
                     /locus_tag="VW749_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0176080.1"
                     /translation="QKDKKGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKIS
                     EVYSILEANYGLVTEREYIDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIE
                     RTETHEEKFTFGRYKVPDSEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRK
                     ILTYSESHRN"
BASE COUNT          200 a           59 c           88 g          165 t
ORIGIN      
        1 atcagaagga taaaaaggga tctattgagg attcagtttt aaatattgta tttgtaacta
       61 cacggacaaa atattgtagt caaattctcc aattattgtt aaagtacttt gataaaaatc
      121 ctaataaaat ttctgaggtt tatagtattc ttgaagcaaa ctacgggttg gttacagaaa
      181 gagaatatat tgattatacc ttagctgaaa ataccatttc tgaacttgct aatcttgatt
      241 tgacgaaaag ttataaccaa gaattaatcg tgacaatttt gaagcagttt cttaaaattg
      301 aaatcgaaag aacagagact catgaagaga aatttacttt tgggcgctat aaagtcccgg
      361 atagtgaaaa attaaaacag tatcatagaa gtatactaaa acttttagcg aatttgtata
      421 atatagggag ttgtgaaact agattttata ttgagaaaat gctatatgat tacagaagaa
      481 aaattttgac ctattcagaa agtcatcgta at
//
LOCUS       DAVKUR010000135          483 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVKUR010000135 DAVKUR010000000
VERSION     DAVKUR010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.135"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..483
                     /locus_tag="VW749_002148"
                     /pseudo
     CDS             1..483
                     /locus_tag="VW749_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT          195 a           47 c           84 g          157 t
ORIGIN      
        1 aatttttata gtttgaatat taaaggattg gaggtaataa aaaataagca acaaaaactt
       61 tttgagaaga gtgggaaaaa actcataaaa taaatacaat tatggttcag ggattatgaa
      121 atcagctaga ttgtaatcat gtagttagta gagatgatct aaatttagta tatgactatt
      181 tattccagaa ggaacgatgg gagtcctatg agataacgct gattggtaat ttatatcatc
      241 tttttgaaat agattatatt tacatggtcg gaaaagaaat actagagcgt acacattatt
      301 acgaaaaaat cggcaagaat agaaatttag ttgtgtcagc ttgtttaaat ttttggttct
      361 gttgccttga aaattcacat ctaatatatg cagactactt tgaaatgaaa ttacaaaaat
      421 tattaaaaga tgacacaaaa gtttttgaaa aatctacatt caaatttgta gaaggatata
      481 aaa
//
LOCUS       DAVKUR010000136          452 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVKUR010000136 DAVKUR010000000
VERSION     DAVKUR010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.136"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..452
                     /locus_tag="VW749_002149"
                     /pseudo
     CDS             1..452
                     /locus_tag="VW749_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          166 a           90 c           73 g          123 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccatct ttatcgaaca
      121 caagggaaat tatgcttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaac acttgatgaa gtactcaatt tacaagctaa aacgcgacag
      241 aaacgaaaat attcttctca taaaggagac gttggcaaga aagcagagaa tctcattcaa
      301 ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac tgaatttgcc
      361 attccagtaa gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa
      421 attatcgcct ataatctttc aacttcaccc aa
//
LOCUS       DAVKUR010000137          375 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVKUR010000137 DAVKUR010000000
VERSION     DAVKUR010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.137"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>375)
                     /locus_tag="VW749_002150"
     CDS             complement(<1..>375)
                     /locus_tag="VW749_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0176081.1"
                     /translation="STVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDN
                     LNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDR
                     FHIIQHLSRAMSRFRVQIMNQF"
BASE COUNT          131 a           70 c           76 g           98 t
ORIGIN      
        1 caaactgatt cataatttga acacgaaaac gactcatggc acggctgaga tgttggataa
       61 tatggaaacg atctagaacg attttagcac acggaaaaag ctgtttagcc aagtcatagt
      121 aaggactaaa catatccatc gtaatgattt tcacttgaca acgaacggct ctatcgtagc
      181 gaagaaagtg atttcggatg acagcttgtg ttctgccttc aagaacagtg ataatattaa
      241 gattatcaaa atcttgcgca atgaaactca tctttccctt agtgaaggca tactcatccc
      301 aagacataat ctttggaagc cgagaaaaat catgctcaaa gtgaaagtca ttgagcttgc
      361 gaatgacagt tgaag
//
LOCUS       DAVKUR010000138          334 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVKUR010000138 DAVKUR010000000
VERSION     DAVKUR010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.138"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>334
                     /locus_tag="VW749_002151"
     CDS             <1..>334
                     /locus_tag="VW749_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEV0176082.1"
                     /translation="ETYKPNVLHFCELLAEEEGIKLSDTTVRKILYKKNILSPKSHRK
                     TKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSRPRKKFAGELIQMDASPHAW
                     FGPETTNL"
BASE COUNT          130 a           76 c           55 g           73 t
ORIGIN      
        1 atgaaacata taaaccaaat gtccttcatt tctgtgaatt actagctgaa gaagagggaa
       61 ttaagctctc tgatacaact gttagaaaaa tactctataa gaaaaacatc ctttctccta
      121 agtctcacag aaagacaaag aagagagtaa gaaaacaagc taaactgaac ctgaatcaac
      181 ccctagacaa tccaatctta ccgacggcta aagacttcct ggaagaccct aaaaaggtac
      241 atcctagtag acccagaaag aaatttgctg gagaactcat tcaaatggat gccagccctc
      301 atgcctggtt tggaccagaa accaccaact taca
//
LOCUS       DAVKUR010000139          298 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00032819
            SAMN33607030-rid17938033.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVKUR010000139 DAVKUR010000000
VERSION     DAVKUR010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607030
            Sequence Read Archive: SRR23726295
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722172.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722172.1
            Genome Coverage       :: 147x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,151
            CDSs (total)                      :: 2,102
            Genes (coding)                    :: 1,965
            CDSs (with protein)               :: 1,965
            Genes (RNA)                       :: 49
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 75 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 39 of 137
            Pseudo Genes (multiple problems)  :: 29 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607030-rid17938033.denovo.140"
                     /strain="AUSMDU00032819"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
BASE COUNT          106 a           29 c           59 g          104 t
ORIGIN      
        1 aatttttgac acctaatatt attgttcgta gtataggagg ggtagttgtt tctatactgc
       61 tttctatatt atatatgaga ggaaggacga aatatgttct acgtaaatag ttatgttttt
      121 gcttataaaa aagaaggtat aatgtatttg cgtggtcgga gtatgcggga aatagctata
      181 gaacctcaaa tttcgcaaga atttatcaac gatctattta atagttgtaa ggaactatta
      241 gagatagaag aagtattagg tagtaaacta acatttgaac tattaaatga acaaattt
//
